-
1
-
-
2942569549
-
Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients
-
Liu, B., Parsons, R., Papadopoulos, N. et al. (1996) Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nature Med., 2, 169-174.
-
(1996)
Nature Med.
, vol.2
, pp. 169-174
-
-
Liu, B.1
Parsons, R.2
Papadopoulos, N.3
-
2
-
-
0031278322
-
Germline mutation of MSH6 as the cause of hereditary non-polyposis colorectal cancer
-
Miyakaki, M., Konishi, M., Tanaka, K. et al. (1997) Germline mutation of MSH6 as the cause of hereditary non-polyposis colorectal cancer. Nature Genet., 17, 271-272.
-
(1997)
Nature Genet.
, vol.17
, pp. 271-272
-
-
Miyakaki, M.1
Konishi, M.2
Tanaka, K.3
-
3
-
-
0029783835
-
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair
-
Risinger, J.I., Umar, A., Boyd, J., Berchuck, A., Kunkel, T.A. and Barrett, J.C. (1996) Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair. Nature Genet., 14, 102-105.
-
(1996)
Nature Genet.
, vol.14
, pp. 102-105
-
-
Risinger, J.I.1
Umar, A.2
Boyd, J.3
Berchuck, A.4
Kunkel, T.A.5
Barrett, J.C.6
-
4
-
-
0029943449
-
Mismatch repair in replication fidelity, genetic recombination and cancer biology
-
Modrich, P. and Lahue, R. (1996) Mismatch repair in replication fidelity, genetic recombination and cancer biology. Annu. Rev. Biochem., 65, 101-133.
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 101-133
-
-
Modrich, P.1
Lahue, R.2
-
5
-
-
0029070143
-
Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumour cells
-
Drummond, J.T., Li, G.-M., Longley, M.J. and Modrich, P. (1995) Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumour cells. Science, 268, 1909-1912.
-
(1995)
Science
, vol.268
, pp. 1909-1912
-
-
Drummond, J.T.1
Li, G.-M.2
Longley, M.J.3
Modrich, P.4
-
6
-
-
0029659046
-
Binding of insertion/deletion loops in DNA by hMutsβ, a heterodimer of hMSH2 and hMSH3
-
Palombo, F., Iaccarino, I., Nakajima, E., Ikejima, M., Shimada, T. and Jiricny, J. (1996) Binding of insertion/deletion loops in DNA by hMutsβ, a heterodimer of hMSH2 and hMSH3. Curr. Biol., 6, 1181-1184.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1181-1184
-
-
Palombo, F.1
Iaccarino, I.2
Nakajima, E.3
Ikejima, M.4
Shimada, T.5
Jiricny, J.6
-
7
-
-
0028941627
-
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumour cells by a heterodimer of human MutL homologs
-
Li, G.-M. and Modrich, P. (1995) Restoration of mismatch repair to nuclear extracts of H6 colorectal tumour cells by a heterodimer of human MutL homologs. Proc. Natl Acad. Sci. USA, 92, 1950-1954.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 1950-1954
-
-
Li, G.-M.1
Modrich, P.2
-
8
-
-
0030294633
-
Drug-related killings: A case of mistaken identity
-
Karran, P. and Bignami, M. (1996) Drug-related killings: a case of mistaken identity. Chem. Biol., 3, 875-879.
-
(1996)
Chem. Biol.
, vol.3
, pp. 875-879
-
-
Karran, P.1
Bignami, M.2
-
9
-
-
0026750738
-
Self-destruction and tolerance in resistance of mammalian cells to alkylation damage
-
Karran, P. and Bignami, M. (1992) Self-destruction and tolerance in resistance of mammalian cells to alkylation damage. Nucleic Acid Res., 20, 2933-2940.
-
(1992)
Nucleic Acid Res.
, vol.20
, pp. 2933-2940
-
-
Karran, P.1
Bignami, M.2
-
10
-
-
0025195404
-
6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents
-
6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res., 50, 6119-6129.
