메뉴 건너뛰기




Volumn 73, Issue 13, 2016, Pages 2511-2530

Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders

Author keywords

Autism; CREB; Dyskinesia; GSK3; Lithium; Nrf2; Suicide

Indexed keywords

1 (5 CHLORO 2,4 DIMETHOXYPHENYL) 3 (5 METHYL 3 ISOXAZOLYL)UREA; 3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; ABT 107; ACETYLCHOLINE; AQW 051; BRADANICLINE; BUNGAROTOXIN RECEPTOR; BUNGAROTOXIN RECEPTOR STIMULATING AGENT; CHOLINE; ENCENICLINE; GALANTAMINE; GENISTEIN; GLUCOCORTICOID; JNJ 39393406; LITHIUM SALT; MINOCYCLINE; NICOTINIC AGENT; ONDANSETRON; RG 3487; TROPISETRON; UNCLASSIFIED DRUG;

EID: 84961176521     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-016-2175-4     Document Type: Review
Times cited : (142)

References (256)
  • 1
    • 0034945151 scopus 로고    scopus 로고
    • Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia
    • COI: 1:CAS:528:DC%2BD3MXltlOjtb0%3D, PID: 11470559
    • Marutle A, Zhang X, Court J, Piggott M, Johnson M, Perry R, Perry E, Nordberg A (2001) Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia. J Chem Neuroanat 22:115–126
    • (2001) J Chem Neuroanat , vol.22 , pp. 115-126
    • Marutle, A.1    Zhang, X.2    Court, J.3    Piggott, M.4    Johnson, M.5    Perry, R.6    Perry, E.7    Nordberg, A.8
  • 2
    • 84872295116 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors: from basic science to therapeutics
    • COI: 1:CAS:528:DC%2BC38Xhs12gtbbF, PID: 22925690
    • Hurst R, Rollema H, Bertrand D (2013) Nicotinic acetylcholine receptors: from basic science to therapeutics. Pharmacol Ther 137:22–54. doi:10.1016/j.pharmthera.2012.08.012
    • (2013) Pharmacol Ther , vol.137 , pp. 22-54
    • Hurst, R.1    Rollema, H.2    Bertrand, D.3
  • 3
    • 84922216722 scopus 로고    scopus 로고
    • Nicotinic ACh receptors as therapeutic targets in CNS disorders
    • COI: 1:CAS:528:DC%2BC2MXhslylug%3D%3D, PID: 25639674
    • Dineley KT, Pandya AA, Yakel JL (2015) Nicotinic ACh receptors as therapeutic targets in CNS disorders. Trends Pharmacol Sci 36:96–108. doi:10.1016/j.tips.2014.12.002
    • (2015) Trends Pharmacol Sci , vol.36 , pp. 96-108
    • Dineley, K.T.1    Pandya, A.A.2    Yakel, J.L.3
  • 4
    • 84924503662 scopus 로고    scopus 로고
    • Functional alpha7 nicotinic receptors are expressed on immature granule cells of the postnatal dentate gyrus
    • COI: 1:CAS:528:DC%2BC2MXmt12qtw%3D%3D, PID: 25553616
    • John D, Shelukhina I, Yanagawa Y, Deuchars J, Henderson Z (2015) Functional alpha7 nicotinic receptors are expressed on immature granule cells of the postnatal dentate gyrus. Brain Res 1601:15–30. doi:10.1016/j.brainres.2014.12.041
    • (2015) Brain Res , vol.1601 , pp. 15-30
    • John, D.1    Shelukhina, I.2    Yanagawa, Y.3    Deuchars, J.4    Henderson, Z.5
  • 5
    • 84865140660 scopus 로고    scopus 로고
    • Functional alpha7 nicotinic ACh receptors on astrocytes in rat hippocampal CA1 slices
    • COI: 1:CAS:528:DC%2BC38XhtFGhsLzF, PID: 22351110
    • Shen JX, Yakel JL (2012) Functional alpha7 nicotinic ACh receptors on astrocytes in rat hippocampal CA1 slices. J Mol Neurosci 48:14–21. doi:10.1007/s12031-012-9719-3
    • (2012) J Mol Neurosci , vol.48 , pp. 14-21
    • Shen, J.X.1    Yakel, J.L.2
  • 6
    • 84879209063 scopus 로고    scopus 로고
    • Regulated extracellular choline acetyltransferase activity—the plausible missing link of the distant action of acetylcholine in the cholinergic anti-inflammatory pathway
    • COI: 1:CAS:528:DC%2BC3sXhtVKltb7O, PID: 23840379
    • Vijayaraghavan S, Karami A, Aeinehband S, Behbahani H, Grandien A, Nilsson B, Ekdahl KN, Lindblom RP, Piehl F, Darreh-Shori T (2013) Regulated extracellular choline acetyltransferase activity—the plausible missing link of the distant action of acetylcholine in the cholinergic anti-inflammatory pathway. PLoS One 8:e65936. doi:10.1371/journal.pone.0065936
    • (2013) PLoS One , vol.8 , pp. e65936
    • Vijayaraghavan, S.1    Karami, A.2    Aeinehband, S.3    Behbahani, H.4    Grandien, A.5    Nilsson, B.6    Ekdahl, K.N.7    Lindblom, R.P.8    Piehl, F.9    Darreh-Shori, T.10
  • 7
    • 84932195812 scopus 로고    scopus 로고
    • The human CHRNA7 and CHRFAM7A genes: a review of the genetics, regulation, and function
    • COI: 1:CAS:528:DC%2BC2MXjt1arurc%3D, PID: 25701707
    • Sinkus ML, Graw S, Freedman R, Ross RG, Lester HA, Leonard S (2015) The human CHRNA7 and CHRFAM7A genes: a review of the genetics, regulation, and function. Neuropharmacology 96:274–288. doi:10.1016/j.neuropharm.2015.02.006
    • (2015) Neuropharmacology , vol.96 , pp. 274-288
    • Sinkus, M.L.1    Graw, S.2    Freedman, R.3    Ross, R.G.4    Lester, H.A.5    Leonard, S.6
  • 9
    • 18144395496 scopus 로고    scopus 로고
    • Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures
    • COI: 1:CAS:528:DC%2BD2MXjs1elsbg%3D
    • De Simone R, Ajmone-Cat MA, Carnevale D, Minghetti L (2005) Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures. J Neuroinflamm 2:4. doi:10.1186/1742-2094-2-4
    • (2005) J Neuroinflamm , vol.2 , pp. 4
    • De Simone, R.1    Ajmone-Cat, M.A.2    Carnevale, D.3    Minghetti, L.4
  • 10
    • 33744920090 scopus 로고    scopus 로고
    • Microglial alpha7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role
    • COI: 1:CAS:528:DC%2BD28XmtlOqt74%3D, PID: 16652343
    • Suzuki T, Hide I, Matsubara A, Hama C, Harada K, Miyano K, Andra M, Matsubayashi H, Sakai N, Kohsaka S, Inoue K, Nakata Y (2006) Microglial alpha7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role. J Neurosci Res 83:1461–1470. doi:10.1002/jnr.20850
    • (2006) J Neurosci Res , vol.83 , pp. 1461-1470
    • Suzuki, T.1    Hide, I.2    Matsubara, A.3    Hama, C.4    Harada, K.5    Miyano, K.6    Andra, M.7    Matsubayashi, H.8    Sakai, N.9    Kohsaka, S.10    Inoue, K.11    Nakata, Y.12
  • 11
    • 34447115746 scopus 로고    scopus 로고
    • Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action
    • PID: 17581257
    • Park HJ, Lee PH, Ahn YW, Choi YJ, Lee G, Lee DY, Chung ES, Jin BK (2007) Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action. Eur J Neurosci 26:79–89. doi:10.1111/j.1460-9568.2007.05636.x
    • (2007) Eur J Neurosci , vol.26 , pp. 79-89
    • Park, H.J.1    Lee, P.H.2    Ahn, Y.W.3    Choi, Y.J.4    Lee, G.5    Lee, D.Y.6    Chung, E.S.7    Jin, B.K.8
  • 13
    • 84882642320 scopus 로고    scopus 로고
    • The microglial alpha7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2
    • COI: 1:CAS:528:DC%2BC3sXhsFWnt7rE, PID: 23311871
    • Parada E, Egea J, Buendia I, Negredo P, Cunha AC, Cardoso S, Soares MP, Lopez MG (2013) The microglial alpha7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2. Antioxid Redox Signal 19:1135–1148. doi:10.1089/ars.2012.4671
    • (2013) Antioxid Redox Signal , vol.19 , pp. 1135-1148
    • Parada, E.1    Egea, J.2    Buendia, I.3    Negredo, P.4    Cunha, A.C.5    Cardoso, S.6    Soares, M.P.7    Lopez, M.G.8
  • 14
    • 67749108060 scopus 로고    scopus 로고
    • Functional alpha 7-containing nicotinic receptors of NG2-expressing cells in the hippocampus
    • PID: 19170184
    • Velez-Fort M, Audinat E, Angulo MC (2009) Functional alpha 7-containing nicotinic receptors of NG2-expressing cells in the hippocampus. Glia 57:1104–1114. doi:10.1002/glia.20834
    • (2009) Glia , vol.57 , pp. 1104-1114
    • Velez-Fort, M.1    Audinat, E.2    Angulo, M.C.3
  • 15
    • 84871543510 scopus 로고    scopus 로고
    • Functional alpha7beta2 nicotinic acetylcholine receptors expressed in hippocampal interneurons exhibit high sensitivity to pathological level of amyloid beta peptides
    • COI: 1:CAS:528:DC%2BC3sXksFGms7s%3D, PID: 23272676
    • Liu Q, Huang Y, Shen J, Steffensen S, Wu J (2012) Functional alpha7beta2 nicotinic acetylcholine receptors expressed in hippocampal interneurons exhibit high sensitivity to pathological level of amyloid beta peptides. BMC Neurosci 13:155. doi:10.1186/1471-2202-13-155
    • (2012) BMC Neurosci , vol.13 , pp. 155
    • Liu, Q.1    Huang, Y.2    Shen, J.3    Steffensen, S.4    Wu, J.5
  • 16
    • 84906314852 scopus 로고    scopus 로고
    • The novel alpha7beta2-nicotinic acetylcholine receptor subtype is expressed in mouse and human basal forebrain: biochemical and pharmacological characterization
    • PID: 25002271, COI: 1:CAS:528:DC%2BC2cXhs1eksb3E
    • Moretti M, Zoli M, George AA, Lukas RJ, Pistillo F, Maskos U, Whiteaker P, Gotti C (2014) The novel alpha7beta2-nicotinic acetylcholine receptor subtype is expressed in mouse and human basal forebrain: biochemical and pharmacological characterization. Mol Pharmacol 86:306–317. doi:10.1124/mol.114.093377
    • (2014) Mol Pharmacol , vol.86 , pp. 306-317
    • Moretti, M.1    Zoli, M.2    George, A.A.3    Lukas, R.J.4    Pistillo, F.5    Maskos, U.6    Whiteaker, P.7    Gotti, C.8
  • 17
    • 0037941621 scopus 로고    scopus 로고
    • Nicotinic receptors on local circuit neurons in dentate gyrus: a potential role in regulation of granule cell excitability
    • COI: 1:CAS:528:DC%2BD3sXlsFajur8%3D, PID: 12611982
    • Frazier CJ, Strowbridge BW, Papke RL (2003) Nicotinic receptors on local circuit neurons in dentate gyrus: a potential role in regulation of granule cell excitability. J Neurophysiol 89:3018–3028. doi:10.1152/jn.01036.2002
    • (2003) J Neurophysiol , vol.89 , pp. 3018-3028
    • Frazier, C.J.1    Strowbridge, B.W.2    Papke, R.L.3
  • 18
    • 84868133905 scopus 로고    scopus 로고
    • Nicotinic ACh receptors in the hippocampus: role in excitability and plasticity
    • COI: 1:CAS:528:DC%2BC38Xhs1SrurzF, PID: 22472168
    • Yakel JL (2012) Nicotinic ACh receptors in the hippocampus: role in excitability and plasticity. Nicotine Tob Res 14:1249–1257. doi:10.1093/ntr/nts091
    • (2012) Nicotine Tob Res , vol.14 , pp. 1249-1257
    • Yakel, J.L.1
  • 19
    • 33748745959 scopus 로고    scopus 로고
    • Stimulation of alpha7 nicotinic acetylcholine receptor inhibits CD14 and the toll-like receptor 4 expression in human monocytes
    • COI: 1:CAS:528:DC%2BD28XhtFWlu7%2FI, PID: 16980882
    • Hamano R, Takahashi HK, Iwagaki H, Yoshino T, Nishibori M, Tanaka N (2006) Stimulation of alpha7 nicotinic acetylcholine receptor inhibits CD14 and the toll-like receptor 4 expression in human monocytes. Shock. 26:358–364. doi:10.1097/01.shk.0000228168.86845.60
    • (2006) Shock. , vol.26 , pp. 358-364
    • Hamano, R.1    Takahashi, H.K.2    Iwagaki, H.3    Yoshino, T.4    Nishibori, M.5    Tanaka, N.6
  • 20
    • 33748713337 scopus 로고    scopus 로고
    • Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of I-kappaB phosphorylation and nuclear factor-kappaB transcriptional activity through nicotinic acetylcholine receptor alpha7
    • COI: 1:CAS:528:DC%2BD28XhtF2qsbnO, PID: 16968406
    • Yoshikawa H, Kurokawa M, Ozaki N, Nara K, Atou K, Takada E, Kamochi H, Suzuki N (2006) Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of I-kappaB phosphorylation and nuclear factor-kappaB transcriptional activity through nicotinic acetylcholine receptor alpha7. Clin Exp Immunol 146:116–123. doi:10.1111/j.1365-2249.2006.03169.x
    • (2006) Clin Exp Immunol , vol.146 , pp. 116-123
    • Yoshikawa, H.1    Kurokawa, M.2    Ozaki, N.3    Nara, K.4    Atou, K.5    Takada, E.6    Kamochi, H.7    Suzuki, N.8
  • 21
    • 67650391166 scopus 로고    scopus 로고
    • The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE
    • COI: 1:CAS:528:DC%2BD1MXotlajtL8%3D, PID: 19593403
    • Rosas-Ballina M, Goldstein RS, Gallowitsch-Puerta M, Yang L, Valdes-Ferrer SI, Patel NB, Chavan S, Al-Abed Y, Yang H, Tracey KJ (2009) The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE. Mol Med 15:195–202. doi:10.2119/molmed.2009.00039
    • (2009) Mol Med , vol.15 , pp. 195-202
    • Rosas-Ballina, M.1    Goldstein, R.S.2    Gallowitsch-Puerta, M.3    Yang, L.4    Valdes-Ferrer, S.I.5    Patel, N.B.6    Chavan, S.7    Al-Abed, Y.8    Yang, H.9    Tracey, K.J.10
  • 22
    • 0033120111 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase, stress-activated protein kinase/c-Jun N-terminal kinase, and p38mapk are involved in IL-10-mediated selective repression of TNF-alpha-induced activation and maturation of human peripheral blood monocyte-derived dendritic cells
    • COI: 1:CAS:528:DyaK1MXitFGqtrc%3D, PID: 10201904
    • Sato K, Nagayama H, Tadokoro K, Juji T, Takahashi TA (1999) Extracellular signal-regulated kinase, stress-activated protein kinase/c-Jun N-terminal kinase, and p38mapk are involved in IL-10-mediated selective repression of TNF-alpha-induced activation and maturation of human peripheral blood monocyte-derived dendritic cells. J Immunol 162:3865–3872
    • (1999) J Immunol , vol.162 , pp. 3865-3872
    • Sato, K.1    Nagayama, H.2    Tadokoro, K.3    Juji, T.4    Takahashi, T.A.5
  • 26
    • 78650939541 scopus 로고    scopus 로고
    • Function of partially duplicated human alpha7 nicotinic receptor subunit CHRFAM7A gene: potential implications for the cholinergic anti-inflammatory response
    • PID: 21047781, COI: 1:CAS:528:DC%2BC3MXmvVeg
    • de Lucas-Cerrillo AM, Maldifassi MC, Arnalich F, Renart J, Atienza G, Serantes R, Cruces J, Sanchez-Pacheco A, Andres-Mateos E, Montiel C (2011) Function of partially duplicated human alpha7 nicotinic receptor subunit CHRFAM7A gene: potential implications for the cholinergic anti-inflammatory response. J Biol Chem 286:594–606. doi:10.1074/jbc.M110.180067
    • (2011) J Biol Chem , vol.286 , pp. 594-606
    • de Lucas-Cerrillo, A.M.1    Maldifassi, M.C.2    Arnalich, F.3    Renart, J.4    Atienza, G.5    Serantes, R.6    Cruces, J.7    Sanchez-Pacheco, A.8    Andres-Mateos, E.9    Montiel, C.10
  • 28
    • 69349105057 scopus 로고    scopus 로고
    • Alpha 7 nicotinic acetylcholine receptor modulates lymphocyte activation
    • COI: 1:CAS:528:DC%2BD1MXhtV2ktbrJ, PID: 19632243
    • De Rosa MJ, Dionisio L, Agriello E, Bouzat C, Esandi Mdel C (2009) Alpha 7 nicotinic acetylcholine receptor modulates lymphocyte activation. Life Sci. 85:444–449. doi:10.1016/j.lfs.2009.07.010
    • (2009) Life Sci. , vol.85 , pp. 444-449
    • De Rosa, M.J.1    Dionisio, L.2    Agriello, E.3    Bouzat, C.4    Esandi Mdel, C.5
  • 29
    • 0141569322 scopus 로고    scopus 로고
    • Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines
    • COI: 1:CAS:528:DC%2BD3sXnslGrurY%3D, PID: 14500745
    • Skok MV, Kalashnik EN, Koval LN, Tsetlin VI, Utkin YN, Changeux JP, Grailhe R (2003) Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines. Mol Pharmacol 64:885–889. doi:10.1124/mol.64.4.885
    • (2003) Mol Pharmacol , vol.64 , pp. 885-889
    • Skok, M.V.1    Kalashnik, E.N.2    Koval, L.N.3    Tsetlin, V.I.4    Utkin, Y.N.5    Changeux, J.P.6    Grailhe, R.7
  • 30
    • 34249283363 scopus 로고    scopus 로고
    • Expression and function of genes encoding cholinergic components in murine immune cells
    • COI: 1:CAS:528:DC%2BD2sXmtVehtL8%3D, PID: 17383684
    • Kawashima K, Yoshikawa K, Fujii YX, Moriwaki Y, Misawa H (2007) Expression and function of genes encoding cholinergic components in murine immune cells. Life Sci 80:2314–2319. doi:10.1016/j.lfs.2007.02.036
    • (2007) Life Sci , vol.80 , pp. 2314-2319
    • Kawashima, K.1    Yoshikawa, K.2    Fujii, Y.X.3    Moriwaki, Y.4    Misawa, H.5
  • 31
    • 17144370981 scopus 로고    scopus 로고
    • Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation
    • COI: 1:CAS:528:DC%2BD2MXjtFWls70%3D, PID: 15809354
    • Saeed RW, Varma S, Peng-Nemeroff T, Sherry B, Balakhaneh D, Huston J, Tracey KJ, Al-Abed Y, Metz CN (2005) Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. J Exp Med 201:1113–1123. doi:10.1084/jem.20040463
    • (2005) J Exp Med , vol.201 , pp. 1113-1123
    • Saeed, R.W.1    Varma, S.2    Peng-Nemeroff, T.3    Sherry, B.4    Balakhaneh, D.5    Huston, J.6    Tracey, K.J.7    Al-Abed, Y.8    Metz, C.N.9
  • 32
    • 0034126719 scopus 로고    scopus 로고
    • Receptor-mediated inhibition of keratinocyte migration by nicotine involves modulations of calcium influx and intracellular concentration
    • COI: 1:CAS:528:DC%2BD3cXjsleksbc%3D, PID: 10869400
    • Zia S, Ndoye A, Lee TX, Webber RJ, Grando SA (2000) Receptor-mediated inhibition of keratinocyte migration by nicotine involves modulations of calcium influx and intracellular concentration. J Pharmacol Exp Ther 293:973–981
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 973-981
    • Zia, S.1    Ndoye, A.2    Lee, T.X.3    Webber, R.J.4    Grando, S.A.5
  • 33
    • 0344443178 scopus 로고    scopus 로고
    • Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda
    • COI: 1:CAS:528:DC%2BD3sXovVWqtb4%3D, PID: 14506129
    • Chimienti F, Hogg RC, Plantard L, Lehmann C, Brakch N, Fischer J, Huber M, Bertrand D, Hohl D (2003) Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda. Hum Mol Genet 12:3017–3024. doi:10.1093/hmg/ddg320
    • (2003) Hum Mol Genet , vol.12 , pp. 3017-3024
    • Chimienti, F.1    Hogg, R.C.2    Plantard, L.3    Lehmann, C.4    Brakch, N.5    Fischer, J.6    Huber, M.7    Bertrand, D.8    Hohl, D.9
  • 34
    • 36849073794 scopus 로고    scopus 로고
    • Nicotine inhibits cytokine production by placenta cells via NFkappaB: potential role in pregnancy-induced hypertension
    • COI: 1:CAS:528:DC%2BD1cXitVyguw%3D%3D, PID: 17878927
    • Dowling O, Rochelson B, Way K, Al-Abed Y, Metz CN (2007) Nicotine inhibits cytokine production by placenta cells via NFkappaB: potential role in pregnancy-induced hypertension. Mol Med 13:576–583. doi:10.2119/2007-00067.Dowling
    • (2007) Mol Med , vol.13 , pp. 576-583
    • Dowling, O.1    Rochelson, B.2    Way, K.3    Al-Abed, Y.4    Metz, C.N.5
  • 35
    • 67649207033 scopus 로고    scopus 로고
    • Nicotine activates and up-regulates nicotinic acetylcholine receptors in bronchial epithelial cells
    • COI: 1:CAS:528:DC%2BD1MXnvF2mu78%3D, PID: 19097990
    • Fu XW, Lindstrom J, Spindel ER (2009) Nicotine activates and up-regulates nicotinic acetylcholine receptors in bronchial epithelial cells. Am J Respir Cell Mol Biol 41:93–99. doi:10.1165/rcmb.2008-0352OC
    • (2009) Am J Respir Cell Mol Biol , vol.41 , pp. 93-99
    • Fu, X.W.1    Lindstrom, J.2    Spindel, E.R.3
  • 36
    • 79953737886 scopus 로고    scopus 로고
    • Human platelets express functional alpha7-nicotinic acetylcholine receptors
    • COI: 1:CAS:528:DC%2BC3MXjt1Gms70%3D, PID: 21051662
    • Schedel A, Thornton S, Schloss P, Kluter H, Bugert P (2011) Human platelets express functional alpha7-nicotinic acetylcholine receptors. Arterioscler Thromb Vasc Biol 31:928–934. doi:10.1161/ATVBAHA.110.218297
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 928-934
    • Schedel, A.1    Thornton, S.2    Schloss, P.3    Kluter, H.4    Bugert, P.5
  • 37
    • 84870998884 scopus 로고    scopus 로고
    • The nicotinic acetylcholine receptor alpha7 in subcutaneous mature adipocytes: downregulation in human obesity and modulation by diet-induced weight loss
    • COI: 1:CAS:528:DC%2BC38XhvVelu77O
    • Cancello R, Zulian A, Maestrini S, Mencarelli M, Della Barba A, Invitti C, Liuzzi A, Di Blasio AM (2012) The nicotinic acetylcholine receptor alpha7 in subcutaneous mature adipocytes: downregulation in human obesity and modulation by diet-induced weight loss. Int J Obes (Lond) 36:1552–1557. doi:10.1038/ijo.2011.275
    • (2012) Int J Obes (Lond) , vol.36 , pp. 1552-1557
    • Cancello, R.1    Zulian, A.2    Maestrini, S.3    Mencarelli, M.4    Della Barba, A.5    Invitti, C.6    Liuzzi, A.7    Di Blasio, A.M.8
  • 38
    • 55849118078 scopus 로고    scopus 로고
    • Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor
    • COI: 1:CAS:528:DC%2BD1cXhsV2hs7bN, PID: 18975306
    • Waldburger JM, Boyle DL, Pavlov VA, Tracey KJ, Firestein GS (2008) Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor. Arthritis Rheum 58:3439–3449. doi:10.1002/art.23987
    • (2008) Arthritis Rheum , vol.58 , pp. 3439-3449
    • Waldburger, J.M.1    Boyle, D.L.2    Pavlov, V.A.3    Tracey, K.J.4    Firestein, G.S.5
  • 39
    • 79956222665 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor alpha7 subunit is time-dependently expressed in distinct cell types during skin wound healing in mice
    • COI: 1:CAS:528:DC%2BC3MXjvVSksr4%3D, PID: 21437621
    • Fan YY, Yu TS, Wang T, Liu WW, Zhao R, Zhang ST, Ma WX, Zheng JL, Guan DW (2011) Nicotinic acetylcholine receptor alpha7 subunit is time-dependently expressed in distinct cell types during skin wound healing in mice. Histochem Cell Biol 135:375–387. doi:10.1007/s00418-011-0798-y
    • (2011) Histochem Cell Biol , vol.135 , pp. 375-387
    • Fan, Y.Y.1    Yu, T.S.2    Wang, T.3    Liu, W.W.4    Zhao, R.5    Zhang, S.T.6    Ma, W.X.7    Zheng, J.L.8    Guan, D.W.9
  • 40
    • 33645092410 scopus 로고    scopus 로고
    • Acetylcholine causes an increase of intracellular calcium in human sperm
    • COI: 1:CAS:528:DC%2BD28XhvVektr0%3D, PID: 16421212
    • Bray C, Son JH, Meizel S (2005) Acetylcholine causes an increase of intracellular calcium in human sperm. Mol Hum Reprod 11:881–889. doi:10.1093/molehr/gah245
    • (2005) Mol Hum Reprod , vol.11 , pp. 881-889
    • Bray, C.1    Son, J.H.2    Meizel, S.3
  • 41
    • 0842331314 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor subtypes in the rat sympathetic ganglion: pharmacological characterization, subcellular distribution and effect of pre- and postganglionic nerve crush
    • PID: 14989600
    • Del Signore A, Gotti C, Rizzo A, Moretti M, Paggi P (2004) Nicotinic acetylcholine receptor subtypes in the rat sympathetic ganglion: pharmacological characterization, subcellular distribution and effect of pre- and postganglionic nerve crush. J Neuropathol Exp Neurol 63:138–150
    • (2004) J Neuropathol Exp Neurol , vol.63 , pp. 138-150
    • Del Signore, A.1    Gotti, C.2    Rizzo, A.3    Moretti, M.4    Paggi, P.5
  • 42
    • 84907257186 scopus 로고    scopus 로고
    • Functional expression of alpha7-nicotinic acetylcholine receptors by muscle afferent neurons
    • COI: 1:CAS:528:DC%2BC2cXhvFyitrfO, PID: 24966300
    • Baxter JC, Ramachandra R, Mayne DR, Elmslie KS (2014) Functional expression of alpha7-nicotinic acetylcholine receptors by muscle afferent neurons. J Neurophysiol 112:1549–1558. doi:10.1152/jn.00035.2014
    • (2014) J Neurophysiol , vol.112 , pp. 1549-1558
    • Baxter, J.C.1    Ramachandra, R.2    Mayne, D.R.3    Elmslie, K.S.4
  • 43
    • 0030758521 scopus 로고    scopus 로고
    • Detection of functional nicotinic receptors blocked by alpha-bungarotoxin on PC12 cells and dependence of their expression on post-translational events
    • COI: 1:CAS:528:DyaK2sXlt1Cmsr4%3D, PID: 9236221
    • Blumenthal EM, Conroy WG, Romano SJ, Kassner PD, Berg DK (1997) Detection of functional nicotinic receptors blocked by alpha-bungarotoxin on PC12 cells and dependence of their expression on post-translational events. J Neurosci 17:6094–6104
    • (1997) J Neurosci , vol.17 , pp. 6094-6104
    • Blumenthal, E.M.1    Conroy, W.G.2    Romano, S.J.3    Kassner, P.D.4    Berg, D.K.5
  • 44
    • 0028176058 scopus 로고
    • Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes
    • COI: 1:CAS:528:DyaK2cXkslCgsLc%3D, PID: 8145738
    • Peng X, Katz M, Gerzanich V, Anand R, Lindstrom J (1994) Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes. Mol Pharmacol 45:546–554
    • (1994) Mol Pharmacol , vol.45 , pp. 546-554
    • Peng, X.1    Katz, M.2    Gerzanich, V.3    Anand, R.4    Lindstrom, J.5
  • 45
    • 0030962495 scopus 로고    scopus 로고
    • Host cell-specific folding and assembly of the neuronal nicotinic acetylcholine receptor alpha7 subunit
    • COI: 1:STN:280:DyaK2s3mtlKhtQ%3D%3D, PID: 9109542
    • Cooper ST, Millar NS (1997) Host cell-specific folding and assembly of the neuronal nicotinic acetylcholine receptor alpha7 subunit. J Neurochem 68:2140–2151
    • (1997) J Neurochem , vol.68 , pp. 2140-2151
    • Cooper, S.T.1    Millar, N.S.2
  • 47
    • 84871567505 scopus 로고    scopus 로고
    • Identification and characterization of poly(I:C)-induced molecular responses attenuated by nicotine in mouse macrophages
    • COI: 1:CAS:528:DC%2BC3sXhsFKit74%3D, PID: 23028093
    • Cui WY, Zhao S, Polanowska-Grabowska R, Wang J, Wei J, Dash B, Chang SL, Saucerman JJ, Gu J, Li MD (2013) Identification and characterization of poly(I:C)-induced molecular responses attenuated by nicotine in mouse macrophages. Mol Pharmacol 83:61–72. doi:10.1124/mol.112.081497
    • (2013) Mol Pharmacol , vol.83 , pp. 61-72
    • Cui, W.Y.1    Zhao, S.2    Polanowska-Grabowska, R.3    Wang, J.4    Wei, J.5    Dash, B.6    Chang, S.L.7    Saucerman, J.J.8    Gu, J.9    Li, M.D.10
  • 48
  • 49
    • 0032501163 scopus 로고    scopus 로고
    • Nicotine inhibits the production of inflammatory mediators in U937 cells through modulation of nuclear factor-kappaB activation
    • COI: 1:CAS:528:DyaK1cXnsVKntbo%3D, PID: 9813140
    • Sugano N, Shimada K, Ito K, Murai S (1998) Nicotine inhibits the production of inflammatory mediators in U937 cells through modulation of nuclear factor-kappaB activation. Biochem Biophys Res Commun 252:25–28
    • (1998) Biochem Biophys Res Commun , vol.252 , pp. 25-28
    • Sugano, N.1    Shimada, K.2    Ito, K.3    Murai, S.4
  • 50
    • 0033577455 scopus 로고    scopus 로고
    • Inducible, heterologous expression of human alpha7-nicotinic acetylcholine receptors in a native nicotinic receptor-null human clonal line
    • COI: 1:CAS:528:DyaK1MXisV2gsr4%3D, PID: 10216184
    • Peng JH, Lucero L, Fryer J, Herl J, Leonard SS, Lukas RJ (1999) Inducible, heterologous expression of human alpha7-nicotinic acetylcholine receptors in a native nicotinic receptor-null human clonal line. Brain Res 825:172–179
    • (1999) Brain Res , vol.825 , pp. 172-179
    • Peng, J.H.1    Lucero, L.2    Fryer, J.3    Herl, J.4    Leonard, S.S.5    Lukas, R.J.6
  • 51
    • 27344437870 scopus 로고    scopus 로고
    • Alpha7 neuronal nicotinic acetylcholine receptors are negatively regulated by tyrosine phosphorylation and Src-family kinases
    • COI: 1:CAS:528:DC%2BD2MXht1Shsb7K, PID: 16251431
    • Charpantier E, Wiesner A, Huh KH, Ogier R, Hoda JC, Allaman G, Raggenbass M, Feuerbach D, Bertrand D, Fuhrer C (2005) Alpha7 neuronal nicotinic acetylcholine receptors are negatively regulated by tyrosine phosphorylation and Src-family kinases. J Neurosci 25:9836–9849. doi:10.1523/JNEUROSCI.3497-05.2005
    • (2005) J Neurosci , vol.25 , pp. 9836-9849
    • Charpantier, E.1    Wiesner, A.2    Huh, K.H.3    Ogier, R.4    Hoda, J.C.5    Allaman, G.6    Raggenbass, M.7    Feuerbach, D.8    Bertrand, D.9    Fuhrer, C.10
  • 52
    • 13444291352 scopus 로고    scopus 로고
    • Coupling of human nicotinic acetylcholine receptors alpha 7 to calcium channels in GH3 cells
    • COI: 1:CAS:528:DC%2BD2MXhtFOksrc%3D, PID: 15695160
    • Feuerbach D, Lingenhohl K, Dobbins P, Mosbacher J, Corbett N, Nozulak J, Hoyer D (2005) Coupling of human nicotinic acetylcholine receptors alpha 7 to calcium channels in GH3 cells. Neuropharmacology 48:215–227. doi:10.1016/j.neuropharm.2004.10.003
    • (2005) Neuropharmacology , vol.48 , pp. 215-227
    • Feuerbach, D.1    Lingenhohl, K.2    Dobbins, P.3    Mosbacher, J.4    Corbett, N.5    Nozulak, J.6    Hoyer, D.7
  • 53
    • 0035999547 scopus 로고    scopus 로고
    • Expression of an alpha7 duplicate nicotinic acetylcholine receptor-related protein in human leukocytes
    • COI: 1:CAS:528:DC%2BD38XjvVaqt7w%3D, PID: 12020960
    • Villiger Y, Szanto I, Jaconi S, Blanchet C, Buisson B, Krause KH, Bertrand D, Romand JA (2002) Expression of an alpha7 duplicate nicotinic acetylcholine receptor-related protein in human leukocytes. J Neuroimmunol 126:86–98
    • (2002) J Neuroimmunol , vol.126 , pp. 86-98
    • Villiger, Y.1    Szanto, I.2    Jaconi, S.3    Blanchet, C.4    Buisson, B.5    Krause, K.H.6    Bertrand, D.7    Romand, J.A.8
  • 54
    • 20744452466 scopus 로고    scopus 로고
    • Why doesn’t nicotinic ACh receptor immunoreactivity knock out?
    • COI: 1:CAS:528:DC%2BD2MXlsVequrk%3D, PID: 15979499
    • Jones IW, Wonnacott S (2005) Why doesn’t nicotinic ACh receptor immunoreactivity knock out? Trends Neurosci 28:343–345. doi:10.1016/j.tins.2005.04.010
    • (2005) Trends Neurosci , vol.28 , pp. 343-345
    • Jones, I.W.1    Wonnacott, S.2
  • 55
    • 0036088192 scopus 로고    scopus 로고
    • Methyllycaconitine is a potent antagonist of alpha-conotoxin-MII-sensitive presynaptic nicotinic acetylcholine receptors in rat striatum
    • COI: 1:CAS:528:DC%2BD38Xlt1Snsro%3D, PID: 12065717
    • Mogg AJ, Whiteaker P, McIntosh JM, Marks M, Collins AC, Wonnacott S (2002) Methyllycaconitine is a potent antagonist of alpha-conotoxin-MII-sensitive presynaptic nicotinic acetylcholine receptors in rat striatum. J Pharmacol Exp Ther 302:197–204
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 197-204
    • Mogg, A.J.1    Whiteaker, P.2    McIntosh, J.M.3    Marks, M.4    Collins, A.C.5    Wonnacott, S.6
  • 56
    • 84893188194 scopus 로고    scopus 로고
    • alpha7 nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways
    • COI: 1:CAS:528:DC%2BC2cXjslKntLc%3D, PID: 24412630
    • Gergalova G, Lykhmus O, Komisarenko S, Skok M (2014) alpha7 nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways. Int J Biochem Cell Biol 49:26–31. doi:10.1016/j.biocel.2014.01.001
    • (2014) Int J Biochem Cell Biol , vol.49 , pp. 26-31
    • Gergalova, G.1    Lykhmus, O.2    Komisarenko, S.3    Skok, M.4
  • 57
    • 84902241261 scopus 로고    scopus 로고
    • Mitochondria express several nicotinic acetylcholine receptor subtypes to control various pathways of apoptosis induction
    • COI: 1:CAS:528:DC%2BC2cXhtF2kur%2FN, PID: 24880090
    • Lykhmus O, Gergalova G, Koval L, Zhmak M, Komisarenko S, Skok M (2014) Mitochondria express several nicotinic acetylcholine receptor subtypes to control various pathways of apoptosis induction. Int J Biochem Cell Biol 53:246–252. doi:10.1016/j.biocel.2014.05.030
    • (2014) Int J Biochem Cell Biol , vol.53 , pp. 246-252
    • Lykhmus, O.1    Gergalova, G.2    Koval, L.3    Zhmak, M.4    Komisarenko, S.5    Skok, M.6
  • 58
    • 0347359010 scopus 로고    scopus 로고
    • 2+ permeability of nicotinic acetylcholine receptors
    • COI: 1:CAS:528:DC%2BD3sXps1ertLw%3D, PID: 14670366
    • 2+ permeability of nicotinic acetylcholine receptors. Cell Calcium 35:1–8
    • (2004) Cell Calcium , vol.35 , pp. 1-8
    • Fucile, S.1
  • 59
    • 0035957403 scopus 로고    scopus 로고
    • Nicotinic cholinergic signaling in hippocampal astrocytes involves calcium-induced calcium release from intracellular stores
    • COI: 1:CAS:528:DC%2BD3MXis1KhtLo%3D, PID: 11259680
    • Sharma G, Vijayaraghavan S (2001) Nicotinic cholinergic signaling in hippocampal astrocytes involves calcium-induced calcium release from intracellular stores. Proc Natl Acad Sci USA 98:4148–4153. doi:10.1073/pnas.071540198
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4148-4153
    • Sharma, G.1    Vijayaraghavan, S.2
  • 60
    • 0242694942 scopus 로고    scopus 로고
    • Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation
    • COI: 1:CAS:528:DC%2BD3sXovFCls7Y%3D, PID: 14602824
    • Stevens TR, Krueger SR, Fitzsimonds RM, Picciotto MR (2003) Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation. J Neurosci 23:10093–10099
    • (2003) J Neurosci , vol.23 , pp. 10093-10099
    • Stevens, T.R.1    Krueger, S.R.2    Fitzsimonds, R.M.3    Picciotto, M.R.4
  • 61
    • 84930946334 scopus 로고    scopus 로고
    • Activation of alpha7 nicotinic acetylcholine receptors increases intracellular cAMP levels via activation of AC1 in hippocampal neurons
    • COI: 1:CAS:528:DC%2BC2MXnvFeqs7w%3D, PID: 25937212
    • Cheng Q, Yakel JL (2015) Activation of alpha7 nicotinic acetylcholine receptors increases intracellular cAMP levels via activation of AC1 in hippocampal neurons. Neuropharmacology 95:405–414. doi:10.1016/j.neuropharm.2015.04.016
    • (2015) Neuropharmacology , vol.95 , pp. 405-414
    • Cheng, Q.1    Yakel, J.L.2
  • 63
    • 0035957946 scopus 로고    scopus 로고
    • alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity
    • COI: 1:CAS:528:DC%2BD3MXjt12kt74%3D, PID: 11278378
    • Kihara T, Shimohama S, Sawada H, Honda K, Nakamizo T, Shibasaki H, Kume T, Akaike A (2001) alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity. J Biol Chem 276:13541–13546. doi:10.1074/jbc.M008035200
    • (2001) J Biol Chem , vol.276 , pp. 13541-13546
    • Kihara, T.1    Shimohama, S.2    Sawada, H.3    Honda, K.4    Nakamizo, T.5    Shibasaki, H.6    Kume, T.7    Akaike, A.8
  • 64
    • 84943364905 scopus 로고    scopus 로고
    • Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection
    • Egea J, Buendia I, Parada E, Navarro E, Leon R, Lopez MG (2015) Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection. Biochem Pharmacol. doi:10.1016/j.bcp.2015.07.032
    • (2015) Biochem Pharmacol
    • Egea, J.1    Buendia, I.2    Parada, E.3    Navarro, E.4    Leon, R.5    Lopez, M.G.6
  • 65
    • 0346460961 scopus 로고    scopus 로고
    • Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1-42) amyloid
    • COI: 1:CAS:528:DC%2BD38Xosl2mtrg%3D, PID: 12244045
    • Shaw S, Bencherif M, Marrero MB (2002) Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1-42) amyloid. J Biol Chem 277:44920–44924. doi:10.1074/jbc.M204610200
    • (2002) J Biol Chem , vol.277 , pp. 44920-44924
    • Shaw, S.1    Bencherif, M.2    Marrero, M.B.3
  • 67
    • 77956492231 scopus 로고    scopus 로고
    • Unphosphorylated STAT3 modulates alpha 7 nicotinic receptor signaling and cytokine production in sepsis
    • COI: 1:CAS:528:DC%2BC3cXhtV2gurbK, PID: 20706987
    • Pena G, Cai B, Liu J, van der Zanden EP, Deitch EA, de Jonge WJ, Ulloa L (2010) Unphosphorylated STAT3 modulates alpha 7 nicotinic receptor signaling and cytokine production in sepsis. Eur J Immunol 40:2580–2589. doi:10.1002/eji.201040540
    • (2010) Eur J Immunol , vol.40 , pp. 2580-2589
    • Pena, G.1    Cai, B.2    Liu, J.3    van der Zanden, E.P.4    Deitch, E.A.5    de Jonge, W.J.6    Ulloa, L.7
  • 68
    • 84907916535 scopus 로고    scopus 로고
    • A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via alpha7 nicotinic receptors in human macrophages
    • PID: 25259522, COI: 1:CAS:528:DC%2BC2cXhslegtbnO
    • Maldifassi MC, Atienza G, Arnalich F, Lopez-Collazo E, Cedillo JL, Martin-Sanchez C, Bordas A, Renart J, Montiel C (2014) A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via alpha7 nicotinic receptors in human macrophages. PLoS One 9:e108397. doi:10.1371/journal.pone.0108397
    • (2014) PLoS One , vol.9 , pp. e108397
    • Maldifassi, M.C.1    Atienza, G.2    Arnalich, F.3    Lopez-Collazo, E.4    Cedillo, J.L.5    Martin-Sanchez, C.6    Bordas, A.7    Renart, J.8    Montiel, C.9
  • 69
    • 66449111088 scopus 로고    scopus 로고
    • Reflex control of immunity
    • COI: 1:CAS:528:DC%2BD1MXmt1SktLk%3D, PID: 19461672
    • Tracey KJ (2009) Reflex control of immunity. Nat Rev Immunol 9:418–428. doi:10.1038/nri2566
    • (2009) Nat Rev Immunol , vol.9 , pp. 418-428
    • Tracey, K.J.1
  • 70
    • 75449116560 scopus 로고    scopus 로고
    • Inhibitory role of cholinergic system mediated via alpha7 nicotinic acetylcholine receptor in LPS-induced neuro-inflammation
    • COI: 1:CAS:528:DC%2BC3cXns1Sgtbs%3D, PID: 19586999
    • Tyagi E, Agrawal R, Nath C, Shukla R (2010) Inhibitory role of cholinergic system mediated via alpha7 nicotinic acetylcholine receptor in LPS-induced neuro-inflammation. Innate Immun 16:3–13. doi:10.1177/1753425909104680
    • (2010) Innate Immun , vol.16 , pp. 3-13
    • Tyagi, E.1    Agrawal, R.2    Nath, C.3    Shukla, R.4
  • 72
    • 0345171694 scopus 로고    scopus 로고
    • Via beta-adrenoceptors, stimulation of extrasplenic sympathetic nerve fibers inhibits lipopolysaccharide-induced TNF secretion in perfused rat spleen
    • COI: 1:CAS:528:DC%2BD3sXptlOkt70%3D, PID: 14644033
    • Kees MG, Pongratz G, Kees F, Scholmerich J, Straub RH (2003) Via beta-adrenoceptors, stimulation of extrasplenic sympathetic nerve fibers inhibits lipopolysaccharide-induced TNF secretion in perfused rat spleen. J Neuroimmunol 145:77–85
    • (2003) J Neuroimmunol , vol.145 , pp. 77-85
    • Kees, M.G.1    Pongratz, G.2    Kees, F.3    Scholmerich, J.4    Straub, R.H.5
  • 74
    • 79955021499 scopus 로고    scopus 로고
    • alpha7-cholinergic receptor mediates vagal induction of splenic norepinephrine
    • COI: 1:CAS:528:DC%2BC3MXjvVKlsrw%3D, PID: 21339364
    • Vida G, Pena G, Deitch EA, Ulloa L (2011) alpha7-cholinergic receptor mediates vagal induction of splenic norepinephrine. J Immunol 186:4340–4346. doi:10.4049/jimmunol.1003722
    • (2011) J Immunol , vol.186 , pp. 4340-4346
    • Vida, G.1    Pena, G.2    Deitch, E.A.3    Ulloa, L.4
  • 75
    • 84898858078 scopus 로고    scopus 로고
    • The cholinergic anti-inflammatory pathway: a critical review
    • COI: 1:CAS:528:DC%2BC2cXns1Cntg%3D%3D, PID: 24411268
    • Martelli D, McKinley MJ, McAllen RM (2014) The cholinergic anti-inflammatory pathway: a critical review. Auton Neurosci 182:65–69. doi:10.1016/j.autneu.2013.12.007
    • (2014) Auton Neurosci , vol.182 , pp. 65-69
    • Martelli, D.1    McKinley, M.J.2    McAllen, R.M.3
  • 76
    • 2442485876 scopus 로고    scopus 로고
    • Glucocorticoid activation of the neuronal nicotinic acetylcholine receptor alpha7 subunit gene: involvement of transcription factor Egr-1
    • COI: 1:CAS:528:DC%2BD2cXktVOktro%3D, PID: 15147903
    • Carrasco-Serrano C, Criado M (2004) Glucocorticoid activation of the neuronal nicotinic acetylcholine receptor alpha7 subunit gene: involvement of transcription factor Egr-1. FEBS Lett 566:247–250. doi:10.1016/j.febslet.2004.04.049
    • (2004) FEBS Lett , vol.566 , pp. 247-250
    • Carrasco-Serrano, C.1    Criado, M.2
  • 77
    • 84885652983 scopus 로고    scopus 로고
    • Effects of neuronal nicotinic acetylcholine receptor allosteric modulators in animal behavior studies
    • COI: 1:CAS:528:DC%2BC3sXhtVWnsrzE, PID: 23732296
    • Pandya AA, Yakel JL (2013) Effects of neuronal nicotinic acetylcholine receptor allosteric modulators in animal behavior studies. Biochem Pharmacol 86:1054–1062. doi:10.1016/j.bcp.2013.05.018
    • (2013) Biochem Pharmacol , vol.86 , pp. 1054-1062
    • Pandya, A.A.1    Yakel, J.L.2
  • 78
    • 84955466854 scopus 로고    scopus 로고
    • The antinociceptive and antiinflammatory properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of alpha7 nicotinic acetylcholine receptors in mice
    • COI: 1:CAS:528:DC%2BC2MXhslWlt77E, PID: 26280585
    • Bagdas D, Targowska-Duda KM, Lopez JJ, Perez EG, Arias HR, Damaj MI (2015) The antinociceptive and antiinflammatory properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of alpha7 nicotinic acetylcholine receptors in mice. Anesth Analg 121:1369–1377. doi:10.1213/ANE.0000000000000902
    • (2015) Anesth Analg , vol.121 , pp. 1369-1377
    • Bagdas, D.1    Targowska-Duda, K.M.2    Lopez, J.J.3    Perez, E.G.4    Arias, H.R.5    Damaj, M.I.6
  • 79
    • 84881248457 scopus 로고    scopus 로고
    • A positive allosteric modulator of alpha7 nAChRs augments neuroprotective effects of endogenous nicotinic agonists in cerebral ischaemia
    • COI: 1:CAS:528:DC%2BC3sXht1els7%2FP, PID: 23713819
    • Kalappa BI, Sun F, Johnson SR, Jin K, Uteshev VV (2013) A positive allosteric modulator of alpha7 nAChRs augments neuroprotective effects of endogenous nicotinic agonists in cerebral ischaemia. Br J Pharmacol 169:1862–1878. doi:10.1111/bph.12247
    • (2013) Br J Pharmacol , vol.169 , pp. 1862-1878
    • Kalappa, B.I.1    Sun, F.2    Johnson, S.R.3    Jin, K.4    Uteshev, V.V.5
  • 80
    • 84881233510 scopus 로고    scopus 로고
    • A type-II positive allosteric modulator of alpha7 nAChRs reduces brain injury and improves neurological function after focal cerebral ischemia in rats
    • COI: 1:CAS:528:DC%2BC3sXhtlams7jE, PID: 23951360
    • Sun F, Jin K, Uteshev VV (2013) A type-II positive allosteric modulator of alpha7 nAChRs reduces brain injury and improves neurological function after focal cerebral ischemia in rats. PLoS One 8:e73581. doi:10.1371/journal.pone.0073581
    • (2013) PLoS One , vol.8 , pp. e73581
    • Sun, F.1    Jin, K.2    Uteshev, V.V.3
  • 81
    • 84922613651 scopus 로고    scopus 로고
    • High therapeutic potential of positive allosteric modulation of alpha7 nAChRs in a rat model of traumatic brain injury: proof-of-concept
    • COI: 1:CAS:528:DC%2BC2MXitlShsrY%3D, PID: 25647232
    • Gatson JW, Simpkins JW, Uteshev VV (2015) High therapeutic potential of positive allosteric modulation of alpha7 nAChRs in a rat model of traumatic brain injury: proof-of-concept. Brain Res Bull 112:35–41. doi:10.1016/j.brainresbull.2015.01.008
    • (2015) Brain Res Bull , vol.112 , pp. 35-41
    • Gatson, J.W.1    Simpkins, J.W.2    Uteshev, V.V.3
  • 82
    • 41749124775 scopus 로고    scopus 로고
    • Microglia-neuron interaction in inflammatory and degenerative diseases: role of cholinergic and noradrenergic systems
    • COI: 1:CAS:528:DC%2BD1cXitF2kurc%3D
    • Carnevale D, De Simone R, Minghetti L (2007) Microglia-neuron interaction in inflammatory and degenerative diseases: role of cholinergic and noradrenergic systems. CNS Neurol Disord: Drug Targets 6:388–397
    • (2007) CNS Neurol Disord: Drug Targets , vol.6 , pp. 388-397
    • Carnevale, D.1    De Simone, R.2    Minghetti, L.3
  • 83
    • 84907457604 scopus 로고    scopus 로고
    • The experimental autoimmune encephalomyelitis disease course is modulated by nicotine and other cigarette smoke components
    • PID: 25250777, COI: 1:CAS:528:DC%2BC2cXhslSisr7O
    • Gao Z, Nissen JC, Ji K, Tsirka SE (2014) The experimental autoimmune encephalomyelitis disease course is modulated by nicotine and other cigarette smoke components. PLoS One 9:e107979. doi:10.1371/journal.pone.0107979
    • (2014) PLoS One , vol.9 , pp. e107979
    • Gao, Z.1    Nissen, J.C.2    Ji, K.3    Tsirka, S.E.4
  • 84
    • 17044426320 scopus 로고    scopus 로고
    • Rapid upregulation of alpha7 nicotinic acetylcholine receptors by tyrosine dephosphorylation
    • COI: 1:CAS:528:DC%2BD2MXjtlSis7g%3D, PID: 15814802
    • Cho CH, Song W, Leitzell K, Teo E, Meleth AD, Quick MW, Lester RA (2005) Rapid upregulation of alpha7 nicotinic acetylcholine receptors by tyrosine dephosphorylation. J Neurosci 25:3712–3723. doi:10.1523/JNEUROSCI.5389-03.2005
    • (2005) J Neurosci , vol.25 , pp. 3712-3723
    • Cho, C.H.1    Song, W.2    Leitzell, K.3    Teo, E.4    Meleth, A.D.5    Quick, M.W.6    Lester, R.A.7
  • 86
    • 44649174862 scopus 로고    scopus 로고
    • EphB receptors co-distribute with a nicotinic receptor subtype and regulate nicotinic downstream signaling in neurons
    • COI: 1:CAS:528:DC%2BD1cXntlCqtLw%3D, PID: 18403216
    • Liu Z, Conroy WG, Stawicki TM, Nai Q, Neff RA, Berg DK (2008) EphB receptors co-distribute with a nicotinic receptor subtype and regulate nicotinic downstream signaling in neurons. Mol Cell Neurosci 38:236–244. doi:10.1016/j.mcn.2008.02.013
    • (2008) Mol Cell Neurosci , vol.38 , pp. 236-244
    • Liu, Z.1    Conroy, W.G.2    Stawicki, T.M.3    Nai, Q.4    Neff, R.A.5    Berg, D.K.6
  • 87
    • 40349107599 scopus 로고    scopus 로고
    • Molecular characterization and localization of the RIC-3 protein, an effector of nicotinic acetylcholine receptor expression
    • COI: 1:CAS:528:DC%2BD1cXlsl2htbc%3D, PID: 18179477
    • Castelan F, Castillo M, Mulet J, Sala S, Sala F, Dominguez Del Toro E, Criado M (2008) Molecular characterization and localization of the RIC-3 protein, an effector of nicotinic acetylcholine receptor expression. J Neurochem 105:617–627. doi:10.1111/j.1471-4159.2007.05169.x
    • (2008) J Neurochem , vol.105 , pp. 617-627
    • Castelan, F.1    Castillo, M.2    Mulet, J.3    Sala, S.4    Sala, F.5    Dominguez Del Toro, E.6    Criado, M.7
  • 88
    • 40549109577 scopus 로고    scopus 로고
    • Basic and clinical aspects of non-neuronal acetylcholine: biological and clinical significance of non-canonical ligands of epithelial nicotinic acetylcholine receptors
    • COI: 1:CAS:528:DC%2BD1cXivFeit7w%3D, PID: 18285656
    • Grando SA (2008) Basic and clinical aspects of non-neuronal acetylcholine: biological and clinical significance of non-canonical ligands of epithelial nicotinic acetylcholine receptors. J Pharmacol Sci 106:174–179
    • (2008) J Pharmacol Sci , vol.106 , pp. 174-179
    • Grando, S.A.1
  • 89
    • 84874980921 scopus 로고    scopus 로고
    • Identification of single gene deletions at 15q13.3: further evidence that CHRNA7 causes the 15q13.3 microdeletion syndrome phenotype
    • COI: 1:CAS:528:DC%2BC3sXmsFWqsro%3D, PID: 22775350
    • Hoppman-Chaney N, Wain K, Seger PR, Superneau DW, Hodge JC (2013) Identification of single gene deletions at 15q13.3: further evidence that CHRNA7 causes the 15q13.3 microdeletion syndrome phenotype. Clin Genet 83:345–351. doi:10.1111/j.1399-0004.2012.01925.x
    • (2013) Clin Genet , vol.83 , pp. 345-351
    • Hoppman-Chaney, N.1    Wain, K.2    Seger, P.R.3    Superneau, D.W.4    Hodge, J.C.5
  • 90
    • 82755162987 scopus 로고    scopus 로고
    • Transcriptional repression of the alpha7 nicotinic acetylcholine receptor subunit gene (CHRNA7) by activating protein-2alpha (AP-2alpha)
    • COI: 1:CAS:528:DC%2BC3MXhsFKjsr7N, PID: 21979958
    • Finlay-Schultz J, Canastar A, Short M, El Gazzar M, Coughlan C, Leonard S (2011) Transcriptional repression of the alpha7 nicotinic acetylcholine receptor subunit gene (CHRNA7) by activating protein-2alpha (AP-2alpha). J Biol Chem 286:42123–42132. doi:10.1074/jbc.M111.276014
    • (2011) J Biol Chem , vol.286 , pp. 42123-42132
    • Finlay-Schultz, J.1    Canastar, A.2    Short, M.3    El Gazzar, M.4    Coughlan, C.5    Leonard, S.6
  • 91
    • 80054957569 scopus 로고    scopus 로고
    • 15q11.2-13.3 chromatin analysis reveals epigenetic regulation of CHRNA7 with deficiencies in Rett and autism brain
    • COI: 1:CAS:528:DC%2BC3MXhtlGltL3K, PID: 21840925
    • Yasui DH, Scoles HA, Horike S, Meguro-Horike M, Dunaway KW, Schroeder DI, Lasalle JM (2011) 15q11.2-13.3 chromatin analysis reveals epigenetic regulation of CHRNA7 with deficiencies in Rett and autism brain. Hum Mol Genet 20:4311–4323. doi:10.1093/hmg/ddr357
    • (2011) Hum Mol Genet , vol.20 , pp. 4311-4323
    • Yasui, D.H.1    Scoles, H.A.2    Horike, S.3    Meguro-Horike, M.4    Dunaway, K.W.5    Schroeder, D.I.6    Lasalle, J.M.7
  • 92
    • 34547558959 scopus 로고    scopus 로고
    • The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation
    • PID: 17502850, COI: 1:CAS:528:DC%2BD2sXot1yls70%3D
    • de Jonge WJ, Ulloa L (2007) The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation. Br J Pharmacol 151:915–929. doi:10.1038/sj.bjp.0707264
    • (2007) Br J Pharmacol , vol.151 , pp. 915-929
    • de Jonge, W.J.1    Ulloa, L.2
  • 93
    • 84938953920 scopus 로고    scopus 로고
    • cAMP-dependent protein kinase inhibits alpha7 nicotinic receptor activity in layer 1 cortical interneurons through activation of D1/D5 dopamine receptors
    • PID: 25990637
    • Komal P, Estakhr J, Kamran M, Renda A, Nashmi R (2015) cAMP-dependent protein kinase inhibits alpha7 nicotinic receptor activity in layer 1 cortical interneurons through activation of D1/D5 dopamine receptors. J Physiol. doi:10.1113/JP270469
    • (2015) J Physiol
    • Komal, P.1    Estakhr, J.2    Kamran, M.3    Renda, A.4    Nashmi, R.5
  • 94
    • 0035478066 scopus 로고    scopus 로고
    • The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications
    • COI: 1:CAS:528:DC%2BD3MXnsFCksrc%3D, PID: 11567036
    • Hilmas C, Pereira EF, Alkondon M, Rassoulpour A, Schwarcz R, Albuquerque EX (2001) The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications. J Neurosci 21:7463–7473
    • (2001) J Neurosci , vol.21 , pp. 7463-7473
    • Hilmas, C.1    Pereira, E.F.2    Alkondon, M.3    Rassoulpour, A.4    Schwarcz, R.5    Albuquerque, E.X.6
  • 95
    • 84864691584 scopus 로고    scopus 로고
    • Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons
    • COI: 1:CAS:528:DC%2BC38XhtFamsrzE, PID: 22848433
    • Dobelis P, Staley KJ, Cooper DC (2012) Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons. PLoS One 7:e41108. doi:10.1371/journal.pone.0041108
    • (2012) PLoS One , vol.7 , pp. e41108
    • Dobelis, P.1    Staley, K.J.2    Cooper, D.C.3
  • 96
    • 84907190328 scopus 로고    scopus 로고
    • The duplicated alpha7 subunits assemble and form functional nicotinic receptors with the full-length alpha7
    • COI: 1:CAS:528:DC%2BC2cXhsFOqtrbI, PID: 25056953
    • Wang Y, Xiao C, Indersmitten T, Freedman R, Leonard S, Lester HA (2014) The duplicated alpha7 subunits assemble and form functional nicotinic receptors with the full-length alpha7. J Biol Chem 289:26451–26463. doi:10.1074/jbc.M114.582858
    • (2014) J Biol Chem , vol.289 , pp. 26451-26463
    • Wang, Y.1    Xiao, C.2    Indersmitten, T.3    Freedman, R.4    Leonard, S.5    Lester, H.A.6
  • 97
    • 84929158676 scopus 로고    scopus 로고
    • CHRFAM7A, a human-specific and partially duplicated alpha7-nicotinic acetylcholine receptor gene with the potential to specify a human-specific inflammatory response to injury
    • COI: 1:CAS:528:DC%2BC2MXit1Olu70%3D, PID: 25473097
    • Costantini TW, Dang X, Coimbra R, Eliceiri BP, Baird A (2015) CHRFAM7A, a human-specific and partially duplicated alpha7-nicotinic acetylcholine receptor gene with the potential to specify a human-specific inflammatory response to injury. J Leukoc Biol 97:247–257. doi:10.1189/jlb.4RU0814-381R
    • (2015) J Leukoc Biol , vol.97 , pp. 247-257
    • Costantini, T.W.1    Dang, X.2    Coimbra, R.3    Eliceiri, B.P.4    Baird, A.5
  • 98
    • 78650997226 scopus 로고    scopus 로고
    • Expression of the alpha7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS
    • COI: 1:CAS:528:DC%2BC3MXntVahuw%3D%3D, PID: 20926142
    • Benfante R, Antonini RA, De Pizzol M, Gotti C, Clementi F, Locati M, Fornasari D (2011) Expression of the alpha7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS. J Neuroimmunol 230:74–84. doi:10.1016/j.jneuroim.2010.09.008
    • (2011) J Neuroimmunol , vol.230 , pp. 74-84
    • Benfante, R.1    Antonini, R.A.2    De Pizzol, M.3    Gotti, C.4    Clementi, F.5    Locati, M.6    Fornasari, D.7
  • 99
    • 79955713813 scopus 로고    scopus 로고
    • Cholinergic systems mediate action from movement to higher consciousness
    • COI: 1:CAS:528:DC%2BC3MXmtFClu7w%3D, PID: 20060422
    • Woolf NJ, Butcher LL (2011) Cholinergic systems mediate action from movement to higher consciousness. Behav Brain Res 221:488–498. doi:10.1016/j.bbr.2009.12.046
    • (2011) Behav Brain Res , vol.221 , pp. 488-498
    • Woolf, N.J.1    Butcher, L.L.2
  • 100
    • 84922245178 scopus 로고    scopus 로고
    • Dementia praecox redux: a systematic review of the nicotinic receptor as a target for cognitive symptoms of schizophrenia
    • PID: 25567553, COI: 1:CAS:528:DC%2BC2MXislWqsL8%3D
    • Rowe AR, Mercer L, Casetti V, Sendt KV, Giaroli G, Shergill SS, Tracy DK (2015) Dementia praecox redux: a systematic review of the nicotinic receptor as a target for cognitive symptoms of schizophrenia. J Psychopharmacol 29:197–211. doi:10.1177/0269881114564096
    • (2015) J Psychopharmacol , vol.29 , pp. 197-211
    • Rowe, A.R.1    Mercer, L.2    Casetti, V.3    Sendt, K.V.4    Giaroli, G.5    Shergill, S.S.6    Tracy, D.K.7
  • 101
    • 0032440954 scopus 로고    scopus 로고
    • Activation and inhibition of the human alpha7 nicotinic acetylcholine receptor by agonists
    • COI: 1:CAS:528:DyaK1cXnt1Gksrc%3D, PID: 9833639
    • Briggs CA, McKenna DG (1998) Activation and inhibition of the human alpha7 nicotinic acetylcholine receptor by agonists. Neuropharmacology 37:1095–1102
    • (1998) Neuropharmacology , vol.37 , pp. 1095-1102
    • Briggs, C.A.1    McKenna, D.G.2
  • 102
    • 49449094458 scopus 로고    scopus 로고
    • Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans
    • COI: 1:CAS:528:DC%2BD1cXps1Grurg%3D, PID: 18500366
    • Wessler I, Kirkpatrick CJ (2008) Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans. Br J Pharmacol 154:1558–1571. doi:10.1038/bjp.2008.185
    • (2008) Br J Pharmacol , vol.154 , pp. 1558-1571
    • Wessler, I.1    Kirkpatrick, C.J.2
  • 103
    • 0036891571 scopus 로고    scopus 로고
    • Desensitization of neuronal nicotinic receptors
    • COI: 1:CAS:528:DC%2BD38Xps1KlsLk%3D, PID: 12436413
    • Quick MW, Lester RA (2002) Desensitization of neuronal nicotinic receptors. J Neurobiol 53:457–478. doi:10.1002/neu.10109
    • (2002) J Neurobiol , vol.53 , pp. 457-478
    • Quick, M.W.1    Lester, R.A.2
  • 104
    • 65649102955 scopus 로고    scopus 로고
    • Activation and desensitization of nicotinic alpha7-type acetylcholine receptors by benzylidene anabaseines and nicotine
    • COI: 1:CAS:528:DC%2BD1MXlt1OlsLg%3D, PID: 19223664
    • Papke RL, Kem WR, Soti F, Lopez-Hernandez GY, Horenstein NA (2009) Activation and desensitization of nicotinic alpha7-type acetylcholine receptors by benzylidene anabaseines and nicotine. J Pharmacol Exp Ther 329:791–807. doi:10.1124/jpet.108.150151
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 791-807
    • Papke, R.L.1    Kem, W.R.2    Soti, F.3    Lopez-Hernandez, G.Y.4    Horenstein, N.A.5
  • 105
    • 0032520135 scopus 로고    scopus 로고
    • Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells
    • COI: 1:CAS:528:DyaK1cXptlOkug%3D%3D, PID: 9454829
    • Frazier CJ, Rollins YD, Breese CR, Leonard S, Freedman R, Dunwiddie TV (1998) Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells. J Neurosci 18:1187–1195
    • (1998) J Neurosci , vol.18 , pp. 1187-1195
    • Frazier, C.J.1    Rollins, Y.D.2    Breese, C.R.3    Leonard, S.4    Freedman, R.5    Dunwiddie, T.V.6
  • 107
    • 0031410384 scopus 로고    scopus 로고
    • Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons
    • COI: 1:STN:280:DyaK1c7ns1Kmtw%3D%3D, PID: 9517478
    • Alkondon M, Pereira EF, Cortes WS, Maelicke A, Albuquerque EX (1997) Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. Eur J Neurosci 9:2734–2742
    • (1997) Eur J Neurosci , vol.9 , pp. 2734-2742
    • Alkondon, M.1    Pereira, E.F.2    Cortes, W.S.3    Maelicke, A.4    Albuquerque, E.X.5
  • 108
    • 84905587319 scopus 로고    scopus 로고
    • Alpha7 neuronal nicotinic receptor: a pluripotent target for diseases of the central nervous system
    • COI: 1:CAS:528:DC%2BC2cXht1Gnu7vP, PID: 25012615
    • Bencherif M, Narla ST, Stachowiak MS (2014) Alpha7 neuronal nicotinic receptor: a pluripotent target for diseases of the central nervous system. CNS Neurol Disord Drug Targets 13:836–845
    • (2014) CNS Neurol Disord Drug Targets , vol.13 , pp. 836-845
    • Bencherif, M.1    Narla, S.T.2    Stachowiak, M.S.3
  • 109
    • 42049086308 scopus 로고    scopus 로고
    • Elevated inflammation levels in depressed adults with a history of childhood maltreatment
    • PID: 18391129
    • Danese A, Moffitt TE, Pariante CM, Ambler A, Poulton R, Caspi A (2008) Elevated inflammation levels in depressed adults with a history of childhood maltreatment. Arch Gen Psychiatry 65:409–415. doi:10.1001/archpsyc.65.4.409
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 409-415
    • Danese, A.1    Moffitt, T.E.2    Pariante, C.M.3    Ambler, A.4    Poulton, R.5    Caspi, A.6
  • 110
    • 0042655450 scopus 로고    scopus 로고
    • Life event dimensions of loss, humiliation, entrapment, and danger in the prediction of onsets of major depression and generalized anxiety
    • PID: 12912762
    • Kendler KS, Hettema JM, Butera F, Gardner CO, Prescott CA (2003) Life event dimensions of loss, humiliation, entrapment, and danger in the prediction of onsets of major depression and generalized anxiety. Arch Gen Psychiatry 60:789–796. doi:10.1001/archpsyc.60.8.789
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 789-796
    • Kendler, K.S.1    Hettema, J.M.2    Butera, F.3    Gardner, C.O.4    Prescott, C.A.5
  • 111
    • 84860012576 scopus 로고    scopus 로고
    • Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk
    • COI: 1:CAS:528:DC%2BC38Xmt12mt70%3D, PID: 22474371
    • Cohen S, Janicki-Deverts D, Doyle WJ, Miller GE, Frank E, Rabin BS, Turner RB (2012) Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. Proc Natl Acad Sci USA 109:5995–5999. doi:10.1073/pnas.1118355109
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 5995-5999
    • Cohen, S.1    Janicki-Deverts, D.2    Doyle, W.J.3    Miller, G.E.4    Frank, E.5    Rabin, B.S.6    Turner, R.B.7
  • 112
    • 84901660044 scopus 로고    scopus 로고
    • Childhood bullying involvement predicts low-grade systemic inflammation into adulthood
    • COI: 1:CAS:528:DC%2BC2cXnsl2ms7w%3D, PID: 24821813
    • Copeland WE, Wolke D, Lereya ST, Shanahan L, Worthman C, Costello EJ (2014) Childhood bullying involvement predicts low-grade systemic inflammation into adulthood. Proc Natl Acad Sci USA 111:7570–7575. doi:10.1073/pnas.1323641111
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 7570-7575
    • Copeland, W.E.1    Wolke, D.2    Lereya, S.T.3    Shanahan, L.4    Worthman, C.5    Costello, E.J.6
  • 113
    • 84884145584 scopus 로고    scopus 로고
    • The emerging field of human social genomics
    • PID: 23853742
    • Slavich GM, Cole SW (2013) The emerging field of human social genomics. Clin Psychol Sci 1:331–348
    • (2013) Clin Psychol Sci , vol.1 , pp. 331-348
    • Slavich, G.M.1    Cole, S.W.2
  • 114
    • 33749072534 scopus 로고    scopus 로고
    • Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress
    • PID: 16946190
    • Pace TW, Mletzko TC, Alagbe O, Musselman DL, Nemeroff CB, Miller AH, Heim CM (2006) Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress. Am J Psychiatry 163:1630–1633. doi:10.1176/appi.ajp.163.9.1630
    • (2006) Am J Psychiatry , vol.163 , pp. 1630-1633
    • Pace, T.W.1    Mletzko, T.C.2    Alagbe, O.3    Musselman, D.L.4    Nemeroff, C.B.5    Miller, A.H.6    Heim, C.M.7
  • 115
    • 70149101327 scopus 로고    scopus 로고
    • Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling
    • COI: 1:CAS:528:DC%2BD1MXhtFWqs73F, PID: 19617551
    • Miller GE, Chen E, Fok AK, Walker H, Lim A, Nicholls EF, Cole S, Kobor MS (2009) Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling. Proc Natl Acad Sci USA 106:14716–14721. doi:10.1073/pnas.0902971106
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14716-14721
    • Miller, G.E.1    Chen, E.2    Fok, A.K.3    Walker, H.4    Lim, A.5    Nicholls, E.F.6    Cole, S.7    Kobor, M.S.8
  • 116
    • 77953020087 scopus 로고    scopus 로고
    • Neurohormonal and inflammatory hyper-responsiveness to acute mental stress in depression
    • PID: 20117167
    • Weinstein AA, Deuster PA, Francis JL, Bonsall RW, Tracy RP, Kop WJ (2010) Neurohormonal and inflammatory hyper-responsiveness to acute mental stress in depression. Biol Psychol 84:228–234. doi:10.1016/j.biopsycho.2010.01.016
    • (2010) Biol Psychol , vol.84 , pp. 228-234
    • Weinstein, A.A.1    Deuster, P.A.2    Francis, J.L.3    Bonsall, R.W.4    Tracy, R.P.5    Kop, W.J.6
  • 117
    • 4844227764 scopus 로고    scopus 로고
    • Antimicrobial reactive oxygen and nitrogen species: concepts and controversies
    • COI: 1:CAS:528:DC%2BD2cXns1ektLc%3D, PID: 15378046
    • Fang FC (2004) Antimicrobial reactive oxygen and nitrogen species: concepts and controversies. Nat Rev Microbiol 2:820–832. doi:10.1038/nrmicro1004
    • (2004) Nat Rev Microbiol , vol.2 , pp. 820-832
    • Fang, F.C.1
  • 118
    • 58249093636 scopus 로고    scopus 로고
    • Inflammation and oxidative stress in vertebrate host-parasite systems
    • PID: 18930878
    • Sorci G, Faivre B (2009) Inflammation and oxidative stress in vertebrate host-parasite systems. Philos Trans R Soc Lond B Biol Sci 364:71–83. doi:10.1098/rstb.2008.0151
    • (2009) Philos Trans R Soc Lond B Biol Sci , vol.364 , pp. 71-83
    • Sorci, G.1    Faivre, B.2
  • 120
    • 84943356829 scopus 로고    scopus 로고
    • Alpha7 nicotinic receptors as therapeutic targets for Parkinson’s disease
    • PID: 26093062
    • Quik M, Zhang D, McGregor M, Bordia T (2015) Alpha7 nicotinic receptors as therapeutic targets for Parkinson’s disease. Biochem Pharmacol. doi:10.1016/j.bcp.2015.06.014
    • (2015) Biochem Pharmacol.
    • Quik, M.1    Zhang, D.2    McGregor, M.3    Bordia, T.4
  • 121
    • 62949084265 scopus 로고    scopus 로고
    • Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo
    • COI: 1:CAS:528:DC%2BD1MXjslOktL8%3D, PID: 19230830
    • Bitner RS, Nikkel AL, Markosyan S, Otte S, Puttfarcken P, Gopalakrishnan M (2009) Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo. Brain Res 1265:65–74. doi:10.1016/j.brainres.2009.01.069
    • (2009) Brain Res , vol.1265 , pp. 65-74
    • Bitner, R.S.1    Nikkel, A.L.2    Markosyan, S.3    Otte, S.4    Puttfarcken, P.5    Gopalakrishnan, M.6
  • 123
    • 84904416596 scopus 로고    scopus 로고
    • Vagus nerve stimulation
    • PID: 24834378
    • Howland RH (2014) Vagus nerve stimulation. Curr Behav Neurosci Rep 1:64–73. doi:10.1007/s40473-014-0010-5
    • (2014) Curr Behav Neurosci Rep , vol.1 , pp. 64-73
    • Howland, R.H.1
  • 127
    • 71549132494 scopus 로고    scopus 로고
    • Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats
    • COI: 1:CAS:528:DC%2BD1MXhtlGitrfJ, PID: 19589349
    • Slattery DA, Neumann ID (2010) Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats. Neuropharmacology 58:56–61. doi:10.1016/j.neuropharm.2009.06.038
    • (2010) Neuropharmacology , vol.58 , pp. 56-61
    • Slattery, D.A.1    Neumann, I.D.2
  • 128
    • 0025006845 scopus 로고
    • Oxytocin excites gastric-related neurones in rat dorsal vagal complex
    • COI: 1:CAS:528:DyaK3MXktVWit7o%3D, PID: 2231433
    • McCann MJ, Rogers RC (1990) Oxytocin excites gastric-related neurones in rat dorsal vagal complex. J Physiol 428:95–108
    • (1990) J Physiol , vol.428 , pp. 95-108
    • McCann, M.J.1    Rogers, R.C.2
  • 129
    • 53149144303 scopus 로고    scopus 로고
    • Oxytocin alleviates the neuroendocrine and cytokine response to bacterial endotoxin in healthy men
    • COI: 1:CAS:528:DC%2BD1cXhtFCgt7zN, PID: 18593851
    • Clodi M, Vila G, Geyeregger R, Riedl M, Stulnig TM, Struck J, Luger TA, Luger A (2008) Oxytocin alleviates the neuroendocrine and cytokine response to bacterial endotoxin in healthy men. Am J Physiol Endocrinol Metab. 295:E686–E691. doi:10.1152/ajpendo.90263.2008
    • (2008) Am J Physiol Endocrinol Metab. , vol.295 , pp. E686-E691
    • Clodi, M.1    Vila, G.2    Geyeregger, R.3    Riedl, M.4    Stulnig, T.M.5    Struck, J.6    Luger, T.A.7    Luger, A.8
  • 130
    • 84920678605 scopus 로고    scopus 로고
    • Neuroinflammation and white matter pathology in schizophrenia: systematic review
    • PID: 24948485
    • Najjar S, Pearlman DM (2015) Neuroinflammation and white matter pathology in schizophrenia: systematic review. Schizophr Res 161:102–112. doi:10.1016/j.schres.2014.04.041
    • (2015) Schizophr Res , vol.161 , pp. 102-112
    • Najjar, S.1    Pearlman, D.M.2
  • 131
    • 84873522724 scopus 로고    scopus 로고
    • Developmental neuroinflammation and schizophrenia
    • COI: 1:CAS:528:DC%2BC3sXisVejt7o%3D, PID: 22122877
    • Meyer U (2013) Developmental neuroinflammation and schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 42:20–34. doi:10.1016/j.pnpbp.2011.11.003
    • (2013) Prog Neuropsychopharmacol Biol Psychiatry , vol.42 , pp. 20-34
    • Meyer, U.1
  • 133
    • 84938746414 scopus 로고    scopus 로고
    • Genes involved in pruning and inflammation are enriched in a large mega-sample of patients affected by schizophrenia and bipolar disorder and controls
    • PID: 26160200
    • Marco C, Antonio D, Antonina S, Alessandro S, Concetta C (2015) Genes involved in pruning and inflammation are enriched in a large mega-sample of patients affected by schizophrenia and bipolar disorder and controls. Psychiatry Res 228:945–949. doi:10.1016/j.psychres.2015.06.013
    • (2015) Psychiatry Res , vol.228 , pp. 945-949
    • Marco, C.1    Antonio, D.2    Antonina, S.3    Alessandro, S.4    Concetta, C.5
  • 136
    • 65649134782 scopus 로고    scopus 로고
    • Cytokines and schizophrenia: microglia hypothesis of schizophrenia
    • COI: 1:CAS:528:DC%2BD1MXosVentLw%3D, PID: 19579286
    • Monji A, Kato T, Kanba S (2009) Cytokines and schizophrenia: microglia hypothesis of schizophrenia. Psychiatry Clin Neurosci 63:257–265
    • (2009) Psychiatry Clin Neurosci , vol.63 , pp. 257-265
    • Monji, A.1    Kato, T.2    Kanba, S.3
  • 137
    • 80052853015 scopus 로고    scopus 로고
    • Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects
    • COI: 1:CAS:528:DC%2BC3MXhtF2jtb%2FN, PID: 21641581
    • Miller BJ, Buckley P, Seabolt W, Mellor A, Kirkpatrick B (2011) Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects. Biol Psychiatry 70:663–671. doi:10.1016/j.biopsych.2011.04.013
    • (2011) Biol Psychiatry , vol.70 , pp. 663-671
    • Miller, B.J.1    Buckley, P.2    Seabolt, W.3    Mellor, A.4    Kirkpatrick, B.5
  • 139
    • 84874216886 scopus 로고    scopus 로고
    • Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation
    • PID: 23431360, COI: 1:CAS:528:DC%2BC3sXjsFyqurw%3D
    • di Penta A, Moreno B, Reix S, Fernandez-Diez B, Villanueva M, Errea O, Escala N, Vandenbroeck K, Comella JX, Villoslada P (2013) Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation. PLoS One 8:e54722. doi:10.1371/journal.pone.0054722
    • (2013) PLoS One , vol.8 , pp. e54722
    • di Penta, A.1    Moreno, B.2    Reix, S.3    Fernandez-Diez, B.4    Villanueva, M.5    Errea, O.6    Escala, N.7    Vandenbroeck, K.8    Comella, J.X.9    Villoslada, P.10
  • 140
    • 84929321739 scopus 로고    scopus 로고
    • Altered activation of innate immunity associates with white matter volume and diffusion in first-episode psychosis
    • PID: 25970596, COI: 1:CAS:528:DC%2BC2MXhvVeitLbF
    • Mantyla T, Mantere O, Raij TT, Kieseppa T, Laitinen H, Leiviska J, Torniainen M, Tuominen L, Vaarala O, Suvisaari J (2015) Altered activation of innate immunity associates with white matter volume and diffusion in first-episode psychosis. PLoS One 10:e0125112. doi:10.1371/journal.pone.0125112
    • (2015) PLoS One , vol.10 , pp. e0125112
    • Mantyla, T.1    Mantere, O.2    Raij, T.T.3    Kieseppa, T.4    Laitinen, H.5    Leiviska, J.6    Torniainen, M.7    Tuominen, L.8    Vaarala, O.9    Suvisaari, J.10
  • 141
    • 60749117779 scopus 로고    scopus 로고
    • Citation bias in reported smoking prevalence in people with schizophrenia
    • PID: 19221917
    • Chapman S, Ragg M, McGeechan K (2009) Citation bias in reported smoking prevalence in people with schizophrenia. Aust N Z J Psychiatry 43:277–282. doi:10.1080/00048670802653372
    • (2009) Aust N Z J Psychiatry , vol.43 , pp. 277-282
    • Chapman, S.1    Ragg, M.2    McGeechan, K.3
  • 142
    • 0029085870 scopus 로고
    • Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia
    • COI: 1:CAS:528:DyaK2MXnt12mu7c%3D, PID: 7548469
    • Freedman R, Hall M, Adler LE, Leonard S (1995) Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biol Psychiatry 38:22–33. doi:10.1016/0006-3223(94)00252-X
    • (1995) Biol Psychiatry , vol.38 , pp. 22-33
    • Freedman, R.1    Hall, M.2    Adler, L.E.3    Leonard, S.4
  • 143
    • 0032872325 scopus 로고    scopus 로고
    • Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus
    • COI: 1:CAS:528:DyaK1MXmtlOhsLc%3D, PID: 10501205
    • Court J, Spurden D, Lloyd S, McKeith I, Ballard C, Cairns N, Kerwin R, Perry R, Perry E (1999) Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus. J Neurochem 73:1590–1597
    • (1999) J Neurochem , vol.73 , pp. 1590-1597
