Vasa vasorum anti-angiogenesis through H2O2, HIF-1α, NF-κB, and iNOS inhibition by mangosteen pericarp ethanolic extract (Garcinia mangostana Linn) in hypercholesterol-diet-given Rattus norvegicus Wistar strain

Vascular Health and Risk Management

Volumn 10, Issue , 2014, Pages 523-531

  Wihastuti, Titin Andri ^a   Sargowo, Djanggan ^a   Tjokroprawiro, Askandar ^b   Permatasari, Nur ^a   Widodo, Mohammad Aris ^a   Soeharto, Setyowati ^a  

^a BRAWIJAYA UNIVERSITY   (Indonesia)

^b AIRLANGGA UNIVERSITY   (Indonesia)

Author keywords

HIF 1 ; Hypercholesterol; Mangosteen pericarp ethanolic extract; NF B; Vasa vasorum angiogenesis

Indexed keywords

ALCOHOL; ANGIOGENESIS INHIBITOR; GARCINIA MANGOSTANA EXTRACT; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; PLANT EXTRACT; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1; CHOLESTEROL INTAKE; HIF1A PROTEIN, RAT; NOS2 PROTEIN, RAT; SOLVENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; AORTA MEDIA; ARTICLE; CHOLESTEROL INTAKE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENZYME INHIBITION; EXPERIMENTAL STUDY; GARCINIA MANGOSTANA; HYPERCHOLESTEROLEMIA; IMMUNOFLUORESCENCE TEST; IN VIVO STUDY; MALE; NONHUMAN; PERICARP; RAT; RATTUS NORVEGICUS; SMOOTH MUSCLE FIBER; STAINING; TISSUE LEVEL; VASA VASORUM; WISTAR RAT; ANIMAL; AORTIC DISEASES; ATHEROSCLEROSIS; CHEMISTRY; DISEASE MODEL; DOWN REGULATION; DRUG EFFECTS; ISOLATION AND PURIFICATION; LIPID DIET; MEDICINAL PLANT; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PHYTOTHERAPY; SIGNAL TRANSDUCTION;

ANGIOGENESIS INHIBITORS; ANIMALS; AORTIC DISEASES; ATHEROSCLEROSIS; CHOLESTEROL, DIETARY; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ETHANOL; GARCINIA MANGOSTANA; HYDROGEN PEROXIDE; HYPERCHOLESTEROLEMIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; NEOVASCULARIZATION, PATHOLOGIC; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS, WISTAR; SIGNAL TRANSDUCTION; SOLVENTS; VASA VASORUM;

EID: 84907312920     PISSN: 11766344     EISSN: 11782048     Source Type: Journal    
DOI: 10.2147/VHRM.S61736     Document Type: Article

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