The human T-cell transcription factor-4 gene: Structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines

Cancer Research

Volumn 60, Issue 14, 2000, Pages 3872-3879

  Duval, Alex ^a   Rolland, Sandra ^a   Tubacher, Emmanuel ^a   Bui, Hung ^a   Thomas, Gilles ^a   Hamelin, Richard ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

T CELL TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; COLORECTAL CANCER; DNA SEQUENCE; EXON; FRAMESHIFT MUTATION; HUMAN; HUMAN CELL; MISSENSE MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ALTERNATIVE SPLICING; BASE SEQUENCE; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; EXONS; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; OPEN READING FRAMES; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; TCF TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0034660872     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. β-catenin as oncogene: The smoking gun
2. TCF/LEF factors earn their wings
3. The yin-yang of TCF/β-catenin signaling
4. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
5. Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
6. Association of the APC gene product with β-catenin
7. Association of the APC tumor suppressor protein with catenins
8. Functional interaction of β-catenin with the transcription factor LEF-1
9. Constitutive transcriptional activation by a β-cateninTcf complex in APC-/- colon carcinoma
10. Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF
11. The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
12. Drosophila Tcf and Groucho interact to repress Wingless signaling activity
13. XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development
14. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
15. Identification of c-MYC as a target of the APC pathway
16. Frequent frameshift mutations of the TCF-4 gene in colorectal cancers with microsatellite instability
17. Four mating-type genes control sexual differentiation in the fission yeast
18. Neurospora crassa: A mating-type region
19. Identification and cloning of TCF-1, a T lymphocyte specific transcription factor containing a sequence-specific HMG box
20. Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties
21. The human T cell transcription factor-1
22. The human high mobility group (HMG)-box transcription factor TCF-1: Novel isoforms due to alternative splicing and usage of a new exon IXA
23. Consed: A graphical tool for sequence finishing
24. Basecalling of automated sequencer traces using phred. I. Accuracy assessment
25. Basecalling of automated sequencer traces using phred. II. Error probabilities
26. Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines
27. BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines
28. Computational simulation of DNA melting and its application to denaturing gradient gel electrophoresis
29. Efficient screening of p53 mutations by denaturing gradient gel electrophoresis in colorectal tumors
30. Variable mutation frequencies in coding repeats of TCF-4 and other target genes in colon, gastric and endometrial carcinoma showing microsatellite instability
31. Assignment of the TCF-4 (TCF7L2) gene to human chromosome band 10q25.3
32. Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer