The phosphatidylserine receptor mediates phagocytosis by vascular smooth muscle cells

Journal of Pathology

Volumn 212, Issue 3, 2007, Pages 249-259

  Kolb, S ^a   Vranckx, R ^a,b   Huisse, M G ^a,c   Michel, J B ^a   Meilhac, O ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c BICHAT HOSPITAL   (France)

Author keywords

Apoptosis; Atherosclerosis; Intraplaque haemorrhage; Senescent erythrocytes

Indexed keywords

HEMOGLOBIN; PEROXIDASE; PHOSPHATIDYLSERINE RECEPTOR; RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANALYSIS OF VARIANCE; APOPTOSIS; ARTERY WALL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; CELL AGING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CYTOFLUOROMETRY; ERYTHROCYTE LIFESPAN; ERYTHROPHAGOCYTOSIS; FISHER EXACT TEST; GENETIC TRANSFECTION; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; WOUND HEALING;

ANTIBODIES, MONOCLONAL; APOPTOSIS; BLOTTING, WESTERN; CAROTID ARTERIES; CAROTID STENOSIS; CELL AGING; CELLS, CULTURED; ERYTHROCYTE AGING; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MICROSCOPY, CONFOCAL; MYOCYTES, SMOOTH MUSCLE; PHAGOCYTOSIS; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TIME FACTORS;

EID: 34347346141     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2190     Document Type: Article

References (37)

