-
1
-
-
0032954241
-
Localization of VEGF-B in the mouse embryo suggests a paracrine role of the growth factor in the developing vasculature
-
Aase K, Lymboussaki A, Kaipainen A, Olofsson B, Alitalo K, Eriksson U. Localization of VEGF-B in the mouse embryo suggests a paracrine role of the growth factor in the developing vasculature. Dev Dyn 215: 12-25, 1999.
-
(1999)
Dev Dyn
, vol.215
, pp. 12-25
-
-
Aase, K.1
Lymboussaki, A.2
Kaipainen, A.3
Olofsson, B.4
Alitalo, K.5
Eriksson, U.6
-
2
-
-
0035902538
-
Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect
-
Aase K, von Euler G, Li X, Ponten A, Thoren P, Cao R, Cao Y, Olofsson B, Gebre-Medhin S, Pekny M, Alitalo K, Betsholtz C, Eriksson U. Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect. Circulation 104: 358-364, 2001.
-
(2001)
Circulation
, vol.104
, pp. 358-364
-
-
Aase, K.1
von Euler, G.2
Li, X.3
Ponten, A.4
Thoren, P.5
Cao, R.6
Cao, Y.7
Olofsson, B.8
Gebre-Medhin, S.9
Pekny, M.10
Alitalo, K.11
Betsholtz, C.12
Eriksson, U.13
-
3
-
-
79961031858
-
Placental growth factor regulates cardiac adaptation and hypertrophy through a paracrine mechanism
-
Accornero F, van Berlo JH, Benard MJ, Lorenz JN, Carmeliet P, Molkentin JD. Placental growth factor regulates cardiac adaptation and hypertrophy through a paracrine mechanism. Circ Res 109: 272-280, 2011.
-
(2011)
Circ Res
, vol.109
, pp. 272-280
-
-
Accornero, F.1
van Berlo, J.H.2
Benard, M.J.3
Lorenz, J.N.4
Carmeliet, P.5
Molkentin, J.D.6
-
4
-
-
0037093078
-
Placental growth factor is a survival factor for tumor endothelial cells and macrophages
-
Adini A, Kornaga T, Firoozbakht F, Benjamin LE. Placental growth factor is a survival factor for tumor endothelial cells and macrophages. Cancer Res 62: 2749-2752, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 2749-2752
-
-
Adini, A.1
Kornaga, T.2
Firoozbakht, F.3
Benjamin, L.E.4
-
5
-
-
78649655419
-
Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis
-
Albrecht I, Kopfstein L, Strittmatter K, Schomber T, Falkevall A, Hagberg CE, Lorentz P, Jeltsch M, Alitalo K, Eriksson U, Christofori G, Pietras K. Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis. PLoS One 5: e14109, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Albrecht, I.1
Kopfstein, L.2
Strittmatter, K.3
Schomber, T.4
Falkevall, A.5
Hagberg, C.E.6
Lorentz, P.7
Jeltsch, M.8
Alitalo, K.9
Eriksson, U.10
Christofori, G.11
Pietras, K.12
-
6
-
-
0028803509
-
Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity
-
Alon T, Hemo I, Itin A, Pe'er J, Stone J, Keshet E. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med 1: 1024-1028, 1995.
-
(1995)
Nat Med
, vol.1
, pp. 1024-1028
-
-
Alon, T.1
Hemo, I.2
Itin, A.3
Pe'er, J.4
Stone, J.5
Keshet, E.6
-
7
-
-
84880863720
-
The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands
-
Anisimov A, Leppänen VM, Tvorogov D, Zarkada G, Jeltsch M, Holopainen T, Kaijalainen S, Alitalo K. The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands. Sci Signal 6: ra52, 2013.
-
(2013)
Sci Signal
, vol.6
-
-
Anisimov, A.1
Leppänen, V.M.2
Tvorogov, D.3
Zarkada, G.4
Jeltsch, M.5
Holopainen, T.6
Kaijalainen, S.7
Alitalo, K.8
-
8
-
-
39749140405
-
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha
-
Arany Z, Foo SY, Ma Y, Ruas JL, Bommi-Reddy A, Girnun G, Cooper M, Laznik D, Chinsomboon J, Rangwala SM, Baek KH, Rosenzweig A, Spiegelman BM. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature 451: 1008-1012, 2008.
-
(2008)
Nature
, vol.451
, pp. 1008-1012
-
-
Arany, Z.1
Foo, S.Y.2
Ma, Y.3
Ruas, J.L.4
Bommi-Reddy, A.5
Girnun, G.6
Cooper, M.7
Laznik, D.8
Chinsomboon, J.9
Rangwala, S.M.10
Baek, K.H.11
Rosenzweig, A.12
Spiegelman, B.M.13
-
9
-
-
0037703184
-
Role of PlGF in the intra-and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
-
Autiero M, Waltenberger J, Communi D, Kranz A, Moons L, Lambrechts D, Kroll J, Plaisance S, De Mol M, Bono F, Kliche S, Fellbrich G, Ballmer-Hofer K, Maglione D, Mayr-Beyrle U, Dewerchin M, Dombrowski S, Stanimirovic D, Van Hummelen P, Dehio C, Hicklin DJ, Persico G, Herbert JM, Communi D, Shibuya M, Collen D, Conway EM, Carmeliet P. Role of PlGF in the intra-and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med 9: 936-943, 2003.
-
(2003)
Nat Med
, vol.9
, pp. 936-943
-
-
Autiero, M.1
Waltenberger, J.2
Communi, D.3
Kranz, A.4
Moons, L.5
Lambrechts, D.6
Kroll, J.7
Plaisance, S.8
De Mol, M.9
Bono, F.10
Kliche, S.11
Fellbrich, G.12
Ballmer-Hofer, K.13
Maglione, D.14
Mayr-Beyrle, U.15
Dewerchin, M.16
Dombrowski, S.17
Stanimirovic, D.18
Van Hummelen, P.19
Dehio, C.20
Hicklin, D.J.21
Persico, G.22
Herbert, J.M.23
Communi, D.24
Shibuya, M.25
Collen, D.26
Conway, E.M.27
Carmeliet, P.28
more..
-
10
-
-
77950953984
-
PlGF blockade does not inhibit angiogenesis during primary tumor growth
-
Bais C, Wu X, Yao J, Yang S, Crawford Y, McCutcheon K, Tan C, Kolumam G, Vernes JM, Eastham-Anderson J, Haughney P, Kowanetz M, Hagenbeek T, Kasman I, Reslan HB, Ross J, Van Bruggen N, Carano RA, Meng YJ, Hongo JA, Stephan JP, Shibuya M, Ferrara N. PlGF blockade does not inhibit angiogenesis during primary tumor growth. Cell 141: 166-177, 2010.
-
(2010)
Cell
, vol.141
, pp. 166-177
-
-
Bais, C.1
Wu, X.2
Yao, J.3
Yang, S.4
Crawford, Y.5
McCutcheon, K.6
Tan, C.7
Kolumam, G.8
Vernes, J.M.9
Eastham-Anderson, J.10
Haughney, P.11
Kowanetz, M.12
Hagenbeek, T.13
Kasman, I.14
Reslan, H.B.15
Ross, J.16
Van Bruggen, N.17
Carano, R.A.18
Meng, Y.J.19
Hongo, J.A.20
Stephan, J.P.21
Shibuya, M.22
Ferrara, N.23
more..
-
11
-
-
0029867554
-
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
-
Barleon B, Sozzani S, Zhou D, Weich HA, Mantovani A, Marme D. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 87: 3336-3343, 1996.
-
(1996)
Blood
, vol.87
, pp. 3336-3343
-
-
Barleon, B.1
Sozzani, S.2
Zhou, D.3
Weich, H.A.4
Mantovani, A.5
Marme, D.6
-
12
-
-
79751503329
-
Brown adipose tissue activity controls triglyceride clearance
-
Bartelt A, Bruns OT, Reimer R, Hohenberg H, Ittrich H, Peldschus K, Kaul MG, Tromsdorf UI, Weller H, Waurisch C, Eychmuller A, Gordts PL, Rinninger F, Bruegelmann K, Freund B, Nielsen P, Merkel M, Heeren J. Brown adipose tissue activity controls triglyceride clearance. Nat Med 17: 200-205, 2011.
-
(2011)
Nat Med
, vol.17
, pp. 200-205
-
-
Bartelt, A.1
Bruns, O.T.2
Reimer, R.3
Hohenberg, H.4
Ittrich, H.5
Peldschus, K.6
Kaul, M.G.7
Tromsdorf, U.I.8
Weller, H.9
Waurisch, C.10
Eychmuller, A.11
Gordts, P.L.12
Rinninger, F.13
Bruegelmann, K.14
Freund, B.15
Nielsen, P.16
Merkel, M.17
Heeren, J.18
-
13
-
-
27144513291
-
Intracellular pathways triggered by the selective FLT-1-agonist placental growth factor in vascular smooth muscle cells exposed to hypoxia
-
Bellik L, Vinci MC, Filippi S, Ledda F, Parenti A. Intracellular pathways triggered by the selective FLT-1-agonist placental growth factor in vascular smooth muscle cells exposed to hypoxia. Br J Pharmacol 146: 568-575, 2005.
-
(2005)
Br J Pharmacol
, vol.146
, pp. 568-575
-
-
Bellik, L.1
Vinci, M.C.2
Filippi, S.3
Ledda, F.4
Parenti, A.5
-
14
-
-
18844473540
-
Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia
-
Bellomo D, Headrick JP, Silins GU, Paterson CA, Thomas PS, Gartside M, Mould A, Cahill MM, Tonks ID, Grimmond SM, Townson S, Wells C, Little M, Cummings MC, Hayward NK, Kay GF. Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia. Circ Res 86: E29-E35, 2000.
-
(2000)
Circ Res
, vol.86
-
-
Bellomo, D.1
Headrick, J.P.2
Silins, G.U.3
Paterson, C.A.4
Thomas, P.S.5
Gartside, M.6
Mould, A.7
Cahill, M.M.8
Tonks, I.D.9
Grimmond, S.M.10
Townson, S.11
Wells, C.12
Little, M.13
Cummings, M.C.14
Hayward, N.K.15
Kay, G.F.16
-
15
-
-
0032952010
-
Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
-
Benjamin LE, Golijanin D, Itin A, Pode D, Keshet E. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest 103: 159-165, 1999.
-
(1999)
J Clin Invest
, vol.103
, pp. 159-165
-
-
Benjamin, L.E.1
Golijanin, D.2
Itin, A.3
Pode, D.4
Keshet, E.5
-
16
-
-
0030806273
-
Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal
-
Benjamin LE, Keshet E. Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal. Proc Natl Acad Sci USA 94: 8761-8766, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8761-8766
-
-
Benjamin, L.E.1
Keshet, E.2
-
17
-
-
12444317591
-
Angiogenic responses of vascular endothelial growth factors in periadventitial tissue
-
Bhardwaj S, Roy H, Gruchala M, Viita H, Kholova I, Kokina I, Achen MG, Stacker SA, Hedman M, Alitalo K, Yla-Herttuala S. Angiogenic responses of vascular endothelial growth factors in periadventitial tissue. Hum Gene Ther 14: 1451-1462, 2003.
