-
1
-
-
38549152194
-
Principles of bioactive lipid signalling: Lessons from sphingolipids
-
Hannun YA, &, Obeid LM, (2008) Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol 9, 139-150.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 139-150
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
3
-
-
64149110203
-
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: A novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals
-
Zitomer NC, Mitchell T, Voss KA, Bondy GS, Pruett ST, Garnier-Amblard EC, Liebeskind LS, Park H, Wang E, Sullards MC, et al,. (2009) Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals. J Biol Chem 284, 4786-4795.
-
(2009)
J Biol Chem
, vol.284
, pp. 4786-4795
-
-
Zitomer, N.C.1
Mitchell, T.2
Voss, K.A.3
Bondy, G.S.4
Pruett, S.T.5
Garnier-Amblard, E.C.6
Liebeskind, L.S.7
Park, H.8
Wang, E.9
Sullards, M.C.10
-
4
-
-
77951218516
-
Hereditary sensory neuropathy type 1 is caused by the accumulation of two neurotoxic sphingolipids
-
Penno A, Reilly MM, Houlden H, Laura M, Rentsch K, Niederkofler V, Stoeckli ET, Nicholson G, Eichler F, Brown RH Jr, et al,. (2010) Hereditary sensory neuropathy type 1 is caused by the accumulation of two neurotoxic sphingolipids. J Biol Chem 285, 11178-11187.
-
(2010)
J Biol Chem
, vol.285
, pp. 11178-11187
-
-
Penno, A.1
Reilly, M.M.2
Houlden, H.3
Laura, M.4
Rentsch, K.5
Niederkofler, V.6
Stoeckli, E.T.7
Nicholson, G.8
Eichler, F.9
Brown, Jr.R.H.10
-
5
-
-
84863880532
-
Glycosphingolipid functions
-
doi: 10.1101/cshperspect.a004788
-
Lingwood CA, (2011) Glycosphingolipid functions. Cold Spring Harb Perspect Biol 3, doi: 10.1101/cshperspect.a004788.
-
(2011)
Cold Spring Harb Perspect Biol
, vol.3
-
-
Lingwood, C.A.1
-
6
-
-
79960778361
-
Still benched on its way to the bedside: Sphingosine kinase 1 as an emerging target in cancer chemotherapy
-
Gault CR, &, Obeid LM, (2011) Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy. Crit Rev Biochem Mol Biol 46, 342-351.
-
(2011)
Crit Rev Biochem Mol Biol
, vol.46
, pp. 342-351
-
-
Gault, C.R.1
Obeid, L.M.2
-
7
-
-
0038218405
-
Sphingosine-1-phosphate: An enigmatic signalling lipid
-
Spiegel S, &, Milstien S, (2003) Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol 4, 397-407.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
-
8
-
-
2442699980
-
Sphingosine-1-phosphate receptors: Receptor specificity versus functional redundancy
-
Taha TA, Argraves KM, &, Obeid LM, (2004) Sphingosine-1-phosphate receptors: receptor specificity versus functional redundancy. Biochim Biophys Acta 1682, 48-55.
-
(2004)
Biochim Biophys Acta
, vol.1682
, pp. 48-55
-
-
Taha, T.A.1
Argraves, K.M.2
Obeid, L.M.3
-
9
-
-
33750832270
-
Role of ABCC1 in export of sphingosine-1-phosphate from mast cells
-
Mitra P, Oskeritzian CA, Payne SG, Beaven MA, Milstien S, &, Spiegel S, (2006) Role of ABCC1 in export of sphingosine-1-phosphate from mast cells. Proc Natl Acad Sci USA 103, 16394-16399.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16394-16399
-
-
Mitra, P.1
Oskeritzian, C.A.2
Payne, S.G.3
Beaven, M.A.4
Milstien, S.5
Spiegel, S.6
-
10
-
-
0035929556
-
Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: Modulation of cellular activity of sphingosine 1-phosphate
-
Boujaoude LC, Bradshaw-Wilder C, Mao C, Cohn J, Ogretmen B, Hannun YA, &, Obeid LM, (2001) Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate. J Biol Chem 276, 35258-35264.
-
(2001)
J Biol Chem
, vol.276
, pp. 35258-35264
-
-
Boujaoude, L.C.1
Bradshaw-Wilder, C.2
Mao, C.3
Cohn, J.4
Ogretmen, B.5
Hannun, Y.A.6
Obeid, L.M.7
-
11
-
-
84862188843
-
Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells
-
Hisano Y, Kobayashi N, Yamaguchi A, &, Nishi T, (2012) Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells. PLoS ONE 7, e38941.
-
(2012)
PLoS ONE
, vol.7
-
-
Hisano, Y.1
Kobayashi, N.2
Yamaguchi, A.3
Nishi, T.4
-
12
-
-
0028956049
-
Involvement of a pertussis toxin-sensitive G protein in the mitogenic signaling pathways of sphingosine 1-phosphate
-
Goodemote KA, Mattie ME, Berger A, &, Spiegel S, (1995) Involvement of a pertussis toxin-sensitive G protein in the mitogenic signaling pathways of sphingosine 1-phosphate. J Biol Chem 270, 10272-10277.
-
(1995)
J Biol Chem
, vol.270
, pp. 10272-10277
-
-
Goodemote, K.A.1
Mattie, M.E.2
Berger, A.3
Spiegel, S.4
-
13
-
-
0030023697
-
Activation of a high affinity Gi protein-coupled plasma membrane receptor by sphingosine-1-phosphat
-
e
-
van Koppen C, Meyer zu Heringdorf M, Laser KT, Zhang C, Jakobs KH, Bunemann M, &, Pott L, (1996) Activation of a high affinity Gi protein-coupled plasma membrane receptor by sphingosine-1-phosphat e J Biol Chem 271, 2082-2087.
-
(1996)
J Biol Chem
, vol.271
, pp. 2082-2087
-
-
Van Koppen, C.1
Meyer Zu Heringdorf, M.2
Laser, K.T.3
Zhang, C.4
Jakobs, K.H.5
Bunemann, M.6
Pott, L.7
-
14
-
-
0025311299
-
An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors
-
Hla T, &, Maciag T, (1990) An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors. J Biol Chem 265, 9308-9313.
-
(1990)
J Biol Chem
, vol.265
, pp. 9308-9313
-
-
Hla, T.1
MacIag, T.2
-
15
-
-
0032489574
-
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
-
Lee MJ, Van Brocklyn JR, Thangada S, Liu CH, Hand AR, Menzeleev R, Spiegel S, &, Hla T, (1998) Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 279, 1552-1555.
-
(1998)
Science
, vol.279
, pp. 1552-1555
-
-
Lee, M.J.1
Van Brocklyn, J.R.2
Thangada, S.3
Liu, C.H.4
Hand, A.R.5
Menzeleev, R.6
Spiegel, S.7
Hla, T.8
-
16
-
-
0027292372
-
Molecular cloning of a novel putative G protein-coupled receptor expressed in the cardiovascular system
-
Okazaki H, Ishizaka N, Sakurai T, Kurokawa K, Goto K, Kumada M, &, Takuwa Y, (1993) Molecular cloning of a novel putative G protein-coupled receptor expressed in the cardiovascular system. Biochem Biophys Res Commun 190, 1104-1109.
-
(1993)
Biochem Biophys Res Commun
, vol.190
, pp. 1104-1109
-
-
Okazaki, H.1
Ishizaka, N.2
Sakurai, T.3
Kurokawa, K.4
Goto, K.5
Kumada, M.6
Takuwa, Y.7
-
17
-
-
0030583616
-
Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9
-
Yamaguchi F, Tokuda M, Hatase O, &, Brenner S, (1996) Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9. Biochem Biophys Res Commun 227, 608-614.
-
(1996)
Biochem Biophys Res Commun
, vol.227
, pp. 608-614
-
-
Yamaguchi, F.1
Tokuda, M.2
Hatase, O.3
Brenner, S.4
-
18
-
-
0032532764
-
EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue
-
Graler MH, Bernhardt G, &, Lipp M, (1998) EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue. Genomics 53, 164-169.
-
(1998)
Genomics
, vol.53
, pp. 164-169
-
-
Graler, M.H.1
Bernhardt, G.2
Lipp, M.3
-
19
-
-
0034097714
-
Sphingosine 1-phosphate: A ligand for the EDG-1 family of G-protein-coupled receptors
-
Spiegel S, (2000) Sphingosine 1-phosphate: a ligand for the EDG-1 family of G-protein-coupled receptors. Ann NY Acad Sci 905, 54-60.
-
(2000)
Ann NY Acad Sci
, vol.905
, pp. 54-60
-
-
Spiegel, S.1
-
20
-
-
84884211437
-
Dissecting the role of the S1P/S1PR axis in health and disease
-
Aarthi JJ, Darendeliler MA, &, Pushparaj PN, (2011) Dissecting the role of the S1P/S1PR axis in health and disease. J Dental Res 90, 841-854.
-
(2011)
J Dental Res
, vol.90
, pp. 841-854
-
-
Aarthi, J.J.1
Darendeliler, M.A.2
Pushparaj, P.N.3
-
21
-
-
18144420388
-
The G protein-coupled receptor S1P2 regulates Rho/Rho kinase pathway to inhibit tumor cell migration
-
Lepley D, Paik JH, Hla T, &, Ferrer F, (2005) The G protein-coupled receptor S1P2 regulates Rho/Rho kinase pathway to inhibit tumor cell migration. Cancer Res 65, 3788-3795.
-
(2005)
Cancer Res
, vol.65
, pp. 3788-3795
-
-
Lepley, D.1
Paik, J.H.2
Hla, T.3
Ferrer, F.4
-
22
-
-
1642580757
-
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
-
Matloubian M, Lo CG, Cinamon G, Lesneski MJ, Xu Y, Brinkmann V, Allende ML, Proia RL, &, Cyster JG, (2004) Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 427, 355-360.
-
(2004)
Nature
, vol.427
, pp. 355-360
-
-
Matloubian, M.1
Lo, C.G.2
Cinamon, G.3
Lesneski, M.J.4
Xu, Y.5
Brinkmann, V.6
Allende, M.L.7
Proia, R.L.8
Cyster, J.G.9
-
23
-
-
79958205590
-
Fingolimod: An oral disease-modifying therapy for relapsing multiple sclerosis
-
Yeh EA, &, Weinstock-Guttman B, (2011) Fingolimod: an oral disease-modifying therapy for relapsing multiple sclerosis. Adv Ther 28, 270-278.
-
(2011)
Adv Ther
, vol.28
, pp. 270-278
-
-
Yeh, E.A.1
Weinstock-Guttman, B.2
-
24
-
-
80052655561
-
FTY720 blocks egress of T cells in part by abrogation of their adhesion on the lymph node sinus
-
Zhi L, Kim P, Thompson BD, Pitsillides C, Bankovich AJ, Yun SH, Lin CP, Cyster JG, &, Wu MX, (2011) FTY720 blocks egress of T cells in part by abrogation of their adhesion on the lymph node sinus. J Immunol 187, 2244-2251.
-
(2011)
J Immunol
, vol.187
, pp. 2244-2251
-
-
Zhi, L.1
Kim, P.2
Thompson, B.D.3
Pitsillides, C.4
Bankovich, A.J.5
Yun, S.H.6
Lin, C.P.7
Cyster, J.G.8
Wu, M.X.9
-
25
-
-
3042743990
-
FTY720: Sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function
-
Brinkmann V, Cyster JG, &, Hla T, (2004) FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function. Am J Transplant 4, 1019-1025.
-
(2004)
Am J Transplant
, vol.4
, pp. 1019-1025
-
-
Brinkmann, V.1
Cyster, J.G.2
Hla, T.3
-
26
-
-
51649099579
-
2+ signaling pathways
-
2+ signaling pathways. Blood 112, 1129-1138.
-
(2008)
Blood
, vol.112
, pp. 1129-1138
-
-
Yoon, C.M.1
Hong, B.S.2
Moon, H.G.3
Lim, S.4
Suh, P.G.5
Kim, Y.K.6
Chae, C.B.7
Gho, Y.S.8
-
27
-
-
33644880217
-
Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 signaling in rheumatoid synovium: Regulation of synovial proliferation and inflammatory gene expression
-
Kitano M, Hla T, Sekiguchi M, Kawahito Y, Yoshimura R, Miyazawa K, Iwasaki T, Sano H, Saba JD, &, Tam YY, (2006) Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 signaling in rheumatoid synovium: regulation of synovial proliferation and inflammatory gene expression. Arthr Rheum 54, 742-753.
-
(2006)
Arthr Rheum
, vol.54
, pp. 742-753
-
-
Kitano, M.1
Hla, T.2
Sekiguchi, M.3
Kawahito, Y.4
Yoshimura, R.5
Miyazawa, K.6
Iwasaki, T.7
Sano, H.8
Saba, J.D.9
Tam, Y.Y.10
-
28
-
-
36148971252
-
Sphingosine 1-phosphate receptor 2 negatively regulates neointimal formation in mouse arteries
-
Shimizu T, Nakazawa T, Cho A, Dastvan F, Shilling D, Daum G, &, Reidy MA, (2007) Sphingosine 1-phosphate receptor 2 negatively regulates neointimal formation in mouse arteries. Circ Res 101, 995-1000.
-
(2007)
Circ Res
, vol.101
, pp. 995-1000
-
-
Shimizu, T.1
Nakazawa, T.2
Cho, A.3
Dastvan, F.4
Shilling, D.5
Daum, G.6
Reidy, M.A.7
-
29
-
-
60849110803
-
S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor
-
Li MH, Sanchez T, Yamase H, Hla T, Oo ML, Pappalardo A, Lynch KR, Lin CY, &, Ferrer F, (2009) S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor. Cancer Lett 276, 171-179.
-
(2009)
Cancer Lett
, vol.276
, pp. 171-179
-
-
Li, M.H.1
Sanchez, T.2
Yamase, H.3
Hla, T.4
Oo, M.L.5
Pappalardo, A.6
Lynch, K.R.7
Lin, C.Y.8
Ferrer, F.9
-
30
-
-
9644252866
-
Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference
-
Chae SS, Paik JH, Furneaux H, &, Hla T, (2004) Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference. J Clin Invest 114, 1082-1089.
-
(2004)
J Clin Invest
, vol.114
, pp. 1082-1089
-
-
Chae, S.S.1
Paik, J.H.2
Furneaux, H.3
Hla, T.4
-
31
-
-
84865405053
-
Dendritic cell sphingosine 1-phosphate receptor-3 regulates Th1-Th2 polarity in kidney ischemia-reperfusion injury
-
Bajwa A, Huang L, Ye H, Dondeti K, Song S, Rosin DL, Lynch KR, Lobo PI, Li L, &, Okusa MD, (2012) Dendritic cell sphingosine 1-phosphate receptor-3 regulates Th1-Th2 polarity in kidney ischemia-reperfusion injury. J Immunol 189, 2584-2596.
-
(2012)
J Immunol
, vol.189
, pp. 2584-2596
-
-
Bajwa, A.1
Huang, L.2
Ye, H.3
Dondeti, K.4
Song, S.5
Rosin, D.L.6
Lynch, K.R.7
Lobo, P.I.8
Li, L.9
Okusa, M.D.10
-
32
-
-
77956568581
-
Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions
-
Van Doorn R, Van Horssen J, Verzijl D, Witte M, Ronken E, Van Het Hof B, Lakeman K, Dijkstra CD, Van Der Valk P, Reijerkerk A, et al,. (2010) Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions. Glia 58, 1465-1476.
-
(2010)
Glia
, vol.58
, pp. 1465-1476
-
-
Van Doorn, R.1
Van Horssen, J.2
Verzijl, D.3
Witte, M.4
Ronken, E.5
Van Het Hof, B.6
Lakeman, K.7
Dijkstra, C.D.8
Van Der Valk, P.9
Reijerkerk, A.10
-
33
-
-
80051991367
-
Sphingosine kinase 1 and sphingosine 1-phosphate receptor 3 are functionally upregulated on astrocytes under pro-inflammatory conditions
-
Fischer I, Alliod C, Martinier N, Newcombe J, Brana C, &, Pouly S, (2011) Sphingosine kinase 1 and sphingosine 1-phosphate receptor 3 are functionally upregulated on astrocytes under pro-inflammatory conditions. PLoS ONE 6, e23905.
-
(2011)
PLoS ONE
, vol.6
-
-
Fischer, I.1
Alliod, C.2
Martinier, N.3
Newcombe, J.4
Brana, C.5
Pouly, S.6
-
34
-
-
84868328440
-
Sphingosine-1-phosphate receptor-3 is a novel biomarker in acute lung injury
-
Sun X, Singleton PA, Letsiou E, Zhao J, Belvitch P, Sammani S, Chiang ET, Moreno-Vinasco L, Wade MS, Zhou T, et al,. (2012) Sphingosine-1-phosphate receptor-3 is a novel biomarker in acute lung injury. Am J Resp Cell Mol Biol 47, 628-636.
-
(2012)
Am J Resp Cell Mol Biol
, vol.47
, pp. 628-636
-
-
Sun, X.1
Singleton, P.A.2
Letsiou, E.3
Zhao, J.4
Belvitch, P.5
Sammani, S.6
Chiang, E.T.7
Moreno-Vinasco, L.8
Wade, M.S.9
Zhou, T.10
-
35
-
-
79751527693
-
Sphingosine-1-phosphate receptor 3 promotes recruitment of monocyte/macrophages in inflammation and atherosclerosis
-
Keul P, Lucke S, von Wnuck Lipinski K, Bode C, Graler M, Heusch G, &, Levkau B, (2011) Sphingosine-1-phosphate receptor 3 promotes recruitment of monocyte/macrophages in inflammation and atherosclerosis. Circ Res 108, 314-323.
-
(2011)
Circ Res
, vol.108
, pp. 314-323
-
-
Keul, P.1
Lucke, S.2
Von Wnuck Lipinski, K.3
Bode, C.4
Graler, M.5
Heusch, G.6
Levkau, B.7
-
36
-
-
77950231687
-
Sphingosine 1-phosphate (S1P) regulates vascular contraction via S1P3 receptor: Investigation based on a new S1P3 receptor antagonist
-
Murakami A, Takasugi H, Ohnuma S, Koide Y, Sakurai A, Takeda S, Hasegawa T, Sasamori J, Konno T, Hayashi K, et al,. (2010) Sphingosine 1-phosphate (S1P) regulates vascular contraction via S1P3 receptor: investigation based on a new S1P3 receptor antagonist. Mol Pharmacol 77, 704-713.
-
(2010)
Mol Pharmacol
, vol.77
, pp. 704-713
-
-
Murakami, A.1
Takasugi, H.2
Ohnuma, S.3
Koide, Y.4
Sakurai, A.5
Takeda, S.6
Hasegawa, T.7
Sasamori, J.8
Konno, T.9
Hayashi, K.10
-
37
-
-
84860293201
-
Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells
-
Hsu A, Zhang W, Lee JF, An J, Ekambaram P, Liu J, Honn KV, Klinge CM, &, Lee MJ, (2012) Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells. Int J Oncol 40, 1619-1626.
-
(2012)
Int J Oncol
, vol.40
, pp. 1619-1626
-
-
Hsu, A.1
Zhang, W.2
Lee, J.F.3
An, J.4
Ekambaram, P.5
Liu, J.6
Honn, K.V.7
Klinge, C.M.8
Lee, M.J.9
-
38
-
-
33646117016
-
Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: The role of sphingosine kinase-1
-
Sukocheva O, Wadham C, Holmes A, Albanese N, Verrier E, Feng F, Bernal A, Derian CK, Ullrich A, Vadas MA, et al,. (2006) Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1. J Cell Biol 173, 301-310.
-
(2006)
J Cell Biol
, vol.173
, pp. 301-310
-
-
Sukocheva, O.1
Wadham, C.2
Holmes, A.3
Albanese, N.4
Verrier, E.5
Feng, F.6
Bernal, A.7
Derian, C.K.8
Ullrich, A.9
Vadas, M.A.10
-
39
-
-
0037684739
-
The sphingosine 1-phosphate receptor S1P4 regulates cell shape and motility via coupling to Gi and G12/13
-
Graler MH, Grosse R, Kusch A, Kremmer E, Gudermann T, &, Lipp M, (2003) The sphingosine 1-phosphate receptor S1P4 regulates cell shape and motility via coupling to Gi and G12/13. J Cell Biochem 89, 507-519.
-
(2003)
J Cell Biochem
, vol.89
, pp. 507-519
-
-
Graler, M.H.1
Grosse, R.2
Kusch, A.3
Kremmer, E.4
Gudermann, T.5
Lipp, M.6
-
40
-
-
26444606350
-
Type 4 sphingosine 1-phosphate G protein-coupled receptor (S1P4) transduces S1P effects on T cell proliferation and cytokine secretion without signaling migration
-
Wang W, Graeler MH, &, Goetzl EJ, (2005) Type 4 sphingosine 1-phosphate G protein-coupled receptor (S1P4) transduces S1P effects on T cell proliferation and cytokine secretion without signaling migration. FASEB J 19, 1731-1733.
-
(2005)
FASEB J
, vol.19
, pp. 1731-1733
-
-
Wang, W.1
Graeler, M.H.2
Goetzl, E.J.3
-
41
-
-
80355129639
-
Sphingosine-1-phospate receptor 4 (S1P(4)) deficiency profoundly affects dendritic cell function and TH17-cell differentiation in a murine model
-
Schulze T, Golfier S, Tabeling C, Rabel K, Graler MH, Witzenrath M, &, Lipp M, (2011) Sphingosine-1-phospate receptor 4 (S1P(4)) deficiency profoundly affects dendritic cell function and TH17-cell differentiation in a murine model. FASEB J 25, 4024-4036.
-
(2011)
FASEB J
, vol.25
, pp. 4024-4036
-
-
Schulze, T.1
Golfier, S.2
Tabeling, C.3
Rabel, K.4
Graler, M.H.5
Witzenrath, M.6
Lipp, M.7
-
42
-
-
13844271705
-
Edg8/S1P5: An oligodendroglial receptor with dual function on process retraction and cell survival
-
Jaillard C, Harrison S, Stankoff B, Aigrot MS, Calver AR, Duddy G, Walsh FS, Pangalos MN, Arimura N, Kaibuchi K, et al,. (2005) Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival. J Neurosci 25, 1459-1469.
-
(2005)
J Neurosci
, vol.25
, pp. 1459-1469
-
-
Jaillard, C.1
Harrison, S.2
Stankoff, B.3
Aigrot, M.S.4
Calver, A.R.5
Duddy, G.6
Walsh, F.S.7
Pangalos, M.N.8
Arimura, N.9
Kaibuchi, K.10
-
43
-
-
34247554847
-
Activation of sphingosine-1-phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration
-
Novgorodov AS, El-Alwani M, Bielawski J, Obeid LM, &, Gudz TI, (2007) Activation of sphingosine-1-phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration. FASEB J 21, 1503-1514.
-
(2007)
FASEB J
, vol.21
, pp. 1503-1514
-
-
Novgorodov, A.S.1
El-Alwani, M.2
Bielawski, J.3
Obeid, L.M.4
Gudz, T.I.5
-
44
-
-
80855156707
-
Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking
-
Mayol K, Biajoux V, Marvel J, Balabanian K, &, Walzer T, (2011) Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking. Blood 118, 4863-4871.
-
(2011)
Blood
, vol.118
, pp. 4863-4871
-
-
Mayol, K.1
Biajoux, V.2
Marvel, J.3
Balabanian, K.4
Walzer, T.5
-
45
-
-
70449732610
-
T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow
-
Jenne CN, Enders A, Rivera R, Watson SR, Bankovich AJ, Pereira JP, Xu Y, Roots CM, Beilke JN, Banerjee A, et al,. (2009) T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. J Exp Med 206, 2469-2481.
-
(2009)
J Exp Med
, vol.206
, pp. 2469-2481
-
-
Jenne, C.N.1
Enders, A.2
Rivera, R.3
Watson, S.R.4
Bankovich, A.J.5
Pereira, J.P.6
Xu, Y.7
Roots, C.M.8
Beilke, J.N.9
Banerjee, A.10
-
46
-
-
84862327950
-
Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier
-
van Doorn R, Lopes Pinheiro MA, Kooij G, Lakeman K, van het Hof B, van der Pol SM, Geerts D, van Horssen J, van der Valk P, van der Kam E, et al,. (2012) Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier. J Neuroinflammation 9, 133.
-
(2012)
J Neuroinflammation
, vol.9
, pp. 133
-
-
Van Doorn, R.1
Lopes Pinheiro, M.A.2
Kooij, G.3
Lakeman, K.4
Van Het Hof, B.5
Van Der Pol, S.M.6
Geerts, D.7
Van Horssen, J.8
Van Der Valk, P.9
Van Der Kam, E.10
-
47
-
-
68849112045
-
S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells
-
Chang CL, Ho MC, Lee PH, Hsu CY, Huang WP, &, Lee H, (2009) S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells. Am J Physiol 297, C451-C458.
-
(2009)
Am J Physiol
, vol.297
-
-
Chang, C.L.1
Ho, M.C.2
Lee, P.H.3
Hsu, C.Y.4
Huang, W.P.5
Lee, H.6
-
48
-
-
77951429040
-
Effect of S1P5 on proliferation and migration of human esophageal cancer cells
-
Hu WM, Li L, Jing BQ, Zhao YS, Wang CL, Feng L, &, Xie YE, (2010) Effect of S1P5 on proliferation and migration of human esophageal cancer cells. World J Gastroenterol 16, 1859-1866.
-
(2010)
World J Gastroenterol
, vol.16
, pp. 1859-1866
-
-
Hu, W.M.1
Li, L.2
Jing, B.Q.3
Zhao, Y.S.4
Wang, C.L.5
Feng, L.6
Xie, Y.E.7
-
49
-
-
34249280944
-
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN
-
Sanchez T, Skoura A, Wu MT, Casserly B, Harrington EO, &, Hla T, (2007) Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. Arterioscl Throm Vasc 27, 1312-1318.
