-
1
-
-
0036782278
-
VEGF and the quest for tumour angiogenesis factors
-
DOI 10.1038/nrc909
-
Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2002; 2: 795-803. (Pubitemid 37328914)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.10
, pp. 795-803
-
-
Ferrara, N.1
-
2
-
-
0000912662
-
Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transparent ear chamber
-
Ide AG, Baker NH, Warren SL. Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transparent ear chamber. Am J Roentgenol 1939; 42: 891-899.
-
(1939)
Am J Roentgenol
, vol.42
, pp. 891-899
-
-
Ide, A.G.1
Baker, N.H.2
Warren, S.L.3
-
3
-
-
0015008620
-
Isolation of a tumor factor responsible for angiogenesis
-
Folkman J, Merler E, Abernathy C, Williams G. Isolation of a tumor factor responsible for angiogenesis. J Exp Med 1971; 133: 275-288.
-
(1971)
J Exp Med
, vol.133
, pp. 275-288
-
-
Folkman, J.1
Merler, E.2
Abernathy, C.3
Williams, G.4
-
4
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983; 219: 983-985.
-
(1983)
Science
, vol.219
, pp. 983-985
-
-
Senger, D.R.1
Galli, S.J.2
Dvorak, A.M.3
Perruzzi, C.A.4
Harvey, V.S.5
Dvorak, H.F.6
-
5
-
-
0024384470
-
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
-
DOI 10.1016/0006-291X(89)92678-8
-
Ferrara N, Henzel WJ. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 1989; 161: 851-858. (Pubitemid 19162712)
-
(1989)
Biochemical and Biophysical Research Communications
, vol.161
, Issue.2
, pp. 851-858
-
-
Ferrara, N.1
Henzel, W.J.2
-
6
-
-
0037703184
-
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
-
DOI 10.1038/nm884
-
Autiero M, Waltenberger J, Communi D, Kranz A, Moons L, Lambrechts D et al. Role of PlGF in the intra-and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med 2003; 9: 936-943. (Pubitemid 36889938)
-
(2003)
Nature Medicine
, vol.9
, Issue.7
, pp. 936-943
-
-
Autiero, M.1
Waltenberger, J.2
Communi, D.3
Kranz, A.4
Moons, L.5
Lambrechts, D.6
Kroll, J.7
Plaisance, S.8
De Mol, M.9
Bono, F.10
Kliche, S.11
Fellbrich, G.12
Ballmer-Hofer, K.13
Maglione, D.14
Mayr-Beyrle, U.15
Dewerchin, M.16
Dombrowski, S.17
Stanimirovic, D.18
Van Hummelen, P.19
Dehio, C.20
Hicklin, D.J.21
Persico, G.22
Herbert, J.-M.23
Communi, D.24
Shibuya, M.25
Collen, D.26
Conway, E.M.27
Carmeliet, P.28
more..
-
7
-
-
0026702970
-
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
-
Terman BI, Dougher-Vermazen M, Carrion ME, Dimitrov D, Armellino DC, Gospodarowicz D et al. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 1992; 187: 1579-1586.
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 1579-1586
-
-
Terman, B.I.1
Dougher-Vermazen, M.2
Carrion, M.E.3
Dimitrov, D.4
Armellino, D.C.5
Gospodarowicz, D.6
-
8
-
-
0032191129
-
Receptors for collapsin/semaphorins
-
DOI 10.1016/S0959-4388(98)80085-8
-
Fujisawa H, Kitsukawa T. Receptors for collapsin/semaphorins. Curr Opin Neurobiol 1998; 8: 587-592. (Pubitemid 28488419)
-
(1998)
Current Opinion in Neurobiology
, vol.8
, Issue.5
, pp. 587-592
-
-
Fujisawa, H.1
Kitsukawa, T.2
-
9
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform- specific receptor for vascular endothelial growth factor
-
DOI 10.1016/S0092-8674(00)81402-6
-
Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 1998; 92: 735-745. (Pubitemid 28155313)
-
(1998)
Cell
, vol.92
, Issue.6
, pp. 735-745
-
-
Soker, S.1
Takashima, S.2
Miao, H.Q.3
Neufeld, G.4
Klagsbrun, M.5
-
10
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature 2011; 473: 298-307.
-
(2011)
Nature
, vol.473
, pp. 298-307
-
-
Carmeliet, P.1
Jain, R.K.2
-
11
-
-
80052933197
-
Basic and therapeutic aspects of angiogenesis
-
Potente M, Gerhardt H, Carmeliet P. Basic and therapeutic aspects of angiogenesis. Cell 2011; 146: 873-887.
-
(2011)
Cell
, vol.146
, pp. 873-887
-
-
Potente, M.1
Gerhardt, H.2
Carmeliet, P.3
-
12
-
-
34249689753
-
Molecular regulation of angiogenesis and lymphangiogenesis
-
DOI 10.1038/nrm2183, PII NRM2183
-
Adams RH, Alitalo K. Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol Cell Biol 2007; 8: 464-478. (Pubitemid 46823443)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.6
, pp. 464-478
-
-
Adams, R.H.1
Alitalo, K.2
-
14
-
-
79952269928
-
Non-redundant functions of the protein isoforms arising from alternative splicing of the VEGF-A pre-mRNA
-
Giacca M. Non-redundant functions of the protein isoforms arising from alternative splicing of the VEGF-A pre-mRNA. Transcription 2010; 1: 149-153.
-
(2010)
Transcription
, vol.1
, pp. 149-153
-
-
Giacca, M.1
-
15
-
-
34250772826
-
Current status of cardiovascular gene therapy
-
DOI 10.1038/sj.mt.6300175, PII 6300175
-
Rissanen TT, Yla-Herttuala S. Current status of cardiovascular gene therapy. Mol Ther 2007; 15: 1233-1247. (Pubitemid 46965318)
-
(2007)
Molecular Therapy
, vol.15
, Issue.7
, pp. 1233-1247
-
-
Rissanen, T.T.1
Yla-Herttuala, S.2
-
16
-
-
0037453099
-
The VIVA trial: Vascular endothelial growth factor in ischemia for vascular angiogenesis
-
DOI 10.1161/01.CIR.0000061911.47710.8A
-
Henry TD, Annex BH, McKendall GR, Azrin MA, Lopez JJ, Giordano FJ et al. The VIVA trial: vascular endothelial growth factor in ischemia for vascular angiogenesis. Circulation 2003; 107: 1359-1365. (Pubitemid 36350732)
-
(2003)
Circulation
, vol.107
, Issue.10
, pp. 1359-1365
-
-
Henry, T.D.1
Annex, B.H.2
McKendall, G.R.3
Azrin, M.A.4
Lopez, J.J.5
Giordano, F.J.6
Shah, P.K.7
Willerson, J.T.8
Benza, R.L.9
Berman, D.S.10
Gibson, C.M.11
Bajamonde, A.12
Rundle, A.C.13
Fine, J.14
McCluskey, E.R.15
-
17
-
-
0034531401
-
Efficacy of intracoronary versus intravenous FGF-2 in a pig model of chronic myocardial ischemia
-
DOI 10.1016/S0003-4975(00)02018-X, PII S000349750002018X
-
Sato K, Laham RJ, Pearlman JD, Novicki D, Sellke FW, Simons M et al. Efficacy of intracoronary versus intravenous FGF-2 in a pig model of chronic myocardial ischemia. Ann Thorac Surg 2000; 70: 2113-2118. (Pubitemid 32015318)
-
(2000)
Annals of Thoracic Surgery
, vol.70
, Issue.6
, pp. 2113-2118
-
-
Sato, K.1
Laham, R.J.2
Pearlman, J.D.3
Novicki, D.4
Sellke, F.W.5
Simons, M.6
Post, M.J.7
-
18
-
-
0032548023
-
Vascular endothelial growth factor: Gene therapy and therapeutic angiogenesis
-
Isner JM. Vascular endothelial growth factor: gene therapy and therapeutic angiogenesis. Am J Cardiol 1998; 82: 63S-64S.
-
(1998)
Am J Cardiol
, vol.82
-
-
Isner, J.M.1
-
19
-
-
15844420661
-
165 in patient with ischaemic limb
-
DOI 10.1016/S0140-6736(96)03361-2
-
Isner JM, Pieczek A, Schainfeld R, Blair R, Haley L, Asahara Tet al. Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb. Lancet 1996; 348: 370-374. (Pubitemid 26261511)
-
(1996)
Lancet
, vol.348
, Issue.9024
, pp. 370-374
-
-
Isner, J.M.1
Pieczek, A.2
Schainfeld, R.3
Blair, R.4
Haley, L.5
Asahara, T.6
Rosenfield, K.7
Razvi, S.8
Walsh, K.9
Symes, J.F.10
-
20
-
-
0032583951
-
165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia
-
Baumgartner I, Pieczek A, Manor O, Blair R, Kearney M, Walsh K et al. Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation 1998; 97: 1114-1123. (Pubitemid 28152883)
-
(1998)
Circulation
, vol.97
, Issue.12
, pp. 1114-1123
-
-
Baumgartner, I.1
Pieczek, A.2
Manor, O.3
Blair, R.4
Kearney, M.5
Walsh, K.6
Isner, J.M.7
-
21
-
-
4644292454
-
Vascular endothelial growth factor-induced angiogenic gene therapy in patients with peripheral artery disease
-
Kim HJ, Jang SY, Park JI, Byun J, Kim DI, Do YS et al. Vascular endothelial growth factor-induced angiogenic gene therapy in patients with peripheral artery disease. Exp Mol Med 2004; 36: 336-344. (Pubitemid 39279529)
-
(2004)
Experimental and Molecular Medicine
, vol.36
, Issue.4
, pp. 336-344
-
-
Kim, H.-J.1
Jang, S.Y.2
Park, J.-I.3
Byun, J.4
Kim, D.-I.5
Do, Y.-S.6
Kim, J.-M.7
Kim, S.8
Kim, B.-M.9
Kim, W.-B.10
Kim, D.-K.11
-
22
-
-
0034612203
-
Lower-extremity edema associated with gene transfer of naked DNA encoding vascular endothelial growth factor
-
Baumgartner I, Rauh G, Pieczek A, Wuensch D, Magner M, Kearney M et al. Lowerextremity edema associated with gene transfer of naked DNA encoding vascular endothelial growth factor. Ann Intern Med 2000; 132: 880-884. (Pubitemid 30346850)
-
(2000)
Annals of Internal Medicine
, vol.132
, Issue.11
, pp. 880-884
-
-
Baumgartner, I.1
Rauh, G.2
Pieczek, A.3
Wuensch, D.4
Magner, M.5
Kearney, M.6
Schainfeld, R.7
Isner, J.M.8
-
23
-
-
0032578961
-
165 as sole therapy for myocardial ischemia
-
Losordo DW, Vale PR, Symes JF, Dunnington CH, Esakof DD, Maysky M et al. Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. Circulation 1998; 98: 2800-2804. (Pubitemid 29003959)
-
(1998)
Circulation
, vol.98
, Issue.25
, pp. 2800-2804
-
-
Losordo, D.W.1
Vale, P.R.2
Symes, J.F.3
Dunnington, C.H.4
Esakof, D.D.5
Maysky, M.6
Ashare, A.B.7
Lathi, K.8
Isner, J.M.9
-
24
-
-
0032698604
-
Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease
-
discussion, 836-837
-
Symes JF, Losordo DW, Vale PR, Lathi KG, Esakof DD, Mayskiy M et al. Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease. Ann Thorac Surg 1999; 68: 830-836; discussion 836-837.
-
(1999)
Ann Thorac Surg
, vol.68
, pp. 830-836
-
-
Symes, J.F.1
Losordo, D.W.2
Vale, P.R.3
Lathi, K.G.4
Esakof, D.D.5
Mayskiy, M.6
-
25
-
-
0042564700
-
One-year follow-up of direct myocardial gene transfer of vascular endothelial growth factor-2 using naked plasmid deoxyribonucleic acid by way of thoracotomy in no-option patients
-
DOI 10.1016/S0002-9149(03)00661-1
-
Fortuin FD, Vale P, Losordo DW, Symes J, DeLaria GA, Tyner JJ et al. One-year follow-up of direct myocardial gene transfer of vascular endothelial growth factor-2 using naked plasmid deoxyribonucleic acid by way of thoracotomy in no-option patients. Am J Cardiol 2003; 92: 436-439. (Pubitemid 36959880)
-
(2003)
American Journal of Cardiology
, vol.92
, Issue.4
, pp. 436-439
-
-
Fortuin, F.D.1
Vale, P.2
Losordo, D.W.3
Symes, J.4
Delaria, G.A.5
Tyner, J.J.6
Schaer, G.L.7
March, R.8
Snell, R.J.9
Henry, T.D.10
Van Camp, J.11
Lopez, J.J.12
Richenbacher, W.13
Isner, J.M.14
Schatz, R.A.15
-
26
-
-
20144389391
-
Long-term (2-year) clinical events following transthoracic intramyocardial gene transfer of VEGF-2 in no-option patients
-
DOI 10.1111/j.1540-8183.2005.04026.x
-
Reilly JP, Grise MA, Fortuin FD, Vale PR, Schaer GL, Lopez J et al. Long-term (2-year) clinical events following transthoracic intramyocardial gene transfer of VEGF-2 in nooption patients. J Interv Cardiol 2005; 18: 27-31. (Pubitemid 40468771)
-
(2005)
Journal of Interventional Cardiology
, vol.18
, Issue.1
, pp. 27-31
-
-
Reilly, J.P.1
Grise, M.A.2
Fortuin, F.D.3
Vale, P.R.4
Schaer, G.L.5
Lopez, J.6
Van Camp, J.R.7
Henry, T.8
Richenbacher, W.E.9
Losordo, D.W.10
Schatz, R.A.11
Isner, J.M.12
-
27
-
-
0034730094
-
Left ventricular electromechanical mapping to assess efficacy of phvegf (165) gene transfer for therapeutic angiogenesis in chronic myocardial ischemia
-
Vale PR, Losordo DW, Milliken CE, Maysky M, Esakof DD, Symes JF et al. Left ventricular electromechanical mapping to assess efficacy of phVEGF (165) gene transfer for therapeutic angiogenesis in chronic myocardial ischemia. Circulation 2000; 102: 965-974.
-
(2000)
Circulation
, vol.102
, pp. 965-974
-
-
Vale, P.R.1
Losordo, D.W.2
Milliken, C.E.3
Maysky, M.4
Esakof, D.D.5
Symes, J.F.6
-
28
-
-
0034767908
-
165 as sole therapy in patients with refractory coronary artery disease - 12-Month follow-up: Angiogenic gene therapy
-
DOI 10.1046/j.1365-2796.2001.00905.x
-
Sarkar N, Ruck A, Kallner G, Y-Hassan S, Blomberg P, Islam KB et al. Effects of intramyocardial injection of phVEGF-A165 as sole therapy in patients with refractory coronary artery disease-12-month follow-up: angiogenic gene therapy. J Intern Med 2001; 250: 373-381. (Pubitemid 32990045)
-
(2001)
Journal of Internal Medicine
, vol.250
, Issue.5
, pp. 373-381
-
-
Sarkar, N.1
Ruck, A.2
Kallner, G.3
Y-Hassan, S.4
Blomberg, P.5
Islam, K.B.6
Van Der Linden, J.7
Lindblom, D.8
Nygren, A.T.9
Lind, B.10
Brodin, L.-A.11
Drvota, V.12
Sylven, C.13
-
29
-
-
0037197740
-
Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia
-
DOI 10.1161/01.CIR.0000015982.70785.B7
-
Losordo DW, Vale PR, Hendel RC, Milliken CE, Fortuin FD, Cummings N et al. Phase 1/placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia. Circulation 2002; 105: 2012-2018. (Pubitemid 34465261)
-
(2002)
Circulation
, vol.105
, Issue.17
, pp. 2012-2018
-
-
Losordo, D.W.1
Vale, P.R.2
Hendel, R.C.3
Milliken, C.E.4
Fortuin, F.D.5
Cummings, N.6
Schatz, R.A.7
Asahara, T.8
Isner, J.M.9
Kuntz, R.E.10
-
30
-
-
84862018238
-
Abstract 15235: High-dose plasmid VEGF gene transfer in patients with severe coronary artery disease: Final results of the first Latin American trial of gene therapy in myocardial ischemia
-
Mendiz O, Favaloro L, Diez M, Valdivieso L, Bercovich A, Criscuolo M et al. Abstract 15235: high-dose plasmid VEGF gene transfer in patients with severe coronary artery disease: final results of the first Latin American trial of gene therapy in myocardial ischemia. Circulation 2011; 124 (Suppl.): A15235.
-
(2011)
Circulation
, vol.124
, Issue.SUPPL.
-
-
Mendiz, O.1
Favaloro, L.2
Diez, M.3
Valdivieso, L.4
Bercovich, A.5
Criscuolo, M.6
-
31
-
-
24644445081
-
NOGA-guided analysis of regional myocardial perfusion abnormalities treated with intramyocardial injections of plasmid encoding vascular endothelial growth factor A-165 in patients with chronic myocardial ischemia: Subanalysis of the EUROINJECT-ONE multicenter double-blind randomized study
-
DOI 10.1161/01.CIRCULATIONAHA.105.525782
-
Gyongyosi M, Khorsand A, Zamini S, Sperker W, Strehblow C, Kastrup J et al. NOGAguided analysis of regional myocardial perfusion abnormalities treated with intramyocardial injections of plasmid encoding vascular endothelial growth factor A-165 in patients with chronic myocardial ischemia: subanalysis of the EUROINJECT-ONE multicenter double-blind randomized study. Circulation 2005; 112 (Suppl): I157-I165. (Pubitemid 41266668)
-
(2005)
Circulation
, vol.112
, Issue.9 SUPPL.
-
-
Gyongyosi, M.1
Khorsand, A.2
Zamini, S.3
Sperker, W.4
Strehblow, C.5
Kastrup, J.6
Jorgensen, E.7
Hesse, B.8
Tagil, K.9
Botker, H.E.10
Ruzyllo, W.11
Teresinska, A.12
Dudek, D.13
Hubalewska, A.14
Ruck, A.15
Nielsen, S.S.16
Graf, S.17
Mundigler, G.18
Novak, J.19
Sochor, H.20
Maurer, G.21
Glogar, D.22
Sylven, C.23
more..
-
32
-
-
20144386684
-
165 gene therapy in patients with stable severe angina pectoris: A randomized double-blind placebo-controlled study: The Euroinject One trial
-
DOI 10.1016/j.jacc.2004.12.068
-
Kastrup J, Jorgensen E, Ruck A, Tagil K, Glogar D, Ruzyllo W et al. Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris. A randomized double-blind placebo-controlled study: the Euroinject One Trial. J Am Coll Cardiol 2005; 45: 982-988. (Pubitemid 40432426)
-
(2005)
Journal of the American College of Cardiology
, vol.45
, Issue.7
, pp. 982-988
-
-
Kastrup, J.1
Jorgensen, E.2
Ruck, A.3
Tagil, K.4
Glogar, D.5
Ruzyllo, W.6
Botker, H.E.7
Dudek, D.8
Drvota, V.9
Hesse, B.10
Thuesen, L.11
Blomberg, P.12
Gyongyosi, M.13
Sylven, C.14
-
33
-
-
67349287066
-
VEGF gene therapy fails to improve perfusion of ischemic myocardium in patients with advanced coronary disease: Results of the NORTHERN trial
-
Stewart DJ, Kutryk MJ, Fitchett D, Freeman M, Camack N, Su Y et al. VEGF gene therapy fails to improve perfusion of ischemic myocardium in patients with advanced coronary disease: results of the NORTHERN trial. Mol Ther 2009; 17: 1109-1115.
-
(2009)
Mol Ther
, vol.17
, pp. 1109-1115
-
-
Stewart, D.J.1
Kutryk, M.J.2
Fitchett, D.3
Freeman, M.4
Camack, N.5
Su, Y.6
-
34
-
-
33748044611
-
165 plasmid followed by granulocyte-colony stimulating factor to induce angiogenesis in patients with severe chronic ischaemic heart disease
-
DOI 10.1093/eurheartj/ehl117
-
Ripa RS, Wang Y, Jorgensen E, Johnsen HE, Hesse B, Kastrup J. Intramyocardial injection of vascular endothelial growth factor-A165 plasmid followed by granulocytecolony stimulating factor to induce angiogenesis in patients with severe chronic ischaemic heart disease. Eur Heart J 2006; 27: 1785-1792. (Pubitemid 44297382)
-
(2006)
European Heart Journal
, vol.27
, Issue.15
, pp. 1785-1792
-
-
Ripa, R.S.1
Wang, Y.2
Jorgensen, E.3
Johnsen, H.E.4
Hesse, B.5
Kastrup, J.6
-
35
-
-
79952447660
-
Intramyocardial plasmid-encoding human vascular endothelial growth factor A165/basic fibroblast growth factor therapy using percutaneous transcatheter approach in patients with refractory coronary artery disease (VIF-CAD)
-
Kukula K, Chojnowska L, Dabrowski M, Witkowski A, Chmielak Z, Skwarek M et al. Intramyocardial plasmid-encoding human vascular endothelial growth factor A165/basic fibroblast growth factor therapy using percutaneous transcatheter approach in patients with refractory coronary artery disease (VIF-CAD). Am Heart J 2011; 161: 581-589.
