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Volumn 351, Issue 6268, 2016, Pages 53-58
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Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway
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Author keywords
[No Author keywords available]
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Indexed keywords
FUNCTIONAL GROUP;
GATOR 2 PROTEIN;
ISOLEUCINE;
LEUCINE;
MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1;
METHIONINE;
PROTEIN;
SESTRIN 2 PROTEIN;
UNCLASSIFIED DRUG;
MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1;
MULTIPROTEIN COMPLEX;
NUCLEAR PROTEIN;
PROTEIN BINDING;
SESN2 PROTEIN, HUMAN;
TARGET OF RAPAMYCIN KINASE;
AMINO ACID;
CELL ORGANELLE;
CRYSTAL STRUCTURE;
EUKARYOTE;
MUTATION;
PROTEIN;
ARTICLE;
BINDING AFFINITY;
BINDING SITE;
CONCENTRATION PROCESS;
CONFORMATIONAL TRANSITION;
CRYSTAL STRUCTURE;
ENZYME ACTIVATION;
ENZYME MECHANISM;
GENE MUTATION;
HUMAN;
HYDROPHOBICITY;
MOLECULAR RECOGNITION;
PRIORITY JOURNAL;
PROTEIN BINDING;
PROTEIN INTERACTION;
PROTEIN STRUCTURE;
SENSITIVITY ANALYSIS;
SIGNAL TRANSDUCTION;
AMINO ACID SEQUENCE;
CHEMISTRY;
GENETICS;
HEK293 CELL LINE;
METABOLISM;
MOLECULAR GENETICS;
MUTATION;
PROTEIN SECONDARY STRUCTURE;
PROTEIN TERTIARY STRUCTURE;
X RAY CRYSTALLOGRAPHY;
EUKARYOTA;
AMINO ACID SEQUENCE;
BINDING SITES;
CRYSTALLOGRAPHY, X-RAY;
HEK293 CELLS;
HUMANS;
LEUCINE;
METABOLIC NETWORKS AND PATHWAYS;
MOLECULAR SEQUENCE DATA;
MULTIPROTEIN COMPLEXES;
MUTATION;
NUCLEAR PROTEINS;
PROTEIN BINDING;
PROTEIN STRUCTURE, SECONDARY;
PROTEIN STRUCTURE, TERTIARY;
TOR SERINE-THREONINE KINASES;
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EID: 84952898511
PISSN: 00368075
EISSN: 10959203
Source Type: Journal
DOI: 10.1126/science.aad2087 Document Type: Article |
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Times cited : (341)
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References (29)
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