Natural substrates of the proteasome and their recognition by the ubiquitin system

Current Topics in Microbiology and Immunology

Volumn 268, Issue , 2002, Pages 137-174

  Ulrich, H D ^a  

^a M P Inst Terrestrial Microbiol   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; DNA BINDING PROTEIN; LIGASE; MEMBRANE PROTEIN; PROTEASOME; STEM CELL FACTOR; TRANSCRIPTION FACTOR; UBIQUITIN;

CELL CYCLE; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; EUKARYOTE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; REVIEW;

EUKARYOTA;

EID: 0036092435     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-59414-4_6     Document Type: Review

References (226)

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116. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
117. The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome
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119. In vitro ubiquitination of cyclin D1 by ROC1-CUL1 and ROC1-CUL3
120. A novel human WD protein, h-bTrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif
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122. A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4
123. E2/E3-mediated assembly of lysine 29-linked polyubiquitin chains
124. The abundance of cell cycle regulatory protein Cdc4p is controlled by interactions between its F box and Skp1p
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130. A complex of mammalian Ufd1 and Np14 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways
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163. Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis
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169. Are there multiple proteolytic pathways contributing to c-Fos, c-Jun and p53 protein degradation in vivo?
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171. Does this have a familiar RING?
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186. Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells
187. F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
188. Grr1 and Rbx1
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191. Signal-induced ubiquitination of IkBa by the F-box protein Slimb/b-TrCP
192. + channel deleted in Liddle's syndrome
193. Structure of the VHL-ElonginC-ElonginB complex: Implications for VHL tumor suppressor function
194. The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis
195. Structure and function of the WW domain
196. A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation
197. The ligation systems for ubiquitin and ubiquitin-like proteins
198. PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism
199. Recognition of the polyubiquitin proteolytic signal
200. Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome
201. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
202. Ubiquitin-dependent c-jun degradation in vivo is mediated by the d domain
203. p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27
204. Proteolysis and the cell cycle: With this RING I do thee destroy
205. Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair
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208. The N-end rule pathway of protein degradation
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210. Functional domains of the Rsp5 ubiquitin-protein ligase
211. Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma
212. HRD gene dependence of endoplasmic reticulum-associated degradation
213. Regulation of ubiquitin-dependent processes by deubiquitinating enzymes
214. The SCF b-TrCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkBa and b-catenin and stimulates IkBa ubiquitination in vitro
215. The E2-E3 interaction in the N-end rule pathway: The RING-H2 finger of E3 is required for the synthesis of multiubiquitin chains
216. Physical association of ubiquitin ligases and the 26S proteasome
217. Cdc28-mediated control of Cln3 cyclin degradation
218. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
219. Identification of the receptor component of the IkBa-ubiquitin ligase
220. The PY-motif of Bull protein is essential for growth of Saccharomyces cerevisiae under various stress conditions
221. Bull, a new protein that binds to the Rsp5 ubiquitin ligase in Saccharomyces cerevisiae
222. Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7
223. Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex
224. Mass spectrometric analysis of the anaphase-promoting complex from yeast: Identification of a subunit related to cullins
225. New subunits of the anaphase promoting complex of Saccharomyces cerevisiae
226. Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases