DNA mismatch repair defects: Role in colorectal carcinogenesis

Biochimie

Volumn 84, Issue 1, 2002, Pages 27-47

  Jacob, Sandrine ^a   Praz, Françoise ^a  

^a CNRS   (France)

Author keywords

Colorectal carcinogenesis; DNA mismatch repair; Methylation; Tumor suppressor gene

Indexed keywords

POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

CANCER SUSCEPTIBILITY; CARCINOGENESIS; CHEMOSENSITIVITY; COLORECTAL CARCINOMA; DISEASE PREDISPOSITION; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; ESCHERICHIA COLI; FAMILIAL CANCER; FAMILIAL INCIDENCE; GENE DELETION; GENE INSERTION; GENE MUTATION; GENE REPLICATION; GENE TARGETING; GERM LINE; HEREDITY; HUMAN; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; NONHUMAN; PHENOTYPE; PROGNOSIS; PROMOTER REGION; REVIEW; TISSUE SPECIFICITY; TUMOR SUPPRESSOR GENE;

EID: 0036252540     PISSN: 03009084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-9084(01)01362-1     Document Type: Article

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286. Genetic progression in microsatellite instability high (MSI-H) colon cancers correlates with clinicopathological parameters: A study of the TGRbetaRII, BAX, hMSH3, hMSH6, IGFIIR and BLM genes
287. Genomic instability and target gene mutations in colon cancers with different degrees of allelic shifts
288. Systematic identification of genes with coding microsatellites mutated in DNA mismatch repair-deficient cancer cells
289. Lessons from hereditary colorectal cancer
290. Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
291. Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas
292. Mutation analysis of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic human colon cancer using genomic DNA and intron primers
293. HNPCC associated with germline mutation in the TGF-beta type II receptor gene
294. A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite
295. Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC