Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers

Human Molecular Genetics

Volumn 10, Issue 5, 2001, Pages 513-518

  Duval, Alex ^a   Rolland, Sandra ^a   Compoint, Aurore ^a   Tubacher, Emmanuel ^a   Iacopetta, Barry ^b   Thomas, Gilles ^a   Hamelin, Richard ^a  

^a FONDATION JEAN DAUSSET CEPH   (France)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BASE MISPAIRING; CALCULATION; CANCER GROWTH; CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DNA REPAIR; EVOLUTION; GENE MUTATION; GENE TARGETING; GENETIC DISORDER; GENETIC STABILITY; HUMAN; HUMAN CELL; MUTATION RATE; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRESSURE; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 0035283097     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/10.5.513     Document Type: Article

References (30)

1. Clues to the pathogenesis of familial colorectal cancer
2. Microsatellite instability in cancer of the proximal colon
3. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
4. A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
5. BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines
6. Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites
7. Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history
8. Alternative genetic pathways in colorectal carcinogenesis
9. Inactivation of the type II TGF-β eceptor in colon cancer cells with microsatellite instability
10. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumors
11. Frameshift mutator mutations
12. Somatic frameshift mutations in the BX gene in colon cancers of the microsatellite mutator phenotype
13. Frequent frameshift mutations of the TCF-4 gene in colorectal cancers with microsatellite instability
14. Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype
15. A national cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
16. Cloning and characterization of GRB14, a novel member of the GRB7 gene family
17. Human Rad50 is physically associated with human Mre11: Identification of a conserved multiprotein complex implicated in recombinational DNA repair
18. Molecular cloning of a novel hyaluronan receptor that mediates tumor cell motility
19. Allelic profiles of mononucleotide repeat microsatellites in control individuals and in colorectal tumors with and without replication errors
20. Genomic instability and target gene mutations in colon cancers with different degrees of allelic shifts
21. Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis
22. Frequent frameshift mutations of RIZ in sporadic gastrointestinal and endometrial carcinomas with microsatellite instability
23. Involvement of PTEN mutations in the genetic pathways of colorectal cancerogenesis
24. Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency
25. The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability
26. CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers
27. Frameshift mutations in Fas, Apaf-1 and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype
28. A genetic model for colorectal tumorigenesis
29. Mutation of the type II transforming growth factor-β receptor is coincident with the transformation of human colon adenomas to malignant carcinomas
30. Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines