-
1
-
-
74549208765
-
Heredity with reference to carcinoma
-
Warthin AS. Heredity with reference to carcinoma. Arch Intern Med 1913;12:546-55.
-
(1913)
Arch Intern Med
, vol.12
, pp. 546-555
-
-
Warthin, A.S.1
-
2
-
-
0000613653
-
Heredity of carcinoma in man
-
VTarthin AS. Heredity of carcinoma in man. Ann Intern Med 1931 ;4:681-96.
-
(1931)
Ann Intern Med
, vol.4
, pp. 681-696
-
-
Vtarthin, A.S.1
-
3
-
-
0013878809
-
Hereditary factors in cancer
-
Lynch HT, Shaw MV, Magnuson CV, Larsen AL, Krush AJ. Hereditary factors in cancer. Study of two large midwestern kindreds. Arch Intern Med 1966;117:206-12.
-
(1966)
Study of Two Large Midwestern Kindreds. Arch Intern Med
, vol.117
, pp. 206-212
-
-
Lynch, H.T.1
Shaw, M.V.2
Magnuson, C.V.3
Larsen, A.L.4
Krush, A.J.5
-
4
-
-
0015077284
-
Cancer family "G" revisited: 1895-1970
-
Lynch HT, Krush AJ. Cancer family "G" revisited: 1895-1970. Cancer 1971;27:1505-11.
-
(1971)
Cancer
, vol.27
, pp. 1505-1511
-
-
Lynch, H.T.1
Krush, A.J.2
-
6
-
-
0024336005
-
Familial aggregation of tumors in the three-year experience of a population-based colorectal cancer registry
-
ö Ponz de Leon M, Sassatelli R, Sacchetti C, Zanghieri G, Scalmati A, Roncucci L. Familial aggregation of tumors in the three-year experience of a population-based colorectal cancer registry. Cancer Res 1989;49:4344-8.
-
(1989)
Cancer Res
, vol.49
, pp. 4344-4348
-
-
De Ponz Leon, M.1
Sassatelli, R.2
Sacchetti, C.3
Zanghieri, G.4
Scalmati, A.5
Roncucci, L.6
-
8
-
-
0027263363
-
Genetic mapping of a locus predisposing to human colorectal cancer
-
Peltomaki P, Aaltonen LA, Sistonen P, et al. Genetic mapping of a locus predisposing to human colorectal cancer. Science 1993;260:810-12.
-
(1993)
Science
, vol.260
, pp. 810-812
-
-
Peltomaki, P.1
Aaltonen, L.A.2
Sistonen, P.3
-
9
-
-
0027485551
-
Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer
-
Lindblom A, Tannergard P, Verelius B, Nordenskjold M. Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer. Nat Genet 1993;5:279-82.
-
(1993)
Nat Genet
, vol.5
, pp. 279-282
-
-
Lindblom, A.1
Tannergard, P.2
Verelius, B.3
Nordenskjold, M.4
-
10
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen LA, Peltomaki P, Leach FS, et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993;260:812-16.
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
Peltomaki, P.2
Leach, F.S.3
-
11
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel R, Lescoe MK, Rao MR, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993;75:1027-38.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.3
-
12
-
-
0027145633
-
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
-
Leach FS, Nicolaides NC, Papadopoulos N, et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993;75:1215-25.
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
-
13
-
-
0028221943
-
Mutation in the DNA mismatch 'repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer
-
Bronner CE, Baker SM, Morrison PT, et at. Mutation in the DNA mismatch 'repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer. Nature 1994;36S:258-61.
-
(1994)
Nature
, vol.36
, pp. 258-261
-
-
Bronner, C.E.1
Baker, S.M.2
Morrison, P.T.3
At, E.4
-
14
-
-
0028350601
-
Alutation of a mut homolog in hereditary colon cancer
-
Papadopoulos N, Nicolaides NC, Vei YF, et al. Alutation of a mut homolog in hereditary colon cancer. Science 1994;263:1625-9.
-
(1994)
Science
, vol.263
, pp. 1625-1629
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Vei, Y.F.3
-
15
-
-
0029837248
-
Mismatch repair defects in human carcinogenesis
-
Eshleman JR, Markowitz SD. Mismatch repair defects in human carcinogenesis. Hum Mol Genet 1996;5:1489-94.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1489-1494
-
-
Eshleman, J.R.1
Markowitz, S.D.2
-
16
-
-
0027933070
-
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
-
Nicolaides NC, Papadopoulos N, Liu B, ct al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 1994;371:75-80.
-
(1994)
Nature
, vol.371
, pp. 75-80
-
-
Nicolaides, N.C.1
Papadopoulos, N.2
Liu B., C.3
-
17
-
-
0029783835
-
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair
-
Risinger JI, Umar A, Boyd J, Berchuck A, Kunkel TA, Barrett JC. Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair. Nat Genet 1996;14:102-5.