-
(2003)
Hum Gene Ther
, vol.14
, pp. 1451-1462
-
-
Bhardwaj, S.1
Roy, H.2
Gruchala, M.3
Viita, H.4
Kholova, I.5
Kokina, I.6
Achen, M.G.7
Stacker, S.A.8
Hedman, M.9
Alitalo, K.10
Yla-Herttuala, S.11
-
18
-
-
84862776702
-
A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
Bostrom P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Bostrom EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Hojlund K, Gygi SP, Spiegelman BM. A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 481: 463-468, 2012.
-
(2012)
Nature
, vol.481
, pp. 463-468
-
-
Bostrom, P.1
Wu, J.2
Jedrychowski, M.P.3
Korde, A.4
Ye, L.5
Lo, J.C.6
Rasbach, K.A.7
Bostrom, E.A.8
Choi, J.H.9
Long, J.Z.10
Kajimura, S.11
Zingaretti, M.C.12
Vind, B.F.13
Tu, H.14
Cinti, S.15
Hojlund, K.16
Gygi, S.P.17
Spiegelman, B.M.18
-
19
-
-
84857466204
-
Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization
-
Brozzo MS, Bjelic S, Kisko K, Schleier T, Leppänen VM, Alitalo K, Winkler FK, Ballmer-Hofer K. Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization. Blood 119: 1781-1788, 2012.
-
(2012)
Blood
, vol.119
, pp. 1781-1788
-
-
Brozzo, M.S.1
Bjelic, S.2
Kisko, K.3
Schleier, T.4
Leppänen, V.M.5
Alitalo, K.6
Winkler, F.K.7
Ballmer-Hofer, K.8
-
20
-
-
78149281188
-
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
-
Bry M, Kivelä R, Holopainen T, Anisimov A, Tammela T, Soronen J, Silvola J, Saraste A, Jeltsch M, Korpisalo P, Carmeliet P, Lemstrom KB, Shibuya M, Yla-Herttuala S, Alhonen L, Mervaala E, Andersson LC, Knuuti J, Alitalo K. Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation. Circulation 122: 1725-1733, 2010.
-
(2010)
Circulation
, vol.122
, pp. 1725-1733
-
-
Bry, M.1
Kivelä, R.2
Holopainen, T.3
Anisimov, A.4
Tammela, T.5
Soronen, J.6
Silvola, J.7
Saraste, A.8
Jeltsch, M.9
Korpisalo, P.10
Carmeliet, P.11
Lemstrom, K.B.12
Shibuya, M.13
Yla-Herttuala, S.14
Alhonen, L.15
Mervaala, E.16
Andersson, L.C.17
Knuuti, J.18
Alitalo, K.19
-
21
-
-
0029849637
-
In vivo angiogenic activity and hypoxia induction of heterodimers of placenta growth factor/vascular endothelial growth factor
-
Cao Y, Linden P, Shima D, Browne F, Folkman J. In vivo angiogenic activity and hypoxia induction of heterodimers of placenta growth factor/vascular endothelial growth factor. J Clin Invest 98: 2507-2511, 1996.
-
(1996)
J Clin Invest
, vol.98
, pp. 2507-2511
-
-
Cao, Y.1
Linden, P.2
Shima, D.3
Browne, F.4
Folkman, J.5
-
22
-
-
66149098564
-
How form follows functional genomics: Gene expression profiling gastric epithelial cells with a particular discourse on the parietal cell
-
Capoccia BJ, Huh WJ, Mills JC. How form follows functional genomics: gene expression profiling gastric epithelial cells with a particular discourse on the parietal cell. Physiol Genomics 37: 67-78, 2009.
-
(2009)
Physiol Genomics
, vol.37
, pp. 67-78
-
-
Capoccia, B.J.1
Huh, W.J.2
Mills, J.C.3
-
23
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Ebenhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380: 435-439, 1996.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
Fahrig, M.7
Vandenhoeck, A.8
Harpal, K.9
Ebenhardt, C.10
Declercq, C.11
Pawling, J.12
Moons, L.13
Collen, D.14
Risau, W.15
Nagy, A.16
-
24
-
-
19244379078
-
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
-
Carmeliet P, Moons L, Luttun A, Vincenti V, Compernolle V, De Mol M, Wu Y, Bono F, Devy L, Beck H, Scholz D, Acker T, DiPalma T, Dewerchin M, Noel A, Stalmans I, Barra A, Blacher S, Vandendriessche T, Ponten A, Eriksson U, Plate KH, Foidart JM, Schaper W, Charnock-Jones DS, Hicklin DJ, Herbert JM, Collen D, Persico MG. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 7: 575-583, 2001.
-
(2001)
Nat Med
, vol.7
, pp. 575-583
-
-
Carmeliet, P.1
Moons, L.2
Luttun, A.3
Vincenti, V.4
Compernolle, V.5
De Mol, M.6
Wu, Y.7
Bono, F.8
Devy, L.9
Beck, H.10
Scholz, D.11
Acker, T.12
DiPalma, T.13
Dewerchin, M.14
Noel, A.15
Stalmans, I.16
Barra, A.17
Blacher, S.18
Vandendriessche, T.19
Ponten, A.20
Eriksson, U.21
Plate, K.H.22
Foidart, J.M.23
Schaper, W.24
Charnock-Jones, D.S.25
Hicklin, D.J.26
Herbert, J.M.27
Collen, D.28
Persico, M.G.29
more..
-
25
-
-
84871205669
-
Neuropilin-1 identifies a subset of bone marrow Gr1-monocytes that can induce tumor vessel normalization and inhibit tumor growth
-
Carrer A, Moimas S, Zacchigna S, Pattarini L, Zentilin L, Ruozi G, Mano M, Sinigaglia M, Maione F, Serini G, Giraudo E, Bussolino F, Giacca M. Neuropilin-1 identifies a subset of bone marrow Gr1-monocytes that can induce tumor vessel normalization and inhibit tumor growth. Cancer Res 72: 6371-6381, 2012.
-
(2012)
Cancer Res
, vol.72
, pp. 6371-6381
-
-
Carrer, A.1
Moimas, S.2
Zacchigna, S.3
Pattarini, L.4
Zentilin, L.5
Ruozi, G.6
Mano, M.7
Sinigaglia, M.8
Maione, F.9
Serini, G.10
Giraudo, E.11
Bussolino, F.12
Giacca, M.13
-
26
-
-
69949139925
-
Local guidance of emerging vessel sprouts requires soluble Flt-1
-
Chappell JC, Taylor SM, Ferrara N, Bautch VL. Local guidance of emerging vessel sprouts requires soluble Flt-1. Dev Cell 17: 377-386, 2009.
-
(2009)
Dev Cell
, vol.17
, pp. 377-386
-
-
Chappell, J.C.1
Taylor, S.M.2
Ferrara, N.3
Bautch, V.L.4
-
27
-
-
0342872023
-
Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III
-
Chen H, Chedotal A, He Z, Goodman CS, Tessier-Lavigne M. Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III. Neuron 19: 547-559, 1997.
-
(1997)
Neuron
, vol.19
, pp. 547-559
-
-
Chen, H.1
Chedotal, A.2
He, Z.3
Goodman, C.S.4
Tessier-Lavigne, M.5
-
28
-
-
34447502437
-
Upregulation of vascular endothelial growth factor receptors Flt-1 and Flk-1 following acute spinal cord contusion in rats
-
Choi JS, Kim HY, Cha JH, Choi JY, Park SI, Jeong CH, Jeun SS, Lee MY. Upregulation of vascular endothelial growth factor receptors Flt-1 and Flk-1 following acute spinal cord contusion in rats. J Histochem Cytochem 55: 821-830, 2007.
-
(2007)
J Histochem Cytochem
, vol.55
, pp. 821-830
-
-
Choi, J.S.1
Kim, H.Y.2
Cha, J.H.3
Choi, J.Y.4
Park, S.I.5
Jeong, C.H.6
Jeun, S.S.7
Lee, M.Y.8
-
29
-
-
1642297115
-
The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1
-
Christinger HW, Fuh G, de Vos AM, Wiesmann C. The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1. J Biol Chem 279: 10382-10388, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 10382-10388
-
-
Christinger, H.W.1
Fuh, G.2
de Vos, A.M.3
Wiesmann, C.4
-
30
-
-
80054012347
-
Developmental and pathological angiogenesis
-
Chung AS, Ferrara N. Developmental and pathological angiogenesis. Annu Rev Cell Dev Biol 27: 563-584, 2011.
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 563-584
-
-
Chung, A.S.1
Ferrara, N.2
-
31
-
-
0029929716
-
The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis
-
Clauss M, Weich H, Breier G, Knies U, Rockl W, Waltenberger J, Risau W. The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem 271: 17629-17634, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 17629-17634
-
-
Clauss, M.1
Weich, H.2
Breier, G.3
Knies, U.4
Rockl, W.5
Waltenberger, J.6
Risau, W.7
-
32
-
-
84864856289
-
The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis
-
Cudmore MJ, Hewett PW, Ahmad S, Wang KQ, Cai M, Al-Ani B, Fujisawa T, Ma B, Sissaoui S, Ramma W, Miller MR, Newby DE, Gu Y, Barleon B, Weich H, Ahmed A. The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis. Nat Commun 3: 972, 2012.
-
(2012)
Nat Commun
, vol.3
, pp. 972
-
-
Cudmore, M.J.1
Hewett, P.W.2
Ahmad, S.3
Wang, K.Q.4
Cai, M.5
Al-Ani, B.6
Fujisawa, T.7
Ma, B.8
Sissaoui, S.9
Ramma, W.10
Miller, M.R.11
Newby, D.E.12
Gu, Y.13
Barleon, B.14
Weich, H.15
Ahmed, A.16
-
33
-
-
0032488966
-
Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stability
-
Davis-Smyth T, Presta LG, Ferrara N. Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stability. J Biol Chem 273: 3216-3222, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 3216-3222
-
-
Davis-Smyth, T.1
Presta, L.G.2
Ferrara, N.3
-
34
-
-
84856874924
-
The discovery of placenta growth factor and its biological activity
-
De Falco S. The discovery of placenta growth factor and its biological activity. Exp Mol Med 44: 1-9, 2012.
-
(2012)
Exp Mol Med
, vol.44
, pp. 1-9
-
-
De Falco, S.1
-
35
-
-
0026572345
-
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
-
De Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255: 989-991, 1992.
-
(1992)
Science
, vol.255
, pp. 989-991
-
-
De Vries, C.1
Escobedo, J.A.2
Ueno, H.3
Houck, K.4
Ferrara, N.5
Williams, L.T.6
-
36
-
-
77955850711
-
Integrated protein network and microarray analysis to identify potential biomarkers after myocardial infarction
-
Devaux Y, Azuaje F, Vausort M, Yvorra C, Wagner DR. Integrated protein network and microarray analysis to identify potential biomarkers after myocardial infarction. Funct Integr Genomics 10: 329-337, 2010.
-
(2010)
Funct Integr Genomics
, vol.10
, pp. 329-337
-
-
Devaux, Y.1
Azuaje, F.2
Vausort, M.3
Yvorra, C.4
Wagner, D.R.5
-
37
-
-
84859215801
-
Low levels of vascular endothelial growth factor B predict left ventricular remodeling after acute myocardial infarction
-
Devaux Y, Vausort M, Azuaje F, Vaillant M, Lair ML, Gayat E, Lassus J, Ng LL, Kelly D, Wagner DR, Squire IB. Low levels of vascular endothelial growth factor B predict left ventricular remodeling after acute myocardial infarction. J Card Fail 18: 330-337, 2012.
-
(2012)
J Card Fail
, vol.18
, pp. 330-337
-
-
Devaux, Y.1
Vausort, M.2
Azuaje, F.3
Vaillant, M.4
Lair, M.L.5
Gayat, E.6
Lassus, J.7
Ng, L.L.8
Kelly, D.9
Wagner, D.R.10
Squire, I.B.11
-
39
-
-
79955655849
-
Neuronal FLT1 receptor and its selective ligand VEGF-B protect against retrograde degeneration of sensory neurons
-
Dhondt J, Peeraer E, Verheyen A, Nuydens R, Buysschaert I, Poesen K, Van Geyte K, Beerens M, Shibuya M, Haigh JJ, Meert T, Carmeliet P, Lambrechts D. Neuronal FLT1 receptor and its selective ligand VEGF-B protect against retrograde degeneration of sensory neurons. FASEB J 25: 1461-1473, 2011.
-
(2011)
FASEB J
, vol.25
, pp. 1461-1473
-
-
Dhondt, J.1
Peeraer, E.2
Verheyen, A.3
Nuydens, R.4
Buysschaert, I.5
Poesen, K.6
Van Geyte, K.7
Beerens, M.8
Shibuya, M.9
Haigh, J.J.10
Meert, T.11
Carmeliet, P.12
Lambrechts, D.13
-
40
-
-
84863198909
-
Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance
-
Elias I, Franckhauser S, Ferre T, Vila L, Tafuro S, Munoz S, Roca C, Ramos D, Pujol A, Riu E, Ruberte J, Bosch F. Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance. Diabetes 61: 1801-1813, 2012.
-
(2012)
Diabetes
, vol.61
, pp. 1801-1813
-
-
Elias, I.1
Franckhauser, S.2
Ferre, T.3
Vila, L.4
Tafuro, S.5
Munoz, S.6
Roca, C.7
Ramos, D.8
Pujol, A.9
Riu, E.10
Ruberte, J.11
Bosch, F.12
-
41
-
-
8544249876
-
Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia
-
Enholm B, Paavonen K, Ristimaki A, Kumar V, Gunji Y, Klefstrom J, Kivinen L, Laiho M, Olofsson B, Joukov V, Eriksson U, Alitalo K. Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia. Oncogene 14: 2475-2483, 1997.
-
(1997)
Oncogene
, vol.14
, pp. 2475-2483
-
-
Enholm, B.1
Paavonen, K.2
Ristimaki, A.3
Kumar, V.4
Gunji, Y.5
Klefstrom, J.6
Kivinen, L.7
Laiho, M.8
Olofsson, B.9
Joukov, V.10
Eriksson, U.11
Alitalo, K.12
-
42
-
-
79955595805
-
Vascular endothelial growth factor-B is neuroprotective in an in vivo rat model of Parkinson's disease
-
Falk T, Yue X, Zhang S, McCourt AD, Yee BJ, Gonzalez RT, Sherman SJ. Vascular endothelial growth factor-B is neuroprotective in an in vivo rat model of Parkinson's disease. Neurosci Lett 496: 43-47, 2011.
-
(2011)
Neurosci Lett
, vol.496
, pp. 43-47
-
-
Falk, T.1
Yue, X.2
Zhang, S.3
McCourt, A.D.4
Yee, B.J.5
Gonzalez, R.T.6
Sherman, S.J.7
-
43
-
-
74349111035
-
Vascular endothelial growth factor B (VEGF-B) is upregulated and exogenous VEGF-B is neuroprotective in a culture model of Parkinson's disease
-
Falk T, Zhang S, Sherman SJ. Vascular endothelial growth factor B (VEGF-B) is upregulated and exogenous VEGF-B is neuroprotective in a culture model of Parkinson's disease. Mol Neurodegener 4: 49, 2009.
-
(2009)
Mol Neurodegener
, vol.4
, pp. 49
-
-
Falk, T.1
Zhang, S.2
Sherman, S.J.3
-
44
-
-
66349093990
-
Vascular endothelial growth factor
-
Ferrara N. Vascular endothelial growth factor. Arterioscler Thromb Vasc Biol 29: 789-791, 2009.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 789-791
-
-
Ferrara, N.1
-
45
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara N, Carver-Moore K, Chen H, Dowd M, Lu L, O'Shea KS, Powell-Braxton L, Hillan KJ, Moore MW. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380: 439-442, 1996.
-
(1996)
Nature
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O'Shea, K.S.6
Powell-Braxton, L.7
Hillan, K.J.8
Moore, M.W.9
-
46
-
-
0024384470
-
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
-
Ferrara N, Henzel WJ. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 161: 851-858, 1989.
-
(1989)
Biochem Biophys Res Commun
, vol.161
, pp. 851-858
-
-
Ferrara, N.1
Henzel, W.J.2
-
47
-
-
35548982639
-
Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels
-
Fischer C, Jonckx B, Mazzone M, Zacchigna S, Loges S, Pattarini L, Chorianopoulos E, Liesenborghs L, Koch M, De Mol M, Autiero M, Wyns S, Plaisance S, Moons L, van Rooijen N, Giacca M, Stassen JM, Dewerchin M, Collen D, Carmeliet P. Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels. Cell 131: 463-475, 2007.
-
(2007)
Cell
, vol.131
, pp. 463-475
-
-
Fischer, C.1
Jonckx, B.2
Mazzone, M.3
Zacchigna, S.4
Loges, S.5
Pattarini, L.6
Chorianopoulos, E.7
Liesenborghs, L.8
Koch, M.9
De Mol, M.10
Autiero, M.11
Wyns, S.12
Plaisance, S.13
Moons, L.14
van Rooijen, N.15
Giacca, M.16
Stassen, J.M.17
Dewerchin, M.18
Collen, D.19
Carmeliet, P.20
more..
-
48
-
-
0029021660
-
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
Fong GH, Rossant J, Gertsenstein M, Breitman ML. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376: 66-70, 1995.
-
(1995)
Nature
, vol.376
, pp. 66-70
-
-
Fong, G.H.1
Rossant, J.2
Gertsenstein, M.3
Breitman, M.L.4
-
49
-
-
0032764427
-
Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice
-
Fong GH, Zhang L, Bryce DM, Peng J. Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice. Development 126: 3015-3025, 1999.
-
(1999)
Development
, vol.126
, pp. 3015-3025
-
-
Fong, G.H.1
Zhang, L.2
Bryce, D.M.3
Peng, J.4
-
50
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD, Semenza GL. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 16: 4604-4613, 1996.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
Agani, F.4
Leung, S.W.5
Koos, R.D.6
Semenza, G.L.7
-
51
-
-
84859427107
-
PlGF knockout delays brain vessel growth and maturation upon systemic hypoxic challenge
-
Freitas-Andrade M, Carmeliet P, Charlebois C, Stanimirovic DB, Moreno MJ. PlGF knockout delays brain vessel growth and maturation upon systemic hypoxic challenge. J Cereb Blood Flow Metab 32: 663-675, 2012.
-
(2012)
J Cereb Blood Flow Metab
, vol.32
, pp. 663-675
-
-
Freitas-Andrade, M.1
Carmeliet, P.2
Charlebois, C.3
Stanimirovic, D.B.4
Moreno, M.J.5
-
52
-
-
84886411301
-
Comparison of vascular growth factors in the murine brain reveals placenta growth factor as prime candidate for CNS revascularization
-
Gaal EI, Tammela T, Anisimov A, Marbacher S, Honkanen P, Zarkada G, Leppänen VM, Tatlisumak T, Hernesniemi J, Niemela M, Alitalo K. Comparison of vascular growth factors in the murine brain reveals placenta growth factor as prime candidate for CNS revascularization. Blood 122: 658-665, 2013.
-
(2013)
Blood
, vol.122
, pp. 658-665
-
-
Gaal, E.I.1
Tammela, T.2
Anisimov, A.3
Marbacher, S.4
Honkanen, P.5
Zarkada, G.6
Leppänen, V.M.7
Tatlisumak, T.8
Hernesniemi, J.9
Niemela, M.10
Alitalo, K.11
-
53
-
-
57049122852
-
Enhanced angiogenesis in obesity and in response to PPARgamma activators through adipocyte VEGF and ANGPTL4 production
-
Gealekman O, Burkart A, Chouinard M, Nicoloro SM, Straubhaar J, Corvera S. Enhanced angiogenesis in obesity and in response to PPARgamma activators through adipocyte VEGF and ANGPTL4 production. Am J Physiol Endocrinol Metab 295: E1056-E1064, 2008.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
-
-
Gealekman, O.1
Burkart, A.2
Chouinard, M.3
Nicoloro, S.M.4
Straubhaar, J.5
Corvera, S.6
-
54
-
-
0032515047
-
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway
-
Gerber HP, McMurtrey A, Kowalski J, Minhong Y, Keyt BA, Dixit V, Ferrara N. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. J Biol Chem 273: 30336-30343, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 30336-30343
-
-
Gerber, H.P.1
McMurtrey, A.2
Kowalski, J.3
Minhong, Y.4
Keyt, B.A.5
Dixit, V.6
Ferrara, N.7
-
55
-
-
0034674108
-
Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165
-
Gluzman-Poltorak Z, Cohen T, Herzog Y, Neufeld G. Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165. J Biol Chem 275: 18040-18045, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 18040-18045
-
-
Gluzman-Poltorak, Z.1
Cohen, T.2
Herzog, Y.3
Neufeld, G.4
-
56
-
-
19144366076
-
Cloning and characterization of a novel human gene related to vascular endothelial growth factor
-
Grimmond S, Lagercrantz J, Drinkwater C, Silins G, Townson S, Pollock P, Gotley D, Carson E, Rakar S, Nordenskjold M, Ward L, Hayward N, Weber G. Cloning and characterization of a novel human gene related to vascular endothelial growth factor. Genome Res 6: 124-131, 1996.
-
(1996)
Genome Res
, vol.6
, pp. 124-131
-
-
Grimmond, S.1
Lagercrantz, J.2
Drinkwater, C.3
Silins, G.4
Townson, S.5
Pollock, P.6
Gotley, D.7
Carson, E.8
Rakar, S.9
Nordenskjold, M.10
Ward, L.11
Hayward, N.12
Weber, G.13
-
57
-
-
0035300599
-
Vascular endothelial growth factor-B and vascular endothelial growth factor-C expression in renal cell carcinomas: Regulation by the von Hippel-Lindau gene and hypoxia
-
Gunningham SP, Currie MJ, Han C, Turner K, Scott PA, Robinson BA, Harris AL, Fox SB. Vascular endothelial growth factor-B and vascular endothelial growth factor-C expression in renal cell carcinomas: regulation by the von Hippel-Lindau gene and hypoxia. Cancer Res 61: 3206-3211, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 3206-3211
-
-
Gunningham, S.P.1
Currie, M.J.2
Han, C.3
Turner, K.4
Scott, P.A.5
Robinson, B.A.6
Harris, A.L.7
Fox, S.B.8
-
58
-
-
0028899424
-
Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation
-
Guo D, Jia Q, Song HY, Warren RS, Donner DB. Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation. J Biol Chem 270: 6729-6733, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 6729-6733
-
-
Guo, D.1
Jia, Q.2
Song, H.Y.3
Warren, R.S.4
Donner, D.B.5
-
59
-
-
77950865464
-
Vascular endothelial growth factor B controls endothelial fatty acid uptake
-
Hagberg CE, Falkevall A, Wang X, Larsson E, Huusko J, Nilsson I, van Meeteren LA, Samen E, Lu L, Vanwildemeersch M, Klar J, Genove G, Pietras K, Stone-Elander S, Claesson-Welsh L, Yla-Herttuala S, Lindahl P, Eriksson U. Vascular endothelial growth factor B controls endothelial fatty acid uptake. Nature 464: 917-921, 2010.