-
(2011)
Am Heart J
, vol.161
, pp. 581-589
-
-
Kukula, K.1
Chojnowska, L.2
Dabrowski, M.3
Witkowski, A.4
Chmielak, Z.5
Skwarek, M.6
-
36
-
-
33745643590
-
Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: A double-blind randomized trial
-
DOI 10.1089/hum.2006.17.683
-
Kusumanto YH, van Weel V, Mulder NH, Smit AJ, van den Dungen JJ, Hooymans JM et al. Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: a doubleblind randomized trial. Hum Gene Ther 2006; 17: 683-691. (Pubitemid 43970708)
-
(2006)
Human Gene Therapy
, vol.17
, Issue.6
, pp. 683-691
-
-
Kusumanto, Y.H.1
Van Weel, V.2
Mulder, N.H.3
Smit, A.J.4
Van Den Dungen, J.J.A.M.5
Hooymans, J.M.M.6
Sluiter, W.J.7
Tio, R.A.8
Quax, P.H.A.9
Gans, R.O.B.10
Dullaart, R.P.F.11
Hospers, G.A.P.12
-
37
-
-
0035815697
-
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions: Activation of vascular endothelial growth factor A
-
DOI 10.1074/jbc.M011172200
-
Liu PQ, Rebar EJ, Zhang L, Liu Q, Jamieson AC, Liang Y et al. Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A. J Biol Chem 2001; 276: 11323-11334. (Pubitemid 38089322)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.14
, pp. 11323-11334
-
-
Liu, P.-Q.1
Rebar, E.J.2
Zhang, L.3
Liu, Q.4
Jamieson, A.C.5
Liang, Y.6
Qi, H.7
Li, P.-X.8
Chen, B.9
Mendel, M.C.10
Zhong, X.11
Lee, Y.-L.12
Eisenberg, S.P.13
Spratt, S.K.14
Case, C.C.15
Wolffe, A.P.16
-
38
-
-
0036912846
-
Induction of angiogenesis in a mouse model using engineered transcription factors
-
DOI 10.1038/nm795
-
Rebar EJ, Huang Y, Hickey R, Nath AK, Meoli D, Nath S et al. Induction of angiogenesis in a mouse model using engineered transcription factors. Nat Med 2002; 8: 1427-1432. (Pubitemid 36019428)
-
(2002)
Nature Medicine
, vol.8
, Issue.12
, pp. 1427-1432
-
-
Rebar, E.J.1
Huang, Y.2
Hickey, R.3
Nath, A.K.4
Meoli, D.5
Nath, S.6
Chen, B.7
Xu, L.8
Liang, Y.9
Jamieson, A.C.10
Zhang, L.11
Spratt, S.K.12
Case, C.C.13
Wolffe, A.14
Giordano, F.J.15
-
39
-
-
6444236227
-
Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia
-
DOI 10.1161/01.CIR.0000145139.53840.49
-
Dai Q, Huang J, Klitzman B, Dong C, Goldschmidt-Clermont PJ, March KL et al. Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. Circulation 2004; 110: 2467-2475. (Pubitemid 39407355)
-
(2004)
Circulation
, vol.110
, Issue.16
, pp. 2467-2475
-
-
Dai, Q.1
Huang, J.2
Klitzman, B.3
Dong, C.4
Goldschmidt-Clermont, P.J.5
March, K.L.6
Rokovich, J.7
Johnstone, B.8
Rebar, E.J.9
Spratt, S.K.10
Case, C.C.11
Kontos, C.D.12
Annex, B.H.13
-
40
-
-
33645838355
-
An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice
-
DOI 10.1096/fj.04-3670fje
-
Yu J, Lei L, Liang Y, Hinh L, Hickey RP, Huang Y et al. An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice. FASEB J 2006; 20: 479-481. (Pubitemid 46671222)
-
(2006)
FASEB Journal
, vol.20
, Issue.3
, pp. 479-481
-
-
Yu, J.1
Lei, L.2
Liang, Y.3
Hinh, L.4
Hickey, R.P.5
Huang, Y.6
Liu, D.7
Yeh, J.L.8
Rebar, E.9
Case, C.10
Spratt, K.11
Sessa, W.C.12
Giordano, F.J.13
-
41
-
-
68949163249
-
Inducible adenoassociated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression
-
Tafuro S, Ayuso E, Zacchigna S, Zentilin L, Moimas S, Dore F et al. Inducible adenoassociated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression. Cardiovasc Res 2009; 83: 663-671.
-
(2009)
Cardiovasc Res
, vol.83
, pp. 663-671
-
-
Tafuro, S.1
Ayuso, E.2
Zacchigna, S.3
Zentilin, L.4
Moimas, S.5
Dore, F.6
-
42
-
-
79958118819
-
Effect of fibroblast growth factor NV1FGF on amputation and death: A randomised placebo-controlled trial of gene therapy in critical limb ischaemia
-
Belch J, Hiatt WR, Baumgartner I, Driver IV, Nikol S, Norgren L et al. Effect of fibroblast growth factor NV1FGF on amputation and death: a randomised placebo-controlled trial of gene therapy in critical limb ischaemia. Lancet 2011; 377: 1929-1937.
-
(2011)
Lancet
, vol.377
, pp. 1929-1937
-
-
Belch, J.1
Hiatt, W.R.2
Baumgartner, I.3
Driver, I.V.4
Nikol, S.5
Norgren, L.6
-
43
-
-
0035859782
-
121 improves lower-extremity endothelial function and flow reserve
-
Rajagopalan S, Shah M, Luciano A, Crystal R, Nabel EG. Adenovirus-mediated gene transfer of VEGF (121) improves lower-extremity endothelial function and flow reserve. Circulation 2001; 104: 753-755. (Pubitemid 32762670)
-
(2001)
Circulation
, vol.104
, Issue.7
, pp. 753-755
-
-
Rajagopalan, S.1
Shah, M.2
Luciano, A.3
Crystal, R.4
Nabel, E.G.5
-
44
-
-
0036710990
-
Phase i study of direct administration of a replication deficient adenovirus vector containing the vascular endothelial growth factor cDNA (CI-1023) to patients with claudication
-
DOI 10.1016/S0002-9149(02)02524-9, PII S0002914902025249
-
Rajagopalan S, Trachtenberg J, Mohler E, Olin J, McBride S, Pak R et al. Phase I study of direct administration of a replication deficient adenovirus vector containing the vascular endothelial growth factor cDNA (CI-1023) to patients with claudication. Am J Cardiol 2002; 90: 512-516. (Pubitemid 35251823)
-
(2002)
American Journal of Cardiology
, vol.90
, Issue.5
, pp. 512-516
-
-
Rajagopalan, S.1
Trachtenberg, J.2
Mohler, E.3
Olin, J.4
McBride, S.5
Pak, R.6
Rasmussen, H.7
Crystal, R.8
-
45
-
-
0038281504
-
Regional angiogenesis with vascular endothelial growth factor (VEGF) in peripheral arterial disease: Design of the RAVE trial
-
DOI 10.1016/S0002-8703(03)00102-9
-
Rajagopalan S, Mohler III E, Lederman RJ, Saucedo J, Mendelsohn FO, Olin J et al. Regional angiogenesis with vascular endothelial growth factor (VEGF) in peripheral arterial disease: design of the RAVE trial. Am Heart J 2003; 145: 1114-1118. (Pubitemid 36688266)
-
(2003)
American Heart Journal
, vol.145
, Issue.6
, pp. 1114-1118
-
-
Rajagopalan, S.1
Mohler Iii, E.2
Lederman, R.J.3
Saucedo, J.4
Mendelsohn, F.O.5
Olin, J.6
Blebea, J.7
Goldman, C.8
Trachtenberg, J.D.9
Pressler, M.10
Rasmussen, H.11
Annex, B.H.12
Hirsch, A.T.13
-
46
-
-
0142023866
-
Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: A phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication
-
DOI 10.1161/01.CIR.0000093398.16124.29
-
Rajagopalan S, Mohler III ER, Lederman RJ, Mendelsohn FO, Saucedo JF, Goldman CK et al. Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication. Circulation 2003; 108: 1933-1938. (Pubitemid 37296537)
-
(2003)
Circulation
, vol.108
, Issue.16
, pp. 1933-1938
-
-
Rajagopalan, S.1
Mohler Iii, E.R.2
Lederman, R.J.3
Mendelsohn, F.O.4
Saucedo, J.F.5
Goldman, C.K.6
Blebea, J.7
MacKo, J.8
Kessler, P.D.9
Rasmussen, H.S.10
Annex, B.H.11
-
47
-
-
0033520056
-
Angiogenesis gene therapy: Phase i assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease
-
Rosengart TK, Lee LY, Patel SR, Sanborn TA, Parikh M, Bergman GW et al. Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation 1999; 100: 468-474. (Pubitemid 29360154)
-
(1999)
Circulation
, vol.100
, Issue.5
, pp. 468-474
-
-
Rosengart, T.K.1
Lee, L.Y.2
Patel, S.R.3
Sanborn, T.A.4
Parikh, M.5
Bergman, G.W.6
Hachamovitch, R.7
Szulc, M.8
Kligfield, P.D.9
Okin, P.M.10
Hahn, R.T.11
Devereux, R.B.12
Post, M.R.13
Hackett, N.R.14
Foster, T.15
Grasso, T.M.16
Lesser, M.L.17
Isom, O.W.18
Crystal, R.G.19
-
48
-
-
33748155036
-
121 (AdVEGF121) versus maximum medical treatment
-
DOI 10.1038/sj.gt.3302802, PII 3302802
-
Stewart DJ, Hilton JD, Arnold JM, Gregoire J, Rivard A, Archer SL et al. Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF (121) (AdVEGF121) versus maximum medical treatment. Gene Therapy 2006; 13: 1503-1511. (Pubitemid 44574158)
-
(2006)
Gene Therapy
, vol.13
, Issue.21
, pp. 1503-1511
-
-
Stewart, D.J.1
Hilton, J.D.2
Arnold, J.M.O.3
Gregoire, J.4
Rivard, A.5
Archer, S.L.6
Charbonneau, F.7
Cohen, E.8
Curtis, M.9
Buller, C.E.10
Mendelsohn, F.O.11
Dib, N.12
Page, P.13
Ducas, J.14
Plante, S.15
Sullivan, J.16
MacKo, J.17
Rasmussen, C.18
Kessler, P.D.19
Rasmussen, H.S.20
more..
-
49
-
-
33748333148
-
A randomized, double-blind, placebo-controlled, multicenter, pilot study of the safety and feasibility of catheter-based intramyocardial injection of AdVEGF121 in patients with refractory advanced coronary artery disease
-
DOI 10.1002/ccd.20859
-
Fuchs S, Dib N, Cohen BM, Okubagzi P, Diethrich EB, Campbell A et al. A randomized, double-blind, placebo-controlled, multicenter, pilot study of the safety and feasibility of catheter-based intramyocardial injection of AdVEGF121 in patients with refractory advanced coronary artery disease. Catheter Cardiovasc Interv 2006; 68: 372-378. (Pubitemid 44330674)
-
(2006)
Catheterization and Cardiovascular Interventions
, vol.68
, Issue.3
, pp. 372-378
-
-
Fuchs, S.1
Dib, N.2
Cohen, B.M.3
Okubagzi, P.4
Diethrich, E.B.5
Campbell, A.6
MacKo, J.7
Kessler, P.D.8
Rasmussen, H.S.9
Epstein, S.E.10
Kornowski, R.11
-
50
-
-
79954490234
-
A randomised, double-blind, placebo-controlled, multicentre study of the safety and efficacy of BIOBYPASS (AdGVVEGF121.10NH) gene therapy in patients with refractory advanced coronary artery disease: The NOVA trial
-
Kastrup J, Jorgensen E, Fuchs S, Nikol S, Botker HE, Gyongyosi M et al. A randomised, double-blind, placebo-controlled, multicentre study of the safety and efficacy of BIOBYPASS (AdGVVEGF121.10NH) gene therapy in patients with refractory advanced coronary artery disease: the NOVA trial. EuroIntervention 2011; 6: 813-818.
-
(2011)
Euro Intervention
, vol.6
, pp. 813-818
-
-
Kastrup, J.1
Jorgensen, E.2
Fuchs, S.3
Nikol, S.4
Botker, H.E.5
Gyongyosi, M.6
-
51
-
-
0036665610
-
Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: A randomized, placebo-controlled, double-blinded phase II study
-
DOI 10.1006/mthe.2002.0638
-
Makinen K, Manninen H, Hedman M, Matsi P, Mussalo H, Alhava E et al. Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebo-controlled, double-blinded phase II study. Mol Ther 2002; 6: 127-133. (Pubitemid 36124280)
-
(2002)
Molecular Therapy
, vol.6
, Issue.1
, pp. 127-133
-
-
Makinen, K.1
Mannine, H.2
Hedman, M.3
Matsi, P.4
Mussalo, H.5
Alhava, E.6
Yla-Herttuala, S.7
-
52
-
-
0038210219
-
Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: Phase II results of the Kuopio angiogenesis trial (KAT)
-
Hedman M, Hartikainen J, Syvanne M, Stjernvall J, Hedman A, Kivela A et al. Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: phase II results of the Kuopio Angiogenesis Trial (KAT). Circulation 2003; 107: 2677-2683. (Pubitemid 36667240)
-
(2003)
Circulation
, vol.107
, Issue.21
, pp. 2677-2683
-
-
Hedman, M.1
Hartikainen, J.2
Syvanne, M.3
Stjernvall, J.4
Hedman, A.5
Kivela, A.6
Vanninen, E.7
Mussalo, H.8
Kauppila, E.9
Simula, S.10
Narvanen, O.11
Rantala, A.12
Peuhkurinen, K.13
Nieminen, M.S.14
Laakso, M.15
Yla-Herttuala, S.16
-
53
-
-
67349112757
-
Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer
-
Hedman M, Muona K, Hedman A, Kivela A, Syvanne M, Eranen J et al. Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer. Gene Therapy 2009; 16: 629-634.
-
(2009)
Gene Therapy
, vol.16
, pp. 629-634
-
-
Hedman, M.1
Muona, K.2
Hedman, A.3
Kivela, A.4
Syvanne, M.5
Eranen, J.6
-
54
-
-
84859591761
-
10-year safety followup in patients with local VEGF gene transfer to ischemic lower limb
-
e-pub ahead of print 21 July 2011,doi:10.1038/gt.2011.109
-
Muona K, Makinen K, Hedman M, Manninen H, Yla-Herttuala S. 10-year safety followup in patients with local VEGF gene transfer to ischemic lower limb. Gene Therapy 2011; e-pub ahead of print 21 July 2011; doi:10.1038/gt.2011.109.
