The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice

Cell Metabolism

Volumn 19, Issue 3, 2014, Pages 418-430

  Solon Biet, Samantha M ^a   McMahon, Aisling C ^a   Ballard, J William O ^b   Ruohonen, Kari ^c   Wu, Lindsay E ^b   Cogger, Victoria C ^a   Warren, Alessandra ^a   Huang, Xin ^a   Pichaud, Nicolas ^b   Melvin, Richard G ^d   Gokarn, Rahul ^a   Khalil, Mamdouh ^a   Turner, Nigel ^b   Cooney, Gregory J ^b   Sinclair, David A ^b,e   Raubenheimer, David ^a,f   Le Couteur, David G ^a   Simpson, Stephen J ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c CARGILL INC   (United States)

^d UNIVERSITY OF HELSINKI   (Finland)

^e HARVARD MEDICAL SCHOOL   (United States)

^f MASSEY UNIVERSITY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; ASPARAGINE; ASPARTIC ACID; BRANCHED CHAIN AMINO ACID; CITRULLINE; CYSTEINE; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; GLYCINE; HISTIDINE; ISOLEUCINE; LEUCINE; LYSINE; MAMMALIAN TARGET OF RAPAMYCIN; METHIONINE; ORNITHINE; PHENYLALANINE; PROLINE; SERINE; TAURINE; THREONINE; TRYPTOPHAN; TYROSINE; VALINE; CARBOHYDRATE; FAT; GLUCOSE; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PROTEIN;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CALORIC RESTRICTION; CARBOHYDRATE INTAKE; CARDIOMETABOLIC RISK; CONTROLLED STUDY; DILUTION; FAT INTAKE; FEMALE; FOOD INTAKE; LIFESPAN; LONGEVITY; MACRONUTRIENT; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DIET; PROTEIN INTAKE; BODY FAT; CARBOHYDRATE ANALYSIS; FOOD COMPOSITION; HEALTH; LEAN BODY WEIGHT; LIFE EXPECTANCY; LIVER MITOCHONDRION; MITOCHONDRIAL RESPIRATION; NUTRIENT AVAILABILITY; NUTRIENT CONCENTRATION; PROTEIN CONTENT;

MUS;

AGING; AMINO ACIDS, BRANCHED-CHAIN; ANIMALS; BLOOD PRESSURE; BODY COMPOSITION; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; DIET; ENERGY INTAKE; GLUCOSE; GLUCOSE INTOLERANCE; INSULIN; KAPLAN-MEIER ESTIMATE; LEPTIN; LIVER; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; TOR SERINE-THREONINE KINASES;

EID: 84895765028     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2014.02.009     Document Type: Article

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