    • Court, J.1    Spurden, D.2    Lloyd, S.3    McKeith, I.4    Ballard, C.5    Cairns, N.6    Kerwin, R.7    Perry, R.8    Perry, E.9
  • 144
    • 0033519564 scopus 로고    scopus 로고
    • Decreased protein level of nicotinic receptor alpha7 subunit in the frontal cortex from schizophrenic brain
    • COI: 1:CAS:528:DyaK1MXksFalurw%3D, PID: 10501574
    • Guan ZZ, Zhang X, Blennow K, Nordberg A (1999) Decreased protein level of nicotinic receptor alpha7 subunit in the frontal cortex from schizophrenic brain. NeuroReport 10:1779–1782
    • (1999) NeuroReport , vol.10 , pp. 1779-1782
    • Guan, Z.Z.1    Zhang, X.2    Blennow, K.3    Nordberg, A.4
  • 145
    • 33745824638 scopus 로고    scopus 로고
    • Genetics of chromosome 15q13-q14 in schizophrenia
    • COI: 1:CAS:528:DC%2BD28Xmsl2jtbc%3D, PID: 16843094
    • Leonard S, Freedman R (2006) Genetics of chromosome 15q13-q14 in schizophrenia. Biol Psychiatry 60:115–122. doi:10.1016/j.biopsych.2006.03.054
    • (2006) Biol Psychiatry , vol.60 , pp. 115-122
    • Leonard, S.1    Freedman, R.2
  • 147
    • 84943362381 scopus 로고    scopus 로고
    • The human clinical phenotypes of altered CHRNA7 copy number
    • PID: 26095975
    • Gillentine MA, Schaaf CP (2015) The human clinical phenotypes of altered CHRNA7 copy number. Biochem Pharmacol. doi:10.1016/j.bcp.2015.06.012
    • (2015) Biochem Pharmacol
    • Gillentine, M.A.1    Schaaf, C.P.2
  • 148
    • 0033549478 scopus 로고    scopus 로고
    • alpha-bungarotoxin receptors contain alpha7 subunits in two different disulfide-bonded conformations
    • COI: 1:CAS:528:DyaK1MXksFCjs7k%3D, PID: 10402471
    • Rakhilin S, Drisdel RC, Sagher D, McGehee DS, Vallejo Y, Green WN (1999) alpha-bungarotoxin receptors contain alpha7 subunits in two different disulfide-bonded conformations. J Cell Biol 146:203–218
    • (1999) J Cell Biol , vol.146 , pp. 203-218
    • Rakhilin, S.1    Drisdel, R.C.2    Sagher, D.3    McGehee, D.S.4    Vallejo, Y.5    Green, W.N.6
  • 150
    • 69249212165 scopus 로고    scopus 로고
    • A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia
    • COI: 1:CAS:528:DC%2BD1MXhtVKls77L, PID: 19631623
    • Sinkus ML, Lee MJ, Gault J, Logel J, Short M, Freedman R, Christian SL, Lyon J, Leonard S (2009) A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia. Brain Res 1291:1–11. doi:10.1016/j.brainres.2009.07.041
    • (2009) Brain Res , vol.1291 , pp. 1-11
    • Sinkus, M.L.1    Lee, M.J.2    Gault, J.3    Logel, J.4    Short, M.5    Freedman, R.6    Christian, S.L.7    Lyon, J.8    Leonard, S.9
  • 151
    • 84942133427 scopus 로고    scopus 로고
    • Targeting of alpha7 nicotinic acetylcholine receptors in the treatment of schizophrenia and the use of auditory sensory gating as a translational biomarker
    • COI: 1:CAS:528:DC%2BC2MXhsFansrbK, PID: 26044974
    • Hashimoto K (2015) Targeting of alpha7 nicotinic acetylcholine receptors in the treatment of schizophrenia and the use of auditory sensory gating as a translational biomarker. Curr Pharm Des 21:3797–3806
    • (2015) Curr Pharm Des , vol.21 , pp. 3797-3806
    • Hashimoto, K.1
  • 152
    • 84940610455 scopus 로고    scopus 로고
    • The therapeutic potential of alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonists for the treatment of the cognitive deficits associated with schizophrenia
    • COI: 1:CAS:528:DC%2BC2MXhsVKitb3P, PID: 26242477
    • Beinat C, Banister SD, Herrera M, Law V, Kassiou M (2015) The therapeutic potential of alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonists for the treatment of the cognitive deficits associated with schizophrenia. CNS Drugs 29:529–542. doi:10.1007/s40263-015-0260-0
    • (2015) CNS Drugs , vol.29 , pp. 529-542
    • Beinat, C.1    Banister, S.D.2    Herrera, M.3    Law, V.4    Kassiou, M.5
  • 153
    • 84942911898 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study of encenicline, an alpha7 nicotinic acetylcholine receptor agonist, as a treatment for cognitive impairment in schizophrenia
    • Keefe RS, Meltzer HA, Dgetluck N, Gawryl M, Koenig G, Moebius HJ, Lombardo I, Hilt DC (2015) Randomized, double-blind, placebo-controlled study of encenicline, an alpha7 nicotinic acetylcholine receptor agonist, as a treatment for cognitive impairment in schizophrenia. Neuropsychopharmacology. doi:10.1038/npp.2015.176
    • (2015) Neuropsychopharmacology
    • Keefe, R.S.1    Meltzer, H.A.2    Dgetluck, N.3    Gawryl, M.4    Koenig, G.5    Moebius, H.J.6    Lombardo, I.7    Hilt, D.C.8
  • 155
    • 84900558088 scopus 로고    scopus 로고
    • A randomized, placebo-controlled study investigating the nicotinic alpha7 agonist, RG3487, for cognitive deficits in schizophrenia
    • COI: 1:CAS:528:DC%2BC2cXjtVGlsLY%3D, PID: 24549101
    • Umbricht D, Keefe RS, Murray S, Lowe DA, Porter R, Garibaldi G, Santarelli L (2014) A randomized, placebo-controlled study investigating the nicotinic alpha7 agonist, RG3487, for cognitive deficits in schizophrenia. Neuropsychopharmacology 39:1568–1577. doi:10.1038/npp.2014.17
    • (2014) Neuropsychopharmacology , vol.39 , pp. 1568-1577
    • Umbricht, D.1    Keefe, R.S.2    Murray, S.3    Lowe, D.A.4    Porter, R.5    Garibaldi, G.6    Santarelli, L.7
  • 156
    • 33750609681 scopus 로고    scopus 로고
    • Beneficial effects of ondansetron as an adjunct to haloperidol for chronic, treatment-resistant schizophrenia: a double-blind, randomized, placebo-controlled study
    • PID: 16959472
    • Zhang ZJ, Kang WH, Li Q, Wang XY, Yao SM, Ma AQ (2006) Beneficial effects of ondansetron as an adjunct to haloperidol for chronic, treatment-resistant schizophrenia: a double-blind, randomized, placebo-controlled study. Schizophr Res 88:102–110. doi:10.1016/j.schres.2006.07.010
    • (2006) Schizophr Res , vol.88 , pp. 102-110
    • Zhang, Z.J.1    Kang, W.H.2    Li, Q.3    Wang, X.Y.4    Yao, S.M.5    Ma, A.Q.6
  • 157
    • 84878590414 scopus 로고    scopus 로고
    • A randomized exploratory trial of an alpha-7 nicotinic receptor agonist (TC-5619) for cognitive enhancement in schizophrenia
    • COI: 1:CAS:528:DC%2BC3sXmt1Shu7o%3D, PID: 23303043
    • Lieberman JA, Dunbar G, Segreti AC, Girgis RR, Seoane F, Beaver JS, Duan N, Hosford DA (2013) A randomized exploratory trial of an alpha-7 nicotinic receptor agonist (TC-5619) for cognitive enhancement in schizophrenia. Neuropsychopharmacology 38:968–975. doi:10.1038/npp.2012.259
    • (2013) Neuropsychopharmacology , vol.38 , pp. 968-975
    • Lieberman, J.A.1    Dunbar, G.2    Segreti, A.C.3    Girgis, R.R.4    Seoane, F.5    Beaver, J.S.6    Duan, N.7    Hosford, D.A.8
  • 159
    • 0036038860 scopus 로고    scopus 로고
    • Study of the calcium dynamics of the human alpha4beta2, alpha3beta4 and alpha1beta1gammadelta nicotinic acetylcholine receptors
    • COI: 1:CAS:528:DC%2BD38XlvVCjs7s%3D, PID: 12172706
    • Michelmore S, Croskery K, Nozulak J, Hoyer D, Longato R, Weber A, Bouhelal R, Feuerbach D (2002) Study of the calcium dynamics of the human alpha4beta2, alpha3beta4 and alpha1beta1gammadelta nicotinic acetylcholine receptors. Naunyn Schmiedebergs Arch Pharmacol 366:235–245. doi:10.1007/s00210-002-0589-z
    • (2002) Naunyn Schmiedebergs Arch Pharmacol , vol.366 , pp. 235-245
    • Michelmore, S.1    Croskery, K.2    Nozulak, J.3    Hoyer, D.4    Longato, R.5    Weber, A.6    Bouhelal, R.7    Feuerbach, D.8
  • 160
    • 84906278089 scopus 로고    scopus 로고
    • Going up in smoke? A review of nAChRs-based treatment strategies for improving cognition in schizophrenia
    • COI: 1:CAS:528:DC%2BC2cXhsVGisr7L, PID: 24345265
    • Boggs DL, Carlson J, Cortes-Briones J, Krystal JH, D’Souza DC (2014) Going up in smoke? A review of nAChRs-based treatment strategies for improving cognition in schizophrenia. Curr Pharm Des 20:5077–5092
    • (2014) Curr Pharm Des , vol.20 , pp. 5077-5092
    • Boggs, D.L.1    Carlson, J.2    Cortes-Briones, J.3    Krystal, J.H.4    D’Souza, D.C.5
  • 162
    • 0037074248 scopus 로고    scopus 로고
    • Lotronex withdrawal
    • PID: 11784233
    • Lisi DM (2002) Lotronex withdrawal. Arch Intern Med 162:101
    • (2002) Arch Intern Med , vol.162 , pp. 101
    • Lisi, D.M.1
  • 163
    • 79953727524 scopus 로고    scopus 로고
    • Targeting the 5-HT(3) receptor in the treatment of irritable bowel syndrome
    • COI: 1:CAS:528:DC%2BC3MXks1Wqs7s%3D, PID: 21398180
    • Spiller RC (2011) Targeting the 5-HT(3) receptor in the treatment of irritable bowel syndrome. Curr Opin Pharmacol 11:68–74. doi:10.1016/j.coph.2011.02.005
    • (2011) Curr Opin Pharmacol , vol.11 , pp. 68-74
    • Spiller, R.C.1
  • 164
    • 84902578330 scopus 로고    scopus 로고
    • Profile of minocycline and its potential in the treatment of schizophrenia
    • COI: 1:CAS:528:DC%2BC2cXhslKit73L, PID: 24971013
    • Zhang L, Zhao J (2014) Profile of minocycline and its potential in the treatment of schizophrenia. Neuropsychiatr Dis Treat 10:1103–1111. doi:10.2147/NDT.S64236
    • (2014) Neuropsychiatr Dis Treat , vol.10 , pp. 1103-1111
    • Zhang, L.1    Zhao, J.2
  • 165
    • 33947116340 scopus 로고    scopus 로고
    • Bipolar disorder–focus on bipolar II disorder and mixed depression
    • PID: 17368155
    • Benazzi F (2007) Bipolar disorder–focus on bipolar II disorder and mixed depression. Lancet 369:935–945. doi:10.1016/S0140-6736(07)60453-X
    • (2007) Lancet , vol.369 , pp. 935-945
    • Benazzi, F.1
  • 166
  • 167
    • 84921888118 scopus 로고    scopus 로고
    • Integrated neurobiology of bipolar disorder
    • PID: 25202283
    • Maletic V, Raison C (2014) Integrated neurobiology of bipolar disorder. Front Psychiatry 5:98. doi:10.3389/fpsyt.2014.00098
    • (2014) Front Psychiatry , vol.5 , pp. 98
    • Maletic, V.1    Raison, C.2
  • 168
    • 84930660923 scopus 로고    scopus 로고
    • The potential role of the NLRP3 inflammasome as a link between mitochondrial complex I dysfunction and inflammation in bipolar disorder
    • PID: 26075098
    • Kim HK, Chen W, Andreazza AC (2015) The potential role of the NLRP3 inflammasome as a link between mitochondrial complex I dysfunction and inflammation in bipolar disorder. Neural Plast 2015:408136. doi:10.1155/2015/408136
    • (2015) Neural Plast , vol.2015 , pp. 408136
    • Kim, H.K.1    Chen, W.2    Andreazza, A.C.3
  • 169
    • 56349140016 scopus 로고    scopus 로고
    • Beyond genetics: childhood affective trauma in bipolar disorder
    • PID: 19594502
    • Etain B, Henry C, Bellivier F, Mathieu F, Leboyer M (2008) Beyond genetics: childhood affective trauma in bipolar disorder. Bipolar Disord 10:867–876. doi:10.1111/j.1399-5618.2008.00635.x
    • (2008) Bipolar Disord , vol.10 , pp. 867-876
    • Etain, B.1    Henry, C.2    Bellivier, F.3    Mathieu, F.4    Leboyer, M.5
  • 170
    • 34247490138 scopus 로고    scopus 로고
    • Elevated serum levels of C-reactive protein are associated with mania symptoms in outpatients with bipolar disorder
    • COI: 1:CAS:528:DC%2BD2sXkvFGktr4%3D, PID: 17391822
    • Dickerson F, Stallings C, Origoni A, Boronow J, Yolken R (2007) Elevated serum levels of C-reactive protein are associated with mania symptoms in outpatients with bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry 31:952–955. doi:10.1016/j.pnpbp.2007.02.018
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 952-955
    • Dickerson, F.1    Stallings, C.2    Origoni, A.3    Boronow, J.4    Yolken, R.5
  • 171
    • 70349562518 scopus 로고    scopus 로고
    • Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: a systematic review of the literature
    • PID: 19497250
    • Goldstein BI, Kemp DE, Soczynska JK, McIntyre RS (2009) Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: a systematic review of the literature. J Clin Psychiatry 70:1078–1090. doi:10.4088/JCP.08r04505
    • (2009) J Clin Psychiatry , vol.70 , pp. 1078-1090
    • Goldstein, B.I.1    Kemp, D.E.2    Soczynska, J.K.3    McIntyre, R.S.4
  • 172
    • 84880133128 scopus 로고    scopus 로고
    • Cytokines in bipolar disorder vs. healthy control subjects: a systematic review and meta-analysis
    • PID: 23768870
    • Munkholm K, Brauner JV, Kessing LV, Vinberg M (2013) Cytokines in bipolar disorder vs. healthy control subjects: a systematic review and meta-analysis. J Psychiatr Res 47:1119–1133. doi:10.1016/j.jpsychires.2013.05.018
    • (2013) J Psychiatr Res , vol.47 , pp. 1119-1133
    • Munkholm, K.1    Brauner, J.V.2    Kessing, L.V.3    Vinberg, M.4
  • 173
    • 84879317123 scopus 로고    scopus 로고
    • Cytokine alterations in bipolar disorder: a meta-analysis of 30 studies
    • COI: 1:CAS:528:DC%2BC3sXis1Omtrs%3D, PID: 23419545
    • Modabbernia A, Taslimi S, Brietzke E, Ashrafi M (2013) Cytokine alterations in bipolar disorder: a meta-analysis of 30 studies. Biol Psychiatry 74:15–25. doi:10.1016/j.biopsych.2013.01.007
    • (2013) Biol Psychiatry , vol.74 , pp. 15-25
    • Modabbernia, A.1    Taslimi, S.2    Brietzke, E.3    Ashrafi, M.4
  • 174
    • 84885698356 scopus 로고    scopus 로고
    • Disorders and borders: psychiatric genetics and nosology
    • PID: 24132891, COI: 1:CAS:528:DC%2BC3sXhs1GkurnF
    • Smoller JW (2013) Disorders and borders: psychiatric genetics and nosology. Am J Med Genet B Neuropsychiatr Genet 162B:559–578. doi:10.1002/ajmg.b.32174
    • (2013) Am J Med Genet B Neuropsychiatr Genet , vol.162B , pp. 559-578