-
(2011)
Gene Therapy
-
-
Muona, K.1
Makinen, K.2
Hedman, M.3
Manninen, H.4
Yla-Herttuala, S.5
-
55
-
-
10744232374
-
Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart
-
DOI 10.1161/01.CIR.0000115519.03688.A2
-
Rutanen J, Rissanen TT, Markkanen JE, Gruchala M, Silvennoinen P, Kivela A et al. Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart. Circulation 2004; 109: 1029-1035. (Pubitemid 38282857)
-
(2004)
Circulation
, vol.109
, Issue.8
, pp. 1029-1035
-
-
Rutanen, J.1
Rissanen, T.T.2
Markkanen, J.E.3
Gruchala, M.4
Silvennoinen, P.5
Kivela, A.6
Hedman, A.7
Hedman, M.8
Heikura, T.9
Orden, M.-R.10
Stacker, S.A.11
Achen, M.G.12
Hartikainen, J.13
Yla-Herttuala, S.14
-
56
-
-
0035512016
-
Clinical protocol A phase IIb, randomized, multicenter, double-blind study of the efficacy and safety of Trinam (EG004) in stenosis prevention at the graft-vein anastomosis site in dialysis patients
-
Fuster V, Charlton P, Boyd A. Clinical protocol. A phase IIb, randomized, multicenter, double-blind study of the efficacy and safety of Trinam (EG004) in stenosis prevention at the graft-vein anastomosis site in dialysis patients. Hum Gene Ther 2001; 12: 2025-2027.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 2025-2027
-
-
Fuster, V.1
Charlton, P.2
Boyd, A.3
-
57
-
-
0028832360
-
Transient expression of genes transferred in vivo into heart using first-generation adenoviral vectors: Role of the immune response
-
Gilgenkrantz H, Duboc D, Juillard V, Couton D, Pavirani A, Guillet JG et al. Transient expression of genes transferred in vivo into heart using first-generation adenoviral vectors: role of the immune response. Hum Gene Ther 1995; 6: 1265-1274.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1265-1274
-
-
Gilgenkrantz, H.1
Duboc, D.2
Juillard, V.3
Couton, D.4
Pavirani, A.5
Guillet, J.G.6
-
58
-
-
54249126862
-
Gene therapy using adeno-associated virus vectors
-
Daya S, Berns KI. Gene therapy using adeno-associated virus vectors. Clin Microbiol Rev 2008; 21: 583-593.
-
(2008)
Clin Microbiol Rev
, vol.21
, pp. 583-593
-
-
Daya, S.1
Berns, K.I.2
-
59
-
-
79954622209
-
Therapeutic in vivo gene transfer for genetic disease using AAV: Progress and challenges
-
Mingozzi F, High KA. Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges. Nat Rev Genet 2011; 12: 341-355.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 341-355
-
-
Mingozzi, F.1
High, K.A.2
-
60
-
-
0037689525
-
Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors
-
DOI 10.1016/S1525-0016(03)00034-0
-
Arsic N, Zentilin L, Zacchigna S, Santoro D, Stanta G, Salvi S et al. Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors. Mol Ther 2003; 7: 450-459. (Pubitemid 36553413)
-
(2003)
Molecular Therapy
, vol.7
, Issue.4
, pp. 450-459
-
-
Arsic, N.1
Zentilin, L.2
Zacchigna, S.3
Santoro, D.4
Stanta, G.5
Salvi, A.6
Sinagra, G.7
Giacca, M.8
-
61
-
-
40549138765
-
Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins
-
DOI 10.1242/jcs.003632
-
Cervelli T, Palacios JA, Zentilin L, Mano M, Schwartz RA, Weitzman MD et al. Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins. J Cell Sci 2008; 121 (Part 3): 349-357. (Pubitemid 351356706)
-
(2008)
Journal of Cell Science
, vol.121
, Issue.3
, pp. 349-357
-
-
Cervelli, T.1
Palacios, J.A.2
Zentilin, L.3
Mano, M.4
Schwartz, R.A.5
Weitzman, M.D.6
Giacca, M.7
-
62
-
-
0037182861
-
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
-
DOI 10.1038/nature00821
-
Gerber HP, Malik AK, Solar GP, Sherman D, Liang XH, Meng G et al. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Nature 2002; 417: 954-958. (Pubitemid 34716872)
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 954-958
-
-
Gerber, H.-P.1
Malik, A.K.2
Solar, G.P.3
Sherman, D.4
Liang, X.H.5
Meng, G.6
Hong, K.7
Marsters, J.C.8
Ferrara, N.9
-
63
-
-
0036344495
-
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
-
Luttun A, Tjwa M, Moons L, Wu Y, Angelillo-Scherrer A, Liao F et al. Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat Med 2002; 8: 831-840.
-
(2002)
Nat Med
, vol.8
, pp. 831-840
-
-
Luttun, A.1
Tjwa, M.2
Moons, L.3
Wu, Y.4
Angelillo-Scherrer, A.5
Liao, F.6
-
64
-
-
0043156082
-
Placenta growth factor activates monocytes and correlates with sickle cell disease severity
-
DOI 10.1182/blood-2002-11-3422
-
Perelman N, Selvaraj SK, Batra S, Luck LR, Erdreich-Epstein A, Coates TD et al. Placenta growth factor activates monocytes and correlates with sickle cell disease severity. Blood 2003; 102: 1506-1514. (Pubitemid 36988063)
-
(2003)
Blood
, vol.102
, Issue.4
, pp. 1506-1514
-
-
Perelman, N.1
Selvaraj, S.K.2
Batra, S.3
Luck, L.R.4
Erdreich-Epstein, A.5
Coates, T.D.6
Kalra, V.K.7
Malik, P.8
-
65
-
-
25844458274
-
Hepatocyte growth factor as well as vascular endothelial growth factor gene induction effectively promotes liver regeneration after hepatectomy in Solt-Farber rats
-
Oe H, Kaido T, Mori A, Onodera H, Imamura M. Hepatocyte growth factor as well as vascular endothelial growth factor gene induction effectively promotes liver regeneration after hepatectomy in Solt-Farber rats. Hepatogastroenterology 2005; 52: 1393-1397. (Pubitemid 41391000)
-
(2005)
Hepato-Gastroenterology
, vol.52
, Issue.65
, pp. 1393-1397
-
-
Oe, H.1
Kaido, T.2
Mori, A.3
Onodera, H.4
Imamura, M.5
-
66
-
-
0033027858
-
VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
-
DOI 10.1038/9467
-
Gerber HP, Vu TH, Ryan AM, Kowalski J, Werb Z, Ferrara N. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med 1999; 5: 623-628. (Pubitemid 29289424)
-
(1999)
Nature Medicine
, vol.5
, Issue.6
, pp. 623-628
-
-
Gerber, H.-P.1
Vu, T.H.2
Ryan, A.M.3
Kowalski, J.4
Werb, Z.5
Ferrara, N.6
-
67
-
-
0036166701
-
188
-
DOI 10.1016/S0925-4773(01)00601-3, PII S0925477301006013
-
Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D et al. Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Mech Dev 2002; 111: 61-73. (Pubitemid 34136979)
-
(2002)
Mechanisms of Development
, vol.111
, Issue.1-2
, pp. 61-73
-
-
Maes, C.1
Carmeliet, P.2
Moermans, K.3
Stockmans, I.4
Smets, N.5
Collen, D.6
Bouillon, R.7
Carmeliet, G.8
-
68
-
-
0037370325
