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Volumn 12, Issue , 2017, Pages 18-34

Angiogenesis in the atherosclerotic plaque

Author keywords

Angiogenesis; Atherosclerosis; Hypercholesterolemia; Neovascularization; VEGF

Indexed keywords

ALDEHYDE; ANGIOGENESIS INHIBITOR; ANGIOGENIC FACTOR; ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; CHOLESTEROL; EPIDERMAL GROWTH FACTOR RECEPTOR; FATTY ACID DERIVATIVE; FIBROBLAST GROWTH FACTOR 2; HYPOXIA INDUCIBLE FACTOR; METALLOPROTEINASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; VASCULOTROPIN ANTIBODY; VASCULOTROPIN RECEPTOR;

EID: 85012306563     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2017.01.007     Document Type: Review
Times cited : (311)

References (322)
  • 1
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: a perspective for the 1990s
    • [1] Ross, R., The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362:6423 (1993), 801–809.
    • (1993) Nature , vol.362 , Issue.6423 , pp. 801-809
    • Ross, R.1
  • 2
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • [2] Lusis, A.J., Atherosclerosis. Nature 407:6801 (2000), 233–241.
    • (2000) Nature , vol.407 , Issue.6801 , pp. 233-241
    • Lusis, A.J.1
  • 3
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • [3] Libby, P., Inflammation in atherosclerosis. Nature 420:6917 (2002), 868–874.
    • (2002) Nature , vol.420 , Issue.6917 , pp. 868-874
    • Libby, P.1
  • 5
    • 84900865991 scopus 로고    scopus 로고
    • Pathology of human plaque vulnerability: mechanisms and consequences of intraplaque haemorrhages
    • [5] Michel, J.B., Martin-Ventura, J.L., Nicoletti, A., Ho-Tin-Noe, B., Pathology of human plaque vulnerability: mechanisms and consequences of intraplaque haemorrhages. Atherosclerosis 234:2 (2014), 311–319.
    • (2014) Atherosclerosis , vol.234 , Issue.2 , pp. 311-319
    • Michel, J.B.1    Martin-Ventura, J.L.2    Nicoletti, A.3    Ho-Tin-Noe, B.4
  • 6
    • 77649168107 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor therapies and cardiovascular toxicity: what are the important clinical markers to target?
    • [6] Vaklavas, C., Lenihan, D., Kurzrock, R., Tsimberidou, A.M., Anti-vascular endothelial growth factor therapies and cardiovascular toxicity: what are the important clinical markers to target?. Oncologist 15:2 (2010), 130–141.
    • (2010) Oncologist , vol.15 , Issue.2 , pp. 130-141
    • Vaklavas, C.1    Lenihan, D.2    Kurzrock, R.3    Tsimberidou, A.M.4
  • 7
    • 84871277637 scopus 로고    scopus 로고
    • Vasa vasorum and plaque progression, and responses to atorvastatin in a rabbit model of atherosclerosis: contrast-enhanced ultrasound imaging and intravascular ultrasound study
    • [7] Tian, J., Hu, S., Sun, Y., Yu, H., Han, X., Cheng, W., Ban, X., Zhang, S., Yu, B., Jang, I.K., Vasa vasorum and plaque progression, and responses to atorvastatin in a rabbit model of atherosclerosis: contrast-enhanced ultrasound imaging and intravascular ultrasound study. Heart 99:1 (2013), 48–54.
    • (2013) Heart , vol.99 , Issue.1 , pp. 48-54
    • Tian, J.1    Hu, S.2    Sun, Y.3    Yu, H.4    Han, X.5    Cheng, W.6    Ban, X.7    Zhang, S.8    Yu, B.9    Jang, I.K.10
  • 9
    • 0029097154 scopus 로고
    • A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis
    • [9] Stary, H.C., Chandler, A.B., Dinsmore, R.E., Fuster, V., Glagov, S., Insull, W. Jr., Rosenfeld, M.E., Schwartz, C.J., Wagner, W.D., Wissler, R.W., A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis. Am. Heart Assoc. Circ. 92:5 (1995), 1355–1374.
    • (1995) Am. Heart Assoc. Circ. , vol.92 , Issue.5 , pp. 1355-1374
    • Stary, H.C.1    Chandler, A.B.2    Dinsmore, R.E.3    Fuster, V.4    Glagov, S.5    Insull, W.6    Rosenfeld, M.E.7    Schwartz, C.J.8    Wagner, W.D.9    Wissler, R.W.10
  • 12
    • 57749092004 scopus 로고    scopus 로고
    • The pathology of atherosclerosis: plaque development and plaque responses to medical treatment
    • [12] Insull, W. Jr., The pathology of atherosclerosis: plaque development and plaque responses to medical treatment. Am. J. Med 122:1 Suppl (2009), S3–S14.
    • (2009) Am. J. Med , vol.122 , Issue.1 , pp. S3-S14
    • Insull, W.1
  • 14
    • 0001271809 scopus 로고
    • Endarteritis and arteritis
    • [14] Koester, W., Endarteritis and arteritis. Berl. Klin. Woche. 13 (1876), 454–455.
    • (1876) Berl. Klin. Woche. , vol.13 , pp. 454-455
    • Koester, W.1
  • 15
    • 0003770661 scopus 로고
    • The Biology of Arteriosclerosis
    • C. Thomas Pub Springfield, IL
    • [15] Winternitz, M.C., Thomas, R.M., LeCompte, P.M., The Biology of Arteriosclerosis. 1938, C. Thomas Pub, Springfield, IL.
    • (1938)
    • Winternitz, M.C.1    Thomas, R.M.2    LeCompte, P.M.3
  • 16
    • 0000582946 scopus 로고
    • Intimal vascularization and atherosclerosis
    • [16] Geiringer, E., Intimal vascularization and atherosclerosis. J. Pathol. Bacteriol. 63:2 (1951), 201–211.
    • (1951) J. Pathol. Bacteriol. , vol.63 , Issue.2 , pp. 201-211
    • Geiringer, E.1
  • 17
    • 0030833779 scopus 로고    scopus 로고
    • Atherosclerosis and angiogenesis. Its pathophysiological significance in humans as well as in an animal model induced by the gene transfer of vascular endothelial growth factor
    • [17] Sueishi, K., Yonemitsu, Y., Nakagawa, K., Kaneda, Y., Kumamoto, M., Nakashima, Y., Atherosclerosis and angiogenesis. Its pathophysiological significance in humans as well as in an animal model induced by the gene transfer of vascular endothelial growth factor. Ann. NY Acad. Sci. 811 (1997), 322–324.
    • (1997) Ann. NY Acad. Sci. , vol.811 , pp. 322-324
    • Sueishi, K.1    Yonemitsu, Y.2    Nakagawa, K.3    Kaneda, Y.4    Kumamoto, M.5    Nakashima, Y.6
  • 18
    • 34547812589 scopus 로고    scopus 로고
    • The dynamic vasa vasorum
    • [18] Ritman, E.L., Lerman, A., The dynamic vasa vasorum. Cardiovasc. Res. 75:4 (2007), 649–658.
    • (2007) Cardiovasc. Res. , vol.75 , Issue.4 , pp. 649-658
    • Ritman, E.L.1    Lerman, A.2
  • 20
    • 27844478161 scopus 로고    scopus 로고
    • VEGF-A, VEGF-D and VEGF-D(DeltaNDeltaC) induced intimal hyperplasia in carotid arteries
    • [20] Bhardwaj, S., Roy, H., Heikura, T., Yla-Herttuala, S., VEGF-A, VEGF-D and VEGF-D(DeltaNDeltaC) induced intimal hyperplasia in carotid arteries. Eur. J. Clin. Invest. 35:11 (2005), 669–676.
    • (2005) Eur. J. Clin. Invest. , vol.35 , Issue.11 , pp. 669-676
    • Bhardwaj, S.1    Roy, H.2    Heikura, T.3    Yla-Herttuala, S.4
  • 21
    • 0033528660 scopus 로고    scopus 로고
    • Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice
    • [21] Moulton, K.S., Heller, E., Konerding, M.A., Flynn, E., Palinski, W., Folkman, J., Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Circulation 99:13 (1999), 1726–1732.
    • (1999) Circulation , vol.99 , Issue.13 , pp. 1726-1732
    • Moulton, K.S.1    Heller, E.2    Konerding, M.A.3    Flynn, E.4    Palinski, W.5    Folkman, J.6
  • 22
    • 70349652320 scopus 로고    scopus 로고
    • Prevention of vasa vasorum neovascularization attenuates early neointima formation in experimental hypercholesterolemia
    • [22] Gossl, M., Herrmann, J., Tang, H., Versari, D., Galili, O., Mannheim, D., Rajkumar, S.V., Lerman, L.O., Lerman, A., Prevention of vasa vasorum neovascularization attenuates early neointima formation in experimental hypercholesterolemia. Basic Res Cardiol. 104:6 (2009), 695–706.
    • (2009) Basic Res Cardiol. , vol.104 , Issue.6 , pp. 695-706
    • Gossl, M.1    Herrmann, J.2    Tang, H.3    Versari, D.4    Galili, O.5    Mannheim, D.6    Rajkumar, S.V.7    Lerman, L.O.8    Lerman, A.9
  • 24
    • 0035895737 scopus 로고    scopus 로고
    • Molecular mechanisms of blood vessel growth
    • [24] Conway, E.M., Collen, D., Carmeliet, P., Molecular mechanisms of blood vessel growth. Cardiovasc. Res. 49:3 (2001), 507–521.
    • (2001) Cardiovasc. Res. , vol.49 , Issue.3 , pp. 507-521
    • Conway, E.M.1    Collen, D.2    Carmeliet, P.3
  • 25
    • 16344389190 scopus 로고    scopus 로고
    • Angiogenesis: where do we stand now?
    • [25] Simons, M., Angiogenesis: where do we stand now?. Circulation 111:12 (2005), 1556–1566.
    • (2005) Circulation , vol.111 , Issue.12 , pp. 1556-1566
    • Simons, M.1
  • 26
    • 79953045376 scopus 로고    scopus 로고
    • Augmented angiogenesis in adventitia promotes growth of atherosclerotic plaque in apolipoprotein E-deficient mice
    • [26] Tanaka, K., Nagata, D., Hirata, Y., Tabata, Y., Nagai, R., Sata, M., Augmented angiogenesis in adventitia promotes growth of atherosclerotic plaque in apolipoprotein E-deficient mice. Atherosclerosis 215:2 (2011), 366–373.
    • (2011) Atherosclerosis , vol.215 , Issue.2 , pp. 366-373
    • Tanaka, K.1    Nagata, D.2    Hirata, Y.3    Tabata, Y.4    Nagai, R.5    Sata, M.6
  • 27
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • [27] Carmeliet, P., Angiogenesis in health and disease. Nat. Med 9:6 (2003), 653–660.
    • (2003) Nat. Med , vol.9 , Issue.6 , pp. 653-660
    • Carmeliet, P.1
  • 28
    • 66749187756 scopus 로고    scopus 로고
    • Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis
    • [28] Sluimer, J.C., Daemen, M.J., Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis. J. Pathol. 218:1 (2009), 7–29.
    • (2009) J. Pathol. , vol.218 , Issue.1 , pp. 7-29
    • Sluimer, J.C.1    Daemen, M.J.2
  • 29
    • 84883767696 scopus 로고    scopus 로고
    • Hypoxia in atherosclerosis and inflammation
    • [29] Marsch, E., Sluimer, J.C., Daemen, M.J., Hypoxia in atherosclerosis and inflammation. Curr. Opin. Lipido. 24:5 (2013), 393–400.
    • (2013) Curr. Opin. Lipido. , vol.24 , Issue.5 , pp. 393-400
    • Marsch, E.1    Sluimer, J.C.2    Daemen, M.J.3
  • 30
    • 84860481730 scopus 로고    scopus 로고
    • Plaque neovascularization: defense mechanisms, betrayal, or a war in progress
    • [30] Moreno, P.R., Purushothaman, M., Purushothaman, K.R., Plaque neovascularization: defense mechanisms, betrayal, or a war in progress. Ann. NY Acad. Sci. 1254 (2012), 7–17.
    • (2012) Ann. NY Acad. Sci. , vol.1254 , pp. 7-17
    • Moreno, P.R.1    Purushothaman, M.2    Purushothaman, K.R.3
  • 31
    • 80052933197 scopus 로고    scopus 로고
    • Basic and therapeutic aspects of angiogenesis
    • [31] Potente, M., Gerhardt, H., Carmeliet, P., Basic and therapeutic aspects of angiogenesis. Cell 146:6 (2011), 873–887.
    • (2011) Cell , vol.146 , Issue.6 , pp. 873-887
    • Potente, M.1    Gerhardt, H.2    Carmeliet, P.3
  • 32
    • 54449086418 scopus 로고    scopus 로고
    • Branching morphogenesis
    • [32] Horowitz, A., Simons, M., Branching morphogenesis. Circ. Res. 103:8 (2008), 784–795.
    • (2008) Circ. Res. , vol.103 , Issue.8 , pp. 784-795
    • Horowitz, A.1    Simons, M.2
  • 33
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angiogenesis
    • [33] Carmeliet, P., Jain, R.K., Molecular mechanisms and clinical applications of angiogenesis. Nature 473:7347 (2011), 298–307.
    • (2011) Nature , vol.473 , Issue.7347 , pp. 298-307
    • Carmeliet, P.1    Jain, R.K.2
  • 35
    • 42349114587 scopus 로고    scopus 로고
    • Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead
    • [35] van Hinsbergh, V.W., Koolwijk, P., Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead. Cardiovasc. Res. 78:2 (2008), 203–212.
    • (2008) Cardiovasc. Res. , vol.78 , Issue.2 , pp. 203-212
    • van Hinsbergh, V.W.1    Koolwijk, P.2
  • 36
    • 84874491536 scopus 로고    scopus 로고
    • VEGF and Notch in tip and stalk cell selection
    • [36] Blanco, R., Gerhardt, H., VEGF and Notch in tip and stalk cell selection. Cold Spring Harb. Perspect. Med., 3(1), 2013, a006569.
    • (2013) Cold Spring Harb. Perspect. Med. , vol.3 , Issue.1 , pp. a006569
    • Blanco, R.1    Gerhardt, H.2
  • 37
    • 33847607880 scopus 로고    scopus 로고
    • The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching
    • [37] Suchting, S., Freitas, C., le Noble, F., Benedito, R., Breant, C., Duarte, A., Eichmann, A., The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching. Proc. Natl. Acad. Sci. USA 104:9 (2007), 3225–3230.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , Issue.9 , pp. 3225-3230
    • Suchting, S.1    Freitas, C.2    le Noble, F.3    Benedito, R.4    Breant, C.5    Duarte, A.6    Eichmann, A.7
  • 38
    • 68549085490 scopus 로고    scopus 로고
    • Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way
    • [38] Carmeliet, P., De Smet, F., Loges, S., Mazzone, M., Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way. Nat. Rev. Clin. Oncol. 6:6 (2009), 315–326.