    • Smoller, J.W.1
  • 175
    • 77950022786 scopus 로고    scopus 로고
    • Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients
    • COI: 1:STN:280:DC%2BC3c3gtlertg%3D%3D, PID: 19488045
    • Rao JS, Harry GJ, Rapoport SI, Kim HW (2010) Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients. Mol Psychiatry 15:384–392. doi:10.1038/mp.2009.47
    • (2010) Mol Psychiatry , vol.15 , pp. 384-392
    • Rao, J.S.1    Harry, G.J.2    Rapoport, S.I.3    Kim, H.W.4
  • 178
    • 0347914617 scopus 로고    scopus 로고
    • Association study of the human partially duplicated alpha7 nicotinic acetylcholine receptor genetic variant with bipolar disorder
    • COI: 1:CAS:528:DC%2BD2cXjsFSnug%3D%3D, PID: 14729237
    • Hong CJ, Lai IC, Liou LL, Tsai SJ (2004) Association study of the human partially duplicated alpha7 nicotinic acetylcholine receptor genetic variant with bipolar disorder. Neurosci Lett 355:69–72
    • (2004) Neurosci Lett , vol.355 , pp. 69-72
    • Hong, C.J.1    Lai, I.C.2    Liou, L.L.3    Tsai, S.J.4
  • 180
    • 22744449073 scopus 로고    scopus 로고
    • An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
    • COI: 1:CAS:528:DC%2BD2MXntFGjsLw%3D, PID: 16051150
    • Beaulieu JM, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG (2005) An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 122:261–273. doi:10.1016/j.cell.2005.05.012
    • (2005) Cell , vol.122 , pp. 261-273
    • Beaulieu, J.M.1    Sotnikova, T.D.2    Marion, S.3    Lefkowitz, R.J.4    Gainetdinov, R.R.5    Caron, M.G.6
  • 181
    • 78649908226 scopus 로고    scopus 로고
    • GSK-3beta activity and hyperdopamine-dependent behaviors
    • COI: 1:CAS:528:DC%2BC3cXhsFCrurrF, PID: 20727368
    • Li YC, Gao WJ (2011) GSK-3beta activity and hyperdopamine-dependent behaviors. Neurosci Biobehav Rev 35:645–654. doi:10.1016/j.neubiorev.2010.08.001
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 645-654
    • Li, Y.C.1    Gao, W.J.2
  • 182
    • 36048937547 scopus 로고    scopus 로고
    • Activation of glycogen synthase kinase-3 inhibits long-term potentiation with synapse-associated impairments
    • COI: 1:CAS:528:DC%2BD2sXhtlartLjE, PID: 17989287
    • Zhu LQ, Wang SH, Liu D, Yin YY, Tian Q, Wang XC, Wang Q, Chen JG, Wang JZ (2007) Activation of glycogen synthase kinase-3 inhibits long-term potentiation with synapse-associated impairments. J Neurosci 27:12211–12220. doi:10.1523/JNEUROSCI.3321-07.2007
    • (2007) J Neurosci , vol.27 , pp. 12211-12220
    • Zhu, L.Q.1    Wang, S.H.2    Liu, D.3    Yin, Y.Y.4    Tian, Q.5    Wang, X.C.6    Wang, Q.7    Chen, J.G.8    Wang, J.Z.9
  • 185
    • 78649683404 scopus 로고    scopus 로고
    • Neurogenetics and pharmacology of learning, motivation, and cognition
    • PID: 20631684
    • Frank MJ, Fossella JA (2011) Neurogenetics and pharmacology of learning, motivation, and cognition. Neuropsychopharmacology 36:133–152. doi:10.1038/npp.2010.96
    • (2011) Neuropsychopharmacology , vol.36 , pp. 133-152
    • Frank, M.J.1    Fossella, J.A.2
  • 186
    • 84890879661 scopus 로고    scopus 로고
    • Cortical synaptic NMDA receptor deficits in alpha7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases
    • COI: 1:CAS:528:DC%2BC2cXhtFOisrk%3D, PID: 24326163
    • Lin H, Hsu FC, Baumann BH, Coulter DA, Lynch DR (2014) Cortical synaptic NMDA receptor deficits in alpha7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases. Neurobiol Dis 63:129–140. doi:10.1016/j.nbd.2013.11.021
    • (2014) Neurobiol Dis , vol.63 , pp. 129-140
    • Lin, H.1    Hsu, F.C.2    Baumann, B.H.3    Coulter, D.A.4    Lynch, D.R.5
  • 189
    • 84884595346 scopus 로고    scopus 로고
    • Genome-wide gene expression in a patient with 15q13.3 homozygous microdeletion syndrome
    • PID: 23361223, COI: 1:CAS:528:DC%2BC3sXhsV2js73N
    • Le Pichon JB, Yu S, Kibiryeva N, Graf WD, Bittel DC (2013) Genome-wide gene expression in a patient with 15q13.3 homozygous microdeletion syndrome. Eur J Hum Genet 21:1093–1099. doi:10.1038/ejhg.2013.1
    • (2013) Eur J Hum Genet , vol.21 , pp. 1093-1099
    • Le Pichon, J.B.1    Yu, S.2    Kibiryeva, N.3    Graf, W.D.4    Bittel, D.C.5
  • 190
    • 84902585877 scopus 로고    scopus 로고
    • Galantamine efficacy and tolerability as an augmentative therapy in autistic children: a randomized, double-blind, placebo-controlled trial
    • PID: 24132248, COI: 1:CAS:528:DC%2BC2cXhslWgsbbO
    • Ghaleiha A, Ghyasvand M, Mohammadi MR, Farokhnia M, Yadegari N, Tabrizi M, Hajiaghaee R, Yekehtaz H, Akhondzadeh S (2013) Galantamine efficacy and tolerability as an augmentative therapy in autistic children: a randomized, double-blind, placebo-controlled trial. J Psychopharmacol 28:677–685. doi:10.1177/0269881113508830
    • (2013) J Psychopharmacol , vol.28 , pp. 677-685
    • Ghaleiha, A.1    Ghyasvand, M.2    Mohammadi, M.R.3    Farokhnia, M.4    Yadegari, N.5    Tabrizi, M.6    Hajiaghaee, R.7    Yekehtaz, H.8    Akhondzadeh, S.9
  • 193
    • 0036247211 scopus 로고    scopus 로고
    • Cytokines and chemoattractants in allergic inflammation
    • COI: 1:CAS:528:DC%2BD38XjsFClt7g%3D, PID: 12009564
    • Romagnani S (2002) Cytokines and chemoattractants in allergic inflammation. Mol Immunol 38:881–885
    • (2002) Mol Immunol , vol.38 , pp. 881-885
    • Romagnani, S.1
  • 194
    • 29244453650 scopus 로고    scopus 로고
    • T-helper cell type-2 regulation in allergic disease
    • COI: 1:CAS:528:DC%2BD28Xms1Srug%3D%3D, PID: 16319345
    • Georas SN, Guo J, De Fanis U, Casolaro V (2005) T-helper cell type-2 regulation in allergic disease. Eur Respir J 26:1119–1137. doi:10.1183/09031936.05.00006005
    • (2005) Eur Respir J , vol.26 , pp. 1119-1137
    • Georas, S.N.1    Guo, J.2    De Fanis, U.3    Casolaro, V.4
  • 195
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: in vivo veritas
    • COI: 1:CAS:528:DC%2BC38XjsV2ms7g%3D, PID: 22378047
    • Sica A, Mantovani A (2012) Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 122:787–795. doi:10.1172/JCI59643
    • (2012) J Clin Invest , vol.122 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 196
    • 84920717602 scopus 로고    scopus 로고
    • Microglial and macrophage polarization-new prospects for brain repair
    • PID: 25385337
    • Hu X, Leak RK, Shi Y, Suenaga J, Gao Y, Zheng P, Chen J (2015) Microglial and macrophage polarization-new prospects for brain repair. Nat Rev Neurol 11:56–64. doi:10.1038/nrneurol.2014.207
    • (2015) Nat Rev Neurol , vol.11 , pp. 56-64
    • Hu, X.1    Leak, R.K.2    Shi, Y.3    Suenaga, J.4    Gao, Y.5    Zheng, P.6    Chen, J.7
  • 197
    • 84923384915 scopus 로고    scopus 로고
    • Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism
    • COI: 1:CAS:528:DC%2BC2MXjvFajs7w%3D, PID: 25494366
    • Gupta S, Ellis SE, Ashar FN, Moes A, Bader JS, Zhan J, West AB, Arking DE (2014) Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism. Nat Commun 5:5748. doi:10.1038/ncomms6748
    • (2014) Nat Commun , vol.5 , pp. 5748
    • Gupta, S.1    Ellis, S.E.2    Ashar, F.N.3    Moes, A.4    Bader, J.S.5    Zhan, J.6    West, A.B.7    Arking, D.E.8
  • 198
    • 16844385525 scopus 로고    scopus 로고
    • Depression in multiple sclerosis: a review
    • COI: 1:STN:280:DC%2BD2M7ktlelsg%3D%3D, PID: 15774430
    • Siegert RJ, Abernethy DA (2005) Depression in multiple sclerosis: a review. J Neurol Neurosurg Psychiatry 76:469–475. doi:10.1136/jnnp.2004.054635
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 469-475
    • Siegert, R.J.1    Abernethy, D.A.2
  • 199
    • 84862635336 scopus 로고    scopus 로고
    • Will the real multiple sclerosis please stand up?
    • COI: 1:CAS:528:DC%2BC38XovVamu78%3D, PID: 22714021
    • Stys PK, Zamponi GW, van Minnen J, Geurts JJ (2012) Will the real multiple sclerosis please stand up? Nat Rev Neurosci 13:507–514. doi:10.1038/nrn3275
    • (2012) Nat Rev Neurosci , vol.13 , pp. 507-514
    • Stys, P.K.1    Zamponi, G.W.2    van Minnen, J.3    Geurts, J.J.4
  • 200
    • 33645376448 scopus 로고    scopus 로고
    • Immunopathogenesis and immunotherapy of multiple sclerosis
    • COI: 1:CAS:528:DC%2BD28XktlyqsLk%3D, PID: 16932551
    • Hemmer B, Nessler S, Zhou D, Kieseier B, Hartung HP (2006) Immunopathogenesis and immunotherapy of multiple sclerosis. Nat Clin Pract Neurol 2:201–211. doi:10.1038/ncpneuro0154
    • (2006) Nat Clin Pract Neurol , vol.2 , pp. 201-211
    • Hemmer, B.1    Nessler, S.2    Zhou, D.3    Kieseier, B.4    Hartung, H.P.5
  • 201
    • 77649341442 scopus 로고    scopus 로고
    • Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses
    • COI: 1:CAS:528:DC%2BD1MXhtlKhtrzM, PID: 19846875
    • Nizri E, Irony-Tur-Sinai M, Lory O, Orr-Urtreger A, Lavi E, Brenner T (2009) Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses. J Immunol. 183:6681–6688. doi:10.4049/jimmunol.0902212
    • (2009) J Immunol. , vol.183 , pp. 6681-6688
    • Nizri, E.1    Irony-Tur-Sinai, M.2    Lory, O.3    Orr-Urtreger, A.4    Lavi, E.5    Brenner, T.6
  • 202
    • 33645078446 scopus 로고    scopus 로고
    • Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways
    • COI: 1:STN:280:DC%2BD2Mnmt1Ggtw%3D%3D, PID: 16344512
    • Hilker R, Thomas AV, Klein JC, Weisenbach S, Kalbe E, Burghaus L, Jacobs AH, Herholz K, Heiss WD (2005) Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways. Neurology 65:1716–1722. doi:10.1212/01.wnl.0000191154.78131.f6
    • (2005) Neurology , vol.65 , pp. 1716-1722
    • Hilker, R.1    Thomas, A.V.2    Klein, J.C.3    Weisenbach, S.4    Kalbe, E.5    Burghaus, L.6    Jacobs, A.H.7    Herholz, K.8    Heiss, W.D.9
  • 204
    • 0347385143 scopus 로고    scopus 로고
    • Cortical cholinergic function is more severely affected in parkinsonian dementia than in Alzheimer disease: an in vivo positron emission tomographic study
    • PID: 14676050
    • Bohnen NI, Kaufer DI, Ivanco LS, Lopresti B, Koeppe RA, Davis JG, Mathis CA, Moore RY, DeKosky ST (2003) Cortical cholinergic function is more severely affected in parkinsonian dementia than in Alzheimer disease: an in vivo positron emission tomographic study. Arch Neurol 60:1745–1748. doi:10.1001/archneur.60.12.1745
    • (2003) Arch Neurol , vol.60 , pp. 1745-1748
    • Bohnen, N.I.1    Kaufer, D.I.2    Ivanco, L.S.3    Lopresti, B.4    Koeppe, R.A.5    Davis, J.G.6    Mathis, C.A.7    Moore, R.Y.8    DeKosky, S.T.9
  • 206
    • 84880200169 scopus 로고    scopus 로고
    • The alpha7 nAChR agonist PNU-282987 reduces inflammation and MPTP-induced nigral dopaminergic cell loss in mice
    • COI: 1:CAS:528:DC%2BC3sXhtFygs73E, PID: 23938346
    • Stuckenholz V, Bacher M, Balzer-Geldsetzer M, Alvarez-Fischer D, Oertel WH, Dodel RC, Noelker C (2013) The alpha7 nAChR agonist PNU-282987 reduces inflammation and MPTP-induced nigral dopaminergic cell loss in mice. J Parkinsons Dis 3:161–172. doi:10.3233/JPD-120157
    • (2013) J Parkinsons Dis , vol.3 , pp. 161-172
    • Stuckenholz, V.1    Bacher, M.2    Balzer-Geldsetzer, M.3    Alvarez-Fischer, D.4    Oertel, W.H.5    Dodel, R.C.6    Noelker, C.7
  • 207
    • 84872618423 scopus 로고    scopus 로고
    • 3-[(2,4-Dimethoxy)benzylidene]-anabaseine dihydrochloride protects against 6-hydroxydopamine-induced parkinsonian neurodegeneration through alpha7 nicotinic acetylcholine receptor stimulation in rats
    • COI: 1:CAS:528:DC%2BC38XhvVektb7F, PID: 23239187
    • Suzuki S, Kawamata J, Matsushita T, Matsumura A, Hisahara S, Takata K, Kitamura Y, Kem W, Shimohama S (2013) 3-[(2,4-Dimethoxy)benzylidene]-anabaseine dihydrochloride protects against 6-hydroxydopamine-induced parkinsonian neurodegeneration through alpha7 nicotinic acetylcholine receptor stimulation in rats. J Neurosci Res 91:462–471. doi:10.1002/jnr.23160
    • (2013) J Neurosci Res , vol.91 , pp. 462-471
    • Suzuki, S.1    Kawamata, J.2    Matsushita, T.3    Matsumura, A.4    Hisahara, S.5    Takata, K.6    Kitamura, Y.7    Kem, W.8    Shimohama, S.9
  • 208
    • 84920748280 scopus 로고    scopus 로고
    • Activation of alpha7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: implications for Parkinson’s disease
    • COI: 1:CAS:528:DC%2BC2cXitVygsb7P, PID: 25486621
    • Liu Y, Zeng X, Hui Y, Zhu C, Wu J, Taylor DH, Ji J, Fan W, Huang Z, Hu J (2015) Activation of alpha7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: implications for Parkinson’s disease. Neuropharmacology 91:87–96. doi:10.1016/j.neuropharm.2014.11.028
    • (2015) Neuropharmacology , vol.91 , pp. 87-96
    • Liu, Y.1    Zeng, X.2    Hui, Y.3    Zhu, C.4    Wu, J.5    Taylor, D.H.6    Ji, J.7    Fan, W.8    Huang, Z.9    Hu, J.10
  • 209
    • 34347218938 scopus 로고    scopus 로고
    • Nigrostriatal damage preferentially decreases a subpopulation of alpha6beta2* nAChRs in mouse, monkey, and Parkinson’s disease striatum
    • COI: 1:CAS:528:DC%2BD2sXnsVyjsL4%3D, PID: 17409284
    • Bordia T, Grady SR, McIntosh JM, Quik M (2007) Nigrostriatal damage preferentially decreases a subpopulation of alpha6beta2* nAChRs in mouse, monkey, and Parkinson’s disease striatum. Mol Pharmacol 72:52–61. doi:10.1124/mol.107.035998
    • (2007) Mol Pharmacol , vol.72 , pp. 52-61
    • Bordia, T.1    Grady, S.R.2    McIntosh, J.M.3    Quik, M.4
  • 210
    • 62549133546 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson’s disease: a target for neuroprotection?