1. Morris MR, Doull IJ, Dewitt S, Hallett MB. Reduced iC3b-mediated phagocytotic capacity of pulmonary neutrophils in cystic fibrosis. Clin Exp Immunol 2005;142:68-75.
2. Donnelly S, Roake W, Brown S, Young P, Naik H, Wordsworth P, et al. Impaired recognition of apoptotic neutrophils by the C1q/calreticulin and CD91 pathway in systemic lupus erythematosus. Arthritis Rheum 2006;54:1543-1556.
3. Bennett MR, Gibson DF, Schwartz SM, Tait JF. Binding and phagocytosis of apoptotic vascular smooth muscle cells is mediated in part by exposure of phosphatidylserine. Circ Res 1995;77:1136-1142.
4. Bennett MR, Boyle JJ. Apoptosis of vascular smooth muscle cells in atherosclerosis. Atherosclerosis 1998;138:3-9.
5. Lesauskaite V, Ivanoviene L, Valanciute A. [Programmed cellular death and atherogenesis: from molecular mechanisms to clinical aspects]. Medicina (Kaunas) 2003;39:529-534.
6. Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGFβ, PGE2, and PAF. J Clin Invest 1998; 101:890-898.
7. Devitt A, Pierce S, Oldreive C, Shingler WH, Gregory CD. CD14-dependent clearance of apoptotic cells by human macrophages: the role of phosphatidylserine. Cell Death Differ 2003;10:371-382.
8. Schrijvers DM, De Meyer GR, Kockx MM, Herman AG, Martinet W. Phagocytosis of apoptotic cells by macrophages is impaired in atherosclerosis. Arterioscler Thromb Vasc Biol 2005; 25:1256-1261.
9. Campbell GR, Uehara Y, Malmfors T, Burnstock G. Degeneration and regeneration of smooth muscle transplants in the anterior eye chamber. An ultrastructural study. Z Zellforsch Mikrosk Anat 1971; 117:155-175.
10. Joris I, Majno G. Cellular breakdown within the arterial wall. An ultrastructural study of the coronary artery in young and aging rats. Virchows Arch A Pathol Anat Histol 1974;364:111-127.
11. Garfield RE, Chacko S, Blose S. Phagocytosis by muscle cells. Lab Invest 1975;33:418-427.
12. Savill J, Hogg N, Ren Y, Haslett C. Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J Clin Invest 1992;90:1513-1522.
13. Flora PK, Gregory CD. Recognition of apoptotic cells by human macrophages: inhibition by a monocyte/macrophage-specific monoclonal antibody. Eur J Immunol 1994;24:2625-2632.
14. Platt N, Suzuki H, Kurihara Y, Kodama T, Gordon S. Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro. Proc Natl Acad Sci USA 1996;93:12 456-12 460.
15. Shiratsuchi A, Kawasaki Y, Ikemoto M, Arai H, Nakanishi Y. Role of class B scavenger receptor type I in phagocytosis of apoptotic rat spermatogenic cells by Sertoli cells. J Biol Chem 1999; 274:5901-5908.
16. Ramprasad MP, Fischer W, Witztum JL, Sambrano GR, Quehenberger O, Steinberg D. The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68. Proc Natl Acad Sci USA 1995;92:9580-9584.
17. Albert ML, Kim JI, Birge RB. αvβ5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells. Nat Cell Biol 2000;2:899-905.
18. Fadok VA, Bratton DL, Rose DM, Pearson A, Ezekewitz RA, Henson PM. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 2000;405:85-90.
19. Montano RF, Morrison SL. A colorimetric-enzymatic microassay for the quantitation of antibody-dependent complement activation. J Immunol Methods 1999;222:73-82.
20. Wood BL, Gibson DF, Tait JF. Increased erythrocyte phosphatidylserine exposure in sickle cell disease: flow-cytometric measurement and clinical associations. Blood 1996;88:1873-1880.
21. Martin-Ventura JL, Nicolas V, Houard X, Blanco-Colio LM, Leclercq A, Egido, J, et al. Biological significance of decreased HSP27 in human atherosclerosis. Arterioscler Thromb Vasc Biol 2006; 26:1337-1343.
22. Meilhac O, Ho-Tin-Noe B, Houard X, Philippe M, Michel JB, Angles-Cano E. Pericellular plasmin induces smooth muscle cell anoikis. FASEB J 2003;17:1301-1303.
23. Zhao GF, Seng JJ, Zhang H, She MP. Effects of oxidized low density lipoprotein on the growth of human artery smooth muscle cells. Chin Med J (Engl) 2005;118:1973-1978.
24. Leclercq A, Houard X, Loyau S, Philippe M, Sebbag U, Meilhac O, et al. Topology of protease activities reflects atherothrombotic plaque complexity. Atherosclerosis 2007;191:1-10.
25. Takaya N, Yuan C, Chu B, Saarn T, Polissar NL, Jarvik GP, et al. Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques: a high-resolution magnetic resonance imaging study. Circulation 2005;111:2768-2775.
26. Takaya N, Yuan C, Chu B, Saarn T, Underhill H, Cai J, et al. Association between carotid plaque characteristics and subsequent ischernic cerebrovascular events: a prospective assessment with MRI - initial results. Stroke 2006;37:818-823.
27. Kolodgie FD, Gold HK, Burke AP, Fowler DR, Kruth HS, Weber DK, et al. In traplaque hemorrhage and progression of coronary atheroma. N Engl J Med 2003;349:2316-2325.
28. Weidenbach H, Massmann J. Erythrocytophagocytosis by arterial smooth muscle cells in experimental atherosclerosis. Exp Pathol (Jena) 1978;15:111-115.
29. Gigli 1, Nelson RA Jr. Complement dependent immune phagocytosis. 1. Requirements for C′ 1, C′ 4, C′ 2, C′ 3. Exp Cell Res 1968;51:45-67.
30. Eto H, Miyata M, Kume N, Minami M, Itabe H, Orihara K, et al. Expression of lectin-like oxidized LDL receptor-1 in smooth muscle cells after vascular injury. Biochem Biophys Res Commun 2006; 341:591-598.
31. Cui P, Qin B, Liu N, Pan G, Pei D. Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals. Exp Cell Res 2004;293:154-163.
32. Cikala M, Alexandrova O, David CN, Proschel M, Stiening B, Cramer P, et al. The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II)-dependent oxygenase activity. BMC Cell Biol 2004;5:26.
33. Mitchell JE, Cvetanovic M, Tibrewal N, Patel V, Colamonici OR, Li MO, et al. The presumptive phosphatidylserine receptor is dispensable for innate anti-inflammatory recognition and clearance of apoptotic cells. J Biol Chem 2006;281:5718-5725.
34. Clancy RM, Neufing PJ, Zheng P, O'Mahony M, Nimmerjahn F, Gordon TP, et al. Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block. J Clin Invest 2006;116:2413-2422.
35. Pamaik R, Raff MC, Scholes J. Differences between the clearance of apoptotic cells by professional and non-professional phagocytes. Curr Biol 2000;10:857-860.
36. Jersmann HP, Ross KA, Vivers S, Brown SB, Haslett C, Dransfield I. Phagocytosis of apoptotic cells by human macrophages: analysis by multiparameter flow cytometry. Cytometry A 2003;51:7-15.
37. Fries DM, Lightfoot R, Koval M, Ischiropoulos H. Autologous apoptotic cell engulfment stimulates chemokine secretion by vascular smooth muscle cells. Am J Pathol 2005;167:345-353.