-
1
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E.R. and Vogelstein, B. (1990) A genetic model for colorectal tumorigenesis. Cell, 61, 759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
2
-
-
0023753017
-
Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers
-
Cannon-Albright, L.A., Skolnick, M.H., Bishop, D.T., Lee, R.G. and Burt, R.W. (1988) Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers. N. Engl. J. Med., 319, 533-537.
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 533-537
-
-
Cannon-Albright, L.A.1
Skolnick, M.H.2
Bishop, D.T.3
Lee, R.G.4
Burt, R.W.5
-
3
-
-
0026699483
-
Dominant genes for colorectal cancer are not rare
-
Houlston, R.S., Collins, A., Slack, J. and Morton, N.E. (1992) Dominant genes for colorectal cancer are not rare. Ann. Hum. Genet., 56, 99-103.
-
(1992)
Ann. Hum. Genet.
, vol.56
, pp. 99-103
-
-
Houlston, R.S.1
Collins, A.2
Slack, J.3
Morton, N.E.4
-
4
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel, R., Lescoe, M.K., Rao, M.R., Copeland, N.G., Jenkins, N.A., Garber, J., Kane, M. and Kolodner, R. (1993) The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell, 75, 1027-1038.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.3
Copeland, N.G.4
Jenkins, N.A.5
Garber, J.6
Kane, M.7
Kolodner, R.8
-
5
-
-
0027145633
-
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
-
Leach, F.S., Nicolaides, N.C. Papadopoulos, N. et al. (1993) Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell, 75, 1215-1225.
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
-
6
-
-
0028221943
-
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary nonpolyposis colon cancer
-
Bronner, C.E., Baker, S.M., Morrison, P.T. et al. (1994) Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary nonpolyposis colon cancer. Nature, 368, 258-261.
-
(1994)
Nature
, vol.368
, pp. 258-261
-
-
Bronner, C.E.1
Baker, S.M.2
Morrison, P.T.3
-
7
-
-
0028350601
-
Mutation of a mutL homolog in hereditary colon cancer
-
Papadopoulos, N., Nicolaides, N.C., Wei, Y.F. et al. (1994) Mutation of a mutL homolog in hereditary colon cancer. Science, 263, 1625-1629.
-
(1994)
Science
, vol.263
, pp. 1625-1629
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Wei, Y.F.3
-
8
-
-
0031278322
-
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
-
Miyaki, M., Konishi, M., Tanaka, K. et al. (1997) Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer. Nature Genet., 17, 271-272.
-
(1997)
Nature Genet.
, vol.17
, pp. 271-272
-
-
Miyaki, M.1
Konishi, M.2
Tanaka, K.3
-
9
-
-
0027933070
-
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
-
Nicolaides, N.C., Papadopoulos, N., Liu, B. et al. (1994) Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature, 371, 75-80.
-
(1994)
Nature
, vol.371
, pp. 75-80
-
-
Nicolaides, N.C.1
Papadopoulos, N.2
Liu, B.3
-
10
-
-
0028152314
-
Loss of the wild-type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer
-
Hemminki, A., Peltomaki, P., Mecklin, J.P., Jarvinen, H., Salovaara, R., Nystrom-Lahti, M., de la Chapelle, A. and Aaltonen, L.A. (1994) Loss of the wild-type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer. Nature Genet., 8, 405-410.
-
(1994)
Nature Genet.
, vol.8
, pp. 405-410
-
-
Hemminki, A.1
Peltomaki, P.2
Mecklin, J.P.3
Jarvinen, H.4
Salovaara, R.5
Nystrom-Lahti, M.6
De La Chapelle, A.7
Aaltonen, L.A.8
-
11
-
-
0030747145
-
Reduced frequency of extracolonic cancers in hereditary nonpolyposis colorectal cancer families with monoallelic hMLH1 expression
-
Jäger, A.C., Bisgaard, M.L., Myrhøj, T., Bernstein, I., Rehfeld, J.F. and Nielsen, F.C. (1997) Reduced frequency of extracolonic cancers in hereditary nonpolyposis colorectal cancer families with monoallelic hMLH1 expression. Am. J. Hum. Genet., 61, 129-138.
-
(1997)
Am. J. Hum. Genet.
, vol.61
, pp. 129-138
-
-
Jäger, A.C.1
Bisgaard, M.L.2
Myrhøj, T.3
Bernstein, I.4
Rehfeld, J.F.5
Nielsen, F.C.6
-
12
-
-
0029853804
-
Allele loss occurs frequently at hMLH1, but rarely at hMSH2, in sporadic colorectal cancers with microsatellite instability
-
Tomlinson, I.P, Ilyas, M. and Bodmer, W.F. (1996) Allele loss occurs frequently at hMLH1, but rarely at hMSH2, in sporadic colorectal cancers with microsatellite instability. Br. J. Cancer, 74, 1514-1517.
-
(1996)
Br. J. Cancer
, vol.74
, pp. 1514-1517
-
-
Tomlinson, I.P.1
Ilyas, M.2
Bodmer, W.F.3
-
13
-
-
2942569549
-
Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients
-
Liu, B., Parsons, R., Papadopoulos, N. et al. (1996) Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nature Med., 2, 169-174.
-
(1996)
Nature Med.
, vol.2
, pp. 169-174
-
-
Liu, B.1
Parsons, R.2
Papadopoulos, N.3
-
14
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen, L.A., Peltomaki, P., Leach, F.S. et al. (1993) Clues to the pathogenesis of familial colorectal cancer. Science, 260, 812-816.
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
Peltomaki, P.2
Leach, F.S.3
-
15
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonie carcinogenesis
-
Ionov, Y., Peinado, A., Malkhosyan, S., Shibata, D. and Perucho, M. (1993) Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonie carcinogenesis. Nature, 363, 558-561.
-
(1993)
Nature
, vol.363
, pp. 558-561
-
-
Ionov, Y.1
Peinado, A.2
Malkhosyan, S.3
Shibata, D.4
Perucho, M.5
-
16
-
-
0027136828
-
Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history
-
Lothe, R.A., Peltomaki, P., Meling, G.I. et al. (1993) Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history. Cancer Res., 53, 5849-5852.
-
(1993)
Cancer Res.
, vol.53
, pp. 5849-5852
-
-
Lothe, R.A.1
Peltomaki, P.2
Meling, G.I.3
-
17
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau, S.N., Bren, G. and Schaid, D. (1993) Microsatellite instability in cancer of the proximal colon. Science, 260, 816-819.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
18
-
-
0028859671
-
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
-
Liu, B., Nicolaides, N.C., Markowitz, S. et al. (1995) Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nature Genet., 9, 48-55.
-
(1995)
Nature Genet.
, vol.9
, pp. 48-55
-
-
Liu, B.1
Nicolaides, N.C.2
Markowitz, S.3
-
19
-
-
0030912434
-
Colorectal cancer
-
Dunlop, M.G. (1997) Colorectal cancer. Br. Med. J., 314, 1882-1885.
-
(1997)
Br. Med. J.
, vol.314
, pp. 1882-1885
-
-
Dunlop, M.G.1
-
20
-
-
10144250305
-
Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer
-
Moslein, G., Tester, D.J., Lindor, N.M. et al. (1996) Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer. Hum. Mol. Genet., 5, 1245-1252.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1245-1252
-
-
Moslein, G.1
Tester, D.J.2
Lindor, N.M.3
-
21
-
-
0029897686
-
Genetic heterogeneity and unmapped genes for colorectal cancer
-
Lewis, C.M., Neuhausen, S.L., Daley, D., Black, F.J., Swensen, J., Burt, R.W., Cannon-Albright, L.A. and Skolnick, M.H. (1996) Genetic heterogeneity and unmapped genes for colorectal cancer. Cancer Res., 56, 1382-1388.
-
(1996)
Cancer Res.
, vol.56
, pp. 1382-1388
-
-
Lewis, C.M.1
Neuhausen, S.L.2
Daley, D.3
Black, F.J.4
Swensen, J.5
Burt, R.W.6
Cannon-Albright, L.A.7
Skolnick, M.H.8
-
22
-
-
0031017268
-
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
-
Kane, M.F., Loda, M., Gaida, G.M., Lipman, J., Mishra, R., Goldman, H., Jessup, J.M. and Kolodner, R. (1997) Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res., 57, 808-811.
-
(1997)
Cancer Res.
, vol.57
, pp. 808-811
-
-
Kane, M.F.1
Loda, M.2
Gaida, G.M.3
Lipman, J.4
Mishra, R.5
Goldman, H.6
Jessup, J.M.7
Kolodner, R.8
-
23
-
-
0028907311
-
Alternative splicing of MLH1 messenger RNA in human normal cells
-
Charbonnier, F., Martin, C., Scotte, M., Sibert, L., Moreau, V. and Frebourg, T. (1995) Alternative splicing of MLH1 messenger RNA in human normal cells. Cancer Res., 55, 1839-1841.
-
(1995)
Cancer Res.
, vol.55
, pp. 1839-1841
-
-
Charbonnier, F.1
Martin, C.2
Scotte, M.3
Sibert, L.4
Moreau, V.5
Frebourg, T.6
-
24
-
-
0030977282
-
Microsatellite instability in childhood T cell acute lymphoblastic leukemia
-
Baccichet, A., Benachenhou, N., Couture, F., Leclerc, J.-M. and Sinnett, D. (1997) Microsatellite instability in childhood T cell acute lymphoblastic leukemia. Leukemia, 11, 797-802.
-
(1997)
Leukemia
, vol.11
, pp. 797-802
-
-
Baccichet, A.1
Benachenhou, N.2
Couture, F.3
Leclerc, J.-M.4
Sinnett, D.5
-
25
-
-
0028231090
-
The 1993-94 Genethon human genetic linkage map
-
Gyapay, G., Morissette, J., Vignal, A. et al. (1994) The 1993-94 Genethon human genetic linkage map. Nature Genet., 7, 246-339.
-
(1994)
Nature Genet.
, vol.7
, pp. 246-339
-
-
Gyapay, G.1
Morissette, J.2
Vignal, A.3
-
26
-
-
0029416826
-
An STS-based map of the human genome
-
Hudson, T.J., Stein, L.D., Gerety, S.S. et al. (1995) An STS-based map of the human genome. Science, 270, 1945-1954.
-
(1995)
Science
, vol.270
, pp. 1945-1954
-
-
Hudson, T.J.1
Stein, L.D.2
Gerety, S.S.3
-
27
-
-
0029653615
-
A second-generation YAC contig map of human chromosome 3
-
Gemmill, R.M., Chumakov, I., Scott, P. et al. (1995) A second-generation YAC contig map of human chromosome 3. Nature, 377, 299-319.
-
(1995)
Nature
, vol.377
, pp. 299-319
-
-
Gemmill, R.M.1
Chumakov, I.2
Scott, P.3
-
28
-
-
0024514647
-
Allelotype of colorectal carcinomas
-
Vogelstein, B., Fearon, E.R., Kern, S.E., Hamilton, S.R., Preisinger, A.C., Nakamura, Y. and White, R. (1989) Allelotype of colorectal carcinomas. Science, 244, 207-211.
-
(1989)
Science
, vol.244
, pp. 207-211
-
-
Vogelstein, B.1
Fearon, E.R.2
Kern, S.E.3
Hamilton, S.R.4
Preisinger, A.C.5
Nakamura, Y.6
White, R.7
-
29
-
-
0031807019
-
High resolution deletion mapping reveals frequent allelic losses at the DNA mismatch repair loci hMLH1 and hMSH3 in non-small cell lung cancer
-
Benachenhou, N., Guiral, S., Gorska-Flipot, I., Labuda, D. and Sinnett, D. (1998) High resolution deletion mapping reveals frequent allelic losses at the DNA mismatch repair loci hMLH1 and hMSH3 in non-small cell lung cancer. Int. J. Cancer, 77, 173-180.
-
(1998)
Int. J. Cancer
, vol.77
, pp. 173-180
-
-
Benachenhou, N.1
Guiral, S.2
Gorska-Flipot, I.3
Labuda, D.4
Sinnett, D.5
-
30
-
-
3643142814
-
Frequent loss of heterozygosity at the DNA mismatch-repair loci hMLH1 and hMSH3 in sporadic breast cancer
-
in press
-
Benachenhou, N., Guiral, S., Gorska-Flipot, I., Labuda, D. and Sinnett, D. (1998) Frequent loss of heterozygosity at the DNA mismatch-repair loci hMLH1 and hMSH3 in sporadic breast cancer. Br. J. Cancer (in press).
-
(1998)
Br. J. Cancer
-
-
Benachenhou, N.1
Guiral, S.2
Gorska-Flipot, I.3
Labuda, D.4
Sinnett, D.5
-
31
-
-
0029101616
-
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination and predisposition to cancer
-
de Wind, N., Dekker, M., Berns, A., Radman, M. and te Riele, H. (1995) Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination and predisposition to cancer. Cell, 82, 321-330.
-
(1995)
Cell
, vol.82
, pp. 321-330
-
-
De Wind, N.1
Dekker, M.2
Berns, A.3
Radman, M.4
Te Riele, H.5
-
32
-
-
0030834260
-
Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination
-
Sugawara, N., Paques, F., Colaiacovo, M. and Haber, J.E. (1997) Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination. Proc. Natl Acad. Sci. USA, 94, 9214-9219.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 9214-9219
-
-
Sugawara, N.1
Paques, F.2
Colaiacovo, M.3
Haber, J.E.4
-
33
-
-
0029143992
-
Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint
-
Hawn, M.T., Umar, A., Carethers, J.M., Marra, G., Kunkel, T.A., Boland, C.R. and Koi, M. (1995) Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint. Cancer Res., 55, 3721-3725.
