-
1
-
-
0021245666
-
Bacteriophage P1 site-specific recombination. Purification and properties of the Cre recombinase protein
-
ABREMSKI, K., AND R. HOESS. Bacteriophage P1 site-specific recombination. Purification and properties of the Cre recombinase protein. J. Biol. Chem. 259: 1509-1514, 1984.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 1509-1514
-
-
Abremski, K.1
Hoess, R.2
-
2
-
-
0029877297
-
3 dopamine receptor gene is associated with hyperactivity in mice
-
3 dopamine receptor gene is associated with hyperactivity in mice. Proc. Natl. Acad. Sci. USA 93: 1945-1949, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1945-1949
-
-
Accili, D.1
Fishburn, C.S.2
Drago, J.3
Steiner, H.4
Lachowicz, J.E.5
Park, B.H.6
Gauda, E.B.7
Lee, E.J.8
Cool, M.H.9
Sibley, D.R.10
Gerfen, C.R.11
Westphal, H.12
Fuchs, S.13
-
3
-
-
0027380988
-
Normalization of auditory physiology by cigarette smoking in schizophrenic patients
-
ADLER, L. E., L. D. HOFFER, A. WISER, AND R. FREEDMAN. Normalization of auditory physiology by cigarette smoking in schizophrenic patients. Am. J. Psychiatry 150: 1856-1861, 1993.
-
(1993)
Am. J. Psychiatry
, vol.150
, pp. 1856-1861
-
-
Adler, L.E.1
Hoffer, L.D.2
Wiser, A.3
Freedman, R.4
-
4
-
-
0023551350
-
Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter
-
ADRA, C., P. BOER, AND M. McBURNEY. Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter. Gene 60: 65-74, 1987.
-
(1987)
Gene
, vol.60
, pp. 65-74
-
-
Adra, C.1
Boer, P.2
McBurney, M.3
-
5
-
-
0029932831
-
Transgenic and knockout mice in the study of neurodegenerative diseases
-
AGUZZI, A., S. BRANDNER, S. MARINO, AND J. STEINBACH. Transgenic and knockout mice in the study of neurodegenerative diseases. J. Mol. Med. 74: 111-126, 1996.
-
(1996)
J. Mol. Med.
, vol.74
, pp. 111-126
-
-
Aguzzi, A.1
Brandner, S.2
Marino, S.3
Steinbach, J.4
-
6
-
-
0028355079
-
Transgenic and knock-out mice: Models of neurological disease
-
AGUZZI, A., S. BRANDNER, U. SURE, D. RUEDI, AND S. ISENMANN. Transgenic and knock-out mice: models of neurological disease. Brain Pathol. 4: 3-20, 1994.
-
(1994)
Brain Pathol.
, vol.4
, pp. 3-20
-
-
Aguzzi, A.1
Brandner, S.2
Sure, U.3
Ruedi, D.4
Isenmann, S.5
-
7
-
-
0028139045
-
Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice
-
AIBA, A., C. CHEN, K. HERRUP, C. ROSENMUND, C. F. STEVENS, AND S. TONEGAWA. Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice. Cell 79: 365-375, 1994.
-
(1994)
Cell
, vol.79
, pp. 365-375
-
-
Aiba, A.1
Chen, C.2
Herrup, K.3
Rosenmund, C.4
Stevens, C.F.5
Tonegawa, S.6
-
8
-
-
0028149789
-
Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice
-
AIBA, A., M. KANO, C. CHEN, M. E. STANTON, G. D. FOX, K. HERRUP, T. A. ZWINGMAN, AND S. TONEGAWA. Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice. Cell 79: 377-388, 1994.
-
(1994)
Cell
, vol.79
, pp. 377-388
-
-
Aiba, A.1
Kano, M.2
Chen, C.3
Stanton, M.E.4
Fox, G.D.5
Herrup, K.6
Zwingman, T.A.7
Tonegawa, S.8
-
9
-
-
0003153048
-
Brain slice methods
-
edited by R. Dingledine. New York: Plenum
-
ALGER, B., S. DHANJAL, R. DINGLEDINE, J. GARTHWAITE, G. HENDERSON, G. KING, P. LIPTON, A. NORTH, P. SCHWARTZKROIN, T. SEARS, M. SEGAL, T. WHITTINGHAM, AND J. WILLIAMS. Brain slice methods. In: Brain Slices, edited by R. Dingledine. New York: Plenum, 1984, p. 381-437.
-
(1984)
Brain Slices
, pp. 381-437
-
-
Alger, B.1
Dhanjal, S.2
Dingledine, R.3
Garthwaite, J.4
Henderson, G.5
King, G.6
Lipton, P.7
North, A.8
Schwartzkroin, P.9
Sears, T.10
Segal, M.11
Whittingham, T.12
Williams, J.13
-
10
-
-
0023607333
-
Oxytocin acts as an antidepressant in two animal models of depression
-
ARLETTI, R., AND A. BERTOLINI. Oxytocin acts as an antidepressant in two animal models of depression. Life Sci. 41: 1725-1730, 1987.
-
(1987)
Life Sci.
, vol.41
, pp. 1725-1730
-
-
Arletti, R.1
Bertolini, A.2
-
11
-
-
0029584496
-
Trinucleotide repeat expansion and human disease
-
ASHLEY, C. T., JR., AND S. T. WARREN. Trinucleotide repeat expansion and human disease. Annu. Rev. Genet. 29: 703-728, 1995.
-
(1995)
Annu. Rev. Genet.
, vol.29
, pp. 703-728
-
-
Ashley Jr., C.T.1
Warren, S.T.2
-
12
-
-
0029013598
-
Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency
-
BACH, M. E., R. D. HAWKINS, M. OSMAN, E. R. KANDEL, AND M. MAYFORD. Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency. Cell 81: 905-915, 1995.
-
(1995)
Cell
, vol.81
, pp. 905-915
-
-
Bach, M.E.1
Hawkins, R.D.2
Osman, M.3
Kandel, E.R.4
Mayford, M.5
-
13
-
-
0029165456
-
2 receptors
-
2 receptors. Nature 377: 424-428, 1995.
-
(1995)
Nature
, vol.377
, pp. 424-428
-
-
Baik, J.H.1
Picetti, R.2
Saiardi, A.3
Thiriet, G.4
Dierich, A.5
Depaulis, A.6
Le Meur, M.7
Borrelli, E.8
-
14
-
-
0008337290
-
The pathology of the motor neuron diseases
-
edited by A. Engel and B. Banker. New York: McGraw-Hill
-
BANKER, B. The pathology of the motor neuron diseases. In: Myology, edited by A. Engel and B. Banker. New York: McGraw-Hill, 1986, p. 2031-2066.
-
(1986)
Myology
, pp. 2031-2066
-
-
Banker, B.1
-
17
-
-
0027404604
-
The molecular machinery for secretion is conserved from yeast to neurons
-
BENNETT, M. K., AND R. H. SCHELLER. The molecular machinery for secretion is conserved from yeast to neurons. Proc. Natl. Acad. Sci. USA 90: 2559-2563, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2559-2563
-
-
Bennett, M.K.1
Scheller, R.H.2
-
18
-
-
0030267396
-
Bypass of lethality with mosaic mice generated by CreloxP-mediated recombination
-
BETZ, U.A., C. A. VOSSHENRICH, K. RAJEWSKY, AND W. MULLER. Bypass of lethality with mosaic mice generated by CreloxP-mediated recombination. Curr. Biol. 6: 1307-1316, 1996.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1307-1316
-
-
Betz, U.A.1
Vosshenrich, C.A.2
Rajewsky, K.3
Muller, W.4
-
19
-
-
0029980672
-
Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform
-
BLENDY, J. A., K. H. KAESTNER, W. SCHMID, P. GASS, AND G. SCHUTZ. Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform. EMBO J. 15: 1098-1106, 1996.
-
(1996)
EMBO J.
, vol.15
, pp. 1098-1106
-
-
Blendy, J.A.1
Kaestner, K.H.2
Schmid, W.3
Gass, P.4
Schutz, G.5
-
20
-
-
0027476024
-
A synaptic model of memory: Long-term potentiation in the hippocampus
-
BLISS, T., AND G. COLLINGRIDGE. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361: 31-39, 1993.
-
(1993)
Nature
, vol.361
, pp. 31-39
-
-
Bliss, T.1
Collingridge, G.2
-
21
-
-
0021358883
-
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
-
BRADLEY, A., M. EVANS, M. H. KAUFMAN, AND E. ROBERTSON. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 309: 255-256, 1984.
-
(1984)
Nature
, vol.309
, pp. 255-256
-
-
Bradley, A.1
Evans, M.2
Kaufman, M.H.3
Robertson, E.4
-
22
-
-
0022567742
-
Embryo-derived stem cells: A tool for elucidating the developmental genetics of the mouse
-
BRADLEY, A., AND E. ROBERTSON. Embryo-derived stem cells: a tool for elucidating the developmental genetics of the mouse. Curr. Top. Dev. Biol. 20: 357-371, 1986.
-
(1986)
Curr. Top. Dev. Biol.
, vol.20
, pp. 357-371
-
-
Bradley, A.1
Robertson, E.2
-
23
-
-
0028874707
-
A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes
-
BRADSHAW, M. S., J. A. BOLLEKENS, AND F. H. RUDDLE. A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes. Nucleic Acids Res. 23: 4850-4856, 1995.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 4850-4856
-
-
Bradshaw, M.S.1
Bollekens, J.A.2
Ruddle, F.H.3
-
24
-
-
0031581209
-
A role for the Ras signalling pathway in synaptic transmission and long-term memory
-
BRAMBILLA, R., N. GNESUTTA, L. MINICHIELLO, G. WHITE, A. J. ROYLANCE, C. E. HERRON, M. RAMSEY, D. P. WOLFER, V. CESTARI, C. ROSSIARNAUD, S. G. N. GRANT, P. F. CHAPMAN, H. P. LIPP, E. STURANI, AND R. KLEIN. A role for the Ras signalling pathway in synaptic transmission and long-term memory. Nature 390: 281-286, 1997.
-
(1997)
Nature
, vol.390
, pp. 281-286
-
-
Brambilla, R.1
Gnesutta, N.2
Minichiello, L.3
White, G.4
Roylance, A.J.5
Herron, C.E.6
Ramsey, M.7
Wolfer, D.P.8
Cestari, V.9
Rossiarnaud, C.10
Grant, S.G.N.11
Chapman, P.F.12
Lipp, H.P.13
Sturani, E.14
Klein, R.15
-
25
-
-
0028256226
-
GFAP promoter directs astrocyte-specific expression in transgenic mice
-
BRENNER, M., W. KISSEBERTH, Y. SU, F. BESNARD, AND A. MESSING. GFAP promoter directs astrocyte-specific expression in transgenic mice. J. Neurosci. 14: 1030-1037, 1994.
-
(1994)
J. Neurosci.
, vol.14
, pp. 1030-1037
-
-
Brenner, M.1
Kisseberth, W.2
Su, Y.3
Besnard, F.4
Messing, A.5
-
26
-
-
0028114610
-
Anxiolytic-like effects of the novel cholinergic channel activator ABT-418
-
BRIONI, J. D., A. B. O'NEILL, D. B. KIM, M. J. BUCKLEY, M. W. DECKER, AND S. P. ARNERIC. Anxiolytic-like effects of the novel cholinergic channel activator ABT-418. J. Pharmacol. Exp. Ther. 271: 353-361, 1994.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.271
, pp. 353-361
-
-
Brioni, J.D.1
O'Neill, A.B.2
Kim, D.B.3
Buckley, M.J.4
Decker, M.W.5
Arneric, S.P.6
-
27
-
-
0029969678
-
Mechanisms of selective motor neuron death in ALS: Insights from transgenic mouse models of motor neuron disease
-
BRUIJN, L., AND D. CLEVELAND. Mechanisms of selective motor neuron death in ALS: insights from transgenic mouse models of motor neuron disease. Neuropathol. Appl. Neurobiol. 22: 373-387, 1996.
-
(1996)
Neuropathol. Appl. Neurobiol.
, vol.22
, pp. 373-387
-
-
Bruijn, L.1
Cleveland, D.2
-
28
-
-
0030273253
-
General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel
-
BRUNET, L., G. GOLD, AND J. NGAI. General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel. Neuron 17: 681-693, 1996.
-
(1996)
Neuron
, vol.17
, pp. 681-693
-
-
Brunet, L.1
Gold, G.2
Ngai, J.3
-
30
-
-
0025237565
-
Behavioral and biochemical changes monitored in two inbred strains of mice during exploration of an unfamiliar environment
-
CABIB, S., S. ALGERI, C. PEREGO, AND S. PUGLISI-ALLEGRA. Behavioral and biochemical changes monitored in two inbred strains of mice during exploration of an unfamiliar environment. Physiol. Behav. 47: 749-753, 1990.
-
(1990)
Physiol. Behav.
, vol.47
, pp. 749-753
-
-
Cabib, S.1
Algeri, S.2
Perego, C.3
Puglisi-Allegra, S.4
-
31
-
-
0030051050
-
Synaptic vesicle biogenesis, docking, and fusion: A molecular description
-
CALAKOS, N., AND R. H. SCHELLER. Synaptic vesicle biogenesis, docking, and fusion: a molecular description. Physiol. Rev. 76: 1-29, 1996.
-
(1996)
Physiol. Rev.
, vol.76
, pp. 1-29
-
-
Calakos, N.1
Scheller, R.H.2
-
32
-
-
0024328536
-
Altering the genome by homologous recombination
-
CAPECCHI, M. Altering the genome by homologous recombination. Science 244: 1288-1292, 1989.
-
(1989)
Science
, vol.244
, pp. 1288-1292
-
-
Capecchi, M.1
-
33
-
-
0024564718
-
The new mouse genetics: Altering the genome by gene targeting
-
CAPECCHI, M. R. The new mouse genetics: altering the genome by gene targeting. Trends Genet. 5: 70-76, 1989.
-
(1989)
Trends Genet.
, vol.5
, pp. 70-76
-
-
Capecchi, M.R.1
-
34
-
-
0029066498
-
Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA
-
CASES, O., I. SEIF, J. GRIMSBY, P. GASPAR, K. CHEN, S. POURNIN, U. MULLER, M. AGUET, C. BABINET, J. C. SHIH, AND E. DE MAEYER. Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA. Science 268: 1763-1766, 1995.
-
(1995)
Science
, vol.268
, pp. 1763-1766
-
-
Cases, O.1
Seif, I.2
Grimsby, J.3
Gaspar, P.4
Chen, K.5
Pournin, S.6
Muller, U.7
Aguet, M.8
Babinet, C.9
Shih, J.C.10
De Maeyer, E.11
-
35
-
-
16144362555
-
Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11
-
CASTILLA, L., C. WIJMENGA, Q. WANG, T. STACY, N. SPECK, M. ECKHAUS, M. MARIN-PADILLA, F. COLLINS, A. WYNSHAWBORIS, AND P. LIU. Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11. Cell 87: 687-696, 1996.
-
(1996)
Cell
, vol.87
, pp. 687-696
-
-
Castilla, L.1
Wijmenga, C.2
Wang, Q.3
Stacy, T.4
Speck, N.5
Eckhaus, M.6
Marin-Padilla, M.7
Collins, F.8
Wynshawboris, A.9
Liu, P.10
-
36
-
-
0029026638
-
Structure and function of voltage-gated ion channels
-
CATTERALL, W. Structure and function of voltage-gated ion channels. Annu. Rev. Biochem. 64: 493-531, 1995.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 493-531
-
-
Catterall, W.1
-
37
-
-
0030197964
-
Transgenesis in rats: Technical aspects and models
-
CHARREAU, B., L. TESSON, J. P. SOULILLOU, C. POURCEL, AND I. ANEGON. Transgenesis in rats: technical aspects and models. Transgenic Res. 5: 223-234, 1996.
-
(1996)
Transgenic Res.
, vol.5
, pp. 223-234
-
-
Charreau, B.1
Tesson, L.2
Soulillou, J.P.3
Pourcel, C.4
Anegon, I.5
-
38
-
-
0029620817
-
Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice
-
CHEN, C., M. KANO, A. ABELIOVICH, L. CHEN, S. BAO, J. J. KIM, K. HASHIMOTO, R. F. THOMPSON, AND S. TONEGAWA. Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice. Cell 83: 1233-1242, 1995.
-
(1995)
Cell
, vol.83
, pp. 1233-1242
-
-
Chen, C.1
Kano, M.2
Abeliovich, A.3
Chen, L.4
Bao, S.5
Kim, J.J.6
Hashimoto, K.7
Thompson, R.F.8
Tonegawa, S.9
-
39
-
-
0029957561
-
Hippocampal lesions impair contextual fear conditioning in two strains of mice
-
CHEN, C., J. J. KIM, R. F. THOMPSON, AND S. TONEGAWA. Hippocampal lesions impair contextual fear conditioning in two strains of mice. Behav. Neurosci. 110: 1177-1180, 1996.
-
(1996)
Behav. Neurosci.
, vol.110
, pp. 1177-1180
-
-
Chen, C.1
Kim, J.J.2
Thompson, R.F.3
Tonegawa, S.4
-
40
-
-
0031055834
-
Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain
-
CHEN, C., AND S. TONEGAWA. Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain. Annu. Rev. Neurosci. 20: 157-184, 1997.
-
(1997)
Annu. Rev. Neurosci.
, vol.20
, pp. 157-184
-
-
Chen, C.1
Tonegawa, S.2
-
41
-
-
0029096114
-
Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
CHIU, A., P. ZHAJ, M. DAL CANTO, T. PETERS, Y. KWON, S. PRATTIS, AND M. GURNEY. Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis. Mol. Cell Neurosci. 6: 349-362, 1995.
-
(1995)
Mol. Cell Neurosci.
, vol.6
, pp. 349-362
-
-
Chiu, A.1
Zhaj, P.2
Dal Canto, M.3
Peters, T.4
Kwon, Y.5
Prattis, S.6
Gurney, M.7
-
42
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
-
CITRON, M., D. WESTAWAY, W. XIA, G. CARLSON, T. DIEHL, G. LEVESQUE, K. JOHNSON-WOOD, M. LEE, P. SEUBERT, A. DAVIS, D. KHOLODENKO, R. MOTTER, R. SHERRINGTON, B. PERRY, H. YAO, R. STROME, I. LIEBERBURG, J. ROMMENS, S. KIM, D. SCHENK, P. FRASER, P. ST. GEORGE HYSLOP, AND D. SELKOE. Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice. Nature Med. 3: 67-72, 1997.
-
(1997)
Nature Med.
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St. George Hyslop, P.22
Selkoe, D.23
more..
-
43
-
-
0029121640
-
Inactivation in vivo of metabotropic glutamate receptor 1 by specific chromosomal insertion of reporter gene lacZ
-
CONQUET, F. Inactivation in vivo of metabotropic glutamate receptor 1 by specific chromosomal insertion of reporter gene lacZ. Neuropharmacology 34: 865-870, 1995.
-
(1995)
Neuropharmacology
, vol.34
, pp. 865-870
-
-
Conquet, F.1
-
44
-
-
0027997686
-
Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1
-
CONQUET, F., Z. I. BASHIR, C. H. DAVIES, H. DANIEL, F. FERRAGUTI, F. BORDI, K. FRANZ-BACON, A. REGGIANI, V. MATARESE, F. CONDE, G. L. COLLINGRIDGE, AND F. CREPEL. Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1. Nature 372: 237-243, 1994.
-
(1994)
Nature
, vol.372
, pp. 237-243
-
-
Conquet, F.1
Bashir, Z.I.2
Davies, C.H.3
Daniel, H.4
Ferraguti, F.5
Bordi, F.6
Franz-Bacon, K.7
Reggiani, A.8
Matarese, V.9
Conde, F.10
Collingridge, G.L.11
Crepel, F.12
-
45
-
-
0028916152
-
Death before birth: Clues from gene knockouts and mutations
-
COPP, A. Death before birth: clues from gene knockouts and mutations. Trends Genet. 11: 87-93, 1995.
-
(1995)
Trends Genet.
, vol.11
, pp. 87-93
-
-
Copp, A.1
-
47
-
-
0027465098
-
Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis
-
COTE, F., J.-F. COLLARD, AND J.-P. JULIEN. Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. Cell 73: 35-46, 1993.
-
(1993)
Cell
, vol.73
, pp. 35-46
-
-
Cote, F.1
Collard, J.-F.2
Julien, J.-P.3
-
48
-
-
0021972205
-
Exploratory behavior models of anxiety in mice
-
CRAWLEY, J. N. Exploratory behavior models of anxiety in mice. Neurosci. Biobehav. Rev. 9: 37-44, 1985.
-
(1985)
Neurosci. Biobehav. Rev.
, vol.9
, pp. 37-44
-
-
Crawley, J.N.1
-
49
-
-
0009703087
-
Behavioral phenotypes of inbred mouse strains: Implications and recommendations for molecular studies
-
CRAWLEY, J. N., J. K. BELKNAP, A. COLLINS, J. C. CRABBE, W. FRANKEL, N. HENDERSON, R. J. HITZEMANN, S. C. MAXSON, L. L. MINER, A. J. SILVA, J. M. WEHNER, A. WYNSHAW-BORIS, AND R. PAYLOR. Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology 132: 107-124, 1997.
-
(1997)
Psychopharmacology
, vol.132
, pp. 107-124
-
-
Crawley, J.N.1
Belknap, J.K.2
Collins, A.3
Crabbe, J.C.4
Frankel, W.5
Henderson, N.6
Hitzemann, R.J.7
Maxson, S.C.8
Miner, L.L.9
Silva, A.J.10
Wehner, J.M.11
Wynshaw-Boris, A.12
Paylor, R.13
-
50
-
-
0031171578
-
A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice
-
CRAWLEY, J. N., AND R. PAYLOR. A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice. Horm. Behav. 31: 197-211, 1997.
-
(1997)
Horm. Behav.
, vol.31
, pp. 197-211
-
-
Crawley, J.N.1
Paylor, R.2
-
51
-
-
1842289165
-
Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrate in the rod and head domains of neurofilament-L
-
CROW, J., Y. YE, M. STRONG, M. KIRK, S. BARNES, AND J. BECKMAN. Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrate in the rod and head domains of neurofilament-L. J. Neurochem. 69: 1945-1953, 1997.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1945-1953
-
-
Crow, J.1
Ye, Y.2
Strong, M.3
Kirk, M.4
Barnes, S.5
Beckman, J.6
-
52
-
-
0029328327
-
Steps towards a mouse model of Alzheimer's disease
-
CROWTHER, R. Steps towards a mouse model of Alzheimer's disease. Bioessays 17: 593-595, 1995.
-
(1995)
Bioessays
, vol.17
, pp. 593-595
-
-
Crowther, R.1
-
54
-
-
0030916609
-
A low expressor line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase (SOD1) gene develops pathological changes that more closely resemble those in human amyotrophic lateral sclerosis
-
DAL CANTO, M., AND M. GURNEY. A low expressor line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase (SOD1) gene develops pathological changes that more closely resemble those in human amyotrophic lateral sclerosis. Acta Neuropathol. 93: 537-550, 1997.
-
(1997)
Acta Neuropathol.
, vol.93
, pp. 537-550
-
-
Dal Canto, M.1
Gurney, M.2
-
55
-
-
0028260128
-
Reverse genetics of the mouse central nervous system: Targeted genetic analysis of neuropeptide function and reverse genetic screens for genes involved in human neurodegenerative disease
-
DAVIES, R. W., E. J. GALLAGHER, AND A. SAVIOZ. Reverse genetics of the mouse central nervous system: targeted genetic analysis of neuropeptide function and reverse genetic screens for genes involved in human neurodegenerative disease. Prog. Neurobiol. 42: 319-331, 1994.
-
(1994)
Prog. Neurobiol.
, vol.42
, pp. 319-331
-
-
Davies, R.W.1
Gallagher, E.J.2
Savioz, A.3
-
56
-
-
0028788476
-
Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth
-
DECHIARA, T. M., R. VEJSADA, W. T. POUEYMIROU, A. ACHESON, C. SURI, J. C. CONOVER, B. FRIEDMAN, J. McCLAIN, L. PAN, AND N. STAHL. Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth. Cell 83: 313-322, 1995.
-
(1995)
Cell
, vol.83
, pp. 313-322
-
-
Dechiara, T.M.1
Vejsada, R.2
Poueymirou, W.T.3
Acheson, A.4
Suri, C.5
Conover, J.C.6
Friedman, B.7
McClain, J.8
Pan, L.9
Stahl, N.10
-
57
-
-
0028082058
-
Progress in mapping human epilepsy genes
-
DELGADO-ESCUETA, A. V., J. M. SERRATOSA, A. LIU, K. WEISSBECKER, M. T. MEDINA, M. GEE, L. J. TREIMAN, AND R. S. SPARKES. Progress in mapping human epilepsy genes. Epilepsia 35, Suppl: S29-S40, 1994.
-
(1994)
Epilepsia
, vol.35
, Issue.SUPPL.
-
-
Delgado-Escueta, A.V.1
Serratosa, J.M.2
Liu, A.3
Weissbecker, K.4
Medina, M.T.5
Gee, M.6
Treiman, L.J.7
Sparkes, R.S.8
-
58
-
-
0021368680
-
Neurofibrillary axonal swellings and amyotrophic lateral sclerosis
-
DELISLE, M., AND S. CARPENTER. Neurofibrillary axonal swellings and amyotrophic lateral sclerosis. J. Neurol. Sci. 63: 241-250, 1984.
-
(1984)
J. Neurol. Sci.
, vol.63
, pp. 241-250
-
-
Delisle, M.1
Carpenter, S.2
-
59
-
-
0029919753
-
TAXI/UAS: A molecular switch to control expression of genes in vivo
-
DELORT, J. P., AND M. R. CAPECCHI. TAXI/UAS: a molecular switch to control expression of genes in vivo. Hum. Gene Ther. 7: 809-820, 1996.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 809-820
-
-
Delort, J.P.1
Capecchi, M.R.2
-
60
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase
-
DENG, H.-X., A. HENTATI, J. TAINER, Z. IQBAL, A. CAYABYAB, W.-Y. HUNG, E. GETZOFF, P. HU, B. HERZFELDT, P. ROOS, C. WARNER, AND T. SIDDIQUE. Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase. Science 261: 1047-1051, 1993.
-
(1993)
Science
, vol.261
, pp. 1047-1051
-
-
Deng, H.-X.1
Hentati, A.2
Tainer, J.3
Iqbal, Z.4
Cayabyab, A.5
Hung, W.-Y.6
Getzoff, E.7
Hu, P.8
Herzfeldt, B.9
Roos, P.10
Warner, C.11
Siddique, T.12
-
61
-
-
0029335574
-
An insertional mutation in the BTF3 transcription factor gene leads to an early postimplantation lethality in mice
-
DENG, J. M., AND R. R. BEHRINGER. An insertional mutation in the BTF3 transcription factor gene leads to an early postimplantation lethality in mice. Transgenic Res. 4: 264-269, 1995.
-
(1995)
Transgenic Res.
, vol.4
, pp. 264-269
-
-
Deng, J.M.1
Behringer, R.R.2
-
62
-
-
0030792310
-
Differences in the liability to self-administer intravenous cocaine between C57BL/6 x SJL and BALB/cByJ mice
-
DEROCHE, V., S. B. CAINE, C. J. HEYSER, I. POLIS, G. F. KOOB, AND L. H. GOLD. Differences in the liability to self-administer intravenous cocaine between C57BL/6 x SJL and BALB/cByJ mice. Pharmacol. Biochem. Behav. 57: 429-440, 1997.
-
(1997)
Pharmacol. Biochem. Behav.
, vol.57
, pp. 429-440
-
-
Deroche, V.1
Caine, S.B.2
Heyser, C.J.3
Polis, I.4
Koob, G.F.5
Gold, L.H.6
-
63
-
-
0032556859
-
Deficiency in presenilin-1 inhibits the normal cleavage of amyloid precursor protein
-
DE STROOPER, B., P. SAFTIG, K. CRAESSAERTS, H. VANDERSTICHELE, G. GUHDE, W. ANNAERT, K. VON FIGURA, AND F. VAN LEUVEN. Deficiency in presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature 391: 387-390, 1998.
-
(1998)
Nature
, vol.391
, pp. 387-390
-
-
De Strooper, B.1
Saftig, P.2
Craessaerts, K.3
Vanderstichele, H.4
Guhde, G.5
Annaert, W.6
Von Figura, K.7
Van Leuven, F.8
-
64
-
-
0030293854
-
Protein topology of presenilin 1
-
DOAN, A., G. THINAKARAN, D. BORCHELT, H. SLUNT, T. RATOVITSKI, M. PODLISNY, D. SELKOE, M. SEEGER, S. GANDY, D. PRICE, AND S. SISODIA. Protein topology of presenilin 1. Neuron 17: 1023-1030, 1996.
-
(1996)
Neuron
, vol.17
, pp. 1023-1030
-
-
Doan, A.1
Thinakaran, G.2
Borchelt, D.3
Slunt, H.4
Ratovitski, T.5
Podlisny, M.6
Selkoe, D.7
Seeger, M.8
Gandy, S.9
Price, D.10
Sisodia, S.11
-
65
-
-
0026730466
-
Cystic fibrosis in the mouse by targeted insertional mutagenesis
-
DORIN, J. R., P. DICKINSON, E. W. ALTON, S. N. SMITH, D. M. GEDDES, B. J. STEVENSON, W. L. KIMBER, S. FLEMING, A. R. CLARKE, M. L. HOOPER, L. ANDERSON, R. S. P. BEDDINGTON, AND D. J. PORTEOUS. Cystic fibrosis in the mouse by targeted insertional mutagenesis. Nature 359: 211-215, 1992.
-
(1992)
Nature
, vol.359
, pp. 211-215
-
-
Dorin, J.R.1
Dickinson, P.2
Alton, E.W.3
Smith, S.N.4
Geddes, D.M.5
Stevenson, B.J.6
Kimber, W.L.7
Fleming, S.8
Clarke, A.R.9
Hooper, M.L.10
Anderson, L.11
Beddington, R.S.P.12
Porteous, D.J.13
-
66
-
-
0028003254
-
Long-term survival of the exon 10 insertional cystic fibrosis mutant mouse is a consequence of low level residual wild-type CFTR gene expression
-
DORIN, J. R., B. J. STEVENSON, S. FLEMING, E. W. ALTON, P. DICKINSON, AND D. J. PORTEOUS. Long-term survival of the exon 10 insertional cystic fibrosis mutant mouse is a consequence of low level residual wild-type CFTR gene expression. Mamm. Genome 5: 465-472, 1994.
-
(1994)
Mamm. Genome
, vol.5
, pp. 465-472
-
-
Dorin, J.R.1
Stevenson, B.J.2
Fleming, S.3
Alton, E.W.4
Dickinson, P.5
Porteous, D.J.6
-
68
-
-
0030245592
-
Dopamine and opioid regulation of the memory retrieval recovery in mice
-
DUBROVINA, N. I., AND R. ILYUTCHENOK. Dopamine and opioid regulation of the memory retrieval recovery in mice. Behav. Brain Res. 79: 23-29, 1996.
-
(1996)
Behav. Brain Res.
, vol.79
, pp. 23-29
-
-
Dubrovina, N.I.1
Ilyutchenok, R.2
-
70
-
-
0029761783
-
Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene
-
EBRADLIDZE, A., D. ROSSI, S. TONEGAWA, AND N. SLATER. Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene. J. Neurosci. 16: 5014-5025, 1996.
-
(1996)
J. Neurosci.
, vol.16
, pp. 5014-5025
-
-
Ebradlidze, A.1
Rossi, D.2
Tonegawa, S.3
Slater, N.4
-
72
-
-
0029767838
-
Ligand-activated site-specific recombination in mice
-
FEIL, R., J. BROCARD, B. MASCREZ, M. LEMEUR, D. METZGER, AND P. CHAMBON. Ligand-activated site-specific recombination in mice. Proc. Natl. Acad. Sci. USA 93: 10887-10890, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10887-10890
-
-
Feil, R.1
Brocard, J.2
Mascrez, B.3
Lemeur, M.4
Metzger, D.5
Chambon, P.6
-
73
-
-
0031589555
-
Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains
-
FEIL, R., J. WAGNER, D. METZGER, AND P. CHAMBON. Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem. Biophys. Res. Commun. 237: 752-757, 1997.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.237
, pp. 752-757
-
-
Feil, R.1
Wagner, J.2
Metzger, D.3
Chambon, P.4
-
74
-
-
0028001606
-
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
-
FIGLEWICZ, D., A. KRIZUS, M. MARTINOLI, V. MEININGER, M. DIB, G. ROULEAU, AND J.-P. JULIEN. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum. Mol. Genet. 3: 1757-1761, 1994.
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 1757-1761
-
-
Figlewicz, D.1
Krizus, A.2
Martinoli, M.3
Meininger, V.4
Dib, M.5
Rouleau, G.6
Julien, J.-P.7
-
75
-
-
0028030468
-
Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death
-
FORREST, D., M. YUZAKI, H. D. SOARES, L. NG, D. C. LUK, M. SHENG, C. L. STEWART, J. I. MORGAN, J. A. CONNOR, AND T. CURRAN. Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Neuron 13: 325-338, 1994.
-
(1994)
Neuron
, vol.13
, pp. 325-338
-
-
Forrest, D.1
Yuzaki, M.2
Soares, H.D.3
Ng, L.4
Luk, D.C.5
Sheng, M.6
Stewart, C.L.7
Morgan, J.I.8
Connor, J.A.9
Curran, T.10
-
76
-
-
0025063668
-
Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control
-
FORSS-PETTER, S., P. E. DANIELSON, S. CATSICAS, E. BATTENBERG, J. PRICE, M. NERENBERG, AND G. SUTCLIFFE. Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control. Neuron 5: 187-197, 1990.
-
(1990)
Neuron
, vol.5
, pp. 187-197
-
-
Forss-Petter, S.1
Danielson, P.E.2
Catsicas, S.3
Battenberg, E.4
Price, J.5
Nerenberg, M.6
Sutcliffe, G.7
-
77
-
-
0029053451
-
Superoxide radical and superoxide dismutases
-
FRIDOVICH, I. Superoxide radical and superoxide dismutases. Annu. Rev. Biochem. 64: 97-112, 1995.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 97-112
-
-
Fridovich, I.1
-
78
-
-
0025992469
-
Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice
-
FRIEDRICH, G., AND P. SORIANO. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev. 5: 1513-1523, 1991.
-
(1991)
Genes Dev.
, vol.5
, pp. 1513-1523
-
-
Friedrich, G.1
Soriano, P.2
-
79
-
-
0028071115
-
Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter
-
FURTH, P., L. ST. ONGE, H. BOGER, P. GRUSS, M. GOSSEN, A. KISTNER, H. BUJARD, AND L. HENNINGHAUSEN. Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc. Natl. Acad. Sci. USA 91: 9302-9306, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9302-9306
-
-
Furth, P.1
St. Onge, L.2
Boger, H.3
Gruss, P.4
Gossen, M.5
Kistner, A.6
Bujard, H.7
Henninghausen, L.8
-
80
-
-
0030964023
-
Interleukin-6 (IL-6): A molecule with both beneficial and destructive potentials
-
GADIENT, R., AND U. OTTEN. Interleukin-6 (IL-6): a molecule with both beneficial and destructive potentials. Prog. Neurobiol. 52:379-390, 1997.
-
(1997)
Prog. Neurobiol.
, vol.52
, pp. 379-390
-
-
Gadient, R.1
Otten, U.2
-
81
-
-
0042118412
-
Organotypic slice cultures: A technique has come of age
-
GAHWILER, B., M. CAPOGNA, D. DEBANNE, R. McKINNEY, AND S. THOMPSON. Organotypic slice cultures: a technique has come of age. Trends Neurosci. 20: 471-477, 1997.
-
(1997)
Trends Neurosci.
, vol.20
, pp. 471-477
-
-
Gahwiler, B.1
Capogna, M.2
Debanne, D.3
McKinney, R.4
Thompson, S.5
-
82
-
-
0030614913
-
Induction of Gαq-specific antisense RNA in vivo causes increased body mass and hyperadiposity
-
GALVIN-PARTON, P., X. CHEN, C. MOXHAM, AND C. MALBON. Induction of Gαq-specific antisense RNA in vivo causes increased body mass and hyperadiposity. J. Biol. Chem. 272: 4335-4341, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4335-4341
-
-
Galvin-Parton, P.1
Chen, X.2
Moxham, C.3
Malbon, C.4
-
83
-
-
0025884565
-
Functional architecture of the nicotinic acetylcholine receptor: From electric organ to brain
-
GALZI, J.-L., F. REVAH, A. BESSIS, AND J.-P. CHANGEUX. Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain. Annu. Rev. Pharmacol. 31: 37-72, 1991.
-
(1991)
Annu. Rev. Pharmacol.
, vol.31
, pp. 37-72
-
-
Galzi, J.-L.1
Revah, F.2
Bessis, A.3
Changeux, J.-P.4
-
84
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
-
GAMES, D., D. ADAMS, R. ALESSANDRINI, R. BARBOUR, P. BERTHELETTE, C. BLACKWELL, T. CARR, J. CLEMENS, T. DONALDSON, F. GILLESPIE, T. GUIDO, S. HAGOPIAN, S. JOHNSONWOOD, K. KHAN, M. LEE, P. LIEBOWITZ, I. LIEBERBURG, S. LITTLE, E. MASLIAH, L. McCONLOGUE, M. MONTOYA-ZAVALA, L. MUCKE, L. PAGANINI, AND E. PENNIMAN. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 373: 523-527, 1995.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
Guido, T.11
Hagopian, S.12
Johnsonwood, S.13
Khan, K.14
Lee, M.15
Liebowitz, P.16
Lieberburg, I.17
Little, S.18
Masliah, E.19
McConlogue, L.20
Montoya-Zavala, M.21
Mucke, L.22
Paganini, L.23
Penniman, E.24
more..
-
85
-
-
0028061861
-
2+ sensor for transmitter release at a central synapse
-
2+ sensor for transmitter release at a central synapse. Cell 79: 717-727, 1994.
-
(1994)
Cell
, vol.79
, pp. 717-727
-
-
Geppert, M.1
Goda, Y.2
Hammer, R.E.3
Li, C.4
Rosahl, T.W.5
Stevens, C.F.6
Sudhof, T.C.7
-
86
-
-
0029940557
-
Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype?
-
GERLAI, R. Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci. 19: 177-181, 1996.
-
(1996)
Trends Neurosci.
, vol.19
, pp. 177-181
-
-
Gerlai, R.1
-
87
-
-
9044254932
-
Impaired motor learning performance in cerebellar En-2 mutant mice
-
GERLAI, R., K. J. MILLEN, K. HERRUP, K. FABIEN, A. L. JOYNER, AND J. RODER. Impaired motor learning performance in cerebellar En-2 mutant mice. Behav. Neurosci. 110: 126-133, 1996.
-
(1996)
Behav. Neurosci.
, vol.110
, pp. 126-133
-
-
Gerlai, R.1
Millen, K.J.2
Herrup, K.3
Fabien, K.4
Joyner, A.L.5
Roder, J.6
-
88
-
-
0030071106
-
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
-
GIROS, B., M. JABER, S. R. JONES, R. M. WIGHTMAN, AND M. G. CARON. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379: 606-612, 1996.
-
(1996)
Nature
, vol.379
, pp. 606-612
-
-
Giros, B.1
Jaber, M.2
Jones, S.R.3
Wightman, R.M.4
Caron, M.G.5
-
89
-
-
0031033952
-
Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis
-
GLABINSKI, A. R., M. TANI, R. M. STRIETER, V. K. TUOHY, AND R. M. RANSOHOFF. Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis. Am. J. Pathol. 150: 617-630, 1997.
-
(1997)
Am. J. Pathol.
, vol.150
, pp. 617-630
-
-
Glabinski, A.R.1
Tani, M.2
Strieter, R.M.3
Tuohy, V.K.4
Ransohoff, R.M.5
-
90
-
-
0023132387
-
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease
-
GOLDGABER, D., M. LERMAN, O. McBRIDE, U. SAFFIOT, AND D. GADJUSEK. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science 235: 877-880, 1987.
-
(1987)
Science
, vol.235
, pp. 877-880
-
-
Goldgaber, D.1
Lerman, M.2
McBride, O.3
Saffiot, U.4
Gadjusek, D.5
-
91
-
-
0030031636
-
A transgenic mouse model of the slow-channel syndrome
-
GOMEZ, C., B. BHATTACHARYYA, P. CHARNET, J. DAY, C. LABARCA, R. WOLLMANN, AND E. LAMBERT. A transgenic mouse model of the slow-channel syndrome. Muscle Nerve 19: 79-87, 1996.
-
(1996)
Muscle Nerve
, vol.19
, pp. 79-87
-
-
Gomez, C.1
Bhattacharyya, B.2
Charnet, P.3
Day, J.4
Labarca, C.5
Wollmann, R.6
Lambert, E.7
-
92
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
GOSSEN, M., AND H. BUJARD. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89: 5547-5551, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
93
-
-
0029022369
-
Transcriptional activation by tetracyclines in mammalian cells
-
GOSSEN, M., S. FREUNDLIEB, G. BENDER, G. MULLER, W. HILLEN, AND H. BUJARD. Transcriptional activation by tetracyclines in mammalian cells. Science 268: 1766-1769, 1995.
-
(1995)
Science
, vol.268
, pp. 1766-1769
-
-
Gossen, M.1
Freundlieb, S.2
Bender, G.3
Muller, G.4
Hillen, W.5
Bujard, H.6
-
94
-
-
0027286686
-
The proximal region of the MBP gene promoter is sufficient to induce oligodendroglial-specific expression in transgenic mice
-
GOUJET-ZALC, C., C. BABINET, M. MONGE, S. TIMSIT, F. CABON, A. GANSMULLER, M. MIURA, M. SANCHEZ, S. POURNIN, AND K. MIKOSHIBA. The proximal region of the MBP gene promoter is sufficient to induce oligodendroglial-specific expression in transgenic mice. Eur. J. Neurosci. 5: 624-632, 1993.
-
(1993)
Eur. J. Neurosci.
, vol.5
, pp. 624-632
-
-
Goujet-Zalc, C.1
Babinet, C.2
Monge, M.3
Timsit, S.4
Cabon, F.5
Gansmuller, A.6
Miura, M.7
Sanchez, M.8
Pournin, S.9
Mikoshiba, K.10
-
95
-
-
0028812674
-
Genetic differences in intravenous cocaine self-administration between C57BL/6J and DBA/2J mice
-
GRAHAME, N. J., AND C. L. CUNNINGHAM. Genetic differences in intravenous cocaine self-administration between C57BL/6J and DBA/2J mice. Psychopharmacology 122: 281-291, 1995.
-
(1995)
Psychopharmacology
, vol.122
, pp. 281-291
-
-
Grahame, N.J.1
Cunningham, C.L.2
-
96
-
-
0027402975
-
Synaptic vesicle phosphoproteins and regulation of synaptic function
-
GREENGARD, P., F. VALTORTA, A. J. CZERNIK, AND F. BENFENATI. Synaptic vesicle phosphoproteins and regulation of synaptic function. Science 259: 780-785, 1993.
-
(1993)
Science
, vol.259
, pp. 780-785
-
-
Greengard, P.1
Valtorta, F.2
Czernik, A.J.3
Benfenati, F.4
-
97
-
-
0028059099
-
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
-
GU, H., J. D. MARTH, P. C. ORBAN, H. MOSSMANN, AND K. RAJEWSKY. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 265: 103-106, 1994.
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
98
-
-
0029097465
-
Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors
-
GUNTHER, U., J. BENSON, D. BENKE, J. M. FRITSCHY, G. REYES, F. KNOFLACH, F. CRESTANI, A. AGUZZI, M. ARIGONI, Y. LANG, H. BLUETHMANN, H. MOHLER, AND B. LUSCHER. Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors. Proc. Natl. Acad. Sci. USA 92: 7749-7753, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7749-7753
-
-
Gunther, U.1
Benson, J.2
Benke, D.3
Fritschy, J.M.4
Reyes, G.5
Knoflach, F.6
Crestani, F.7
Aguzzi, A.8
Arigoni, M.9
Lang, Y.10
Bluethmann, H.11
Mohler, H.12
Luscher, B.13
-
99
-
-
0030927253
-
Transgenic animal models of familial amyotrophic lateral sclerosis
-
GURNEY, M. Transgenic animal models of familial amyotrophic lateral sclerosis. J. Neurol. 244, Suppl. S15-S20, 1997.
-
(1997)
J. Neurol.
, vol.244
, Issue.SUPPL.
-
-
Gurney, M.1
-
100
-
-
0030050727
-
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
-
GURNEY, M., F. CUTTING, P. ZHAI, A. DOBLE, C. TAYLOR, P. ANDRUS, AND E. HALL. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann. Neurol. 39: 147-157, 1996.
-
(1996)
Ann. Neurol.
, vol.39
, pp. 147-157
-
-
Gurney, M.1
Cutting, F.2
Zhai, P.3
Doble, A.4
Taylor, C.5
Andrus, P.6
Hall, E.7
-
101
-
-
0028284779
-
Motor neuron degeneration in mice expressing a human Cu,Zn superoxide dismutase mutation
-
GURNEY, M., H. PU, A. CHIU, M. DAL CANTO, C. POLCHOW, D. ALEXANDER, J. CALIDENDO, A. HENTATI, Y. KWON, H. DENG, W. CHEN, P. ZHAI, R. SUFIT, AND T. SIDDIQUE. Motor neuron degeneration in mice expressing a human Cu,Zn superoxide dismutase mutation. Science 264: 1772-1775, 1994.
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.1
Pu, H.2
Chiu, A.3
Dal Canto, M.4
Polchow, C.5
Alexander, D.6
Calidendo, J.7
Hentati, A.8
Kwon, Y.9
Deng, H.10
Chen, W.11
Zhai, P.12
Sufit, R.13
Siddique, T.14
-
102
-
-
0030922421
-
Presenilins: Genes for life and death
-
HAASS, C. Presenilins: genes for life and death. Neuron 18: 687-690, 1997.
-
(1997)
Neuron
, vol.18
, pp. 687-690
-
-
Haass, C.1
-
103
-
-
0027985408
-
Efficiency of insertion versus replacement vector targeting varies at different chromosomal loci
-
HASTY, P., M. CRIST, M. GROMPE, AND A. BRADLEY. Efficiency of insertion versus replacement vector targeting varies at different chromosomal loci. Mol. Cell. Biol. 14: 8385-8390, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 8385-8390
-
-
Hasty, P.1
Crist, M.2
Grompe, M.3
Bradley, A.4
-
105
-
-
0029586870
-
Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system
-
HENNIGHAUSEN, L., R. J. WALL, U. TILLMANN, M. LI, AND P. A. FURTH. Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system. J. Cell. Biochem. 59: 463-472, 1995.
-
(1995)
J. Cell. Biochem.
, vol.59
, pp. 463-472
-
-
Hennighausen, L.1
Wall, R.J.2
Tillmann, U.3
Li, M.4
Furth, P.A.5
-
107
-
-
0026042995
-
Cytopathology of amyotrophic lateral sclerosis
-
edited by L. Rowland. New York: Raven
-
HIRANO, A. Cytopathology of amyotrophic lateral sclerosis. In: Advances in Neurology and Other Motor Neuron Diseases, edited by L. Rowland. New York: Raven, 1991, p. 91-101.
-
(1991)
Advances in Neurology and Other Motor Neuron Diseases
, pp. 91-101
-
-
Hirano, A.1
-
108
-
-
0005673882
-
Interaction of the bacteriophage P1 recombinase Cre with the recombining site loxP
-
HOESS, R., AND K. ABREMSKI. Interaction of the bacteriophage P1 recombinase Cre with the recombining site loxP. Proc. Natl. Acad. Sci. USA 81: 1026-1029, 1984.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 1026-1029
-
-
Hoess, R.1
Abremski, K.2
-
109
-
-
0023046599
-
The role of the loxP spacer region in P1 site-specific recombination
-
HOESS, R., A. WIERZBICKI, AND K. ABREMSKI. The role of the loxP spacer region in P1 site-specific recombination. Nucleic Acids Res. 14: 2287-2300, 1986.
-
(1986)
Nucleic Acids Res.
, vol.14
, pp. 2287-2300
-
-
Hoess, R.1
Wierzbicki, A.2
Abremski, K.3
-
110
-
-
1842394365
-
P1 site-specific recombination: Nucleotide sequence of the recombining sites
-
HOESS, R., M. ZIESE, AND N. STERNBERG. P1 site-specific recombination: nucleotide sequence of the recombining sites. Proc. Natl. Acad. Sci. USA 79: 3398-3402, 1982.
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 3398-3402
-
-
Hoess, R.1
Ziese, M.2
Sternberg, N.3
-
112
-
-
0030615289
-
Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: Lack of effect on responses to ethanol, pentobarbital, and general anesthetics
-
HOMANICS, G. E., C. FERGUSON, J. J. QUINLAN, J. DAGGETT, K. SNYDER, C. LAGENAUR, Z. P. MI, X. H. WANG, D. R. GRAYSON, AND L. L. FIRESTONE. Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: lack of effect on responses to ethanol, pentobarbital, and general anesthetics. Mol Pharmacol 51: 588-96, 1997.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 588-596
-
-
Homanics, G.E.1
Ferguson, C.2
Quinlan, J.J.3
Daggett, J.4
Snyder, K.5
Lagenaur, C.6
Mi, Z.P.7
Wang, X.H.8
Grayson, D.R.9
Firestone, L.L.10
-
113
-
-
0028829134
-
Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: The use of mutant mice and pharmacological antagonists
-
HSIA, A. Y., P.A. SALIN, P. E. CASTILLO, A. AIBA, A. ABELIOVICH, S. TONEGAWA, AND R. A. NICOLL. Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: the use of mutant mice and pharmacological antagonists. Neuropharmacology 34: 1567-72, 1995.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1567-1572
-
-
Hsia, A.Y.1
Salin, P.A.2
Castillo, P.E.3
Aiba, A.4
Abeliovich, A.5
Tonegawa, S.6
Nicoll, R.A.7
-
114
-
-
0028810244
-
Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins
-
HSIAO, K., D. BORCHELT, K. OLSON, R. JOHANNSDOTTIR, C. KITT, W. YUNIS, S. XU, C. ECKMAN, S. YOUNKIN, D. PRICE, C. IADECOLA, H. CLARK, AND G. CARLSON. Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins. Neuron 15: 1203-1218, 1995.
-
(1995)
Neuron
, vol.15
, pp. 1203-1218
-
-
Hsiao, K.1
Borchelt, D.2
Olson, K.3
Johannsdottir, R.4
Kitt, C.5
Yunis, W.6
Xu, S.7
Eckman, C.8
Younkin, S.9
Price, D.10
Iadecola, C.11
Clark, H.12
Carlson, G.13
-
115
-
-
0029742199
-
Correlative memory deficits, Aβ elevation and amyloid plaques in transgenic mice
-
HSIAO, K., P. CHAPMAN, S. NILSEN, C. ECKMAN, Y. HARIGAYA, S. YOUNKIN, F. YANG, AND G. COLE. Correlative memory deficits, Aβ elevation and amyloid plaques in transgenic mice. Science 274: 99-102 1996.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
116
-
-
9444240943
-
Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways
-
HUANG, Y. Y., M. E. BACH, H. P. LIPP, M. ZHUO, D. P. WOLFER, R. D. HAWKINS, L. SCHOONJANS, E. R. KANDEL, J. M. GODFRAIND, R. MULLIGAN, D. COLLEN, AND P. CARMELIET. Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways. Proc. Natl. Acad. Sci. USA 93: 8699-8704, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8699-8704
-
-
Huang, Y.Y.1
Bach, M.E.2
Lipp, H.P.3
Zhuo, M.4
Wolfer, D.P.5
Hawkins, R.D.6
Schoonjans, L.7
Kandel, E.R.8
Godfraind, J.M.9
Mulligan, R.10
Collen, D.11
Carmeliet, P.12
-
117
-
-
0029730658
-
ALS therapy: Targets for the future
-
HUGON, J. ALS therapy: targets for the future. Neurology 47, Suppl: S251-S254, 1996.
-
(1996)
Neurology
, vol.47
, Issue.SUPPL.
-
-
Hugon, J.1
-
118
-
-
0028238472
-
Targeted mutation of the CREB gene: Compensation within the CREB/ATF family of transcription factors
-
HUMMLER, E., T. J. COLE, J. A. BLENDY, R. GANSS, A. AGUZZI, W. SCHMID, F. BEERMANN, AND G. SCHUTZ. Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors. Proc. Natl. Acad. Sci. USA 91: 5647-5651, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5647-5651
-
-
Hummler, E.1
Cole, T.J.2
Blendy, J.A.3
Ganss, R.4
Aguzzi, A.5
Schmid, W.6
Beermann, F.7
Schutz, G.8
-
119
-
-
0029143338
-
Reduced spontaneous activity of mice defective in the epsilon 4 subunit of the NMDA receptor channel
-
IKEDA, K., K. ARAKI, C. TAKAYAMA, Y. INOUE, T. YAGI, S. AIZAWA, AND M. MISHINA. Reduced spontaneous activity of mice defective in the epsilon 4 subunit of the NMDA receptor channel. Brain Res. 33: 61-71, 1995.
-
(1995)
Brain Res.
, vol.33
, pp. 61-71
-
-
Ikeda, K.1
Araki, K.2
Takayama, C.3
Inoue, Y.4
Yagi, T.5
Aizawa, S.6
Mishina, M.7
-
120
-
-
0030612033
-
APPsw transgenic mice develop age-related Aβ deposits and neuropil abnormalities, but no neuronal loss in CA1
-
IRIZARRY, M., M. McNAMARA, K. FEDORCHAK, K. HSIAO, AND B. HYMAN. APPsw transgenic mice develop age-related Aβ deposits and neuropil abnormalities, but no neuronal loss in CA1. J. Neuropathol. Exp. Neurol. 56: 965-973, 1997.
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 965-973
-
-
Irizarry, M.1
McNamara, M.2
Fedorchak, K.3
Hsiao, K.4
Hyman, B.5
-
121
-
-
0030611097
-
Aβ deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mice
-
IRIZARRY, M., F. SORIANO, M. McNAMARA, K. PAGE, D. SCHENK, D. GAMES, AND B. HYMAN. Aβ deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mice. J. Neurosci. 17: 7053-7059, 1997.
-
(1997)
J. Neurosci.
, vol.17
, pp. 7053-7059
-
-
Irizarry, M.1
Soriano, F.2
McNamara, M.3
Page, K.4
Schenk, D.5
Games, D.6
Hyman, B.7
-
122
-
-
0030053773
-
Age-dependent reduction of hippocampal LTP in mice lacking N-methyl-D-aspartate receptor epsilon 1 subunit
-
ITO, I., K. SAKIMURA, M. MISHINA, AND H. SUGIYAMA. Age-dependent reduction of hippocampal LTP in mice lacking N-methyl-D-aspartate receptor epsilon 1 subunit. Neurosci. Lett. 203: 69-71, 1996.
-
(1996)
Neurosci. Lett.
, vol.203
, pp. 69-71
-
-
Ito, I.1
Sakimura, K.2
Mishina, M.3
Sugiyama, H.4
-
123
-
-
0028216869
-
Synaptic vesicles and exocytosis
-
JAHN, R., AND T. C. SUDHOF. Synaptic vesicles and exocytosis. Annu. Rev. Neurosci. 17: 219-246, 1994.
-
(1994)
Annu. Rev. Neurosci.
, vol.17
, pp. 219-246
-
-
Jahn, R.1
Sudhof, T.C.2
-
124
-
-
0031465024
-
Voltage-gated and inwardly rectifying potassium channels
-
JAN, L., AND Y. JAN. Voltage-gated and inwardly rectifying potassium channels. J. Physiol (Lond.) 505: 267-282, 1997.
-
(1997)
J. Physiol (Lond.)
, vol.505
, pp. 267-282
-
-
Jan, L.1
Jan, Y.2
-
125
-
-
0030294789
-
Enhanced LTP in mice deficient in the AMPA receptor GluR2
-
JIA, Z., N. AGOPYAN, P. MIU, Z. XIONG, J. HENDERSON, R. GERLAI, F. A. TAVERNA, A. VELUMIAN, J. MACDONALD, P. CARLEN, W. ABRAMOW-NEWERLY, AND J. RODER. Enhanced LTP in mice deficient in the AMPA receptor GluR2. Neuron 17: 945-956, 1996.
-
(1996)
Neuron
, vol.17
, pp. 945-956
-
-
Jia, Z.1
Agopyan, N.2
Miu, P.3
Xiong, Z.4
Henderson, J.5
Gerlai, R.6
Taverna, F.A.7
Velumian, A.8
Macdonald, J.9
Carlen, P.10
Abramow-Newerly, W.11
Roder, J.12
-
126
-
-
16944366300
-
6-subunit gene inactivation inhibits δ-subunit expression
-
6-subunit gene inactivation inhibits δ-subunit expression. J. Neurosci. 17: 1350-1362, 1997.
-
(1997)
J. Neurosci.
, vol.17
, pp. 1350-1362
-
-
Jones, A.1
Korpi, E.2
Mckernan, R.3
Pelz, R.4
Nusser, Z.5
Makela, R.6
Mellor, J.7
Pollard, S.8
Bahn, S.9
Stephenson, F.10
Randall, A.11
Sieghart, W.12
Somogyi, P.13
Smith, A.14
Wisden, W.15
-
127
-
-
0028490884
-
Age-related fibrillar deposits in brains of C57BL/6 mice. A review of localization, staining characteristics, and strain specificity
-
JUCKER, M., L. C. WALKER, H. KUO, M. TIAN, AND D. K. INGRAM. Age-related fibrillar deposits in brains of C57BL/6 mice. A review of localization, staining characteristics, and strain specificity. Mol. Neurobiol. 9: 125-133, 1994.
-
(1994)
Mol. Neurobiol.
, vol.9
, pp. 125-133
-
-
Jucker, M.1
Walker, L.C.2
Kuo, H.3
Tian, M.4
Ingram, D.K.5
-
128
-
-
0029366767
-
A role for neurofilaments in the pathogenesis of amyotrophic lateral sclerosis
-
JULIEN, J.-P. A role for neurofilaments in the pathogenesis of amyotrophic lateral sclerosis. Biochem. Cell Biol. 73: 593-597, 1995.
-
(1995)
Biochem. Cell Biol.
, vol.73
, pp. 593-597
-
-
Julien, J.-P.1
-
129
-
-
0029812141
-
Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunit
-
KADOTANI, H., T. HIRANO, M. MASUGI, K. NAKAMURA, K. NAKAO, M. KATSUKI, AND S. NAKANISHI. Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunit. J. Neurosci. 16: 7859-7867, 1996.
-
(1996)
J. Neurosci.
, vol.16
, pp. 7859-7867
-
-
Kadotani, H.1
Hirano, T.2
Masugi, M.3
Nakamura, K.4
Nakao, K.5
Katsuki, M.6
Nakanishi, S.7
-
130
-
-
0029591742
-
Impaired synapse elimination during cerebellar development in PKC gamma mutant mice
-
KANO, M., K. HASHIMOTO, C. CHEN, A. ABELIOVICH, A. AIBA, H. KURIHARA, M. WATANABE, Y. INOUE, AND S. TONEGAWA. Impaired synapse elimination during cerebellar development in PKC gamma mutant mice. Cell 83: 1223-1231, 1995.
-
(1995)
Cell
, vol.83
, pp. 1223-1231
-
-
Kano, M.1
Hashimoto, K.2
Chen, C.3
Abeliovich, A.4
Aiba, A.5
Kurihara, H.6
Watanabe, M.7
Inoue, Y.8
Tonegawa, S.9
-
131
-
-
0031035031
-
Persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking mGluR1
-
KANO, M., K. HASHIMOTO, H. KURIHARA, M. WATANABE, Y. INOUE, A. AIBA, AND S. TONEGAWA. Persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking mGluR1. Neuron 18: 71-79, 1997.
-
(1997)
Neuron
, vol.18
, pp. 71-79
-
-
Kano, M.1
Hashimoto, K.2
Kurihara, H.3
Watanabe, M.4
Inoue, Y.5
Aiba, A.6
Tonegawa, S.7
-
133
-
-
0029023325
-
Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice
-
KASHIWABUCHI, N., K. IKEDA, K. ARAKI, T. HIRANO, K. SHIBUKI, C. TAKAYAMA, Y. INOUE, T. KUTSUWADA, T. YAGI, Y. KANG, S. AIZAWA, AND M. MISHINA. Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice. Cell 81: 245-252, 1995.
-
(1995)
Cell
, vol.81
, pp. 245-252
-
-
Kashiwabuchi, N.1
Ikeda, K.2
Araki, K.3
Hirano, T.4
Shibuki, K.5
Takayama, C.6
Inoue, Y.7
Kutsuwada, T.8
Yagi, T.9
Kang, Y.10
Aizawa, S.11
Mishina, M.12
-
134
-
-
0029995485
-
Accumulation of beta amyloid fibrils in pancreas of transgenic mice
-
KAWARABAYASHI, T., M. SHOJI, M. SATO, A. SASAKI, L. HO, C. B. ECKMAN, C. M. PRADA, S. G. YOUNKIN, T. KOBAYASHI, N. TADA, E. MATSUBARA, T. IIZUKA, Y. HARIGAYA, K. KASAI, AND S. HIRAI. Accumulation of beta amyloid fibrils in pancreas of transgenic mice. Neurobiol. Aging 17: 215-222, 1996.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 215-222
-
-
Kawarabayashi, T.1
Shoji, M.2
Sato, M.3
Sasaki, A.4
Ho, L.5
Eckman, C.B.6
Prada, C.M.7
Younkin, S.G.8
Kobayashi, T.9
Tada, N.10
Matsubara, E.11
Iizuka, T.12
Harigaya, Y.13
Kasai, K.14
Hirai, S.15
-
135
-
-
0030964708
-
A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes
-
KELLY, E., E. SANDGREN, R. BRINSTER, AND R. PALMITER. A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes. Proc. Natl. Acad. Sci. USA 94: 10045-10050, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10045-10050
-
-
Kelly, E.1
Sandgren, E.2
Brinster, R.3
Palmiter, R.4
-
137
-
-
0029763587
-
Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice
-
KISTNER, A, M. GOSSEN, F. ZIMMERMAN, J. JERECIC, C. ULLMER, H. LUBBERT, AND H. BUJARD. Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc. Natl. Acad. Sci. USA 93: 10933-10938, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10933-10938
-
-
Kistner, A.1
Gossen, M.2
Zimmerman, F.3
Jerecic, J.4
Ullmer, C.5
Lubbert, H.6
Bujard, H.7
-
138
-
-
0028858477
-
Targeted disruption of the tyrosine hydroxylase locus results in severe catecholamine depletion and perinatal lethality in mice
-
KOBAYASHI, K., S. MORITA, H. SAWADA, T. MIZUGUCHI, K. YAMADA, I. NAGATSU, T. HATA, Y. WATANABE, K. FUJITA, AND T. NAGATSU. Targeted disruption of the tyrosine hydroxylase locus results in severe catecholamine depletion and perinatal lethality in mice. J. Biol. Chem. 270: 27235-27243, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27235-27243
-
-
Kobayashi, K.1
Morita, S.2
Sawada, H.3
Mizuguchi, T.4
Yamada, K.5
Nagatsu, I.6
Hata, T.7
Watanabe, Y.8
Fujita, K.9
Nagatsu, T.10
-
139
-
-
0029962846
-
Increased startle responses in mice carrying mutations of glycine receptor subunit genes
-
KOCH, M., C. KLING, AND C. M. BECKER. Increased startle responses in mice carrying mutations of glycine receptor subunit genes. Neuroreport 7: 806-808, 1996.
-
(1996)
Neuroreport
, vol.7
, pp. 806-808
-
-
Koch, M.1
Kling, C.2
Becker, C.M.3
-
141
-
-
0026507628
-
Drugs of abuse: Anatomy, pharmacology and function of reward pathways
-
KOOB, G. F. Drugs of abuse: anatomy, pharmacology and function of reward pathways. Trends Pharmacol. Sci. 13: 177-184, 1992.
-
(1992)
Trends Pharmacol. Sci.
, vol.13
, pp. 177-184
-
-
Koob, G.F.1
-
142
-
-
13344282063
-
Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells
-
KOVACS, D., H. FAUSETT, K. PAGE, T.-W. KIM, R. MOIR, D. MERIAM, R. HOLLISTER, O. HALLMARK, R. MANCINI, K. FELSENSTEIN, B. HYMAN, R. TANZI, AND W. WASCO. Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nature Med. 2: 224-229, 1996.
-
(1996)
Nature Med.
, vol.2
, pp. 224-229
-
-
Kovacs, D.1
Fausett, H.2
Page, K.3
Kim, T.-W.4
Moir, R.5
Meriam, D.6
Hollister, R.7
Hallmark, O.8
Mancini, R.9
Felsenstein, K.10
Hyman, B.11
Tanzi, R.12
Wasco, W.13
-
144
-
-
0029155706
-
Inducible gene targeting in mice
-
KUHN, R., F. SCHWENK, M. AGUET, AND K. RAJEWSKY. Inducible gene targeting in mice. Science 269: 1427-1429, 1995.
-
(1995)
Science
, vol.269
, pp. 1427-1429
-
-
Kuhn, R.1
Schwenk, F.2
Aguet, M.3
Rajewsky, K.4
-
145
-
-
13344261412
-
Impairment of suckling response, trigeminal neuronal pattern formation and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice
-
KUTSUWADA, T., K. SAKIMURA, T. MANABE, C. TAKAYAMA, N. KATAKURA, E. KUSHIYA, R. NATSUME, M. WATANABE, Y. INOUE, T. YAGI, S. AIZAWA, M. ARAKAWA, T. TAKAHASHI, Y. NAKAMURA, H. MORI, AND M. MISHINA. Impairment of suckling response, trigeminal neuronal pattern formation and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice. Neuron 16: 333-344, 1996.
-
(1996)
Neuron
, vol.16
, pp. 333-344
-
-
Kutsuwada, T.1
Sakimura, K.2
Manabe, T.3
Takayama, C.4
Katakura, N.5
Kushiya, E.6
Natsume, R.7
Watanabe, M.8
Inoue, Y.9
Yagi, T.10
Aizawa, S.11
Arakawa, M.12
Takahashi, T.13
Nakamura, Y.14
Mori, H.15
Mishina, M.16
-
146
-
-
0029977337
-
Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis/riluzole group II
-
LACOMBLEZ, L., G. BENSIMON, P. LEIGH, P. GUILLET, AND V. MEININGER. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis/riluzole group II. Lancet 347: 1425-1432, 1996.
-
(1996)
Lancet
, vol.347
, pp. 1425-1432
-
-
Lacomblez, L.1
Bensimon, G.2
Leigh, P.3
Guillet, P.4
Meininger, V.5
-
147
-
-
0029823454
-
Extracellular deposition of β-amyloid upon p53-dependent neuronal cell death in transgenic mice
-
LAFERLA, F., C. KAPPEL HALL, L. NGO, AND G. JAY. Extracellular deposition of β-amyloid upon p53-dependent neuronal cell death in transgenic mice. J. Clin. Invest. 98: 1626-1632, 1996.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1626-1632
-
-
Laferla, F.1
Kappel Hall, C.2
Ngo, L.3
Jay, G.4
-
148
-
-
0028981717
-
The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice
-
LAFERLA, F., B. TINKLE, C. BIEBERICH, C. HAUDENSCHILD, AND G. JAY. The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nature Genet. 9: 21-30, 1995.
-
(1995)
Nature Genet.
, vol.9
, pp. 21-30
-
-
Laferla, F.1
Tinkle, B.2
Bieberich, C.3
Haudenschild, C.4
Jay, G.5
-
149
-
-
0031031120
-
Presenilins, amyloid-beta and Alzheimer's disease
-
LAMB, B. Presenilins, amyloid-beta and Alzheimer's disease. Nature Med. 3: 28-29, 1997.
-
(1997)
Nature Med.
, vol.3
, pp. 28-29
-
-
Lamb, B.1
-
150
-
-
0027242091
-
Introduction and expression of the 400 kilobase precursor amyloid protein in transgenic mice
-
LAMB, B., S. SISODIA, A. LAWLER, H. SLUNT, C. KITT, W. KEARNS, P. PEARSON, D. PRICE, AND J. GEARHART. Introduction and expression of the 400 kilobase precursor amyloid protein in transgenic mice. Nature Genet. 5: 22-29, 1993.
-
(1993)
Nature Genet.
, vol.5
, pp. 22-29
-
-
Lamb, B.1
Sisodia, S.2
Lawler, A.3
Slunt, H.4
Kitt, C.5
Kearns, W.6
Pearson, P.7
Price, D.8
Gearhart, J.9
-
151
-
-
0028266881
-
Analysis of behavioral and hippocampal variation in congenic albino and pigmented BALB mice
-
LASSALLE, J. M., H. HALLEY, AND P. ROULLET. Analysis of behavioral and hippocampal variation in congenic albino and pigmented BALB mice. Behav. Genet. 24: 161-169, 1994.
-
(1994)
Behav. Genet.
, vol.24
, pp. 161-169
-
-
Lassalle, J.M.1
Halley, H.2
Roullet, P.3
-
152
-
-
0028111166
-
Analysing brain function and dysfunction in transgenic animals
-
LATHE, R., AND R. MORRIS. Analysing brain function and dysfunction in transgenic animals. Neuropathol. Appl. Neurobiol. 20: 350-358, 1994.
-
(1994)
Neuropathol. Appl. Neurobiol.
, vol.20
, pp. 350-358
-
-
Lathe, R.1
Morris, R.2
-
153
-
-
0026480841
-
Eight-arm maze performance, neophobia, and hippocampal cholinergic alterations after prenatal oxazepam in mice
-
LAVIOLA, G., C. G. PICK, J. YANAI, AND E. ALLEVA. Eight-arm maze performance, neophobia, and hippocampal cholinergic alterations after prenatal oxazepam in mice. Brain Res. Bull. 29: 609-616, 1992.
-
(1992)
Brain Res. Bull.
, vol.29
, pp. 609-616
-
-
Laviola, G.1
Pick, C.G.2
Yanai, J.3
Alleva, E.4
-
154
-
-
0029095907
-
The cyclic AMP response element directs tyrosine hydroxylase expression in catecholaminergic central and peripheral nervous system cell lines from transgenic mice
-
LAZAROFF, M., S. PATANKAR, S. O. YOON, AND D. M. CHIKARAISHI. The cyclic AMP response element directs tyrosine hydroxylase expression in catecholaminergic central and peripheral nervous system cell lines from transgenic mice. J. Biol. Chem. 270: 21579-21589, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21579-21589
-
-
Lazaroff, M.1
Patankar, S.2
Yoon, S.O.3
Chikaraishi, D.M.4
-
155
-
-
0030841177
-
Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor
-
LEDENT, C., J. M. VAUGEOIS, S. N. SCHIFFMANN, T. PEDRAZZINI, M. EL YACOUBI, J. J. VANDERHAEGHEN, J. COSTENTIN, J. K. HEATH, G. VASSART, AND M. PARMENTIER. Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor. Nature 388: 674-678, 1997.
-
(1997)
Nature
, vol.388
, pp. 674-678
-
-
Ledent, C.1
Vaugeois, J.M.2
Schiffmann, S.N.3
Pedrazzini, T.4
Yacoubi, M.E.L.5
Vanderhaeghen, J.J.6
Costentin, J.7
Heath, J.K.8
Vassart, G.9
Parmentier, M.10
-
156
-
-
0030273627
-
Transgenic models of neurodegenerative diseases
-
LEE, M., D. BORCHELT, P. WONG, S. SISODIA, AND D. PRICE. Transgenic models of neurodegenerative diseases. Curr. Opin. Neurobiol. 6: 651-660, 1996.
-
(1996)
Curr. Opin. Neurobiol.
, vol.6
, pp. 651-660
-
-
Lee, M.1
Borchelt, D.2
Wong, P.3
Sisodia, S.4
Price, D.5
-
157
-
-
0028116467
-
A mutant neurofilament subunit causes massive, selective motor neuron death: Implications for the pathogenesis of human motor neuron disease
-
LEE, M., J. MARSZALEK, AND D. CLEVELAND. A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease. Neuron 13: 975-988, 1994.
-
(1994)
Neuron
, vol.13
, pp. 975-988
-
-
Lee, M.1
Marszalek, J.2
Cleveland, D.3
-
158
-
-
0026602808
-
Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene
-
LE MOUELLIC, H., Y. LALLEMAND, AND P. BRULET. Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene. Cell 69: 251-264, 1992.
-
(1992)
Cell
, vol.69
, pp. 251-264
-
-
Le Mouellic, H.1
Lallemand, Y.2
Brulet, P.3
-
159
-
-
0028141417
-
Working memory performance and cholinergic effects in the ventral tegmental area and substantia nigra
-
LEVIN, E. D., S. J. BRIGGS, N. C. CHRISTOPHER, AND J. T. AUMAN. Working memory performance and cholinergic effects in the ventral tegmental area and substantia nigra. Brain Res. 657: 165-170, 1994.
-
(1994)
Brain Res.
, vol.657
, pp. 165-170
-
-
Levin, E.D.1
Briggs, S.J.2
Christopher, N.C.3
Auman, J.T.4
-
160
-
-
0028173680
-
Whisker-related neuronal patterns fail to develop in the trigeminal brain stem nuclei of NMDAR1 knockout mice
-
LI, Y., R. S. ERZURUMLU, C. CHEN, S. JHAVERI, AND S. TONEGAWA. Whisker-related neuronal patterns fail to develop in the trigeminal brain stem nuclei of NMDAR1 knockout mice. Cell 76: 427-437, 1994.
-
(1994)
Cell
, vol.76
, pp. 427-437
-
-
Li, Y.1
Erzurumlu, R.S.2
Chen, C.3
Jhaveri, S.4
Tonegawa, S.5
-
161
-
-
0028785516
-
Studies on the influence of cytosin methylation on DNA recombination and end-joining in mammalian cells
-
LIANG, F., AND M. JASIN. Studies on the influence of cytosin methylation on DNA recombination and end-joining in mammalian cells. J. Biol. Chem. 270: 23838-23844, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23838-23844
-
-
Liang, F.1
Jasin, M.2
-
162
-
-
0029938431
-
Rational design of an animal model for Alzheimer's disease: Introduction of multiple human genomic transgenes to reproduce pathology in a rodent
-
LORING J., C. PASZTY, A. ROSE, T. MCINTOSH, H. MURAI, J. PIERCE, S. SCHRAMM, K. WYMORE, V.-Y. LEE, J. TROJANOWSKI, AND K. PETERSON. Rational design of an animal model for Alzheimer's disease: introduction of multiple human genomic transgenes to reproduce pathology in a rodent. Neurobiol. Aging 17: 173-182, 1996.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 173-182
-
-
Loring, J.1
Paszty, C.2
Rose, A.3
Mcintosh, T.4
Murai, H.5
Pierce, J.6
Schramm, S.7
Wymore, K.8
Lee, V.-Y.9
Trojanowski, J.10
Peterson, K.11
-
163
-
-
0025194985
-
A receptor selective for a behavioural alcohol antagonist
-
A receptor selective for a behavioural alcohol antagonist. Nature 346: 648-651, 1990.
-
(1990)
Nature
, vol.346
, pp. 648-651
-
-
Luddens, H.1
Pritchett, D.B.2
Kohler, M.3
Killisch, I.4
Keinanen, K.5
Monyer, H.6
Sprengel, R.7
Seeburg, P.H.8
-
164
-
-
0029731654
-
Animal models for motor neuron diseases: Research directions
-
LUDOLPH, A. Animal models for motor neuron diseases: research directions. Neurology 47, Suppl: S228-S232, 1996.
-
(1996)
Neurology
, vol.47
, Issue.SUPPL.
-
-
Ludolph, A.1
-
165
-
-
0039357820
-
+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons
-
+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons. Neuron 19: 687-695, 1997.
-
(1997)
Neuron
, vol.19
, pp. 687-695
-
-
Luscher, C.1
Jan, L.2
Stoffel, M.3
Malenka, R.4
Nicoll, R.5
-
167
-
-
0029764770
-
Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB
-
MALDONADO, R., J. A. BLENDY, E. TZAVARA, P. GASS, B. P. ROQUES, J. HANOUNE, AND G. SCHUTZ. Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB. Science 273: 657-659, 1996.
-
(1996)
Science
, vol.273
, pp. 657-659
-
-
Maldonado, R.1
Blendy, J.A.2
Tzavara, E.3
Gass, P.4
Roques, B.P.5
Hanoune, J.6
Schutz, G.7
-
169
-
-
0027941257
-
Synaptic plasticity in the hippocampus: LTP and LTD
-
MALENKA, R. Synaptic plasticity in the hippocampus: LTP and LTD. Cell 78: 535-538, 1994.
-
(1994)
Cell
, vol.78
, pp. 535-538
-
-
Malenka, R.1
-
170
-
-
0029954289
-
Lack of β-amyloidosis in transgenic mice expressing low levels of familial Alzheimer's disease missense mutations
-
MALHERBE, P., J. RICHARDS, J. MARTIN, H. BLUETHMANN, J. MAGGIO, AND G. HUBER. Lack of β-amyloidosis in transgenic mice expressing low levels of familial Alzheimer's disease missense mutations. Neurobiol. Aging 17: 205-214, 1996.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 205-214
-
-
Malherbe, P.1
Richards, J.2
Martin, J.3
Bluethmann, H.4
Maggio, J.5
Huber, G.6
-
171
-
-
0027368451
-
Modulation of synaptic transmission and long-term potentiation: Effects on paired-pulse facilitation and EPSC variance in the CA1 region of the hippocampus
-
MANABE, T., D. WYLLIE, D. PERKEL, AND R. NICOLL. Modulation of synaptic transmission and long-term potentiation: effects on paired-pulse facilitation and EPSC variance in the CA1 region of the hippocampus. J. Neurophysiol. 70: 1451-1459, 1993.
-
(1993)
J. Neurophysiol.
, vol.70
, pp. 1451-1459
-
-
Manabe, T.1
Wyllie, D.2
Perkel, D.3
Nicoll, R.4
-
172
-
-
0028051345
-
Tau protein and Alzheimer's disease
-
MANDELKOW, E.-M., AND E. MANDELKOW. Tau protein and Alzheimer's disease. Neurobiol. Aging 15, Suppl.: S85-S86, 1994.
-
(1994)
Neurobiol. Aging
, vol.15
, Issue.SUPPL.
-
-
Mandelkow, E.-M.1
Mandelkow, E.2
-
173
-
-
0032498227
-
Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory
-
MANSUY, I. M., M. MAYFORD, B. JACOB, E. R. KANDEL, AND M. E. BACH. Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory. Cell 92: 39-49, 1998.
-
(1998)
Cell
, vol.92
, pp. 39-49
-
-
Mansuy, I.M.1
Mayford, M.2
Jacob, B.3
Kandel, E.R.4
Bach, M.E.5
-
175
-
-
0029813177
-
Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β-amyloid precursor protein and Alzheimer's disease
-
MASLIAH, E., A. SISK, M. MALLORY, L. MUCKE, D. SCHENK, AND D. GAMES. Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β-amyloid precursor protein and Alzheimer's disease. J. Neurosci. 16: 5795-5811, 1996.
-
(1996)
J. Neurosci.
, vol.16
, pp. 5795-5811
-
-
Masliah, E.1
Sisk, A.2
Mallory, M.3
Mucke, L.4
Schenk, D.5
Games, D.6
-
176
-
-
0028937683
-
Specific deficit of the on response in visual transmission by targeted disruption of the mGluR6 gene
-
MASU, M., H. IWAKABE, Y. TAGAWA, T. MIYOSHI, M. YAMASHITA, Y. FUKUDA, H. SASAKI, K. HIROI, Y. NAKAMURA, R. SHIGEMOTO, M. TAKADA, K. NAKAMURA, K. NAKAO, M. KATSUKI, AND S. NAKANISHI. Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell 80: 757-765, 1995.
-
(1995)
Cell
, vol.80
, pp. 757-765
-
-
Masu, M.1
Iwakabe, H.2
Tagawa, Y.3
Miyoshi, T.4
Yamashita, M.5
Fukuda, Y.6
Sasaki, H.7
Hiroi, K.8
Nakamura, Y.9
Shigemoto, R.10
Takada, M.11
Nakamura, K.12
Nakao, K.13
Katsuki, M.14
Nakanishi, S.15
-
177
-
-
0027305627
-
Expression of the rat calmodulin gene II in the central nervous system: A 294-base promoter and 68-base leader segment mediates neuron-specific gene expression in transgenic mice
-
MATSUO, K., H. IKESHIMA, K. SHIMODA, A. UMEZAWA, J. HATA, K. MAEJIMA, H. NOJIMA, AND T. TAKANO. Expression of the rat calmodulin gene II in the central nervous system: a 294-base promoter and 68-base leader segment mediates neuron-specific gene expression in transgenic mice. Brain Res. 20: 9-20, 1993.
-
(1993)
Brain Res.
, vol.20
, pp. 9-20
-
-
Matsuo, K.1
Ikeshima, H.2
Shimoda, K.3
Umezawa, A.4
Hata, J.5
Maejima, K.6
Nojima, H.7
Takano, T.8
-
178
-
-
0029852678
-
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene
-
MATTHES, H. W., R. MALDONADO, F. SIMONIN, O. VALVERDE, S. SLOWE, I. KITCHEN, K. BEFORT, A. DIERICH, M. LE MEUR, P. DOLLE, E. TZAVARA, J. HANOUNE, B. P. ROQUES, AND B. L. KIEFFER. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature 383: 819-823, 1996.
-
(1996)
Nature
, vol.383
, pp. 819-823
-
-
Matthes, H.W.1
Maldonado, R.2
Simonin, F.3
Valverde, O.4
Slowe, S.5
Kitchen, I.6
Befort, K.7
Dierich, A.8
Meur, M.L.E.9
Dolle, P.10
Tzavara, E.11
Hanoune, J.12
Roques, B.P.13
Kieffer, B.L.14
-
180
-
-
0029807527
-
Control of memory formation through regulated expression of a CaMKII transgene
-
MAYFORD, M., M. E. BACH, Y. Y. HUANG, L. WANG, R. D. HAWKINS, AND E. R. KANDEL. Control of memory formation through regulated expression of a CaMKII transgene. Science 274: 1678-1683, 1996.
-
(1996)
Science
, vol.274
, pp. 1678-1683
-
-
Mayford, M.1
Bach, M.E.2
Huang, Y.Y.3
Wang, L.4
Hawkins, R.D.5
Kandel, E.R.6
-
181
-
-
0029066116
-
CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP
-
MAYFORD, M., J. WANG, E. R. KANDEL, AND T. J. O'DELL. CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell 81: 891-904, 1995.
-
(1995)
Cell
, vol.81
, pp. 891-904
-
-
Mayford, M.1
Wang, J.2
Kandel, E.R.3
O'Dell, T.J.4
-
182
-
-
15844382546
-
Targeted deletion in astrocyte intermediate filament (Gfap) alters neuronal physiology
-
MCCALL, M. A., R. G. GREGG, R. R. BEHRINGER, M. BRENNER, C. L. DELANEY, E. J. GALBREATH, C. L. ZHANG, R. A. PEARCE, S. Y. CHIU, AND A. MESSING. Targeted deletion in astrocyte intermediate filament (Gfap) alters neuronal physiology. Proc. Natl. Acad. Sci. USA 93: 6361-6366, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6361-6366
-
-
Mccall, M.A.1
Gregg, R.G.2
Behringer, R.R.3
Brenner, M.4
Delaney, C.L.5
Galbreath, E.J.6
Zhang, C.L.7
Pearce, R.A.8
Chiu, S.Y.9
Messing, A.10
-
183
-
-
0030475008
-
Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice
-
MCHUGH, T. J., K. I. BLUM, J. Z. TSIEN, S. TONEGAWA, AND M. A. WILSON. Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice. Cell 87: 1339-1349, 1996.
-
(1996)
Cell
, vol.87
, pp. 1339-1349
-
-
MCHUGH, T.J.1
Blum, K.I.2
Tsien, J.Z.3
Tonegawa, S.4
Wilson, M.A.5
-
184
-
-
3643062201
-
Preparing neural tissues for metabolic study in vitro
-
edited by R. R. H MCIlwain. London: Churchill
-
MCILWAIN, H., AND R. RODNIGHT. Preparing neural tissues for metabolic study in vitro. In: Practical Neurochemistry, edited by R. R. H MCIlwain. London: Churchill, 1962, p. 109-133.
-
(1962)
Practical Neurochemistry
, pp. 109-133
-
-
Mcilwain, H.1
Rodnight, R.2
-
185
-
-
0030671407
-
ATP channel
-
ATP channel. Proc. Natl. Acad. Sci. USA 94: 11969-11973, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11969-11973
-
-
Miki, T.1
Tashiro, F.2
Iwanaga, T.3
Nagashima, K.4
Yoshitomi, H.5
Aihara, H.6
Nitta, Y.7
Gonoi, T.8
Inagaki, N.9
Miyazaki, J.-I.10
Seino, S.11
-
186
-
-
0029622329
-
Retained cocaine conditioned place preference in D1 receptor deficient mice
-
MINER, L. L., J. DRAGO, P. M. CHAMBERLAIN, D. DONOVAN, AND G. R. UHL. Retained cocaine conditioned place preference in D1 receptor deficient mice. Neuroreport 6: 2314-2316, 1995.
-
(1995)
Neuroreport
, vol.6
, pp. 2314-2316
-
-
Miner, L.L.1
Drago, J.2
Chamberlain, P.M.3
Donovan, D.4
Uhl, G.R.5
-
187
-
-
0029591819
-
Assessment of a mutation in the H5 domain of GIRK2 as a candidate for the weaver mutation
-
MJAATVEDT, A., D. CABIN, S. COLE, L. LONG, G. BREITWIESER, AND R. REEVES. Assessment of a mutation in the H5 domain of GIRK2 as a candidate for the weaver mutation. Genome Res. 5: 453-463, 1995.
-
(1995)
Genome Res.
, vol.5
, pp. 453-463
-
-
Mjaatvedt, A.1
Cabin, D.2
Cole, S.3
Long, L.4
Breitwieser, G.5
Reeves, R.6
-
188
-
-
0026317875
-
Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting
-
MOMBAERTS, P., A. R. CLARKE, M. L. HOOPER, AND S. TONEGAWA. Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting. Proc. Natl. Acad. Sci. USA 88: 3084-3087, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 3084-3087
-
-
Mombaerts, P.1
Clarke, A.R.2
Hooper, M.L.3
Tonegawa, S.4
-
189
-
-
0028474199
-
YACs, BACs, PACs, and MACs: Artificial chromosomes as research tools
-
MONACO, A., AND Z. LARIN. YACs, BACs, PACs, and MACs: artificial chromosomes as research tools. Trends Biotechnol. 12: 280-286, 1994.
-
(1994)
Trends Biotechnol.
, vol.12
, pp. 280-286
-
-
Monaco, A.1
Larin, Z.2
-
190
-
-
0029055738
-
Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of the human β-amyloid precursor protein
-
MORAN, P., L. HIGGINS, B. CORDELL, AND P. MOSER. Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of the human β-amyloid precursor protein. Proc. Natl. Acad. Sci. USA 92: 5341-5345, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5341-5345
-
-
Moran, P.1
Higgins, L.2
Cordell, B.3
Moser, P.4
-
191
-
-
0029856343
-
Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor
-
MORATALLA, R., M. XU, S. TONEGAWA, AND A. M. GRAYBIEL. Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor. Proc. Natl. Acad. Sci. USA 93: 14928-14933, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14928-14933
-
-
Moratalla, R.1
Xu, M.2
Tonegawa, S.3
Graybiel, A.M.4
-
192
-
-
0027340250
-
Gi alpha 2 mediates the inhibitory regulation of adenylyl cyclase in vivo: Analysis in transgenic mice with Gi alpha 2 suppressed by inducible antisense RNA. Dev
-
MOXHAM, C., Y. HOD, AND C. MALBON. Gi alpha 2 mediates the inhibitory regulation of adenylyl cyclase in vivo: analysis in transgenic mice with Gi alpha 2 suppressed by inducible antisense RNA. Dev. Genet. 14: 266-273, 1993.
-
(1993)
Genet.
, vol.14
, pp. 266-273
-
-
Moxham, C.1
Hod, Y.2
Malbon, C.3
-
193
-
-
0027249144
-
Induction of G alpha i2-specific antisense RNA in vivo inhibits neonatal growth
-
MOXHAM, C., Y. HOD, AND C. MALBON. Induction of G alpha i2-specific antisense RNA in vivo inhibits neonatal growth. Science 260: 991-995, 1993.
-
(1993)
Science
, vol.260
, pp. 991-995
-
-
Moxham, C.1
Hod, Y.2
Malbon, C.3
-
194
-
-
0029924264
-
Neurotrophic and neuroprotective effects of hAPP in transgenic mice
-
MUCKE, L., C. ABRAHAM, AND E. MASLIAH. Neurotrophic and neuroprotective effects of hAPP in transgenic mice. Ann. NY Acad. Sci. 777: 82-88, 1996.
-
(1996)
Ann. NY Acad. Sci.
, vol.777
, pp. 82-88
-
-
Mucke, L.1
Abraham, C.2
Masliah, E.3
-
195
-
-
0027422751
-
Genetic and molecular advances in Alzheimer's disease
-
MULLAN, M., AND F. CRAWFORD. Genetic and molecular advances in Alzheimer's disease. Trends Neurosci. 16: 398-403, 1993.
-
(1993)
Trends Neurosci.
, vol.16
, pp. 398-403
-
-
Mullan, M.1
Crawford, F.2
-
196
-
-
0029397107
-
Molecular inactivation. Spatially and temporally defined molecular knockouts
-
MULLER, B. K., AND F. BONHOEFFER. Molecular inactivation. Spatially and temporally defined molecular knockouts. Curr. Biol. 5: 1255-1256, 1995.
-
(1995)
Curr. Biol.
, vol.5
, pp. 1255-1256
-
-
Muller, B.K.1
Bonhoeffer, F.2
-
197
-
-
0024412495
-
Molecular biology of Alzheimer's disease
-
MULLER, H., AND K. BEYREUTHER. Molecular biology of Alzheimer's disease. Annu. Rev. Biochem. 58: 287-307, 1989.
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 287-307
-
-
Muller, H.1
Beyreuther, K.2
-
198
-
-
0028018919
-
Behavioral and anatomical defects in mice homozygous for a modified β-amyloid precursor protein gene
-
MULLER, U., N. CRISTINA, Z.-W. LI, D. WOLFER, H.-P. LIPP, T. RULICKE, S. BRANDNER, A. AGUZZI, AND C. WEISSMANN. Behavioral and anatomical defects in mice homozygous for a modified β-amyloid precursor protein gene. Cell 79: 755-765, 1994.
-
(1994)
Cell
, vol.79
, pp. 755-765
-
-
Muller, U.1
Cristina, N.2
Li, Z.-W.3
Wolfer, D.4
Lipp, H.-P.5
Rulicke, T.6
Brandner, S.7
Aguzzi, A.8
Weissmann, C.9
-
199
-
-
0030861479
-
An immunocytochemical study on the distribution of two G-protein-gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain
-
MURER, G., C. ADELBRECHT, I. LAURITZEN, F. LESAGE, M. LAZDUNSKI, Y. AGID, AND R. RAISMAN-VOZARI. An immunocytochemical study on the distribution of two G-protein-gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain. Neuroscience 80: 345-357, 1997.
-
(1997)
Neuroscience
, vol.80
, pp. 345-357
-
-
Murer, G.1
Adelbrecht, C.2
Lauritzen, I.3
Lesage, F.4
Lazdunski, M.5
Agid, Y.6
Raisman-Vozari, R.7
-
200
-
-
0015632921
-
Influence of genotype and neonatal irradiation upon open-field locomotion and elimination in mice
-
NASH, D. J. Influence of genotype and neonatal irradiation upon open-field locomotion and elimination in mice. J. Comp. Physiol. Psychol. 83: 458-464, 1973.
-
(1973)
J. Comp. Physiol. Psychol.
, vol.83
, pp. 458-464
-
-
Nash, D.J.1
-
201
-
-
0029791355
-
Huntington disease: New insights into the relationship between CAG expansion and disease
-
NASIR, J., Y. GOLDBERG, AND M. HAYDEN. Huntington disease: new insights into the relationship between CAG expansion and disease. Hum. Mol. Genet. 5: 1431-1435, 1996.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1431-1435
-
-
Nasir, J.1
Goldberg, Y.2
Hayden, M.3
-
203
-
-
0030219026
-
The genetic basis of neuromuscular disorders
-
NAWROTZKI, R., D. J. BLAKE, AND K. E. DAVIES. The genetic basis of neuromuscular disorders. Trends Genet. 12: 294-298, 1996.
-
(1996)
Trends Genet.
, vol.12
, pp. 294-298
-
-
Nawrotzki, R.1
Blake, D.J.2
Davies, K.E.3
-
204
-
-
0029093566
-
Contrasting properties of two forms of long-term potentiation in the hippocampus
-
NICOLL, R., AND R. MALENKA. Contrasting properties of two forms of long-term potentiation in the hippocampus. Nature 377: 115-118, 1995.
-
(1995)
Nature
, vol.377
, pp. 115-118
-
-
Nicoll, R.1
Malenka, R.2
-
205
-
-
0029865151
-
Ecdysone-inducible gene expression in mammalian cells and transgenic mice
-
NO, D., T.-P. YAO, AND R. EVANS. Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Genetics 93: 3346-3351, 1996.
-
(1996)
Genetics
, vol.93
, pp. 3346-3351
-
-
No, D.1
Yao, T.-P.2
Evans, R.3
-
206
-
-
0024730134
-
Drug receptors and the inhibition of nerve cells
-
NORTH, R. Drug receptors and the inhibition of nerve cells. Br. J. Pharmacol. 98: 13-28, 1989.
-
(1989)
Br. J. Pharmacol.
, vol.98
, pp. 13-28
-
-
North, R.1
-
207
-
-
13344282736
-
Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1
-
NOSTEN-BERTRAND, M., M. L. ERRINGTON, K. P. MURPHY, Y. TOKUGAWA, E. BARBONI, E. KOZLOVA, D. MICHALOVICH, R. G. MORRIS, J. SILVER, C. L. STEWART, T. V. BLISS, AND R. J. MORRIS. Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1. Nature 379: 826-829, 1996.
-
(1996)
Nature
, vol.379
, pp. 826-829
-
-
Nosten-Bertrand, M.1
Errington, M.L.2
Murphy, K.P.3
Tokugawa, Y.4
Barboni, E.5
Kozlova, E.6
Michalovich, D.7
Morris, R.G.8
Silver, J.9
Stewart, C.L.10
Bliss, T.V.11
Morris, R.J.12
-
208
-
-
0013973190
-
Effects of mecamylamine on avoidance conditioning and maze learning of mice
-
OLIVERIO, A. Effects of mecamylamine on avoidance conditioning and maze learning of mice. J. Pharmacol. Exp. Ther. 154: 350-356, 1966.
-
(1966)
J. Pharmacol. Exp. Ther.
, vol.154
, pp. 350-356
-
-
Oliverio, A.1
-
209
-
-
0026764280
-
Tissue- and site-specific DNA recombination in transgenic mice
-
ORBAN, P., D. CHUI, AND J. MARTH. Tissue- and site-specific DNA recombination in transgenic mice. Proc. Natl. Acad. Sci. USA 89: 6861-6865, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6861-6865
-
-
Orban, P.1
Chui, D.2
Marth, J.3
-
210
-
-
0028796049
-
Evolutionary history of the ligand-gated ion-channel superfamily of receptors
-
ORTELLS, M., AND G. LUNT. Evolutionary history of the ligand-gated ion-channel superfamily of receptors. Trends Neurosci. 18: 121-127, 1995.
-
(1995)
Trends Neurosci.
, vol.18
, pp. 121-127
-
-
Ortells, M.1
Lunt, G.2
-
211
-
-
0029115971
-
A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation
-
PATIL, N., D. COX, D. BHAT, M. FAHAM, R. MYERS, AND A. PETERSON. A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation. Nature Genet. 11: 126-129, 1995.
-
(1995)
Nature Genet.
, vol.11
, pp. 126-129
-
-
Patil, N.1
Cox, D.2
Bhat, D.3
Faham, M.4
Myers, R.5
Peterson, A.6
-
212
-
-
0029814483
-
Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor
-
PEKHLETSKI, R., R. GERLAI, L. S. OVERSTREET, X. P. HUANG, N. AGOPYAN, N. T. SLATER, W. ABRAMOW-NEWERLY, J. C. RODER, AND D. R. HAMPSON. Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor. J. Neurosci. 16: 6364-6373, 1996.
-
(1996)
J. Neurosci.
, vol.16
, pp. 6364-6373
-
-
Pekhletski, R.1
Gerlai, R.2
Overstreet, L.S.3
Huang, X.P.4
Agopyan, N.5
Slater, N.T.6
Abramow-Newerly, W.7
Roder, J.C.8
Hampson, D.R.9
-
213
-
-
0031081136
-
Production of transgenic mice with yeast artificial chromosomes
-
PETERSON, K., C. CLEGG, Q. LI, AND G. STAMATOYANNOPOULOS. Production of transgenic mice with yeast artificial chromosomes. Trends Genet. 13: 61-66, 1997.
-
(1997)
Trends Genet.
, vol.13
, pp. 61-66
-
-
Peterson, K.1
Clegg, C.2
Li, Q.3
Stamatoyannopoulos, G.4
-
214
-
-
0028178796
-
B receptor-mediated inhibition of calcium currents and excitatory synaptic transmission in hippocampal neurons in vitro
-
B receptor-mediated inhibition of calcium currents and excitatory synaptic transmission in hippocampal neurons in vitro. Neuron 12: 97-107, 1994.
-
(1994)
Neuron
, vol.12
, pp. 97-107
-
-
Pfrieger, F.1
Gottmann, K.2
Lux, H.3
-
215
-
-
17144413330
-
Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain
-
PICCIOTTO, M. R., M. ZOLI, C. LENA, A. BESSIS, Y. LALLEMAND, N. LENOVERE, P. VINCENT, E. M. PICH, P. BRULET, AND J. P. CHANGEUX. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature 374: 65-67, 1995.
-
(1995)
Nature
, vol.374
, pp. 65-67
-
-
Picciotto, M.R.1
Zoli, M.2
Lena, C.3
Bessis, A.4
Lallemand, Y.5
Lenovere, N.6
Vincent, P.7
Pich, E.M.8
Brulet, P.9
Changeux, J.P.10
-
216
-
-
0032495515
-
2-subunit are involved in the reinforcing properties of nicotine
-
2-subunit are involved in the reinforcing properties of nicotine. Nature 391: 173-177, 1998.
-
(1998)
Nature
, vol.391
, pp. 173-177
-
-
Picciotto, M.R.1
Zoli, M.2
Rimondini, R.3
Léna, C.4
Marubio, L.M.5
Merlo Pich, E.6
Fuxe, K.7
Changeux, J.P.8
-
217
-
-
0024477606
-
A receptor subunit for benzodiazepine pharmacology
-
A receptor subunit for benzodiazepine pharmacology. Nature 338: 582-585, 1989.
-
(1989)
Nature
, vol.338
, pp. 582-585
-
-
Pritchett, D.B.1
Sontheimer, H.2
Shivers, B.D.3
Ymer, S.4
Kettenmann, H.5
Schofield, P.R.6
Seeburg, P.H.7
-
218
-
-
0030822582
-
Prion diseases and the BSE crisis
-
PRUSINER, S. Prion diseases and the BSE crisis. Science 278: 245-251, 1997.
-
(1997)
Science
, vol.278
, pp. 245-251
-
-
Prusiner, S.1
-
219
-
-
0028812670
-
Recognition and alignment of homologous DNA sequences between minichromosomes and single stranded DNA promoted by RecA protein
-
RAMDAS, J., AND K. MUNIYAPPA. Recognition and alignment of homologous DNA sequences between minichromosomes and single stranded DNA promoted by RecA protein. Mol. Gen. Genet. 249: 336-348, 1995.
-
(1995)
Mol. Gen. Genet.
, vol.249
, pp. 336-348
-
-
Ramdas, J.1
Muniyappa, K.2
-
220
-
-
15844393658
-
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
-
REAUME, A., J. ELLIOT, E. HOFFMAN, N. KOWALL, R. FERRANTE, D. SIWEK, H. WILCOX, D. FLOOD, M. BEAL, R. J. BROWN, R. SCOTT, AND W. SNIDER. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nature Genet. 13: 43-47, 1996.
-
(1996)
Nature Genet.
, vol.13
, pp. 43-47
-
-
Reaume, A.1
Elliot, J.2
Hoffman, E.3
Kowall, N.4
Ferrante, R.5
Siwek, D.6
Wilcox, H.7
Flood, D.8
Beal, M.9
Brown, R.J.10
Scott, R.11
Snider, W.12
-
221
-
-
0029788661
-
Enhanced amyloidogenic processing of the β-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Aβ sequence
-
REAUME, A., D. HOWLAND, S. TRUSKO, M. SAVAGE, D. LANG, B. GREENBERG, R. SIMAN, AND R. SCOTT. Enhanced amyloidogenic processing of the β-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Aβ sequence. J. Biol. Chem. 271: 23380-23388, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23380-23388
-
-
Reaume, A.1
Howland, D.2
Trusko, S.3
Savage, M.4
Lang, D.5
Greenberg, B.6
Siman, R.7
Scott, R.8
-
222
-
-
0028337533
-
Astrocytosis and axonal proliferation in the hippocampus of S100β transgenic mice
-
REEVES, R., J. YAO, M. CROWLEY, S. BUCK, X. ZHANG, P. YAROWSKI, J. GEARHART, AND D. HILT. Astrocytosis and axonal proliferation in the hippocampus of S100β transgenic mice. Proc. Natl. Acad. Sci. USA 91: 5359-5363, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5359-5363
-
-
Reeves, R.1
Yao, J.2
Crowley, M.3
Buck, S.4
Zhang, X.5
Yarowski, P.6
Gearhart, J.7
Hilt, D.8
-
223
-
-
85044498575
-
Molar characteristics of exploratory and investigatory behavior in the rat (Rattus norvegicus)
-
RENNER, M. J., AND C. P. SELTZER. Molar characteristics of exploratory and investigatory behavior in the rat (Rattus norvegicus). J. Comp. Psychol. 105: 326-339, 1991.
-
(1991)
J. Comp. Psychol.
, vol.105
, pp. 326-339
-
-
Renner, M.J.1
Seltzer, C.P.2
-
224
-
-
0027768980
-
Cholinergic drugs regulate passive avoidance performance via the amygdala
-
RIEKKINEN, P., JR., M. RIEKKINEN, AND J. SIRVIO. Cholinergic drugs regulate passive avoidance performance via the amygdala. J. Pharmacol. Exp. Ther. 267: 1484-1492, 1993.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.267
, pp. 1484-1492
-
-
Riekkinen Jr., P.1
Riekkinen, M.2
Sirvio, J.3
-
225
-
-
0028888945
-
Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
-
RIPPS, M., G. HUNTLEY, P. HOF, J. MORRISON, AND J. GORDON. Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA 92: 689-693, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 689-693
-
-
Ripps, M.1
Huntley, G.2
Hof, P.3
Morrison, J.4
Gordon, J.5
-
226
-
-
0028875687
-
Levels and alternative splicing of amyloid β protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease
-
ROCKENSTEIN, E., L. MCCONLOGUE, H. TAN, M. POWER, E. MASLIAH, AND L. MUCKE. Levels and alternative splicing of amyloid β protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease. J. Biol. Chem. 270: 28257-28267, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28257-28267
-
-
Rockenstein, E.1
Mcconlogue, L.2
Tan, H.3
Power, M.4
Masliah, E.5
Mucke, L.6
-
227
-
-
0027482675
-
Short-term synaptic plasticity is altered in mice lacking synapsin I
-
ROSAHL, T. W., M. GEPPERT, D. SPILLANE, J. HERZ, R. E. HAMMER, R. C. MALENKA, AND T. C. SUDHOF. Short-term synaptic plasticity is altered in mice lacking synapsin I. Cell 75: 661-670, 1993.
-
(1993)
Cell
, vol.75
, pp. 661-670
-
-
Rosahl, T.W.1
Geppert, M.2
Spillane, D.3
Herz, J.4
Hammer, R.E.5
Malenka, R.C.6
Sudhof, T.C.7
-
228
-
-
0029024135
-
Essential functions of synapsins I and II in synaptic vesicle regulation
-
ROSAHL, T. W., D. SPILLANE, M. MISSLER, J. HERZ, D. K. SELIG, J. R. WOLFF, R. E. HAMMER, R. C. MALENKA, AND T. C. SUDHOF. Essential functions of synapsins I and II in synaptic vesicle regulation. Nature 375: 488-493, 1995.
-
(1995)
Nature
, vol.375
, pp. 488-493
-
-
Rosahl, T.W.1
Spillane, D.2
Missler, M.3
Herz, J.4
Selig, D.K.5
Wolff, J.R.6
Hammer, R.E.7
Malenka, R.C.8
Sudhof, T.C.9
-
229
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
ROSEN, D., T. SIDDIQUE, D. PATTERSON, D. FIGLEWICZ, P. SAPP, A. HENTATI, D. DONALDSON, J. GOTO, J. O'REGAN, H. DENG, AND R. BROWN. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362: 59-62, 1993.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.9
Deng, H.10
Brown, R.11
-
230
-
-
0030476713
-
Mice expressing activated CaMKII lack low frequency LTP and do not form stable place cells in the CA1 region of the hippocampus
-
ROTENBERG, A., M. MAYFORD, R. D. HAWKINS, E. R. KANDEL, AND R. U. MULLER. Mice expressing activated CaMKII lack low frequency LTP and do not form stable place cells in the CA1 region of the hippocampus. Cell 87: 1351-1361, 1996.