-
(2007)
Arterioscl Throm Vasc
, vol.27
, pp. 1312-1318
-
-
Sanchez, T.1
Skoura, A.2
Wu, M.T.3
Casserly, B.4
Harrington, E.O.5
Hla, T.6
-
50
-
-
84862822407
-
LPS and TNF-alpha induce expression of sphingosine-1-phosphate receptor-2 in human microvascular endothelial cells
-
Du J, Zeng C, Li Q, Chen B, Liu H, Huang X, &, Huang Q, (2012) LPS and TNF-alpha induce expression of sphingosine-1-phosphate receptor-2 in human microvascular endothelial cells. Pathology Res Pract 208, 82-88.
-
(2012)
Pathology Res Pract
, vol.208
, pp. 82-88
-
-
Du, J.1
Zeng, C.2
Li, Q.3
Chen, B.4
Liu, H.5
Huang, X.6
Huang, Q.7
-
51
-
-
84857899576
-
Senescent endothelial dysfunction is attributed to the up-regulation of sphingosine-1-phosphate receptor-2 in aged rats
-
Lu H, Yuan H, Chen S, Huang L, Xiang H, Yang G, Deng H, &, Zhou J, (2012) Senescent endothelial dysfunction is attributed to the up-regulation of sphingosine-1-phosphate receptor-2 in aged rats. Mol Cell Biochem 363, 217-224.
-
(2012)
Mol Cell Biochem
, vol.363
, pp. 217-224
-
-
Lu, H.1
Yuan, H.2
Chen, S.3
Huang, L.4
Xiang, H.5
Yang, G.6
Deng, H.7
Zhou, J.8
-
52
-
-
57649194902
-
Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells
-
Estrada R, Zeng Q, Lu H, Sarojini H, Lee JF, Mathis SP, Sanchez T, Wang E, Kontos CD, Lin CY, et al,. (2008) Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells. J Biol Chem 283, 30363-30375.
-
(2008)
J Biol Chem
, vol.283
, pp. 30363-30375
-
-
Estrada, R.1
Zeng, Q.2
Lu, H.3
Sarojini, H.4
Lee, J.F.5
Mathis, S.P.6
Sanchez, T.7
Wang, E.8
Kontos, C.D.9
Lin, C.Y.10
-
53
-
-
34848892421
-
Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina
-
Skoura A, Sanchez T, Claffey K, Mandala SM, Proia RL, &, Hla T, (2007) Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina. J Clin Invest 117, 2506-2516.
-
(2007)
J Clin Invest
, vol.117
, pp. 2506-2516
-
-
Skoura, A.1
Sanchez, T.2
Claffey, K.3
Mandala, S.M.4
Proia, R.L.5
Hla, T.6
-
54
-
-
75749105853
-
Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic beta-cells
-
Imasawa T, Koike K, Ishii I, Chun J, &, Yatomi Y, (2010) Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic beta-cells. Biochem Biophys Res Commun 392, 207-211.
-
(2010)
Biochem Biophys Res Commun
, vol.392
, pp. 207-211
-
-
Imasawa, T.1
Koike, K.2
Ishii, I.3
Chun, J.4
Yatomi, Y.5
-
55
-
-
84155194947
-
Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes
-
Studer E, Zhou X, Zhao R, Wang Y, Takabe K, Nagahashi M, Pandak WM, Dent P, Spiegel S, Shi R, et al,. (2012) Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes. Hepatology 55, 267-276.
-
(2012)
Hepatology
, vol.55
, pp. 267-276
-
-
Studer, E.1
Zhou, X.2
Zhao, R.3
Wang, Y.4
Takabe, K.5
Nagahashi, M.6
Pandak, W.M.7
Dent, P.8
Spiegel, S.9
Shi, R.10
-
56
-
-
64349089268
-
Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2
-
Ikeda H, Watanabe N, Ishii I, Shimosawa T, Kume Y, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, et al,. (2009) Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2. J Lipid Res 50, 556-564.
-
(2009)
J Lipid Res
, vol.50
, pp. 556-564
-
-
Ikeda, H.1
Watanabe, N.2
Ishii, I.3
Shimosawa, T.4
Kume, Y.5
Tomiya, T.6
Inoue, Y.7
Nishikawa, T.8
Ohtomo, N.9
Tanoue, Y.10
-
57
-
-
77949518621
-
Essential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema
-
Oskeritzian CA, Price MM, Hait NC, Kapitonov D, Falanga YT, Morales JK, Ryan JJ, Milstien S, &, Spiegel S, (2010) Essential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema. J Exp Med 207, 465-474.
-
(2010)
J Exp Med
, vol.207
, pp. 465-474
-
-
Oskeritzian, C.A.1
Price, M.M.2
Hait, N.C.3
Kapitonov, D.4
Falanga, Y.T.5
Morales, J.K.6
Ryan, J.J.7
Milstien, S.8
Spiegel, S.9
-
58
-
-
77951817430
-
Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice
-
Olivera A, Eisner C, Kitamura Y, Dillahunt S, Allende L, Tuymetova G, Watford W, Meylan F, Diesner SC, Li L, et al,. (2010) Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice. J Clin Invest 120, 1429-1440.
-
(2010)
J Clin Invest
, vol.120
, pp. 1429-1440
-
-
Olivera, A.1
Eisner, C.2
Kitamura, Y.3
Dillahunt, S.4
Allende, L.5
Tuymetova, G.6
Watford, W.7
Meylan, F.8
Diesner, S.C.9
Li, L.10
-
59
-
-
77949332336
-
Inhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation
-
Michaud J, Im DS, &, Hla T, (2010) Inhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation. J Immunol 184, 1475-1483.
-
(2010)
J Immunol
, vol.184
, pp. 1475-1483
-
-
Michaud, J.1
Im, D.S.2
Hla, T.3
-
60
-
-
79955781310
-
Role of sphingosine-1-phosphate (S1P) and S1P receptor 2 in the phagocytosis of Cryptococcus neoformans by alveolar macrophages
-
McQuiston T, Luberto C, &, Del Poeta M, (2011) Role of sphingosine-1-phosphate (S1P) and S1P receptor 2 in the phagocytosis of Cryptococcus neoformans by alveolar macrophages. Microbiology 157, 1416-1427.
