PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism

Cell

Volumn 90, Issue 3, 1997, Pages 459-467

  Tang, Amy H ^a   Neufeld, Thomas P ^a,b   Kwan, Elaine ^a   Rubin, Gerald M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; EMBRYO DEVELOPMENT; GENETIC TRANSCRIPTION; NERVE CELL; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR DOWN REGULATION; REPRESSOR GENE; TRANSCRIPTION REGULATION;

PHYLLOPODA;

EID: 0030849728     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80506-1     Document Type: Article

References (65)

1. Amson, R.B., Nemani, M., Roperch, J.P., Israeli, D., Bougueleret, L., Le Gall, I., Medhioub, M., Linares-Cruz, G., Lethrosne, F., Pasturaud, P., et al. (1996). Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: activation of the vertebrate homologue of the Drosophila seven in absentia gene. Proc. Natl. Acad. Sci. USA 93, 3953-3957.
2. Artavanis-Tsakonas, S., Matsuno, K., and Fortini, M.E. (1995). Notch signaling. Science 268, 225-232.
3. Basler, K., Siegrist, P.,and Hafen, E. (1989).The spatial and temporal expression pattern of sevenless is exclusively controlled by geneinternal elements. EMBO J. 8, 2381-2386.
4. Bowtell, D.D.L., Kimmel, B.E., Simon, M.A., and Rubin, G.M. (1989). Regulation of the complex pattern of sevenless expression in the developing Drosophila eye. Proc. Natl. Acad. Sci. USA 86, 6245-6249.
5. Brunner, D., Oellers, N., Szabad, J., Biggs, W.H., III, Zipursky, S.L., and Hafen, E. (1994). Again-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways. Cell 76, 875-888.
6. Brown, J.L., Sonoda, S., Ueda, H., Scott, M.P., and Wu, C. (1991). Repression of the Drosophila fushi tarazu (ftz) segmentation gene. EMBO J. 10, 665-674.
7. Brown, J.L., and Wu, C. (1993). Repression of Drosophila pair-rule segmentation genes by ectopic expression of tramtrack. Development 117, 45-58.
8. Bunch, T.A., Grinblat, Y., and Goldstein, L.S. (1988). Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells. Nucleic Acids Res. 16, 1043-1061.
9. Campos-Ortega, J.A. (1996). Numb diverts Notch pathway off the Tramtrack. Neuron 17, 1-4.
10. Carthew, R.W., and Rubin, G.M. (1990). seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye. Cell 63, 561-577.
11. Carthew, R.W., Neufeld, T.P., and Rubin, G.M. (1994). Identification of genesthat interact with the sina gene in Drosophila eye development. Proc. Natl. Acad. Sci. USA 91, 11689-11693.
12. Chang, H.C., Solomon, N.M., Wassarman, D.A., Karim, F.D., Therrien, M., Rubin, G.M., and Wolff, T. (1995). phyllopod functions in the fate determination of a subset of photoreceptors in Drosophila. Cell 80, 463-472.
13. Chien, CT., Bartel, P.L., Sternglanz, R., and Fields, S. (1991). The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad. Sci. USA 88, 9578-9582.
14. Ciechanover, A. (1994). The ubiquitin-proteasome proteolytic pathway. Cell 79, 13-21.
15. Delia, N.G., Senior, P.V., and Bowtell, D.D.L. (1993). Isolation and characterization of murine homologues of the Drosophila seven in absentia gene (sina). Development 117, 1333-1343.
16. Dickson B. (1995). Nuclear factors in Sevenless signaling. Trends Genet. 11, 106-111.
17. Dickson, B., Dominguez, M., van der Strafen, A., and Hafen, E. (1995). Control of Drosophila photoreceptor cell fates by Phyllopod, a novel nuclear protein acting downstream of the Raf kinase. Cell 80, 453-462.
18. Dickson, B., and Hafen, E. (1993). Genetic dissection of eye development in Drosophila. In The Development of Drosophila melanogaster, M. Bate and A. Martinez-Arias, eds. (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press), pp. 1327-1362.
19. Dickson, B., Sprenger, F., Morrison, D., and Hafen, E. (1992). Raf functions downstream of Ras 1 in the Sevenless signal transduction pathway. Nature 360, 600-603.
