Herpes simplex virus type 1 immediate-early protein Vmw110 inhibits progression of cells through mitosis and from G1 into S phase of the cell cycle

Journal of Virology

Volumn 73, Issue 11, 1999, Pages 9456-9467

  Lomonte, Patrick ^a   Everett, Roger D ^a  

^a INSTITUTE OF VIROLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; IMMEDIATE EARLY PROTEIN; NUCLEAR PROTEIN; VIRUS DNA;

ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CENTROMERE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DNA CONTENT; GENETIC TRANSFECTION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; METAPHASE; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; VIRUS CELL INTERACTION;

EID: 0032863957     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.11.9456-9467.1999     Document Type: Article

References (57)

1. Ace, C. I., T. A. McKee, J. M. Ryan, J. M. Cameron, and C. M. Preston. 1989. Construction and characterization of herpes simplex virus type 1 mutant unable to transinduce immediate-early gene expression. J. Virol. 63:2260-2269.
2. Ascoli, C. A., and G. G. Maul. 1991. Identification of a novel nuclear domain. J. Cell Biol. 112:785-795.
3. Bernat, R. L., G. G. Borisy, N. F. Rothchild, and W. C. Earnshaw. 1990. Injection of anti-centromere antibodies in interphase disrupts events required for chromosome movement at mitosis. J. Cell Biol. 111:1519-1533.
4. Bernat, R. L., M. R. Delannoy, N. F. Rothfield, and W. C. Earnshaw. 1991. Disruption of centromere assembly during interphase inhibits kinetochore morphogenesis and function in mitosis. Cell 66:1229-1238.
5. Cai, W., T. D. Astor, L. M. Liptak, C. Cho, D. Coen, and P. A. Schaffer. 1993. The herpes simplex virus type 1 regulatory protein ICP0 enhances replication during acute infection and reactivation from latency. J. Virol. 67:7501-7512.
6. Clements, J. B., and N. D. Stow. 1989. A herpes simplex virus type 1 mutant containing a deletion within immediate-early gene 1 is latency competent in mice. J. Gen. Virol. 70:2501-2506.
7. De Bruyn Kops, A., and D. M. Knipe. 1988. Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein. Cell 55:857-868.
8. DeLuca, N. M., M. A. Courtney, and P. A. Schaffer. 1984. Temperature-sensitive mutants in herpes simplex virus type 1 ICP4 permissive for early gene expression. J. Virol. 52:767-776.
9. Dixon, R. A. F., and P. A. Schafer. 1980. Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175. J. Virol. 36:189-203.
10. Earnshaw, W. C., and N. Rothfield. 1985. Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma. Chromosoma 91:313-321.
11. Everett, R. D. 1989. Construction and characterisation of herpes simplex virus type 1 mutants with defined lesions in immediate-early gene 1. J. Gen. Virol. 70:1185-1202.
12. Everett, R. D., C. M. Preston, and N. D. Stow. 1991. Functional and genetic analysis of the role of Vmw110 in herpes simplex virus replication, p. 50-76. In E. K. Wagner (ed.), The control of herpes simplex virus gene expression. CRC Press Inc., Boca Raton, Fla.
13. Everett, R. D., A. Cross, and A. Orr. 1993. A truncated form of herpes simplex virus type 1 immediate-early protein Vmw110 is expressed in a cell-type dependent manner. Virology 197:751-756.
14. Everett, R. D., M. R. Meredith, A. Orr, A. Cross, M. Kathoria, and J. Parkinson. 1997. A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein. EMBO J. 16:1519-1530.
15. Everett, R. D., P. Freemont, H. Saitoh, M. Dasso, A. Orr, M. Kathoria, and J. Parkinson. 1998. The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110 and proteasome-dependent loss of several PML isoforms. J. Virol. 72:6581-6591.
16. Everett, R. D., A. Orr, and C. M. Preston. 1998. A viral activator of gene expression functions via the ubiquitin-proteasome pathway. EMBO J. 17: 7161-7169.
17. Everett, R. D., W. C. Earnshaw, J. Findlay, and P. Lomonte. 1999. Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110. EMBO J. 18:1526-1538.
18. Fields, B. N., D. M. Knipe, and P. M. Howley. 1996. Virology, 3rd ed., vol. 2. Lippincott-Raven, Philadelphia, Pa.
19. Fraser, N. W., T. M. Block, and J. G. Spivack. 1992. The latency associated transcripts of herpes simplex virus: RNA in search of a function. Virology 191:1-8.
20. Harris, R. A., R. D. Everett, X. Zhu, S. Silverstein, and C. M. Preston. 1989. The herpes simplex virus (HSV) immediate-early protein VmwllO reacti-vates latent HSV type 2 in an in vitro latency system. J. Virol. 63:3513-3515.
21. Hilton, M. J., D. Mounghane, T. McLean, N. V. Contractor, J. O'Neil, K. Carpenter, and S. L. Bachenheimer. 1995. Induction by herpes simplex virus of free and heteromeric forms of E2F transcription factor. Virology 213: 624-638.
22. Hunter, T., and J. Pines. 1994. Cyclins and cancer II: cyclin D and CDK inhibitors come of age. Cell 79:573-582.
23. Johnson, P. A., A. Miyanohara, F. Levine, T. Cahill, and T. Friedmann. 1992. Cytotoxicity of a replication-defective mutant of herpes simplex virus type 1. J. Virol. 66:2952-2965.
24. Johnson, P. A., M. J. Wang, and T. Friedmann. 1994. Improved cell survival by the reduction of immediate-early gene expression in replication-defective mutants of herpes simplex virus type 1 but not by mutation of the virion host shutoff function. J. Virol. 68:6347-6362.
25. Kawaguchi, Y., R. Bruni, and B. Roizman. 1997. Interaction of herpes simplex virus 1 α regulatory protein ICP0 with elongation factor 1δ: ICP0 affects translation machinery. J. Virol. 71:1019-1024.
26. Kawaguchi, Y., C. Van Sant, and B. Roizman. 1997. Herpes simplex type 1 a regulatory protein ICP0 interacts with and stabilizes the cell cycle regulator cyclin D3. J. Virol. 71:7328-7336.
27. Larn, E. W.-F., and N. B. La Thangue. 1994. DP and E2F proteins: coordinating transcription with cell cycle progression. Curr. Opin. Cell Biol. 6:859-866.
28. La Thangue, N. B. 1994. DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control. Trends Biochem. Sei. 19:108-114.
29. Lees-Miller, S. P., M. C. Long, M. A. Kilvert, V. Larn, S. A. Rice, and C. A. Spencer. 1996. Attenuation of DNA-dependent protein kinase activity and its catalytic subunit by the herpes simplex virus type 1 transactivator ICP0. J. Virol. 70:7471-7477.
30. Leib, D. A., D. M. Coen, C. L. Bogard, K. A. Hicks, D. R. Yager, D. M. Knipe, K. L. Tyler, and P. A. Schaffer. 1989. Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. J. Virol. 63:759-768.
31. Lomonte, P., and R. D. Everett. Unpublished data.
32. McCarthy, A. M., L. McMahan, and P. A. Schaffer. 1989. Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient. J. Virol. 63:18-27.
33. Meredith, M. R., A. Orr, and R. D. Everett. 1994. Herpes simplex virus type 1 immediate-early protein VmwllO binds strongly and specifically to a 135kD cellular protein. Virology 200:457-469.
34. Parkinson, J., S. P. Lees-Miller, and R. D. Everett. 1999. Herpes simplex virus type 1 immediate-early protein Vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase. J. Virol. 73:650-657.
35. Post, L. E., and B. Roizman. 1981. A generalized technique for deletion of specific genes in large genomes: alpha gene 22 of herpes simplex virus type 1 is not essential for growth. Cell 25:227-232.
36. Preston, C. M. 1979. Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsk. J. Virol. 29:228-239.
37. Preston, C. M., and M. J. Nicholl. 1997. Repression of gene expression upon infection of cells with herpes simplex virus type 1 mutants impaired for immediate-early protein synthesis. J. Virol. 71:7807-7813.
38. Preston, C. M., R. Mabbs, and M. J. Nicholl. 1997. Construction and characterization of herpes simplex virus type 1 mutants with conditional defects in immediate early gene expression. Virology 229:228-239.
39. Rieder, C. L., and E. D. Salmon. 1998. The vertebrate cell kinetochore and its roles during mitosis. Trends Cell Biol. 8:310-318.
40. Roizman, B., and A. E. Sears. 1996. Herpes simplex viruses and their replication, p. 2231-2296. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed. Raven Press, New York, N. Y.
41. Sacks, W. R., C. C. Greene, D. P. Aschman, and P. A. Schaffer. 1985. Herpes simplex virus type 1 ICP27 is an essential regulatory protein. J. Virol. 55: 796-805.
42. Sacks, W. R., and P. A. Schaffer. 1987. Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture. J. Virol. 61:829-839.
43. Saitoh, H., J. Tomkiel, C. A. Cooke, H. Ratrie, M. Maurer, N. F. Rothfield, and W. C. Earnshaw. 1992. CENP-C, and autoantigen in scleroderma, is a component of the human inner kinetochore plate. Cell 70:115-125.
44. Samaniego, L. A., N. Wu, and N. A. DeLuca. 1997. The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27. J. Virol. 71: 4614-4625.
45. Samaniego, L. A., L. Neiderhiser, and N. A. DeLuca. 1998. Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins. J. Virol. 72:3307-3320.
46. Schang, L. M., J. Phillips, and P. A. Schaffer. 1998. Requirement for cellular cyclin-dependent kinases in herpes simplex virus replication and transcription. J. Virol. 72:5626-5637.
47. Schang, L. M., A. Rosenberg, and P. A. Schaffer. 1999. Transcription of herpes simplex virus immediate-early and early genes is inhibited by roscovitine, an inhibitor specific for cellular cyclin-dependent kinases. J. Virol. 73:2161-2172.
48. Sears, A. E., I. W. Halliburton, B. Meignier, S. Silver, and B. Roizman. 1985. Herpes simplex virus 1 mutant deleted in the α22 gene: growth and gene expression in permissive and restrictive cells and establishment of latency in mice. J. Virol. 55:338-346.
49. Sherr, C. J. 1994. G1 phase progression: cycling on cue. Cell 79:551-555.
50. Showalter, L. D., M. Zweig, and B. Hampar. 1981. Monoclonal antibodies to herpes simplex type 1 proteins including the immediate-early protein ICP4. Infect. Immun. 34:684-692.
51. Stow, N. D., and E. C. Stow. 1986. Isolation and characterisation of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate-early polypeptide Vmw110. J. Gen. Virol. 67:2571-2585.
52. Tomkiel, J., C. A. Cooke, H. Saitoh, R. Bernat, and W. C. Earnshaw. 1994. CENP-C is required for maintaining proper kinetochore size and for a timely transition to anaphase. J. Cell Biol. 125:531-545.
53. Watson, R. J., and J. B. Clements. 1978. Characterization of transcription-deficient temperature-sensitive mutants of herpes simplex virus type 1. Virology 91:364-379.
54. Weinberg, R. A. 1995. The retinoblastoma protein and cell cycle control. Cell 81:323-330.
55. Wilcox, C. L., R. L. Smith, R. D. Everett, and D. Mysofski. 1997. The herpes simplex virus type 1 immediate-early ICP0 is necessary for the efficient establishment of latent infection. J. Virol. 71:6777-6785.
56. Wu, N., S. C. Watkins, P. A. Schaffer, and N. A. DeLuca. 1996. Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22. J. Virol. 70:6358-6369.
57. Zhu, X., J. Chen, C. S. H. Young, and S. Silverstein. 1990. Reactivation of latent herpes simplex virus by adenovirus recombinants encoding mutant IE-0 gene products. J. Virol. 64:4489-4498.