-
(2011)
Microbiology
, vol.157
, pp. 1416-1427
-
-
McQuiston, T.1
Luberto, C.2
Del Poeta, M.3
-
61
-
-
52449133460
-
G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase
-
Takashima S, Sugimoto N, Takuwa N, Okamoto Y, Yoshioka K, Takamura M, Takata S, Kaneko S, &, Takuwa Y, (2008) G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase. Cardiovasc Res 79, 689-697.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 689-697
-
-
Takashima, S.1
Sugimoto, N.2
Takuwa, N.3
Okamoto, Y.4
Yoshioka, K.5
Takamura, M.6
Takata, S.7
Kaneko, S.8
Takuwa, Y.9
-
62
-
-
70349561517
-
Sphingosine-1-phosphate receptor-2 regulates expression of smooth muscle alpha-actin after arterial injury
-
Grabski AD, Shimizu T, Deou J, Mahoney WM Jr, Reidy MA, &, Daum G, (2009) Sphingosine-1-phosphate receptor-2 regulates expression of smooth muscle alpha-actin after arterial injury. Arterioscl Throm Vasc 29, 1644-1650.
-
(2009)
Arterioscl Throm Vasc
, vol.29
, pp. 1644-1650
-
-
Grabski, A.D.1
Shimizu, T.2
Deou, J.3
Mahoney, Jr.W.M.4
Reidy, M.A.5
Daum, G.6
-
63
-
-
84861014560
-
Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway
-
Loh KC, Leong WI, Carlson ME, Oskouian B, Kumar A, Fyrst H, Zhang M, Proia RL, Hoffman EP, &, Saba JD, (2012) Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway. PLoS ONE 7, e37218.
-
(2012)
PLoS ONE
, vol.7
-
-
Loh, K.C.1
Leong, W.I.2
Carlson, M.E.3
Oskouian, B.4
Kumar, A.5
Fyrst, H.6
Zhang, M.7
Proia, R.L.8
Hoffman, E.P.9
Saba, J.D.10
-
64
-
-
77955985369
-
Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation
-
Medlin MD, Staus DP, Dubash AD, Taylor JM, &, Mack CP, (2010) Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation. Arterioscl Throm Vasc 30, 1779-1786.
-
(2010)
Arterioscl Throm Vasc
, vol.30
, pp. 1779-1786
-
-
Medlin, M.D.1
Staus, D.P.2
Dubash, A.D.3
Taylor, J.M.4
MacK, C.P.5
-
65
-
-
77955276223
-
Downregulation of sphingosine-1-phosphate receptors in bronchial smooth muscle of mouse experimental asthma
-
Chiba Y, Suzuki K, Uechi M, Kurihara E, Goto K, Sakai H, &, Misawa M, (2010) Downregulation of sphingosine-1-phosphate receptors in bronchial smooth muscle of mouse experimental asthma. Pharmacol Res 62, 357-363.
-
(2010)
Pharmacol Res
, vol.62
, pp. 357-363
-
-
Chiba, Y.1
Suzuki, K.2
Uechi, M.3
Kurihara, E.4
Goto, K.5
Sakai, H.6
Misawa, M.7
-
66
-
-
77958014002
-
Sphingosine-1-phosphate-dependent activation of p38 MAPK maintains elevated peripheral resistance in heart failure through increased myogenic vasoconstriction
-
Hoefer J, Azam MA, Kroetsch JT, Leong-Poi H, Momen MA, Voigtlaender-Bolz J, Scherer EQ, Meissner A, Bolz SS, &, Husain M, (2010) Sphingosine-1- phosphate-dependent activation of p38 MAPK maintains elevated peripheral resistance in heart failure through increased myogenic vasoconstriction. Circ Res 107, 923-933.
-
(2010)
Circ Res
, vol.107
, pp. 923-933
-
-
Hoefer, J.1
Azam, M.A.2
Kroetsch, J.T.3
Leong-Poi, H.4
Momen, M.A.5
Voigtlaender-Bolz, J.6
Scherer, E.Q.7
Meissner, A.8
Bolz, S.S.9
Husain, M.10
-
67
-
-
0036499890
-
Sphingosine 1-phosphate evokes calcium signals in C2C12 myoblasts via Edg3 and Edg5 receptors
-
Meacci E, Cencetti F, Formigli L, Squecco R, Donati C, Tiribilli B, Quercioli F, Zecchi Orlandini S, Francini F, &, Bruni P, (2002) Sphingosine 1-phosphate evokes calcium signals in C2C12 myoblasts via Edg3 and Edg5 receptors. Biochem J 362, 349-357.
-
(2002)
Biochem J
, vol.362
, pp. 349-357
-
-
Meacci, E.1
Cencetti, F.2
Formigli, L.3
Squecco, R.4
Donati, C.5
Tiribilli, B.6
Quercioli, F.7
Zecchi Orlandini, S.8
Francini, F.9
Bruni, P.10
-
68
-
-
58149345610
-
Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain
-
Kimura A, Ohmori T, Kashiwakura Y, Ohkawa R, Madoiwa S, Mimuro J, Shimazaki K, Hoshino Y, Yatomi Y, &, Sakata Y, (2008) Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain. Stroke 39, 3411-3417.
-
(2008)
Stroke
, vol.39
, pp. 3411-3417
-
-
Kimura, A.1
Ohmori, T.2
Kashiwakura, Y.3
Ohkawa, R.4
Madoiwa, S.5
Mimuro, J.6
Shimazaki, K.7
Hoshino, Y.8
Yatomi, Y.9
Sakata, Y.10
-
69
-
-
82955177042
-
Frequent spontaneous seizures followed by spatial working memory/anxiety deficits in mice lacking sphingosine 1-phosphate receptor 2
-
Akahoshi N, Ishizaki Y, Yasuda H, Murashima YL, Shinba T, Goto K, Himi T, Chun J, &, Ishii I, (2011) Frequent spontaneous seizures followed by spatial working memory/anxiety deficits in mice lacking sphingosine 1-phosphate receptor 2. Epilepsy Behav 22, 659-665.
-
(2011)
Epilepsy Behav
, vol.22
, pp. 659-665
-
-
Akahoshi, N.1
Ishizaki, Y.2
Yasuda, H.3
Murashima, Y.L.4
Shinba, T.5
Goto, K.6
Himi, T.7
Chun, J.8
Ishii, I.9
-
70
-
-
84862791207
-
S1P2 receptor mediates sphingosine-1-phosphate-induced fibronectin expression via MAPK signaling pathway in mesangial cells under high glucose condition
-
Liu W, Lan T, Xie X, Huang K, Peng J, Huang J, Shen X, Liu P, &, Huang H, (2012) S1P2 receptor mediates sphingosine-1-phosphate-induced fibronectin expression via MAPK signaling pathway in mesangial cells under high glucose condition. Exp Cell Res 318, 936-943.