-
(1996)
Nat Genet
, vol.14
, pp. 102-105
-
-
Risinger, J.I.1
Umar, A.2
Boyd, J.3
Berchuck, A.4
Kunkel, T.A.5
Barrett, J.C.6
-
18
-
-
0029008683
-
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells
-
Palombo F, Gallinari P, laccarino I, et al. GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells. Science 1995;26S: 1912-14.
-
(1995)
Science
, vol.26
, pp. 1912-1914
-
-
Palombo, F.1
Gallinari, P.2
Laccarino, I.3
-
19
-
-
0030870631
-
Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred
-
Akiyama Y, Sato H, Yamada T, et al. Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred. Cancer Res 1997;S7:3920-3.
-
(1997)
Cancer Res
, vol.7
, pp. 3920-3923
-
-
Akiyama, Y.1
Sato, H.2
Yamada, T.3
-
20
-
-
0031278322
-
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
-
Miyaki M, Konishi M, Tanaka K, et al. Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer (letter). Nat Genet 1997; 17:271-2.
-
(1997)
Nat Genet
, vol.17
, pp. 271-272
-
-
Miyaki, M.1
Konishi, M.2
Tanaka, K.3
-
21
-
-
0029069972
-
Mutations of GTBP in genetically unstable cells
-
Papadopoulos N, Nicolaides NC, Liu B, el al. Mutations of GTBP in genetically unstable cells. Science 1995;26S:1915-17.
-
(1995)
Science
, vol.26
, pp. 1915-1917
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Liu B., E.3
-
22
-
-
0028226295
-
Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients
-
Aaltonen LA, Peltomaki P, Mecklin JP, et al. Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res 1994;54:1645-8.
-
(1994)
Cancer Res
, vol.54
, pp. 1645-1648
-
-
Aaltonen, L.A.1
Peltomaki, P.2
Mecklin, J.P.3
-
23
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993;260:816-19.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
24
-
-
0032525214
-
Microsatellite instability in human solid tumors
-
Arzimanoglou II, Gilbert F, Barber HR. Microsatellite instability in human solid tumors. Cancer 1998;S2:1808-20.
-
(1998)
Cancer
, vol.2
, pp. 1808-1820
-
-
Gilbert, F.1
Barber, H.R.2
-
25
-
-
0027136828
-
Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history
-
Lothe RA, Peltomaki P, Meling GI, et al. Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history. Cancer Res 1993;53:5849-52.
-
(1993)
Cancer Res
, vol.53
, pp. 5849-5852
-
-
Lothe, R.A.1
Peltomaki, P.2
Meling, G.I.3
-
26
-
-
0028851972
-
Diagnostic use of microsatellite instability in hereditary non-polyposis colorectal cancer
-
Jass JR, Cottier DS, Jeevaratnam P, et ai. Diagnostic use of microsatellite instability in hereditary non-polyposis colorectal cancer. Lancet 1995;346: 1200-1.
-
(1995)
Lancet
, vol.346
, pp. 1200-1201
-
-
Jass, J.R.1
Cottier, D.S.2
Jeevaratnam, P.3
Ai, E.4
-
27
-
-
0032537849
-
Mismatch repair genes and mononucleotide tracts as mutation targets in colorectal tumors with different degrees of microsatellite instability
-
Percesepe A, Kristo P, Aaltonen LA, Ponz de Leon M, de la Chapelle A, Peltomaki P. Mismatch repair genes and mononucleotide tracts as mutation targets in colorectal tumors with different degrees of microsatellite instability. Oncogene 1998;17:157-63.
-
(1998)
Oncogene
, vol.17
, pp. 157-163
-
-
Percesepe, A.1
Kristo, P.2
Aaltonen, L.A.3
De Ponz Leon, M.4
De La Chapelle, A.5
Peltomaki, P.6
-
28
-
-
0031015728
-
BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines
-
Hoang JM, Cottu PH, Thuille B, Salmon RJ, Thomas G, Hamelin R. BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines. Cancer Res 1997;57:300-3.
-
(1997)
Cancer Res
, vol.57
, pp. 300-303
-
-
Hoang, J.M.1
Cottu, P.H.2
Thuille, B.3
Salmon, R.J.4
Thomas, G.5
Hamelin, R.6
-
29
-
-
0032534069
-
A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
-
Boland CR, Thibodeau SN, Hamilton SR, et al. A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;5S:5248-57.
-
(1998)
Cancer Res
, vol.5
, pp. 5248-5257
-
-
Boland, C.R.1
Thibodeau, S.N.2
Hamilton, S.R.3
-
30
-
-
0031551963
-
A National Cancer Institute workshop on hereditary nonpolyposis colorectal cancer syndrome: Meeting highlights and Bethesda guidelines
-
Rodriguez-Bigas MA, Boland CR, Hamilton SR, et al. A National Cancer Institute workshop on hereditary nonpolyposis colorectal cancer syndrome: meeting highlights and Bethesda guidelines. J Nail Cancer Iml 1997;S9: 1758-62.
