Loss of DNA mismatch repair in acquired resistance to cisplatin

Cancer Research

Volumn 56, Issue 13, 1996, Pages 3087-3090

  Aebi, Stefan ^a   Kurdi Haidar, Buran ^a   Gordon, Robert ^a   Cenni, Bruno ^a   Zheng, Hua ^a   Fink, Daniel ^a   Christen, Randolph D ^a   Boland, C Richard ^a   Koi, Minoru ^b   Fishel, Richard ^c   Howell, Stephen B ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; MICROSATELLITE DNA; NITROSOGUANIDINE; TIOGUANINE;

ARTICLE; BASE MISPAIRING; CHROMOSOME 2; CHROMOSOME 3; COLON CANCER; CONTROLLED STUDY; DNA REPAIR; DRUG CYTOTOXICITY; DRUG RESISTANCE; ENDOMETRIUM CANCER; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; OVARY ADENOCARCINOMA; PRIORITY JOURNAL;

ADENOCARCINOMA; BASE SEQUENCE; CARCINOGENS; CARRIER PROTEINS; CISPLATIN; DNA REPAIR; DNA, NEOPLASM; DNA-BINDING PROTEINS; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; IMMUNOBLOTTING; METHYLNITRONITROSOGUANIDINE; MOLECULAR SEQUENCE DATA; MUTATION; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; OVARIAN NEOPLASMS; PROTO-ONCOGENE PROTEINS; TUMOR CELLS, CULTURED;

