Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 20, 1998, Pages 11915-11920

  Deweese, Theodore L ^a   Shipman, Jennifer M ^a   Larrier, Nicole A ^a   Buckley, Nicola M ^a   Kidd, Lacreis R ^b   Groopman, John D ^b   Cutler, Richard G ^c   Te Riele, Hein ^d   Nelson, William G ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b The Johns Hopkins University   (United States)

^c Genox Corporation   (United States)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Apoptosis; DNA mismatch repair; Ionizing radiation; Mutagenesis; Oxidative DNA damage

Indexed keywords

ALLELISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER RISK; DNA DAMAGE; EMBRYO; EMBRYO DEVELOPMENT; IONIZING RADIATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PREVALENCE; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION INJURY;

ALLELES; ANIMALS; APOPTOSIS; CELL LINE; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; HETEROZYGOTE; HUMANS; MICE; MUTATION; MUTS HOMOLOG 2 PROTEIN; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS; STEM CELLS; THIOGUANINE;

EID: 0032578544     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.20.11915     Document Type: Article

References (50)

1. Kinzler, K. W. & Vogelstein, B. (1996) Cell 87, 159-170.
2. Lynch, H. T., Smyrk, T. & Lynch, J. F. (1996) Int. J. Cancer 69, 38-43.
3. Leach, F. S., Nicolaides, N. C., Papadopoulos, N., Liu, B., Jen, J., Parsons, R., Peltomaki, P., Sistonen, P., Aaltonen, L. A., Nystrom-Lahti, M., et al. (1993) Cell 75, 1215-1225.
4. Bronner, C. E., Baker, S. M., Morrison, P. T., Warren, G., Smith, L. G., Lescoe, M. K., Kane, M., Earabino, C., Lipford, J., Lindblom, A., et al. (1994) Nature (London) 368, 258-261.
5. Nicolaides, N. C., Papadopoulos, N., Liu, B., Wei, Y.-F., Carter, K.-C., Ruben, S. M., Rosen, C. A., Haseltine, W. A., Fleischmann, R. D., Fraser, C. M., et al. (1994) Nature (London) 371, 75-80.
6. Ionov, Y., Peinado, M. A., Malkhosyan, S., Shibata, D. & Perucho, M. (1993) Nature (London) 363, 558-561.
7. Thihodeau, S. N., Bren, G. & Schaid, D. (1993) Science 260, 816-819.
8. Aaltonen, L. A., Peltomaki, P., Leach, F. S., Sistonen, P., Pylkkanen, L., Mecklin, J. P., Jarvinen, H., Powell, S. M., Jen, J., Hamilton, S. R., et al. (1993) Science 260, 812-816.
9. Lothe, R. A., Peltomaki, P., Meling, G. I., Aaltonen, L. A., Nystrom-Lahti, M., Pylkkanen, L., Heimdal, K., Andersen, T. I., Moller, P., Rognum, T. O., et al. (1993) Cancer Res. 53, 5849-5852.
10. Hemminki, A., Peltomaki, P., Mecklin, J.-P., Jarvinen, H., Salovaara, R., Nystrom-Lahti, M., de la Chapelle, A. & Aaltonen, L. A. (1994) Nat. Genet. 8, 405-410.
11. Papadopoulos, N., Nicolaides, N. C., Wei, Y.-F., Ruben, S. M., Carter, K. C., Rosen, C. A., Haseltine, W. A., Fleischmann, R. D., Fraser, C. M., Adams, M. D., et al. (1994) Science 263, 1625-1629.
12. Parsons, R., Li, G.-M., Longley, M. J., Modrich, P., Liu, B., Berk, T., Hamilton, S. R., Kinzler, K. W. & Vogelstein, B. (1995) Science 268, 738-740.
13. Giovannucci, E. & Willen, W. C. (1994) Ann. Med. 26, 443-452.
14. Ames, B. N., Gold, L. S. & Willett, W. C. (1995) Proc. Natl. Acad. Sci. USA 92, 5258-5265.
15. Branch, P., Aquilina, G., Bignami, M. & Karran, P. (1993) Nature (London) 362, 652-654.
16. Kat, A., Thilly, W. G., Fang, W. H., Longley, M. J., Li, G. M. & Modrich, P. (1993) Proc. Natl. Acad. Sci USA 90, 6424-6428.
17. Koi, M., Umar, A., Chauhan, D. P., Cherian, S. P., Carethers, J. M., Kunkel, T. A. & Boland, C. R. (1994) Cancer Res. 54, 4308-4312.
18. de Wind, N., Dekker, M., Berns, A., Radman, M. & te Riele, H. (1995) Cell 82, 321-330.