    • (2009) Nat. Rev. Clin. Oncol. , vol.6 , Issue.6 , pp. 315-326
    • Carmeliet, P.1    De Smet, F.2    Loges, S.3    Mazzone, M.4
  • 40
    • 18744362545 scopus 로고    scopus 로고
    • Endothelial progenitor cells functional characterization
    • [40] Urbich, C., Dimmeler, S., Endothelial progenitor cells functional characterization. Trends Cardiovasc. Med. 14:8 (2004), 318–322.
    • (2004) Trends Cardiovasc. Med. , vol.14 , Issue.8 , pp. 318-322
    • Urbich, C.1    Dimmeler, S.2
  • 41
    • 84864541822 scopus 로고    scopus 로고
    • Initiation of angiogenesis in atherosclerosis: smooth muscle cells as mediators of the angiogenic response to atheroma formation
    • [41] Ho-Tin-Noe, B., Michel, J.B., Initiation of angiogenesis in atherosclerosis: smooth muscle cells as mediators of the angiogenic response to atheroma formation. Trends Cardiovasc. Med. 21:7 (2011), 183–187.
    • (2011) Trends Cardiovasc. Med. , vol.21 , Issue.7 , pp. 183-187
    • Ho-Tin-Noe, B.1    Michel, J.B.2
  • 42
    • 84878860572 scopus 로고    scopus 로고
    • Biological mechanisms of microvessel formation in advanced atherosclerosis: the big five
    • [42] Cheng, C., Chrifi, I., Pasterkamp, G., Duckers, H.J., Biological mechanisms of microvessel formation in advanced atherosclerosis: the big five. Trends Cardiovasc. Med. 23:5 (2013), 153–164.
    • (2013) Trends Cardiovasc. Med. , vol.23 , Issue.5 , pp. 153-164
    • Cheng, C.1    Chrifi, I.2    Pasterkamp, G.3    Duckers, H.J.4
  • 43
    • 84935082524 scopus 로고    scopus 로고
    • Endothelial cell metabolism in normal and diseased vasculature
    • [43] Eelen, G., de Zeeuw, P., Simons, M., Carmeliet, P., Endothelial cell metabolism in normal and diseased vasculature. Circ. Res. 116:7 (2015), 1231–1244.
    • (2015) Circ. Res. , vol.116 , Issue.7 , pp. 1231-1244
    • Eelen, G.1    de Zeeuw, P.2    Simons, M.3    Carmeliet, P.4
  • 44
    • 0038037735 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia: role of the HIF system
    • [44] Pugh, C.W., Ratcliffe, P.J., Regulation of angiogenesis by hypoxia: role of the HIF system. Nat. Med. 9:6 (2003), 677–684.
    • (2003) Nat. Med. , vol.9 , Issue.6 , pp. 677-684
    • Pugh, C.W.1    Ratcliffe, P.J.2
  • 45
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • [45] Semenza, G.L., Wang, G.L., A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol. Cell Biol. 12:12 (1992), 5447–5454.
    • (1992) Mol. Cell Biol. , vol.12 , Issue.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 46
    • 0032493368 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway
    • [46] Huang, L.E., Gu, J., Schau, M., Bunn, H.F., Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc. Natl. Acad. Sci. USA 95:14 (1998), 7987–7992.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.14 , pp. 7987-7992
    • Huang, L.E.1    Gu, J.2    Schau, M.3    Bunn, H.F.4
  • 47
    • 0036320934 scopus 로고    scopus 로고
    • Cellular adaptation to hypoxia: o2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression
    • [47] Wenger, R.H., Cellular adaptation to hypoxia: o2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression. FASEB J. 16:10 (2002), 1151–1162.
    • (2002) FASEB J. , vol.16 , Issue.10 , pp. 1151-1162
    • Wenger, R.H.1
  • 48
    • 8344237449 scopus 로고    scopus 로고
    • Hydroxylation of HIF-1: oxygen sensing at the molecular level
    • [48] Semenza, G.L., Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiol. (Bethesda) 19 (2004), 176–182.
    • (2004) Physiol. (Bethesda) , vol.19 , pp. 176-182
    • Semenza, G.L.1
  • 49
    • 33646175288 scopus 로고    scopus 로고
    • The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling
    • [49] Berra, E., Ginouves, A., Pouyssegur, J., The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling. EMBO Rep. 7:1 (2006), 41–45.
    • (2006) EMBO Rep. , vol.7 , Issue.1 , pp. 41-45
    • Berra, E.1    Ginouves, A.2    Pouyssegur, J.3
  • 50
    • 45349097483 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor-1alpha by NF-kappaB
    • [50] van Uden, P., Kenneth, N.S., Rocha, S., Regulation of hypoxia-inducible factor-1alpha by NF-kappaB. Biochem. J. 412:3 (2008), 477–484.
    • (2008) Biochem. J. , vol.412 , Issue.3 , pp. 477-484
    • van Uden, P.1    Kenneth, N.S.2    Rocha, S.3
  • 51
    • 31444444162 scopus 로고    scopus 로고
    • Integration of oxygen signaling at the consensus HRE
    • [51] Wenger, R.H., Stiehl, D.P., Camenisch, G., Integration of oxygen signaling at the consensus HRE. Sci. STKE, 2005(306), 2005, re12.
    • (2005) Sci. STKE , vol.2005 , Issue.306 , pp. re12
    • Wenger, R.H.1    Stiehl, D.P.2    Camenisch, G.3
  • 52
    • 33745138232 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia-inducible factor 1
    • [52] Hirota, K., Semenza, G.L., Regulation of angiogenesis by hypoxia-inducible factor 1. Crit. Rev. Oncol. Hematol. 59:1 (2006), 15–26.
    • (2006) Crit. Rev. Oncol. Hematol. , vol.59 , Issue.1 , pp. 15-26
    • Hirota, K.1    Semenza, G.L.2
  • 53
    • 39749111891 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factors during inflammation
    • [53] Frede, S., Berchner-Pfannschmidt, U., Fandrey, J., Regulation of hypoxia-inducible factors during inflammation. Methods Enzym. 435 (2007), 405–419.
    • (2007) Methods Enzym. , vol.435 , pp. 405-419
    • Frede, S.1    Berchner-Pfannschmidt, U.2    Fandrey, J.3
  • 58
    • 0014304893 scopus 로고
    • Tumor angiogenesis: transfilter diffusion studies in the hamster by the transparent chamber technique
    • [58] Greenblatt, M., Shubi, P., Tumor angiogenesis: transfilter diffusion studies in the hamster by the transparent chamber technique. J. Natl. Cancer Inst. 41:1 (1968), 111–124.
    • (1968) J. Natl. Cancer Inst. , vol.41 , Issue.1 , pp. 111-124
    • Greenblatt, M.1    Shubi, P.2
  • 59
    • 0014365361 scopus 로고
    • Choriocarcinoma. Transfilter stimulation of vasoproliferation in the hamster cheek pouch. Studied by light and electron microscopy
    • [59] Ehrmann, R.L., Knoth, M., Choriocarcinoma. Transfilter stimulation of vasoproliferation in the hamster cheek pouch. Studied by light and electron microscopy. J. Natl. Cancer Inst. 41:6 (1968), 1329–1341.
    • (1968) J. Natl. Cancer Inst. , vol.41 , Issue.6 , pp. 1329-1341
    • Ehrmann, R.L.1    Knoth, M.2
  • 60
    • 0015008620 scopus 로고
    • Isolation of a tumor factor responsible for angiogenesis
    • [60] Folkman, J., Merler, E., Abernathy, C., Williams, G., Isolation of a tumor factor responsible for angiogenesis. J. Exp. Med. 133:2 (1971), 275–288.
    • (1971) J. Exp. Med. , vol.133 , Issue.2 , pp. 275-288
    • Folkman, J.1    Merler, E.2    Abernathy, C.3    Williams, G.4
  • 61
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • [61] Senger, D.R., Galli, S.J., Dvorak, A.M., Perruzzi, C.A., Harvey, V.S., Dvorak, H.F., Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219:4587 (1983), 983–985.
    • (1983) Science , vol.219 , Issue.4587 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 62
    • 0024801035 scopus 로고
    • Vascular permeability factor, an endothelial cell mitogen related to PDGF
    • [62] Keck, P.J., Hauser, S.D., Krivi, G., Sanzo, K., Warren, T., Feder, J., Connolly, D.T., Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 246:4935 (1989), 1309–1312.
    • (1989) Science , vol.246 , Issue.4935 , pp. 1309-1312
    • Keck, P.J.1    Hauser, S.D.2    Krivi, G.3    Sanzo, K.4    Warren, T.5    Feder, J.6    Connolly, D.T.7
  • 63
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • [63] Leung, D.W., Cachianes, G., Kuang, W.J., Goeddel, D.V., Ferrara, N., Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246:4935 (1989), 1306–1309.
    • (1989) Science , vol.246 , Issue.4935 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 64
    • 0024816246 scopus 로고
    • Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells
    • [64] Plouet, J., Schilling, J., Gospodarowicz, D., Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells. EMBO J. 8:12 (1989), 3801–3806.
    • (1989) EMBO J. , vol.8 , Issue.12 , pp. 3801-3806
    • Plouet, J.1    Schilling, J.2    Gospodarowicz, D.3
  • 65
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: basic science and clinical progress
    • [65] Ferrara, N., Vascular endothelial growth factor: basic science and clinical progress. Endocr. Rev. 25:4 (2004), 581–611.
    • (2004) Endocr. Rev. , vol.25 , Issue.4 , pp. 581-611
    • Ferrara, N.1
  • 66
    • 14844357211 scopus 로고    scopus 로고
    • The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease
    • [66] Holmes, D.I., Zachary, I., The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease. Genome Biol., 6(2), 2005, 209.
    • (2005) Genome Biol. , vol.6 , Issue.2 , pp. 209
    • Holmes, D.I.1    Zachary, I.2
  • 67
    • 84949096400 scopus 로고    scopus 로고
    • Vascular endothelial growth factors: a comparison between invertebrates and vertebrates
    • [67] Kipryushina, Y.O., Yakovlev, K.V., Odintsova, N.A., Vascular endothelial growth factors: a comparison between invertebrates and vertebrates. Cytokine Growth Factor Rev. 26:6 (2015), 687–695.
    • (2015) Cytokine Growth Factor Rev. , vol.26 , Issue.6 , pp. 687-695
    • Kipryushina, Y.O.1    Yakovlev, K.V.2    Odintsova, N.A.3
  • 68
    • 0035010433 scopus 로고    scopus 로고
    • Evolution and classification of cystine knot-containing hormones and related extracellular signaling molecules
    • [68] Vitt, U.A., Hsu, S.Y., Hsueh, A.J., Evolution and classification of cystine knot-containing hormones and related extracellular signaling molecules. Mol. Endocrinol. 15:5 (2001), 681–694.
    • (2001) Mol. Endocrinol. , vol.15 , Issue.5 , pp. 681-694
    • Vitt, U.A.1    Hsu, S.Y.2    Hsueh, A.J.3
  • 69
    • 0025999033 scopus 로고
    • The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
    • [69] Tischer, E., Mitchell, R., Hartman, T., Silva, M., Gospodarowicz, D., Fiddes, J.C., Abraham, J.A., The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J. Biol. Chem. 266:18 (1991), 11947–11954.
    • (1991) J. Biol. Chem. , vol.266 , Issue.18 , pp. 11947-11954
    • Tischer, E.1    Mitchell, R.2    Hartman, T.3    Silva, M.4    Gospodarowicz, D.5    Fiddes, J.C.6    Abraham, J.A.7
  • 70
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • [70] Ferrara, N., Gerber, H.P., LeCouter, J., The biology of VEGF and its receptors. Nat. Med. 9:6 (2003), 669–676.
    • (2003) Nat. Med. , vol.9 , Issue.6 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 71
    • 84884971183 scopus 로고    scopus 로고
    • VEGF-A mRNA processing, stability and translation: a paradigm for intricate regulation of gene expression at the post-transcriptional level
    • [71] Arcondeguy, T., Lacazette, E., Millevoi, S., Prats, H., Touriol, C., VEGF-A mRNA processing, stability and translation: a paradigm for intricate regulation of gene expression at the post-transcriptional level. Nucleic Acids Res. 41:17 (2013), 7997–8010.
    • (2013) Nucleic Acids Res. , vol.41 , Issue.17 , pp. 7997-8010
    • Arcondeguy, T.1    Lacazette, E.2    Millevoi, S.3    Prats, H.4    Touriol, C.5
  • 72
    • 25144511910 scopus 로고    scopus 로고
    • The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
    • [72] Takahashi, H., Shibuya, M., The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions. Clin. Sci. (Lond.) 109:3 (2005), 227–241.
    • (2005) Clin. Sci. (Lond.) , vol.109 , Issue.3 , pp. 227-241
    • Takahashi, H.1    Shibuya, M.2
  • 73
    • 54549123309 scopus 로고    scopus 로고
    • VEGF-A splicing: the key to anti-angiogenic therapeutics?
    • [73] Harper, S.J., Bates, D.O., VEGF-A splicing: the key to anti-angiogenic therapeutics?. Nat. Rev. Cancer 8:11 (2008), 880–887.
    • (2008) Nat. Rev. Cancer , vol.8 , Issue.11 , pp. 880-887
    • Harper, S.J.1    Bates, D.O.2
  • 74
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • [74] Shweiki, D., Itin, A., Soffer, D., Keshet, E., Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359:6398 (1992), 843–845.
    • (1992) Nature , vol.359 , Issue.6398 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 75
    • 12344287138 scopus 로고    scopus 로고
    • Transcriptional regulation of the Vascular Endothelial Growth Factor gene-a concert of activating factors
    • [75] Pages, G., Pouyssegur, J., Transcriptional regulation of the Vascular Endothelial Growth Factor gene-a concert of activating factors. Cardiovasc. Res. 65:3 (2005), 564–573.
    • (2005) Cardiovasc. Res. , vol.65 , Issue.3 , pp. 564-573
    • Pages, G.1    Pouyssegur, J.2
  • 78
    • 67649695506 scopus 로고    scopus 로고
    • Atherosclerotic plaque development and instability: a dual role for VEGF
    • [78] Holm, P.W., Slart, R.H., Zeebregts, C.J., Hillebrands, J.L., Tio, R.A., Atherosclerotic plaque development and instability: a dual role for VEGF. Ann. Med. 41:4 (2009), 257–264.
    • (2009) Ann. Med. , vol.41 , Issue.4 , pp. 257-264
    • Holm, P.W.1    Slart, R.H.2    Zeebregts, C.J.3    Hillebrands, J.L.4    Tio, R.A.5
  • 79
    • 0030469543 scopus 로고    scopus 로고
    • Accelerated restitution of endothelial integrity and endothelium-dependent function after phVEGF165 gene transfer
    • [79] Asahara, T., Chen, D., Tsurumi, Y., Kearney, M., Rossow, S., Passeri, J., Symes, J.F., Isner, J.M., Accelerated restitution of endothelial integrity and endothelium-dependent function after phVEGF165 gene transfer. Circulation 94:12 (1996), 3291–3302.
    • (1996) Circulation , vol.94 , Issue.12 , pp. 3291-3302
    • Asahara, T.1    Chen, D.2    Tsurumi, Y.3    Kearney, M.4    Rossow, S.5    Passeri, J.6    Symes, J.F.7    Isner, J.M.8
  • 80
    • 0035831465 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells
    • [80] Kim, I., Moon, S.O., Kim, S.H., Kim, H.J., Koh, Y.S., Koh, G.Y., Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells. J. Biol. Chem. 276:10 (2001), 7614–7620.
    • (2001) J. Biol. Chem. , vol.276 , Issue.10 , pp. 7614-7620
    • Kim, I.1    Moon, S.O.2    Kim, S.H.3    Kim, H.J.4    Koh, Y.S.5    Koh, G.Y.6
  • 81
    • 0032960891 scopus 로고    scopus 로고
    • Vascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cells
    • [81] Marumo, T., Schini-Kerth, V.B., Busse, R., Vascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cells. Diabetes 48:5 (1999), 1131–1137.
    • (1999) Diabetes , vol.48 , Issue.5 , pp. 1131-1137
    • Marumo, T.1    Schini-Kerth, V.B.2    Busse, R.3
  • 82
    • 0029867554 scopus 로고    scopus 로고
    • Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
    • [82] Barleon, B., Sozzani, S., Zhou, D., Weich, H.A., Mantovani, A., Marme, D., Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 87:8 (1996), 3336–3343.
    • (1996) Blood , vol.87 , Issue.8 , pp. 3336-3343
    • Barleon, B.1    Sozzani, S.2    Zhou, D.3    Weich, H.A.4    Mantovani, A.5    Marme, D.6
  • 85
    • 0035047885 scopus 로고    scopus 로고
    • Vascular endothelial growth factor enhances atherosclerotic plaque progression
    • [85] Celletti, F.L., Waugh, J.M., Amabile, P.G., Brendolan, A., Hilfiker, P.R., Dake, M.D., Vascular endothelial growth factor enhances atherosclerotic plaque progression. Nat. Med. 7:4 (2001), 425–429.
    • (2001) Nat. Med. , vol.7 , Issue.4 , pp. 425-429
    • Celletti, F.L.1    Waugh, J.M.2    Amabile, P.G.3    Brendolan, A.4    Hilfiker, P.R.5    Dake, M.D.6
  • 86
    • 0037022863 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is necessary in the development of arteriosclerosis by recruiting/activating monocytes in a rat model of long-term inhibition of nitric oxide synthesis
    • [86] Zhao, Q., Egashira, K., Inoue, S., Usui, M., Kitamoto, S., Ni, W., Ishibashi, M., Hiasa Ki, K., Ichiki, T., Shibuya, M., Takeshita, A., Vascular endothelial growth factor is necessary in the development of arteriosclerosis by recruiting/activating monocytes in a rat model of long-term inhibition of nitric oxide synthesis. Circulation 105:9 (2002), 1110–1115.
    • (2002) Circulation , vol.105 , Issue.9 , pp. 1110-1115
    • Zhao, Q.1    Egashira, K.2    Inoue, S.3    Usui, M.4    Kitamoto, S.5    Ni, W.6    Ishibashi, M.7    Hiasa Ki, K.8    Ichiki, T.9    Shibuya, M.10    Takeshita, A.11
  • 87
    • 24644458573 scopus 로고    scopus 로고
    • Gene transfers of vascular endothelial growth factor-A, vascular endothelial growth factor-B, vascular endothelial growth factor-C, and vascular endothelial growth factor-D have no effects on atherosclerosis in hypercholesterolemic low-density lipoprotein-receptor/apolipoprotein B48-deficient mice
    • [87] Leppanen, P., Koota, S., Kholova, I., Koponen, J., Fieber, C., Eriksson, U., Alitalo, K., Yla-Herttuala, S., Gene transfers of vascular endothelial growth factor-A, vascular endothelial growth factor-B, vascular endothelial growth factor-C, and vascular endothelial growth factor-D have no effects on atherosclerosis in hypercholesterolemic low-density lipoprotein-receptor/apolipoprotein B48-deficient mice. Circulation 112:9 (2005), 1347–1352.
    • (2005) Circulation , vol.112 , Issue.9 , pp. 1347-1352
    • Leppanen, P.1    Koota, S.2    Kholova, I.3    Koponen, J.4    Fieber, C.5    Eriksson, U.6    Alitalo, K.7    Yla-Herttuala, S.8
  • 88
    • 84862026102 scopus 로고    scopus 로고
    • VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond
    • [88] Giacca, M., Zacchigna, S., VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond. Gene Ther. 19:6 (2012), 622–629.
    • (2012) Gene Ther. , vol.19 , Issue.6 , pp. 622-629
    • Giacca, M.1    Zacchigna, S.2
  • 89
    • 84957974673 scopus 로고    scopus 로고
    • Angiogenic gene therapy for refractory angina
    • [89] Rubanyi, G.M., Angiogenic gene therapy for refractory angina. Expert Opin. Biol. Ther. 16:3 (2016), 303–315.
    • (2016) Expert Opin. Biol. Ther. , vol.16 , Issue.3 , pp. 303-315
    • Rubanyi, G.M.1
  • 90
    • 84903753621 scopus 로고    scopus 로고
    • Systematic review of the risk of adverse outcomes associated with vascular endothelial growth factor inhibitors for the treatment of cancer
    • [90] Faruque, L.I., Lin, M., Battistella, M., Wiebe, N., Reiman, T., Hemmelgarn, B., Thomas, C., Tonelli, M., Systematic review of the risk of adverse outcomes associated with vascular endothelial growth factor inhibitors for the treatment of cancer. PLoS One, 9(7), 2014, e101145.
    • (2014) PLoS One , vol.9 , Issue.7 , pp. e101145
    • Faruque, L.I.1    Lin, M.2    Battistella, M.3    Wiebe, N.4    Reiman, T.5    Hemmelgarn, B.6    Thomas, C.7    Tonelli, M.8
  • 93
    • 84903644083 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-B in physiology and disease
    • [93] Bry, M., Kivela, R., Leppanen, V.M., Alitalo, K., Vascular endothelial growth factor-B in physiology and disease. Physiol. Rev. 94:3 (2014), 779–794.
    • (2014) Physiol. Rev. , vol.94 , Issue.3 , pp. 779-794
    • Bry, M.1    Kivela, R.2    Leppanen, V.M.3    Alitalo, K.4
  • 97
    • 0026052391 scopus 로고
    • Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor
    • [97] Maglione, D., Guerriero, V., Viglietto, G., Delli-Bovi, P., Persico, M.G., Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. Proc. Natl. Acad. Sci. USA 88:20 (1991), 9267–9271.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , Issue.20 , pp. 9267-9271
    • Maglione, D.1    Guerriero, V.2    Viglietto, G.3    Delli-Bovi, P.4    Persico, M.G.5
  • 98
    • 84879288021 scopus 로고    scopus 로고
    • PlGF: a multitasking cytokine with disease-restricted activity
    • [98] Dewerchin, M., Carmeliet, P., PlGF: a multitasking cytokine with disease-restricted activity. Cold Spring Harb. Perspect. Med, 2(8), 2012.
    • (2012) Cold Spring Harb. Perspect. Med , vol.2 , Issue.8
    • Dewerchin, M.1    Carmeliet, P.2
  • 99
    • 84856874924 scopus 로고    scopus 로고
    • The discovery of placenta growth factor and its biological activity
    • [99] De Falco, S., The discovery of placenta growth factor and its biological activity. Exp. Mol. Med 44:1 (2012), 1–9.
    • (2012) Exp. Mol. Med , vol.44 , Issue.1 , pp. 1-9
    • De Falco, S.1
  • 101
    • 20344376933 scopus 로고    scopus 로고
    • Placental growth factor promotes atherosclerotic intimal thickening and macrophage accumulation
    • [101] Khurana, R., Moons, L., Shafi, S., Luttun, A., Collen, D., Martin, J.F., Carmeliet, P., Zachary, I.C., Placental growth factor promotes atherosclerotic intimal thickening and macrophage accumulation. Circulation 111:21 (2005), 2828–2836.
    • (2005) Circulation , vol.111 , Issue.21 , pp. 2828-2836
    • Khurana, R.1    Moons, L.2    Shafi, S.3    Luttun, A.4    Collen, D.5    Martin, J.F.6    Carmeliet, P.7    Zachary, I.C.8
  • 107
    • 47949083776 scopus 로고    scopus 로고
    • Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos
    • [107] Haiko, P., Makinen, T., Keskitalo, S., Taipale, J., Karkkainen, M.J., Baldwin, M.E., Stacker, S.A., Achen, M.G., Alitalo, K., Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos. Mol. Cell Biol. 28:15 (2008), 4843–4850.
    • (2008) Mol. Cell Biol. , vol.28 , Issue.15 , pp. 4843-4850
    • Haiko, P.1    Makinen, T.2    Keskitalo, S.3    Taipale, J.4    Karkkainen, M.J.5    Baldwin, M.E.6    Stacker, S.A.7    Achen, M.G.8    Alitalo, K.9
  • 113
    • 0026572345 scopus 로고
    • The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
    • [113] de Vries, C., Escobedo, J.A., Ueno, H., Houck, K., Ferrara, N., Williams, L.T., The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255:5047 (1992), 989–991.
    • (1992) Science , vol.255 , Issue.5047 , pp. 989-991
    • de Vries, C.1    Escobedo, J.A.2    Ueno, H.3    Houck, K.4    Ferrara, N.5    Williams, L.T.6
  • 115
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • [115] Soker, S., Takashima, S., Miao, H.Q., Neufeld, G., Klagsbrun, M., Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92:6 (1998), 735–745.
    • (1998) Cell , vol.92 , Issue.6 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 116
    • 84993953306 scopus 로고    scopus 로고
    • VEGF receptor signal transduction - A brief update
    • [116] Claesson-Welsh, L., VEGF receptor signal transduction - A brief update. Vasc. Pharm., 2016.
    • (2016) Vasc. Pharm.
    • Claesson-Welsh, L.1
  • 117
    • 84880742193 scopus 로고    scopus 로고
    • Signal transduction by vascular endothelial growth factor receptors
    • [117] Koch, S., Claesson-Welsh, L., Signal transduction by vascular endothelial growth factor receptors. Cold Spring Harb. Perspect. Med., 2(7), 2012, a006502.
    • (2012) Cold Spring Harb. Perspect. Med. , vol.2 , Issue.7 , pp. a006502
    • Koch, S.1    Claesson-Welsh, L.2
  • 118
    • 84871633270 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases
    • [118] Shibuya, M., Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases. J. Biochem. 153:1 (2013), 13–19.
    • (2013) J. Biochem. , vol.153 , Issue.1 , pp. 13-19
    • Shibuya, M.1
  • 122
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • [122] Fong, G.H., Rossant, J., Gertsenstein, M., Breitman, M.L., Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376:6535 (1995), 66–70.
    • (1995) Nature , vol.376 , Issue.6535 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 123
    • 0032482978 scopus 로고    scopus 로고
    • Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
    • [123] Hiratsuka, S., Minowa, O., Kuno, J., Noda, T., Shibuya, M., Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc. Natl. Acad. Sci. USA 95:16 (1998), 9349–9354.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.16 , pp. 9349-9354
    • Hiratsuka, S.1    Minowa, O.2    Kuno, J.3    Noda, T.4    Shibuya, M.5
  • 125
    • 36749103151 scopus 로고    scopus 로고
    • Ligand-independent activation of vascular endothelial growth factor receptor 1 by low-density lipoprotein
    • [125] Usui, R., Shibuya, M., Ishibashi, S., Maru, Y., Ligand-independent activation of vascular endothelial growth factor receptor 1 by low-density lipoprotein. EMBO Rep. 8:12 (2007), 1155–1161.
    • (2007) EMBO Rep. , vol.8 , Issue.12 , pp. 1155-1161
    • Usui, R.1    Shibuya, M.2    Ishibashi, S.3    Maru, Y.4
  • 126
    • 34447310236 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis
    • (discussion 231)
    • [126] Shibuya, M., Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis. Angiogenesis 9:4 (2006), 225–230 (discussion 231).
    • (2006) Angiogenesis , vol.9 , Issue.4 , pp. 225-230
    • Shibuya, M.1
  • 129
    • 34247339635 scopus 로고    scopus 로고
    • DNA vaccination against VEGF receptor 2 reduces atherosclerosis in LDL receptor-deficient mice
    • [129] Petrovan, R.J., Kaplan, C.D., Reisfeld, R.A., Curtiss, L.K., DNA vaccination against VEGF receptor 2 reduces atherosclerosis in LDL receptor-deficient mice. Arterioscler Thromb. Vasc. Biol. 27:5 (2007), 1095–1100.
    • (2007) Arterioscler Thromb. Vasc. Biol. , vol.27 , Issue.5 , pp. 1095-1100
    • Petrovan, R.J.1    Kaplan, C.D.2    Reisfeld, R.A.3    Curtiss, L.K.4
  • 131
    • 77952310126 scopus 로고    scopus 로고
    • Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials
    • [131] Choueiri, T.K., Schutz, F.A., Je, Y., Rosenberg, J.E., Bellmunt, J., Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. J. Clin. Oncol. 28:13 (2010), 2280–2285.
    • (2010) J. Clin. Oncol. , vol.28 , Issue.13 , pp. 2280-2285
    • Choueiri, T.K.1    Schutz, F.A.2    Je, Y.3    Rosenberg, J.E.4    Bellmunt, J.5
  • 132
    • 0026695259 scopus 로고
    • tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors
    • [132] Dumont, D.J., Yamaguchi, T.P., Conlon, R.A., Rossant, J., Breitman, M.L., tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors. Oncogene 7:8 (1992), 1471–1480.
    • (1992) Oncogene , vol.7 , Issue.8 , pp. 1471-1480
    • Dumont, D.J.1    Yamaguchi, T.P.2    Conlon, R.A.3    Rossant, J.4    Breitman, M.L.5
  • 136
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • [136] Hanahan, D., Signaling vascular morphogenesis and maintenance. Science 277:5322 (1997), 48–50.
    • (1997) Science , vol.277 , Issue.5322 , pp. 48-50
    • Hanahan, D.1
  • 137
    • 0034648793 scopus 로고    scopus 로고
    • Vascular-specific growth factors and blood vessel formation
    • [137] Yancopoulos, G.D., Davis, S., Gale, N.W., Rudge, J.S., Wiegand, S.J., Holash, J., Vascular-specific growth factors and blood vessel formation. Nature 407:6801 (2000), 242–248.
    • (2000) Nature , vol.407 , Issue.6801 , pp. 242-248
    • Yancopoulos, G.D.1    Davis, S.2    Gale, N.W.3    Rudge, J.S.4    Wiegand, S.J.5    Holash, J.6
  • 138
    • 0242405592 scopus 로고    scopus 로고
    • Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis
    • [138] Thurston, G., Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis. Cell Tissue Res. 314:1 (2003), 61–68.
    • (2003) Cell Tissue Res. , vol.314 , Issue.1 , pp. 61-68
    • Thurston, G.1
  • 139
    • 60749096085 scopus 로고    scopus 로고
    • Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system
    • [139] Augustin, H.G., Koh, G.Y., Thurston, G., Alitalo, K., Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat. Rev. Mol. Cell Biol. 10:3 (2009), 165–177.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , Issue.3 , pp. 165-177
    • Augustin, H.G.1    Koh, G.Y.2    Thurston, G.3    Alitalo, K.4
  • 140
    • 84888301087 scopus 로고    scopus 로고
    • The angiopoietin: tie 2 interaction: a potential target for future therapies in human vascular disease
    • [140] Moss, A., The angiopoietin: tie 2 interaction: a potential target for future therapies in human vascular disease. Cytokine Growth Factor Rev. 24:6 (2013), 579–592.
    • (2013) Cytokine Growth Factor Rev. , vol.24 , Issue.6 , pp. 579-592
    • Moss, A.1
  • 141
    • 0028122465 scopus 로고
    • Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
    • [141] Dumont, D.J., Gradwohl, G., Fong, G.H., Puri, M.C., Gertsenstein, M., Auerbach, A., Breitman, M.L., Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev. 8:16 (1994), 1897–1909.
    • (1994) Genes Dev. , vol.8 , Issue.16 , pp. 1897-1909
    • Dumont, D.J.1    Gradwohl, G.2    Fong, G.H.3    Puri, M.C.4    Gertsenstein, M.5    Auerbach, A.6    Breitman, M.L.7
  • 142
    • 0030480322 scopus 로고    scopus 로고
    • Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
    • [142] Suri, C., Jones, P.F., Patan, S., Bartunkova, S., Maisonpierre, P.C., Davis, S., Sato, T.N., Yancopoulos, G.D., Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87:7 (1996), 1171–1180.
    • (1996) Cell , vol.87 , Issue.7 , pp. 1171-1180
    • Suri, C.1    Jones, P.F.2    Patan, S.3    Bartunkova, S.4    Maisonpierre, P.C.5    Davis, S.6    Sato, T.N.7    Yancopoulos, G.D.8
  • 145
    • 0028867704 scopus 로고
    • The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells
    • [145] Puri, M.C., Rossant, J., Alitalo, K., Bernstein, A., Partanen, J., The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. EMBO J. 14:23 (1995), 5884–5891.
    • (1995) EMBO J. , vol.14 , Issue.23 , pp. 5884-5891
    • Puri, M.C.1    Rossant, J.2    Alitalo, K.3    Bernstein, A.4    Partanen, J.5
  • 148
    • 80052776607 scopus 로고    scopus 로고
    • Multiple roles of angiopoietins in atherogenesis
    • [148] Ahmed, A., Fujisawa, T., Multiple roles of angiopoietins in atherogenesis. Curr. Opin. Lipido. 22:5 (2011), 380–385.
    • (2011) Curr. Opin. Lipido. , vol.22 , Issue.5 , pp. 380-385
    • Ahmed, A.1    Fujisawa, T.2
  • 152
    • 79953304687 scopus 로고    scopus 로고
    • Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific manner
    • [152] Woo, K.V., Qu, X., Babaev, V.R., Linton, M.F., Guzman, R.J., Fazio, S., Baldwin, H.S., Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific manner. J. Clin. Invest 121:4 (2011), 1624–1635.
    • (2011) J. Clin. Invest , vol.121 , Issue.4 , pp. 1624-1635
    • Woo, K.V.1    Qu, X.2    Babaev, V.R.3    Linton, M.F.4    Guzman, R.J.5    Fazio, S.6    Baldwin, H.S.7
  • 155
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • [155] Furchgott, R.F., Zawadzki, J.V., The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:5789 (1980), 373–376.
    • (1980) Nature , vol.288 , Issue.5789 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 156
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • [156] Ignarro, L.J., Buga, G.M., Wood, K.S., Byrns, R.E., Chaudhuri, G., Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Natl. Acad. Sci. USA 84:24 (1987), 9265–9269.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , Issue.24 , pp. 9265-9269
    • Ignarro, L.J.1    Buga, G.M.2    Wood, K.S.3    Byrns, R.E.4    Chaudhuri, G.5
  • 157
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • [157] Palmer, R.M., Ferrige, A.G., Moncada, S., Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327:6122 (1987), 524–526.
    • (1987) Nature , vol.327 , Issue.6122 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 158
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: structure, function and inhibition
    • [158] Alderton, W.K., Cooper, C.E., Knowles, R.G., Nitric oxide synthases: structure, function and inhibition. Biochem. J. 357:Pt 3 (2001), 593–615.
    • (2001) Biochem. J. , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 159
    • 1242341462 scopus 로고    scopus 로고
    • NO and angiogenesis
    • [159] Cooke, J.P., NO and angiogenesis. Atheroscler. Suppl. 4:4 (2003), 53–60.
    • (2003) Atheroscler. Suppl. , vol.4 , Issue.4 , pp. 53-60
    • Cooke, J.P.1
  • 160
    • 84859487532 scopus 로고    scopus 로고
    • Nitric oxide synthases: regulation and function
    • (837a-837d)
    • [160] Forstermann, U., Sessa, W.C., Nitric oxide synthases: regulation and function. Eur. Heart J. 33:7 (2012), 829–837 (837a-837d).
    • (2012) Eur. Heart J. , vol.33 , Issue.7 , pp. 829-837
    • Forstermann, U.1    Sessa, W.C.2
  • 161
    • 84978062956 scopus 로고    scopus 로고
    • Thirty Years of Saying NO: sources, Fate, Actions, and Misfortunes of the Endothelium-Derived Vasodilator Mediator
    • [161] Vanhoutte, P.M., Zhao, Y., Xu, A., Leung, S.W., Thirty Years of Saying NO: sources, Fate, Actions, and Misfortunes of the Endothelium-Derived Vasodilator Mediator. Circ. Res. 119:2 (2016), 375–396.
    • (2016) Circ. Res. , vol.119 , Issue.2 , pp. 375-396
    • Vanhoutte, P.M.1    Zhao, Y.2    Xu, A.3    Leung, S.W.4
  • 162
    • 0027769462 scopus 로고
    • Targeted disruption of the neuronal nitric oxide synthase gene
    • [162] Huang, P.L., Dawson, T.M., Bredt, D.S., Snyder, S.H., Fishman, M.C., Targeted disruption of the neuronal nitric oxide synthase gene. Cell 75:7 (1993), 1273–1286.
    • (1993) Cell , vol.75 , Issue.7 , pp. 1273-1286
    • Huang, P.L.1    Dawson, T.M.2    Bredt, D.S.3    Snyder, S.H.4    Fishman, M.C.5
  • 164
    • 0029021148 scopus 로고
    • Hypertension in mice lacking the gene for endothelial nitric oxide synthase
    • [164] Huang, P.L., Huang, Z., Mashimo, H., Bloch, K.D., Moskowitz, M.A., Bevan, J.A., Fishman, M.C., Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377:6546 (1995), 239–242.
    • (1995) Nature , vol.377 , Issue.6546 , pp. 239-242
    • Huang, P.L.1    Huang, Z.2    Mashimo, H.3    Bloch, K.D.4    Moskowitz, M.A.5    Bevan, J.A.6    Fishman, M.C.7
  • 165
    • 0035943042 scopus 로고    scopus 로고
    • Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice
    • [165] Kuhlencordt, P.J., Gyurko, R., Han, F., Scherrer-Crosbie, M., Aretz, T.H., Hajjar, R., Picard, M.H., Huang, P.L., Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice. Circulation 104:4 (2001), 448–454.
    • (2001) Circulation , vol.104 , Issue.4 , pp. 448-454
    • Kuhlencordt, P.J.1    Gyurko, R.2    Han, F.3    Scherrer-Crosbie, M.4    Aretz, T.H.5    Hajjar, R.6    Picard, M.H.7    Huang, P.L.8
  • 166
    • 0034687141 scopus 로고    scopus 로고
    • Angiogenesis is impaired by hypercholesterolemia: role of asymmetric dimethylarginine
    • [166] Jang, J.J., Ho, H.K., Kwan, H.H., Fajardo, L.F., Cooke, J.P., Angiogenesis is impaired by hypercholesterolemia: role of asymmetric dimethylarginine. Circulation 102:12 (2000), 1414–1419.
    • (2000) Circulation , vol.102 , Issue.12 , pp. 1414-1419
    • Jang, J.J.1    Ho, H.K.2    Kwan, H.H.3    Fajardo, L.F.4    Cooke, J.P.5
  • 169
    • 0028889439 scopus 로고
    • Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death
    • [169] Laubach, V.E., Shesely, E.G., Smithies, O., Sherman, P.A., Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death. Proc. Natl. Acad. Sci. USA 92:23 (1995), 10688–10692.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , Issue.23 , pp. 10688-10692
    • Laubach, V.E.1    Shesely, E.G.2    Smithies, O.3    Sherman, P.A.4
  • 170
  • 172
    • 38849198659 scopus 로고    scopus 로고
    • Cardiovascular roles of nitric oxide: a review of insights from nitric oxide synthase gene disrupted mice
    • [172] Liu, V.W., Huang, P.L., Cardiovascular roles of nitric oxide: a review of insights from nitric oxide synthase gene disrupted mice. Cardiovasc. Res. 77:1 (2008), 19–29.
    • (2008) Cardiovasc. Res. , vol.77 , Issue.1 , pp. 19-29
    • Liu, V.W.1    Huang, P.L.2
  • 174
    • 0035954312 scopus 로고    scopus 로고
    • Genetic deficiency of inducible nitric oxide synthase reduces atherosclerosis and lowers plasma lipid peroxides in apolipoprotein E-knockout mice
    • [174] Kuhlencordt, P.J., Chen, J., Han, F., Astern, J., Huang, P.L., Genetic deficiency of inducible nitric oxide synthase reduces atherosclerosis and lowers plasma lipid peroxides in apolipoprotein E-knockout mice. Circulation 103:25 (2001), 3099–3104.
    • (2001) Circulation , vol.103 , Issue.25 , pp. 3099-3104
    • Kuhlencordt, P.J.1    Chen, J.2    Han, F.3    Astern, J.4    Huang, P.L.5
  • 176
    • 77952891786 scopus 로고    scopus 로고
    • Nitric oxide synthases in the pathogenesis of cardiovascular disease: lessons from genetically modified mice
    • [176] Shimokawa, H., Tsutsui, M., Nitric oxide synthases in the pathogenesis of cardiovascular disease: lessons from genetically modified mice. Pflug. Arch. 459:6 (2010), 959–967.
    • (2010) Pflug. Arch. , vol.459 , Issue.6 , pp. 959-967
    • Shimokawa, H.1    Tsutsui, M.2
  • 180
    • 0033965483 scopus 로고    scopus 로고
    • Akt takes center stage in angiogenesis signaling
    • [180] Dimmeler, S., Zeiher, A.M., Akt takes center stage in angiogenesis signaling. Circ. Res. 86:1 (2000), 4–5.
    • (2000) Circ. Res. , vol.86 , Issue.1 , pp. 4-5
    • Dimmeler, S.1    Zeiher, A.M.2
  • 182
    • 84990224963 scopus 로고    scopus 로고
    • beta2-Glycoprotein I Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis by Suppressing the Phosphorylation of Extracellular Signal-Regulated Kinase 1/2, Akt, and Endothelial Nitric Oxide Synthase
    • [182] Chiu, W.C., Chiou, T.J., Chung, M.J., Chiang, A.N., beta2-Glycoprotein I Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis by Suppressing the Phosphorylation of Extracellular Signal-Regulated Kinase 1/2, Akt, and Endothelial Nitric Oxide Synthase. PLoS One, 11(8), 2016, e0161950.
    • (2016) PLoS One , vol.11 , Issue.8 , pp. e0161950
    • Chiu, W.C.1    Chiou, T.J.2    Chung, M.J.3    Chiang, A.N.4
  • 183
    • 84985034253 scopus 로고    scopus 로고
    • Identification of resveratrol derivative 3,3',4,4',5,5'-hexamethoxy- trans-stilbene as a novel pro-angiogenic small-molecule compound
    • [183] Chen, Z., Zhang, L., Yu, J., Chen, L., Zhou, B., Identification of resveratrol derivative 3,3',4,4',5,5'-hexamethoxy- trans-stilbene as a novel pro-angiogenic small-molecule compound. Eur. J. Pharm. 791 (2016), 185–194.
    • (2016) Eur. J. Pharm. , vol.791 , pp. 185-194
    • Chen, Z.1    Zhang, L.2    Yu, J.3    Chen, L.4    Zhou, B.5
  • 184
    • 84907312920 scopus 로고    scopus 로고
    • Vasa vasorum anti-angiogenesis through H(2)O(2), HIF-1alpha, NF-kappaB, and iNOS inhibition by mangosteen pericarp ethanolic extract (Garcinia mangostana Linn) in hypercholesterol-diet-given Rattus norvegicus Wistar strain
    • [184] Wihastuti, T.A., Sargowo, D., Tjokroprawiro, A., Permatasari, N., Widodo, M.A., Soeharto, S., Vasa vasorum anti-angiogenesis through H(2)O(2), HIF-1alpha, NF-kappaB, and iNOS inhibition by mangosteen pericarp ethanolic extract (Garcinia mangostana Linn) in hypercholesterol-diet-given Rattus norvegicus Wistar strain. Vasc. Health Risk Manag. 10 (2014), 523–531.
    • (2014) Vasc. Health Risk Manag. , vol.10 , pp. 523-531
    • Wihastuti, T.A.1    Sargowo, D.2    Tjokroprawiro, A.3    Permatasari, N.4    Widodo, M.A.5    Soeharto, S.6
  • 185
    • 84991269679 scopus 로고    scopus 로고
    • Altered Nitric Oxide System in Cardiovascular and Renal Diseases
    • [185] Lee, J., Bae, E.H., Ma, S.K., Kim, S.W., Altered Nitric Oxide System in Cardiovascular and Renal Diseases. Chonnam Med. J. 52:2 (2016), 81–90.
    • (2016) Chonnam Med. J. , vol.52 , Issue.2 , pp. 81-90
    • Lee, J.1    Bae, E.H.2    Ma, S.K.3    Kim, S.W.4
  • 186
    • 84957636905 scopus 로고    scopus 로고
    • The expanding role of neuropilin: regulation of transforming growth factor-beta and platelet-derived growth factor signaling in the vasculature
    • [186] Kofler, N., Simons, M., The expanding role of neuropilin: regulation of transforming growth factor-beta and platelet-derived growth factor signaling in the vasculature. Curr. Opin. Hematol. 23:3 (2016), 260–267.
    • (2016) Curr. Opin. Hematol. , vol.23 , Issue.3 , pp. 260-267
    • Kofler, N.1    Simons, M.2
  • 187
    • 0027936261 scopus 로고
    • Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities
    • [187] Leveen, P., Pekny, M., Gebre-Medhin, S., Swolin, B., Larsson, E., Betsholtz, C., Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities. Genes Dev. 8:16 (1994), 1875–1887.
    • (1994) Genes Dev. , vol.8 , Issue.16 , pp. 1875-1887
    • Leveen, P.1    Pekny, M.2    Gebre-Medhin, S.3    Swolin, B.4    Larsson, E.5    Betsholtz, C.6
  • 188
    • 0028059309 scopus 로고
    • Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice
    • [188] Soriano, P., Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. Genes Dev. 8:16 (1994), 1888–1896.
    • (1994) Genes Dev. , vol.8 , Issue.16 , pp. 1888-1896
    • Soriano, P.1
  • 189
    • 0030756325 scopus 로고    scopus 로고
    • Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
    • [189] Lindahl, P., Johansson, B.R., Leveen, P., Betsholtz, C., Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 277:5323 (1997), 242–245.
    • (1997) Science , vol.277 , Issue.5323 , pp. 242-245
    • Lindahl, P.1    Johansson, B.R.2    Leveen, P.3    Betsholtz, C.4
  • 190
    • 0032768156 scopus 로고    scopus 로고
    • Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
    • [190] Hellstrom, M., Kalen, M., Lindahl, P., Abramsson, A., Betsholtz, C., Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development 126:14 (1999), 3047–3055.
    • (1999) Development , vol.126 , Issue.14 , pp. 3047-3055
    • Hellstrom, M.1    Kalen, M.2    Lindahl, P.3    Abramsson, A.4    Betsholtz, C.5
  • 192
    • 77950024231 scopus 로고    scopus 로고
    • A comparative study of carotid atherosclerotic plaque microvessel density and angiogenic growth factor expression in symptomatic versus asymptomatic patients
    • [192] Chowdhury, M., Ghosh, J., Slevin, M., Smyth, J.V., Alexander, M.Y., Serracino-Inglott, F., A comparative study of carotid atherosclerotic plaque microvessel density and angiogenic growth factor expression in symptomatic versus asymptomatic patients. Eur. J. Vasc. Endovasc. Surg. 39:4 (2010), 388–395.
    • (2010) Eur. J. Vasc. Endovasc. Surg. , vol.39 , Issue.4 , pp. 388-395
    • Chowdhury, M.1    Ghosh, J.2    Slevin, M.3    Smyth, J.V.4    Alexander, M.Y.5    Serracino-Inglott, F.6
  • 194
    • 0031106404 scopus 로고    scopus 로고
    • Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity
    • [194] Pepper, M.S., Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity. Cytokine Growth Factor Rev. 8:1 (1997), 21–43.
    • (1997) Cytokine Growth Factor Rev. , vol.8 , Issue.1 , pp. 21-43
    • Pepper, M.S.1
  • 195
    • 62149102642 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 (TGF-beta1) induces angiogenesis through vascular endothelial growth factor (VEGF)-mediated apoptosis
    • [195] Ferrari, G., Cook, B.D., Terushkin, V., Pintucci, G., Mignatti, P., Transforming growth factor-beta 1 (TGF-beta1) induces angiogenesis through vascular endothelial growth factor (VEGF)-mediated apoptosis. J. Cell Physiol. 219:2 (2009), 449–458.
    • (2009) J. Cell Physiol. , vol.219 , Issue.2 , pp. 449-458
    • Ferrari, G.1    Cook, B.D.2    Terushkin, V.3    Pintucci, G.4    Mignatti, P.5
  • 196
    • 0032482202 scopus 로고    scopus 로고
    • PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate
    • [196] Hirschi, K.K., Rohovsky, S.A., D'Amore, P.A., PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate. J. Cell Biol. 141:3 (1998), 805–814.
    • (1998) J. Cell Biol. , vol.141 , Issue.3 , pp. 805-814
    • Hirschi, K.K.1    Rohovsky, S.A.2    D'Amore, P.A.3
  • 197
    • 33751207110 scopus 로고    scopus 로고
    • VEGF, a prosurvival factor, acts in concert with TGF-beta1 to induce endothelial cell apoptosis
    • [197] Ferrari, G., Pintucci, G., Seghezzi, G., Hyman, K., Galloway, A.C., Mignatti, P., VEGF, a prosurvival factor, acts in concert with TGF-beta1 to induce endothelial cell apoptosis. Proc. Natl. Acad. Sci. USA 103:46 (2006), 17260–17265.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , Issue.46 , pp. 17260-17265
    • Ferrari, G.1    Pintucci, G.2    Seghezzi, G.3    Hyman, K.4    Galloway, A.C.5    Mignatti, P.6
  • 198
    • 0036789313 scopus 로고    scopus 로고
    • The role of fibroblast growth factors in vascular development
    • [198] Javerzat, S., Auguste, P., Bikfalvi, A., The role of fibroblast growth factors in vascular development. Trends Mol. Med. 8:10 (2002), 483–489.
    • (2002) Trends Mol. Med. , vol.8 , Issue.10 , pp. 483-489
    • Javerzat, S.1    Auguste, P.2    Bikfalvi, A.3
  • 199
    • 33645845521 scopus 로고    scopus 로고
    • The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis
    • [199] Dreux, A.C., Lamb, D.J., Modjtahedi, H., Ferns, G.A., The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis. Atherosclerosis 186:1 (2006), 38–53.
    • (2006) Atherosclerosis , vol.186 , Issue.1 , pp. 38-53
    • Dreux, A.C.1    Lamb, D.J.2    Modjtahedi, H.3    Ferns, G.A.4
  • 200
    • 57249114643 scopus 로고    scopus 로고
    • HB-EGF stimulates eNOS expression and nitric oxide production and promotes eNOS dependent angiogenesis
    • [200] Mehta, V.B., Zhou, Y., Radulescu, A., Besner, G.E., HB-EGF stimulates eNOS expression and nitric oxide production and promotes eNOS dependent angiogenesis. Growth Factors 26:6 (2008), 301–315.
    • (2008) Growth Factors , vol.26 , Issue.6 , pp. 301-315
    • Mehta, V.B.1    Zhou, Y.2    Radulescu, A.3    Besner, G.E.4
  • 202
    • 84883809887 scopus 로고    scopus 로고
    • IC-4, a new irreversible EGFR inhibitor, exhibits prominent anti-tumor and anti-angiogenesis activities
    • [202] Li, Y.B., Wang, Z.Q., Yan, X., Chen, M.W., Bao, J.L., Wu, G.S., Ge, Z.M., Zhou, D.M., Wang, Y.T., Li, R.T., IC-4, a new irreversible EGFR inhibitor, exhibits prominent anti-tumor and anti-angiogenesis activities. Cancer Lett. 340:1 (2013), 88–96.
    • (2013) Cancer Lett. , vol.340 , Issue.1 , pp. 88-96
    • Li, Y.B.1    Wang, Z.Q.2    Yan, X.3    Chen, M.W.4    Bao, J.L.5    Wu, G.S.6    Ge, Z.M.7    Zhou, D.M.8    Wang, Y.T.9    Li, R.T.10
  • 203
    • 84886736125 scopus 로고    scopus 로고
    • Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer
    • [203] Khong, T.L., Thairu, N., Larsen, H., Dawson, P.M., Kiriakidis, S., Paleolog, E.M., Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer. BMC Cancer, 13, 2013, 518.
    • (2013) BMC Cancer , vol.13 , pp. 518
    • Khong, T.L.1    Thairu, N.2    Larsen, H.3    Dawson, P.M.4    Kiriakidis, S.5    Paleolog, E.M.6
  • 204
    • 84868569679 scopus 로고    scopus 로고
    • Post-translational regulation of sphingosine kinases
    • [204] Chan, H., Pitson, S.M., Post-translational regulation of sphingosine kinases. Biochim Biophys. Acta 1831:1 (2013), 147–156.
    • (2013) Biochim Biophys. Acta , vol.1831 , Issue.1 , pp. 147-156
    • Chan, H.1    Pitson, S.M.2
  • 207
    • 0038218405 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate: an enigmatic signalling lipid
    • [207] Spiegel, S., Milstien, S., Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat. Rev. Mol. Cell Biol. 4:5 (2003), 397–407.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , Issue.5 , pp. 397-407
    • Spiegel, S.1    Milstien, S.2
  • 208
    • 33747588567 scopus 로고    scopus 로고
    • Cellular signalling by sphingosine kinase and sphingosine 1-phosphate
    • [208] Leclercq, T.M., Pitson, S.M., Cellular signalling by sphingosine kinase and sphingosine 1-phosphate. IUBMB Life 58:8 (2006), 467–472.
    • (2006) IUBMB Life , vol.58 , Issue.8 , pp. 467-472
    • Leclercq, T.M.1    Pitson, S.M.2
  • 209
    • 84855303523 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate signaling and its role in disease
    • [209] Maceyka, M., Harikumar, K.B., Milstien, S., Spiegel, S., Sphingosine-1-phosphate signaling and its role in disease. Trends Cell Biol. 22:1 (2012), 50–60.
    • (2012) Trends Cell Biol. , vol.22 , Issue.1 , pp. 50-60
    • Maceyka, M.1    Harikumar, K.B.2    Milstien, S.3    Spiegel, S.4
  • 210
    • 84926293921 scopus 로고    scopus 로고
    • Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy
    • [210] Proia, R.L., Hla, T., Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy. J. Clin. Invest 125:4 (2015), 1379–1387.
    • (2015) J. Clin. Invest , vol.125 , Issue.4 , pp. 1379-1387
    • Proia, R.L.1    Hla, T.2
  • 211
    • 3142744111 scopus 로고    scopus 로고
    • The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis
    • [211] Kono, M., Mi, Y., Liu, Y., Sasaki, T., Allende, M.L., Wu, Y.P., Yamashita, T., Proia, R.L., The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis. J. Biol. Chem. 279:28 (2004), 29367–29373.
    • (2004) J. Biol. Chem. , vol.279 , Issue.28 , pp. 29367-29373
    • Kono, M.1    Mi, Y.2    Liu, Y.3    Sasaki, T.4    Allende, M.L.5    Wu, Y.P.6    Yamashita, T.7    Proia, R.L.8
  • 212
    • 0037162037 scopus 로고    scopus 로고
    • Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors
    • [212] Kluk, M.J., Hla, T., Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors. Biochim Biophys. Acta 1582:1–3 (2002), 72–80.
    • (2002) Biochim Biophys. Acta , vol.1582 , Issue.1-3 , pp. 72-80
    • Kluk, M.J.1    Hla, T.2
  • 214
    • 77957587138 scopus 로고    scopus 로고
    • A novel sphingosine-1-phosphate receptor 1 antagonist prevents the proliferation and relaxation of vascular endothelial cells by sphingosine-1-phosphate
    • [214] Yonesu, K., Nakamura, T., Mizuno, Y., Suzuki, C., Nagayama, T., Satoh, S., Nara, F., A novel sphingosine-1-phosphate receptor 1 antagonist prevents the proliferation and relaxation of vascular endothelial cells by sphingosine-1-phosphate. Biol. Pharm. Bull. 33:9 (2010), 1500–1505.
    • (2010) Biol. Pharm. Bull. , vol.33 , Issue.9 , pp. 1500-1505
    • Yonesu, K.1    Nakamura, T.2    Mizuno, Y.3    Suzuki, C.4    Nagayama, T.5    Satoh, S.6    Nara, F.7
  • 215
    • 0037044854 scopus 로고    scopus 로고
    • Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS)
    • [215] Tanimoto, T., Jin, Z.G., Berk, B.C., Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS). J. Biol. Chem. 277:45 (2002), 42997–43001.
    • (2002) J. Biol. Chem. , vol.277 , Issue.45 , pp. 42997-43001
    • Tanimoto, T.1    Jin, Z.G.2    Berk, B.C.3
  • 216
    • 67449132285 scopus 로고    scopus 로고
    • Regulation of vascular physiology and pathology by the S1P2 receptor subtype
    • [216] Skoura, A., Hla, T., Regulation of vascular physiology and pathology by the S1P2 receptor subtype. Cardiovasc. Res. 82:2 (2009), 221–228.
    • (2009) Cardiovasc. Res. , vol.82 , Issue.2 , pp. 221-228
    • Skoura, A.1    Hla, T.2
  • 217
    • 84889670659 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate receptor 2
    • [217] Adada, M., Canals, D., Hannun, Y.A., Obeid, L.M., Sphingosine-1-phosphate receptor 2. FEBS J. 280:24 (2013), 6354–6366.
    • (2013) FEBS J. , vol.280 , Issue.24 , pp. 6354-6366
    • Adada, M.1    Canals, D.2    Hannun, Y.A.3    Obeid, L.M.4
  • 219
    • 0034658614 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3
    • [219] Kimura, T., Watanabe, T., Sato, K., Kon, J., Tomura, H., Tamama, K., Kuwabara, A., Kanda, T., Kobayashi, I., Ohta, H., Ui, M., Okajima, F., Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3. Biochem. J. 348:Pt 1 (2000), 71–76.
    • (2000) Biochem. J. , vol.348 , pp. 71-76
    • Kimura, T.1    Watanabe, T.2    Sato, K.3    Kon, J.4    Tomura, H.5    Tamama, K.6    Kuwabara, A.7    Kanda, T.8    Kobayashi, I.9    Ohta, H.10    Ui, M.11    Okajima, F.12
  • 221
    • 0032788539 scopus 로고    scopus 로고
    • Neovascularization in early atherosclerotic lesions of human carotid arteries: its potential contribution to plaque development
    • [221] Jeziorska, M., Woolley, D.E., Neovascularization in early atherosclerotic lesions of human carotid arteries: its potential contribution to plaque development. Hum. Pathol. 30:8 (1999), 919–925.
    • (1999) Hum. Pathol. , vol.30 , Issue.8 , pp. 919-925
    • Jeziorska, M.1    Woolley, D.E.2
  • 222
    • 84930703242 scopus 로고    scopus 로고
    • The vasa vasorum in atherosclerosis: the vessel within the vascular wall
    • [222] Kwon, T.G., Lerman, L.O., Lerman, A., The vasa vasorum in atherosclerosis: the vessel within the vascular wall. J. Am. Coll. Cardiol. 65:23 (2015), 2478–2480.
    • (2015) J. Am. Coll. Cardiol. , vol.65 , Issue.23 , pp. 2478-2480
    • Kwon, T.G.1    Lerman, L.O.2    Lerman, A.3
  • 224
    • 84925851378 scopus 로고    scopus 로고
    • A century of cholesterol and coronaries: from plaques to genes to statins
    • [224] Goldstein, J.L., Brown, M.S., A century of cholesterol and coronaries: from plaques to genes to statins. Cell 161:1 (2015), 161–172.
    • (2015) Cell , vol.161 , Issue.1 , pp. 161-172
    • Goldstein, J.L.1    Brown, M.S.2
  • 225
    • 55749083068 scopus 로고    scopus 로고
    • NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes
    • [225] Infante, R.E., Wang, M.L., Radhakrishnan, A., Kwon, H.J., Brown, M.S., Goldstein, J.L., NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes. Proc. Natl. Acad. Sci. USA 105:40 (2008), 15287–15292.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , Issue.40 , pp. 15287-15292
    • Infante, R.E.1    Wang, M.L.2    Radhakrishnan, A.3    Kwon, H.J.4    Brown, M.S.5    Goldstein, J.L.6
  • 227
    • 79951847932 scopus 로고    scopus 로고
    • Cholesterol regulates VEGFR-1 (FLT-1) expression and signaling in acute leukemia cells
    • [227] Casalou, C., Costa, A., Carvalho, T., Gomes, A.L., Zhu, Z., Wu, Y., Dias, S., Cholesterol regulates VEGFR-1 (FLT-1) expression and signaling in acute leukemia cells. Mol. Cancer Res. 9:2 (2011), 215–224.
    • (2011) Mol. Cancer Res. , vol.9 , Issue.2 , pp. 215-224
    • Casalou, C.1    Costa, A.2    Carvalho, T.3    Gomes, A.L.4    Zhu, Z.5    Wu, Y.6    Dias, S.7
  • 228
    • 39749190679 scopus 로고    scopus 로고
    • Caveolin-1 interacts and cooperates with the transforming growth factor-beta type I receptor ALK1 in endothelial caveolae
    • [228] Santibanez, J.F., Blanco, F.J., Garrido-Martin, E.M., Sanz-Rodriguez, F., del Pozo, M.A., Bernabeu, C., Caveolin-1 interacts and cooperates with the transforming growth factor-beta type I receptor ALK1 in endothelial caveolae. Cardiovasc. Res. 77:4 (2008), 791–799.
    • (2008) Cardiovasc. Res. , vol.77 , Issue.4 , pp. 791-799
    • Santibanez, J.F.1    Blanco, F.J.2    Garrido-Martin, E.M.3    Sanz-Rodriguez, F.4    del Pozo, M.A.5    Bernabeu, C.6
  • 232
    • 0030853575 scopus 로고    scopus 로고
    • Hypercholesterolemia attenuates angiogenesis but does not preclude augmentation by angiogenic cytokines
    • [232] Van Belle, E., Rivard, A., Chen, D., Silver, M., Bunting, S., Ferrara, N., Symes, J.F., Bauters, C., Isner, J.M., Hypercholesterolemia attenuates angiogenesis but does not preclude augmentation by angiogenic cytokines. Circulation 96:8 (1997), 2667–2674.
    • (1997) Circulation , vol.96 , Issue.8 , pp. 2667-2674
    • Van Belle, E.1    Rivard, A.2    Chen, D.3    Silver, M.4    Bunting, S.5    Ferrara, N.6    Symes, J.F.7    Bauters, C.8    Isner, J.M.9
  • 234
    • 31044447649 scopus 로고    scopus 로고
    • Hypercholesterolemia impairs the myocardial angiogenic response in a swine model of chronic ischemia: role of endostatin and oxidative stress
    • [234] Boodhwani, M., Nakai, Y., Mieno, S., Voisine, P., Bianchi, C., Araujo, E.G., Feng, J., Michael, K., Li, J., Sellke, F.W., Hypercholesterolemia impairs the myocardial angiogenic response in a swine model of chronic ischemia: role of endostatin and oxidative stress. Ann. Thorac. Surg. 81:2 (2006), 634–641.
    • (2006) Ann. Thorac. Surg. , vol.81 , Issue.2 , pp. 634-641
    • Boodhwani, M.1    Nakai, Y.2    Mieno, S.3    Voisine, P.4    Bianchi, C.5    Araujo, E.G.6    Feng, J.7    Michael, K.8    Li, J.9    Sellke, F.W.10
  • 235
    • 79960699752 scopus 로고    scopus 로고
    • Nox2-derived reactive oxygen species contribute to hypercholesterolemia-induced inhibition of neovascularization: effects on endothelial progenitor cells and mature endothelial cells
    • [235] Haddad, P., Dussault, S., Groleau, J., Turgeon, J., Maingrette, F., Rivard, A., Nox2-derived reactive oxygen species contribute to hypercholesterolemia-induced inhibition of neovascularization: effects on endothelial progenitor cells and mature endothelial cells. Atherosclerosis 217:2 (2011), 340–349.
    • (2011) Atherosclerosis , vol.217 , Issue.2 , pp. 340-349
    • Haddad, P.1    Dussault, S.2    Groleau, J.3    Turgeon, J.4    Maingrette, F.5    Rivard, A.6
  • 236
    • 84879246715 scopus 로고    scopus 로고
    • LDL attenuates VEGF-induced angiogenesis via mechanisms involving VEGFR2 internalization and degradation following endosome-trans-Golgi network trafficking
    • [236] Jin, F., Hagemann, N., Brockmeier, U., Schafer, S.T., Zechariah, A., Hermann, D.M., LDL attenuates VEGF-induced angiogenesis via mechanisms involving VEGFR2 internalization and degradation following endosome-trans-Golgi network trafficking. Angiogenesis, 16, 2013, 625–637.
    • (2013) Angiogenesis , vol.16 , pp. 625-637
    • Jin, F.1    Hagemann, N.2    Brockmeier, U.3    Schafer, S.T.4    Zechariah, A.5    Hermann, D.M.6
  • 237
    • 84879082098 scopus 로고    scopus 로고
    • Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells
    • [237] Zechariah, A., ElAli, A., Hagemann, N., Jin, F., Doeppner, T.R., Helfrich, I., Mies, G., Hermann, D.M., Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells. Arterioscler Thromb. Vasc. Biol. 33:7 (2013), 1561–1567.
    • (2013) Arterioscler Thromb. Vasc. Biol. , vol.33 , Issue.7 , pp. 1561-1567
    • Zechariah, A.1    ElAli, A.2    Hagemann, N.3    Jin, F.4    Doeppner, T.R.5    Helfrich, I.6    Mies, G.7    Hermann, D.M.8
  • 238
    • 84866599179 scopus 로고    scopus 로고
    • Moderate to high concentrations of high-density lipoprotein from healthy subjects paradoxically impair human endothelial progenitor cells and related angiogenesis by activating Rho-associated kinase pathways
    • [238] Huang, C.Y., Lin, F.Y., Shih, C.M., Au, H.K., Chang, Y.J., Nakagami, H., Morishita, R., Chang, N.C., Shyu, K.G., Chen, J.W., Moderate to high concentrations of high-density lipoprotein from healthy subjects paradoxically impair human endothelial progenitor cells and related angiogenesis by activating Rho-associated kinase pathways. Arterioscler Thromb. Vasc. Biol. 32:10 (2012), 2405–2417.
    • (2012) Arterioscler Thromb. Vasc. Biol. , vol.32 , Issue.10 , pp. 2405-2417
    • Huang, C.Y.1    Lin, F.Y.2    Shih, C.M.3    Au, H.K.4    Chang, Y.J.5    Nakagami, H.6    Morishita, R.7    Chang, N.C.8    Shyu, K.G.9    Chen, J.W.10
  • 239
    • 84923046255 scopus 로고    scopus 로고
    • Cholesterol, inflammation and innate immunity
    • [239] Tall, A.R., Yvan-Charvet, L., Cholesterol, inflammation and innate immunity. Nat. Rev. Immunol. 15:2 (2015), 104–116.
    • (2015) Nat. Rev. Immunol. , vol.15 , Issue.2 , pp. 104-116
    • Tall, A.R.1    Yvan-Charvet, L.2
  • 240
    • 36049027675 scopus 로고    scopus 로고
    • Small concentrations of oxLDL induce capillary tube formation from endothelial cells via LOX-1-dependent redox-sensitive pathway
    • [240] Dandapat, A., Hu, C., Sun, L., Mehta, J.L., Small concentrations of oxLDL induce capillary tube formation from endothelial cells via LOX-1-dependent redox-sensitive pathway. Arterioscler Thromb. Vasc. Biol. 27:11 (2007), 2435–2442.
    • (2007) Arterioscler Thromb. Vasc. Biol. , vol.27 , Issue.11 , pp. 2435-2442
    • Dandapat, A.1    Hu, C.2    Sun, L.3    Mehta, J.L.4
  • 241
    • 79953162175 scopus 로고    scopus 로고
    • Oxidized LDL at low concentration promotes in-vitro angiogenesis and activates nitric oxide synthase through PI3K/Akt/eNOS pathway in human coronary artery endothelial cells
    • [241] Yu, S., Wong, S.L., Lau, C.W., Huang, Y., Yu, C.M., Oxidized LDL at low concentration promotes in-vitro angiogenesis and activates nitric oxide synthase through PI3K/Akt/eNOS pathway in human coronary artery endothelial cells. Biochem Biophys. Res Commun. 407:1 (2011), 44–48.
    • (2011) Biochem Biophys. Res Commun. , vol.407 , Issue.1 , pp. 44-48
    • Yu, S.1    Wong, S.L.2    Lau, C.W.3    Huang, Y.4    Yu, C.M.5
  • 242
    • 84868095936 scopus 로고    scopus 로고
    • Large impact of low concentration oxidized LDL on angiogenic potential of human endothelial cells: a microarray study
    • [242] Khaidakov, M., Mitra, S., Wang, X., Ding, Z., Bora, N., Lyzogubov, V., Romeo, F., Schichman, S.A., Mehta, J.L., Large impact of low concentration oxidized LDL on angiogenic potential of human endothelial cells: a microarray study. PLoS One, 7(10), 2012, e47421.
    • (2012) PLoS One , vol.7 , Issue.10 , pp. e47421
    • Khaidakov, M.1    Mitra, S.2    Wang, X.3    Ding, Z.4    Bora, N.5    Lyzogubov, V.6    Romeo, F.7    Schichman, S.A.8    Mehta, J.L.9
  • 245
    • 84880512414 scopus 로고    scopus 로고
    • Macrophages transmit potent proangiogenic effects of oxLDL in vitro and in vivo involving HIF-1alpha activation: a novel aspect of angiogenesis in atherosclerosis
    • [245] Hutter, R., Speidl, W.S., Valdiviezo, C., Sauter, B., Corti, R., Fuster, V., Badimon, J.J., Macrophages transmit potent proangiogenic effects of oxLDL in vitro and in vivo involving HIF-1alpha activation: a novel aspect of angiogenesis in atherosclerosis. J. Cardiovasc Transl. Res. 6:4 (2013), 558–569.
    • (2013) J. Cardiovasc Transl. Res. , vol.6 , Issue.4 , pp. 558-569
    • Hutter, R.1    Speidl, W.S.2    Valdiviezo, C.3    Sauter, B.4    Corti, R.5    Fuster, V.6    Badimon, J.J.7
  • 246
    • 0038115172 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1alpha (HIF-1alpha) accumulation via redox-dependent mechanisms
    • [246] Shatrov, V.A., Sumbayev, V.V., Zhou, J., Brune, B., Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1alpha (HIF-1alpha) accumulation via redox-dependent mechanisms. Blood 101:12 (2003), 4847–4849.
    • (2003) Blood , vol.101 , Issue.12 , pp. 4847-4849
    • Shatrov, V.A.1    Sumbayev, V.V.2    Zhou, J.3    Brune, B.4
  • 248
    • 33847063862 scopus 로고    scopus 로고
    • Hydrogen peroxide induces S1P1 receptors and sensitizes vascular endothelial cells to sphingosine 1-phosphate, a platelet-derived lipid mediator
    • [248] Igarashi, J., Miyoshi, M., Hashimoto, T., Kubota, Y., Kosaka, H., Hydrogen peroxide induces S1P1 receptors and sensitizes vascular endothelial cells to sphingosine 1-phosphate, a platelet-derived lipid mediator. Am. J. Physiol. Cell Physiol. 292:2 (2007), C740–C748.
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292 , Issue.2 , pp. C740-C748
    • Igarashi, J.1    Miyoshi, M.2    Hashimoto, T.3    Kubota, Y.4    Kosaka, H.5
  • 250
    • 0027459263 scopus 로고
    • Oxidized low density lipoprotein inhibits the migration of aortic endothelial cells in vitro
    • [250] Murugesan, G., Chisolm, G.M., Fox, P.L., Oxidized low density lipoprotein inhibits the migration of aortic endothelial cells in vitro. J. Cell Biol. 120:4 (1993), 1011–1019.
    • (1993) J. Cell Biol. , vol.120 , Issue.4 , pp. 1011-1019
    • Murugesan, G.1    Chisolm, G.M.2    Fox, P.L.3
  • 251
    • 0033963466 scopus 로고    scopus 로고
    • Oxidized low-density lipoproteins inhibit endothelial cell proliferation by suppressing basic fibroblast growth factor expression
    • [251] Chen, C.H., Jiang, W., Via, D.P., Luo, S., Li, T.R., Lee, Y.T., Henry, P.D., Oxidized low-density lipoproteins inhibit endothelial cell proliferation by suppressing basic fibroblast growth factor expression. Circulation 101:2 (2000), 171–177.
    • (2000) Circulation , vol.101 , Issue.2 , pp. 171-177
    • Chen, C.H.1    Jiang, W.2    Via, D.P.3    Luo, S.4    Li, T.R.5    Lee, Y.T.6    Henry, P.D.7
  • 252
    • 84873683297 scopus 로고    scopus 로고
    • 7-Ketocholesterol induces inflammation and angiogenesis in vivo: a novel rat model
    • [252] Amaral, J., Lee, J.W., Chou, J., Campos, M.M., Rodriguez, I.R., 7-Ketocholesterol induces inflammation and angiogenesis in vivo: a novel rat model. PLoS One, 8(2), 2013, e56099.
    • (2013) PLoS One , vol.8 , Issue.2 , pp. e56099
    • Amaral, J.1    Lee, J.W.2    Chou, J.3    Campos, M.M.4    Rodriguez, I.R.5
  • 254
    • 37849013375 scopus 로고    scopus 로고
    • Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors
    • [254] Negre-Salvayre, A., Coatrieux, C., Ingueneau, C., Salvayre, R., Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors. Br. J. Pharm. 153:1 (2008), 6–20.
    • (2008) Br. J. Pharm. , vol.153 , Issue.1 , pp. 6-20
    • Negre-Salvayre, A.1    Coatrieux, C.2    Ingueneau, C.3    Salvayre, R.4
  • 255
    • 84929084701 scopus 로고    scopus 로고
    • The pharmacology of the cytochrome P450 epoxygenase/soluble epoxide hydrolase axis in the vasculature and cardiovascular disease
    • [255] Fleming, I., The pharmacology of the cytochrome P450 epoxygenase/soluble epoxide hydrolase axis in the vasculature and cardiovascular disease. Pharm. Rev. 66:4 (2014), 1106–1140.
    • (2014) Pharm. Rev. , vol.66 , Issue.4 , pp. 1106-1140
    • Fleming, I.1
  • 256
    • 17944387960 scopus 로고    scopus 로고
    • Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo
    • [256] Watson, A.D., Leitinger, N., Navab, M., Faull, K.F., Horkko, S., Witztum, J.L., Palinski, W., Schwenke, D., Salomon, R.G., Sha, W., Subbanagounder, G., Fogelman, A.M., Berliner, J.A., Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo. J. Biol. Chem. 272:21 (1997), 13597–13607.
    • (1997) J. Biol. Chem. , vol.272 , Issue.21 , pp. 13597-13607
    • Watson, A.D.1    Leitinger, N.2    Navab, M.3    Faull, K.F.4    Horkko, S.5    Witztum, J.L.6    Palinski, W.7    Schwenke, D.8    Salomon, R.G.9    Sha, W.10    Subbanagounder, G.11    Fogelman, A.M.12    Berliner, J.A.13
  • 257
    • 0034659147 scopus 로고    scopus 로고
    • Role of reactive aldehyde in cardiovascular diseases
    • [257] Uchida, K., Role of reactive aldehyde in cardiovascular diseases. Free Radic. Biol. Med. 28:12 (2000), 1685–1696.
    • (2000) Free Radic. Biol. Med. , vol.28 , Issue.12 , pp. 1685-1696
    • Uchida, K.1
  • 260
    • 20144374665 scopus 로고    scopus 로고
    • High-density lipoproteins prevent the oxidized low-density lipoprotein-induced epidermal [corrected] growth factor receptor activation and subsequent matrix metalloproteinase-2 upregulation
    • [260] Robbesyn, F., Auge, N., Vindis, C., Cantero, A.V., Barbaras, R., Negre-Salvayre, A., Salvayre, R., High-density lipoproteins prevent the oxidized low-density lipoprotein-induced epidermal [corrected] growth factor receptor activation and subsequent matrix metalloproteinase-2 upregulation. Arterioscler Thromb. Vasc. Biol. 25:6 (2005), 1206–1212.
    • (2005) Arterioscler Thromb. Vasc. Biol. , vol.25 , Issue.6 , pp. 1206-1212
    • Robbesyn, F.1    Auge, N.2    Vindis, C.3    Cantero, A.V.4    Barbaras, R.5    Negre-Salvayre, A.6    Salvayre, R.7
  • 261
    • 0041669506 scopus 로고    scopus 로고
    • Oxidized LDL and 4-hydroxynonenal modulate tyrosine kinase receptor activity
    • [261] Negre-Salvayre, A., Vieira, O., Escargueil-Blanc, I., Salvayre, R., Oxidized LDL and 4-hydroxynonenal modulate tyrosine kinase receptor activity. Mol. Asp. Med. 24:4–5 (2003), 251–261.
    • (2003) Mol. Asp. Med. , vol.24 , Issue.4-5 , pp. 251-261
    • Negre-Salvayre, A.1    Vieira, O.2    Escargueil-Blanc, I.3    Salvayre, R.4
  • 262
    • 17144448343 scopus 로고    scopus 로고
    • Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells
    • [262] Robino, G., Parola, M., Marra, F., Caligiuri, A., De Franco, R.M., Zamara, E., Bellomo, G., Gentilini, P., Pinzani, M., Dianzani, M.U., Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells. J. Biol. Chem. 275:51 (2000), 40561–40567.
    • (2000) J. Biol. Chem. , vol.275 , Issue.51 , pp. 40561-40567
    • Robino, G.1    Parola, M.2    Marra, F.3    Caligiuri, A.4    De Franco, R.M.5    Zamara, E.6    Bellomo, G.7    Gentilini, P.8    Pinzani, M.9    Dianzani, M.U.10
  • 263
    • 33645741763 scopus 로고    scopus 로고
    • Desensitization of platelet-derived growth factor receptor-beta by oxidized lipids in vascular cells and atherosclerotic lesions: prevention by aldehyde scavengers
    • [263] Vindis, C., Escargueil-Blanc, I., Elbaz, M., Marcheix, B., Grazide, M.H., Uchida, K., Salvayre, R., Negre-Salvayre, A., Desensitization of platelet-derived growth factor receptor-beta by oxidized lipids in vascular cells and atherosclerotic lesions: prevention by aldehyde scavengers. Circ. Res. 98:6 (2006), 785–792.
    • (2006) Circ. Res. , vol.98 , Issue.6 , pp. 785-792
    • Vindis, C.1    Escargueil-Blanc, I.2    Elbaz, M.3    Marcheix, B.4    Grazide, M.H.5    Uchida, K.6    Salvayre, R.7    Negre-Salvayre, A.8
  • 264
    • 77956246887 scopus 로고    scopus 로고
    • Cigarette smoke-mediated oxidative stress, shear stress, and endothelial dysfunction: role of VEGFR2
    • [264] Edirisinghe, I., Rahman, I., Cigarette smoke-mediated oxidative stress, shear stress, and endothelial dysfunction: role of VEGFR2. Ann. NY Acad. Sci. 1203 (2010), 66–72.
    • (2010) Ann. NY Acad. Sci. , vol.1203 , pp. 66-72
    • Edirisinghe, I.1    Rahman, I.2
  • 265
    • 84895076295 scopus 로고    scopus 로고
    • Zebrafish models of dyslipidemia: relevance to atherosclerosis and angiogenesis
    • [265] Fang, L., Liu, C., Miller, Y.I., Zebrafish models of dyslipidemia: relevance to atherosclerosis and angiogenesis. Transl. Res. 163:2 (2014), 99–108.
    • (2014) Transl. Res. , vol.163 , Issue.2 , pp. 99-108
    • Fang, L.1    Liu, C.2    Miller, Y.I.3
  • 266
    • 84881029676 scopus 로고    scopus 로고
    • Endothelial lipase is a critical determinant of high-density lipoprotein-stimulated sphingosine 1-phosphate-dependent signaling in vascular endothelium
    • [266] Tatematsu, S., Francis, S.A., Natarajan, P., Rader, D.J., Saghatelian, A., Brown, J.D., Michel, T., Plutzky, J., Endothelial lipase is a critical determinant of high-density lipoprotein-stimulated sphingosine 1-phosphate-dependent signaling in vascular endothelium. Arterioscler Thromb. Vasc. Biol. 33:8 (2013), 1788–1794.
    • (2013) Arterioscler Thromb. Vasc. Biol. , vol.33 , Issue.8 , pp. 1788-1794
    • Tatematsu, S.1    Francis, S.A.2    Natarajan, P.3    Rader, D.J.4    Saghatelian, A.5    Brown, J.D.6    Michel, T.7    Plutzky, J.8
  • 267
    • 85012266151 scopus 로고    scopus 로고
    • Molecule at the Interface of Cholesterol Transport, Angiogenesis, and Atherosclerosis
    • [267] Zhu, L., Fang, L., AIBP, Novel, A., Molecule at the Interface of Cholesterol Transport, Angiogenesis, and Atherosclerosis. Methodist Debakey Cardiovasc. J. 11:3 (2015), 160–165.
    • (2015) Methodist Debakey Cardiovasc. J. , vol.11 , Issue.3 , pp. 160-165
    • Zhu, L.1    Fang, L.2    AIBP3    Novel, A.4
  • 269
    • 80055022338 scopus 로고    scopus 로고
    • Early atheroma-derived agonists of peroxisome proliferator-activated receptor-gamma trigger intramedial angiogenesis in a smooth muscle cell-dependent manner
    • [269] Ho-Tin-Noe, B., Le Dall, J., Gomez, D., Louedec, L., Vranckx, R., El-Bouchtaoui, M., Legres, L., Meilhac, O., Michel, J.B., Early atheroma-derived agonists of peroxisome proliferator-activated receptor-gamma trigger intramedial angiogenesis in a smooth muscle cell-dependent manner. Circ. Res. 109:9 (2011), 1003–1014.
    • (2011) Circ. Res. , vol.109 , Issue.9 , pp. 1003-1014
    • Ho-Tin-Noe, B.1    Le Dall, J.2    Gomez, D.3    Louedec, L.4    Vranckx, R.5    El-Bouchtaoui, M.6    Legres, L.7    Meilhac, O.8    Michel, J.B.9
  • 271
    • 60749137151 scopus 로고    scopus 로고
    • NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology
    • [271] Frey, R.S., Ushio-Fukai, M., Malik, A.B., NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology. Antioxid. Redox Signal 11:4 (2009), 791–810.
    • (2009) Antioxid. Redox Signal , vol.11 , Issue.4 , pp. 791-810
    • Frey, R.S.1    Ushio-Fukai, M.2    Malik, A.B.3
  • 272
    • 84927647026 scopus 로고    scopus 로고
    • Regulation of signal transduction by reactive oxygen species in the cardiovascular system
    • [272] Brown, D.I., Griendling, K.K., Regulation of signal transduction by reactive oxygen species in the cardiovascular system. Circ. Res. 116:3 (2015), 531–549.
    • (2015) Circ. Res. , vol.116 , Issue.3 , pp. 531-549
    • Brown, D.I.1    Griendling, K.K.2
  • 273
    • 84952939010 scopus 로고    scopus 로고
    • Oxidative theory of atherosclerosis and antioxidants
    • [273] Salvayre, R., Negre-Salvayre, A., Camare, C., Oxidative theory of atherosclerosis and antioxidants. Biochimie 125 (2016), 281–296.
    • (2016) Biochimie , vol.125 , pp. 281-296
    • Salvayre, R.1    Negre-Salvayre, A.2    Camare, C.3
  • 274
    • 0030917699 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor in balloon-injured baboon arteries. A novel role for reactive oxygen species in atherosclerosis
    • [274] Ruef, J., Hu, Z.Y., Yin, L.Y., Wu, Y., Hanson, S.R., Kelly, A.B., Harker, L.A., Rao, G.N., Runge, M.S., Patterson, C., Induction of vascular endothelial growth factor in balloon-injured baboon arteries. A novel role for reactive oxygen species in atherosclerosis. Circ. Res. 81:1 (1997), 24–33.
    • (1997) Circ. Res. , vol.81 , Issue.1 , pp. 24-33
    • Ruef, J.1    Hu, Z.Y.2    Yin, L.Y.3    Wu, Y.4    Hanson, S.R.5    Kelly, A.B.6    Harker, L.A.7    Rao, G.N.8    Runge, M.S.9    Patterson, C.10
  • 276
    • 84896958332 scopus 로고    scopus 로고
    • Oxidative stress in angiogenesis and vascular disease
    • [276] Kim, Y.W., Byzova, T.V., Oxidative stress in angiogenesis and vascular disease. Blood 123:5 (2014), 625–631.
    • (2014) Blood , vol.123 , Issue.5 , pp. 625-631
    • Kim, Y.W.1    Byzova, T.V.2
  • 277
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • [277] Ross, R., Atherosclerosis-an inflammatory disease. N. Engl. J. Med. 340:2 (1999), 115–126.
    • (1999) N. Engl. J. Med. , vol.340 , Issue.2 , pp. 115-126
    • Ross, R.1
  • 278
    • 37249010527 scopus 로고    scopus 로고
    • Involvement of intraplaque hemorrhage in atherothrombosis evolution via neutrophil protease enrichment
    • [278] Leclercq, A., Houard, X., Philippe, M., Ollivier, V., Sebbag, U., Meilhac, O., Michel, J.B., Involvement of intraplaque hemorrhage in atherothrombosis evolution via neutrophil protease enrichment. J. Leukoc. Biol. 82:6 (2007), 1420–1429.
    • (2007) J. Leukoc. Biol. , vol.82 , Issue.6 , pp. 1420-1429
    • Leclercq, A.1    Houard, X.2    Philippe, M.3    Ollivier, V.4    Sebbag, U.5    Meilhac, O.6    Michel, J.B.7
  • 279
    • 77951686244 scopus 로고    scopus 로고
    • Extracellular matrix, inflammation, and the angiogenic response
    • [279] Arroyo, A.G., Iruela-Arispe, M.L., Extracellular matrix, inflammation, and the angiogenic response. Cardiovasc. Res. 86:2 (2010), 226–235.
    • (2010) Cardiovasc. Res. , vol.86 , Issue.2 , pp. 226-235
    • Arroyo, A.G.1    Iruela-Arispe, M.L.2
  • 280
    • 79956319051 scopus 로고    scopus 로고
    • Progress and challenges in translating the biology of atherosclerosis
    • [280] Libby, P., Ridker, P.M., Hansson, G.K., Progress and challenges in translating the biology of atherosclerosis. Nature 473:7347 (2011), 317–325.
    • (2011) Nature , vol.473 , Issue.7347 , pp. 317-325
    • Libby, P.1    Ridker, P.M.2    Hansson, G.K.3
  • 281
    • 77956187467 scopus 로고    scopus 로고
    • Signaling by members of the TGF-beta family in vascular morphogenesis and disease
    • [281] Pardali, E., Goumans, M.J., ten Dijke, P., Signaling by members of the TGF-beta family in vascular morphogenesis and disease. Trends Cell Biol. 20:9 (2010), 556–567.
