Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 20, 1998, Pages 11915-11920

  Deweese, Theodore L ^a   Shipman, Jennifer M ^a   Larrier, Nicole A ^a   Buckley, Nicola M ^a   Kidd, Lacreis R ^b   Groopman, John D ^b   Cutler, Richard G ^c   Te Riele, Hein ^d   Nelson, William G ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Johns Hopkins University   (United States)

^c Genox Corporation   (United States)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Apoptosis; DNA mismatch repair; Ionizing radiation; Mutagenesis; Oxidative DNA damage

Indexed keywords

ALLELISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER RISK; DNA DAMAGE; EMBRYO; EMBRYO DEVELOPMENT; IONIZING RADIATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PREVALENCE; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION INJURY;

ALLELES; ANIMALS; APOPTOSIS; CELL LINE; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; HETEROZYGOTE; HUMANS; MICE; MUTATION; MUTS HOMOLOG 2 PROTEIN; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS; STEM CELLS; THIOGUANINE;

EID: 0032578544     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.20.11915     Document Type: Article

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