Augmented angiogenesis in adventitia promotes growth of atherosclerotic plaque in apolipoprotein E-deficient mice

Atherosclerosis

Volumn 215, Issue 2, 2011, Pages 366-373

  Tanaka, Kimie ^a   Nagata, Daisuke ^a   Hirata, Yasunobu ^a   Tabata, Yasuhiko ^b   Nagai, Ryozo ^c   Sata, Masataka ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Adventitia; Atherosclerosis; Vasa vasorum

Indexed keywords

APOLIPOPROTEIN E; BASIC FIBROBLAST GROWTH FACTOR; MICROSPHERE;

ABDOMINAL AORTA; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL WALL; CAPILLARY; CONTROLLED STUDY; FEMALE; HYPERLIPIDEMIA; MACROPHAGE; MALE; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; RETROPERITONEUM; VASA VASORUM;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CONNECTIVE TISSUE; DISEASE PROGRESSION; FIBROBLAST GROWTH FACTOR 2; MALE; MICE; MICE, KNOCKOUT; NEOVASCULARIZATION, PATHOLOGIC; PLAQUE, ATHEROSCLEROTIC; VASA VASORUM;

EID: 79953045376     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.01.016     Document Type: Article

References (19)

1. Heistad D.D., Marcus M.L., Law E.G., et al. Regulation of blood flow to the aortic media in dogs. J Clin Invest 1978, 62:133-140.
2. Barger A.C., Beeuwkes R., Lainey L.L., et al. Hypothesis: vasa vasorum and neovascularization of human coronary arteries. A possible role in the pathophysiology of atherosclerosis. N Engl J Med 1984, 310:175-177.
3. Gossl M., Versari D., Hildebrandt H.A., et al. Segmental heterogeneity of vasa vasorum neovascularization in human coronary atherosclerosis. JACC Cardiovasc Imaging 2010, 3:32-40.
4. Moulton K.S. Angiogenesis in atherosclerosis: gathering evidence beyond speculation. Curr Opin Lipidol 2006, 17:548-555.
5. Moreno P.R., Purushothaman K.R., Fuster V., et al. Plaque neovascularization is increased in ruptured atherosclerotic lesions of human aorta: implications for plaque vulnerability. Circulation 2004, 110:2032-2038.
6. Wilson S.H., Herrmann J., Lerman L.O., et al. Simvastatin preserves the structure of coronary adventitial vasa vasorum in experimental hypercholesterolemia independent of lipid lowering. Circulation 2002, 105:415-418.
7. Kampschulte M., Brinkmann A., Stieger P., et al. Quantitative CT imaging of the spatio-temporal distribution patterns of vasa vasorum in aortas of apoE-/-/LDL-/- double knockout mice. Atherosclerosis 2010, 212:444-450.
8. Henrichot E., Juge-Aubry C.E., Pernin A., et al. Production of chemokines by perivascular adipose tissue: a role in the pathogenesis of atherosclerosis?. Arterioscler Thromb Vasc Biol 2005, 25:2594-2599.
9. Zhang S.H., Reddick R.L., Piedrahita J.A., et al. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 1992, 258:468-471.
10. Tabata Y., Ikada Y. Vascularization effect of basic fibroblast growth factor released from gelatin hydrogels with different biodegradabilities. Biomaterials 1999, 20:2169-2175.
11. Hosaka A., Koyama H., Kushibiki T., et al. Gelatin hydrogel microspheres enable pinpoint delivery of basic fibroblast growth factor for the development of functional collateral vessels. Circulation 2004, 110:3322-3328.
12. Thurston G., Murphy T.J., Baluk P., et al. Angiogenesis in mice with chronic airway inflammation: strain-dependent differences. Am J Pathol 1998, 153:1099-1112.
13. Tanaka K., Sata M., Fukuda D., et al. Age-associated aortic stenosis in apolipoprotein E-deficient mice. J Am Coll Cardiol 2005, 46:134-141.
14. Sokal R.R., Rohlf F.J. Comparison of regression lines. Biometry 1981, 499-509. Freeman & Co, New York, NY. R.R. Sokal, F.J. Rohlf (Eds.).
15. Thurston G., Baluk P., Hirata A., et al. Permeability-related changes revealed at endothelial cell borders in inflamed venules by lectin binding. Am J Physiol 1996, 271:H2547-H2562.
16. Khurana R., Zhuang Z., Bhardwaj S., et al. Angiogenesis-dependent and independent phases of intimal hyperplasia. Circulation 2004, 110:2436-2443.
17. Cuevas P., Gonzalez A.M., Carceller F., et al. Vascular response to basic fibroblast growth factor when infused onto the normal adventitia or into the injured media of the rat carotid artery. Circ Res 1991, 69:360-369.
18. Edelman E.R., Nugent M.A., Smith L.T., et al. Basic fibroblast growth factor enhances the coupling of intimal hyperplasia and proliferation of vasa vasorum in injured rat arteries. J Clin Invest 1992, 89:465-473.
19. Nakashima Y., Plump A.S., Raines E.W., et al. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb 1994, 14:133-140.