Control of angiogenesis by AIBP-mediated cholesterol efflux

Nature

Volumn 498, Issue 7452, 2013, Pages 118-122

  Fang, Longhou ^a   Choi, Soo Ho ^a   Baek, Ji Sun ^a   Liu, Chao ^a   Almazan, Felicidad ^a   Ulrich, Florian ^b   Wiesner, Philipp ^a   Taleb, Adam ^a   Deer, Elena ^a   Pattison, Jennifer ^a   Torres Vázquez, Jesús ^b   Li, Andrew C ^a   Miller, Yury I ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER G1; APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN; PLEXIN; VASCULOTROPIN RECEPTOR 2;

DISEASE; LIPID; MEMBRANE; PROTEIN; SIGNALING;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CHOLESTEROL TRANSPORT; DIMERIZATION; ENDOCYTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; BLOOD VESSELS; CARRIER PROTEINS; CHOLESTEROL; EMBRYO, NONMAMMALIAN; ENDOTHELIAL CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIPOPROTEINS, HDL; MEMBRANE LIPIDS; MEMBRANE MICRODOMAINS; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 84878682318     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12166     Document Type: Article

References (42)

1. Bodzioch, M. et al. The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nature Genet. 22, 347-351 (1999).
2. Rust, S. et al. Tangier disease is caused by mutations in the gene encoding ATPbinding cassette transporter 1. Nature Genet. 22, 352-355 (1999).
3. Klucken, J. et al. ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport. Proc. Natl Acad. Sci. USA 97, 817-822 (2000).
4. Yvan-Charvet, L. et al. ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. Science 328, 1689-1693 (2010).
5. Armstrong, A. J., Gebre, A. K., Parks, J. S. & Hedrick, C. C. ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation. J. Immunol. 184, 173-183 (2010).
6. Bensinger,S. J. et al.LXRsignaling couples sterolmetabolismto proliferation in the acquired immune response. Cell 134, 97-111 (2008).
7. Ritter, M. et al. Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response toHDL or apoA-I. Genomics 79, 693-702 (2002).
8. Jha, K. N. et al. Biochemical and structural characterization of apolipoprotein A-I binding protein, a novel phosphoprotein with a potential role in sperm capacitation. Endocrinology 149, 2108-2120 (2008).
9. Stefulj, J. et al. Human endothelial cells of the placental barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1. Circ. Res. 104, 600-608 (2009).
10. Terasaka, N. et al.ABCG1 andHDL protect against endothelial dysfunction in mice fed a high-cholesterol diet. J. Clin. Invest. 118, 3701-3713 (2008).
11. Fessler, M. B. & Parks, J. S. Intracellular lipid flux andmembrane microdomains as organizing principles in inflammatory cell signaling. J. Immunol. 187, 1529-1535 (2011).
12. Mendez, A. J. et al. Membrane lipid domains distinct from cholesterol/sphingomyelin-rich rafts are involved in the ABCA1-mediated lipid secretory pathway. J. Biol. Chem. 276, 3158-3166 (2001).
13. Murphy, A. J. et al. High-density lipoprotein reduces the human monocyte inflammatory response. Arterioscler. Thromb. Vasc. Biol. 28, 2071-2077 (2008).
14. Noghero, A. et al. Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2. Arterioscler. Thromb. Vasc. Biol. 32, 2280-2288 (2012).
15. Oshikawa, J. et al. Novel role of p66Shc in ROS-dependent VEGF signaling and angiogenesis in endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 302, H724-H732 (2012).
16. Ikeda, S. et al. Novel role of ARF6 in vascular endothelial growth factor-induced signaling and angiogenesis. Circ. Res. 96, 467-475 (2005).