-
(2012)
Exp Cell Res
, vol.318
, pp. 936-943
-
-
Liu, W.1
Lan, T.2
Xie, X.3
Huang, K.4
Peng, J.5
Huang, J.6
Shen, X.7
Liu, P.8
Huang, H.9
-
71
-
-
84863116009
-
Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury
-
Park SW, Kim M, Brown KM, D'Agati VD, &, Lee HT, (2012) Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury. J Am Soc Nephrol 23, 266-280.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 266-280
-
-
Park, S.W.1
Kim, M.2
Brown, K.M.3
D'Agati, V.D.4
Lee, H.T.5
-
72
-
-
0141679087
-
Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells
-
Yamaguchi H, Kitayama J, Takuwa N, Arikawa K, Inoki I, Takehara K, Nagawa H, &, Takuwa Y, (2003) Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells. Biochem J 374, 715-722.
-
(2003)
Biochem J
, vol.374
, pp. 715-722
-
-
Yamaguchi, H.1
Kitayama, J.2
Takuwa, N.3
Arikawa, K.4
Inoki, I.5
Takehara, K.6
Nagawa, H.7
Takuwa, Y.8
-
73
-
-
0042858413
-
Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity
-
Arikawa K, Takuwa N, Yamaguchi H, Sugimoto N, Kitayama J, Nagawa H, Takehara K, &, Takuwa Y, (2003) Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity. J Biol Chem 278, 32841-32851.
-
(2003)
J Biol Chem
, vol.278
, pp. 32841-32851
-
-
Arikawa, K.1
Takuwa, N.2
Yamaguchi, H.3
Sugimoto, N.4
Kitayama, J.5
Nagawa, H.6
Takehara, K.7
Takuwa, Y.8
-
74
-
-
54249151827
-
Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2
-
Li MH, Sanchez T, Pappalardo A, Lynch KR, Hla T, &, Ferrer F, (2008) Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2. Mol Cancer Res 6, 1649-1656.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1649-1656
-
-
Li, M.H.1
Sanchez, T.2
Pappalardo, A.3
Lynch, K.R.4
Hla, T.5
Ferrer, F.6
-
75
-
-
72249096210
-
Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation
-
Cattoretti G, Mandelbaum J, Lee N, Chaves AH, Mahler AM, Chadburn A, Dalla-Favera R, Pasqualucci L, &, MacLennan AJ, (2009) Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation. Cancer Res 69, 8686-8692.
-
(2009)
Cancer Res
, vol.69
, pp. 8686-8692
-
-
Cattoretti, G.1
Mandelbaum, J.2
Lee, N.3
Chaves, A.H.4
Mahler, A.M.5
Chadburn, A.6
Dalla-Favera, R.7
Pasqualucci, L.8
MacLennan, A.J.9
-
76
-
-
0034614621
-
Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5
-
An S, Zheng Y, &, Bleu T, (2000) Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5. J Biol Chem 275, 288-296.
-
(2000)
J Biol Chem
, vol.275
, pp. 288-296
-
-
An, S.1
Zheng, Y.2
Bleu, T.3
-
77
-
-
79957980683
-
Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A
-
Salas A, Ponnusamy S, Senkal CE, Meyers-Needham M, Selvam SP, Saddoughi SA, Apohan E, Sentelle RD, Smith C, Gault CR, et al,. (2011) Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A. Blood 117, 5941-5952.
-
(2011)
Blood
, vol.117
, pp. 5941-5952
-
-
Salas, A.1
Ponnusamy, S.2
Senkal, C.E.3
Meyers-Needham, M.4
Selvam, S.P.5
Saddoughi, S.A.6
Apohan, E.7
Sentelle, R.D.8
Smith, C.9
Gault, C.R.10
-
78
-
-
84864797320
-
Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis
-
Ponnusamy S, Selvam SP, Mehrotra S, Kawamori T, Snider AJ, Obeid LM, Shao Y, Sabbadini R, &, Ogretmen B, (2012) Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis. EMBO Mol Med 4, 761-775.
-
(2012)
EMBO Mol Med
, vol.4
, pp. 761-775
-
-
Ponnusamy, S.1
Selvam, S.P.2
Mehrotra, S.3
Kawamori, T.4
Snider, A.J.5
Obeid, L.M.6
Shao, Y.7
Sabbadini, R.8
Ogretmen, B.9
-
79
-
-
84881163924
-
Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation
-
doi: 10.1096/fj.13-228460
-
Orr Gandy KA, Adada M, Canals D, Carroll B, Roddy P, Hannun YA, &, Obeid LM, (2013) Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation. FASEB J, doi: 10.1096/fj.13-228460.
-
(2013)
FASEB J
-
-
Orr Gandy, K.A.1
Adada, M.2
Canals, D.3
Carroll, B.4
Roddy, P.5
Hannun, Y.A.6
Obeid, L.M.7
-
80
-
-
46949104885
-
'Inside-out' signaling of sphingosine-1-phosphate: Therapeutic targets
-
Takabe K, Paugh SW, Milstien S, &, Spiegel S, (2008) 'Inside-out' signaling of sphingosine-1-phosphate: therapeutic targets. Pharmacol Rev 60, 181-195.
-
(2008)
Pharmacol Rev
, vol.60
, pp. 181-195
-
-
Takabe, K.1
Paugh, S.W.2
Milstien, S.3
Spiegel, S.4
-
81
-
-
84865987259
-
Selectivity and specificity of sphingosine-1-phosphate receptor ligands: Caveats and critical thinking in characterizing receptor-mediated effects
-
Salomone S, &, Waeber C, (2011) Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects. Front Pharmacol 2, 9.
-
(2011)
Front Pharmacol
, vol.2
, pp. 9
-
-
Salomone, S.1
Waeber, C.2
-
82
-
-
78149277336
-
Sphingosine 1-phosphate receptor 4 uses HER2 (ERBB2) to regulate extracellular signal regulated kinase-1/2 in MDA-MB-453 breast cancer cells
-
Long JS, Fujiwara Y, Edwards J, Tannahill CL, Tigyi G, Pyne S, &, Pyne NJ, (2010) Sphingosine 1-phosphate receptor 4 uses HER2 (ERBB2) to regulate extracellular signal regulated kinase-1/2 in MDA-MB-453 breast cancer cells. J Biol Chem 285, 35957-35966.
