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Volumn 85, Issue , 2016, Pages 5-34

Dietary Protein, Metabolism, and Aging

Author keywords

Aging; Anabolism; Dietary restriction; Macronutrients; Nutrient sensing signaling; Protein and amino acid requirement

Indexed keywords

AMINO ACID; BIOLOGICAL MARKER; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN; EIF2AK4 PROTEIN, HUMAN; INITIATION FACTOR 2; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PROTEIN INTAKE; PROTEIN SERINE THREONINE KINASE; SOMATOMEDIN C; TARGET OF RAPAMYCIN KINASE;

EID: 84974691666     PISSN: 00664154     EISSN: 15454509     Source Type: Book Series    
DOI: 10.1146/annurev-biochem-060815-014422     Document Type: Article
Times cited : (119)

References (150)
  • 1
    • 84875693632 scopus 로고    scopus 로고
    • Nature via nurture: Effect of diet on health, obesity, and safety assessment
    • Keenan KP, Wallig MA, Haschek WM. 2013. Nature via nurture: effect of diet on health, obesity, and safety assessment. Toxicol. Pathol. 41:190-209
    • (2013) Toxicol. Pathol. , vol.41 , pp. 190-209
    • Keenan, K.P.1    Wallig, M.A.2    Haschek, W.M.3
  • 3
    • 84895765028 scopus 로고    scopus 로고
    • The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice
    • Solon-Biet SM, McMahon AC, Ballard WO, Ruohonen K, Wu LE, et al. 2014. The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed micE. Cell Metab. 19:418-30
    • (2014) Cell Metab. , vol.19 , pp. 418-430
    • Solon-Biet, S.M.1    McMahon, A.C.2    Ballard, W.O.3    Ruohonen, K.4    Wu, L.E.5
  • 5
    • 84925852614 scopus 로고    scopus 로고
    • Promoting health and longevity through diet: From model organisms to humans
    • Fontana L, Partridge L. 2015. Promoting health and longevity through diet: from model organisms to humans. Cell 161:106-18
    • (2015) Cell , vol.161 , pp. 106-118
    • Fontana, L.1    Partridge, L.2
  • 7
    • 22744434107 scopus 로고    scopus 로고
    • Calories do not explain extension of life span by dietary restriction in Drosophila
    • Mair W, Piper MDW, Partridge L. 2005. Calories do not explain extension of life span by dietary restriction in Drosophila. PLOS Biol. 3:e223
    • (2005) PLOS Biol. , vol.3 , pp. e223
    • Mair, W.1    Piper, M.D.W.2    Partridge, L.3
  • 8
    • 72949117234 scopus 로고    scopus 로고
    • Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
    • Grandison RC, Piper MDW, Partridge L. 2009. Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Nature 462:1061-64
    • (2009) Nature , vol.462 , pp. 1061-1064
    • Grandison, R.C.1    Piper, M.D.W.2    Partridge, L.3
  • 9
    • 0023816160 scopus 로고
    • The effect of low protein-high dextrin diet and subsequent food restriction upon life prolongation in Fischer 344 male rats
    • Horáková M, Deyl Z, Hausmann J, Macek K. 1988. The effect of low protein-high dextrin diet and subsequent food restriction upon life prolongation in Fischer 344 male rats. Mech. Ageing Dev. 45:1-7
    • (1988) Mech. Ageing Dev. , vol.45 , pp. 1-7
    • Horáková, M.1    Deyl, Z.2    Hausmann, J.3    Macek, K.4
  • 10
    • 84860890706 scopus 로고    scopus 로고
    • Comparative and meta-analytic insights into life extension via dietary restriction
    • Nakagawa S, Lagisz M, Hector KL, Spencer HG. 2012. Comparative and meta-analytic insights into life extension via dietary restriction. Aging Cell 11:401-9
    • (2012) Aging Cell , vol.11 , pp. 401-409
    • Nakagawa, S.1    Lagisz, M.2    Hector, K.L.3    Spencer, H.G.4
  • 11
    • 84927697295 scopus 로고    scopus 로고
    • Protein and amino acid restriction, aging and disease: From yeast to humans
    • Mirzaei H, Suarez JA, Longo VD. 2014. Protein and amino acid restriction, aging and disease: from yeast to humans. Trends Endocrinol. Metab. 25(11):558-66
    • (2014) Trends Endocrinol. Metab. , vol.25 , Issue.11 , pp. 558-566
    • Mirzaei, H.1    Suarez, J.A.2    Longo, V.D.3
  • 12
    • 84938268460 scopus 로고    scopus 로고
    • Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet
    • Douris N, Melman T, Pecherer JM, Pissios P, Flier JS, et al. 2015. Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet. Biochim. Biophys. Acta 10:2056-65
    • (2015) Biochim. Biophys. Acta , vol.10 , pp. 2056-2065
    • Douris, N.1    Melman, T.2    Pecherer, J.M.3    Pissios, P.4    Flier, J.S.5
  • 15
    • 84911002688 scopus 로고    scopus 로고
    • Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism
    • Shin AC, Fasshauer M, FilatovaN, Grundell LA, Zielinski E, et al. 2014. Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism. Cell Metab. 20:898-909
    • (2014) Cell Metab. , vol.20 , pp. 898-909
    • Shin, A.C.1    Fasshauer, M.2    Filatova, N.3    Grundell, L.A.4    Zielinski, E.5
  • 17
    • 84890215172 scopus 로고    scopus 로고
    • What are the roles of calorie restriction and diet quality in promoting healthy longevity?