20. Estojak J., Brent R., and Golemis, E.A. (1995). Correlation of twohybrid affinity data with in vitro measurements. Mol. Cell. Biol. 15, 5820-5829.
21. Finley, R.L., Jr., and Brent, R. (1994). Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators. Proc. Natl. Acad. Sci. USA 91, 12980-12984.
22. Finley, R.L., Jr., Thomas, B.J., Zipursky, S.L., and Brent, R. (1996). Isolation of Drosophila cyclin D, a protein expressed in the morpho-genetic furrow beforeentry into S phase. Proc. Natl. Acad. Sci. USA 93, 3011-3015.
23. Fortini, M.E., Simon, M.A., and Rubin, G.M. (1992). Signaling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation. Nature 355, 559-561.
24. Golemis, E.A., Gyuris, J., and Brent, R. (1994). Two hybrid systems/ interaction traps. In Current Protocols in Molecular Biology, F.M. Ausubel, R. Brent, R. Kingston, D. Moore, J. Seidman, J.A. Smith, and K. Struhl, eds. (New York: John Wiley & Sons), pp. 13.14.1-13.14.17.
25. Guo, M., Bier, E., Jan, L.Y., and Jan, Y.N. (1995). tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the Drosophila PNS. Neuron 14, 913-925.
26. Guo, M., Jan, L.Y., and Jan, Y.N. (1996). Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron 17, 27-41.
27. Gyuris, J., Golemis, E., Chertkov, H., and Brent, R. (1993). Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75, 791-803.
28. Harrison, S.D., and Travers, A.A. (1990). The tramtrack gene encodes a Drosophila finger protein that interacts with the ftz transcriptional regulatory region and shows a novel embryonic expression pattern. EMBO J. 9, 207-216.
29. Hay, B.A., Wolff, T., and Rubin, G.M. (1994). Expression of baculovi-rus P35 prevents cell death in Drosophila. Development 120, 2121-2129.
30. Hochstrasser, M. (1995). Ubiquitin, proteasomes, and the regulation of intracellular protein degradation.Curr. Opin. Cell Biol. 7, 215-223.
31. Hochstrasser, M. (1996). Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30, 405-439
32. Huang, Y., and Fischer-Vize, J.A. (1996). Undifferentiated cells in the developing Drosophila eye influence facet assembly and require the Fat facets ubiquitin-specific protease. Development 122, 3207-3216.
33. Kauffmann, R.C., Li, S., Gallagher, P.A., Zhang, J., and Carthew, R.W. (1996). Ras1 signaling and transcriptional competence in the R7 cell of Drosophila. Genes Dev. 10, 2167-2178.
34. Kimmel, B.E., Heberlein, U., and Rubin, G.M. (1990). The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype. Genes Dev. 4, 712-727.
35. King, R.W., Peters, J.M., Tugendreich, S., Rolfe, M., Hieter, P., and Kirschner, M.W. (1995). A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81, 279-288.
36. Krasnow, M.A., Saffman, E.E., Kornfeld, K., and Hogness, D.S. (1989). Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells. Cell 16, 1031-1043.
37. Lai, Z.-C., and Rubin, G.M. (1992). Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein. Cell 70, 609-620.
38. Lai, Z.-C., Harrison, S.D., Karim, F., Li, Y., and Rubin, G.M. (1996). Loss of tramtrack gene activity results in ectopic R7 cell formation, even in a sina mutant background. Proc. Natl. Acad. Sci. USA 93, 5025-5030.
39. Marshall, C.J. (1995). Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185.
40. Musti, A.M., Treier, M., and Bohmann, D. (1997). Reduced ubiquitindependent degradation of c-Jun after phosphorylation by MAP kinases. Science 275, 400-402.
41. Nemani, M., Linares-Cruz, G., Bruzzoni-Giovanelli, H., Roperch, J.P., Tuynder, M., Bougueleret, L., Cherif, D., Medhioub, M., Pasturaud, P., Alvaro, V., et al. (1996). Activation of the human homologue of the Drosophila sina gene in apoptosisand tumor suppression. Proc. Natl. Acad. Sci. USA 93, 9039-9042.
