-
1
-
-
0026355962
-
Mechanisms and biological effects of mismatch repair
-
1 Modrich P. Mechanisms and biological effects of mismatch repair. Annu Rev Genet 1991;25:229-53.
-
(1991)
Annu Rev Genet
, vol.25
, pp. 229-253
-
-
Modrich, P.1
-
3
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
-
3 Ionov Y, Peinado MA, Malkhosyan S, et al. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993; 363:558-61.
-
(1993)
Nature
, vol.363
, pp. 558-561
-
-
Ionov, Y.1
Peinado, M.A.2
Malkhosyan, S.3
-
4
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
4 Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993;260:816-19.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
5
-
-
0027263363
-
Genetic mapping of a locus predisposing to human colorectal cancer
-
5 Peltomaki P, Aaltonen LA, Sistonen P, et al. Genetic mapping of a locus predisposing to human colorectal cancer. Science 1993;260:810-12.
-
(1993)
Science
, vol.260
, pp. 810-812
-
-
Peltomaki, P.1
Aaltonen, L.A.2
Sistonen, P.3
-
6
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
6 Fishel R, Lescoe MK, Rao MR, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993;75:1027-38.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.3
-
7
-
-
0027933070
-
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
-
7 Nicolaides NC, Papadopoulos N, Liu B, et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 1994;371:75-80.
-
(1994)
Nature
, vol.371
, pp. 75-80
-
-
Nicolaides, N.C.1
Papadopoulos, N.2
Liu, B.3
-
8
-
-
0028350601
-
Mutation of a mutl homolog in hereditary colon cancer
-
8 Papadopoulos N, Nicolaides NC, Wei YF, et al. Mutation of a mutL homolog in hereditary colon cancer. Science 1994; 263:1625-9.
-
(1994)
Science
, vol.263
, pp. 1625-1629
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Wei, Y.F.3
-
9
-
-
0029069972
-
Mutations of GTBP in genetically unstable cells
-
9 Papadopoulos N, Nicolaides NC, Liu B, et al. Mutations of GTBP in genetically unstable cells. Science 1995;268:1915-17.
-
(1995)
Science
, vol.268
, pp. 1915-1917
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Liu, B.3
-
10
-
-
0028900589
-
Screening reduces colorectal cancer rate in families with hereditary nonpolyposis colorectal cancer
-
10 Jarvinen HJ, Mecklin JP, Sistonen P. Screening reduces colorectal cancer rate in families with hereditary nonpolyposis colorectal cancer. Gastroenterology 1995;108:1405-11.
-
(1995)
Gastroenterology
, vol.108
, pp. 1405-1411
-
-
Jarvinen, H.J.1
Mecklin, J.P.2
Sistonen, P.3
-
11
-
-
0030061148
-
Better survival rates in patients with MLH1-associated hereditary colorectal cancer
-
11 Sankila R, Aaltonen LA, Jarvinen HJ, et al. Better survival rates in patients with MLH1-associated hereditary colorectal cancer. Gastroenterology 1996;110:682-7.
-
(1996)
Gastroenterology
, vol.110
, pp. 682-687
-
-
Sankila, R.1
Aaltonen, L.A.2
Jarvinen, H.J.3
-
12
-
-
0031968649
-
Prognosis of colorectal cancer varies in different high-risk conditions
-
12 Aarnio M, Mustonen H, Mecklin JP, et al. Prognosis of colorectal cancer varies in different high-risk conditions. Ann Med 1998;30:75-80.
-
(1998)
Ann Med
, vol.30
, pp. 75-80
-
-
Aarnio, M.1
Mustonen, H.2
Mecklin, J.P.3
-
13
-
-
0028276666
-
Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
-
13 Kim H, Jen J, Vogelstein B, et al. Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am J Pathol 1994;145:148-56.
-
(1994)
Am J Pathol
, vol.145
, pp. 148-156
-
-
Kim, H.1
Jen, J.2
Vogelstein, B.3
-
14
-
-
0030465095
-
Microsatellite instability is associated with the histological features of the tumor in nonfamilial colorectal cancer
-
14 Risio M, Reato G, di Celle PF, et al. Microsatellite instability is associated with the histological features of the tumor in nonfamilial colorectal cancer. Cancer Res 1996;56:5470-4.
-
(1996)
Cancer Res
, vol.56
, pp. 5470-5474
-
-
Risio, M.1
Reato, G.2
Di Celle, P.F.3
-
15
-
-
0032522658
-
Microsatellite instability in colorectal cancer: Different mutator phenotypes and the principal involvement of hMLH1
-
15 Thibodeau SN, French AJ, Cunningham JM, et al. Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. Cancer Res 1998;58:1713-18.