19. Reitmair, A. H., Risley, R., Bristow, R. G., Wilson, T., Ganesh, A., Jang, A., Peacock, J., Benchimol, S., Hill, R. P., Mak, T. W., et al. (1997) Cancer Res. 57, 3765-3771.
20. Fritzell, J. A., Narayanan, L., Baker, S. M., Bronner, C. E., Andrew, S. E., Prolla, T. A., Bradley, A., Jirik, F. R., Liskay, R. M. & Glazer, P. M. (1997) Cancer Res. 57, 5143-5147.
21. Mellon, I., Rajpal, D. K., Koi, M., Boland C. R. & Champe, G. N. (1996) Science 272, 557-560.
22. Prescott, S. M. & White, R. L. (1996) Cell 87, 783-786.
23. Eberhart, C. E., Coffey, R. J., Radhika, A., Giardiello, F. M., Ferrenbach, S. & DuBois, R. N. (1994) Gastroenterology 107, 1183-1188.
24. Giardiello, F. M., Hamilton, S. R., Krush, A. J., Piantadosi, S., Hylind, L. M., Celano, P., Booker, S. V., Robinson, C. R. & Offerhaus, G. J. (1993) N. Engl. J. Med. 328, 1313-1316.
25. Oshima, M., Dinchuk, J. E., Kargman, S. L., Oshima, H., Hancock, B., Kwong, E., Trzaskos, J. M., Evans, J. F. & Taketo, M. M. (1996) Cell 87, 803-809.
26. Ames, B. N., Shigenaga, M. K. & Hagen, T. M. (1993) Proc. Natl. Acad. Sci. USA 90, 7915-7922.
27. Friedberg, E. C., Walker, G. C. & Siede, W. (1995) DNA Repair and Mutagenesis (Am. Soc. Microbiol., Washington, DC), pp. 1-58.
28. DeWeese, T. L., Walsh, J. C., Dillehay, L. E., Kessis, T. D., Hedrick, L., Cho, K. R. & Nelson, W. G. (1997) Int. J. Radiat. Oncol. Biol. Phys. 37, 145-154.
29. Gorczyca, W. J., Gong, J. & Darzynkiewicz, Z. (1993) Cancer Res. 53, 1945-1951.
30. Canman, C. E., Gilmer, T. M., Coutts, S. B. & Kastan, M. B. (1995) Genes Dev. 9, 600-611.
31. Dizdaroglu, M. (1994) Methods Enzymol. 234, 3-16.
32. Fiala, E. S., Conaway, C. C. & Mathis, J. E. (1989) Cancer Res. 49, 5518-5522.
33. Conaway, C. C., Nie, G., Hussain, N. S. & Fiala, E. S. (1991) Cancer Res. 51, 3143-3147.
34. Hartwell, L. H. & Kastan, M. B. (1994) Science 266, 1821-1828.
35. Breimer, L. H. (1988) Br. J. Cancer 57, 6-18.
36. Ward, J. F. (1995) Radiat. Res. 142, 362-368.
37. Wood, M. L., Dizdaroglu, M., Gajewski, E. & Essigmann, J. M. (1990) Biochemistry 29, 7024-7032.
38. Shibutani, S., Takeshita, M. & Grollman, A. P. (1991) Nature (London) 349, 431-434.
39. Breimer, L. H. (1990) Mol. Carcinogen. 3, 188-197.
40. de Wind, N., Dekker, M., van Rossum, A., van der Valk, M. & te Riele, H. (1998) Cancer Res. 58, 248-255.
41. Bhattacharyya, N. P., Skandalis, A., Ganesh, A., Groden, J. & Meuth, M. (1994) Proc. Natl. Acad. Sci. USA 91, 6319-6323.
42. Eshleman, J. R., Lang, E. Z., Bowerfind, G. K., Parsons, R., Vogelstein, B., Willson, J. K., Veigl, M. L., Sedwick, W. D. & Markowitz, S. D. (1995) Oncogene 10, 33-37.
43. Kolodner, R. D. (1995) Trends Biochem. Sci. 20, 397-401.
44. Duckett, D. R., Drummond, J. T., Murchie, A. I. H., Reardon, J. T., Sancar, A., Lilley, D. M. & Modrich, P. (1996) Proc. Natl. Acad. Sci. USA 93, 6443-6447.
45. Karran, P. & Bignami, M. (1992) Nucleic Acids Res. 20, 2933-2940.
46. Nelson, W. G. & Kastan, M. B. (1994) Mol. Cell. Biol. 14, 1815-1823.
47. Wang, X. W., Vermeulen, W., Coursen, J. D., Gibson, M., Lupold, S. E., Forrester, K., Xu, G., Elmore, L., Yeh, H., Hoeijmakers, J. H. & Harris, C. C. (1996) Genes Dev. 10, 1219-1232.
48. Seong, J., Suh, C. O. & Kim, G. E. (1995) Int. J. Radiat. Oncol. Biol. Phys. 33, 869-874.
49. Shibata, D., Peinado, M. A., Ionov, Y., Malkhosyan, S. & Perucho, M. (1994) Nat. Genet. 6, 273-281.
50. Markowitz, S., Wang, J., Myeroff, L., Parsons, R., Sun, L., Lutterbaugh, J., Fan, R. S., Zborowska, E., Kinzler, K. W., Vogelstein, B., Brattain, M. & Willson, J. K. V. (1995) Science 268, 1336-1338.