-
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
-
DOI 10.1172/JCI200317423
-
Eremina V, Sood M, Haigh J, Nagy A, Lajoie G, Ferrara N et al. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 2003; 111: 707-716. (Pubitemid 36278589)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.5
, pp. 707-716
-
-
Eremina, V.1
Sood, M.2
Haigh, J.3
Nagy, A.4
Lajoie, G.5
Ferrara, N.6
Gerber, H.-P.7
Kikkawa, Y.8
Miner, J.H.9
Quaggin, S.E.10
-
69
-
-
0037373006
-
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction hypertension, and proteinuria in preeclampsia
-
DOI 10.1172/JCI200317189
-
Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 2003; 111: 649-658. (Pubitemid 36278583)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.5
, pp. 649-658
-
-
Maynard, S.E.1
Min, J.-Y.2
Merchan, J.3
Lim, K.-H.4
Li, J.5
Mondal, S.6
Libermann, T.A.7
Morgan, J.P.8
Sellke, F.W.9
Stillman, I.E.10
Epstein, F.H.11
Sukhatme, V.P.12
Karumanchi, S.A.13
-
70
-
-
39449111508
-
Neurovascular signalling defects in neurodegeneration
-
DOI 10.1038/nrn2336, PII NRN2336
-
Zacchigna S, Lambrechts D, Carmeliet P. Neurovascular signalling defects in neurodegeneration. Nat Rev Neurosci 2008; 9: 169-181. (Pubitemid 351272665)
-
(2008)
Nature Reviews Neuroscience
, vol.9
, Issue.3
, pp. 169-181
-
-
Zacchigna, S.1
Lambrechts, D.2
Carmeliet, P.3
-
71
-
-
0034502527
-
Vascular endothelial growth factor is a neurotrophic factor which stimulates axonal outgrowth through the flk-1 receptor
-
DOI 10.1046/j.0953-816X.2000.01326.x
-
Sondell M, Sundler F, Kanje M. Vascular endothelial growth factor is a neurotrophic factor which stimulates axonal outgrowth through the flk-1 receptor. Eur J Neurosci 2000; 12: 4243-4254. (Pubitemid 32037835)
-
(2000)
European Journal of Neuroscience
, vol.12
, Issue.12
, pp. 4243-4254
-
-
Sondell, M.1
Sundler, F.2
Kanje, M.3
-
72
-
-
0000481740
-
Vascular endothelial growth factor: Direct neuroprotective effect in in vitro ischemia
-
Jin KL, Mao XO, Greenberg DA. Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. Proc Natl Acad Sci USA 2000; 97: 10242-10247.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10242-10247
-
-
Jin, K.L.1
Mao, X.O.2
Greenberg, D.A.3
-
73
-
-
0032903416
-
Vascular, glial and neuronal effects of vascular endothelial growth factor in mesencephalic explant cultures
-
DOI 10.1016/S0306-4522(98)00540-5, PII S0306452298005405
-
Silverman WF, Krum JM, Mani N, Rosenstein JM. Vascular, glial and neuronal effects of vascular endothelial growth factor in mesencephalic explant cultures. Neuroscience 1999; 90: 1529-1541. (Pubitemid 29170166)
-
(1999)
Neuroscience
, vol.90
, Issue.4
, pp. 1529-1541
-
-
Silverman, W.F.1
Krum, J.M.2
Mani, N.3
Rosenstein, J.M.4
-
74
-
-
16644382257
-
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
-
DOI 10.1038/nn1360
-
Storkebaum E, Lambrechts D, Dewerchin M, Moreno-Murciano MP, Appelmans S, Oh H et al. Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS. Nat Neurosci 2005; 8: 85-92. (Pubitemid 41236736)
-
(2005)
Nature Neuroscience
, vol.8
, Issue.1
, pp. 85-92
-
-
Storkebaum, E.1
Lambrechts, D.2
Dewerchin, M.3
Moreno-Murciano, M.-P.4
Appelmans, S.5
Oh, H.6
Van Damme, P.7
Rutten, B.8
Man, W.9
De Mol, M.10
Wyns, S.11
Manka, D.12
Vermeulen, K.13
Van Den Bosch, L.14
Mertens, N.15
Schmitz, C.16
Robberecht, W.17
Conway, E.M.18
Collen, D.19
Moons, L.20
Carmeliet, P.21
more..
-
75
-
-
0035023584
-
Reversal of experimental diabetic neuropathy by VEGF gene transfer
-
Schratzberger P, Walter DH, Rittig K, Bahlmann FH, Pola R, Curry C et al. Reversal of experimental diabetic neuropathy by VEGF gene transfer. J Clin Invest 2001; 107: 1083-1092. (Pubitemid 32422905)
-
(2001)
Journal of Clinical Investigation
, vol.107
, Issue.9
, pp. 1083-1092
-
-
Schratzberger, P.1
Walter, D.H.2
Rittig, K.3
Bahlmann, F.H.4
Pola, R.5
Curry, C.6
Silver, M.7
Krainin, J.G.8
Weinberg, D.H.9
Ropper, A.H.10
Isner, J.M.11
-
76
-
-
0035839531
-
VEGF gene transfer for diabetic neuropathy
-
Isner JM, Ropper A, Hirst K. VEGF gene transfer for diabetic neuropathy. Hum Gene Ther 2001; 12: 1593-1594.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1593-1594
-
-
Isner, J.M.1
Ropper, A.2
Hirst, K.3
-
77
-
-
65649114702
-
Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: A randomized, double-blinded trial
-
Ropper AH, Gorson KC, Gooch CL, Weinberg DH, Pieczek A, Ware JH et al. Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: a randomized, double-blinded trial. Ann Neurol 2009; 65: 386-393.
-
(2009)
Ann Neurol
, vol.65
, pp. 386-393
-
-
Ropper, A.H.1
Gorson, K.C.2
Gooch, C.L.3
Weinberg, D.H.4
Pieczek, A.5
Ware, J.H.6
-
78
-
-
33751210105
-
VEGF at the neurovascular interface: Therapeutic implications for motor neuron disease
-
DOI 10.1016/j.bbadis.2006.04.005, PII S0925443906000792
-
Lambrechts D, Carmeliet P. VEGF at the neurovascular interface: therapeutic implications for motor neuron disease. Biochim Biophys Acta 2006; 1762: 1109-1121. (Pubitemid 44781175)
-
(2006)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1762
, Issue.11-12
, pp. 1109-1121
-
-
Lambrechts, D.1
Carmeliet, P.2
-
79
-
-
0034892980
-
Expression of vascular endothelial growth factor receptors in smooth muscle cells
-
DOI 10.1002/jcp.1121
-
Ishida A, Murray J, Saito Y, Kanthou C, Benzakour O, Shibuya M et al. Expression of vascular endothelial growth factor receptors in smooth muscle cells. J Cell Physiol 2001; 188: 359-368. (Pubitemid 32777178)
-
(2001)
Journal of Cellular Physiology
, vol.188
, Issue.3
, pp. 359-368
-
-
Ishida, A.1
Murray, J.2
Saito, Y.3
Kanthou, C.4
Benzakour, O.5
Shibuya, M.6
Wijelath, E.S.7
-
80
-
-
77954953944
-
Impaired autonomic regulation of resistance arteries in mice with low vascular endothelial growth factor or upon vascular endothelial growth factor trap delivery
-
Storkebaum E, Ruiz de Almodovar C, Meens M, Zacchigna S, Mazzone M, Vanhoutte G et al. Impaired autonomic regulation of resistance arteries in mice with low vascular endothelial growth factor or upon vascular endothelial growth factor trap delivery. Circulation 2010; 122: 273-281.