-
(1998)
Cancer Res
, vol.58
, pp. 1713-1718
-
-
Thibodeau, S.N.1
French, A.J.2
Cunningham, J.M.3
-
16
-
-
13144307115
-
Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
-
16 Veigl ML, Kasturi L, Olechnowicz J, et al. Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers. Proc Natl Acad Sci USA 1998;95:8698-702.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8698-8702
-
-
Veigl, M.L.1
Kasturi, L.2
Olechnowicz, J.3
-
17
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
17 Herman JG, Umar A, Polyak K, et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 1998;95:6870-5.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
-
18
-
-
0032146118
-
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability
-
18 Cunningham JM, Christensen ER, Tester DJ, et al. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. Cancer Res 1998;58: 3455-60.
-
(1998)
Cancer Res
, vol.58
, pp. 3455-3460
-
-
Cunningham, J.M.1
Christensen, E.R.2
Tester, D.J.3
-
19
-
-
0027136828
-
Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history
-
19 Lothe RA, Peltomaki P, Meling GI, et al. Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history. Cancer Res 1993;53:5849-52.
-
(1993)
Cancer Res
, vol.53
, pp. 5849-5852
-
-
Lothe, R.A.1
Peltomaki, P.2
Meling, G.I.3
-
20
-
-
0029991682
-
Microsatellite instability and the role of hMSH2 in sporadic colorectal cancer
-
20 Bubb VJ, Curtis LJ, Cunningham C, et al. Microsatellite instability and the role of hMSH2 in sporadic colorectal cancer. Oncogene 1996;12:2641-9.
-
(1996)
Oncogene
, vol.12
, pp. 2641-2649
-
-
Bubb, V.J.1
Curtis, L.J.2
Cunningham, C.3
-
21
-
-
0031860840
-
Incidence of DNA replication errors in patients with multiple primary cancers
-
21 Brown SR, Finan PJ, Hall NR, et al. Incidence of DNA replication errors in patients with multiple primary cancers. Dis Colon Rectum 1998;41:765-9.
-
(1998)
Dis Colon Rectum
, vol.41
, pp. 765-769
-
-
Brown, S.R.1
Finan, P.J.2
Hall, N.R.3
-
22
-
-
0032789079
-
Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair
-
22 Cawkwell L, Gray S, Murgatroyd H, et al. Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair. Gut 1999;45:409-15.
-
(1999)
Gut
, vol.45
, pp. 409-415
-
-
Cawkwell, L.1
Gray, S.2
Murgatroyd, H.3
-
23
-
-
0033523204
-
Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers
-
23 Halling KC, French AJ, McDonnell SK, et al. Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers. J Natl Cancer Inst 1999;91:1295-303.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1295-1303
-
-
Halling, K.C.1
French, A.J.2
McDonnell, S.K.3
-
24
-
-
0033036918
-
Prognostic significance of microsatellite instability in sporadic mucinous colorectal cancers
-
24 Messerini L, Ciantelli M, Baglioni S, et al. Prognostic significance of microsatellite instability in sporadic mucinous colorectal cancers. Hum Pathol 1999;30:629-34.
-
(1999)
Hum Pathol
, vol.30
, pp. 629-634
-
-
Messerini, L.1
Ciantelli, M.2
Baglioni, S.3
-
25
-
-
0032867362
-
Microsatellite instability in sporadic colorectal cancer is not an independent prognostic factor
-
25 Salahshor S, Kressner U, Fischer H, et al. Microsatellite instability in sporadic colorectal cancer is not an independent prognostic factor. Br J Cancer 1999;81:190-3.
-
(1999)
Br J Cancer
, vol.81
, pp. 190-193
-
-
Salahshor, S.1
Kressner, U.2
Fischer, H.3
-
26
-
-
0032892831
-
Microsatellite instability in sporadic colorectal carcinoma is not an indicator of prognosis
-
26 Feeley KM, Fullard JF, Heneghan MA, et al. Microsatellite instability in sporadic colorectal carcinoma is not an indicator of prognosis. J Pathol 1999;188:14-17.
-
(1999)
J Pathol
, vol.188
, pp. 14-17
-
-
Feeley, K.M.1
Fullard, J.F.2
Heneghan, M.A.3
-
27
-
-
0034105428
-
Replication error phenotype, clinicopathological variables, and patient outcome in Dukes' B stage II (T3,N0,M0) colorectal cancer
-
27 Curran B, Lenehan K, Mulcahy H, et al. Replication error phenotype, clinicopathological variables, and patient outcome in Dukes' B stage II (T3,N0,M0) colorectal cancer. Gut 2000;46:200-4.