-
(1997)
J Nail Cancer Iml
, vol.9
, pp. 1758-1762
-
-
Rodriguez-Bigas, M.A.1
Boland, C.R.2
Hamilton, S.R.3
-
31
-
-
0029833872
-
Hereditary nonpolyposis colorectal cancer (Lynch syndrome)
-
Lynch HT, Smyrk T. Hereditary nonpolyposis colorectal cancer (Lynch syndrome). An updated review. Cancer 1996;78:1149-67.
-
(1996)
An Updated Review. Cancer
, vol.78
, pp. 1149-1167
-
-
Lynch, H.T.1
Smyrk, T.2
-
32
-
-
0032924247
-
A century of progress in hereditary nonpolyposis colorectal cancer (Lynch syndrome)
-
Thorson AG, Knezetic JA, Lynch HT. A century of progress in hereditary nonpolyposis colorectal cancer (Lynch syndrome). Dis Colon Rectum 1999; 42:1-9.
-
(1999)
Dis Colon Rectum
, vol.42
, pp. 1-9
-
-
Thorson, A.G.1
Knezetic, J.A.2
Lynch, H.T.3
-
33
-
-
0032555020
-
Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease
-
Aaltonen LA, Salovaara R, Kristo P, et al. Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. NEnglJMed 1998;33S:1481-7.
-
(1998)
NEnglJMed
, vol.33
, pp. 1481-1487
-
-
Aaltonen, L.A.1
Salovaara, R.2
Kristo, P.3
-
35
-
-
0027467494
-
Extracolonic cancer in hereditary nonpolyposis colorectal cancer
-
Watson P, Lynch HT. Extracolonic cancer in hereditary nonpolyposis colorectal cancer. Cancer 1993;71:677-85.
-
(1993)
Cancer
, vol.71
, pp. 677-685
-
-
Watson, P.1
Lynch, H.T.2
-
36
-
-
0031950025
-
Genetics of colonie cancer
-
Lynch HT, Lynch JF. Genetics of colonie cancer. Digestion 1998;59:481-92.
-
(1998)
Digestion
, vol.59
, pp. 481-492
-
-
Lynch, H.T.1
Lynch, J.F.2
-
37
-
-
0028970197
-
The molecular basis of Turcot's syndrome
-
Hamilton SR, Liu B, Parsons RE, et al. The molecular basis of Turcot's syndrome. NEnglJMcd 1995;332:839-47.
-
(1995)
NEnglJMcd
, vol.332
, pp. 839-847
-
-
Hamilton, S.R.1
Liu, B.2
Parsons, R.E.3
-
38
-
-
0033376697
-
Microsatellite instability in benign skin lesions in hereditary non-polyposis colorectal cancer syndrome
-
Swale VJ, Quinn AG, Wheeler JMD, et al. Microsatellite instability in benign skin lesions in hereditary non-polyposis colorectal cancer syndrome. J Im-est Dermatol 1999;113:901-5.
-
(1999)
J Im-est Dermatol
, vol.113
, pp. 901-905
-
-
Swale, V.J.1
Quinn, A.G.2
Jmd, W.3
-
39
-
-
2942569549
-
Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients
-
Liu B, Parsons R, Papadopoulos N, et al. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nat Mcd 1996;2: 169-74.
-
(1996)
Nat Mcd
, vol.2
, pp. 169-174
-
-
Liu, B.1
Parsons, R.2
Papadopoulos, N.3
-
40
-
-
0031012805
-
Cancer risk associated with germline DNA mismatch repair gene mutations
-
Dunlop MG, Farrington SM, Carothers AD, et al. Cancer risk associated with germline DNA mismatch repair gene mutations. Hum Mol Genet 1997;6:105-10.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 105-110
-
-
Dunlop, M.G.1
Farrington, S.M.2
Carothers, A.D.3
-
41
-
-
0029862873
-
Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis
-
Vasen HF, Wijnen JT, Menko FH, et al. Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis. Gastroemerology 1996;110:1020-7.
-
(1996)
Gastroemerology
, vol.110
, pp. 1020-1027
-
-
Vasen, H.F.1
Wijnen, J.T.2
Menko, F.H.3
-
43
-
-
0025848680
-
The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICGHNPCC)
-
Vasen HF, Mecklin JP, Khan PM, Lynch HT. The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICGHNPCC). OH Colon Rectum 1991;34:424-5.
-
(1991)
OH Colon Rectum
, vol.34
, pp. 424-425
-
-
Vasen, H.F.1
Mecklin, J.P.2
Khan, P.M.3
Lynch, H.T.4
-
44
-
-
0033063711
-
New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch Syndrome) proposed by the International Collaborative Group on HNPCC
-
Vasen HFA, Ytatson P, Mecklin JP, Lynch HT. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch Syndrome) proposed by the International Collaborative Group on HNPCC. Gasirocnterology 1999;! 16:1453-6.