    • Rizza W, Veronese N, Fontana L. 2014. What are the roles of calorie restriction and diet quality in promoting healthy longevity? Ageing Res. Rev. 13:38-45
    • (2014) Ageing Res. Rev. , vol.13 , pp. 38-45
    • Rizza, W.1    Veronese, N.2    Fontana, L.3
  • 18
    • 84937392878 scopus 로고    scopus 로고
    • A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan
    • Brandhorst S, Choi IY, Wei M, Cheng CW, Sedrakyan S, et al. 2015. A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan. Cell Metab. 22:86-99
    • (2015) Cell Metab. , vol.22 , pp. 86-99
    • Brandhorst, S.1    Choi, I.Y.2    Wei, M.3    Cheng, C.W.4    Sedrakyan, S.5
  • 19
    • 84920995923 scopus 로고    scopus 로고
    • Endogenous hydrogen sulfide production is essential for dietary restriction benefits
    • Hine C, Harputlugil E, Zhang Y, Ruckenstuhl C, Lee BC, et al. 2015. Endogenous hydrogen sulfide production is essential for dietary restriction benefits. Cell 160:132-44
    • (2015) Cell , vol.160 , pp. 132-144
    • Hine, C.1    Harputlugil, E.2    Zhang, Y.3    Ruckenstuhl, C.4    Lee, B.C.5
  • 21
    • 84878910100 scopus 로고    scopus 로고
    • Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model
    • Parrella E, Maxim T, Maialetti F, Zhang L, Wan J, et al. 2013. Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model. Aging Cell 12:257-68
    • (2013) Aging Cell , vol.12 , pp. 257-268
    • Parrella, E.1    Maxim, T.2    Maialetti, F.3    Zhang, L.4    Wan, J.5
  • 23
    • 38449112372 scopus 로고    scopus 로고
    • Role of dietary proteins and amino acids in the pathogenesis of insulin resistance
    • Tremblay F, Lavigne C, Jacques H, Marette A. 2007. Role of dietary proteins and amino acids in the pathogenesis of insulin resistance. Annu. Rev. Nutr. 27:293-310
    • (2007) Annu. Rev. Nutr. , vol.27 , pp. 293-310
    • Tremblay, F.1    Lavigne, C.2    Jacques, H.3    Marette, A.4
  • 25
    • 0014824538 scopus 로고
    • Effects of ingestion of disproportionate amounts of amino acids
    • Harper AE, Benevenga NJ, Wohlhueter RM. 1970. Effects of ingestion of disproportionate amounts of amino acids. Physiol. Rev. 50:428-558
    • (1970) Physiol. Rev. , vol.50 , pp. 428-558
    • Harper, A.E.1    Benevenga, N.J.2    Wohlhueter, R.M.3
  • 26
    • 33749859865 scopus 로고    scopus 로고
    • Amino acid imbalance-biochemical mechanism and nutritional aspects
    • Park B-C. 2006. Amino acid imbalance-biochemical mechanism and nutritional aspects. Asian-Australas. J. Anim. Sci. 19:1361-68
    • (2006) Asian-Australas. J. Anim. Sci. , vol.19 , pp. 1361-1368
    • Park, B.-C.1
  • 27
    • 84971674653 scopus 로고
    • Washington, DC: National Academy Press. 4th ed., Board on Agriculture, National Research Council
    • Board on Agriculture, National Research Council. 1995. Nutrient Requirements of Laboratory Animals. Washington, DC: National Academy Press. 4th ed.
    • (1995) Nutrient Requirements of Laboratory Animals
  • 29
    • 84937150896 scopus 로고    scopus 로고
    • Dairy consumption and insulin resistance: The role of body fat, physical activity, and energy intake
    • Tucker LA, Erickson A, LeCheminant JD, Bailey BW. 2015. Dairy consumption and insulin resistance: The role of body fat, physical activity, and energy intake. J. Diabetes Res. 2015:206959
    • (2015) J. Diabetes Res. , vol.2015 , pp. 206959
    • Tucker, L.A.1    Erickson, A.2    LeCheminant, J.D.3    Bailey, B.W.4
  • 31
    • 38949089641 scopus 로고
    • Interpretation of amino acid requirement data according to the Law of Diminishing Returns
    • Almquist HJ. 1953. Interpretation of amino acid requirement data according to the Law of Diminishing Returns. Arch. Biochem. Biophys. 44:245-47
    • (1953) Arch. Biochem. Biophys. , vol.44 , pp. 245-247
    • Almquist, H.J.1
  • 32
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of life span and upon the ultimate body size
    • McCay CM, Crowell MF, Maynard LA. 1935. The effect of retarded growth upon the length of life span and upon the ultimate body size. J. Nutr. 10:63-79
    • (1935) J. Nutr. , vol.10 , pp. 63-79
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 33
    • 0242539698 scopus 로고    scopus 로고
    • The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling
    • JüngerMA, Rintelen F, Stocker H, Wasserman JD, VéghM, et al. 2003. The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J. Biol. 2:20
    • (2003) J. Biol. , vol.2 , pp. 20
    • Jünger, M.A.1    Rintelen, F.2    Stocker, H.3    Wasserman, J.D.4    Végh, M.5
  • 34
    • 0022502850 scopus 로고
    • Influence of dietary protein restriction on cell number, cell size and growth of mouse organs during the course of aging
    • Enesco HE, Samborsky J. 1986. Influence of dietary protein restriction on cell number, cell size and growth of mouse organs during the course of aging. Arch. Gerontol. Geriatr. 5:221-33
    • (1986) Arch. Gerontol. Geriatr. , vol.5 , pp. 221-233
    • Enesco, H.E.1    Samborsky, J.2
  • 35
    • 0013056730 scopus 로고    scopus 로고
    • Big mice die young: Early life body weight predicts longevity in genetically heterogeneous mice
    • Miller RA, Harper JM, Galecki A, Burke DT. 2002. Big mice die young: Early life body weight predicts longevity in genetically heterogeneous mice. Aging Cell 1:22-29
    • (2002) Aging Cell , vol.1 , pp. 22-29
    • Miller, R.A.1    Harper, J.M.2    Galecki, A.3    Burke, D.T.4
  • 37
    • 0036358167 scopus 로고    scopus 로고
    • Growth negatively impacts the life span of mammals
    • Rollo CD. 2002. Growth negatively impacts the life span of mammals. Evol. Dev. 4:55-61
    • (2002) Evol. Dev. , vol.4 , pp. 55-61
    • Rollo, C.D.1
  • 38
    • 84863323282 scopus 로고    scopus 로고
    • Healthy aging: Is smaller better?
    • Bartke A. 2012. Healthy aging: Is smaller better? Gerontology 58:337-43
    • (2012) Gerontology , vol.58 , pp. 337-343
    • Bartke, A.1
  • 39
    • 13944282128 scopus 로고    scopus 로고
    • Sex and death: What is the connection?