-
(2000)
Gut
, vol.46
, pp. 200-204
-
-
Curran, B.1
Lenehan, K.2
Mulcahy, H.3
-
28
-
-
0033083214
-
Microsatellite instability: Impact on cancer progression in proximal and distal colorectal cancers
-
28 Jernvall P, Makinen MJ, Karttunen TJ, et al. Microsatellite instability: impact on cancer progression in proximal and distal colorectal cancers. Eur J Cancer 1999;35:197-201.
-
(1999)
Eur J Cancer
, vol.35
, pp. 197-201
-
-
Jernvall, P.1
Makinen, M.J.2
Karttunen, T.J.3
-
29
-
-
0033135963
-
The significance of microsateilite instability in predicting the development of metachronous multiple colorectal carcinomas in patients with nonfamilial colorectal carcinoma
-
29 Masubuchi S, Konishi F, Togashi K, et al. The significance of microsateilite instability in predicting the development of metachronous multiple colorectal carcinomas in patients with nonfamilial colorectal carcinoma. Cancer 1999;85: 1917-24.
-
(1999)
Cancer
, vol.85
, pp. 1917-1924
-
-
Masubuchi, S.1
Konishi, F.2
Togashi, K.3
-
30
-
-
0030878195
-
Genetic instability in patients with metachronous colorectal cancers
-
30 Sengupta SB, Yiu CY, Boulos PB, et al. Genetic instability in patients with metachronous colorectal cancers. Br J Surg 1997;84:996-1000.
-
(1997)
Br J Surg
, vol.84
, pp. 996-1000
-
-
Sengupta, S.B.1
Yiu, C.Y.2
Boulos, P.B.3
-
31
-
-
0032993145
-
Mismatch repair proficiency and in vitro response to 5-fluorouracil
-
31 Carethers JM, Chauhan DP, Fink D, et al. Mismatch repair proficiency and in vitro response to 5-fluorouracil. Gastroenterology 1999;117:123-31.
-
(1999)
Gastroenterology
, vol.117
, pp. 123-131
-
-
Carethers, J.M.1
Chauhan, D.P.2
Fink, D.3
-
32
-
-
0032956375
-
Mismatch repair deficiency is associated with resistance to DNA minor groove alkylating agents
-
32 Colella G, Matchini S, Di M, et al. Mismatch repair deficiency is associated with resistance to DNA minor groove alkylating agents. Br J Cancer 1999;80:338-43.
-
(1999)
Br J Cancer
, vol.80
, pp. 338-343
-
-
Colella, G.1
Matchini, S.2
Di, M.3
-
33
-
-
0031906084
-
The role of DNA mismatch repair in drug resistance
-
33 Fink D, Aebi S, Howell SB. The role of DNA mismatch repair in drug resistance. Clin Cancer Res 1998;4:1-6.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1-6
-
-
Fink, D.1
Aebi, S.2
Howell, S.B.3
-
34
-
-
0000441155
-
DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: A mild mutator pathway for colorectal cancer?
-
34 Iino H, Jass JR, Simms LA, et al. DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer? J Clin Pathol 1999;52:5-9.
-
(1999)
J Clin Pathol
, vol.52
, pp. 5-9
-
-
Iino, H.1
Jass, J.R.2
Simms, L.A.3
-
38
-
-
0029954795
-
Assessment of invasive growth pattern and lymphocytic infiltration in colorectal cancer
-
38 Jass JR, Ajioka Y, Allen JP, et al. Assessment of invasive growth pattern and lymphocytic infiltration in colorectal cancer. Histopathology 1996;28:543-8.
-
(1996)
Histopathology
, vol.28
, pp. 543-548
-
-
Jass, J.R.1
Ajioka, Y.2
Allen, J.P.3
-
39
-
-
0032534069
-
A national cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
-
39 Boland CR, Thibodeau SN, Hamilton SR, et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58: 5248-57.
-
(1998)
Cancer Res
, vol.58
, pp. 5248-5257
-
-
Boland, C.R.1
Thibodeau, S.N.2
Hamilton, S.R.3
-
40
-
-
0031877635
-
Restriction endonuclease-mediated selective polymerase chain reaction: A novel assay for the detection of K-ras mutations in clinical samples
-
40 Ward RL, Hawkins NJ, O'Grady R, et al. Restriction endonuclease-mediated selective polymerase chain reaction: a novel assay for the detection of K-ras mutations in clinical samples. Am J Pathol 1998;153:373-9.
-
(1998)
Am J Pathol
, vol.153
, pp. 373-379
-
-
Ward, R.L.1
Hawkins, N.J.2
O'Grady, R.3
-
41
-
-
0030889919
-
Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis
-
41 Ward RL, Todd AV, Santiago F, et al. Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis. Cancer 1997;79:1106-13.
-
(1997)
Cancer
, vol.79
, pp. 1106-1113
-
-
Ward, R.L.1
Todd, A.V.2
Santiago, F.3
-
42
-
-
0033055150
-
Microsatellite instability - A useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: A study in different groups of patients with colorectal cancer
-
42 Lamberti C, Kruse R, Ruelfs C, et al. Microsatellite instability - a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with colorectal cancer. Gut 1999;44:839-43.