-
(2010)
J Biol Chem
, vol.285
, pp. 35957-35966
-
-
Long, J.S.1
Fujiwara, Y.2
Edwards, J.3
Tannahill, C.L.4
Tigyi, G.5
Pyne, S.6
Pyne, N.J.7
-
83
-
-
84863142308
-
High throughput screening for S1P receptor agonists and antagonists, S1P2 agonist
-
The Scripps Research Institute Molecular Screening Center, La Jolla, CA
-
Rosen H, (2011) High throughput screening for S1P receptor agonists and antagonists, S1P2 agonist. The Scripps Molecular Screening Center Probe Report. The Scripps Research Institute Molecular Screening Center, La Jolla, CA.
-
(2011)
The Scripps Molecular Screening Center Probe Report
-
-
Rosen, H.1
-
84
-
-
52949108813
-
The alliance of sphingosine-1-phosphate and its receptors in immunity
-
Rivera J, Proia RL, &, Olivera A, (2008) The alliance of sphingosine-1-phosphate and its receptors in immunity. Nat Rev Immunol 8, 753-763.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 753-763
-
-
Rivera, J.1
Proia, R.L.2
Olivera, A.3
-
85
-
-
0036905055
-
Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells
-
Graeler M, &, Goetzl EJ, (2002) Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells. FASEB J 16, 1874-1878.
-
(2002)
FASEB J
, vol.16
, pp. 1874-1878
-
-
Graeler, M.1
Goetzl, E.J.2
-
86
-
-
36248966560
-
Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor
-
Walzer T, Chiossone L, Chaix J, Calver A, Carozzo C, Garrigue-Antar L, Jacques Y, Baratin M, Tomasello E, &, Vivier E, (2007) Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor. Nat Immunol 8, 1337-1344.
-
(2007)
Nat Immunol
, vol.8
, pp. 1337-1344
-
-
Walzer, T.1
Chiossone, L.2
Chaix, J.3
Calver, A.4
Carozzo, C.5
Garrigue-Antar, L.6
Jacques, Y.7
Baratin, M.8
Tomasello, E.9
Vivier, E.10
-
87
-
-
0033783522
-
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
-
Liu Y, Wada R, Yamashita T, Mi Y, Deng CX, Hobson JP, Rosenfeldt HM, Nava VE, Chae SS, Lee MJ, et al,. (2000) Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J Clin Invest 106, 951-961.
-
(2000)
J Clin Invest
, vol.106
, pp. 951-961
-
-
Liu, Y.1
Wada, R.2
Yamashita, T.3
Mi, Y.4
Deng, C.X.5
Hobson, J.P.6
Rosenfeldt, H.M.7
Nava, V.E.8
Chae, S.S.9
Lee, M.J.10
-
88
-
-
0034887535
-
An essential role for the H218/AGR16/Edg-5/LP(B2) sphingosine 1-phosphate receptor in neuronal excitability
-
MacLennan AJ, Carney PR, Zhu WJ, Chaves AH, Garcia J, Grimes JR, Anderson KJ, Roper SN, &, Lee N, (2001) An essential role for the H218/AGR16/Edg-5/LP(B2) sphingosine 1-phosphate receptor in neuronal excitability. Eur J Neurosci 14, 203-209.
-
(2001)
Eur J Neurosci
, vol.14
, pp. 203-209
-
-
MacLennan, A.J.1
Carney, P.R.2
Zhu, W.J.3
Chaves, A.H.4
Garcia, J.5
Grimes, J.R.6
Anderson, K.J.7
Roper, S.N.8
Lee, N.9
-
89
-
-
33846135087
-
Vascular dysfunction in S1P2 sphingosine 1-phosphate receptor knockout mice
-
Lorenz JN, Arend LJ, Robitz R, Paul RJ, &, MacLennan AJ, (2007) Vascular dysfunction in S1P2 sphingosine 1-phosphate receptor knockout mice. Am J Physiol 292, R440-R446.
-
(2007)
Am J Physiol
, vol.292
-
-
Lorenz, J.N.1
Arend, L.J.2
Robitz, R.3
Paul, R.J.4
MacLennan, A.J.5
-
90
-
-
34249845679
-
Deafness and stria vascularis defects in S1P2 receptor-null mice
-
Kono M, Belyantseva IA, Skoura A, Frolenkov GI, Starost MF, Dreier JL, Lidington D, Bolz SS, Friedman TB, Hla T, et al,. (2007) Deafness and stria vascularis defects in S1P2 receptor-null mice. J Biol Chem 282, 10690-10696.
-
(2007)
J Biol Chem
, vol.282
, pp. 10690-10696
-
-
Kono, M.1
Belyantseva, I.A.2
Skoura, A.3
Frolenkov, G.I.4
Starost, M.F.5
Dreier, J.L.6
Lidington, D.7
Bolz, S.S.8
Friedman, T.B.9
Hla, T.10
-
91
-
-
0035823477
-
Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3
-
Ishii I, Friedman B, Ye X, Kawamura S, McGiffert C, Contos JJ, Kingsbury MA, Zhang G, Brown JH, &, Chun J, (2001) Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3. J Biol Chem 276, 33697-33704.
-
(2001)
J Biol Chem
, vol.276
, pp. 33697-33704
-
-
Ishii, I.1
Friedman, B.2
Ye, X.3
Kawamura, S.4
McGiffert, C.5
Contos, J.J.6
Kingsbury, M.A.7
Zhang, G.8
Brown, J.H.9
Chun, J.10
-
92
-
-
78649740029
-
Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4
-
Golfier S, Kondo S, Schulze T, Takeuchi T, Vassileva G, Achtman AH, Graler MH, Abbondanzo SJ, Wiekowski M, Kremmer E, et al,. (2010) Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4. FASEB J 24, 4701-4710.
-
(2010)
FASEB J
, vol.24
, pp. 4701-4710
-
-
Golfier, S.1
Kondo, S.2
Schulze, T.3
Takeuchi, T.4
Vassileva, G.5
Achtman, A.H.6
Graler, M.H.7
Abbondanzo, S.J.8
Wiekowski, M.9
Kremmer, E.10
-
93
-
-
84879495133
-
S1PR5 is pivotal for the homeostasis of patrolling monocytes
-
doi: 10.1002/eji.201343312
-
Debien E, Mayol K, Biajoux V, Daussy C, De Aguero MG, Taillardet M, Dagany N, Brinza L, Henry T, Dubois B, et al,. (2013) S1PR5 is pivotal for the homeostasis of patrolling monocytes. Eur J Immunol, doi: 10.1002/eji.201343312.
-
(2013)
Eur J Immunol
-
-
Debien, E.1
Mayol, K.2
Biajoux, V.3
Daussy, C.4
De Aguero, M.G.5
Taillardet, M.6
Dagany, N.7
Brinza, L.8
Henry, T.9
Dubois, B.10
|