    • Partridge L, Gems D, Withers DJ. 2005. Sex and death: What is the connection? Cell 120:461-72
    • (2005) Cell , vol.120 , pp. 461-472
    • Partridge, L.1    Gems, D.2    Withers, D.J.3
  • 40
    • 39449084386 scopus 로고    scopus 로고
    • Use of stable isotopes to examine how dietary restriction extends Drosophila lifespan
    • O'Brien DM, Kyung-Jin M, Larsen T, Tatar M. 2008. Use of stable isotopes to examine how dietary restriction extends Drosophila lifespan. Curr. Biol. 18:R155-56
    • (2008) Curr. Biol. , vol.18 , pp. R155-R156
    • O'Brien, D.M.1    Kyung-Jin, M.2    Larsen, T.3    Tatar, M.4
  • 41
    • 84876207849 scopus 로고    scopus 로고
    • Reproductive capability is associated with lifespan and cause of death in companion dogs
    • Hoffman JM, Creevy KE, Promislow DEL. 2013. Reproductive capability is associated with lifespan and cause of death in companion dogs. PLOS ONE 8:e61082
    • (2013) PLOS ONE , vol.8 , pp. e61082
    • Hoffman, J.M.1    Creevy, K.E.2    Promislow, D.E.L.3
  • 43
    • 79958029524 scopus 로고    scopus 로고
    • Dietary proteins as determinants of metabolic and physiologic functions of the gastrointestinal tract
    • Jahan-Mihan A, Luhovyy BL, El Khoury D, Anderson GH. 2011. Dietary proteins as determinants of metabolic and physiologic functions of the gastrointestinal tract. Nutrients 3:574-603
    • (2011) Nutrients , vol.3 , pp. 574-603
    • Jahan-Mihan, A.1    Luhovyy, B.L.2    El Khoury, D.3    Anderson, G.H.4
  • 44
    • 84868109768 scopus 로고    scopus 로고
    • Available versus digestible dietary amino acids
    • Rutherfurd SM, Moughan PJ. 2012. Available versus digestible dietary amino acids. Br. J. Nutr. 108:S298-305
    • (2012) Br. J. Nutr. , vol.108 , pp. S298-305
    • Rutherfurd, S.M.1    Moughan, P.J.2
  • 45
    • 38349170961 scopus 로고    scopus 로고
    • Amino acid transport acrossmammalian intestinal and renal epithelia
    • Bröer S. 2008. Amino acid transport acrossmammalian intestinal and renal epithelia. Physiol. Rev. 88:249-86
    • (2008) Physiol. Rev. , vol.88 , pp. 249-286
    • Bröer, S.1
  • 46
    • 84888356673 scopus 로고    scopus 로고
    • Amino acid profiles in term and preterm human milk through lactation: A systematic review
    • Zhang Z, Adelman AS, Rai D, Boettcher J, L? onnerdal B. 2013. Amino acid profiles in term and preterm human milk through lactation: A systematic review. Nutrients 5:4800-21
    • (2013) Nutrients , vol.5 , pp. 4800-4821
    • Zhang, Z.1    Adelman, A.S.2    Rai, D.3    Boettcher, J.4    Onnerdal B, L.5
  • 47
    • 84872291131 scopus 로고    scopus 로고
    • Intestinal luminal nitrogen metabolism: Role of the gut microbiota and consequences for the host
    • Davila A-M, Blachier F, Gotteland M, Andriamihaja M, Benetti PH, et al. 2013. Intestinal luminal nitrogen metabolism: role of the gut microbiota and consequences for the host. Pharmacol. Res. 68:95-107
    • (2013) Pharmacol. Res. , vol.68 , pp. 95-107
    • Davila, A.-M.1    Blachier, F.2    Gotteland, M.3    Andriamihaja, M.4    Benetti, P.H.5
  • 48
    • 27944495653 scopus 로고    scopus 로고
    • Utilization of essential amino acids synthesized in the intestinal microbiota of monogastric mammals
    • Metges CC, Petzke KJ. 2007. Utilization of essential amino acids synthesized in the intestinal microbiota of monogastric mammals. Br. J. Nutr. 94:621-22
    • (2007) Br. J. Nutr. , vol.94 , pp. 621-622
    • Metges, C.C.1    Petzke, K.J.2
  • 49
    • 62649151803 scopus 로고    scopus 로고
    • Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
    • Wikoff WR, Anfora AT, Liu J, Schultz PG, Lesley SA, et al. 2009. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. PNAS 106:3698-703
    • (2009) PNAS , vol.106 , pp. 3698-3703
    • Wikoff, W.R.1    Anfora, A.T.2    Liu, J.3    Schultz, P.G.4    Lesley, S.A.5
  • 51
    • 84880368918 scopus 로고    scopus 로고
    • Structural modulation of gut microbiota in life-long calorie-restricted mice
    • Zhang C, Li S, Yang L, Huang P, Li W, et al. 2013. Structural modulation of gut microbiota in life-long calorie-restricted mice. Nat. Commun. 4:1-10
    • (2013) Nat. Commun. , vol.4 , pp. 1-10
    • Zhang, C.1    Li, S.2    Yang, L.3    Huang, P.4    Li, W.5
  • 52
    • 80053618114 scopus 로고    scopus 로고
    • Linking long-term dietary patterns with gut microbial enterotypes
    • Wu GD, Chen J, Hoffmann C, Bittinger K, Chen YY, et al. 2011. Linking long-term dietary patterns with gut microbial enterotypes. Science 334:105-8
    • (2011) Science , vol.334 , pp. 105-108
    • Wu, G.D.1    Chen, J.2    Hoffmann, C.3    Bittinger, K.4    Chen, Y.Y.5
  • 54
    • 84940377140 scopus 로고    scopus 로고
    • Microbial endocrinology: The interplay between the microbiota and the endocrine system
    • Neuman H, Debelius JW, Knight R, Koren O. 2015. Microbial endocrinology: The interplay between the microbiota and the endocrine system. FEMS Microbiol. Rev. 39(4):509-21
    • (2015) FEMS Microbiol. Rev. , vol.39 , Issue.4 , pp. 509-521
    • Neuman, H.1    Debelius, J.W.2    Knight, R.3    Koren, O.4
  • 55
    • 33845438071 scopus 로고    scopus 로고
    • Measuring splanchnic amino acid metabolism in vivo using stable isotopic tracers
    • Stoll B, Burrin DG. 2006. Measuring splanchnic amino acid metabolism in vivo using stable isotopic tracers. J. Anim. Sci. 84:E60-72
    • (2006) J. Anim. Sci. , vol.84 , pp. E60-72
    • Stoll, B.1    Burrin, D.G.2
  • 56
    • 0002691980 scopus 로고
    • Amino acids and growth factors in a chemically defined medium for Drosophila
    • Hinton T, Noyes DT, Ellis J. 1951. Amino acids and growth factors in a chemically defined medium for Drosophila. Physiol. Zool. 24:335-53
    • (1951) Physiol. Zool. , vol.24 , pp. 335-353
    • Hinton, T.1    Noyes, D.T.2    Ellis, J.3
  • 57
    • 33646758588 scopus 로고    scopus 로고
    • The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans
    • Ball RO, Courtney-Martin G, Pencharz PB. 2006. The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans. J. Nutr. 136:1682S-93S
    • (2006) J. Nutr. , vol.136 , pp. 93S-1682S
    • Ball, R.O.1    Courtney-Martin, G.2    Pencharz, P.B.3
  • 60
    • 33847338780 scopus 로고    scopus 로고
    • Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice
    • Selman C, Kerrison ND, Corray A, Piper MD, Lingard SJ, et al. 2006. Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice. Physiol. Genom. 27(3):187-200
    • (2006) Physiol. Genom. , vol.27 , Issue.3 , pp. 187-200
    • Selman, C.1    Kerrison, N.D.2    Corray, A.3    Piper, M.D.4    Lingard, S.J.5
  • 61
    • 84879978139 scopus 로고    scopus 로고
    • Metabolic phenotype modulation by caloric restriction in a lifelong dog study
    • Richards SE, Wang Y, Claus SP, Lawler D, Kochhar S, et al. 2013. Metabolic phenotype modulation by caloric restriction in a lifelong dog study. J. Proteome Res. 12:3117-27
    • (2013) J. Proteome Res. , vol.12 , pp. 3117-3127
    • Richards, S.E.1    Wang, Y.2    Claus, S.P.3    Lawler, D.4    Kochhar, S.5
  • 64
    • 23944431858 scopus 로고    scopus 로고
    • Nutritional control of gene expression: How mammalian cells respond to amino acid limitation
    • Kilberg MS, Pan Y-X, Chen H, Leung-Pineda V. 2005. Nutritional control of gene expression: how mammalian cells respond to amino acid limitation. Annu. Rev. Nutr. 25:59-85
    • (2005) Annu. Rev. Nutr. , vol.25 , pp. 59-85
    • Kilberg, M.S.1    Pan, Y.-X.2    Chen, H.3    Leung-Pineda, V.4
  • 65
    • 84880836560 scopus 로고    scopus 로고
    • Minireview: Nutrient sensing by G proteincoupled receptors
    • Wauson EM, Lorente-Rodrguez A, Cobb MH. 2013. Minireview: nutrient sensing by G proteincoupled receptors. Mol. Endocrinol. 27:1188-97
    • (2013) Mol. Endocrinol. , vol.27 , pp. 1188-1197
    • Wauson, E.M.1    Lorente-Rodrguez, A.2    Cobb, M.H.3
  • 66
    • 84986915942 scopus 로고    scopus 로고
    • Membrane transporters for the special amino acid glutamine: Structure/function relationships and relevance to human health
    • Pochini L, Scalise M, Galluccio M, Indiveri C. 2014. Membrane transporters for the special amino acid glutamine: structure/function relationships and relevance to human health. Front. Chem. 2:61
    • (2014) Front. Chem. , vol.2 , pp. 61
    • Pochini, L.1    Scalise, M.2    Galluccio, M.3    Indiveri, C.4
  • 67
    • 59049087460 scopus 로고    scopus 로고
    • Bidirectional transport of amino acids regulates mTOR and autophagy
    • Nicklin P, Bergman P, Zhang B, Triantafellow E, Wang H, et al. 2009. Bidirectional transport of amino acids regulates mTOR and autophagy. Cell 136:521-34
    • (2009) Cell , vol.136 , pp. 521-534
    • Nicklin, P.1    Bergman, P.2    Zhang, B.3    Triantafellow, E.4    Wang, H.5
  • 68
    • 84888602564 scopus 로고    scopus 로고
    • The digestive tract of Drosophila melanogaster
    • Lemaitre B, Miguel-Aliaga I. 2013. The digestive tract of Drosophila melanogaster. Annu. Rev. Genet. 47:377-404
    • (2013) Annu. Rev. Genet. , vol.47 , pp. 377-404
    • Lemaitre, B.1    Miguel-Aliaga, I.2
  • 69
    • 37348999218 scopus 로고    scopus 로고
    • Modulation of longevity by environmental sensing
    • Libert S, Pletcher SD. 2007. Modulation of longevity by environmental sensing. Cell 131:1231-34
    • (2007) Cell , vol.131 , pp. 1231-1234
    • Libert, S.1    Pletcher, S.D.2
  • 70
    • 84893511547 scopus 로고    scopus 로고
    • Sensing of amino acids in a dopaminergic circuitry promotes rejection of an incomplete diet in Drosophila
    • Bjordal M, Arquier N, Kniazeff J, Pin JP, Leopold P. 2014. Sensing of amino acids in a dopaminergic circuitry promotes rejection of an incomplete diet in Drosophila. Cell 156:510-21
    • (2014) Cell , vol.156 , pp. 510-521
    • Bjordal, M.1    Arquier, N.2    Kniazeff, J.3    Pin, J.P.4    Leopold, P.5
  • 71
    • 36048985768 scopus 로고    scopus 로고
    • Mechanisms of food intake repression in indispensable amino acid deficiency
    • Gietzen DW, Hao S, Anthony TG. 2007. Mechanisms of food intake repression in indispensable amino acid deficiency. Annu. Rev. Nutr. 27:63-78
    • (2007) Annu. Rev. Nutr. , vol.27 , pp. 63-78
    • Gietzen, D.W.1    Hao, S.2    Anthony, T.G.3
  • 72
    • 77953530150 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the adaptation to amino acid limitation in mammals
    • Chaveroux C, Lambert-Langlais S, Cherasse Y, Averous J, Parry L, et al. 2010. Molecular mechanisms involved in the adaptation to amino acid limitation in mammals. Biochimie 92:736-45
    • (2010) Biochimie , vol.92 , pp. 736-745
    • Chaveroux, C.1    Lambert-Langlais, S.2    Cherasse, Y.3    Averous, J.4    Parry, L.5
  • 74
    • 84922789990 scopus 로고    scopus 로고
    • Nutrient-sensing mechanisms and pathways
    • Efeyan A, CombWC, Sabatini DM. 2015. Nutrient-sensing mechanisms and pathways. Nature 517:302-10
    • (2015) Nature , vol.517 , pp. 302-310
    • Efeyan, A.1    Comb, W.C.2    Sabatini, D.M.3
  • 75
    • 68849087185 scopus 로고    scopus 로고
    • EIF2?kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver
    • Dang Do AN, Kimball SR, Cavener DR, Jefferson LS. 2009. EIF2?kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver. Physiol. Genomics 38:328-41
    • (2009) Physiol. Genomics , vol.38 , pp. 328-341
    • Dang Do, A.N.1    Kimball, S.R.2    Cavener, D.R.3    Jefferson, L.S.4
  • 77
    • 84946834576 scopus 로고    scopus 로고
    • Re-examination of dietary amino acid sensing reveals aGCN2-independent mechanism
    • Leib DE, Zachary AK. 2015. Re-examination of dietary amino acid sensing reveals aGCN2-independent mechanism. Cell Rep. 13:1081-89
    • (2015) Cell Rep. , vol.13 , pp. 1081-1089
    • Leib, D.E.1    Zachary, A.K.2
  • 79
    • 84871405563 scopus 로고    scopus 로고
    • Brainstem nutrient sensing in the nucleus of the solitary tract inhibits feeding
    • Blouet C, Schwartz GJ. 2012. Brainstem nutrient sensing in the nucleus of the solitary tract inhibits feeding. Cell Metab. 16:579-87
    • (2012) Cell Metab. , vol.16 , pp. 579-587
    • Blouet, C.1    Schwartz, G.J.2
  • 80
    • 58449089596 scopus 로고    scopus 로고
    • Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways
    • Deval C, Chaveroux C, Maurin AC, Cherasse Y, Parry L, et al. 2009. Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways. FEBS J. 276:707-18
    • (2009) FEBS J. , vol.276 , pp. 707-718
    • Deval, C.1    Chaveroux, C.2    Maurin, A.C.3    Cherasse, Y.4    Parry, L.5
  • 81
    • 67349255891 scopus 로고    scopus 로고
    • Differential regulation of protein synthesis by amino acids and insulin in peripheral and visceral tissues of neonatal pigs
    • Suryawan A, O'Connor PMJ, Bush JA, Nguyen HV, Davis TA. 2009. Differential regulation of protein synthesis by amino acids and insulin in peripheral and visceral tissues of neonatal pigs. Amino Acids 37:97-104
    • (2009) Amino Acids , vol.37 , pp. 97-104
    • Suryawan, A.1    O'Connor, P.M.J.2    Bush, J.A.3    Nguyen, H.V.4    Davis, T.A.5
  • 82
    • 84872137308 scopus 로고    scopus 로고
    • Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies
    • Stenesen D, Suh JM, Seo J, Yu K, Lee KS, et al. 2013. Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies. CellMetab. 17:101-12
    • (2013) CellMetab. , vol.17 , pp. 101-112
    • Stenesen, D.1    Suh, J.M.2    Seo, J.3    Yu, K.4    Lee, K.S.5
  • 83
    • 72249111299 scopus 로고    scopus 로고
    • MTOR, AMPK, andGCN2 coordinate the adaptation of hepatic energy metabolic pathways in response to protein intake in the rat
    • ChotechuangN, Azzout-Marniche D, Bos C, Chaumontet C, Gausserès N, et al. 2009. mTOR, AMPK, andGCN2 coordinate the adaptation of hepatic energy metabolic pathways in response to protein intake in the rat. Am. J. Physiol. Endocrinol. Metab. 297:E1313-23
    • (2009) Am. J. Physiol. Endocrinol. Metab. , vol.297 , pp. E1313-E1323
    • Chotechuang, N.1    Azzout-Marniche, D.2    Bos, C.3    Chaumontet, C.4    Gausserès, N.5
  • 84
    • 0018897754 scopus 로고
    • Induction of threonine imbalance by dispensable amino acids: Relationships between tissue amino acids and diet in rats
    • Tews JK, Kim YW, Harper AE. 1980. Induction of threonine imbalance by dispensable amino acids: relationships between tissue amino acids and diet in rats. J. Nutr. 110:394-408
    • (1980) J. Nutr. , vol.110 , pp. 394-408
    • Tews, J.K.1    Kim, Y.W.2    Harper, A.E.3
  • 85
    • 0028071511 scopus 로고
    • Dietary threonine imbalance alters threonine dehydrogenase activity in isolated hepatic mitochondria of chicks and rats
    • Davis AJ, Austic RE. 1994. Dietary threonine imbalance alters threonine dehydrogenase activity in isolated hepatic mitochondria of chicks and rats. J. Nutr. 124:1667-77
    • (1994) J. Nutr. , vol.124 , pp. 1667-1677
    • Davis, A.J.1    Austic, R.E.2
  • 86
    • 67349279270 scopus 로고    scopus 로고
    • Specificity of amino acid regulated gene expression: Analysis of genes subjected to either complete or single amino acid deprivation
    • Palii SS, Kays CE, Deval C, Bruhat A, Fafournoux P, Kilberg MS. 2009. Specificity of amino acid regulated gene expression: Analysis of genes subjected to either complete or single amino acid deprivation. Amino Acids 37:79-88
    • (2009) Amino Acids , vol.37 , pp. 79-88
    • Palii, S.S.1    Kays, C.E.2    Deval, C.3    Bruhat, A.4    Fafournoux, P.5    Kilberg, M.S.6
  • 87
    • 0034536065 scopus 로고    scopus 로고
    • Dietary restriction of single essential amino acids reduces plasma insulin-like growth factor-I (IGF-I) but does not affect plasma IGF-binding protein-1 in rats
    • Takenaka A, Oki N, Takahashi SI, Noguchi T. 2000. Dietary restriction of single essential amino acids reduces plasma insulin-like growth factor-I (IGF-I) but does not affect plasma IGF-binding protein-1 in rats. J. Nutr. 130:2910-14
    • (2000) J. Nutr. , vol.130 , pp. 2910-2914
    • Takenaka, A.1    Oki, N.2    Takahashi, S.I.3    Noguchi, T.4
  • 88
  • 89
    • 34548634634 scopus 로고    scopus 로고
    • Transcriptional response to aging and caloric restriction in heart and adipose tissue
    • Linford NJ, Beyer RP, Gollahon K, Krajcik RA, Malloy VL, et al. 2007. Transcriptional response to aging and caloric restriction in heart and adipose tissue. Aging Cell 6:673-88
    • (2007) Aging Cell , vol.6 , pp. 673-688
    • Linford, N.J.1    Beyer, R.P.2    Gollahon, K.3    Krajcik, R.A.4    Malloy, V.L.5
  • 90
    • 84894212463 scopus 로고    scopus 로고
    • Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2
    • Demetriades C, Doumpas N, Teleman AA. 2014. Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2. Cell 156:786-99
    • (2014) Cell , vol.156 , pp. 786-799
    • Demetriades, C.1    Doumpas, N.2    Teleman, A.A.3
  • 91
    • 79959409830 scopus 로고    scopus 로고
    • Amino acid signaling in TOR activation
    • Kim J, Guan K-L. 2011. Amino acid signaling in TOR activation. Annu. Rev. Biochem. 80:1001-32
    • (2011) Annu. Rev. Biochem. , vol.80 , pp. 1001-1032
    • Kim, J.1    Guan, K.-L.2
  • 94
    • 84922743269 scopus 로고    scopus 로고
    • Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1
    • Wang S, Tsun Z-Y, Wolfson RL, Shen K, Wyant GA, et al. 2015. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. Science 347:188-94
    • (2015) Science , vol.347 , pp. 188-194
    • Wang, S.1    Tsun, Z.-Y.2    Wolfson, R.L.3    Shen, K.4    Wyant, G.A.5
  • 95
    • 84888200442 scopus 로고    scopus 로고
    • The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1
    • Tsun Z-Y, Bar-Peled L, Chantranupong L, Zoncu R, Wang T, et al. 2013. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1. Mol. Cell 52:495-505
    • (2013) Mol. Cell , vol.52 , pp. 495-505
    • Tsun, Z.-Y.1    Bar-Peled, L.2    Chantranupong, L.3    Zoncu, R.4    Wang, T.5
  • 97
    • 84922727084 scopus 로고    scopus 로고
    • Differential regulation of mTORC1 by leucine and glutamine
    • Jewell JL, Kim YC, Russell RC, Yu F-X, ParkWH, et al. 2015. Differential regulation of mTORC1 by leucine and glutamine. Science 347:194-98
    • (2015) Science , vol.347 , pp. 194-198
    • Jewell, J.L.1    Kim, Y.C.2    Russell, R.C.3    Yu, F.-X.4    Park, W.H.5
  • 98
    • 84859117806 scopus 로고    scopus 로고
    • Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity
    • Lamming DW, Ye L, Karajisto P, Golcalves MD, Saitoh M, et al. 2012. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. Science 335:1638-43
    • (2012) Science , vol.335 , pp. 1638-1643
    • Lamming, D.W.1    Ye, L.2    Karajisto, P.3    Golcalves, M.D.4    Saitoh, M.5
  • 99
    • 80055115885 scopus 로고    scopus 로고
    • Insulin resistance due to nutrient excess: Is it a consequence of AMPK downregulation?