-
(1999)
Gut
, vol.44
, pp. 839-843
-
-
Lamberti, C.1
Kruse, R.2
Ruelfs, C.3
-
43
-
-
0028915223
-
Genetic instability occurs in the majority of young patients with colorectal cancer
-
43 Liu B, Farrington SM, Petersen GM, et al. Genetic instability occurs in the majority of young patients with colorectal cancer. Nat Med 1995;1:348-52.
-
(1995)
Nat Med
, vol.1
, pp. 348-352
-
-
Liu, B.1
Farrington, S.M.2
Petersen, G.M.3
-
44
-
-
0031891134
-
Prognostic significance of DNA replication errors in young patients with colorectal cancer
-
44 Lukish JR, Muro K, DeNobile J, et al. Prognostic significance of DNA replication errors in young patients with colorectal cancer. Ann Surg 1998;227:51-6.
-
(1998)
Ann Surg
, vol.227
, pp. 51-56
-
-
Lukish, J.R.1
Muro, K.2
DeNobile, J.3
-
45
-
-
0034642605
-
Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
-
45 Gryfe R, Kim H, Hsieh ET, et al. Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. N Engl J Med 2000;342:69-77.
-
(2000)
N Engl J Med
, vol.342
, pp. 69-77
-
-
Gryfe, R.1
Kim, H.2
Hsieh, E.T.3
-
46
-
-
0031710654
-
Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences
-
46 Fujiwara T, Stolker JM, Watanabe T, et al. Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences. Am J Pathol 1998;153:1063-78.
-
(1998)
Am J Pathol
, vol.153
, pp. 1063-1078
-
-
Fujiwara, T.1
Stolker, J.M.2
Watanabe, T.3
-
47
-
-
0030778613
-
Diagnostic microsatellite instability: Definition and correlation with mismatch repair protein expression
-
47 Dietmaier W, Wallinger S, Bocker T, et al. Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression. Cancer Res 1997;57:4749-56.
-
(1997)
Cancer Res
, vol.57
, pp. 4749-4756
-
-
Dietmaier, W.1
Wallinger, S.2
Bocker, T.3
-
48
-
-
0033831989
-
Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer
-
48 Wright CM, Dent OF, Barker M, et al. Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer. Br J Surg 2000;87:1197-202.
-
(2000)
Br J Surg
, vol.87
, pp. 1197-1202
-
-
Wright, C.M.1
Dent, O.F.2
Barker, M.3
-
49
-
-
7144256236
-
Morphology of sporadic colorectal cancer with DNA replication errors
-
49 Jass JR, Do KA, Simms LA, et al. Morphology of sporadic colorectal cancer with DNA replication errors. Gut 1998;42:673-9.
-
(1998)
Gut
, vol.42
, pp. 673-679
-
-
Jass, J.R.1
Do, K.A.2
Simms, L.A.3
-
50
-
-
10344228783
-
Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes
-
50 Thibodeau SN, French AJ, Roche PC, et al. Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. Cancer Res 1996;56:4836-40.
-
(1996)
Cancer Res
, vol.56
, pp. 4836-4840
-
-
Thibodeau, S.N.1
French, A.J.2
Roche, P.C.3
-
51
-
-
17444395546
-
Unbalanced germ-line expression of hMLH1 and hMSH2 alleles in hereditary nonpolyposis colorectal cancer
-
51 Curia MC, Palmirotta R, Aceto G, et al. Unbalanced germ-line expression of hMLH1 and hMSH2 alleles in hereditary nonpolyposis colorectal cancer. Cancer Res 1999;59:3570-5.
-
(1999)
Cancer Res
, vol.59
, pp. 3570-3575
-
-
Curia, M.C.1
Palmirotta, R.2
Aceto, G.3
-
52
-
-
0030870631
-
Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred
-
52 Akiyama Y, Sato H, Yamada T, et al. Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred. Cancer Res 1997;57:3920-3.
-
(1997)
Cancer Res
, vol.57
, pp. 3920-3923
-
-
Akiyama, Y.1
Sato, H.2
Yamada, T.3
-
53
-
-
0033373180
-
Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines
-
53 Ku JL, Yoon KA, Kim DY, et al. Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines. Eur J Cancer 1999;35:1724-9.
-
(1999)
Eur J Cancer
, vol.35
, pp. 1724-1729
-
-
Ku, J.L.1
Yoon, K.A.2
Kim, D.Y.3
|