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Volumn 254, Issue 3, 1998, Pages 643-649

The ubiquitin-protein ligase E6-associated protein (E6-AP) serves as its own substrate

Author keywords

(E6 AP); Degradation; Ubiquitin; Ubiquitin protein ligase

Indexed keywords

UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

EID: 0032525905     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2540643.x     Document Type: Article
Times cited : (101)

References (32)
  • 1
    • 0028018268 scopus 로고
    • The ubiquitin-proteasome proteolylic pathway
    • Ciechanover, A. (1994) The ubiquitin-proteasome proteolylic pathway, Cell 79, 13-21.
    • (1994) Cell , vol.79 , pp. 13-21
    • Ciechanover, A.1
  • 2
    • 0029162583 scopus 로고
    • Selective protein degradation: A journey's end within the proteasome
    • Jentsch, S. & Schlenker, S. (1995) Selective protein degradation: a journey's end within the proteasome, Cell 82, 881-884.
    • (1995) Cell , vol.82 , pp. 881-884
    • Jentsch, S.1    Schlenker, S.2
  • 3
    • 0030457014 scopus 로고    scopus 로고
    • Ubiquitin-dependent protein degradation
    • Hochstrasser, M. (1996), Ubiquitin-dependent protein degradation, Annu. Rev. Genet. 30, 405-439.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 405-439
    • Hochstrasser, M.1
  • 4
    • 0029805901 scopus 로고    scopus 로고
    • Role of the ubiquitin/ proteasome system in regulated protein degradation in Saccharomyces cerevisiae
    • Smith, S. E., Koegl, M. & Jentsch, S. (1996) Role of the ubiquitin/ proteasome system in regulated protein degradation in Saccharomyces cerevisiae. Biol. Chem. Hoppe Seyler 377, 437-446.
    • (1996) Biol. Chem. Hoppe Seyler , vol.377 , pp. 437-446
    • Smith, S.E.1    Koegl, M.2    Jentsch, S.3
  • 5
  • 6
    • 0030054178 scopus 로고    scopus 로고
    • Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis
    • Hieke, L. & Riezman, H. (1996) Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis, Cell 84, 277-287.
    • (1996) Cell , vol.84 , pp. 277-287
    • Hieke, L.1    Riezman, H.2
  • 7
    • 0030881952 scopus 로고    scopus 로고
    • Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein
    • Galan, J. & Haguenauer-Tsapis, R. (1997) Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein, EMBO J. 16, 5847-5854.
    • (1997) EMBO J. , vol.16 , pp. 5847-5854
    • Galan, J.1    Haguenauer-Tsapis, R.2
  • 8
    • 0028898424 scopus 로고
    • Protein ubiquitination involving an E1- E2-E3 enzyme ubiquitin thioester cascade
    • Scheffner, M., Nuher, U. & Huibregtse, J. M. (1995) Protein ubiquitination involving an E1- E2-E3 enzyme ubiquitin thioester cascade, Nature 373, 81-83.
    • (1995) Nature , vol.373 , pp. 81-83
    • Scheffner, M.1    Nuher, U.2    Huibregtse, J.M.3
  • 9
    • 0025050840 scopus 로고
    • The recognition component of the N-end rule pathway
    • Bartel, B., Wünning, I. & Varshavsky, A. (1990) The recognition component of the N-end rule pathway, EMBO J. 9, 3179-3189.
    • (1990) EMBO J. , vol.9 , pp. 3179-3189
    • Bartel, B.1    Wünning, I.2    Varshavsky, A.3
  • 10
    • 0030337875 scopus 로고    scopus 로고
    • Mechanisms and regulation of ubiquitin-mediated cyclin degradation
    • Hershko, A. (1996) Mechanisms and regulation of ubiquitin-mediated cyclin degradation. Adv. Exp. Med. Biol. 389, 221-227.
    • (1996) Adv. Exp. Med. Biol. , vol.389 , pp. 221-227
    • Hershko, A.1
  • 12
    • 0030662523 scopus 로고    scopus 로고
    • F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
    • Skowyra, D., Craig, K. L., Tyers, M., Elledge, S. J. & Harper, J. W. (1997) F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex, Cell 91, 209-219.
    • (1997) Cell , vol.91 , pp. 209-219
    • Skowyra, D.1    Craig, K.L.2    Tyers, M.3    Elledge, S.J.4    Harper, J.W.5
  • 13
    • 0030695025 scopus 로고    scopus 로고
    • A complex of Cdc4p, Skp1p. and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
    • Feldman, R. M., Corell, C. C., Kaplan, K. B. & Deshaies, R. J. (1997) A complex of Cdc4p, Skp1p. and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p, Cell 91, 221-230.
    • (1997) Cell , vol.91 , pp. 221-230
    • Feldman, R.M.1    Corell, C.C.2    Kaplan, K.B.3    Deshaies, R.J.4
  • 14
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner, M., Huibregtse, J. M., Vierstra, R. D. & Howley, P. M. (1993) The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53, Cell 75, 495-505.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 15
    • 0029036701 scopus 로고
    • A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
    • Huibregtse, J. M., Scheffner, M., Beaudenon, S. & Howley, P. M. (1995) A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase, Proc. Natl Acad. Sci. USA 92, 2563-2567.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 2563-2567
    • Huibregtse, J.M.1    Scheffner, M.2    Beaudenon, S.3    Howley, P.M.4
  • 16
    • 0025932933 scopus 로고
    • A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18
    • Huibregste, J. M., Scheffner, M. & Howley, P. M. (1991) A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J. 13, 4129-4135.
    • (1991) EMBO J. , vol.13 , pp. 4129-4135
    • Huibregste, J.M.1    Scheffner, M.2    Howley, P.M.3
  • 17
    • 0027396829 scopus 로고
    • Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53
    • Huibregste, J. M., Scheffner. M. & Howley, P. M. (1993) Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol. Cell. Biol. 13, 775-784.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 775-784
    • Huibregste, J.M.1    Scheffner, M.2    Howley, P.M.3
  • 18
    • 0028971506 scopus 로고
    • NPI1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase
    • Hein, C., Springael, J.-Y., Volland, C., Haguenauer-Tsapis, R. & André, B. (1995) NPI1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase. Mol. Microbiol. 18, 77-87.
    • (1995) Mol. Microbiol. , vol.18 , pp. 77-87
    • Hein, C.1    Springael, J.-Y.2    Volland, C.3    Haguenauer-Tsapis, R.4    André, B.5
  • 19
    • 0030888109 scopus 로고    scopus 로고
    • The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase
    • Huibregtse, J. M., Yang, J. C. & Beaudenon, S. L. (1997) The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase. Proc. Natl Acad. Sci. USA 94, 3656-3661.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 3656-3661
    • Huibregtse, J.M.1    Yang, J.C.2    Beaudenon, S.L.3
  • 20
    • 0030006130 scopus 로고    scopus 로고
    • Pub1 acts as an E6-AP-like protein ubiquitin ligase in the degradation of cdc25
    • Nefsky, B. & Beach, D. (1996) Pub1 acts as an E6-AP-like protein ubiquitin ligase in the degradation of cdc25, EMBO J. 15, 1301-1312.
    • (1996) EMBO J. , vol.15 , pp. 1301-1312
    • Nefsky, B.1    Beach, D.2
  • 21
    • 0031012849 scopus 로고    scopus 로고
    • UBE3A/E6-AP mutations cause Angelman syndrome
    • Kishino, T., Lalande, M. & Wagstaff, J. (1997) UBE3A/E6-AP mutations cause Angelman syndrome, Nat. Genet. 15, 70-73.
    • (1997) Nat. Genet. , vol.15 , pp. 70-73
    • Kishino, T.1    Lalande, M.2    Wagstaff, J.3
  • 24
    • 0030908874 scopus 로고    scopus 로고
    • Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperatives
    • Kumar, S., Kao, W. H. & Howley, P. M. (1997) Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperatives, J. Biol. Chem. 272, 13548-13554.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13548-13554
    • Kumar, S.1    Kao, W.H.2    Howley, P.M.3
  • 25
    • 0025271203 scopus 로고
    • Association of human papillomavirus types 16 and 18 E6 proteins with p53
    • Werness, B. A., Levine, A. J. & Howley, P. M. (1990) Association of human papillomavirus types 16 and 18 E6 proteins with p53, Science 248, 76-79.
    • (1990) Science , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 26
    • 0027169680 scopus 로고
    • Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins
    • Huibregtse, J. M. Scheffner, M. & Howley, P. M. (1993) Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins, Mol. Cell. Biol. 13, 4918-4927.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4918-4927
    • Huibregtse, J.M.1    Scheffner, M.2    Howley, P.M.3
  • 27
    • 0026769411 scopus 로고
    • Multiple forms of ubiquitin-activating enzyme E1 from wheat. Identification of an essential cysteine by in vitro mutagenesis
    • Hatfield, P. M. & Vierstra, R. D. (1992) Multiple forms of ubiquitin-activating enzyme E1 from wheat. Identification of an essential cysteine by in vitro mutagenesis, J. Biol. Chem. 267, 14799-14803.
    • (1992) J. Biol. Chem. , vol.267 , pp. 14799-14803
    • Hatfield, P.M.1    Vierstra, R.D.2
  • 28
    • 0028607435 scopus 로고
    • Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53
    • Scheffner, M., Huibregtse, J. M. & Howley, P. M. (1994) Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53. Proc. Natl Acad. Sci. USA 91, 8797-8801.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 8797-8801
    • Scheffner, M.1    Huibregtse, J.M.2    Howley, P.M.3
  • 29
    • 0030043724 scopus 로고    scopus 로고
    • Cloning human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5
    • Nuber, U., Schwarz, S., Kaiser, P., Schneider, R. & Scheffner, M. (1996) Cloning human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5. J. Biol. Chem. 271, 2795-2800.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2795-2800
    • Nuber, U.1    Schwarz, S.2    Kaiser, P.3    Schneider, R.4    Scheffner, M.5
  • 30
    • 0023802469 scopus 로고
    • The resolution and characterization of putative ubiquitin carrier protein isozymes from rabbit reticulocytes
    • Haas, A. L. & Bright, P. M. (1988) The resolution and characterization of putative ubiquitin carrier protein isozymes from rabbit reticulocytes, J Biol. Chem. 263, 13258-13267.
    • (1988) J Biol. Chem. , vol.263 , pp. 13258-13267
    • Haas, A.L.1    Bright, P.M.2
  • 31
    • 0031569842 scopus 로고    scopus 로고
    • The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing
    • Yamamoto, Y., Huibregtse, J. M. & Howley, P. M. (1997) The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing. Genomics 41, 263-266.
    • (1997) Genomics , vol.41 , pp. 263-266
    • Yamamoto, Y.1    Huibregtse, J.M.2    Howley, P.M.3
  • 32
    • 0029870836 scopus 로고    scopus 로고
    • Protein degradation or regulation: Ub the judge
    • Hochstrasser, M. (1996) Protein degradation or regulation: Ub the judge. Cell 84, 813-815.
    • (1996) Cell , vol.84 , pp. 813-815
    • Hochstrasser, M.1


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