    • Saha AK, Xu XJ, Balon TW, Brandon A, Kraegen EW, Ruderman NB. 2011. Insulin resistance due to nutrient excess: Is it a consequence of AMPK downregulation? Cell Cycle 10:3447-51
    • (2011) Cell Cycle , vol.10 , pp. 3447-3451
    • Saha, A.K.1    Xu, X.J.2    Balon, T.W.3    Brandon, A.4    Kraegen, E.W.5    Ruderman, N.B.6
  • 100
    • 84862777407 scopus 로고    scopus 로고
    • Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway
    • Han JM, Jeong SJ, Park MC, Kim G, Kwon NH, et al. 2012. Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway. Cell 149:410-24
    • (2012) Cell , vol.149 , pp. 410-424
    • Han, J.M.1    Jeong, S.J.2    Park, M.C.3    Kim, G.4    Kwon, N.H.5
  • 102
    • 84870718527 scopus 로고    scopus 로고
    • Molecular nutrition research: The modern way of performing nutritional science
    • Norheim F, Gjelstad IMF, Hjorth M, Vinknes KJ, Langleite TM, et al. 2012. Molecular nutrition research: The modern way of performing nutritional science. Nutrients 4:1898-944
    • (2012) Nutrients , vol.4 , pp. 1898-1944
    • Norheim, F.1    Gjelstad, I.M.F.2    Hjorth, M.3    Vinknes, K.J.4    Langleite, T.M.5
  • 104
    • 84872117698 scopus 로고    scopus 로고
    • Amino acids and peptides activate at least five members of the human bitter taste receptor family
    • Kohl S, Behrens M, Dunkel A, Hofmann T, Meyerhof W. 2013. Amino acids and peptides activate at least five members of the human bitter taste receptor family. J. Agric. Food Chem. 61:53-60
    • (2013) J. Agric. Food Chem. , vol.61 , pp. 53-60
    • Kohl, S.1    Behrens, M.2    Dunkel, A.3    Hofmann, T.4    Meyerhof, W.5
  • 106
    • 84922692543 scopus 로고    scopus 로고
    • Suppression of insulin production and secretion by a decretin hormone
    • Alfa RW, Park S, Skelly KR, Poffenberger G, Jain N, et al. 2015. Suppression of insulin production and secretion by a decretin hormonE. Cell Metab. 21:323-33
    • (2015) Cell Metab. , vol.21 , pp. 323-333
    • Alfa, R.W.1    Park, S.2    Skelly, K.R.3    Poffenberger, G.4    Jain, N.5
  • 107
    • 84933677558 scopus 로고    scopus 로고
    • Mice lacking neutral amino acid transporter B0AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control
    • Jiang Y, Rose AJ, Sijmonsma TP, Broer A, Pfenninger A, et al. 2015. Mice lacking neutral amino acid transporter B0AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control. Mol. Metab. 4:406-17
    • (2015) Mol. Metab. , vol.4 , pp. 406-417
    • Jiang, Y.1    Rose, A.J.2    Sijmonsma, T.P.3    Broer, A.4    Pfenninger, A.5
  • 109
    • 84887545370 scopus 로고    scopus 로고
    • Specific amino acids inhibit food intake via the area postrema or vagal afferents
    • Jordi J, Herzog B, Camargo SMR, Boyle CN, Lutz TA, Verrey F. 2013. Specific amino acids inhibit food intake via the area postrema or vagal afferents. J. Physiol. 591:5611-21
    • (2013) J. Physiol. , vol.591 , pp. 5611-5621
    • Jordi, J.1    Herzog, B.2    Camargo, S.M.R.3    Boyle, C.N.4    Lutz, T.A.5    Verrey, F.6
  • 111
    • 84924145639 scopus 로고    scopus 로고
    • Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans
    • Edwards C, Canfield J, Copes N, Brito A, Rehan M, et al. 2015. Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 16:8
    • (2015) BMC Genet. , vol.16 , pp. 8
    • Edwards, C.1    Canfield, J.2    Copes, N.3    Brito, A.4    Rehan, M.5
  • 112
    • 84866179190 scopus 로고    scopus 로고
    • Growth culture conditions and nutrient signaling modulating yeast chronological longevity
    • Santos J, Leao C, Sousa MJ. 2012. Growth culture conditions and nutrient signaling modulating yeast chronological longevity. Oxidative Med. Cell. Longev. 2012:10
    • (2012) Oxidative Med. Cell. Longev. , vol.2012 , pp. 10
    • Santos, J.1    Leao, C.2    Sousa, M.J.3
  • 114
    • 33644868345 scopus 로고    scopus 로고
    • New functions for amino acids: Effects on gene transcription and translation
    • Kimball SR, Jefferson LS. 2006. New functions for amino acids: effects on gene transcription and translation. Am. J. Clin. Nutr. 83:500S-7S
    • (2006) Am. J. Clin. Nutr. , vol.83 , pp. 7S-500S
    • Kimball, S.R.1    Jefferson, L.S.2
  • 115
    • 70549094335 scopus 로고    scopus 로고
    • GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent Lasparaginase
    • Bunpo P, Dudley A, Cundiff JK, Cavender DR, Wek RC, Anthony TG. 2009. GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent Lasparaginase. J. Biol. Chem. 284:32742-49
    • (2009) J. Biol. Chem. , vol.284 , pp. 32742-32749
    • Bunpo, P.1    Dudley, A.2    Cundiff, J.K.3    Cavender, D.R.4    Wek, R.C.5    Anthony, T.G.6
  • 116
    • 84883817838 scopus 로고    scopus 로고
    • The general control nonderepressible-2 kinase mediates stress response and longevity induced by target of rapamycin inactivation in Caenorhabditis elegans
    • Rousakis A, Vlassis A, Vlanti A, Patera S, Thireos G, Syntichaki P. 2013. The general control nonderepressible-2 kinase mediates stress response and longevity induced by target of rapamycin inactivation in Caenorhabditis elegans. Aging Cell 12:742-51
    • (2013) Aging Cell , vol.12 , pp. 742-751
    • Rousakis, A.1    Vlassis, A.2    Vlanti, A.3    Patera, S.4    Thireos, G.5    Syntichaki, P.6
  • 117
    • 84947914958 scopus 로고    scopus 로고
    • GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2
    • Ye J, Palm W, Peng M, King B, Lindsten T, et al. 2015. GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2. Genes Dev. 29:2331-36
    • (2015) Genes Dev. , vol.29 , pp. 2331-2336
    • Ye, J.1    Palm, W.2    Peng, M.3    King, B.4    Lindsten, T.5
  • 118
    • 78049502688 scopus 로고    scopus 로고
    • The acute effects of four protein meals on insulin, glucose, appetite and energy intake in lean men
    • Pal S, Ellis V. 2010. The acute effects of four protein meals on insulin, glucose, appetite and energy intake in lean men. Br. J. Nutr. 104:1241-48