-
(1990)
Cancer Res.
, vol.50
, pp. 6119-6129
-
-
Pegg, A.E.1
-
12
-
-
0025744481
-
6-alkylguanine-DNA alkyltransferase on the frequency and spectrum of mutations induced by N-methyl-N′-nitro-N-nitrosoguanidine in the HPRT gene of diploid human fibroblasts
-
6-alkylguanine-DNA alkyltransferase on the frequency and spectrum of mutations induced by N-methyl-N′-nitro-N-nitrosoguanidine in the HPRT gene of diploid human fibroblasts. Mutat. Res., 250, 397-409.
-
(1991)
Mutat. Res.
, vol.250
, pp. 397-409
-
-
Lukash, L.L.1
Boldt, J.2
Pegg, A.E.3
Dolan, M.E.4
Maher, V.M.5
McCormick, J.J.6
-
13
-
-
0028533694
-
DNA damage tolerance, mismatch repair and genome instability
-
Karran, P. and Bignami, M. (1994) DNA damage tolerance, mismatch repair and genome instability. Bioessays. 16, 833-839.
-
(1994)
Bioessays.
, vol.16
, pp. 833-839
-
-
Karran, P.1
Bignami, M.2
-
14
-
-
0031975303
-
CCNU sensitivity in mismatch repair defective human cells
-
Aquilina, A., Ceccotti, S., Martinelli, S., Hampson, R. and Bignami, M. (1998) CCNU sensitivity in mismatch repair defective human cells. Cancer Res., 58, 135-141.
-
(1998)
Cancer Res.
, vol.58
, pp. 135-141
-
-
Aquilina, A.1
Ceccotti, S.2
Martinelli, S.3
Hampson, R.4
Bignami, M.5
-
15
-
-
0022971473
-
Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-n′-nitro-N-nitrosoguanidine
-
Goldmacher, V.S., Cuzick, R.A. and Thilly, W.G. (1986) Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine. J. Biol. Chem., 261, 12462-12471.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 12462-12471
-
-
Goldmacher, V.S.1
Cuzick, R.A.2
Thilly, W.G.3
-
16
-
-
0029069972
-
Mutations of GTBP in genetically unstable cells
-
Papadopoulos, N., Nicolaides, N.C., Liu, B. et al. (1995) Mutations of GTBP in genetically unstable cells. Science, 268, 1915-1917.
-
(1995)
Science
, vol.268
, pp. 1915-1917
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Liu, B.3
-
17
-
-
0030667839
-
6-methylguanine-DNA methyltransferase expression in acquired resistance to methylating agents in human cells. J. Biol
-
6-methylguanine-DNA methyltransferase expression in acquired resistance to methylating agents in human cells. J. Biol. Chem., 272, 28596-28606.
-
(1997)
Chem.
, vol.272
, pp. 28596-28606
-
-
Hampson, R.1
Humbert, O.2
Macpherson, P.3
Aquilina, G.4
Karran, P.5
-
18
-
-
0027936057
-
Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrososguanidine tolerance in colon tumour cells with homozygous hMLHI mutation
-
Koi, M., Umar, A., Chauhan, D., Cherian, S.P., Carethers, J.M., Kunkel, T.A. and Boland, C.R. (1994) Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrososguanidine tolerance in colon tumour cells with homozygous hMLHI mutation. Cancer Res., 54, 4308-4312.
-
(1994)
Cancer Res.
, vol.54
, pp. 4308-4312
-
-
Koi, M.1
Umar, A.2
Chauhan, D.3
Cherian, S.P.4
Carethers, J.M.5
Kunkel, T.A.6
Boland, C.R.7
-
19
-
-
0032489486
-
Increased somatic recombination in methylation tolerant human cells with defective DNA mismatch repair
-
Ciotta, C., Ceccotti, S., Aquilina, G., Humbert, O., Palombo, F., Jiricny, J. and Bignami, M. (1998) Increased somatic recombination in methylation tolerant human cells with defective DNA mismatch repair. J. Mol. Biol., 276, 738-743.
-
(1998)
J. Mol. Biol.
, vol.276
, pp. 738-743
-
-
Ciotta, C.1
Ceccotti, S.2
Aquilina, G.3
Humbert, O.4
Palombo, F.5
Jiricny, J.6
Bignami, M.7
-
20
-
-
0029143992
-
Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint
-
Hawn, M.T., Umar, A., Carethers, J.M., Marra, G., Kunkel, T.A., Boland, C.R. and Koi, M. (1995) Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint. Cancer Res., 55, 3721-3725.
-
(1995)
Cancer Res.
, vol.55
, pp. 3721-3725
-
-
Hawn, M.T.1
Umar, A.2
Carethers, J.M.3
Marra, G.4
Kunkel, T.A.5
Boland, C.R.6
Koi, M.7
-
21
-
-
0030885951
-
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base-base mismatch repair
-
Drummond, J.T., Genschel, J., Wolf, E. and Modrich, P. (1997) DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base-base mismatch repair. Proc. Natl Acad. Sci. USA, 94, 10144-10149.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 10144-10149
-
-
Drummond, J.T.1
Genschel, J.2
Wolf, E.3
Modrich, P.4
-
22
-
-
0029031825
-
A mutator phenotype characterizes one of two complementation groups in human cells tolerant to methylation damage
-
Aquilina, G., Hess, P., Fiumicino, S., Ceccotti, S. and Bignami, M. (1995) A mutator phenotype characterizes one of two complementation groups in human cells tolerant to methylation damage. Cancer Res., 55, 2569-2575.
-
(1995)
Cancer Res.
, vol.55
, pp. 2569-2575
-
-
Aquilina, G.1
Hess, P.2
Fiumicino, S.3
Ceccotti, S.4
Bignami, M.5
-
23
-
-
0029101616
-
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination and predisposition to cancer
-
de Wind, N., Dekker, M., Berns, A., Radman, M. and te Riele, H. (1995) Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination and predisposition to cancer. Cell, 82, 321-330.
-
(1995)
Cell
, vol.82
, pp. 321-330
-
-
De Wind, N.1
Dekker, M.2
Berns, A.3
Radman, M.4
Te Riele, H.5
-
24
-
-
0029111463
-
MSH2 deficient mice are viable and susceptible to lymphoid tumours
-
Reitmar, A.H., Schmits, R., Ewel, A. et al. (1995) MSH2 deficient mice are viable and susceptible to lymphoid tumours. Nature Genet., 11, 64-70.
-
(1995)
Nature Genet.
, vol.11
, pp. 64-70
-
-
Reitmar, A.H.1
Schmits, R.2
Ewel, A.3
-
25
-
-
0029099989
-
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapses in meiosis
-
Baker, S.M., Bronner, C.E., Zhang, L. et al. (1995) Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapses in meiosis. Cell, 82, 309-319.
-
(1995)
Cell
, vol.82
, pp. 309-319
-
-
Baker, S.M.1
Bronner, C.E.2
Zhang, L.3
-
26
-
-
8944232867
-
Involvement of mouse Mlhl in DNA mismatch repair and meiotic crossing-over
-
Baker, S.M., Plug, A.W., Prolla, T.A. et al. (1996) Involvement of mouse Mlhl in DNA mismatch repair and meiotic crossing-over. Nature Genet., 13, 336-342.
-
(1996)
Nature Genet.
, vol.13
, pp. 336-342
-
-
Baker, S.M.1
Plug, A.W.2
Prolla, T.A.3
-
27
-
-
15844367099
-
Meiotic pachytene arrest in MLH1-deficient mice
-
Edelmann, W., Cohen, P.E., Kane, M. et al. (1996) Meiotic pachytene arrest in MLH1-deficient mice. Cell, 85, 1125-1134.