-
(2010)
Circulation
, vol.122
, pp. 273-281
-
-
Storkebaum, E.1
Ruiz De Almodovar, C.2
Meens, M.3
Zacchigna, S.4
Mazzone, M.5
Vanhoutte, G.6
-
81
-
-
7044235846
-
Vascular endothelial growth factor stimulates skeletal muscle regeneration in Vivo
-
DOI 10.1016/j.ymthe.2004.08.007, PII S1525001604013930
-
Arsic N, Zacchigna S, Zentilin L, Ramirez-Correa G, Pattarini L, Salvi A et al. Vascular endothelial growth factor stimulates skeletal muscle regeneration in vivo. Mol Ther 2004; 10: 844-854. (Pubitemid 39419911)
-
(2004)
Molecular Therapy
, vol.10
, Issue.5
, pp. 844-854
-
-
Arsic, N.1
Zacchigna, S.2
Zentilin, L.3
Ramirez-Correa, G.4
Pattarini, L.5
Salvi, A.6
Sinagra, G.7
Giacca, M.8
-
82
-
-
35948949462
-
VEGF overexpression via adeno-associated virus gene transfer promotes skeletal muscle regeneration and enhances muscle function in mdx mice
-
DOI 10.1096/fj.07-8459com
-
Messina S, Mazzeo A, Bitto A, Aguennouz M, Migliorato A, De Pasquale MG et al. VEGF overexpression via adeno-associated virus gene transfer promotes skeletal muscle regeneration and enhances muscle function in mdx mice. FASEB J 2007; 21: 3737-3746. (Pubitemid 350075161)
-
(2007)
FASEB Journal
, vol.21
, Issue.13
, pp. 3737-3746
-
-
Messina, S.1
Mazzeo, A.2
Bitto, A.3
Aguennouz, M.4
Migliorato, A.5
De Pasquale, M.G.6
Minutoli, L.7
Altavilla, D.8
Zentilin, L.9
Giacca, M.10
Squadrito, F.11
Vita, G.12
-
83
-
-
77955172099
-
Retinoic acid and VEGF delay smooth muscle relative to endothelial differentiation to coordinate inner and outer coronary vessel wall morphogenesis
-
Azambuja AP, Portillo-Sanchez V, Rodrigues MV, Omae SV, Schechtman D, Strauss BE et al. Retinoic acid and VEGF delay smooth muscle relative to endothelial differentiation to coordinate inner and outer coronary vessel wall morphogenesis. Circ Res 2010; 107: 204-216.
-
(2010)
Circ Res
, vol.107
, pp. 204-216
-
-
Azambuja, A.P.1
Portillo-Sanchez, V.2
Rodrigues, M.V.3
Omae, S.V.4
Schechtman, D.5
Strauss, B.E.6
-
84
-
-
33646128955
-
Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs
-
Ferrarini M, Arsic N, Recchia FA, Zentilin L, Zacchigna S, Xu X et al. Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs. Circ Res 2006; 98: 954-961.
-
(2006)
Circ Res
, vol.98
, pp. 954-961
-
-
Ferrarini, M.1
Arsic, N.2
Recchia, F.A.3
Zentilin, L.4
Zacchigna, S.5
Xu, X.6
-
85
-
-
77954214321
-
Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy
-
Pepe M, Mamdani M, Zentilin L, Csiszar A, Qanud K, Zacchigna S et al. Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy. Circ Res 2010; 106: 1893-1903.
-
(2010)
Circ Res
, vol.106
, pp. 1893-1903
-
-
Pepe, M.1
Mamdani, M.2
Zentilin, L.3
Csiszar, A.4
Qanud, K.5
Zacchigna, S.6
-
86
-
-
77952294182
-
Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction
-
Zentilin L, Puligadda U, Lionetti V, Zacchigna S, Collesi C, Pattarini L et al. Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction. FASEB J 2009; 24: 1467-1478.
-
(2009)
FASEB J
, vol.24
, pp. 1467-1478
-
-
Zentilin, L.1
Puligadda, U.2
Lionetti, V.3
Zacchigna, S.4
Collesi, C.5
Pattarini, L.6
-
87
-
-
45749092525
-
Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice
-
DOI 10.1172/JCI32832
-
Zacchigna S, Pattarini L, Zentilin L, Moimas S, Carrer A, Sinigaglia M et al. Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis. J Clin Invest 2008; 118: 2062-2075. (Pubitemid 351872326)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.6
, pp. 2062-2075
-
-
Zacchigna, S.1
Pattarini, L.2
Zentilin, L.3
Moimas, S.4
Carrer, A.5
Sinigaglia, M.6
Arsic, N.7
Tafuro, S.8
Sinagra, G.9
Giacca, M.10
-
88
-
-
78149281188
-
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
-
Bry M, Kivela R, Holopainen T, Anisimov A, Tammela T, Soronen J et al. Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation. Circulation 2010; 122: 1725-1733.
-
(2010)
Circulation
, vol.122
, pp. 1725-1733
-
-
Bry, M.1
Kivela, R.2
Holopainen, T.3
Anisimov, A.4
Tammela, T.5
Soronen, J.6
-
89
-
-
0028901624
-
Regulation of vascular endothelial growth factor in cardiac myocytes
-
Levy AP, Levy NS, Loscalzo J, Calderone A, Takahashi N, Yeo KT et al. Regulation of vascular endothelial growth factor in cardiac myocytes. Circ Res 1995; 76: 758-766.
-
(1995)
Circ Res
, vol.76
, pp. 758-766
-
-
Levy, A.P.1
Levy, N.S.2
Loscalzo, J.3
Calderone, A.4
Takahashi, N.5
Yeo, K.T.6
-
90
-
-
79955115054
-
VEGF attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation
-
Xu XH, Xu J, Xue L, Cao HL, Liu X, Chen YJ. VEGF attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation. J Cardiothorac Surg 2011; 6: 54.
-
(2011)
J Cardiothorac Surg
, vol.6
, pp. 54
-
-
Xu, X.H.1
Xu, J.2
Xue, L.3
Cao, H.L.4
Liu, X.5
Chen, Y.J.6
-
91
-
-
22344446893
-
VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heart
-
DOI 10.1101/gad.1319405
-
Rottbauer W, Just S, Wessels G, Trano N, Most P, Katus HA et al. VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heart. Genes Dev 2005; 19: 1624-1634. (Pubitemid 41003004)
-
(2005)
Genes and Development
, vol.19
, Issue.13
, pp. 1624-1634
-
-
Rottbauer, W.1
Just, S.2
Wessels, G.3
Trano, N.4
Most, P.5
Katus, H.A.6
Fishman, M.C.7
-
92
-
-
0037350079
-
Cardiac myofibroblasts: A novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR
-
DOI 10.1016/S0022-2828(03)00006-3
-
Chintalgattu V, Nair DM, Katwa LC. Cardiac myofibroblasts: a novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR. J Mol Cell Cardiol 2003; 35: 277-286. (Pubitemid 36379171)
-
(2003)
Journal of Molecular and Cellular Cardiology
, vol.35
, Issue.3
, pp. 277-286
-
-
Chintalgattu, V.1
Nair, D.M.2
Katwa, L.C.3
-
93
-
-
79959949081
-
VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart
-
Tang JM, Wang JN, Zhang L, Zheng F, Yang JY, Kong X et al. VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart. Cardiovasc Res 2011; 91: 402-411.
-
(2011)
Cardiovasc Res
, vol.91
, pp. 402-411
-
-
Tang, J.M.1
Wang, J.N.2
Zhang, L.3
Zheng, F.4
Yang, J.Y.5
Kong, X.6
-
94
-
-
70350002279
-
Adverse effects of anticancer agents that target the VEGF pathway
-
Chen HX, Cleck JN. Adverse effects of anticancer agents that target the VEGF pathway. Nat Rev Clin Oncol 2009; 6: 465-477.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 465-477
-
-
Chen, H.X.1
Cleck, J.N.2
-
95
-
-
67349287066
-
VEGF gene therapy fails to improve perfusion of ischemic myocardium in patients with advanced coronary disease: Results of the NORTHERN trial
-
Stewart DJ, Kutryk MJ, Fitchett D, Freeman M, Camack N, Su Y et al. VEGF gene therapy fails to improve perfusion of ischemic myocardium in patients with advanced coronary disease: results of the NORTHERN trial. Mol Ther 2009; 17: 1109-1115.
-
(2009)
Mol Ther
, vol.17
, pp. 1109-1115
-
-
Stewart, D.J.1
Kutryk, M.J.2
Fitchett, D.3
Freeman, M.4
Camack, N.5
Su, Y.6
|