EID: 8944230189     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Eastman, A. Characterization of the adducts produced in DNA by cis-diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum. Biochemistry, 22: 3927-3933, 1983.
2. Bradley, L. J , Yarema, K. J., Lippard, S. J., and Essigmann, J M. Mutagenicity and genotoxicity of the major DNA adduct of the antitumor drug cis-diamminedichloroplatinum(II). Biochemistry, 32: 982-988, 1993.
3. Cariello, N. F., Swenberg, J. A., and Skopek, T. R. In vitro mutational specificity of cisplatin in the human hypoxanthine guanine phosphoribosyltransferase gene. Cancer Res , 52: 2866-2873, 1992
4. Perera, F. P., Motzer, R. J., Tang, D., Reed, E., Parker, R., Warburton, D., O'Neill, P., Albertini, R., Bigbee, W. L., Jensen, R. H , Samella, R., Tsai, W-Y., Simon-Cereijido, G., Randall, C., and Bosl, G. Multiple biological markers in germ cell tumor patients treated with platinum-based chemotherapy. Cancer Res., 52: 3558-3565, 1992.
5. Fishel, R., and Kolodner, R. D. Identification of mismatch repair genes and their role in the development of cancer. Curr. Opin. Genet Dev., 5: 382-395, 1995
6. Merlo, A., Mabry, M., Gabrielson, E , Vollmer, R., Baylin, S. B., and Sidransky, D. Frequent microsatellite instability in primary small cell lung cancer. Cancer Res., 54: 2098-2101, 1994.
7. Huddart, R. A., Wooster, R., Horwich, A., and Cooper, C. S. Microsatellite instability in human testicular germ cell tumours. Br. J. Cancer, 72: 642-645, 1995.
8. King, B L , Carcangiu, M. L., Carter, D., Kiechle, M., Pfisterer, J., Pfleiderer, A., and Kacinski, B. M. Microsatellite instability in ovarian neoplasms. Br. J. Cancer, 72: 376-382, 1995.
9. Fong, K. M., Zimmerman, P V., and Smith, P. J. Microsatellite instability and other molecular abnormalities in non-small cell lung cancer. Cancer Res , 55: 28-30, 1995.
10. Thibodeau, S. N., Bren, G., and Schaid, D. Microsatellite instability in cancer of the proximal colon Science (Washington DC), 260: 816-819, 1993.
11. Aaltonen, L. A., Peltomaki, P., Leach, F. S., Sistonen, P., Pylkkanen, L , Mecklin, J. P., Jarvinen, H., Powell, S. M., Jen, J., Hamilton, S. R., Petersen, G. M , Kinzler, K. W., Vogelstein, B., and de la Chapelle, A. Clues to the pathogenesis of familial colorectal cancer. Science (Washington DC), 260. 812-816, 1993.
12. Bhattacharyya, N. P., Skandalis, A., Ganesh, A., Groden, J., and Meuth, M Mutator phenotypes in human colorectal carcinoma cell lines. Proc. Natl. Acad. Sci USA, 91: 6319-6323, 1994.
13. Markowitz, S., Wing, J., Myeroff, L , Parsons, R., Sun, L , Lutterbaugh, J., Fan, R. S., Zborowska, E., Kinzler, K W., Vogelstein, B., Brattain, M , and Willson, J. K V. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability Science (Washington DC), 268: 1336-1338, 1995
14. Kat, A , Thilly, W. G., Fang, W H., Longley, M. J., Li, G M , and Modrich, P. An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc. Natl. Acad Sci. USA, 90 6424-6428, 1993.
15. Aquilina, G , Biondo, R., Dogliotti, E , and Bignami, M. Genetic consequences of tolerance to methylation DNA damage in mammalian cells. Carcinogenesis (Lond.), 14 2097-2103, 1993.
16. Griffin, S., Branch, P , Xu, Y Z., and Karran, P. DNA mismatch binding and incision at modified guanine bases by extracts of mammalian cells: implications for tolerance to DNA methylation damage Biochemistry, 33: 4787-4793, 1994.
17. 6-alkyl guanine, incorporated 6-thioguanine and UV photoproducts. Mutat. Res , 274: 225-235, 1992
18. Disaia, P. J., Sinkovics, J. G., Rutledge, F. N , and Smith, J. P. Cell-mediated immunity to human malignant cells Am J. Obstet Gynecol., 114: 979-989, 1972.
19. Naredi, P , Heath, D D , Enns, R. E., and Howell, S. B Cross-resistance between cisplatin, antimony potassium tartrate, and arsenite in human tumor cells. J. Clin. Invest., 95: 1193-1198, 1995
20. Andrews, P. A., Murphy, M. P., and Howell, S. B. Differential potentiation of alkylating and platinating agent toxicity in human ovarian carcinoma cells by glutathione depletion. Cancer Res., 43: 6250-6253, 1985.
21. Koi, M , Umar, A., Chauhan, D P., Cherian, S P , Carethers, J. M., Kunkel, T A., and Boland, C R. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. Cancer Res., 54: 4308-4312, 1994
22. Umar, A., Boyer, J. C., Thomas, D. C., Nguyen, D C., Risinger, J. I., Boyd, J., Ionov, Y., Perucho, M., and Kunkel, T. A. Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. J. Biol Chem., 269: 14367-14370, 1994.
23. Skehan, P., Storeng, R., Scudiero, D , Monks, A , McMahon, J., Vistica, D , Warren, J. T , Bokesch, H , Kenney, S., and Boyd, M. R. New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl. Cancer Inst., 82: 1107-1112, 1990.
24. Monks, A., Scudiero, D., Skehan, P., Shoemaker, R., Paull, K., Vistica, D., Hose, C., Langley, J , Cronise, P , Vaigro-Wolff, A , Gray-Woodrich, M., Campbell, H., Mayo, J., and Boyd, M. Feasibility of a high flux anticancer drug screen using a diverse panel of cultured human tumor cell line. J Natl. Cancer Inst., 83: 757-766, 1990
25. Luria, S E., and Delbrück, M. Mutations of bacteria from virus sensitivity to virus resistance. Genetics, 28: 491-511, 1943.
26. Rossman, T. G., Goncharova, E. I., and Nadas, A. Modeling and measurement of the spontaneous mutation rate in mammalian cells. Mutat. Res., 328: 21-30, 1995.
27. Kendal, W. S., and Frost, P Pitfalls and practice of Luria-Delbrück fluctuation analysis: a review. Cancer Res., 48: 1060-1065, 1988.
28. Anderson, L. A., Friedman, L , Osborne-Lawrence, S., Lynch, E., Wetssenbach, J , Bowcock, A., and King, M. C. High density genetic map of the BRCA1 region of chromosome 17q12-q21 Genomics, 17: 618-623, 1993.
29. 2 cell cycle checkpoint Cancer Res., 55: 3721-3725, 1995.
30. Aquilina, G., Hess, P., Branch, P., MacGeoch, C., Casciano, I., Karran, P , and Bignami, M. A mismatch recognition defect in colon carcinoma confers DNA microsatellite instability and a mutator phenotype. Proc. Natl. Acad. Sci. USA, 91: 8905-8909, 1994.
31. Aquilina, G., Hess, P., Fiumicino, S., Ceccotti, S., and Bignami, M. A mutator phenotype characterizes one of two complementation groups in human cells tolerant to methylation damage. Cancer Res., 55: 2569-2575, 1995.
32. Andrews, P A., Jones, J. A., Varki, N M., and Howell, S. B. Rapid emergence of acquired cis-dichlorodiammineplatinum(II) resistance in an in vivo model of human ovarian carcinoma. Cancer Commun., 2: 93-100, 1990
33. Branch, P., Aquilina, G., Bignami, M., and Karran, P. Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage. Nature (Lond ), 362: 652-654, 1993.
34. Pan, B F , Priebe, T. S., and Nelson, J A. Mechanisms of resistance to 6-thioguanine in a murine pancreatic tumor. Cancer Chemother. Pharmacol., 29: 471-474, 1992.
35. Yen, Y., Grill, S. P , Dutschman, G. E , Chang, C. N., Zhou, B. S., and Cheng, Y. C Characterization of a hydroxyurea-resistant human KB cell line with supersensitivity to 6-thioguanine Cancer Res., 54: 3686-3691, 1994.
36. Anthoney, A , and Brown, R. The detection of genomic instability in drug resistant human tumor cell lines Proc Am. Assoc. Cancer Res., 36: 323, 1995.
37. Karran, P., and Stephenson, C. Mismatch binding proteins and tolerance to alkylating agents in human cells Mutat. Res., 236: 269-275, 1990.
38. Zhukovskaya, N., Branch, P., Aquilma, G., and Karran, P DNA replication arrest and tolerance to DNA methylation damage Carcinogenesis (Lond.), 15: 2189-2194, 1994.
39. Branch, P , Hampson, R., and Karran, P DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines. Cancer Res., 55 2304-2309, 1995.
40. de Wind, N., Dekker, M., Berns, A., Radman, M., and te Riele, H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell, 82: 321-330, 1995.