-
(1999)
Gasirocnterology
, vol.16
, pp. 1453-1456
-
-
Hfa, V.1
Ytatson, P.2
Mecklin, J.P.3
Lynch, H.T.4
-
45
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonie carcinogenesis
-
lonov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonie carcinogenesis. Nature 1993;363:558-61.
-
(1993)
Nature
, vol.363
, pp. 558-561
-
-
Peinado, M.A.1
Malkhosyan, S.2
Shibata, D.3
Perucho, M.4
-
46
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson AG Mutation and cancer: statistical study of retinoblastoma. Proc Nad Acad Sei USA 1971;6S:820-3.
-
(1971)
Proc Nad Acad Sei USA
, vol.6
, pp. 820-823
-
-
Knudson, A.G.1
-
47
-
-
0028859671
-
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
-
Liu B, Nicolaides NC, Markowitz S, et al. Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nat Genet 1995; 9:48-55.
-
(1995)
Nat Genet
, vol.9
, pp. 48-55
-
-
Liu, B.1
Nicolaides, N.C.2
Markowitz, S.3
-
48
-
-
0028845722
-
Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas
-
Borresen AL, Lothe RA, Meling GI, el al. Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas. Hum Mol Genet 1995;4:2065-72.
-
(1995)
Hum Mol Genet
, vol.4
, pp. 2065-2072
-
-
Borresen, A.L.1
Lothe, R.A.2
Meling G.I., E.3
-
49
-
-
0028883556
-
Aïutations in DMA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas
-
Katabuchi H, van Rees B, Lambers AR, et al. Aïutations in DMA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas. Cancer Res 1995;55:5556-60.
-
(1995)
Cancer Res
, vol.55
, pp. 5556-5560
-
-
Katabuchi, H.1
Van Rees, B.2
Lambers, A.R.3
-
50
-
-
0029597808
-
Microsatellite instability and alterations in the hMSH2 gene in human ovarian cancer
-
Fujita M, Enomoto T, Yoshino K, et al. Microsatellite instability and alterations in the hMSH2 gene in human ovarian cancer. Im J Cancer 1995;64: 361-6.
-
(1995)
Im J Cancer
, vol.64
, pp. 361-366
-
-
Fujita, M.1
Enomoto, T.2
Yoshino, K.3
-
51
-
-
0032522658
-
Microsatellite instability in colorectal cancer: Different mutator phenotypes and the principal involvement of hMLH 1
-
Thibodeau SN, French AJ, Cunningham JM, et al. Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH 1. Cancer Res 1998;58:1713-18.
-
(1998)
Cancer Res
, vol.58
, pp. 1713-1718
-
-
Thibodeau, S.N.1
French, A.J.2
Cunningham, J.M.3
-
52
-
-
0029784320
-
Biochemistry and genetics of eukaryotic mismatch repair
-
Kolodner R. Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev 1996;10:1433-42.
-
(1996)
Genes Dev
, vol.10
, pp. 1433-1442
-
-
Kolodner, R.1
-
53
-
-
0029868110
-
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair
-
Marsischky GT, Filosi N, Kane MF, Kolodner R. Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dcv 1996;10:407-20.
-
(1996)
Genes Dcv
, vol.10
, pp. 407-420
-
-
Marsischky, G.T.1
Filosi, N.2
Kane, M.F.3
Kolodner, R.4
-
54
-
-
0030953472
-
Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins
-
Greene CN, Jinks-Robertson S. Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins. Mol Cell Biol 1997;17:2844-50.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2844-2850
-
-
Greene, C.N.1
Jinks-Robertson, S.2
-
55
-
-
0030897578
-
Microsatellite instability in yeast: Dependence on repeat unit size and DMA mismatch repair genes
-
Sia EA, Kokoska RJ, Dominska M, Greenwell P, Petes TD. Microsatellite instability in yeast: dependence on repeat unit size and DMA mismatch repair genes. Mol Cell Biol 1997;17:2851-8.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2851-2858
-
-
Sia, E.A.1
Kokoska, R.J.2
Dominska, M.3
Greenwell, P.4
Petes, T.D.5
-
56
-
-
0032584384
-
Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha
-
Genschel J, Littman SJ, Drummond JT, Modrich P. Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha. JBiolChem 1998;273:19895-901.
-
(1998)
JBiolChem
, vol.273
, pp. 19895-19901
-
-
Genschel, J.1
Littman, S.J.2
Drummond, J.T.3
Modrich, P.4
-
57
-
-
0029659046
-
MutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion deletion loops in DNA
-
Palombo F, laccarino I, Nakajima E, Ikejima M, Shimada T, Jiricny J. hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion deletion loops in DNA. CurrBiol 1996;6:1181-4.