-
(2010)
Nature
, vol.464
, pp. 917-921
-
-
Hagberg, C.E.1
Falkevall, A.2
Wang, X.3
Larsson, E.4
Huusko, J.5
Nilsson, I.6
van Meeteren, L.A.7
Samen, E.8
Lu, L.9
Vanwildemeersch, M.10
Klar, J.11
Genove, G.12
Pietras, K.13
Stone-Elander, S.14
Claesson-Welsh, L.15
Yla-Herttuala, S.16
Lindahl, P.17
Eriksson, U.18
-
60
-
-
84867672712
-
Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes
-
Hagberg CE, Mehlem A, Falkevall A, Muhl L, Fam BC, Ortsater H, Scotney P, Nyqvist D, Samen E, Lu L, Stone-Elander S, Proietto J, Andrikopoulos S, Sjoholm A, Nash A, Eriksson U. Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes. Nature 490: 426-430, 2012.
-
(2012)
Nature
, vol.490
, pp. 426-430
-
-
Hagberg, C.E.1
Mehlem, A.2
Falkevall, A.3
Muhl, L.4
Fam, B.C.5
Ortsater, H.6
Scotney, P.7
Nyqvist, D.8
Samen, E.9
Lu, L.10
Stone-Elander, S.11
Proietto, J.12
Andrikopoulos, S.13
Sjoholm, A.14
Nash, A.15
Eriksson, U.16
-
61
-
-
0037531794
-
The angiogenic switch for vascular endothelial growth factor (VEGF)-A, VEGF-B, VEGF-C, and VEGF-D in the adenoma-carcinoma sequence during colorectal cancer progression
-
Hanrahan V, Currie MJ, Gunningham SP, Morrin HR, Scott PA, Robinson BA, Fox SB. The angiogenic switch for vascular endothelial growth factor (VEGF)-A, VEGF-B, VEGF-C, and VEGF-D in the adenoma-carcinoma sequence during colorectal cancer progression. J Pathol 200: 183-194, 2003.
-
(2003)
J Pathol
, vol.200
, pp. 183-194
-
-
Hanrahan, V.1
Currie, M.J.2
Gunningham, S.P.3
Morrin, H.R.4
Scott, P.A.5
Robinson, B.A.6
Fox, S.B.7
-
62
-
-
0032482978
-
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
-
Hiratsuka S, Minowa O, Kuno J, Noda T, Shibuya M. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci USA 95: 9349-9354, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9349-9354
-
-
Hiratsuka, S.1
Minowa, O.2
Kuno, J.3
Noda, T.4
Shibuya, M.5
-
63
-
-
84864711123
-
Elevated VEGF receptor-2 abundance contributes to increased angiogenesis in VEGF receptor-1 deficient mice
-
Ho VC, Duan LJ, Cronin C, Liang BT, Fong GH. Elevated VEGF receptor-2 abundance contributes to increased angiogenesis in VEGF receptor-1 deficient mice. Circulation 126: 741-752, 2012.
-
(2012)
Circulation
, vol.126
, pp. 741-752
-
-
Ho, V.C.1
Duan, L.J.2
Cronin, C.3
Liang, B.T.4
Fong, G.H.5
-
64
-
-
14844357211
-
The vascular endothelial growth factor (VEGF) family: Angiogenic factors in health and disease
-
Holmes DI, Zachary I. The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease. Genome Biol 6: 209, 2005.
-
(2005)
Genome Biol
, vol.6
, pp. 209
-
-
Holmes, D.I.1
Zachary, I.2
-
65
-
-
84870589839
-
AAV9-mediated VEGF-B gene transfer improves systolic function in progressive left ventricular hypertrophy
-
Huusko J, Lottonen L, Merentie M, Gurzeler E, Anisimov A, Miyanohara A, Alitalo K, Tavi P, Yla-Herttuala S. AAV9-mediated VEGF-B gene transfer improves systolic function in progressive left ventricular hypertrophy. Mol Ther 20: 2212-2221, 2012.
-
(2012)
Mol Ther
, vol.20
, pp. 2212-2221
-
-
Huusko, J.1
Lottonen, L.2
Merentie, M.3
Gurzeler, E.4
Anisimov, A.5
Miyanohara, A.6
Alitalo, K.7
Tavi, P.8
Yla-Herttuala, S.9
-
66
-
-
77949420545
-
The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice
-
Huusko J, Merentie M, Dijkstra MH, Ryhanen MM, Karvinen H, Rissanen TT, Vanwildemeersch M, Hedman M, Lipponen J, Heinonen SE, Eriksson U, Shibuya M, Yla-Herttuala S. The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice. Cardiovasc Res 86: 122-130, 2010.
-
(2010)
Cardiovasc Res
, vol.86
, pp. 122-130
-
-
Huusko, J.1
Merentie, M.2
Dijkstra, M.H.3
Ryhanen, M.M.4
Karvinen, H.5
Rissanen, T.T.6
Vanwildemeersch, M.7
Hedman, M.8
Lipponen, J.9
Heinonen, S.E.10
Eriksson, U.11
Shibuya, M.12
Yla-Herttuala, S.13
-
67
-
-
77954912465
-
Structural insights into the binding of vascular endothelial growth factor-B by VEGFR-1(D2): Recognition and specificity
-
Iyer S, Darley PI, Acharya KR. Structural insights into the binding of vascular endothelial growth factor-B by VEGFR-1(D2): recognition and specificity. J Biol Chem 285: 23779-23789, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 23779-23789
-
-
Iyer, S.1
Darley, P.I.2
Acharya, K.R.3
-
68
-
-
33646185640
-
Crystal structure of human vascular endothelial growth factor-B: Identification of amino acids important for receptor binding
-
Iyer S, Scotney PD, Nash AD, Ravi Acharya K. Crystal structure of human vascular endothelial growth factor-B: identification of amino acids important for receptor binding. J Mol Biol 359: 76-85, 2006.
-
(2006)
J Mol Biol
, vol.359
, pp. 76-85
-
-
Iyer, S.1
Scotney, P.D.2
Nash, A.D.3
Ravi Acharya, K.4
-
69
-
-
84875843715
-
NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth
-
Jaba IM, Zhuang ZW, Li N, Jiang Y, Martin KA, Sinusas AJ, Papademetris X, Simons M, Sessa WC, Young LH, Tirziu D. NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth. J Clin Invest 123: 1718-1731, 2013.
-
(2013)
J Clin Invest
, vol.123
, pp. 1718-1731
-
-
Jaba, I.M.1
Zhuang, Z.W.2
Li, N.3
Jiang, Y.4
Martin, K.A.5
Sinusas, A.J.6
Papademetris, X.7
Simons, M.8
Sessa, W.C.9
Young, L.H.10
Tirziu, D.11
-
70
-
-
84903560158
-
CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation
-
Feb 19 (Epub ahead of print)
-
Jeltsch M, Jha SK, Tvorogov D, Anisimov A, Leppänen VM, Holopainen T, Kivelä R, Ortega S, Karpanen T, Alitalo K. CCBE1 enhances lymphangiogenesis via ADAMTS3-mediated VEGF-C activation. Circulation 2014 Feb 19 (Epub ahead of print).
-
(2014)
Circulation
-
-
Jeltsch, M.1
Jha, S.K.2
Tvorogov, D.3
Anisimov, A.4
Leppänen, V.M.5
Holopainen, T.6
Kivelä, R.7
Ortega, S.8
Karpanen, T.9
Alitalo, K.10
-
71
-
-
0027428644
-
The related FLT4, FLT1, and KDR receptor tyrosine kinases show distinct expression patterns in human fetal endothelial cells
-
Kaipainen A, Korhonen J, Pajusola K, Aprelikova O, Persico MG, Terman BI, Alitalo K. The related FLT4, FLT1, and KDR receptor tyrosine kinases show distinct expression patterns in human fetal endothelial cells. J Exp Med 178: 2077-2088, 1993.
-
(1993)
J Exp Med
, vol.178
, pp. 2077-2088
-
-
Kaipainen, A.1
Korhonen, J.2
Pajusola, K.3
Aprelikova, O.4
Persico, M.G.5
Terman, B.I.6
Alitalo, K.7
-
72
-
-
55449118233
-
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
-
Karpanen T, Bry M, Ollila HM, Seppanen-Laakso T, Liimatta E, Leskinen H, Kivelä R, Helkamaa T, Merentie M, Jeltsch M, Paavonen K, Andersson LC, Mervaala E, Hassinen IE, Yla-Herttuala S, Oresic M, Alitalo K. Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy. Circ Res 103: 1018-1026, 2008.
-
(2008)
Circ Res
, vol.103
, pp. 1018-1026
-
-
Karpanen, T.1
Bry, M.2
Ollila, H.M.3
Seppanen-Laakso, T.4
Liimatta, E.5
Leskinen, H.6
Kivelä, R.7
Helkamaa, T.8
Merentie, M.9
Jeltsch, M.10
Paavonen, K.11
Andersson, L.C.12
Mervaala, E.13
Hassinen, I.E.14
Yla-Herttuala, S.15
Oresic, M.16
Alitalo, K.17
-
73
-
-
0032707249
-
A requirement for neuropilin-1 in embryonic vessel formation
-
Kawasaki T, Kitsukawa T, Bekku Y, Matsuda Y, Sanbo M, Yagi T, Fujisawa H. A requirement for neuropilin-1 in embryonic vessel formation. Development 126: 4895-4902, 1999.
-
(1999)
Development
, vol.126
, pp. 4895-4902
-
-
Kawasaki, T.1
Kitsukawa, T.2
Bekku, Y.3
Matsuda, Y.4
Sanbo, M.5
Yagi, T.6
Fujisawa, H.7
-
74
-
-
0027421333
-
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
-
Kendall RL, Thomas KA. Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci USA 90: 10705-10709, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10705-10709
-
-
Kendall, R.L.1
Thomas, K.A.2
-
75
-
-
84895734499
-
VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart
-
Kivelä R, Bry M, Robciuc MR, Rasanen M, Taavitsainen M, Silvola JM, Saraste A, Hulmi JJ, Anisimov A, Mayranpaa MI, Lindeman JH, Eklund L, Hellberg S, Hlushchuk R, Zhuang ZW, Simons M, Djonov V, Knuuti J, Mervaala E, Alitalo K. VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. EMBO Mol Med 6: 307-321, 2014.
-
(2014)
EMBO Mol Med
, vol.6
, pp. 307-321
-
-
Kivelä, R.1
Bry, M.2
Robciuc, M.R.3
Rasanen, M.4
Taavitsainen, M.5
Silvola, J.M.6
Saraste, A.7
Hulmi, J.J.8
Anisimov, A.9
Mayranpaa, M.I.10
Lindeman, J.H.11
Eklund, L.12
Hellberg, S.13
Hlushchuk, R.14
Zhuang, Z.W.15
Simons, M.16
Djonov, V.17
Knuuti, J.18
Mervaala, E.19
Alitalo, K.20
more..