    • (2010) Trends Cell Biol. , vol.20 , Issue.9 , pp. 556-567
    • Pardali, E.1    Goumans, M.J.2    ten Dijke, P.3
  • 282
    • 42949175181 scopus 로고    scopus 로고
    • Matrix metalloproteinase control of capillary morphogenesis
    • [282] Ghajar, C.M., George, S.C., Putnam, A.J., Matrix metalloproteinase control of capillary morphogenesis. Crit. Rev. Eukaryot. Gene Expr. 18:3 (2008), 251–278.
    • (2008) Crit. Rev. Eukaryot. Gene Expr. , vol.18 , Issue.3 , pp. 251-278
    • Ghajar, C.M.1    George, S.C.2    Putnam, A.J.3
  • 284
    • 28444488632 scopus 로고    scopus 로고
    • Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model
    • [284] Karagiannis, E.D., Popel, A.S., Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model. J. Theor. Biol. 238:1 (2006), 124–145.
    • (2006) J. Theor. Biol. , vol.238 , Issue.1 , pp. 124-145
    • Karagiannis, E.D.1    Popel, A.S.2
  • 285
    • 3543141882 scopus 로고    scopus 로고
    • Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation
    • [285] Auge, N., Maupas-Schwalm, F., Elbaz, M., Thiers, J.C., Waysbort, A., Itohara, S., Krell, H.W., Salvayre, R., Negre-Salvayre, A., Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation. Circulation 110:5 (2004), 571–578.
    • (2004) Circulation , vol.110 , Issue.5 , pp. 571-578
    • Auge, N.1    Maupas-Schwalm, F.2    Elbaz, M.3    Thiers, J.C.4    Waysbort, A.5    Itohara, S.6    Krell, H.W.7    Salvayre, R.8    Negre-Salvayre, A.9
  • 286
    • 1842474897 scopus 로고    scopus 로고
    • Membrane type 1-matrix metalloproteinase (MT1-MMP) cooperates with sphingosine 1-phosphate to induce endothelial cell migration and morphogenic differentiation
    • [286] Langlois, S., Gingras, D., Beliveau, R., Membrane type 1-matrix metalloproteinase (MT1-MMP) cooperates with sphingosine 1-phosphate to induce endothelial cell migration and morphogenic differentiation. Blood 103:8 (2004), 3020–3028.
    • (2004) Blood , vol.103 , Issue.8 , pp. 3020-3028
    • Langlois, S.1    Gingras, D.2    Beliveau, R.3
  • 287
    • 0038045489 scopus 로고    scopus 로고
    • Matrix metalloproteinase regulation of sphingosine-1-phosphate-induced angiogenic properties of bone marrow stromal cells
    • [287] Annabi, B., Thibeault, S., Lee, Y.T., Bousquet-Gagnon, N., Eliopoulos, N., Barrette, S., Galipeau, J., Beliveau, R., Matrix metalloproteinase regulation of sphingosine-1-phosphate-induced angiogenic properties of bone marrow stromal cells. Exp. Hematol. 31:7 (2003), 640–649.
    • (2003) Exp. Hematol. , vol.31 , Issue.7 , pp. 640-649
    • Annabi, B.1    Thibeault, S.2    Lee, Y.T.3    Bousquet-Gagnon, N.4    Eliopoulos, N.5    Barrette, S.6    Galipeau, J.7    Beliveau, R.8
  • 288
    • 34249869816 scopus 로고    scopus 로고
    • Different networks, common growth factors: shared growth factors and receptors of the vascular and the nervous system
    • [288] Raab, S., Plate, K.H., Different networks, common growth factors: shared growth factors and receptors of the vascular and the nervous system. Acta Neuropathol. 113:6 (2007), 607–626.
    • (2007) Acta Neuropathol. , vol.113 , Issue.6 , pp. 607-626
    • Raab, S.1    Plate, K.H.2
  • 290
    • 80155183449 scopus 로고    scopus 로고
    • Tension in the plaque: hypoxia modulates metabolism in atheroma
    • [290] Libby, P., Folco, E., Tension in the plaque: hypoxia modulates metabolism in atheroma. Circ. Res. 109:10 (2011), 1100–1102.
    • (2011) Circ. Res. , vol.109 , Issue.10 , pp. 1100-1102
    • Libby, P.1    Folco, E.2
  • 291
    • 80052009179 scopus 로고    scopus 로고
    • Intraplaque haemorrhages as the trigger of plaque vulnerability
    • (1985a, 1985b, 1985c)
    • [291] Michel, J.B., Virmani, R., Arbustini, E., Pasterkamp, G., Intraplaque haemorrhages as the trigger of plaque vulnerability. Eur. Heart J. 32:16 (2011), 1977–1985 (1985a, 1985b, 1985c).
    • (2011) Eur. Heart J. , vol.32 , Issue.16 , pp. 1977-1985
    • Michel, J.B.1    Virmani, R.2    Arbustini, E.3    Pasterkamp, G.4
  • 292
    • 25444522479 scopus 로고    scopus 로고
    • Role of angiogenesis in cardiovascular disease: a critical appraisal
    • [292] Khurana, R., Simons, M., Martin, J.F., Zachary, I.C., Role of angiogenesis in cardiovascular disease: a critical appraisal. Circulation 112:12 (2005), 1813–1824.
    • (2005) Circulation , vol.112 , Issue.12 , pp. 1813-1824
    • Khurana, R.1    Simons, M.2    Martin, J.F.3    Zachary, I.C.4
  • 293
    • 0032865511 scopus 로고    scopus 로고
    • Angiogenesis and the atherosclerotic carotid plaque: an association between symptomatology and plaque morphology
    • [293] McCarthy, M.J., Loftus, I.M., Thompson, M.M., Jones, L., London, N.J., Bell, P.R., Naylor, A.R., Brindle, N.P., Angiogenesis and the atherosclerotic carotid plaque: an association between symptomatology and plaque morphology. J. Vasc. Surg. 30:2 (1999), 261–268.
    • (1999) J. Vasc. Surg. , vol.30 , Issue.2 , pp. 261-268
    • McCarthy, M.J.1    Loftus, I.M.2    Thompson, M.M.3    Jones, L.4    London, N.J.5    Bell, P.R.6    Naylor, A.R.7    Brindle, N.P.8
  • 294
    • 34548285848 scopus 로고    scopus 로고
    • Correlation between carotid intraplaque hemorrhage and clinical symptoms: systematic review of observational studies
    • [294] Gao, P., Chen, Z.Q., Bao, Y.H., Jiao, L.Q., Ling, F., Correlation between carotid intraplaque hemorrhage and clinical symptoms: systematic review of observational studies. Stroke 38:8 (2007), 2382–2390.
    • (2007) Stroke , vol.38 , Issue.8 , pp. 2382-2390
    • Gao, P.1    Chen, Z.Q.2    Bao, Y.H.3    Jiao, L.Q.4    Ling, F.5
  • 296
    • 62849117145 scopus 로고    scopus 로고
    • Effect of cholesterol crystals on plaques and intima in arteries of patients with acute coronary and cerebrovascular syndromes
    • [296] Abela, G.S., Aziz, K., Vedre, A., Pathak, D.R., Talbott, J.D., Dejong, J., Effect of cholesterol crystals on plaques and intima in arteries of patients with acute coronary and cerebrovascular syndromes. Am. J. Cardiol. 103:7 (2009), 959–968.
    • (2009) Am. J. Cardiol. , vol.103 , Issue.7 , pp. 959-968
    • Abela, G.S.1    Aziz, K.2    Vedre, A.3    Pathak, D.R.4    Talbott, J.D.5    Dejong, J.6
  • 298
    • 77955356552 scopus 로고    scopus 로고
    • Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation
    • [298] Rajamaki, K., Lappalainen, J., Oorni, K., Valimaki, E., Matikainen, S., Kovanen, P.T., Eklund, K.K., Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation. PLoS One, 5(7), 2010, e11765.
    • (2010) PLoS One , vol.5 , Issue.7 , pp. e11765
    • Rajamaki, K.1    Lappalainen, J.2    Oorni, K.3    Valimaki, E.4    Matikainen, S.5    Kovanen, P.T.6    Eklund, K.K.7
  • 299
    • 34248646760 scopus 로고    scopus 로고
    • Total cholesterol content of erythrocyte membranes is increased in patients with acute coronary syndrome: a new marker of clinical instability?
    • [299] Tziakas, D.N., Kaski, J.C., Chalikias, G.K., Romero, C., Fredericks, S., Tentes, I.K., Kortsaris, A.X., Hatseras, D.I., Holt, D.W., Total cholesterol content of erythrocyte membranes is increased in patients with acute coronary syndrome: a new marker of clinical instability?. J. Am. Coll. Cardiol. 49:21 (2007), 2081–2089.
    • (2007) J. Am. Coll. Cardiol. , vol.49 , Issue.21 , pp. 2081-2089
    • Tziakas, D.N.1    Kaski, J.C.2    Chalikias, G.K.3    Romero, C.4    Fredericks, S.5    Tentes, I.K.6    Kortsaris, A.X.7    Hatseras, D.I.8    Holt, D.W.9
  • 301
    • 0024603895 scopus 로고
    • Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
    • [301] Steinberg, D., Parthasarathy, S., Carew, T.E., Khoo, J.C., Witztum, J.L., Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320:14 (1989), 915–924.
    • (1989) N. Engl. J. Med. , vol.320 , Issue.14 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 302
    • 0025282662 scopus 로고
    • Biochemical, structural, and functional properties of oxidized low-density lipoprotein
    • [302] Esterbauer, H., Dieber-Rotheneder, M., Waeg, G., Striegl, G., Jurgens, G., Biochemical, structural, and functional properties of oxidized low-density lipoprotein. Chem. Res. Toxicol. 3:2 (1990), 77–92.
    • (1990) Chem. Res. Toxicol. , vol.3 , Issue.2 , pp. 77-92
    • Esterbauer, H.1    Dieber-Rotheneder, M.2    Waeg, G.3    Striegl, G.4    Jurgens, G.5
  • 303
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • [303] Stocker, R., Keaney, J.F. Jr., Role of oxidative modifications in atherosclerosis. Physiol. Rev. 84:4 (2004), 1381–1478.
    • (2004) Physiol. Rev. , vol.84 , Issue.4 , pp. 1381-1478
    • Stocker, R.1    Keaney, J.F.2
  • 307
    • 34347346141 scopus 로고    scopus 로고
    • The phosphatidylserine receptor mediates phagocytosis by vascular smooth muscle cells
    • [307] Kolb, S., Vranckx, R., Huisse, M.G., Michel, J.B., Meilhac, O., The phosphatidylserine receptor mediates phagocytosis by vascular smooth muscle cells. J. Pathol. 212:3 (2007), 249–259.
    • (2007) J. Pathol. , vol.212 , Issue.3 , pp. 249-259
    • Kolb, S.1    Vranckx, R.2    Huisse, M.G.3    Michel, J.B.4    Meilhac, O.5
  • 308
    • 77049116995 scopus 로고    scopus 로고
    • The haptoglobin 2-2 genotype is associated with increased redox active hemoglobin derived iron in the atherosclerotic plaque
    • [308] Kalet-Litman, S., Moreno, P.R., Levy, A.P., The haptoglobin 2-2 genotype is associated with increased redox active hemoglobin derived iron in the atherosclerotic plaque. Atherosclerosis 209:1 (2010), 28–31.
    • (2010) Atherosclerosis , vol.209 , Issue.1 , pp. 28-31
    • Kalet-Litman, S.1    Moreno, P.R.2    Levy, A.P.3
  • 310
    • 0035108136 scopus 로고    scopus 로고
    • Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes
    • [310] Sugiyama, S., Okada, Y., Sukhova, G.K., Virmani, R., Heinecke, J.W., Libby, P., Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am. J. Pathol. 158:3 (2001), 879–891.
    • (2001) Am. J. Pathol. , vol.158 , Issue.3 , pp. 879-891
    • Sugiyama, S.1    Okada, Y.2    Sukhova, G.K.3    Virmani, R.4    Heinecke, J.W.5    Libby, P.6
  • 311
    • 73449143528 scopus 로고    scopus 로고
    • Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease
    • [311] van der Veen, B.S., de Winther, M.P., Heeringa, P., Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease. Antioxid. Redox Signal 11:11 (2009), 2899–2937.
    • (2009) Antioxid. Redox Signal , vol.11 , Issue.11 , pp. 2899-2937
    • van der Veen, B.S.1    de Winther, M.P.2    Heeringa, P.3
  • 317
    • 13044300888 scopus 로고    scopus 로고
    • Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2
    • [317] Griffith, E.C., Su, Z., Niwayama, S., Ramsay, C.A., Chang, Y.H., Liu, J.O., Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2. Proc. Natl. Acad. Sci. USA 95:26 (1998), 15183–15188.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.26 , pp. 15183-15188
    • Griffith, E.C.1    Su, Z.2    Niwayama, S.3    Ramsay, C.A.4    Chang, Y.H.5    Liu, J.O.6
  • 320
    • 0037192331 scopus 로고    scopus 로고
    • Simvastatin preserves the structure of coronary adventitial vasa vasorum in experimental hypercholesterolemia independent of lipid lowering
    • [320] Wilson, S.H., Herrmann, J., Lerman, L.O., Holmes, D.R. Jr., Napoli, C., Ritman, E.L., Lerman, A., Simvastatin preserves the structure of coronary adventitial vasa vasorum in experimental hypercholesterolemia independent of lipid lowering. Circulation 105:4 (2002), 415–418.
    • (2002) Circulation , vol.105 , Issue.4 , pp. 415-418
    • Wilson, S.H.1    Herrmann, J.2    Lerman, L.O.3    Holmes, D.R.4    Napoli, C.5    Ritman, E.L.6    Lerman, A.7
  • 321
    • 84945905517 scopus 로고    scopus 로고
    • Intravitreal Antivascular Endothelial Growth Factor Therapy May Induce Proteinuria and Antibody Mediated Injury in Renal Allografts
    • [321] Cheungpasitporn, W., Chebib, F.T., Cornell, L.D., Brodin, M.L., Nasr, S.H., Schinstock, C.A., Stegall, M.D., Amer, H., Intravitreal Antivascular Endothelial Growth Factor Therapy May Induce Proteinuria and Antibody Mediated Injury in Renal Allografts. Transplantation 99:11 (2015), 2382–2386.
    • (2015) Transplantation , vol.99 , Issue.11 , pp. 2382-2386
    • Cheungpasitporn, W.1    Chebib, F.T.2    Cornell, L.D.3    Brodin, M.L.4    Nasr, S.H.5    Schinstock, C.A.6    Stegall, M.D.7    Amer, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.