-
(1996)
CurrBiol
, vol.6
, pp. 1181-1184
-
-
Palombo, F.1
Laccarino, I.2
Nakajima, E.3
Ikejima, M.4
Shimada, T.5
-
58
-
-
0030250603
-
Binding of insertion/deletion DMA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3
-
Habraken Y, Sung P, Prakash L, Prakash S. Binding of insertion/deletion DMA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3. CurrBiol 1996;6:1185-7.
-
(1996)
CurrBiol
, vol.6
, pp. 1185-1187
-
-
Habraken, Y.1
Sung, P.2
Prakash, L.3
Prakash, S.4
-
59
-
-
0029813614
-
The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DXA base pairs
-
Alani E. The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DXA base pairs. Mol Cell Biol 1996;16:5604-15.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5604-5615
-
-
Alani, E.1
-
60
-
-
0029070143
-
Isolation of an hMSH2-p 160 heterodimer that restores DNA mismatch repair to tumor cells
-
Drummond JT, Li GM, Longley MJ, Modrich P. Isolation of an hMSH2-p 160 heterodimer that restores DNA mismatch repair to tumor cells. Science 1995;26S:1909-12.
-
(1995)
Science
, vol.26
, pp. 1909-1912
-
-
Drummond, J.T.1
Li, G.M.2
Longley, M.J.3
Modrich, P.4
-
61
-
-
33847554185
-
MLHI, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast
-
Prolla TA, Pang Q, Alan; E, Kolodner RD, Liskay RM. MLHI, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science l991;265:109l-3.
-
Science L991
, vol.265
-
-
Prolla, T.A.1
Pang Q.an, E.2
Kolodner, R.D.3
Liskay, R.M.4
-
62
-
-
0028941627
-
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs
-
Li GM, Modrich P. Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. Proc Nail Acad Sei USA 1995;92:1950-4.
-
(1995)
Proc Nail Acad Sei USA
, vol.92
, pp. 1950-1954
-
-
Li, G.M.1
Modrich, P.2
-
63
-
-
0031260535
-
Enhancement of MSH2-MSH3mediated mismatch recognition by the yeast MLH 1-PMS 1 complex
-
Habraken Y, Sung P, Prakash L, Prakash S. Enhancement of MSH2-MSH3mediated mismatch recognition by the yeast MLH 1-PMS 1 complex. Curr Biol 1997;7:790-3.
-
(1997)
Curr Biol
, vol.7
, pp. 790-793
-
-
Habraken, Y.1
Sung, P.2
Prakash, L.3
Prakash, S.4
-
64
-
-
0032514709
-
The Saccharomyces cerevisiae MLH3 gene functions in AlSH3-dependent suppression of frameshift mutations
-
Flores-Rozas H, Kolodner RD. The Saccharomyces cerevisiae MLH3 gene functions in AlSH3-dependent suppression of frameshift mutations. Proc Nad Acad Sei USA 1998;9S: 12404-9.
-
(1998)
Proc Nad Acad Sei USA
, vol.9
, pp. 12404-12409
-
-
Flores-Rozas, H.1
Kolodner, R.D.2
-
65
-
-
0032519335
-
The Escherichia coli MutL protein stimulates binding of Vsr and MutS to heteroduplex DNA
-
Drotschmann K, Aronshtam A, Fritz HJ, Marinus MG. The Escherichia coli MutL protein stimulates binding of Vsr and MutS to heteroduplex DNA. Nucleic Acids Res 1998;26:948-53.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 948-953
-
-
Drotschmann, K.1
Aronshtam, A.2
Fritz, H.J.3
Marinus, M.G.4
-
66
-
-
0033591855
-
Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer-Implications for clinical predisposition testing
-
Syngal S, Fox EA, Li C, et al. Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer-Implications for clinical predisposition testing. JAMA 1999;2S2:247-53.
-
(1999)
JAMA
, vol.22
, pp. 247-253
-
-
Syngal, S.1
Fox, E.A.2
Li, C.3
-
67
-
-
0033054250
-
Excision repair invades the territory of mismatch repair
-
Sancar A. Excision repair invades the territory of mismatch repair. Nat Genet 1999;21:247-9.
-
(1999)
Nat Genet
, vol.21
, pp. 247-249
-
-
Sancar, A.1
-
68
-
-
10344228783
-
Altered expression of hMSH2 and hMLH I in tumors with microsatellite instability' and genetic alterations in mismatch repair genes
-
Thibodeau SN, French AJ, Roche PC, et al. Altered expression of hMSH2 and hMLH I in tumors with microsatellite instability' and genetic alterations in mismatch repair genes. Cancer Res 1996;56:4836-!0.
-
(1996)
Cancer Res
, vol.56
, pp. 4836
-
-
Thibodeau, S.N.1
French, A.J.2
Roche, P.C.3
-
69
-
-
0028072991
-
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
-
Herman JG, Latif F, Veng Y, et al. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc Nail Acad Sei USA 1994;91:9700-.
-
(1994)
Proc Nail Acad Sei USA
, vol.91
, pp. 9700
-
-
Herman, J.G.1
Latif, F.2
Veng, Y.3
-
70
-
-
0028845142
-
Inactivation of the CDKN2/pl6/MTSl gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman JG, Merlo A, Mao L, et al. Inactivation of the CDKN2/pl6/MTSl gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 1995;55:4525-30.
-
(1995)
Cancer Res
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
-
71
-
-
0029011539
-
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor pl6/CDKN2/MTS1 in human cancers
-
Merlo A, Herman JG, Mao L, et al. 5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor pl6/CDKN2/MTS1 in human cancers. NatMcd 1995;l:686-92.
-
(1995)
NatMcd
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
-
73
-
-
0030812206
-
Association benveen CpG island methylation and microsatellite instability in colorectal cancer
-
Ahuja N, Mohan AL, Li Q, et al. Association benveen CpG island methylation and microsatellite instability in colorectal cancer. Cancer Res 1997;57: 3370-4.
-
(1997)
Cancer Res
, vol.57
, pp. 3370-3374
-
-
Ahuja, N.1
Mohan, A.L.2
Li, Q.3
-
74
-
-
0031017268
-
Methylation of the hMLHl promoter correlates with lack of expression of hMLHl in sporadic colon tumors and mismatch repair-defective human tumor cell lines
-
Kane IMF, Loda M, Gaida GM, et al. Methylation of the hMLHl promoter correlates with lack of expression of hMLHl in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 1997;57: 808-11.
-
(1997)
Cancer Res
, vol.57
, pp. 808-811
-
-
Imf, K.1
Loda, M.2
Gaida, G.M.3
-
75
-
-
13144266670
-
Incidence and functional consequences of hMLHl promoter hypermethylation in colorectal carcinoma
-
Herman JG, Umar A, Polyak K, et al. Incidence and functional consequences of hMLHl promoter hypermethylation in colorectal carcinoma. ProcKail Acad Sei USA 199S;95:6870-5.
-
ProcKail Acad Sei USA 199S
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
-
76
-
-
13144307115
-
Biallelic inactivation of hMLHl by epigenetic gene silencing, a novel mechanism causing human MSI cancers
-
Veigl ML, Kasturi L, Olechnowicz J, et al. Biallelic inactivation of hMLHl by epigenetic gene silencing, a novel mechanism causing human MSI cancers. Proc Nad Acad Sei USA 1998;95:8698-702.
-
(1998)
Proc Nad Acad Sei USA
, vol.95
, pp. 8698-8702
-
-
Veigl, M.L.1
Kasturi, L.2
Olechnowicz, J.3
-
77
-
-
0032146118
-
Hypermethylation of the hMLHl promoter in colon cancer with microsatellite instability
-
Cunningham JM, Christensen ER, Tester DJ, et al. Hypermethylation of the hMLHl promoter in colon cancer with microsatellite instability. Cancer Res 199S;5S:3455-60.
-
Cancer Res 199S
, vol.5
, pp. 3455-3460
-
-
Cunningham, J.M.1
Christensen, E.R.2
Tester, D.J.3
-
78
-
-
0033621170
-
Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: The predominant role of hMLHl
-
Wheeler JMD, Beck NE, Kim HC, Tomlinson IPM, Mortensen NJM, Bodmer WF. Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLHl. Proc Natl AcadSciUSA 1999;96:10296-301.
-
(1999)
Proc Natl AcadSciUSA
, vol.96
, pp. 10296-10301
-
-
Jmd, W.1
Beck, N.E.2
Kim, H.C.3
Ipm, T.4
Njm, M.5
Bodmer, W.F.6
-
79
-
-
0032997736
-
MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers
-
Simpkins SB, Bocker T, Svvisher EM, et al. MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers. Hum Mol Genet 1999;S:661-6.
-
(1999)
Hum Mol Genet
, pp. 661-666
-
-
Simpkins, S.B.1
Bocker, T.2
Svvisher, E.M.3
-
80
-
-
0001119305
-
MLHl promoter methylation and lack of hMLHl expression in sporadic gastric carcinomas with high-frequency microsatellite instability
-
Leung SY, Yuen ST, Chung LP, Chu KM, Chan AS, Ho JC. hMLHl promoter methylation and lack of hMLHl expression in sporadic gastric carcinomas with high-frequency microsatellite instability. Cancer Res 1999;59: 159-64.
-
(1999)
Cancer Res
, vol.59
, pp. 159-164
-
-
Leung, S.Y.1
Yuen, S.T.2
Chung, L.P.3
Chu, K.M.4
Chan, A.S.5
-
81
-
-
0030746884
-
Spl binding is inhibited by (m)Cp(m)CpG methylation
-
Clark SJ, Harrison J, Molloy PL. Spl binding is inhibited by (m)Cp(m)CpG methylation. Gene 1997;195:67-71.