42. O'Neill, E.M., Rebay, L.Tjian, R., and Rubin, G.M. (1994). The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell 78, 137-147.
43. Read, D., Levine, M., and Manley, J.L. (1992). Ectopic expression of the Drosophila tramtrack gene results in multiple embryonic defects, including repression of even-skipped and fushi tarazu. Mech. Dev. 38, 183-195.
44. Read, D., and Manley, J.L. (1992). Alternatively spliced transcripts of the Drosophila tramtrack gene encode zinc finger proteins with distinct DNA binding specificities. EMBO J. 11, 1035-1044.
45. Rebay, I., and Rubin, G.M. (1995). Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway. Cell 81, 857-866.
46. ∥250 interacts with RAP74: implications for RNA polymerase II initiation. Genes Dev. 9, 2747-2755.
47. Saurin. A.J., Borden, K.L.B., Boddy, M.N., and Freemont, P.S. (1996). Does this have a familiar ring? Trends Biochem. Sci. 21, 208-214.
48. Scheffner, M., Huibregtse, J.M., Vierstra, R.D., and Howley, P.M. (1993). The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75, 495-505.
49. Scheffner, M., Werness, B.A., Huibregtse, J.M., Levine, A.J., and Howley, P.M. (1990).The E6 oncoprotein encoded by human papillo-mavirus types 16 and 18 promotes the degradation of p53. Cell 63, 1129-1136.
50. Schiestl, R.H., and Gietz, R.D. (1989). High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet. 16, 339-346.
51. Spradling, A.C., and Rubin, G.M. (1982). Transposition of cloned P elements into Drosophila germ line chromosomes. Science 218, 341-347.
52. Tautz, D., and Pfeifle, C. (1989). A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.
53. Therrien, M., Michaud, N.R., Rubin, G.M., and Morrison, D.K. (1996). KSR modulates signal propagation within the MAPK cascade. Genes Dev. 10, 2684-2695.
54. Thummel, C.S., Boulet, A.M., and Lipshitz, H.D. (1988). Vectors for Drosophila P-element-mediated transformation and tissue culture transfection. Gene 74, 445-456.
55. Treier, M., Bohmann, D., and Mlodzik, M. (1995). JUN cooperates with the ETS domain protein pointed to induce photoreceptor R7 fate in the Drosophila eye. Cell 83, 753-760.
56. Treier, M., Seufert, W., and Jentsch, S. (1992). Drosophila UbcD1 encodes a highly conserved ubiquitin-conjugating enzyme involved in selective protein degradation. EMBO J. 11, 367-372.
57. van der Geer, P., Hunter, T., and Lindberg, R.A. (1994). Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell Biol. 10, 251-337.
58. Wassarman, D.A., Therrien, M., and Rubin, G.M. (1995). The Ras signaling pathway in Drosophila. Curr. Opin. Genet. Dev. 5, 44-50.
59. Wolff, T., and Ready, D.F. (1991). Cell death in normal and rough eye mutants of Drosophila. Development 113, 825-839.
60. Wolff, T., and Ready, D.F. (1993). Pattern formation in the Drosophila retina. In Developmental Biology of Drosophila, M. Bate and A. Martins-Arias, eds. (Cold Spring Harbor, NY: Cold Spring Harbor Press), pp. 1277-1325.
61. Xiong, W.C., and Montell, C. (1993). Tramtrack is a transcriptional represser required for cell fate determination in the Drosophila eye. Genes Dev. 7, 1085-1096.
62. Xu, T., and Rubin, G.M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.
63. Yamamoto, D., Nihonmatsu, I., Matsuo, T., Miyamoto, H., Kondo, S., Hirata, K., and Ikegami, Y. (1996). Genetic interactions of pokkuri with seven in absentia, tramtrack and downstream components of the sevenless pathway in R7 photoreceptor induction in Drosophila melanogaster. Roux's Arch. Dev. Biol. 205, 215-224.
64. Zervos, A.S., Gyuris, J., and Brent, R. (1993). Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell 72, 223-232.
65. Zipursky, S.L., and Rubin, G.M. (1994). Determination of neuronal cell fate: lessons from the R7 neuron of Drosophila. Annu. Rev. Neurosci. 77, 373-397.