-
(1995)
Cancer Res.
, vol.55
, pp. 3721-3725
-
-
Hawn, M.T.1
Umar, A.2
Carethers, J.M.3
Marra, G.4
Kunkel, T.A.5
Boland, C.R.6
Koi, M.7
-
34
-
-
0029099989
-
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis
-
Baker, S.M., Bronner, C.E., Zhang, L. et al. (1995) Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell, 82, 309-319.
-
(1995)
Cell
, vol.82
, pp. 309-319
-
-
Baker, S.M.1
Bronner, C.E.2
Zhang, L.3
-
35
-
-
8944232867
-
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over
-
Baker, S.M., Plug, A.W., Prolla, T.A. et al. (1996) Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over. Nature Genet., 13, 336-342.
-
(1996)
Nature Genet.
, vol.13
, pp. 336-342
-
-
Baker, S.M.1
Plug, A.W.2
Prolla, T.A.3
-
36
-
-
0029887819
-
Transcription-coupled repair deficiency and mutations in human mismatch repair genes
-
Mellon, I., Rajpal, D.K., Koi, M., Boland, C.R. and Champe, G.N. (1996) Transcription-coupled repair deficiency and mutations in human mismatch repair genes. Science, 272, 557-560.
-
(1996)
Science
, vol.272
, pp. 557-560
-
-
Mellon, I.1
Rajpal, D.K.2
Koi, M.3
Boland, C.R.4
Champe, G.N.5
-
37
-
-
0027292234
-
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
-
Kat, A., Thilly, W.G., Fang, W.H., Longley, M.J., Li, G.M. and Modrich, P. (1993) An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc. Natl Acad. Sci. USA, 90, 6424-6428.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 6424-6428
-
-
Kat, A.1
Thilly, W.G.2
Fang, W.H.3
Longley, M.J.4
Li, G.M.5
Modrich, P.6
-
38
-
-
3643145922
-
Tolerance of oxidative DNA damage results from disruption of Msh2 alleles: Implications for carcinogenesis
-
San Diego, CA
-
De Weese, T.L., Bucci, J.M., Larrier, N.A., Cutler, R.G., te Riele, H. and Nelson, W.G. (1997) Tolerance of oxidative DNA damage results from disruption of Msh2 alleles: implications for carcinogenesis. In Proceedings, 88th Annual Meeting, American Association for Cancer Research, San Diego, CA, vol. 38, p. 540.
-
(1997)
Proceedings, 88th Annual Meeting, American Association for Cancer Research
, vol.38
, pp. 540
-
-
De Weese, T.L.1
Bucci, J.M.2
Larrier, N.A.3
Cutler, R.G.4
Te Riele, H.5
Nelson, W.G.6
-
39
-
-
3643056164
-
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability
-
New Orleans, LA
-
Christensen, E.R., Cunningham, J.M., Tester, D.J., Roche, P.C., Burgart, L.J. and Thibodeau, S.N. (1998) Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. In Proceedings, 89th American Association for Cancer Research, New Orleans, LA, vol. 39, p. 60.
-
(1998)
Proceedings, 89th American Association for Cancer Research
, vol.39
, pp. 60
-
-
Christensen, E.R.1
Cunningham, J.M.2
Tester, D.J.3
Roche, P.C.4
Burgart, L.J.5
Thibodeau, S.N.6
-
40
-
-
0344680330
-
hMLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas
-
New Orleans, LA
-
Esteller, M., Levine, R., Baylin, S.B., Hedrick Ellenson, L. and Herman, J.G. (1998) hMLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas. In Proceedings, 89th American Association for Cancer Research, New Orleans, LA, vol. 39, p. 538.
-
(1998)
Proceedings, 89th American Association for Cancer Research
, vol.39
, pp. 538
-
-
Esteller, M.1
Levine, R.2
Baylin, S.B.3
Hedrick Ellenson, L.4
Herman, J.G.5
-
41
-
-
10344228783
-
Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes
-
Thibodeau, S.N., French, A.J., Roche, P.C. et al. (1996) Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. Cancer Res., 56, 4836-4840.
-
(1996)
Cancer Res.
, vol.56
, pp. 4836-4840
-
-
Thibodeau, S.N.1
French, A.J.2
Roche, P.C.3
-
42
-
-
0029898837
-
DNA methylation errors and cancer
-
Jones, P.A. (1996) DNA methylation errors and cancer. Cancer Res., 56, 2463-2467.
-
(1996)
Cancer Res.
, vol.56
, pp. 2463-2467
-
-
Jones, P.A.1
|