Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 7, 1996, Pages 3155-3160

  Tu, Pang Hsien ^a   Raju, Pramod ^a   Robinson, Kathryn A ^a   Gurney, Mark E ^b   Trojanowski, John Q ^a   Lee, Virginia M Y ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

free radicals; motor neuron disease; neurofilaments; spheroids

Indexed keywords

SUPEROXIDE DISMUTASE;

AMINO ACID SUBSTITUTION; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTOSIS; CYTOSKELETON; GENE MUTATION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

AGING; ALANINE; AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CYTOSKELETON; GLYCINE; HUMANS; MACROMOLECULAR SUBSTANCES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; PHOSPHORYLATION; POINT MUTATION; SPINAL CORD; SUPEROXIDE DISMUTASE;

EID: 0029966363     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.7.3155     Document Type: Article

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