Structure of an E6AP-UbcH7 complex: Insights into ubiquitination by the E2-E3 enzyme cascade

Science

Volumn 286, Issue 5443, 1999, Pages 1321-1326

  Huang, Lan ^a   Kinnucan, Elspeth ^a   Wang, Guangli ^c   Beaudenon, Sylvie ^c   Howley, Peter M ^d   Huibregtse, Jon M ^c   Pavletich, Nikola P ^a,b  

^a Cell Biochem and Biophys Program   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME STRUCTURE; GENE MUTATION; HAPPY PUPPET SYNDROME; PRIORITY JOURNAL; PROTEIN DOMAIN; UTERINE CERVIX CANCER;

AMINO ACID SEQUENCE; ANGELMAN SYNDROME; BINDING SITES; CATALYTIC DOMAIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; HUMANS; LIGASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

EID: 0032741446     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.286.5443.1321     Document Type: Article

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