Hydrogen peroxide induces S1P1 receptors and sensitizes vascular endothelial cells to sphingosine 1-phosphate, a platelet-derived lipid mediator

American Journal of Physiology - Cell Physiology

Volumn 292, Issue 2, 2007, Pages

  Igarashi, Junsuke ^a,b   Miyoshi, Megumi ^a   Hashimoto, Takeshi ^a   Kubota, Yasuo ^a   Kosaka, Hiroaki ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b KAGAWA UNIVERSITY   (Japan)

Author keywords

G protein coupled receptors; Reactive oxygen species; Signal transduction; Sphingolipids

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROGEN PEROXIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; VASCULOTROPIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; UPREGULATION; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD PLATELETS; CATTLE; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; HYDROGEN PEROXIDE; LYSOPHOSPHOLIPIDS; MAP KINASE SIGNALING SYSTEM; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; RECEPTORS, LYSOSPHINGOLIPID; SIGNAL TRANSDUCTION; SPHINGOSINE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

BOVINAE;

EID: 33847063862     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00117.2006     Document Type: Article

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