-
76
-
-
44149095754
-
Exercise-induced expression of angiogenic growth factors in skeletal muscle and in capillaries of healthy and diabetic mice
-
Kivelä R, Silvennoinen M, Lehti M, Jalava S, Vihko V, Kainulainen H. Exercise-induced expression of angiogenic growth factors in skeletal muscle and in capillaries of healthy and diabetic mice. Cardiovasc Diabetol 7: 13, 2008.
-
(2008)
Cardiovasc Diabetol
, vol.7
, pp. 13
-
-
Kivelä, R.1
Silvennoinen, M.2
Lehti, M.3
Jalava, S.4
Vihko, V.5
Kainulainen, H.6
-
77
-
-
84880742193
-
Signal transduction by vascular endothelial growth factor receptors
-
Koch S, Claesson-Welsh L. Signal transduction by vascular endothelial growth factor receptors. Cold Spring Harb Persect Med 2: a006502, 2012.
-
(2012)
Cold Spring Harb Persect Med
, vol.2
-
-
Koch, S.1
Claesson-Welsh, L.2
-
78
-
-
0030829388
-
Neuropilin is a semaphorin III receptor
-
Kolodkin AL, Levengood DV, Rowe EG, Tai YT, Giger RJ, Ginty DD. Neuropilin is a semaphorin III receptor. Cell 90: 753-762, 1997.
-
(1997)
Cell
, vol.90
, pp. 753-762
-
-
Kolodkin, A.L.1
Levengood, D.V.2
Rowe, E.G.3
Tai, Y.T.4
Giger, R.J.5
Ginty, D.D.6
-
79
-
-
79955555428
-
Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo
-
Krueger J, Liu D, Scholz K, Zimmer A, Shi Y, Klein C, Siekmann A, Schulte-Merker S, Cudmore M, Ahmed A, le Noble F. Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo. Development 138: 2111-2120, 2011.
-
(2011)
Development
, vol.138
, pp. 2111-2120
-
-
Krueger, J.1
Liu, D.2
Scholz, K.3
Zimmer, A.4
Shi, Y.5
Klein, C.6
Siekmann, A.7
Schulte-Merker, S.8
Cudmore, M.9
Ahmed, A.10
le Noble, F.11
-
80
-
-
0032537456
-
A comparative study of the expression patterns for vegf, vegf-b/vrf and vegf-c in the developing and adult mouse
-
Lagercrantz J, Farnebo F, Larsson C, Tvrdik T, Weber G, Piehl F. A comparative study of the expression patterns for vegf, vegf-b/vrf and vegf-c in the developing and adult mouse. Biochim Biophys Acta 1398: 157-163, 1998.
-
(1998)
Biochim Biophys Acta
, vol.1398
, pp. 157-163
-
-
Lagercrantz, J.1
Farnebo, F.2
Larsson, C.3
Tvrdik, T.4
Weber, G.5
Piehl, F.6
-
81
-
-
61949383594
-
Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1-and neuropilin receptor-1-dependent mechanisms
-
Lahteenvuo JE, Lahteenvuo MT, Kivelä A, Rosenlew C, Falkevall A, Klar J, Heikura T, Rissanen TT, Vahakangas E, Korpisalo P, Enholm B, Carmeliet P, Alitalo K, Eriksson U, Yla-Herttuala S. Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1-and neuropilin receptor-1-dependent mechanisms. Circulation 119: 845-856, 2009.
-
(2009)
Circulation
, vol.119
, pp. 845-856
-
-
Lahteenvuo, J.E.1
Lahteenvuo, M.T.2
Kivelä, A.3
Rosenlew, C.4
Falkevall, A.5
Klar, J.6
Heikura, T.7
Rissanen, T.T.8
Vahakangas, E.9
Korpisalo, P.10
Enholm, B.11
Carmeliet, P.12
Alitalo, K.13
Eriksson, U.14
Yla-Herttuala, S.15
-
82
-
-
0032556950
-
Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1
-
Landgren E, Schiller P, Cao Y, Claesson-Welsh L. Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1. Oncogene 16: 359-367, 1998.
-
(1998)
Oncogene
, vol.16
, pp. 359-367
-
-
Landgren, E.1
Schiller, P.2
Cao, Y.3
Claesson-Welsh, L.4
-
83
-
-
77953896432
-
Cell signaling by receptor tyrosine kinases
-
Lemmon MA, Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 141: 1117-1134, 2010.
-
(2010)
Cell
, vol.141
, pp. 1117-1134
-
-
Lemmon, M.A.1
Schlessinger, J.2
-
84
-
-
77249148863
-
Structural determinants of growth factor binding and specificity by VEGF receptor 2
-
Leppänen VM, Prota AE, Jeltsch M, Anisimov A, Kalkkinen N, Strandin T, Lankinen H, Goldman A, Ballmer-Hofer K, Alitalo K. Structural determinants of growth factor binding and specificity by VEGF receptor 2. Proc Natl Acad Sci USA 107: 2425-2430, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2425-2430
-
-
Leppänen, V.M.1
Prota, A.E.2
Jeltsch, M.3
Anisimov, A.4
Kalkkinen, N.5
Strandin, T.6
Lankinen, H.7
Goldman, A.8
Ballmer-Hofer, K.9
Alitalo, K.10
-
85
-
-
84881398446
-
Structural and mechanistic insights into VEGFR-3 ligand binding and activation
-
Leppänen VM, Tvorogov D, Kisko K, Prota AE, Jeltsch M, Anisimov A, Markovic-Mueller S, Stuttfeld E, Goldie KN, Ballmer-Hofer K, Alitalo K. Structural and mechanistic insights into VEGFR-3 ligand binding and activation. Proc Natl Acad Sci USA 110: 12960-12965, 2013.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 12960-12965
-
-
Leppänen, V.M.1
Tvorogov, D.2
Kisko, K.3
Prota, A.E.4
Jeltsch, M.5
Anisimov, A.6
Markovic-Mueller, S.7
Stuttfeld, E.8
Goldie, K.N.9
Ballmer-Hofer, K.10
Alitalo, K.11
-
86
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246: 1306-1309, 1989.
-
(1989)
Science
, vol.246
, pp. 1306-1309
-
-
Leung, D.W.1
Cachianes, G.2
Kuang, W.J.3
Goeddel, D.V.4
Ferrara, N.5
-
87
-
-
10744227199
-
Circulating angiogenic factors and the risk of preeclampsia
-
Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 350: 672-683, 2004.
-
(2004)
N Engl J Med
, vol.350
, pp. 672-683
-
-
Levine, R.J.1
Maynard, S.E.2
Qian, C.3
Lim, K.H.4
England, L.J.5
Yu, K.F.6
Schisterman, E.F.7
Thadhani, R.8
Sachs, B.P.9
Epstein, F.H.10
Sibai, B.M.11
Sukhatme, V.P.12
Karumanchi, S.A.13
-
88
-
-
51649123294
-
Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium
-
Li X, Tjwa M, Van Hove I, Enholm B, Neven E, Paavonen K, Jeltsch M, Juan TD, Sievers RE, Chorianopoulos E, Wada H, Vanwildemeersch M, Noel A, Foidart JM, Springer ML, von Degenfeld G, Dewerchin M, Blau HM, Alitalo K, Eriksson U, Carmeliet P, Moons L. Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium. Arterioscler Thromb Vasc Biol 28: 1614-1620, 2008.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1614-1620
-
-
Li, X.1
Tjwa, M.2
Van Hove, I.3
Enholm, B.4
Neven, E.5
Paavonen, K.6
Jeltsch, M.7
Juan, T.D.8
Sievers, R.E.9
Chorianopoulos, E.10
Wada, H.11
Vanwildemeersch, M.12
Noel, A.13
Foidart, J.M.14
Springer, M.L.15
von Degenfeld, G.16
Dewerchin, M.17
Blau, H.M.18
Alitalo, K.19
Eriksson, U.20
Carmeliet, P.21
Moons, L.22
more..
-
89
-
-
40549090548
-
VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats
-
Li Y, Zhang F, Nagai N, Tang Z, Zhang S, Scotney P, Lennartsson J, Zhu C, Qu Y, Fang C, Hua J, Matsuo O, Fong GH, Ding H, Cao Y, Becker KG, Nash A, Heldin CH, Li X. VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats. J Clin Invest 118: 913-923, 2008.
-
(2008)
J Clin Invest
, vol.118
, pp. 913-923
-
-
Li, Y.1
Zhang, F.2
Nagai, N.3
Tang, Z.4
Zhang, S.5
Scotney, P.6
Lennartsson, J.7
Zhu, C.8
Qu, Y.9
Fang, C.10
Hua, J.11
Matsuo, O.12
Fong, G.H.13
Ding, H.14
Cao, Y.15
Becker, K.G.16
Nash, A.17
Heldin, C.H.18
Li, X.19
-
90
-
-
33750858405
-
Impaired adipose tissue development in mice with inactivation of placental growth factor function
-
Lijnen HR, Christiaens V, Scroyen I, Voros G, Tjwa M, Carmeliet P, Collen D. Impaired adipose tissue development in mice with inactivation of placental growth factor function. Diabetes 55: 2698-2704, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 2698-2704
-
-
Lijnen, H.R.1
Christiaens, V.2
Scroyen, I.3
Voros, G.4
Tjwa, M.5
Carmeliet, P.6
Collen, D.7
-
91
-
-
84862740201
-
Resistance to obesity by repression of VEGF gene expression through induction of brown-like adipocyte differentiation
-
Lu X, Ji Y, Zhang L, Zhang Y, Zhang S, An Y, Liu P, Zheng Y. Resistance to obesity by repression of VEGF gene expression through induction of brown-like adipocyte differentiation. Endocrinology 153: 3123-3132, 2012.
-
(2012)
Endocrinology
, vol.153
, pp. 3123-3132
-
-
Lu, X.1
Ji, Y.2
Zhang, L.3
Zhang, Y.4
Zhang, S.5
An, Y.6
Liu, P.7
Zheng, Y.8
-
92
-
-
0036344495
-
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
-
Luttun A, Tjwa M, Moons L, Wu Y, Angelillo-Scherrer A, Liao F, Nagy JA, Hooper A, Priller J, De Klerck B, Compernolle V, Daci E, Bohlen P, Dewerchin M, Herbert JM, Fava R, Matthys P, Carmeliet G, Collen D, Dvorak HF, Hicklin DJ, Carmeliet P. Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat Med 8: 831-840, 2002.
-
(2002)
Nat Med
, vol.8
, pp. 831-840
-
-
Luttun, A.1
Tjwa, M.2
Moons, L.3
Wu, Y.4
Angelillo-Scherrer, A.5
Liao, F.6
Nagy, J.A.7
Hooper, A.8
Priller, J.9
De Klerck, B.10
Compernolle, V.11
Daci, E.12
Bohlen, P.13
Dewerchin, M.14
Herbert, J.M.15
Fava, R.16
Matthys, P.17
Carmeliet, G.18
Collen, D.19
Dvorak, H.F.20
Hicklin, D.J.21
Carmeliet, P.22
more..