-
(1997)
Gene
, vol.195
, pp. 67-71
-
-
Clark, S.J.1
Harrison, J.2
Molloy, P.L.3
-
82
-
-
0025981310
-
Methylation-sensitive sequence-specific DN'A binding by the c-Myc basic region
-
Prendergast GC, Ziff EB. Methylation-sensitive sequence-specific DN'A binding by the c-Myc basic region. Science 1991;251:186-9.
-
(1991)
Science
, vol.251
, pp. 186-189
-
-
Prendergast, G.C.1
Ziff, E.B.2
-
83
-
-
0032960181
-
Cancer epigenetics comes of age
-
Jones PA, Laird PW. Cancer epigenetics comes of age. Nat Genet 1999;21:163-7.
-
(1999)
Nat Genet
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
84
-
-
0031860739
-
Cloning and characterization of a family of novel mammalian DN'A (cytosine-5) methyltransferases
-
Okano M, Xie S, Li E. Cloning and characterization of a family of novel mammalian DN'A (cytosine-5) methyltransferases (letter). Nat Genet 1998; 19:219-20.
-
(1998)
Nat Genet
, vol.19
, pp. 219-220
-
-
Okano, M.1
Xie, S.2
Li, E.3
-
85
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
-
Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 1999;21:103-7.
-
(1999)
Nat Genet
, vol.21
, pp. 103-107
-
-
Cameron, E.E.1
Bachman, K.E.2
Myohanen, S.3
Herman, J.G.4
Baylin, S.B.5
-
86
-
-
33744577304
-
Inheritance of susceptibility to cancer in man
-
Bodmer WF. Inheritance of susceptibility to cancer in man. Cancer Surv 1982;1:1-18.
-
(1982)
Cancer Surv
, vol.1
, pp. 1-18
-
-
Bodmer, W.F.1
-
88
-
-
0010945939
-
APC mutations in colorectal tumors with mismatch repair deficiency
-
Huang J, Papadopoulos N, McKinley AJ, et al. APC mutations in colorectal tumors with mismatch repair deficiency. Proc Nail Acad Sei USA 1996;93: 9049-54.
-
(1996)
Proc Nail Acad Sei USA
, vol.93
, pp. 9049-9054
-
-
Huang, J.1
Papadopoulos, N.2
McKinley, A.J.3
-
89
-
-
0031908348
-
Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours
-
Homfray TF, Cottrell SE, Ilyas M, et al. Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours. Hum Mutât 1998; 11:114-20.
-
(1998)
Hum Mutât
, vol.11
, pp. 114-120
-
-
Homfray, T.F.1
Cottrell, S.E.2
Ilyas, M.3
-
90
-
-
0027452417
-
Genomic instability occurs in colorectal carcinomas but not in adenomas
-
Young J, Leggett B, Gustafson C, et al. Genomic instability occurs in colorectal carcinomas but not in adenomas. Hum Mutât 1993;2:351-4.
-
(1993)
Hum Mutât
, vol.2
, pp. 351-354
-
-
Young, J.1
Leggett, B.2
Gustafson, C.3
-
92
-
-
0028124528
-
-
Lane DP. p53 and human cancers. BrMedBull 1994;50:582-9.
-
(1994)
BrMedBull
, vol.50
, pp. 582-589
-
-
Cancers, H.1
-
93
-
-
0028803770
-
Failure of programmed cell death and differentiation as causes of tumors: Some simple mathematical models
-
Tomlinson IP, Bodmer WF. Failure of programmed cell death and differentiation as causes of tumors: some simple mathematical models. Proc Natl Acad Sci USA 1995;92:11130-1.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11130-11131
-
-
Tomlinson, I.P.1
Bodmer, W.F.2
-
94
-
-
0033168064
-
Apoptosis induced by overexpression ofhMSH2 or hMUïl
-
Zhang H, Richards B, Wilson T, et al. Apoptosis induced by overexpression ofhMSH2 or hMUïl. Cancer Res 1999;59:3021-7.
-
(1999)
Cancer Res
, vol.59
, pp. 3021-3027
-
-
Zhang, H.1
Richards, B.2
Wilson, T.3
-
95
-
-
0032514366
-
Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53
-
Eshleman JR, Casey G, Kochera ME, et al. Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53. Oncogens 1998; 17:719-25.
-
(1998)
Oncogens
, vol.17
, pp. 719-725
-
-
Eshleman, J.R.1
Casey, G.2
Kochera, M.E.3
-
96
-
-
0033011006
-
Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog
-
Tomlinson I, Bodmer W. Selection, the mutation rate and cancer: ensuring that the tail does not wag the dog. NatMed 1999;5:11-12.
-
(1999)
NatMed
, vol.5
, pp. 11-12
-
-
Tomlinson, I.1
Bodmer, W.2
-
97
-
-
0033126113
-
Runme Shaw Memorial Lecture: Somatic evolution of cancer
-
Bodmer WF. 1998 Runme Shaw Memorial Lecture: Somatic evolution of cancer. Ann AcadMcd Singapore 1999;28:323-9.