    • (2010) Br. J. Nutr. , vol.104 , pp. 1241-1248
    • Pal, S.1    Ellis, V.2
  • 120
    • 0036790113 scopus 로고    scopus 로고
    • Modeling biochemical aspects of energymetabolism inmammals
    • vanMilgen J. 2002. Modeling biochemical aspects of energymetabolism inmammals. J. Nutr. 132:3195-202
    • (2002) J. Nutr. , vol.132 , pp. 3195-3202
    • VanMilgen, J.1
  • 121
    • 84903139148 scopus 로고    scopus 로고
    • The metabolite ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
    • Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, et al. 2014. The metabolite ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature 510(7505):397-401
    • (2014) Nature , vol.510 , Issue.7505 , pp. 397-401
    • Chin, R.M.1    Fu, X.2    Pai, M.Y.3    Vergnes, L.4    Hwang, H.5
  • 122
    • 77957661352 scopus 로고    scopus 로고
    • Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice
    • D'Antona G, Ragni M, Cardile A, Tedesco L, Dossena M, et al. 2010. Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged micE. Cell Metab. 12:362-72
    • (2010) Cell Metab. , vol.12 , pp. 362-372
    • D'Antona, G.1    Ragni, M.2    Cardile, A.3    Tedesco, L.4    Dossena, M.5
  • 123
    • 84904438541 scopus 로고    scopus 로고
    • Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer
    • Poff AM, Ari C, Arnold P, Seyfried TN, D'AgostinoDP. 2014. Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer. Int. J. Cancer 135:1711-20
    • (2014) Int. J. Cancer , vol.135 , pp. 1711-1720
    • Poff, A.M.1    Ari, C.2    Arnold, P.3    Seyfried, T.N.4    D'Agostino, D.P.5
  • 125
    • 84930966126 scopus 로고    scopus 로고
    • Reviewing the effects of l-leucine supplementation in the regulation of food intake, energy balance, and glucose homeostasis
    • Pedroso JAB, Zampieri TT, Donato J. 2015. Reviewing the effects of l-leucine supplementation in the regulation of food intake, energy balance, and glucose homeostasis. Nutrients 7:3914-37
    • (2015) Nutrients , vol.7 , pp. 3914-3937
    • Pedroso, J.A.B.1    Zampieri, T.T.2    Donato, J.3
  • 126
    • 84939942269 scopus 로고    scopus 로고
    • Effects of leucine-rich protein supplements on anthropometric parameter and muscle strength in the elderly: A systematic review and meta-analysis
    • Komar B, Schwingshackl L, Hoffmann G. 2015. Effects of leucine-rich protein supplements on anthropometric parameter and muscle strength in the elderly: A systematic review and meta-analysis. J. Nutr. Health Aging 19:437-46
    • (2015) J. Nutr. Health Aging , vol.19 , pp. 437-446
    • Komar, B.1    Schwingshackl, L.2    Hoffmann, G.3
  • 127
    • 84870441206 scopus 로고    scopus 로고
    • Biochemical and metabolic mechanisms by which dietary whey protein may combat obesity and type 2 diabetes
    • Jakubowicz D, Froy O. 2013. Biochemical and metabolic mechanisms by which dietary whey protein may combat obesity and type 2 diabetes. J. Nutr. Biochem. 24:1-5
    • (2013) J. Nutr. Biochem. , vol.24 , pp. 1-5
    • Jakubowicz, D.1    Froy, O.2
  • 128
    • 57749196739 scopus 로고    scopus 로고
    • The low-methionine content of vegan diets may make methionine restriction feasible as a life extension strategy
    • McCarty MF, Barroso-Aranda J, Contreras F. 2009. The low-methionine content of vegan diets may make methionine restriction feasible as a life extension strategy. Med. Hypotheses 72:125-28
    • (2009) Med. Hypotheses , vol.72 , pp. 125-128
    • McCarty, M.F.1    Barroso-Aranda, J.2    Contreras, F.3
  • 129
    • 84880912548 scopus 로고    scopus 로고
    • Milk is not just food but most likely a genetic transfection system activating mTORC1 signaling for postnatal growth
    • Melnik BC, John SM, SchmitzG. 2013. Milk is not just food but most likely a genetic transfection system activating mTORC1 signaling for postnatal growth. Nutr. J. 12:103
    • (2013) Nutr. J. , vol.12 , pp. 103
    • Melnik, B.C.1    John, S.M.2    Schmitz, G.3
  • 130
    • 84860439210 scopus 로고    scopus 로고
    • Interplay between lipids and branched-chain amino acids in development of insulin resistance
    • Newgard CB. 2012. Interplay between lipids and branched-chain amino acids in development of insulin resistancE. Cell Metab. 15:606-14
    • (2012) Cell Metab. , vol.15 , pp. 606-614
    • Newgard, C.B.1
  • 131
    • 84899680382 scopus 로고    scopus 로고
    • The Blue Zones: Areas of exceptional longevity around the world
    • Poulain M, Herm A, Pes G. 2013. The Blue Zones: Areas of exceptional longevity around the world. Vienna Yearb. Popul. Res. 11:87-180
    • (2013) Vienna Yearb. Popul. Res. , vol.11 , pp. 87-180
    • Poulain, M.1    Herm, A.2    Pes, G.3
  • 133
    • 80755148794 scopus 로고    scopus 로고
    • Adherence to the Mediterranean diet reduces mortality in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain)
    • Buckland G, Agudo A, Travier N, Huerta JM, Cirera L, et al. 2011. Adherence to the Mediterranean diet reduces mortality in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain). Br. J. Nutr. 106:1581-91
    • (2011) Br. J. Nutr. , vol.106 , pp. 1581-1591
    • Buckland, G.1    Agudo, A.2    Travier, N.3    Huerta, J.M.4    Cirera, L.5
  • 134
    • 84883763401 scopus 로고    scopus 로고
    • Dietary restriction extends lifespan in wild-derived populations of Drosophila melanogaster
    • Metaxakis A, Partridge L. 2013. Dietary restriction extends lifespan in wild-derived populations of Drosophila melanogaster. PLOS ONE 8:e74681
    • (2013) PLOS ONE , vol.8 , pp. e74681
    • Metaxakis, A.1    Partridge, L.2
  • 135
    • 76249097841 scopus 로고    scopus 로고
    • Genetic variation in the murine lifespan response to dietary restriction: From life extension to life shortening
    • Liao C-Y, Rikke BA, Johnson TE, Diaz V, Nelson JF. 2010. Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening. Aging Cell 9:92-95
    • (2010) Aging Cell , vol.9 , pp. 92-95
    • Liao, C.-Y.1    Rikke, B.A.2    Johnson, T.E.3    Diaz, V.4    Nelson, J.F.5
  • 136
    • 84907997113 scopus 로고    scopus 로고
    • Rapid identification of major-effect genes using the collaborative cross
    • Ram R, Mehta M, Balmer L, Gatti DM, Morahan G. 2014. Rapid identification of major-effect genes using the collaborative cross. Genetics 198:75-86
    • (2014) Genetics , vol.198 , pp. 75-86
    • Ram, R.1    Mehta, M.2    Balmer, L.3    Gatti, D.M.4    Morahan, G.5
  • 137
  • 138
    • 0037228809 scopus 로고    scopus 로고
    • Protein digestibility and quality in products containing antinutritional factors are adversely affected by old age in rats
    • GilaniGS, Sepehr E. 2003. Protein digestibility and quality in products containing antinutritional factors are adversely affected by old age in rats. J. Nutr. 133:220-25
    • (2003) J. Nutr. , vol.133 , pp. 220-225
    • Gilani, G.S.1    Sepehr, E.2
  • 139
    • 67649660052 scopus 로고    scopus 로고
    • Life-span extension in mice by preweaning food restriction and by methionine restriction in middle age
    • Sun L, Sadighi Akha AA, Miller RA, Harper JM. 2009. Life-span extension in mice by preweaning food restriction and by methionine restriction in middle age. J. Gerontol. A 64A:711-22
    • (2009) J. Gerontol. A , vol.64 A , pp. 711-722
    • Sun, L.1    Sadighi Akha, A.A.2    Miller, R.A.3    Harper, J.M.4
  • 140
    • 0842328994 scopus 로고    scopus 로고
    • Lifespan: Catch-up growth and obesity in male mice
    • Ozanne SE, Hales CN. 2004. Lifespan: catch-up growth and obesity in male mice. Nature 427:411-12
    • (2004) Nature , vol.427 , pp. 411-412
    • Ozanne, S.E.1    Hales, C.N.2
  • 141
    • 0017146712 scopus 로고
    • Amino acid requirements of the growing mouse
    • John AM, Bell JM. 1976. Amino acid requirements of the growing mouse. J. Nutr. 106:1361-67
    • (1976) J. Nutr. , vol.106 , pp. 1361-1367
    • John, A.M.1    Bell, J.M.2
  • 142
    • 0027295627 scopus 로고
    • Lowering effect of dietary milk-whey protein v. Casein on plasma and liver cholesterol concentrations in rats
    • Zhang X, Beynen AC. 1993. Lowering effect of dietary milk-whey protein v. casein on plasma and liver cholesterol concentrations in rats. Br. J. Nutr. 70:139-46
    • (1993) Br. J. Nutr. , vol.70 , pp. 139-146
    • Zhang, X.1    Beynen, A.C.2
  • 143
    • 0023908487 scopus 로고
    • Modulation of age-related hyperparathyroidism and senile bone loss in Fischer rats by soy protein and food restriction
    • Kalu DN, Masoro EJ, Yu BP, Hardin RR, Hollis BW. 1988. Modulation of age-related hyperparathyroidism and senile bone loss in Fischer rats by soy protein and food restriction. Endocrinology 122:1847-54
    • (1988) Endocrinology , vol.122 , pp. 1847-1854
    • Kalu, D.N.1    Masoro, E.J.2    Yu, B.P.3    Hardin, R.R.4    Hollis, B.W.5
  • 144
    • 79955505073 scopus 로고    scopus 로고
    • Dietary whey protein lowers the risk for metabolic disease in mice fed a high-fat diet
    • Shertzer HG, Woods SE, Krishan M, Genter MB, Pearson KJ. 2011. Dietary whey protein lowers the risk for metabolic disease in mice fed a high-fat diet. J. Nutr. 141:582-87
    • (2011) J. Nutr. , vol.141 , pp. 582-587
    • Shertzer, H.G.1    Woods, S.E.2    Krishan, M.3    Genter, M.B.4    Pearson, K.J.5
  • 145
    • 0024817818 scopus 로고
    • The influence of dietary whey protein on tissue glutathione and the diseases of aging
    • Bounous G, Gervais F, Amer V, Batist G, Gold P. 1989. The influence of dietary whey protein on tissue glutathione and the diseases of aging. Clin. Investig. Med. 12:343-49
    • (1989) Clin. Investig. Med. , vol.12 , pp. 343-349
    • Bounous, G.1    Gervais, F.2    Amer, V.3    Batist, G.4    Gold, P.5
  • 146
    • 66549097704 scopus 로고    scopus 로고
    • The association between diet and serum concentrations of IGF-1, IGFBP-1, IGFBP-2, and IGFBP-3 in the European Prospective Investigation into cancer and nutrition
    • Crowe FL, Key TJ, Allen NE, Appleby PN, Roddam A, et al. 2009. The association between diet and serum concentrations of IGF-1, IGFBP-1, IGFBP-2, and IGFBP-3 in the European Prospective Investigation into cancer and nutrition. Cancer Epidemiol. Biomark. Prev. 18:1333-40
    • (2009) Cancer Epidemiol. Biomark. Prev. , vol.18 , pp. 1333-1340
    • Crowe, F.L.1    Key, T.J.2    Allen, N.E.3    Appleby, P.N.4    Roddam, A.5
  • 147
    • 84870712685 scopus 로고    scopus 로고
    • Whey protein and essential amino acids promote the reduction of adipose tissue and increasedmuscle protein synthesis during caloric restrictioninduced weight loss in elderly, obese individuals
    • Coker RH, Miller S, Schutzler S, Deutz N, Wolfe RR. 2012. Whey protein and essential amino acids promote the reduction of adipose tissue and increasedmuscle protein synthesis during caloric restrictioninduced weight loss in elderly, obese individuals. Nutr. J. 11:105
    • (2012) Nutr. J. , vol.11 , pp. 105
    • Coker, R.H.1    Miller, S.2    Schutzler, S.3    Deutz, N.4    Wolfe, R.R.5
  • 148
    • 0034477619 scopus 로고    scopus 로고
    • Protein nutrition and insulin-like growth factor system
    • Noguchi T. 2000. Protein nutrition and insulin-like growth factor system. Br. J. Nutr. 84:S241-44
    • (2000) Br. J. Nutr. , vol.84 , pp. S241-S244
    • Noguchi, T.1
  • 149
    • 84873395608 scopus 로고    scopus 로고
    • A scientific review of the reported effects of vegan nutrition on the occurrence and prevalence of cancer and cardiovascular disease
    • O'Neill B. 2010. A scientific review of the reported effects of vegan nutrition on the occurrence and prevalence of cancer and cardiovascular disease. Biosci. Horiz. 3:197-212
    • (2010) Biosci. Horiz. , vol.3 , pp. 197-212
    • O'Neill, B.1


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