-
(1996)
Cell
, vol.87
, pp. 1351-1361
-
-
Rotenberg, A.1
Mayford, M.2
Hawkins, R.D.3
Kandel, E.R.4
Muller, R.U.5
-
231
-
-
0029441620
-
Excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis
-
ROTHSTEIN, J. Excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis. Adv. Neurol 68: 7-20, 1995.
-
(1995)
Adv. Neurol
, vol.68
, pp. 7-20
-
-
Rothstein, J.1
-
232
-
-
13344286293
-
Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
-
ROTHSTEIN, J., M. DYKES-HOBERG, C. PARDO, L. BRISTOL, L. JIN, R. KUNCL, Y. KANAI, M. HEDIGER, Y. WANG, J. SCHIELKE, AND D. WELTY. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 16: 674-686, 1996.
-
(1996)
Neuron
, vol.16
, pp. 674-686
-
-
Rothstein, J.1
Dykes-Hoberg, M.2
Pardo, C.3
Bristol, L.4
Jin, L.5
Kuncl, R.6
Kanai, Y.7
Hediger, M.8
Wang, Y.9
Schielke, J.10
Welty, D.11
-
233
-
-
0027274623
-
Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity
-
ROTHSTEIN, J., L. LINE, M. DYKES-HOBERG, AND R. KUNCL. Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity. Proc. Natl. Acad. Sci. USA 90: 6591-6595, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6591-6595
-
-
Rothstein, J.1
Line, L.2
Dykes-Hoberg, M.3
Kuncl, R.4
-
234
-
-
0026597010
-
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
-
ROTHSTEIN, J., L. MARTIN, AND R. KUNCL. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N. Engl. J. Med. 336: 1464-1468, 1992.
-
(1992)
N. Engl. J. Med.
, vol.336
, pp. 1464-1468
-
-
Rothstein, J.1
Martin, L.2
Kuncl, R.3
-
235
-
-
0029030610
-
Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
-
ROTHSTEIN, J., M. VAN KAMMEN, A. LEVEY, L. MARTIN, AND R. KUNCL. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann. Neurol. 38: 73-84, 1995.
-
(1995)
Ann. Neurol.
, vol.38
, pp. 73-84
-
-
Rothstein, J.1
Van Kammen, M.2
Levey, A.3
Martin, L.4
Kuncl, R.5
-
236
-
-
0030955365
-
4 receptors are supersensitive to ethanol, cocaine, and methamphetamine
-
4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell 90: 991-1001, 1997.
-
(1997)
Cell
, vol.90
, pp. 991-1001
-
-
Rubinstein, M.1
Phillips, T.J.2
Bunzow, J.R.3
Falzone, T.L.4
Dziewczapolski, G.5
Zhang, G.6
Fang, Y.7
Larson, J.L.8
Mcdougall, J.A.9
Chester, J.A.10
Saez, C.11
Pugsley, T.A.12
Gershanik, O.13
Low, M.J.14
Grandy, D.K.15
-
237
-
-
0030774535
-
The genetics of Alzheimer's disease
-
RUBINSZTEIN, D. C. The genetics of Alzheimer's disease. Prog. Neurobiol. 52: 447-454, 1997.
-
(1997)
Prog. Neurobiol.
, vol.52
, pp. 447-454
-
-
Rubinsztein, D.C.1
-
238
-
-
0030681310
-
Inducible gene expression in mammalian cells and transgenic mice
-
SAEZ, E., D. NO, A. WEST, AND R. EVANS. Inducible gene expression in mammalian cells and transgenic mice. Curr. Opin. Biotechnol. 8: 608-616, 1997.
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 608-616
-
-
Saez, E.1
No, D.2
West, A.3
Evans, R.4
-
239
-
-
13344282734
-
Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PRP gene
-
SAKAGUCHI, S., S. KATAMINE, N. NISHIDA, R. MORIUCHI, K. SHIGEMATSU, T. SUGIMOTO, A. NAKATANI, Y. KATAOKA, T. HOUTANI, S. SHIRABE, H. OKADA, S. HASEGAWA, T. MIYAMOTO, AND T. NODA. Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PRP gene. Nature 380: 528-531, 1996.
-
(1996)
Nature
, vol.380
, pp. 528-531
-
-
Sakaguchi, S.1
Katamine, S.2
Nishida, N.3
Moriuchi, R.4
Shigematsu, K.5
Sugimoto, T.6
Nakatani, A.7
Kataoka, Y.8
Houtani, T.9
Shirabe, S.10
Okada, H.11
Hasegawa, S.12
Miyamoto, T.13
Noda, T.14
-
240
-
-
0028813106
-
Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit
-
SAKIMURA, K., T. KUTSUWADA, I. ITO, T. MANABE, C. TAKAYAMA, E. KUSHIYA, T. YAGI, S. AIZAWA, Y. INOUE, H. SUGIYAMA, AND M. MISHINA. Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit. Nature 373: 151-155, 1995.
-
(1995)
Nature
, vol.373
, pp. 151-155
-
-
Sakimura, K.1
Kutsuwada, T.2
Ito, I.3
Manabe, T.4
Takayama, C.5
Kushiya, E.6
Yagi, T.7
Aizawa, S.8
Inoue, Y.9
Sugiyama, H.10
Mishina, M.11
-
241
-
-
0031015266
-
Genetic alteration of alpha 2C-adrenoceptor expression in mice: Influence on locomotor, hypothermic, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha 2-adrenoceptor agonist
-
SALLINEN, J., R. E. LINK, A. HAAPALINNA, T. VIITAMAA, M. KULATUNGA, B. SJOHOLM, E. MACDONALD, M. PELTO-HUIKKO, T. LEINO, G. S. BARSH, B. K. KOBILKA, AND M. SCHEININ. Genetic alteration of alpha 2C-adrenoceptor expression in mice: influence on locomotor, hypothermic, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha 2-adrenoceptor agonist. Mol. Pharmacol. 51: 36-46, 1997.
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 36-46
-
-
Sallinen, J.1
Link, R.E.2
Haapalinna, A.3
Viitamaa, T.4
Kulatunga, M.5
Sjoholm, B.6
Macdonald, E.7
Pelto-Huikko, M.8
Leino, T.9
Barsh, G.S.10
Kobilka, B.K.11
Scheinin, M.12
-
242
-
-
0024041732
-
Site-specific DNA recombination in mammalian cells by the Cre-recombinase of bacteriophage P1
-
SAUER, B., AND N. HENDERSON. Site-specific DNA recombination in mammalian cells by the Cre-recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. USA 85: 5166-5170, 1988.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5166-5170
-
-
Sauer, B.1
Henderson, N.2
-
243
-
-
0024509412
-
Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome
-
SAUER, B., AND N. HENDERSON. Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome. Nucleic Adds Res. 17: 147-161, 1989.
-
(1989)
Nucleic Adds Res.
, vol.17
, pp. 147-161
-
-
Sauer, B.1
Henderson, N.2
-
244
-
-
0025360095
-
Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase
-
SAUER, B., AND N. HENDERSON. Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase. New Biol. 2: 441-449, 1990.
-
(1990)
New Biol.
, vol.2
, pp. 441-449
-
-
Sauer, B.1
Henderson, N.2
-
245
-
-
0021993385
-
Dissociation between components of spatial memory in rats after recovery from the effects of retrohippocampal lesions
-
SCHENK, F., AND R. G. MORRIS. Dissociation between components of spatial memory in rats after recovery from the effects of retrohippocampal lesions. Exp. Brain Res. 58: 11-28, 1985.
-
(1985)
Exp. Brain Res.
, vol.58
, pp. 11-28
-
-
Schenk, F.1
Morris, R.G.2
-
246
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
SCHEUNER, D., C. ECKMAN, M. JENSEN, X. SONG, M. CITRON, N. SUZUKI, T. BIRD, J. HARDY, M. HUTTON, W. KUKULL, E. LARSON E. LEVT-LAHAD, M. VIITANEN, E. PESKIND, P. POORKAJ, G. SCHELLENBERG, R. TANZI, W. WASCO, L. LANNFELT, D. SELKOE, AND S. YOUNKIN. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nature Med. 2: 864-870, 1996.
-
(1996)
Nature Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levt-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
247
-
-
2642625666
-
Temporally and spatially regulated somatic mutagenesis in mice
-
SCHWENK, F., R. KUHN, P.-O. ANGRAND, K. RAJEWSKY, AND A. F. STEWART. Temporally and spatially regulated somatic mutagenesis in mice. Nucleic Acids Res. 26: 1427-1432, 1998.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 1427-1432
-
-
Schwenk, F.1
Kuhn, R.2
Angrand, P.-O.3
Rajewsky, K.4
Stewart, A.F.5
-
248
-
-
0028170818
-
Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease
-
SELKOE, D. Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease. Annu. Rev. Cell Biol. 10: 373-403, 1994.
-
(1994)
Annu. Rev. Cell Biol.
, vol.10
, pp. 373-403
-
-
Selkoe, D.1
-
249
-
-
0029784838
-
Amyloid beta-protein and the genetics of Alzheimer's disease
-
SELKOE, D. J. Amyloid beta-protein and the genetics of Alzheimer's disease. J. Biol. Chem. 271: 18295-18298, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 18295-18298
-
-
Selkoe, D.J.1
-
250
-
-
0028048374
-
Excitotoxicity and motor neurone disease: A review of the evidence
-
SHAW, P. Excitotoxicity and motor neurone disease: a review of the evidence. J. Neural. Sci. 124: 6-13, 1994.
-
(1994)
J. Neural. Sci.
, vol.124
, pp. 6-13
-
-
Shaw, P.1
-
251
-
-
0030927075
-
Glutamate, excitotoxicity and amyotrophic lateral sclerosis
-
SHAW, P., AND P. INCE. Glutamate, excitotoxicity and amyotrophic lateral sclerosis. J. Neurol. 244, Suppl: S3-S14, 1997.
-
(1997)
J. Neurol.
, vol.244
, Issue.SUPPL.
-
-
Shaw, P.1
Ince, P.2
-
253
-
-
0029021083
-
A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice
-
SHOCKETT, P., M. DIFILIPPANTONIO, N. HELLMAN, AND D. SCHATZ. A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice. Proc. Natl. Acad. Sci. USA 92: 6522-6526, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 6522-6526
-
-
Shockett, P.1
Difilippantonio, M.2
Hellman, N.3
Schatz, D.4
-
255
-
-
0026742451
-
Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice
-
SILVA, A. J., R. PAYLOR, J. M. WEHNER, AND S. TONEGAWA. Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice. Science 257: 206-211, 1992.
-
(1992)
Science
, vol.257
, pp. 206-211
-
-
Silva, A.J.1
Paylor, R.2
Wehner, J.M.3
Tonegawa, S.4
-
256
-
-
0030777698
-
Mutant mice and neuroscience: Recommendations concerning genetic background
-
SILVA, A. J., E. M. SIMPSON, J. S. TAKAHASHI, H.-P. LIPP, S. NAKANISHI, J. M. WEHNER, K. P. GIESE, T. TULLY, T. ABEL, P. F. CHAPMAN, S. GRANT, S. ITOHARA, R. LATHE, M. MAYFORD, J. O. MCNAMARA, R. J. MORRIS, M. PICCIOTTO, J. RODER, H.-S. SHIN, P. A. SLESINGER, D. R. STORM, M. P. STRYKER, S. TONEGAWA, Y. WANG, AND D. P. WOLFER. Mutant mice and neuroscience: recommendations concerning genetic background. Neuron 19: 755-759, 1997.
-
(1997)
Neuron
, vol.19
, pp. 755-759
-
-
Silva, A.J.1
Simpson, E.M.2
Takahashi, J.S.3
Lipp, H.-P.4
Nakanishi, S.5
Wehner, J.M.6
Giese, K.P.7
Tully, T.8
Abel, T.9
Chapman, P.F.10
Grant, S.11
Itohara, S.12
Lathe, R.13
Mayford, M.14
Mcnamara, J.O.15
Morris, R.J.16
Picciotto, M.17
Roder, J.18
Shin, H.-S.19
Slesinger, P.A.20
Storm, D.R.21
Stryker, M.P.22
Tonegawa, S.23
Wang, Y.24
Wolfer, D.P.25
more..
-
257
-
-
0026637195
-
Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice
-
SILVA, A. J., C. STEVENS, S. TONEGAWA, AND Y. WANG. Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice. Science 257: 201-206, 1992.
-
(1992)
Science
, vol.257
, pp. 201-206
-
-
Silva, A.J.1
Stevens, C.2
Tonegawa, S.3
Wang, Y.4
-
260
-
-
0030725268
-
+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice
-
+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice. Proc. Natl. Acad. Sci. USA 94: 12210-12217, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12210-12217
-
-
Slesinger, P.1
Stoffel, M.2
Jan, Y.3
Jan, L.4
-
261
-
-
0026649122
-
An animal model for cystic fibrosis made by gene targeting
-
SNOUWAERT, J. N., K. K. BRIGMAN, A. M. LATOUR, N. N. MALOUF, R. C. BOUCHER, O. SMITHIES, AND B. H. KOLLER. An animal model for cystic fibrosis made by gene targeting. Science 257: 1083-1088, 1992.
-
(1992)
Science
, vol.257
, pp. 1083-1088
-
-
Snouwaert, J.N.1
Brigman, K.K.2
Latour, A.M.3
Malouf, N.N.4
Boucher, R.C.5
Smithies, O.6
Koller, B.H.7
-
262
-
-
0026717588
-
Glutamate receptor channels: Novel properties and new clones
-
SOMMER, B., AND P. SEEBURG. Glutamate receptor channels: novel properties and new clones. Trends Pharmacol. Sci. 13: 291-296, 1992.
-
(1992)
Trends Pharmacol. Sci.
, vol.13
, pp. 291-296
-
-
Sommer, B.1
Seeburg, P.2
-
263
-
-
0031030042
-
Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia
-
SORA, I., N. TAKAHASHI, M. FUNADA, H. UJIKE, R. S. REVAY, D. M. DONOVAN, L. L. MINER, AND G. R. UHL. Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia Proc. Natl. Acad. Sci. USA 94: 1544-1549, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1544-1549
-
-
Sora, I.1
Takahashi, N.2
Funada, M.3
Ujike, H.4
Revay, R.S.5
Donovan, D.M.6
Miner, L.L.7
Uhl, G.R.8
-
264
-
-
0028916393
-
Gene targeting in ES cells
-
SORIANO, P. Gene targeting in ES cells. Annu. Rev. Neurosci. 18: 1-18, 1995.
-
(1995)
Annu. Rev. Neurosci.
, vol.18
, pp. 1-18
-
-
Soriano, P.1
-
265
-
-
0028788822
-
Long-term potentiation in mice lacking synapsins
-
SPILLANE, D. M., T. W. ROSAHL, T. C. SUDHOF, AND R. C. MALENKA. Long-term potentiation in mice lacking synapsins. Neuropharmacology 34: 1573-1579, 1995.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1573-1579
-
-
Spillane, D.M.1
Rosahl, T.W.2
Sudhof, T.C.3
Malenka, R.C.4
-
266
-
-
0030222252
-
Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains
-
STEVENS, K. E., R. FREEDMAN, A. C. COLLINS, M. HALL, S. LEONARD, M. J. MARKS, AND G. M. ROSE. Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains. Neuropsychopharmacology 15: 152-162, 1996.
-
(1996)
Neuropsychopharmacology
, vol.15
, pp. 152-162
-
-
Stevens, K.E.1
Freedman, R.2
Collins, A.C.3
Hall, M.4
Leonard, S.5
Marks, M.J.6
Rose, G.M.7
-
267
-
-
0028990256
-
Nicotinic cholinergic normalization of amphetamine-induced loss of auditory gating in freely moving rats
-
STEVENS, K. E., J. MELTZER, AND G. M. ROSE. Nicotinic cholinergic normalization of amphetamine-induced loss of auditory gating in freely moving rats. Psychopharmacology 119: 163-170, 1995.
-
(1995)
Psychopharmacology
, vol.119
, pp. 163-170
-
-
Stevens, K.E.1
Meltzer, J.2
Rose, G.M.3
-
268
-
-
0029655448
-
The involvement of dopamine in the striatum in passive avoidance training in the chick
-
STEWART, M. G., P. KABAI, E. HARRISON, R. J. STEELE, M. KOSSUT, M. GIERDALSKI, AND A. CSILLAG. The involvement of dopamine in the striatum in passive avoidance training in the chick. Neuroscience 70: 7-14, 1996.
-
(1996)
Neuroscience
, vol.70
, pp. 7-14
-
-
Stewart, M.G.1
Kabai, P.2
Harrison, E.3
Steele, R.J.4
Kossut, M.5
Gierdalski, M.6
Csillag, A.7
-
269
-
-
0029859602
-
Rapid construction in yeast of complex targeting vectors for gene manipulation in the mouse
-
STORCK, T., U. KRUTH, R. KOLHEKAR, R. SPRENGEL, AND P. H. SEEBURG. Rapid construction in yeast of complex targeting vectors for gene manipulation in the mouse. Nucleic Acids Res. 24: 4594-4596, 1996.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 4594-4596
-
-
Storck, T.1
Kruth, U.2
Kolhekar, R.3
Sprengel, R.4
Seeburg, P.H.5
-
270
-
-
0023109592
-
Amyloid β-protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer's locus
-
TANZI, R., J. GUSELLA, P. WATKINS, G. BRUNS, P. ST. GEORGEHYSLOP, M. VAN KEUREN, D. PATTERSON, S. PAGAN, D. KURNIT, AND R. NEVE. Amyloid β-protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer's locus. Science 235: 880-884, 1987.