-
(1996)
Cell
, vol.85
, pp. 1125-1134
-
-
Edelmann, W.1
Cohen, P.E.2
Kane, M.3
-
28
-
-
0030709433
-
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility
-
Edelmann, W., Yang, K., Umar, A. et al. (1997) Mutation in the mismatch repair gene Msh6 causes cancer susceptibility. Cell, 91, 467-477.
-
(1997)
Cell
, vol.91
, pp. 467-477
-
-
Edelmann, W.1
Yang, K.2
Umar, A.3
-
29
-
-
0020644818
-
6-methylguanine-DNA methyltransferase of human lymphoid cells: Structural and kinetic properties and absence in repair-deficient cells
-
6-methylguanine-DNA methyltransferase of human lymphoid cells: structural and kinetic properties and absence in repair-deficient cells. Cancer Res., 43, 3247-3252.
-
(1983)
Cancer Res.
, vol.43
, pp. 3247-3252
-
-
Harris, A.L.1
Karran, P.2
Lindahl, T.3
-
30
-
-
0024399165
-
Mismatch repair involving localized DNA synthesis in extracts of Xenopus eggs
-
Brooks, P., Dohet, C. Almouzni, G., Mechali, M. and Radman, M. (1989) Mismatch repair involving localized DNA synthesis in extracts of Xenopus eggs. Proc. Natl Acad. Sci. USA, 86, 4425-4429.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 4425-4429
-
-
Brooks, P.1
Dohet, C.A.G.2
Mechali, M.3
Radman, M.4
-
31
-
-
0031469528
-
Reversal of methylation tolerance by transfer of human chromosome 2
-
Aquilina, G., Fiumicino, S., Zijno, A. et al. (1997) Reversal of methylation tolerance by transfer of human chromosome 2. Mutat. Res., 385, 115-126.
-
(1997)
Mutat. Res.
, vol.385
, pp. 115-126
-
-
Aquilina, G.1
Fiumicino, S.2
Zijno, A.3
-
32
-
-
0024312156
-
Normal human chromosome 11 suppresses tumorigenicity of human cervical tumour cell line SiHa
-
Koi, M., Morita, H., Yamada, H., Satoh, H., Barrett, C.J. and Oshimura, M. (1989) Normal human chromosome 11 suppresses tumorigenicity of human cervical tumour cell line SiHa. Mol. Carcinogen., 2, 12-21.
-
(1989)
Mol. Carcinogen.
, vol.2
, pp. 12-21
-
-
Koi, M.1
Morita, H.2
Yamada, H.3
Satoh, H.4
Barrett, C.J.5
Oshimura, M.6
-
33
-
-
0030299847
-
6-methylguanine by mismatch correction in human cell extracts
-
6-methylguanine by mismatch correction in human cell extracts. Curr. Biol., 6, 1528-1531.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1528-1531
-
-
Ceccotti, S.1
Aquilina, G.2
Macpherson, P.3
Yamada, M.4
Karran, P.5
Bignami, M.6
-
34
-
-
0032499218
-
BAX frameshift mutations in cell lines derived from human haematopoietic malignancies are associated with resistance to apoptosis and microsatellite instability
-
Brimmel, M., Mendiola, R., Mangion, J. and Packham, G. (1988) BAX frameshift mutations in cell lines derived from human haematopoietic malignancies are associated with resistance to apoptosis and microsatellite instability. Oncogene, 16, 1803-1812.
-
(1988)
Oncogene
, vol.16
, pp. 1803-1812
-
-
Brimmel, M.1
Mendiola, R.2
Mangion, J.3
Packham, G.4
-
35
-
-
0030776227
-
Correction of hypermutability, MNNG resistance and defective DNA mismatch repair by introducing chromosome 2 into tumour cells with mutations in MSH2 and MSH6
-
Umar, A., Koi, M., Risinger, J.I. et al. (1997) Correction of hypermutability, MNNG resistance and defective DNA mismatch repair by introducing chromosome 2 into tumour cells with mutations in MSH2 and MSH6. Cancer Res., 57, 3949-3955.
-
(1997)
Cancer Res.
, vol.57
, pp. 3949-3955
-
-
Umar, A.1
Koi, M.2
Risinger, J.I.3
-
36
-
-
0029985445
-
Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumour cells
-
Anthoney, D.A., Mcllwrath, A.J., Gallagher, W.M., Edlin, A.R.M. and Brown, R. (1996) Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumour cells. Cancer Res., 56, 1374-1381.
-
(1996)
Cancer Res.
, vol.56
, pp. 1374-1381
-
-
Anthoney, D.A.1
McLlwrath, A.J.2
Gallagher, W.M.3
Edlin, A.R.M.4
Brown, R.5
-
37
-
-
0021287397
-
6-methylguanine produced by N-methyl-N′-nitro-N-nitrosoguanidine in mouse and human cells
-
6-methylguanine produced by N-methyl-N′-nitro-N-nitrosoguanidine in mouse and human cells. Carcinogenesis, 5, 593-600.
-
(1984)
Carcinogenesis
, vol.5
, pp. 593-600
-
-
Yagi, T.1
Yarosh, D.B.2
Day, R.S.3
-
38
-
-
0025941670
-
6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: The role of MGMT in protection against the genotoxic effects of alkylating agents
-
6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents. Carcinogenesis, 12, 1857-1867.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1857-1867
-
-
Kaina, B.1
Fritz, G.2
Mitra, S.3
Coquerelle, T.4
-
39
-
-
0343328947
-
Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair gene
-
Samson, L., Derfler, B. and Waldstein, E. (1986) Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair gene. Proc. Natl Acad. Sci. USA, 83, 5607-5610.
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, pp. 5607-5610
-
-
Samson, L.1
Derfler, B.2
Waldstein, E.3
-
40
-
-
0022994130
-
6-methylguanine methyltransferase gene into repair-deficient human cells and restoration of cellular resistance to N-methyl-N′-nitro-nitrosoguanidine
-
6-methylguanine methyltransferase gene into repair-deficient human cells and restoration of cellular resistance to N-methyl-N′-nitro-nitrosoguanidine. Mutat. Res., 166, 139-141.
-
(1986)
Mutat. Res.
, vol.166
, pp. 139-141
-
-
Ishizaki, K.1
Tsujimura, T.2
Yawata, H.3
Fujio, C.4
Nakabeppu, Y.5
Sekiguchi, M.6
Ikenaga, M.7
-
41
-
-
0022962212
-
Complementation of sensitivity to alkylating agents in Escherichia coli and Chinese hamster ovary cells by expression of a cloned bacterial DNA repair gene
-
Kataoka, H., Hall, J. and Karran, P. (1986) Complementation of sensitivity to alkylating agents in Escherichia coli and Chinese hamster ovary cells by expression of a cloned bacterial DNA repair gene. EMBO J., 5, 3195-3200.
-
(1986)
EMBO J.
, vol.5
, pp. 3195-3200
-
-
Kataoka, H.1
Hall, J.2
Karran, P.3
-
42
-
-
0023001905
-
Reduction of toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene
-
Brennand, L. and Margison, G.P. (1986) Reduction of toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene. Proc. Natl Acad. Sci. USA, 83, 6292-6296.
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, pp. 6292-6296
-
-
Brennand, L.1
Margison, G.P.2
-
43
-
-
0027167456
-
Cloning and characterization of a mouse 3-methyladenine/7-methyl-guanine/3-methylguanine DNA glycosylase cDNA whose gene maps to chromosome 11
-
Engelward, B.P., Boosalis, M.S., Chen, B.J., Deng, Z., Siciliano, M.J. and Samson, L.D. (1993) Cloning and characterization of a mouse 3-methyladenine/7-methyl-guanine/3-methylguanine DNA glycosylase cDNA whose gene maps to chromosome 11. Carcinogenesis, 14, 175-181.