-
93
-
-
0033597813
-
Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1
-
Makinen T, Olofsson B, Karpanen T, Hellman U, Soker S, Klagsbrun M, Eriksson U, Alitalo K. Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1. J Biol Chem 274: 21217-21222, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 21217-21222
-
-
Makinen, T.1
Olofsson, B.2
Karpanen, T.3
Hellman, U.4
Soker, S.5
Klagsbrun, M.6
Eriksson, U.7
Alitalo, K.8
-
94
-
-
84878785347
-
Immunological goings-on in visceral adipose tissue
-
Mathis D. Immunological goings-on in visceral adipose tissue. Cell Metab 17: 851-859, 2013.
-
(2013)
Cell Metab
, vol.17
, pp. 851-859
-
-
Mathis, D.1
-
95
-
-
0032575576
-
Neuropilin-1 is a placenta growth factor-2 receptor
-
Migdal M, Huppertz B, Tessler S, Comforti A, Shibuya M, Reich R, Baumann H, Neufeld G. Neuropilin-1 is a placenta growth factor-2 receptor. J Biol Chem 273: 22272-22278, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 22272-22278
-
-
Migdal, M.1
Huppertz, B.2
Tessler, S.3
Comforti, A.4
Shibuya, M.5
Reich, R.6
Baumann, H.7
Neufeld, G.8
-
96
-
-
10744224439
-
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
-
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-640, 2003.
-
(2003)
Cell
, vol.115
, pp. 629-640
-
-
Mootha, V.K.1
Bunkenborg, J.2
Olsen, J.V.3
Hjerrild, M.4
Wisniewski, J.R.5
Stahl, E.6
Bolouri, M.S.7
Ray, H.N.8
Sihag, S.9
Kamal, M.10
Patterson, N.11
Lander, E.S.12
Mann, M.13
-
97
-
-
27744471912
-
Transgenic overexpression of vascular endothelial growth factor-B isoforms by endothelial cells potentiates postnatal vessel growth in vivo and in vitro
-
Mould AW, Greco SA, Cahill MM, Tonks ID, Bellomo D, Patterson C, Zournazi A, Nash A, Scotney P, Hayward NK, Kay GF. Transgenic overexpression of vascular endothelial growth factor-B isoforms by endothelial cells potentiates postnatal vessel growth in vivo and in vitro. Circ Res 97: e60-70, 2005.
-
(2005)
Circ Res
, vol.97
-
-
Mould, A.W.1
Greco, S.A.2
Cahill, M.M.3
Tonks, I.D.4
Bellomo, D.5
Patterson, C.6
Zournazi, A.7
Nash, A.8
Scotney, P.9
Hayward, N.K.10
Kay, G.F.11
-
98
-
-
84878962706
-
Vascular hyperpermeability, angiogenesis, and stroma generation
-
Nagy JA, Dvorak AM, Dvorak HF. Vascular hyperpermeability, angiogenesis, and stroma generation. Cold Spring Harb Perspect Med 2: a006544, 2012.
-
(2012)
Cold Spring Harb Perspect Med
, vol.2
-
-
Nagy, J.A.1
Dvorak, A.M.2
Dvorak, H.F.3
-
99
-
-
0037096168
-
Mice overexpressing placenta growth factor exhibit increased vascularization and vessel permeability
-
Odorisio T, Schietroma C, Zaccaria ML, Cianfarani F, Tiveron C, Tatangelo L, Failla CM, Zambruno G. Mice overexpressing placenta growth factor exhibit increased vascularization and vessel permeability. J Cell Sci 115: 2559-2567, 2002.
-
(2002)
J Cell Sci
, vol.115
, pp. 2559-2567
-
-
Odorisio, T.1
Schietroma, C.2
Zaccaria, M.L.3
Cianfarani, F.4
Tiveron, C.5
Tatangelo, L.6
Failla, C.M.7
Zambruno, G.8
-
100
-
-
13144266696
-
Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells
-
Olofsson B, Korpelainen E, Pepper MS, Mandriota SJ, Aase K, Kumar V, Gunji Y, Jeltsch MM, Shibuya M, Alitalo K, Eriksson U. Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells. Proc Natl Acad Sci USA 95: 11709-11714, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11709-11714
-
-
Olofsson, B.1
Korpelainen, E.2
Pepper, M.S.3
Mandriota, S.J.4
Aase, K.5
Kumar, V.6
Gunji, Y.7
Jeltsch, M.M.8
Shibuya, M.9
Alitalo, K.10
Eriksson, U.11
-
101
-
-
9244227572
-
Vascular endothelial growth factor B, a novel growth factor for endothelial cells
-
Olofsson B, Pajusola K, Kaipainen A, von Euler G, Joukov V, Saksela O, Orpana A, Pettersson RF, Alitalo K, Eriksson U. Vascular endothelial growth factor B, a novel growth factor for endothelial cells. Proc Natl Acad Sci USA 93: 2576-2581, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2576-2581
-
-
Olofsson, B.1
Pajusola, K.2
Kaipainen, A.3
von Euler, G.4
Joukov, V.5
Saksela, O.6
Orpana, A.7
Pettersson, R.F.8
Alitalo, K.9
Eriksson, U.10
-
102
-
-
0029782928
-
Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform
-
Olofsson B, Pajusola K, von Euler G, Chilov D, Alitalo K, Eriksson U. Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform. J Biol Chem 271: 19310-19317, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 19310-19317
-
-
Olofsson, B.1
Pajusola, K.2
von Euler, G.3
Chilov, D.4
Alitalo, K.5
Eriksson, U.6
-
103
-
-
0037438583
-
A critical role of placental growth factor in the induction of inflammation and edema formation
-
Oura H, Bertoncini J, Velasco P, Brown LF, Carmeliet P, Detmar M. A critical role of placental growth factor in the induction of inflammation and edema formation. Blood 101: 560-567, 2003.
-
(2003)
Blood
, vol.101
, pp. 560-567
-
-
Oura, H.1
Bertoncini, J.2
Velasco, P.3
Brown, L.F.4
Carmeliet, P.5
Detmar, M.6
-
104
-
-
0028134936
-
Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR
-
Park JE, Chen HH, Winer J, Houck KA, Ferrara N. Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J Biol Chem 269: 25646-25654, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 25646-25654
-
-
Park, J.E.1
Chen, H.H.2
Winer, J.3
Houck, K.A.4
Ferrara, N.5
-
105
-
-
0033543126
-
Endothelial growth factor receptors in human fetal heart
-
Partanen TA, Makinen T, Arola J, Suda T, Weich HA, Alitalo K. Endothelial growth factor receptors in human fetal heart. Circulation 100: 583-586, 1999.
-
(1999)
Circulation
, vol.100
, pp. 583-586
-
-
Partanen, T.A.1
Makinen, T.2
Arola, J.3
Suda, T.4
Weich, H.A.5
Alitalo, K.6
-
106
-
-
84861058134
-
Cardiac angiogenic imbalance leads to peripartum cardiomyopathy
-
Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs I, del Monte I, Hilfiker-Kleiner D, Karumanchi SA, Avany Z. Cardiac angiogenic imbalance leads to peripartum cardiomyopathy. Nature 485: 333-338, 2012.
-
(2012)
Nature
, vol.485
, pp. 333-338
-
-
Patten, I.S.1
Rana, S.2
Shahul, S.3
Rowe, G.C.4
Jang, C.5
Liu, L.6
Hacker, M.R.7
Rhee, J.S.8
Mitchell, J.9
Mahmood, F.10
Hess, P.11
Farrell, C.12
Koulisis, N.13
Khankin, E.V.14
Burke, S.D.15
Tudorache, I.16
Bauersachs, I.17
del Monte, I.18
Hilfiker-Kleiner, D.19
Karumanchi, S.A.20
Avany, Z.21
more..
-
107
-
-
42449148407
-
Neuropilins: Structure, function and role in disease
-
Pellet-Many C, Frankel P, Jia H, Zachary I. Neuropilins: structure, function and role in disease. Biochem J 411: 211-226, 2008.
-
(2008)
Biochem J
, vol.411
, pp. 211-226
-
-
Pellet-Many, C.1
Frankel, P.2
Jia, H.3
Zachary, I.4
-
108
-
-
77954214321
-
Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy
-
Pepe M, Mamdani M, Zentilin L, Csiszar A, Qanud K, Zacchigna S, Ungvari Z, Puligadda U, Moimas S, Xu X, Edwards JG, Hintze TH, Giacca M, Recchia FA. Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy. Circ Res 106: 1893-1903, 2010.
-
(2010)
Circ Res
, vol.106
, pp. 1893-1903
-
-
Pepe, M.1
Mamdani, M.2
Zentilin, L.3
Csiszar, A.4
Qanud, K.5
Zacchigna, S.6
Ungvari, Z.7
Puligadda, U.8
Moimas, S.9
Xu, X.10
Edwards, J.G.11
Hintze, T.H.12
Giacca, M.13
Recchia, F.A.14
-
109
-
-
0037423858
-
VEGFR-1-selective VEGF homologue PlGF is arteriogenic: Evidence for a monocyte-mediated mechanism
-
Pipp F, Heil M, Issbrucker K, Ziegelhoeffer T, Martin S, van den Heuvel J, Weich H, Fernandez B, Golomb G, Carmeliet P, Schaper W, Clauss M. VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism. Circ Res 92: 378-385, 2003.
-
(2003)
Circ Res
, vol.92
, pp. 378-385
-
-
Pipp, F.1
Heil, M.2
Issbrucker, K.3
Ziegelhoeffer, T.4
Martin, S.5
van den Heuvel, J.6
Weich, H.7
Fernandez, B.8
Golomb, G.9
Carmeliet, P.10
Schaper, W.11
Clauss, M.12
-
110
-
-
54849424014
-
Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration
-
Poesen K, Lambrechts D, Van Damme P, Dhondt J, Bender F, Frank N, Bogaert E, Claes B, Heylen L, Verheyen A, Raes K, Tjwa M, Eriksson U, Shibuya M, Nuydens R, Van Den Bosch L, Meert T, D'Hooge R, Sendtner M, Robberecht W, Carmeliet P. Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration. J Neurosci 28: 10451-10459, 2008.
-
(2008)
J Neurosci
, vol.28
, pp. 10451-10459
-
-
Poesen, K.1
Lambrechts, D.2
Van Damme, P.3
Dhondt, J.4
Bender, F.5
Frank, N.6
Bogaert, E.7
Claes, B.8
Heylen, L.9
Verheyen, A.10
Raes, K.11
Tjwa, M.12
Eriksson, U.13
Shibuya, M.14
Nuydens, R.15
Van Den Bosch, L.16
Meert, T.17
D'Hooge, R.18
Sendtner, M.19
Robberecht, W.20
Carmeliet, P.21
more..
-
111
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: Role of the HIF system
-
Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 9: 677-684, 2003.
-
(2003)
Nat Med
, vol.9
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
112
-
-
0027249239
-
Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
-
Quinn T, Peters K, DeVries C, Ferrara N, Williams L. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci USA 90: 7533-7537, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7533-7537
-
-
Quinn, T.1
Peters, K.2
DeVries, C.3
Ferrara, N.4
Williams, L.5
-
113
-
-
84878547305
-
Clinical characterization and outcomes of preeclampsia with normal angiogenic profile
-
Rana S, Schnettler WT, Powe C, Wenger J, Salahuddin S, Cerdeira AS, Verlohren S, Perschel FH, Arany Z, Lim KH, Thadhani R, Karumanchi SA. Clinical characterization and outcomes of preeclampsia with normal angiogenic profile. Hypertens Pregnancy 32: 189-201, 2013.
