A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae

Journal of Cell Biology

Volumn 145, Issue 6, 1999, Pages 1199-1208

  Fisk, Harold A ^a   Yaffe, Michael P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cytoskeleton; Mitochondria; Organelle inheritance; Ubiquitin; Yeast

Indexed keywords

ARGININE; INTERMEDIATE FILAMENT PROTEIN; LYSINE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACHROMOSOMAL INHERITANCE; FUNGUS GROWTH; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS; TEMPERATURE SENSITIVITY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SUBSTITUTION; CARRIER PROTEINS; CELL CYCLE PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION; GENES, ESSENTIAL; GENES, FUNGAL; GENES, SUPPRESSOR; GENETIC COMPLEMENTATION TEST; LIGASES; MITOCHONDRIA; MUTATION; PHENOTYPE; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUPPRESSION, GENETIC; TEMPERATURE; UBIQUITIN-PROTEIN LIGASE COMPLEXES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0033553857     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.145.6.1199     Document Type: Article

References (51)

1. Adams, A.E.M., and D. Botstein. 1989. Dominant suppressors of yeast actin mutations that are reciprocally suppressed. Genetics. 121:675-683.
2. Adams, A.E.M., D. Botstein, and D.G. Drubin. 1989. A yeast actin-binding protein is encoded by SAC6, a gene found by suppression of an actin mutation. Science. 243:231-233.
3. Altschul, S.F., W. Gish, W. Miller, E.W. Myers, and D.J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
4. Arnason, T., and M.J. Ellison. 1994. Stress resistance in Saccharomyces cerevisiae is strongly correlated with assembly of a novel type of multiubiquitinated chain. Mol. Cell. Biol. 14:7876-7883.
5. Attardi, G., and G. Schatz. 1988. Biogenesis of mitochondria. Annu. Rev. Cell Biol. 4:289-333.
6. Berger, K.H., and M.P. Yaffe. 1996. Mitochondrial distribution and inheritance. Experientia. 52:1111-1116.
7. Berger, K.H., and M.P. Yaffe. 1998. Prohibitin family members interact genetically with mitochondrial inheritance components in Saccharomyces cerevisiae. Mol. Cell. Biol. 18:4043-4052.
8. Berger, K.H., L.F. Sogo, and M.P. Yaffe. 1997. Mdm12p, a component required for mitochondrial inheritance that is conserved between budding and fission yeast. J. Cell Biol. 136:545-553.
9. Broach, J.R., J.N. Strathern, and J.B. Hicks. 1979. Transformation in yeast: development of a hybrid vector and isolation of the CAN1 gene. Gene. 8:121-133.
10. Brodsky, J.L., and A.A. McCracken. 1997. ER-associated and proteosome-mediated protein degradation: how two topologically restricted events came together. Trends Cell Biol. 7:151-156.
11. Burgess, S.M., M. Delannoy, and R.E. Jensen. 1994. MMMI encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria. J. Cell Biol. 126:1375-1391.
12. Crane, D.I., J.E. Kalish, and S.J. Gould. 1994. The Pichia pastoris PAS4 gene encodes a ubiquitin-conjugating enzyme required for peroxisome assembly. J. Biol. Chem. 269:21835-21844.
13. Ellison, M.J., and M. Hochstrasser. 1991. Epitope-tagged ubiquitin. A new probe for analyzing ubiquitin function. J. Biol. chem. 266:21150-21157.
14. Fisk, H.A., and M.P. Yaffe. 1997. Mutational analysis of Mdm1p function in nuclear and mitochondrial inheritance. J. Cell Biol. 138:485-494.
15. Gatan, J.M., and R. Haguenauer-Tsapis. 1997. Ubiquitin Lys63 is involved in ubiquitination of a yeast plasma membrane protein. EMBO (Eur. Mol. Biol. Org.) J. 16:5847-5854.
16. Galan, J.M., V. Moreau, B. Andre, C. Volland, and R. Haguennauer-Tsapis. 1996. Ubiquitination mediated by the Npilp/Rsp5p ubiquitin-protein ligase is required for endocytosis of the yeast uracil permease. J. Biol. Chem. 271: 10946-10952.
17. Hampton, R.Y., and H. Bhakta. 1997. Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase. Proc. Natl. Acad. Sci. USA. 94: 12944-12948.
18. Hermann, G.J., E.J. King, and J.M. Shaw. 1997. The yeast gene, MDM20, is necessary for mitochondrial inheritance and organization of the actin cytoskeleton. J. Cell Biol. 137:141-153.
19. Hicke, L., and H. Riezman. 1996. Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell. 84:277-287.
20. Hochstrasser, M. 1996. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30:405-439.
21. Hochstrasser, M., M.J. Ellison, V. Chau, and A. Varshavsky. 1991. The short-lived MAT alpha 2 transcriptional regulator is ubiquitinated in vivo. Proc. Natl. Acad. Sci. USA. 88:4606-4610.
22. Huibregtse, J., M. Scheffner, S. Beaudenon, and P.M. Howley. 1995. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA. 92:2563-2567.
23. Huibregtse, J.M., M. Scheffner, and P.M. Howley. 1991. A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO (Eur. Mol. Biol. Org.) J. 10:4129-4135.
24. Huibregtse, J.M., J.C. Yang, and S.L. Beaudenon. 1997. The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA. 94:3656-3661.
25. Imhof, M.O., and D.P. McDonnell. 1996. Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors. Mol. Cell. Biol. 16:2594-2605.
26. Liakopoulos, D., G. Doenges, K. Matuschewski, and S. Jentsch. 1998. A novel protein modification pathway related to the ubiquitin system. EMBO (Eur. Mol. Biol. Org.) J. 17:2208-2214.
27. Mahajan, R., C. Delphin, T. Guan, L. Gerace, and F. Melchior. 1997. A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Cell. 88:97-107.
28. McCabe, P.C. 1990. Production of single-stranded DNA by asymmetric PCR. In PCR Protocols. M.A. Innis, D.H. Gelfand, J.J. Sninsky, and T.J. White, editors. Academic Press, San Diego, CA. 76-83.
29. McConnell, S.J., and M.P. Yaffe. 1992. Nuclear and mitochondrial inheritance in yeast depends on novel cytoplasmic structures defined by the MDM1 protein. J. Cell Biol. 118:385-395.
30. McConnell, S.J., and M.P. Yaffe. 1993. Intermediate filament formation by a yeast protein essential for organelle inheritance. Science. 260:687-689.
31. McConnell, S.J., L.C. Stewart, A. Talin, and M.P. Yaffe. 1990. Temperature-sensitive yeast mutants defective in mitochondrial inheritance. J. Cell Biol. 111:967-976.
32. Nickas, M.E., and M.P. Yaffe. 1996. BRO1, a novel gene that interacts with components of the pkc1p-mitogen-activated protein kinase pathway in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:2585-2593.
33. Orr-Weaver, T.L., W. Raymond, K. Foelich, P. Errada, N. Kleckner, D. Botstein, and M.A. Hoyt. 1983. Genetic applications of yeast transformation with linear and gapped plasmids. Methods Enzymol. 101:228-245.
34. Palade, G. 1983. Membrane biogeneis: an overview. Methods Enzymol. 96:29-40.
35. Pickart, C.M. 1997. Targeting of substrates to the 26S proteosome. FASEB (Fed. Am. Soc. Exp. Biol.) J. 11:1055-1066.
36. Rose, M.D., and J.R. Broach. 1991. Cloning genes by complementation. Methods Enzymol. 194:195-230.
37. Rose, M.D., P. Novick, J.H. Thomas, D. Botstein, and G.R. Fink. 1987. A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene. 60:237-243.
38. Rose, M.D., F. Winston, and P. Hieter. 1990. Methods in Yeast Genetics: A Laboratory Course Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
39. Seufert, W., and S. Jentsch. 1990. Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins. EMBO (Eur. Mol. Biol. Org.) J. 9:543-550.
40. Seufert, W., J.P. McGrath, and S. Jentsch. 1990. UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation. EMBO (Eur. Mol. Biol. Org.) J. 9:4535-4541.
41. Sikorski, R.S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics. 122:19-27.
42. Smith, B.J., and M.P. Yaffe. 1991. A mutation in the yeast heat-shock factor gene causes temperature-sensitive defects in both mitochondrial protein import and the cell cycle. Mol. Cell. Biol. 11:2647-2655.
43. Sogo, L.F., and M.P. Yaffe. 1994. Regulation of mitochondrial morphology and inheritance by Mdm10p, a protein of the mitochondrial outer membrane. J. Cell Biol. 126:1361-1373.
44. Springael, J.Y., and B. Andre. 1998. Nitrogen-regulated ubiquitination of the Gap1 permease of Saccharomyces cerevisiae. Mol. Biol. Cell. 9:1253-1263.
45. Stevens, B. 1981. Mitochondrial structure. In The Molecular Biology of the Yeast Saccharomyces cerevisiae. Vol. 1. J.N. Strathern, E.W. Jones, and J.R. Broach, editors. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 471-504.
46. Wiebel, F.F., and W.-H. Kunau. 1992. The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes. Nature. 359: 73-76.
47. Williamson, D.H., and D.J. Fennell. 1975. The use of fluorescent DNA-binding agent for detecting and separating yeast mitochondrial DNA. Methods Cell Biol. 12:335-351.
48. Yashiroda, H., T. Oguchi, Y. Yasuda, A. Toh-E, and Y. Kikuchi. 1996. Bull, a new protein that binds to the Rsp5 ubiquitin ligase in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:3255-3263.
49. Zhuang, Z., and R.B. McCauley. 1989. Ubiquitin is involved in the in vitro insertion of monoamino oxidase B into mitochondrial outer membranes. J. Biol. Chem. 264:14594-14596.
50. Zoladek, T., G. Vaduva, L.A. Hunter, M. Boguta, B.D. Go, N.C. Martin, and A.K. Hopper. 1995. Mutations altering the mitochondrial-cyloplasmic distribution of Mod5p implicate the actin cytoskeleton and mRNA 3′ ends and/or protein synthesis in mitochondrial delivery. Mol. Cell. Biol. 15:6884-6894.
51. Zoladek, T., A. Tobiasz, G. Vaduva, M. Boguta, N.C. Martin, and A.K. Hopper. 1997. MDP1, a Saccharomyces cerevisiae gene involved in mitochondrial/cytoplasmic protein distribution, is identical to the ubiquitin-protein ligase gene RSP5. Genetics. 145:595-603.