-
(1993)
Carcinogenesis
, vol.14
, pp. 175-181
-
-
Engelward, B.P.1
Boosalis, M.S.2
Chen, B.J.3
Deng, Z.4
Siciliano, M.J.5
Samson, L.D.6
-
44
-
-
0027338194
-
6-methylguanine residues elicit DNA repair synthesis by human cell extracts
-
6-methylguanine residues elicit DNA repair synthesis by human cell extracts. J. Biol. Chem., 268, 15878-15886.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15878-15886
-
-
Karran, P.1
Macpherson, P.2
Ceccotti, S.3
Dogliotti, E.4
Griffin, S.5
Bignami, M.6
-
45
-
-
0030041960
-
Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing
-
Engelward, B.P. Dreslin, A., Christensen, J., Huszar, D., Kurahara, C. and Samson, L. (1996) Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing. EMBO J., 15, 945-952.
-
(1996)
EMBO J.
, vol.15
, pp. 945-952
-
-
Engelward, B.P.1
Dreslin, A.2
Christensen, J.3
Huszar, D.4
Kurahara, C.5
Samson, L.6
-
46
-
-
0026465075
-
Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells
-
Ibeanu, G., Hartenstein, B., Dunn, W.C. et al. (1992) Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells. Carcinogenesis, 13, 1989-1995.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1989-1995
-
-
Ibeanu, G.1
Hartenstein, B.2
Dunn, W.C.3
-
47
-
-
0031426561
-
Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA repair, methyltransferase, had been disrupted by gene targeting
-
Tominaga, Y., Tsuzuki, T., Shiraishi, A., Kawata, H. and Sekiguchi, M. (1997) Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA repair, methyltransferase, had been disrupted by gene targeting. Carcinogenesis, 18, 889-896.
-
(1997)
Carcinogenesis
, vol.18
, pp. 889-896
-
-
Tominaga, Y.1
Tsuzuki, T.2
Shiraishi, A.3
Kawata, H.4
Sekiguchi, M.5
-
48
-
-
0032576768
-
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
-
Aladjem, M.I., Spike, B.T. Rodewald, L.W., Hope, T.J., Klemm, M., Jaenisch, R. and Wahl, G.M. (1997) ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Curr. Biol., 8, 145-155.
-
(1997)
Curr. Biol.
, vol.8
, pp. 145-155
-
-
Aladjem, M.I.1
Spike, B.T.2
Rodewald, L.W.3
Hope, T.J.4
Klemm, M.5
Jaenisch, R.6
Wahl, G.M.7
-
49
-
-
0028245682
-
DNA mismatch binding and incision at modified guanine bases by extracts of mammalian cells: Implications for tolerance to DNA methylation damage
-
Griffin, S., Branch, P., Xu, Y.-Z. and Karran, P. (1994) DNA mismatch binding and incision at modified guanine bases by extracts of mammalian cells: implications for tolerance to DNA methylation damage. Biochemistry, 33, 4787-4793.
-
(1994)
Biochemistry
, vol.33
, pp. 4787-4793
-
-
Griffin, S.1
Branch, P.2
Xu, Y.-Z.3
Karran, P.4
-
50
-
-
0029665878
-
6-methylthymine, or the cisplatin d(GpG) adduct
-
6-methylthymine, or the cisplatin d(GpG) adduct. Proc. Natl Acad. Sci. USA, 93, 6443-6447.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 6443-6447
-
-
Duckett, D.R.1
Drummond, J.T.2
Murchie, A.I.3
Reardon, Y.T.4
Sancar, A.5
Lilley, D.M.6
Modrich, P.7
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