17. Liao, W. x. et al. Compartmentalizing VEGF-induced ERK2/1 signaling in placental artery endothelial cell caveolae: a paradoxical role of caveolin-1 in placental angiogenesis in vitro. Mol. Endocrinol. 23, 1428-1444 (2009).
18. Eichmann, A. & Simons, M. VEGF signaling inside vascular endothelial cells and beyond. Curr. Opin. Cell Biol. 24, 188-193 (2012).
19. Lawson, N. D. & Weinstein, B. M. In vivo imaging of embryonic vascular development using transgenic zebrafish. Dev. Biol. 248, 307-318 (2002).
20. Torres-Vázquez, J. et al. Semaphorin-plexin signaling guides patterning of the developing vasculature. Dev. Cell 7, 117-123 (2004).
21. Dean, M. & Annilo, T. Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates. Annu. Rev. Genomics Hum. Genet. 6, 123-142 (2005).
22. Archer, A. et al. Transcriptional activity and developmental expression of liver X receptor (lxr) in Zebrafish. Dev. Dyn. 237, 1090-1098 (2008).
23. Whetzel, A. M. et al. ABCG1 deficiency in mice promotes endothelial activation and monocyte-endothelial interactions. Arterioscler. Thromb. Vasc. Biol. 30, 809-817 (2010).
24. Avraham-Davidi, I. et al. ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1. Nature Med. 18, 967-973 (2012).
25. Carmona, G. et al. Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis. Blood 113, 488-497 (2009).
26. Catanzariti, A. M., Soboleva, T. A., Jans, D. A., Board, P. G. & Baker, R. T. An efficient system for high-level expression and easy purification of authentic recombinant proteins. Protein Sci. 13, 1331-1339 (2004).
27. O'Connell, B. J. Cellular physiology of cholesterol efflux in vascular endothelial cells. Circulation 110, 2881-2888 (2004).
28. Fang, L. et al. Oxidized cholesteryl esters and phospholipids in zebrafish larvae fed a high cholesterol diet: macrophage binding and activation. J. Biol. Chem. 285, 32343-32351 (2010).
29. Gao, F. et al. L-5F, an apolipoprotein A-I mimetic, inhibits tumor angiogenesis by suppressing VEGF/basic FGF signaling pathways. Integr. Biol. 3, 479-489 (2011).
30. Bellacen, K. & Lewis, E. C. Aortic ring assay. J. Vis. Exp. 33, 1564 (2009).
31. Bolte, S.&Cordelieres, F. P.A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. 224, 213-232 (2006).
32. Chung,T.W. et al.GangliosideGM3inhibitsVEGF/VEGFR-2-mediatedangiogenesis: direct interaction of GM3 with VEGFR-2. Glycobiology 19, 229-239 (2009).
33. Chi, N. C. et al. Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. Genes Dev. 22, 734-739 (2008).
34. Westerfield, M.The ZebrafishBook:AGuide for the Laboratory Use of Zebrafish (Danio rerio) 5th edn (Univ. of Oregon Press, 2007).
35. Stoletov, K. et al. Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish. Circ. Res. 104, 952-960 (2009).
36. Owen, D. M., Rentero, C., Magenau, A., Abu-Siniyeh, A. & Gaus, K. Quantitative imaging of membrane lipid order in cells and organisms. Nature Protocols 7, 24-35 (2012).
37. Gaus, K., Le Lay, S., Balasubramanian, N. & Schwartz, M. A. Integrin-mediated adhesion regulates membrane order. J. Cell Biol. 174, 725-734 (2006).
38. Thisse, C. & Thisse, B. High-resolution in situ hybridization to whole-mount zebrafish embryos. Nature Protocols 3, 59-69 (2008).
39. Siekmann, A. F.&Lawson, N. D.Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature 445, 781-784 (2007).
40. Lawson, N. D. et al. Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development 128, 3675-3683 (2001).
41. Jowett, T. Analysis of protein and gene expression. Methods Cell Biol. 59, 63-85 (1998).
42. Schwend, T., Loucks, E. J., Snyder, D. & Ahlgren, S. C. Requirement of Npc1 and availability of cholesterol for early embryonic cell movements in zebrafish. J. Lipid Res. 52, 1328-1344 (2011).