-
(1999)
Ann AcadMcd Singapore
, vol.28
, pp. 323-329
-
-
-
98
-
-
0029267352
-
Immune surveillance in colorectal carcinoma
-
Branch P, Bicknell DC, Rowan A, Bodmer WF, Karran P. Immune surveillance in colorectal carcinoma (letter). Nat Genet 1995;9:231-2.
-
(1995)
Nat Genet
, vol.9
, pp. 231-232
-
-
Branch, P.1
Bicknell, D.C.2
Rowan, A.3
Bodmer, W.F.4
Karran, P.5
-
99
-
-
0032546360
-
Mutations of mitotic checkpoint genes in human cancers
-
Cahill DP, Lengauer C, Yu J, et al. Mutations of mitotic checkpoint genes in human cancers. Nature 1998;392:300-3.
-
(1998)
Nature
, vol.392
, pp. 300-303
-
-
Cahill, D.P.1
Lengauer, C.2
Yu, J.3
-
100
-
-
0029066689
-
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
-
Markowitz S, VangJ, Myeroff L, et a!. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science 1995;26S:1336-8.
-
(1995)
Science
, vol.26
, pp. 1336-1338
-
-
Markowitz, S.1
Vang, J.2
Myeroff, L.3
-
101
-
-
16144368515
-
Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours
-
Souza RF, Appel R, Yin J, et al. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours (letter). Nat Genet 1996;14:255-7.
-
(1996)
Nat Genet
, vol.14
, pp. 255-257
-
-
Souza, R.F.1
Appel, R.2
Yin, J.3
-
102
-
-
0031018674
-
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
-
Rampino N, Yamamoto H, lonov Y, et al. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science 1997;21S:967-9.
-
(1997)
Science
, vol.21
, pp. 967-969
-
-
Rampino, N.1
Yamamoto, H.2
Lonov, Y.3
-
103
-
-
0027943743
-
Pathology of hereditary non-polyposis colorectal cancer
-
Jass JR, Smyrk TC, Stewart SM, Lane MR, Lanspa SJ, Lynch HT. Pathology of hereditary non-polyposis colorectal cancer. Anticancer Res 1994;14: 1631-4.
-
(1994)
Anticancer Res
, vol.14
, pp. 1631-1634
-
-
Jass, J.R.1
Smyrk, T.C.2
Stewart, S.M.3
Lane, M.R.4
Lanspa, S.J.5
Lynch, H.T.6
-
104
-
-
7144256236
-
Morphology of sporadic colorectal cancer with DN'A replication errors
-
Jass JR, Do KA, Simms LA, et al. Morphology of sporadic colorectal cancer with DN'A replication errors. Gut 1998;42:673-9.
-
(1998)
Gut
, vol.42
, pp. 673-679
-
-
Jass, J.R.1
Do, K.A.2
Simms, L.A.3
-
105
-
-
0343399664
-
Poorly differentiated colonie adenocarcinoma, medullary type: Clinical, phenotypic, and molecular characteristics
-
Ruschoff J, Dietmaier W, Luttges J, et al. Poorly differentiated colonie adenocarcinoma, medullary type: clinical, phenotypic, and molecular characteristics. Am JPaihol 1997; 150:1815-25.
-
(1997)
Am JPaihol
, vol.150
, pp. 1815-1825
-
-
Ruschoff, J.1
Dietmaier, W.2
Luttges, J.3
-
106
-
-
0031809108
-
Diagnosis of hereditary non-polyposis colorectal cancer
-
Jass Diagnosis of hereditary non-polyposis colorectal cancer. Histopathologund;y 1998;32:49I-7.
-
(1998)
Histopathologund;y
, vol.32
-
-
Jass, J.R.1
-
107
-
-
0028559212
-
Unicryptal loss of heterozygosity in hereditary non-polyposis colorectal cancer
-
Jass JR, Edgar S. Unicryptal loss of heterozygosity in hereditary non-polyposis colorectal cancer. Pathology 1994;26:414-7.
-
(1994)
Pathology
, vol.26
, pp. 414-417
-
-
Jass, J.R.1
Edgar, S.2
-
108
-
-
0029089040
-
Colorectal adenomas in surgical specimens from subjects with hereditary non-polyposis colorectal cancer
-
Jass Colorectal adenomas in surgical specimens from subjects with hereditary non-polyposis colorectal cancer. Hiaopaihology 1995;27:263-7.
-
(1995)
Hiaopaihology
, vol.27
, pp. 263-267
-
-
Jass, J.R.1
-
109
-
-
0030054532
-
Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer
-
Konishi M, Kikuchi-Yanoshita R, Tanaka K, et al. Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer. Gastroenlerology 1996;11I:307-I7.
-
(1996)
Gastroenlerology
, vol.11
-
-
Konishi, M.1
Kikuchi-Yanoshita, R.2
Tanaka, K.3
|