-
(1987)
Science
, vol.235
, pp. 880-884
-
-
Tanzi, R.1
Gusella, J.2
Watkins, P.3
Bruns, G.4
St. Georgehyslop, P.5
Van Keuren, M.6
Patterson, D.7
Pagan, S.8
Kurnit, D.9
Neve, R.10
-
271
-
-
0026771287
-
Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs
-
TE RIELE, H., E. ROBANUS MAANDAG, AND A. BERNS. Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc. Natl. Acad. Sci. USA 89: 5128-5132, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5128-5132
-
-
Te Riele, H.1
Robanus Maandag, E.2
Berns, A.3
-
272
-
-
0022968046
-
Targeting of genes to specific sites in the mammalian genome
-
THOMAS, K., AND M. CAPECCHI. Targeting of genes to specific sites in the mammalian genome. Cold Spring Harbor Symp. Quant. Biol.: 1101-1113, 1986.
-
(1986)
Cold Spring Harbor Symp. Quant. Biol.
, pp. 1101-1113
-
-
Thomas, K.1
Capecchi, M.2
-
273
-
-
0026770668
-
High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors
-
THOMAS, K., C. DENG, AND M. CAPECCHI. High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors. Mol. Cell. Biol. 12: 2919-2923, 1992.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2919-2923
-
-
Thomas, K.1
Deng, C.2
Capecchi, M.3
-
274
-
-
0030951587
-
Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice
-
TIAN, M., H. E. BROXMEYER, Y. FAN, Z. LAI, S. ZHANG, S. ARONICA, S. COOPER, R. M. BIGSBY, R. STEINMETZ, S. J. ENGLE, A. MESTEK, J. D. POLLOCK, M. N. LEHMAN, H. T. JANSEN, M. YING, P. J. STAMBROOK, J. A. TISCHFIELD, AND L. YU. Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice. J. Exp. Med. 185: 1517-1522, 1997.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1517-1522
-
-
Tian, M.1
Broxmeyer, H.E.2
Fan, Y.3
Lai, Z.4
Zhang, S.5
Aronica, S.6
Cooper, S.7
Bigsby, R.M.8
Steinmetz, R.9
Engle, S.J.10
Mestek, A.11
Pollock, J.D.12
Lehman, M.N.13
Jansen, H.T.14
Ying, M.15
Stambrook, P.J.16
Tischfield, J.A.17
Yu, L.18
-
275
-
-
15844421385
-
Altered circadian activity rhythms and sleep in mice devoid of prion protein
-
TOBLER, I., S. E. GAUS, T. DEBOER, P. ACHERMANN, M. FISCHER, T. RULICKE, M. MOSER, B. OESCH, P. A. MCBRIDE, AND J. C. MANSON. Altered circadian activity rhythms and sleep in mice devoid of prion protein. Nature 380: 639-642, 1996.
-
(1996)
Nature
, vol.380
, pp. 639-642
-
-
Tobler, I.1
Gaus, S.E.2
Deboer, T.3
Achermann, P.4
Fischer, M.5
Rulicke, T.6
Moser, M.7
Oesch, B.8
Mcbride, P.A.9
Manson, J.C.10
-
276
-
-
0030439806
-
Hippocampal CA1-region-restricted knockout of NMDAR1 gene disrupts synaptic plasticity, place fields, and spatial learning
-
TONEGAWA, S., J. Z. TSIEN, T. J. MCHUGH, P. HUERTA, K. I. BLUM, AND M. A. WILSON. Hippocampal CA1-region-restricted knockout of NMDAR1 gene disrupts synaptic plasticity, place fields, and spatial learning. Cold Spring Harbor Symp. Quant. Biol. 61: 225-238, 1996.
-
(1996)
Cold Spring Harbor Symp. Quant. Biol.
, vol.61
, pp. 225-238
-
-
Tonegawa, S.1
Tsien, J.Z.2
Mchugh, T.J.3
Huerta, P.4
Blum, K.I.5
Wilson, M.A.6
-
277
-
-
0025014631
-
Latency to enter a mirrored chamber: A novel behavioral assay for anxiolytic agents
-
TOUBAS, P., K. ABLA, W. CAO, L. LOGAN, AND T. SEALE. Latency to enter a mirrored chamber: a novel behavioral assay for anxiolytic agents. Pharmacol. Biochem. Behav. 35: 121-126, 1990.
-
(1990)
Pharmacol. Biochem. Behav.
, vol.35
, pp. 121-126
-
-
Toubas, P.1
Abla, K.2
Cao, W.3
Logan, L.4
Seale, T.5
-
278
-
-
0030460425
-
Subregion- and cell type-restricted gene knockout in mouse brain
-
TSIEN, J., D. CHEN, D. GERBER, C. TOM, E. MERCER, D. ANDERSON, M. MAYFORD, E. KANDEL, AND S. TONEGAWA. Subregion- and cell type-restricted gene knockout in mouse brain. Cell 87: 1317-1326, 1996.
-
(1996)
Cell
, vol.87
, pp. 1317-1326
-
-
Tsien, J.1
Chen, D.2
Gerber, D.3
Tom, C.4
Mercer, E.5
Anderson, D.6
Mayford, M.7
Kandel, E.8
Tonegawa, S.9
-
279
-
-
0030446363
-
The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
-
TSIEN, J. Z., P. T. HUERTA, AND S. TONEGAWA. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87: 1327-1338, 1996.
-
(1996)
Cell
, vol.87
, pp. 1327-1338
-
-
Tsien, J.Z.1
Huerta, P.T.2
Tonegawa, S.3
-
280
-
-
0029966363
-
Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
-
TU, P.-H., P. RAJU, K. ROBINSON, M. GURNEY, J. TROJANOWSKI, AND V.-Y. LEE. Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc. Natl. Acad. Sci. USA 93: 3155-3160, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3155-3160
-
-
Tu, P.-H.1
Raju, P.2
Robinson, K.3
Gurney, M.4
Trojanowski, J.5
Lee, V.-Y.6
-
281
-
-
0021026485
-
Behavioural and neurochemical studies of the action of atypical antidepressants
-
VALDMAN, A. V., N. A. AVDULOV, V. V. ROZGANETS, AND D. Y. RUSACOV. Behavioural and neurochemical studies of the action of atypical antidepressants. Acta Physiol. Pharmacol. Bulg. 9: 3-10, 1983.
-
(1983)
Acta Physiol. Pharmacol. Bulg.
, vol.9
, pp. 3-10
-
-
Valdman, A.V.1
Avdulov, N.A.2
Rozganets, V.V.3
Rusacov, D.Y.4
-
282
-
-
0030907828
-
Targeted gene disruption: Applications in neurobiology
-
VAN DER NEUT, R. Targeted gene disruption: applications in neurobiology. J. Neurosci. Methods 71: 19-27, 1997.
-
(1997)
J. Neurosci. Methods
, vol.71
, pp. 19-27
-
-
Van Der Neut, R.1
-
283
-
-
0026737822
-
Targeting of the creatine kinase M gene in embryonic stem cells using isogenic and nonisogenic vectors
-
VAN DUERSEN, J., AND B. WIERINGA. Targeting of the creatine kinase M gene in embryonic stem cells using isogenic and nonisogenic vectors. Nucleic Acids Res. 20: 3815-3820, 1992.
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 3815-3820
-
-
Van Duersen, J.1
Wieringa, B.2
-
284
-
-
0026560826
-
Targeted homologous recombination in mammalian cells
-
WALDMAN, A. Targeted homologous recombination in mammalian cells. Crit. Rev. Oncol. Hematol 12: 49-64, 1992.
-
(1992)
Crit. Rev. Oncol. Hematol
, vol.12
, pp. 49-64
-
-
Waldman, A.1
-
285
-
-
8044231311
-
The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum
-
WALTER, J., A. CAPELL, J. GRUNBERG, B. PESOLD, A. SCHINDZIELORZ, R. PRIOR, M. PODLISNY, P. FRASER, P. ST. GEORGEHYSLOP, D. SELKOE, AND C. HAASS. The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum. Modern Med. 2: 673-691, 1996.
-
(1996)
Modern Med.
, vol.2
, pp. 673-691
-
-
Walter, J.1
Capell, A.2
Grunberg, J.3
Pesold, B.4
Schindzielorz, A.5
Prior, R.6
Podlisny, M.7
Fraser, P.8
St. Georgehyslop, P.9
Selkoe, D.10
Haass, C.11
-
286
-
-
0030018512
-
The use of null mutant mice to study complex learning and memory processes
-
WEHNER, J. M., B. J. BOWERS, AND R. PAYLOR. The use of null mutant mice to study complex learning and memory processes. Behav. Genet. 26: 301-312, 1996.
-
(1996)
Behav. Genet.
, vol.26
, pp. 301-312
-
-
Wehner, J.M.1
Bowers, B.J.2
Paylor, R.3
-
287
-
-
0031909974
-
Abnormal heart rate regulation in GIRK4 knockout mice
-
WICKMAN, K., J. NEMEC, S. GENDER, AND D. CLAPHAM. Abnormal heart rate regulation in GIRK4 knockout mice. Neuron 20: 103-114, 1998.
-
(1998)
Neuron
, vol.20
, pp. 103-114
-
-
Wickman, K.1
Nemec, J.2
Gender, S.3
Clapham, D.4
-
288
-
-
0032498272
-
Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin
-
WINDER, D. G., I. M. MANSUY, M. OSMAN, T. M. MOALLEM, AND E. R. KANDEL. Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin. Cell 92: 25-37, 1998.
-
(1998)
Cell
, vol.92
, pp. 25-37
-
-
Winder, D.G.1
Mansuy, I.M.2
Osman, M.3
Moallem, T.M.4
Kandel, E.R.5
-
289
-
-
0029079993
-
Motor neuron disease caused by mutations in superoxide dismutase 1
-
WONG, P., AND D. BORCHELT. Motor neuron disease caused by mutations in superoxide dismutase 1. Curr. Opin. Neurol. 8: 294-301, 1995.
-
(1995)
Curr. Opin. Neurol.
, vol.8
, pp. 294-301
-
-
Wong, P.1
Borchelt, D.2
-
290
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
WONG, P., C. PARDO, D. BORCHELT, M. LEE, N. COPELAND, N. JENKINS, S. SISODIA, D. CLEVELAND, AND D. PRICE. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14: 1105-1116, 1995.
-
(1995)
Neuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.1
Pardo, C.2
Borchelt, D.3
Lee, M.4
Copeland, N.5
Jenkins, N.6
Sisodia, S.7
Cleveland, D.8
Price, D.9
-
291
-
-
0029077755
-
Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-β1
-
WYSS-CORAY, T., L. FENG, E. MASLIAH, M. RUPPE, H. LEE, S. TOGGAS, E. ROCKENSTEIN, AND L. MUCKE. Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-β1. Am. J. Pathol. 147: 53-67, 1995.
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 53-67
-
-
Wyss-Coray, T.1
Feng, L.2
Masliah, E.3
Ruppe, M.4
Lee, H.5
Toggas, S.6
Rockenstein, E.7
Mucke, L.8
-
292
-
-
0028844541
-
Assembly of voltage-gated potassium channels. Conserved hydrophilic motifs determine subfamily-specifc interactions between the alpha-subunits
-
XU, J., W. YU, Y. JAN, L. JAN, AND M. LI. Assembly of voltage-gated potassium channels. Conserved hydrophilic motifs determine subfamily-specifc interactions between the alpha-subunits. J. Biol. Chem. 270: 24761-24768, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24761-24768
-
-
Xu, J.1
Yu, W.2
Jan, Y.3
Jan, L.4
Li, M.5
-
293
-
-
0027945523
-
Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses
-
XU, M., R. MORATALLA, L. H. GOLD, N. HIROI, G. F. KOOB, A. M. GRAYBIEL, AND S. TONEGAWA. Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses. Cell 79: 729-742, 1994.
-
(1994)
Cell
, vol.79
, pp. 729-742
-
-
Xu, M.1
Moratalla, R.2
Gold, L.H.3
Hiroi, N.4
Koob, G.F.5
Graybiel, A.M.6
Tonegawa, S.7
-
294
-
-
0027410516
-
Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
-
XU, Z., L. CORK, J. GRIFFIN, AND D. CLEVELAND. Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell 73: 23-33, 1993.
-
(1993)
Cell
, vol.73
, pp. 23-33
-
-
Xu, Z.1
Cork, L.2
Griffin, J.3
Cleveland, D.4
-
295
-
-
0025672645
-
Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection
-
YAGI, T., Y. IKAWA, K. YOSHIDA, Y. SHIGETANI, N. TAKEDA, I. MABUCHI, T. YAMAMOTO, AND S. AIZAWA. Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection. Proc. Natl. Acad. Sci. USA 87: 9918-9922, 1990.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 9918-9922
-
-
Yagi, T.1
Ikawa, Y.2
Yoshida, K.3
Shigetani, Y.4
Takeda, N.5
Mabuchi, I.6
Yamamoto, T.7
Aizawa, S.8
-
296
-
-
0030842624
-
Homologous recombination based modification in Esherichia coll and germline transmission in transgenic mice of a bacterial artificial chromosome
-
YANG, X., P. MODEL, AND N. HEINTZ. Homologous recombination based modification in Esherichia coll and germline transmission in transgenic mice of a bacterial artificial chromosome. Nature Biotechnol. 15: 859-865, 1997.
-
(1997)
Nature Biotechnol.
, vol.15
, pp. 859-865
-
-
Yang, X.1
Model, P.2
Heintz, N.3
-
297
-
-
0028973628
-
Chronic elevation of S100β protein does not alter APP mRNA expression or promote β-amyloid deposition in the brains of aging transgenic mice
-
YAO, J., C. KITT, AND R. REEVES. Chronic elevation of S100β protein does not alter APP mRNA expression or promote β-amyloid deposition in the brains of aging transgenic mice. Brain Res. 702: 32-36, 1995.
-
(1995)
Brain Res.
, vol.702
, pp. 32-36
-
-
Yao, J.1
Kitt, C.2
Reeves, R.3
-
298
-
-
9344255435
-
Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2
-
YOKOI, M., K. KOBAYASHI, T. MANABE, T. TAKAHASHI, I. SAKAGUCHI, G. KATSUURA, R. SHIGEMOTO, H. OHISHI, S. NOMURA, K. NAKAMURA, K. NAKAO, M. KATSUKI, AND S. NAKANISHI. Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2. Science 273: 645-647, 1996.
-
(1996)
Science
, vol.273
, pp. 645-647
-
-
Yokoi, M.1
Kobayashi, K.2
Manabe, T.3
Takahashi, T.4
Sakaguchi, I.5
Katsuura, G.6
Shigemoto, R.7
Ohishi, H.8
Nomura, S.9
Nakamura, K.10
Nakao, K.11
Katsuki, M.12
Nakanishi, S.13
-
299
-
-
0025953030
-
The modulation of rat hippocampal synaptic conductances by baclofen and γ-aminobutyric acid
-
YOON, K-W., AND S. ROTHMAN. The modulation of rat hippocampal synaptic conductances by baclofen and γ-aminobutyric acid. J. Physiol. (Lond.) 442: 377-390, 1991.
-
(1991)
J. Physiol. (Lond.)
, vol.442
, pp. 377-390
-
-
Yoon, K.-W.1
Rothman, S.2
-
300
-
-
0028988801
-
β-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
-
ZHENG, H., M. JIANG, M. TRUMBAUER, S. SIRINATHSINGHJI, R. HOPKINS, D. SMITH, R. HEAVENS, G. DAWSON, S. BOYCE, M. CONNER, K. STEVENS, H. SLUNT, S. SISODIA, H. CHEN, AND L. VAN DER PLOEG. β-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Cell 81: 525-531, 1995.
-
(1995)
Cell
, vol.81
, pp. 525-531
-
-
Zheng, H.1
Jiang, M.2
Trumbauer, M.3
Sirinathsinghji, S.4
Hopkins, R.5
Smith, D.6
Heavens, R.7
Dawson, G.8
Boyce, S.9
Conner, M.10
Stevens, K.11
Slunt, H.12
Sisodia, S.13
Chen, H.14
Van Der Ploeg, L.15
-
301
-
-
0029588435
-
Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic
-
ZHOU, Q. Y., AND R. D. PALMITER. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell 83: 1197-1209, 1995.
-
(1995)
Cell
, vol.83
, pp. 1197-1209
-
-
Zhou, Q.Y.1
Palmiter, R.D.2
-
302
-
-
0028912476
-
Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development
-
ZHOU, Q. Y., C. J. QUAIFE, AND R. D. PALMITER. Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. Nature 374: 640-643, 1995.
-
(1995)
Nature
, vol.374
, pp. 640-643
-
-
Zhou, Q.Y.1
Quaife, C.J.2
Palmiter, R.D.3
-
303
-
-
0028235845
-
Gene targeting constructs: Effects of vector topology on co-expression efficiency of positive and negative selectable markers
-
ZIMMER, A., A. ZIMMER, AND K. REYNOLDS. Gene targeting constructs: effects of vector topology on co-expression efficiency of positive and negative selectable markers. Biochem. Biophys. Res. Commun. 201: 943-949, 1994.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.201
, pp. 943-949
-
-
Zimmer, A.1
Zimmer, A.2
Reynolds, K.3
-
304
-
-
0028675511
-
Cre-loxP-mediated gene replacement: A mouse strain producing humanized antibodies
-
ZOU, Y. R., W. MULLER, H. GU, AND K. RAJEWSKY. Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies. Curr. Biol. 4: 1099-1103, 1994.
-
(1994)
Curr. Biol.
, vol.4
, pp. 1099-1103
-
-
Zou, Y.R.1
Muller, W.2
Gu, H.3
Rajewsky, K.4
-
305
-
-
0024600340
-
Short-term synaptic plasticity
-
ZUCKER, R. Short-term synaptic plasticity. Annu. Rev. Neurosci. 12: 13-31, 1989.
-
(1989)
Annu. Rev. Neurosci.
, vol.12
, pp. 13-31
-
-
Zucker, R.1
|