-
(2013)
Hypertens Pregnancy
, vol.32
, pp. 189-201
-
-
Rana, S.1
Schnettler, W.T.2
Powe, C.3
Wenger, J.4
Salahuddin, S.5
Cerdeira, A.S.6
Verlohren, S.7
Perschel, F.H.8
Arany, Z.9
Lim, K.H.10
Thadhani, R.11
Karumanchi, S.A.12
-
114
-
-
0030952289
-
Mechanisms of angiogenesis
-
Risau W. Mechanisms of angiogenesis. Nature 386: 671-674, 1997.
-
(1997)
Nature
, vol.386
, pp. 671-674
-
-
Risau, W.1
-
116
-
-
0037714018
-
VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses
-
Rissanen TT, Markkanen JE, Gruchala M, Heikura T, Puranen A, Kettunen MI, Kholova I, Kauppinen RA, Achen MG, Stacker SA, Alitalo K, Yla-Herttuala S. VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses. Circ Res 92: 1098-1106, 2003.
-
(2003)
Circ Res
, vol.92
, pp. 1098-1106
-
-
Rissanen, T.T.1
Markkanen, J.E.2
Gruchala, M.3
Heikura, T.4
Puranen, A.5
Kettunen, M.I.6
Kholova, I.7
Kauppinen, R.A.8
Achen, M.G.9
Stacker, S.A.10
Alitalo, K.11
Yla-Herttuala, S.12
-
117
-
-
33847630758
-
Structure of a VEGFVEGF receptor complex determined by electron microscopy
-
Ruch C, Skiniotis G, Steinmetz MO, Walz T, Ballmer-Hofer K. Structure of a VEGFVEGF receptor complex determined by electron microscopy. Nat Struct Mol Biol 14: 249-250, 2007.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 249-250
-
-
Ruch, C.1
Skiniotis, G.2
Steinmetz, M.O.3
Walz, T.4
Ballmer-Hofer, K.5
-
118
-
-
67649973540
-
Role and therapeutic potential of VEGF in the nervous system
-
Ruiz de Almodovar C, Lambrechts D, Mazzone M, Carmeliet P. Role and therapeutic potential of VEGF in the nervous system. Physiol Rev 89: 607-648, 2009.
-
(2009)
Physiol Rev
, vol.89
, pp. 607-648
-
-
Ruiz de Almodovar, C.1
Lambrechts, D.2
Mazzone, M.3
Carmeliet, P.4
-
120
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Schweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359: 843-848, 1992.
-
(1992)
Nature
, vol.359
, pp. 843-848
-
-
Schweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
121
-
-
0043156081
-
Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor
-
Selvaraj SK, Giri RK, Perelman N, Johnson C, Malik P, Kalra VK. Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor. Blood 102: 1515-1524, 2003.
-
(2003)
Blood
, vol.102
, pp. 1515-1524
-
-
Selvaraj, S.K.1
Giri, R.K.2
Perelman, N.3
Johnson, C.4
Malik, P.5
Kalra, V.K.6
-
122
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219: 983-985, 1983.
-
(1983)
Science
, vol.219
, pp. 983-985
-
-
Senger, D.R.1
Galli, S.J.2
Dvorak, A.M.3
Perruzzi, C.A.4
Harvey, V.S.5
Dvorak, H.F.6
-
123
-
-
78650460365
-
Vascular endothelial growth factor-B gene transfer prevents angiotensin II-induced diastolic dysfunction via proliferation and capillary dilatation in rats
-
Serpi R, Tolonen AM, Huusko J, Rysa J, Tenhunen O, Yla-Herttuala S, Ruskoaho H. Vascular endothelial growth factor-B gene transfer prevents angiotensin II-induced diastolic dysfunction via proliferation and capillary dilatation in rats. Cardiovasc Res 89: 204-213, 2011.
-
(2011)
Cardiovasc Res
, vol.89
, pp. 204-213
-
-
Serpi, R.1
Tolonen, A.M.2
Huusko, J.3
Rysa, J.4
Tenhunen, O.5
Yla-Herttuala, S.6
Ruskoaho, H.7
-
124
-
-
84871633270
-
Vascular endothelial growth factor and its receptor system: Physiological functions in angiogenesis and pathological roles in various diseases
-
Shibuya M. Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases. J Biochem 153: 13-19, 2013.
-
(2013)
J Biochem
, vol.153
, pp. 13-19
-
-
Shibuya, M.1
-
125
-
-
34447310236
-
Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): A dual regulator for angiogenesis
-
Shibuya M. Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis. Angiogenesis 9: 225-231, 2006.
-
(2006)
Angiogenesis
, vol.9
, pp. 225-231
-
-
Shibuya, M.1
-
126
-
-
33344474964
-
Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis
-
Shibuya M, Claesson-Welsh L. Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis. Exp Cell Res 312: 549-560, 2006.
-
(2006)
Exp Cell Res
, vol.312
, pp. 549-560
-
-
Shibuya, M.1
Claesson-Welsh, L.2
-
127
-
-
0025259592
-
Nucleotide sequence and expression of a novel human receptor type tyrosine kinase gene (flt) closely related to the fms family
-
Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A, Matsushime H, Sato M. Nucleotide sequence and expression of a novel human receptor type tyrosine kinase gene (flt) closely related to the fms family. Oncogene 5: 519-524, 1990.
-
(1990)
Oncogene
, vol.5
, pp. 519-524
-
-
Shibuya, M.1
Yamaguchi, S.2
Yamane, A.3
Ikeda, T.4
Tojo, A.5
Matsushime, H.6
Sato, M.7
-
128
-
-
0042490796
-
Vascular endothelial growth factor-B promotes in vivo angiogenesis
-
Silvestre JS, Tamarat R, Ebrahimian TG, Le-Roux A, Clergue M, Emmanuel F, Duriez M, Schwartz B, Branellec D, Levy BI. Vascular endothelial growth factor-B promotes in vivo angiogenesis. Circ Res 93: 114-123, 2003.
-
(2003)
Circ Res
, vol.93
, pp. 114-123
-
-
Silvestre, J.S.1
Tamarat, R.2
Ebrahimian, T.G.3
Le-Roux, A.4
Clergue, M.5
Emmanuel, F.6
Duriez, M.7
Schwartz, B.8
Branellec, D.9
Levy, B.I.10
-
129
-
-
84876548894
-
Both Kdr and Flt1 play a vital role in hypoxia-induced Src-PLD1-PKCgamma-cPLA(2) activation and retinal neovascularization
-
Singh NK, Hansen DE 3rd, Kundumani-Sridharan V, Rao GN. Both Kdr and Flt1 play a vital role in hypoxia-induced Src-PLD1-PKCgamma-cPLA(2) activation and retinal neovascularization. Blood 121: 1911-1923, 2013.
-
(2013)
Blood
, vol.121
, pp. 1911-1923
-
-
Singh, N.K.1
Hansen III, D.E.2
Kundumani-Sridharan, V.3
Rao, G.N.4
-
130
-
-
84874760414
-
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma
-
Snuderl M, Batista A, Kirkpatrick ND, Ruiz de Almodovar C, Riedemann L, Walsh EC, Anolik R, Huang Y, Martin JD, Kamoun W, Knevels E, Schmidt T, Farrar CT, Vakoc BJ, Mohan N, Chung E, Roberge S, Peterson T, Bais C, Zhelyazkova BH, Yip S, Hasselblatt M, Rossig C, Niemeyer E, Ferrara N, Klagsbrun M, Duda DG, Fukumura D, Xu L, Carmeliet P, Jain RK. Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell 152: 1065-1076, 2013.
-
(2013)
Cell
, vol.152
, pp. 1065-1076
-
-
Snuderl, M.1
Batista, A.2
Kirkpatrick, N.D.3
Ruiz de Almodovar, C.4
Riedemann, L.5
Walsh, E.C.6
Anolik, R.7
Huang, Y.8
Martin, J.D.9
Kamoun, W.10
Knevels, E.11
Schmidt, T.12
Farrar, C.T.13
Vakoc, B.J.14
Mohan, N.15
Chung, E.16
Roberge, S.17
Peterson, T.18
Bais, C.19
Zhelyazkova, B.H.20
Yip, S.21
Hasselblatt, M.22
Rossig, C.23
Niemeyer, E.24
Ferrara, N.25
Klagsbrun, M.26
Duda, D.G.27
Fukumura, D.28
Xu, L.29
Carmeliet, P.30
Jain, R.K.31
more..
-
131
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
-
Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92: 735-745, 1998.
-
(1998)
Cell
, vol.92
, pp. 735-745
-
-
Soker, S.1
Takashima, S.2
Miao, H.Q.3
Neufeld, G.4
Klagsbrun, M.5
-
132
-
-
84859615812
-
Dichotomous effects of VEGF-A on adipose tissue dysfunction
-
Sun K, Wernstedt Asterholm I, Kusminski CM, Bueno AC, Wang ZV, Pollard JW, Brekken RA, Scherer PE. Dichotomous effects of VEGF-A on adipose tissue dysfunction. Proc Natl Acad Sci USA 109: 5874-5879, 2012.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 5874-5879
-
-
Sun, K.1
Wernstedt Asterholm, I.2
Kusminski, C.M.3
Bueno, A.C.4
Wang, Z.V.5
Pollard, J.W.6
Brekken, R.A.7
Scherer, P.E.8
-
133
-
-
4944253249
-
Increased severity of cerebral ischemic injury in vascular endothelial growth factor-B-deficient mice
-
Sun Y, Jin K, Childs JT, Xie L, Mao XO, Greenberg DA. Increased severity of cerebral ischemic injury in vascular endothelial growth factor-B-deficient mice. J Cereb Blood Flow Metab 24: 1146-1152, 2004.
-
(2004)
J Cereb Blood Flow Metab
, vol.24
, pp. 1146-1152
-
-
Sun, Y.1
Jin, K.2
Childs, J.T.3
Xie, L.4
Mao, X.O.5
Greenberg, D.A.6
-
134
-
-
30044451865
-
Vascular endothelial growth factor-B (VEGFB) stimulates neurogenesis: Evidence from knockout mice and growth factor administration
-
Sun Y, Jin K, Childs JT, Xie L, Mao XO, Greenberg DA. Vascular endothelial growth factor-B (VEGFB) stimulates neurogenesis: evidence from knockout mice and growth factor administration. Dev Biol 289: 329-335, 2006.
-
(2006)
Dev Biol
, vol.289
, pp. 329-335
-
-
Sun, Y.1
Jin, K.2
Childs, J.T.3
Xie, L.4
Mao, X.O.5
Greenberg, D.A.6
-
135
-
-
82955187865
-
Skeletal muscle-specific expression of PGC-1alpha-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake
-
Tadaishi M, Miura S, Kai Y, Kano Y, Oishi Y, Ezaki O. Skeletal muscle-specific expression of PGC-1alpha-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake. PLoS One 6: e28290, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Tadaishi, M.1
Miura, S.2
Kai, Y.3
Kano, Y.4
Oishi, Y.5
Ezaki, O.6
-
136
-
-
0033118228
-
VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
-
Takahashi T, Ueno H, Shibuya M. VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene 18: 2221-2230, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 2221-2230
-
-
Takahashi, T.1
Ueno, H.2
Shibuya, M.3
-
137
-
-
0030721770
-
Characterization of the extracellular domain in vascular endothelial growth factor receptor-1 (Flt-1 tyrosine kinase)
-
Tanaka K, Yamaguchi S, Sawano A, Shibuya M. Characterization of the extracellular domain in vascular endothelial growth factor receptor-1 (Flt-1 tyrosine kinase). Jpn J Cancer Res 88: 867-876, 1997.
-
(1997)
Jpn J Cancer Res
, vol.88
, pp. 867-876
-
-
Tanaka, K.1
Yamaguchi, S.2
Sawano, A.3
Shibuya, M.4
-
138
-
-
36048999385
-
Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice
-
Tirziu D, Chorianopoulos E, Moodie KL, Palac RT, Zhuang ZW, Tjwa M, Roncal C, Eriksson U, Fu Q, Elfenbein A, Hall AE, Carmeliet P, Moons L, Simons M. Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice. J Clin Invest 117: 3188-3197, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 3188-3197
-
-
Tirziu, D.1
Chorianopoulos, E.2
Moodie, K.L.3
Palac, R.T.4
Zhuang, Z.W.5
Tjwa, M.6
Roncal, C.7
Eriksson, U.8
Fu, Q.9
Elfenbein, A.10
Hall, A.E.11
Carmeliet, P.12
Moons, L.13
Simons, M.14
-
139
-
-
0036841250
-
Role of VEGF family members and receptors in coronary vessel formation
-
Tomanek RJ, Holifield JS, Reiter RS, Sandra A, Lin JJ. Role of VEGF family members and receptors in coronary vessel formation. Dev Dyn 225: 233-240, 2002.
-
(2002)
Dev Dyn
, vol.225
, pp. 233-240
-
-
Tomanek, R.J.1
Holifield, J.S.2
Reiter, R.S.3
Sandra, A.4
Lin, J.J.5
-
140
-
-
33646155950
-
VEGF family members regulate myocardial tubulogenesis and coronary artery formation in the embryo
-
Tomanek RJ, Ishii Y, Holifield JS, Sjogren CL, Hansen HK, Mikawa T. VEGF family members regulate myocardial tubulogenesis and coronary artery formation in the embryo. Circ Res 98: 947-953, 2006.
-
(2006)
Circ Res
, vol.98
, pp. 947-953
-
-
Tomanek, R.J.1
Ishii, Y.2
Holifield, J.S.3
Sjogren, C.L.4
Hansen, H.K.5
Mikawa, T.6
-
141
-
-
56749093847
-
Vascular effects of FGF-2 and VEGF-B in rabbits with bilateral hind limb ischemia
-
Wafai R, Tudor EM, Angus JA, Wright CE. Vascular effects of FGF-2 and VEGF-B in rabbits with bilateral hind limb ischemia. J Vasc Res 46: 45-54, 2009.
-
(2009)
J Vasc Res
, vol.46
, pp. 45-54
-
-
Wafai, R.1
Tudor, E.M.2
Angus, J.A.3
Wright, C.E.4
-
142
-
-
0036063399
-
Vascular endothelial growth factor-B-deficient mice show impaired development of hypoxic pulmonary hypertension
-
Wanstall JC, Gambino A, Jeffery TK, Cahill MM, Bellomo D, Hayward NK, Kay GF. Vascular endothelial growth factor-B-deficient mice show impaired development of hypoxic pulmonary hypertension. Cardiovasc Res 55: 361-368, 2002.
-
(2002)
Cardiovasc Res
, vol.55
, pp. 361-368
-
-
Wanstall, J.C.1
Gambino, A.2
Jeffery, T.K.3
Cahill, M.M.4
Bellomo, D.5
Hayward, N.K.6
Kay, G.F.7
-
143
-
-
0030782410
-
Crystal structure at 1.7 Å resolution of VEGF in complex with domain 2 of the Flt-1 receptor
-
Wiesmann C, Fuh G, Christinger HW, Eigenbrot C, Wells JA, de Vos AM. Crystal structure at 1.7 Å resolution of VEGF in complex with domain 2 of the Flt-1 receptor. Cell 91: 695-704, 1997.
-
(1997)
Cell
, vol.91
, pp. 695-704
-
-
Wiesmann, C.1
Fuh, G.2
Christinger, H.W.3
Eigenbrot, C.4
Wells, J.A.5
de Vos, A.M.6
-
144
-
-
84876913002
-
Brain homeostasis: VEGF receptor 1 and 2-two unequal brothers in mind
-
Wittko-Schneider IM, Schneider FT, Plate KH. Brain homeostasis: VEGF receptor 1 and 2-two unequal brothers in mind. Cell Mol Life Sci 70: 1705-1725, 2013.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 1705-1725
-
-
Wittko-Schneider, I.M.1
Schneider, F.T.2
Plate, K.H.3
-
145
-
-
2642709170
-
Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth
-
Xia P, Aiello LP, Ishii H, Jiang ZY, Park DJ, Robinson GS, Takagi H, Newsome WP, Jirousek MR, King GL. Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth. J Clin Invest 98: 2018-2026, 1996.
-
(1996)
J Clin Invest
, vol.98
, pp. 2018-2026
-
-
Xia, P.1
Aiello, L.P.2
Ishii, H.3
Jiang, Z.Y.4
Park, D.J.5
Robinson, G.S.6
Takagi, H.7
Newsome, W.P.8
Jirousek, M.R.9
King, G.L.10
-
146
-
-
76649105135
-
Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling
-
Yang Y, Xie P, Opatowsky Y, Schlessinger J. Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling. Proc Natl Acad Sci USA 107: 1906-1911, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1906-1911
-
-
Yang, Y.1
Xie, P.2
Opatowsky, Y.3
Schlessinger, J.4
-
147
-
-
79960984152
-
Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy
-
Yao J, Wu X, Zhuang G, Kasman IM, Vogt T, Phan V, Shibuya M, Ferrara N, Bais C. Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy. Proc Natl Acad Sci USA 108: 11590-11595, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 11590-11595
-
-
Yao, J.1
Wu, X.2
Zhuang, G.3
Kasman, I.M.4
Vogt, T.5
Phan, V.6
Shibuya, M.7
Ferrara, N.8
Bais, C.9
-
148
-
-
84891093236
-
Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson's disease
-
YueX, Hariri DJ, Caballero B, Zhang S, Bartlett MJ, Kaut O, MountDW, Wullner U, Sherman SJ, Falk T. Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson's disease. Neuroscience 258: 385-400, 2014.
-
(2014)
Neuroscience
, vol.258
, pp. 385-400
-
-
Yue, X.1
Hariri, D.J.2
Caballero, B.3
Zhang, S.4
Bartlett, M.J.5
Kaut, O.6
Mount, D.W.7
Wullner, U.8
Sherman, S.J.9
Falk, T.10
-
149
-
-
81855169496
-
How neuropilin-1 regulates receptor tyrosine kinase signalling: The knowns and known unknowns
-
Zachary IC. How neuropilin-1 regulates receptor tyrosine kinase signalling: the knowns and known unknowns. Biochem Soc Trans 39: 1583-1591, 2011.
-
(2011)
Biochem Soc Trans
, vol.39
, pp. 1583-1591
-
-
Zachary, I.C.1
-
150
-
-
77952294182
-
Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction
-
Zentilin L, Puligadda U, Lionetti V, Zacchigna S, Collesi C, Pattarini L, Ruozi G, Camporesi S, Sinagra G, Pepe M, Recchia FA, Giacca M. Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction. FASEB J 24: 1467-1478, 2010.
-
(2010)
FASEB J
, vol.24
, pp. 1467-1478
-
-
Zentilin, L.1
Puligadda, U.2
Lionetti, V.3
Zacchigna, S.4
Collesi, C.5
Pattarini, L.6
Ruozi, G.7
Camporesi, S.8
Sinagra, G.9
Pepe, M.10
Recchia, F.A.11
Giacca, M.12
-
151
-
-
65549139264
-
VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis
-
Zhang F, Tang Z, Hou X, Lennartsson J, Li Y, Koch AW, Scotney P, Lee C, Arjunan P, Dong L, Kumar A, Rissanen TT, Wang B, Nagai N, Fons P, Fariss R, Zhang Y, Wawrousek E, Tansey G, Raber J, Fong GH, Ding H, Greenberg DA, Becker KG, Herbert JM, Nash A, Yla-Herttuala S, Cao Y, Watts RJ, Li X. VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis. Proc Natl Acad Sci USA 106: 6152-6157, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6152-6157
-
-
Zhang, F.1
Tang, Z.2
Hou, X.3
Lennartsson, J.4
Li, Y.5
Koch, A.W.6
Scotney, P.7
Lee, C.8
Arjunan, P.9
Dong, L.10
Kumar, A.11
Rissanen, T.T.12
Wang, B.13
Nagai, N.14
Fons, P.15
Fariss, R.16
Zhang, Y.17
Wawrousek, E.18
Tansey, G.19
Raber, J.20
Fong, G.H.21
Ding, H.22
Greenberg, D.A.23
Becker, K.G.24
Herbert, J.M.25
Nash, A.26
Yla-Herttuala, S.27
Cao, Y.28
Watts, R.J.29
Li, X.30
more..
-
152
-
-
84883774279
-
Differential expression of vascular endothelial growth factor isoforms and receptor subtypes in the infarcted heart
-
Zhao T, Zhao W, Chen Y, Liu L, Ahokas RA, Sun Y. Differential expression of vascular endothelial growth factor isoforms and receptor subtypes in the infarcted heart. Int J Cardiol 167: 2638-2645, 2012.
-
(2012)
Int J Cardiol
, vol.167
, pp. 2638-2645
-
-
Zhao, T.1
Zhao, W.2
Chen, Y.3
Liu, L.4
Ahokas, R.A.5
Sun, Y.6
-
153
-
-
79952169032
-
Vascular endothelial growth factor-B gene transfer exacerbates retinal and choroidal neovascularization and vasopermeability without promoting inflammation
-
Zhong X, Huang H, Shen J, Zacchigna S, Zentilin L, Giacca M, Vinores SA. Vascular endothelial growth factor-B gene transfer exacerbates retinal and choroidal neovascularization and vasopermeability without promoting inflammation. Mol Vis 17: 492-507, 2011.
-
(2011)
Mol Vis
, vol.17
, pp. 492-507
-
-
Zhong, X.1
Huang, H.2
Shen, J.3
Zacchigna, S.4
Zentilin, L.5
Giacca, M.6
Vinores, S.A.7
-
154
-
-
20244370028
-
Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic
-
Ziche M, Maglione D, Ribatti D, Morbidelli L, Lago CT, Battisti M, Paoletti I, Barra A, Tucci M, Parise G, Vincenti V, Granger HJ, Viglietto G, Persico MG. Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic. Lab Invest 76: 517-531, 1997.
-
(1997)
Lab Invest
, vol.76
, pp. 517-531
-
-
Ziche, M.1
Maglione, D.2
Ribatti, D.3
Morbidelli, L.4
Lago, C.T.5
Battisti, M.6
Paoletti, I.7
Barra, A.8
Tucci, M.9
Parise, G.10
Vincenti, V.11
Granger, H.J.12
Viglietto, G.13
Persico, M.G.14
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