Protein restriction cycles reduce IGF-1 and phosphorylated tau, and improve behavioral performance in an Alzheimer's disease mouse model

Aging Cell

Volumn 12, Issue 2, 2013, Pages 257-268

  Parrella, Edoardo ^a   Maxim, Tom ^a   Maialetti, Francesca ^b   Zhang, Lu ^a   Wan, Junxiang ^a   Wei, Min ^a   Cohen, Pinchas ^a   Fontana, Luigi ^c,d,e   Longo, Valter D ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF SALERNO   (Italy)

^e CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

Aging; Alzheimer; IGF 1; IGFBP 1; Protein restriction; Tau

Indexed keywords

GLUCOSE; GROWTH FACTOR; NONESSENTIAL AMINO ACID; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; TAU PROTEIN;

AGING; ALZHEIMER DISEASE; AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; BODY WEIGHT; CALORIC INTAKE; CALORIC RESTRICTION; CELL COUNT; COGNITIVE DEFECT; CONTROLLED STUDY; DIET RESTRICTION; ENCEPHALITIS; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAZE TEST; MICROGLIA; MOUSE; NEUROPATHOLOGY; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN RESTRICTION; SPATIAL MEMORY; WORKING MEMORY;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; COGNITION; DIET, PROTEIN-RESTRICTED; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HIPPOCAMPUS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; PHOSPHORYLATION; TAU PROTEINS;

ANIMALIA; MUS; RODENTIA;

EID: 84878910100     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12049     Document Type: Article

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