    • COI: 1:CAS:528:DC%2BD1MXks1Sis70%3D, PID: 19296921
    • Hirsch EC, Hunot S (2009) Neuroinflammation in Parkinson’s disease: a target for neuroprotection? Lancet Neurol 8:382–397. doi:10.1016/S1474-4422(09)70062-6
    • (2009) Lancet Neurol , vol.8 , pp. 382-397
    • Hirsch, E.C.1    Hunot, S.2
  • 211
    • 84555189257 scopus 로고    scopus 로고
    • Depression in Parkinson disease—epidemiology, mechanisms and management
    • COI: 1:CAS:528:DC%2BC3MXhs1OltrbI
    • Aarsland D, Pahlhagen S, Ballard CG, Ehrt U, Svenningsson P (2012) Depression in Parkinson disease—epidemiology, mechanisms and management. Nat Rev Neurol 8:35–47. doi:10.1038/nrneurol.2011.189
    • (2012) Nat Rev Neurol , vol.8 , pp. 35-47
    • Aarsland, D.1    Pahlhagen, S.2    Ballard, C.G.3    Ehrt, U.4    Svenningsson, P.5
  • 212
    • 77958153385 scopus 로고    scopus 로고
    • Occurrence of depression and anxiety prior to Parkinson’s disease
    • COI: 1:STN:280:DC%2BC3cbhsVCquw%3D%3D, PID: 20674460
    • Jacob EL, Gatto NM, Thompson A, Bordelon Y, Ritz B (2010) Occurrence of depression and anxiety prior to Parkinson’s disease. Parkinsonism Relat Disord 16:576–581. doi:10.1016/j.parkreldis.2010.06.014
    • (2010) Parkinsonism Relat Disord , vol.16 , pp. 576-581
    • Jacob, E.L.1    Gatto, N.M.2    Thompson, A.3    Bordelon, Y.4    Ritz, B.5
  • 213
    • 84867629199 scopus 로고    scopus 로고
    • Non-motor symptoms in patients with Parkinson’s disease—correlations with inflammatory cytokines in serum
    • COI: 1:CAS:528:DC%2BC38Xhs1WhurvO, PID: 23082161
    • Lindqvist D, Kaufman E, Brundin L, Hall S, Surova Y, Hansson O (2012) Non-motor symptoms in patients with Parkinson’s disease—correlations with inflammatory cytokines in serum. PLoS One 7:e47387. doi:10.1371/journal.pone.0047387
    • (2012) PLoS One , vol.7 , pp. e47387
    • Lindqvist, D.1    Kaufman, E.2    Brundin, L.3    Hall, S.4    Surova, Y.5    Hansson, O.6
  • 215
    • 0842324690 scopus 로고    scopus 로고
    • Differences in alpha7 nicotinic acetylcholine receptor binding in motor symptomatic and asymptomatic MPTP-treated monkeys
    • COI: 1:CAS:528:DC%2BD2cXpsVygsg%3D%3D, PID: 14759498
    • Kulak JM, Schneider JS (2004) Differences in alpha7 nicotinic acetylcholine receptor binding in motor symptomatic and asymptomatic MPTP-treated monkeys. Brain Res 999:193–202. doi:10.1016/j.brainres.2003.10.062
    • (2004) Brain Res , vol.999 , pp. 193-202
    • Kulak, J.M.1    Schneider, J.S.2
  • 217
    • 84882571292 scopus 로고    scopus 로고
    • Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration
    • COI: 1:CAS:528:DC%2BC3sXhtlSit7vP, PID: 23732506
    • Perry VH, Teeling J (2013) Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration. Semin Immunopathol 35:601–612. doi:10.1007/s00281-013-0382-8
    • (2013) Semin Immunopathol , vol.35 , pp. 601-612
    • Perry, V.H.1    Teeling, J.2
  • 218
    • 58749093072 scopus 로고    scopus 로고
    • IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1–42) by rat primary type 2 microglia
    • COI: 1:CAS:528:DC%2BD1cXht1Krt77N, PID: 18941241
    • Shimizu E, Kawahara K, Kajizono M, Sawada M, Nakayama H (2008) IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1–42) by rat primary type 2 microglia. J Immunol 181:6503–6513
    • (2008) J Immunol , vol.181 , pp. 6503-6513
    • Shimizu, E.1    Kawahara, K.2    Kajizono, M.3    Sawada, M.4    Nakayama, H.5
  • 219
    • 84881251933 scopus 로고    scopus 로고
    • Microglia during development and aging
    • COI: 1:CAS:528:DC%2BC3sXnvVGqtrg%3D, PID: 23644076
    • Harry GJ (2013) Microglia during development and aging. Pharmacol Ther 139:313–326. doi:10.1016/j.pharmthera.2013.04.013
    • (2013) Pharmacol Ther , vol.139 , pp. 313-326
    • Harry, G.J.1
  • 220
    • 77249153190 scopus 로고    scopus 로고
    • Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3cXisVKlsb0%3D, PID: 20164328
    • Hernandez CM, Kayed R, Zheng H, Sweatt JD, Dineley KT (2010) Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer’s disease. J Neurosci 30:2442–2453. doi:10.1523/JNEUROSCI.5038-09.2010
    • (2010) J Neurosci , vol.30 , pp. 2442-2453
    • Hernandez, C.M.1    Kayed, R.2    Zheng, H.3    Sweatt, J.D.4    Dineley, K.T.5
  • 221
    • 84928905831 scopus 로고    scopus 로고
    • Smoking is associated with an increased risk of dementia: a meta-analysis of prospective cohort studies with investigation of potential effect modifiers
    • PID: 25763939, COI: 1:CAS:528:DC%2BC2MXhs1SjsLrE
    • Zhong G, Wang Y, Zhang Y, Guo JJ, Zhao Y (2015) Smoking is associated with an increased risk of dementia: a meta-analysis of prospective cohort studies with investigation of potential effect modifiers. PLoS One 10:e0118333. doi:10.1371/journal.pone.0118333
    • (2015) PLoS One , vol.10 , pp. e0118333
    • Zhong, G.1    Wang, Y.2    Zhang, Y.3    Guo, J.J.4    Zhao, Y.5
  • 222
    • 0033842094 scopus 로고    scopus 로고
    • Smoking and Parkinson’s and Alzheimer’s disease: review of the epidemiological studies
    • COI: 1:CAS:528:DC%2BD3cXlvFGmsLc%3D, PID: 10942038
    • Fratiglioni L, Wang HX (2000) Smoking and Parkinson’s and Alzheimer’s disease: review of the epidemiological studies. Behav Brain Res 113:117–120
    • (2000) Behav Brain Res , vol.113 , pp. 117-120
    • Fratiglioni, L.1    Wang, H.X.2
  • 223
    • 80052033738 scopus 로고    scopus 로고
    • Research update: alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3MXhtVKksLnK, PID: 21763291
    • Parri HR, Hernandez CM, Dineley KT (2011) Research update: alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer’s disease. Biochem Pharmacol 82:931–942. doi:10.1016/j.bcp.2011.06.039
    • (2011) Biochem Pharmacol , vol.82 , pp. 931-942
    • Parri, H.R.1    Hernandez, C.M.2    Dineley, K.T.3
  • 224
    • 59649090731 scopus 로고    scopus 로고
    • A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides
    • COI: 1:CAS:528:DC%2BD1MXhs1KqsLc%3D, PID: 19176801
    • Liu Q, Huang Y, Xue F, Simard A, DeChon J, Li G, Zhang J, Lucero L, Wang M, Sierks M, Hu G, Chang Y, Lukas RJ, Wu J (2009) A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. J Neurosci 29:918–929. doi:10.1523/JNEUROSCI.3952-08.2009
    • (2009) J Neurosci , vol.29 , pp. 918-929
    • Liu, Q.1    Huang, Y.2    Xue, F.3    Simard, A.4    DeChon, J.5    Li, G.6    Zhang, J.7    Lucero, L.8    Wang, M.9    Sierks, M.10    Hu, G.11    Chang, Y.12    Lukas, R.J.13    Wu, J.14
  • 225
    • 84939248743 scopus 로고    scopus 로고
    • alpha7 and beta2 nicotinic acetylcholine receptor subunits form heteromeric receptor complexes that are expressed in the human cortex and display distinct pharmacological properties
    • PID: 26086615, COI: 1:CAS:528:DC%2BC28XnslOqsLo%3D
    • Thomsen MS, Zwart R, Ursu D, Jensen MM, Pinborg LH, Gilmour G, Wu J, Sher E, Mikkelsen JD (2015) alpha7 and beta2 nicotinic acetylcholine receptor subunits form heteromeric receptor complexes that are expressed in the human cortex and display distinct pharmacological properties. PLoS One 10:e0130572. doi:10.1371/journal.pone.0130572
    • (2015) PLoS One , vol.10 , pp. e0130572
    • Thomsen, M.S.1    Zwart, R.2    Ursu, D.3    Jensen, M.M.4    Pinborg, L.H.5    Gilmour, G.6    Wu, J.7    Sher, E.8    Mikkelsen, J.D.9
  • 226
    • 84882579816 scopus 로고    scopus 로고
    • Emerging approaches for treatment of schizophrenia: modulation of cholinergic signaling
    • PID: 23272693
    • Foster DJ, Jones CK, Conn PJ (2012) Emerging approaches for treatment of schizophrenia: modulation of cholinergic signaling. Discov Med 14:413–420
    • (2012) Discov Med , vol.14 , pp. 413-420
    • Foster, D.J.1    Jones, C.K.2    Conn, P.J.3
  • 227
    • 84555217920 scopus 로고    scopus 로고
    • alpha7 Nicotinic receptor modulators for cognitive deficits in schizophrenia and Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3MXhs1KrsrvI, PID: 22047592
    • Geerts H (2012) alpha7 Nicotinic receptor modulators for cognitive deficits in schizophrenia and Alzheimer’s disease. Expert Opin Investig Drugs 21:59–65. doi:10.1517/13543784.2012.633510
    • (2012) Expert Opin Investig Drugs , vol.21 , pp. 59-65
    • Geerts, H.1
  • 228
    • 84922005166 scopus 로고    scopus 로고
    • Targeting brain alpha7 nicotinic acetylcholine receptors in Alzheimer’s disease: rationale and current status
    • COI: 1:CAS:528:DC%2BC2cXhs1OhsrjN, PID: 25248971
    • Valles AS, Borroni MV, Barrantes FJ (2014) Targeting brain alpha7 nicotinic acetylcholine receptors in Alzheimer’s disease: rationale and current status. CNS Drugs 28:975–987. doi:10.1007/s40263-014-0201-3
    • (2014) CNS Drugs , vol.28 , pp. 975-987
    • Valles, A.S.1    Borroni, M.V.2    Barrantes, F.J.3
  • 230
    • 58049109125 scopus 로고    scopus 로고
    • The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain
    • COI: 1:CAS:528:DC%2BD1MXhsVGltg%3D%3D, PID: 18793655
    • Feuerbach D, Lingenhoehl K, Olpe HR, Vassout A, Gentsch C, Chaperon F, Nozulak J, Enz A, Bilbe G, McAllister K, Hoyer D (2009) The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain. Neuropharmacology 56:254–263. doi:10.1016/j.neuropharm.2008.08.025
    • (2009) Neuropharmacology , vol.56 , pp. 254-263
    • Feuerbach, D.1    Lingenhoehl, K.2    Olpe, H.R.3    Vassout, A.4    Gentsch, C.5    Chaperon, F.6    Nozulak, J.7    Enz, A.8    Bilbe, G.9    McAllister, K.10    Hoyer, D.11
  • 231
    • 77956169569 scopus 로고    scopus 로고
    • Continuous administration of a selective alpha7 nicotinic partial agonist, DMXBA, improves sensory inhibition without causing tachyphylaxis or receptor upregulation in DBA/2 mice
    • COI: 1:CAS:528:DC%2BC3cXhtVKisLrN, PID: 20599427
    • Stevens KE, Cornejo B, Adams CE, Zheng L, Yonchek J, Hoffman KL, Christians U, Kem WR (2010) Continuous administration of a selective alpha7 nicotinic partial agonist, DMXBA, improves sensory inhibition without causing tachyphylaxis or receptor upregulation in DBA/2 mice. Brain Res 1352:140–146. doi:10.1016/j.brainres.2010.06.063
    • (2010) Brain Res , vol.1352 , pp. 140-146
    • Stevens, K.E.1    Cornejo, B.2    Adams, C.E.3    Zheng, L.4    Yonchek, J.5    Hoffman, K.L.6    Christians, U.7    Kem, W.R.8
  • 233
    • 0034731873 scopus 로고    scopus 로고
    • alpha7 receptor-selective agonists and modes of alpha7 receptor activation
    • COI: 1:CAS:528:DC%2BD3cXisFKjsrk%3D, PID: 10771012
    • Papke RL, Meyer E, Nutter T, Uteshev VV (2000) alpha7 receptor-selective agonists and modes of alpha7 receptor activation. Eur J Pharmacol 393:179–195
    • (2000) Eur J Pharmacol , vol.393 , pp. 179-195
    • Papke, R.L.1    Meyer, E.2    Nutter, T.3    Uteshev, V.V.4
  • 235
    • 77952386905 scopus 로고    scopus 로고
    • Different interaction between the agonist JN403 and the competitive antagonist methyllycaconitine with the human alpha7 nicotinic acetylcholine receptor
    • COI: 1:CAS:528:DC%2BC3cXltVGjtLg%3D, PID: 20377277
    • Arias HR, Gu RX, Feuerbach D, Wei DQ (2010) Different interaction between the agonist JN403 and the competitive antagonist methyllycaconitine with the human alpha7 nicotinic acetylcholine receptor. Biochemistry 49:4169–4180. doi:10.1021/bi901999v
    • (2010) Biochemistry , vol.49 , pp. 4169-4180
    • Arias, H.R.1    Gu, R.X.2    Feuerbach, D.3    Wei, D.Q.4
  • 236
    • 84855964150 scopus 로고    scopus 로고
    • EVP-6124, a novel and selective alpha7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of alpha7 nicotinic acetylcholine receptors
    • COI: 1:CAS:528:DC%2BC38XhtFClu7c%3D, PID: 22085888
    • Prickaerts J, van Goethem NP, Chesworth R, Shapiro G, Boess FG, Methfessel C, Reneerkens OA, Flood DG, Hilt D, Gawryl M, Bertrand S, Bertrand D, Konig G (2012) EVP-6124, a novel and selective alpha7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of alpha7 nicotinic acetylcholine receptors. Neuropharmacology 62:1099–1110. doi:10.1016/j.neuropharm.2011.10.024
    • (2012) Neuropharmacology , vol.62 , pp. 1099-1110
    • Prickaerts, J.1    van Goethem, N.P.2    Chesworth, R.3    Shapiro, G.4    Boess, F.G.5    Methfessel, C.6    Reneerkens, O.A.7    Flood, D.G.8    Hilt, D.9    Gawryl, M.10    Bertrand, S.11    Bertrand, D.12    Konig, G.13
  • 237
    • 0028584175 scopus 로고
    • Unusual pharmacology of (+)-tubocurarine with rat neuronal nicotinic acetylcholine receptors containing beta 4 subunits
    • COI: 1:CAS:528:DyaK2MXivFKqt7s%3D, PID: 7808438
    • Cachelin AB, Rust G (1994) Unusual pharmacology of (+)-tubocurarine with rat neuronal nicotinic acetylcholine receptors containing beta 4 subunits. Mol Pharmacol 46:1168–1174
    • (1994) Mol Pharmacol , vol.46 , pp. 1168-1174
    • Cachelin, A.B.1    Rust, G.2
  • 238
    • 84892374904 scopus 로고    scopus 로고
    • The neuroimmunology of schizophrenia
    • COI: 1:CAS:528:DC%2BC2cXjsVegu7g%3D, PID: 24465246
    • Smyth AM, Lawrie SM (2013) The neuroimmunology of schizophrenia. Clin Psychopharmacol Neurosci 11:107–117. doi:10.9758/cpn.2013.11.3.107
    • (2013) Clin Psychopharmacol Neurosci , vol.11 , pp. 107-117
    • Smyth, A.M.1    Lawrie, S.M.2
  • 239
    • 35848950202 scopus 로고    scopus 로고
    • Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia and depression is associated with suicide
    • PID: 17174336
    • Steiner J, Bielau H, Brisch R, Danos P, Ullrich O, Mawrin C, Bernstein HG, Bogerts B (2008) Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia and depression is associated with suicide. J Psychiatr Res 42:151–157. doi:10.1016/j.jpsychires.2006.10.013
    • (2008) J Psychiatr Res , vol.42 , pp. 151-157
    • Steiner, J.1    Bielau, H.2    Brisch, R.3    Danos, P.4    Ullrich, O.5    Mawrin, C.6    Bernstein, H.G.7    Bogerts, B.8
  • 240
    • 78651451984 scopus 로고    scopus 로고
    • Cytokine levels in the blood may distinguish suicide attempters from depressed patients
    • COI: 1:CAS:528:DC%2BC3MXhtVSqsrg%3D, PID: 20951793
    • Janelidze S, Mattei D, Westrin A, Traskman-Bendz L, Brundin L (2011) Cytokine levels in the blood may distinguish suicide attempters from depressed patients. Brain Behav Immun 25:335–339. doi:10.1016/j.bbi.2010.10.010
    • (2011) Brain Behav Immun , vol.25 , pp. 335-339
    • Janelidze, S.1    Mattei, D.2    Westrin, A.3    Traskman-Bendz, L.4    Brundin, L.5
  • 244
    • 84856702223 scopus 로고    scopus 로고
    • Inhibition of GSK3 by lithium, from single molecules to signaling networks
    • COI: 1:CAS:528:DC%2BC38Xjt1KksL4%3D, PID: 22363263
    • Freland L, Beaulieu JM (2012) Inhibition of GSK3 by lithium, from single molecules to signaling networks. Front Mol Neurosci 5:14. doi:10.3389/fnmol.2012.00014
    • (2012) Front Mol Neurosci , vol.5 , pp. 14
    • Freland, L.1    Beaulieu, J.M.2
  • 245
    • 73149097234 scopus 로고    scopus 로고
    • Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)
    • COI: 1:CAS:528:DC%2BC3cXkt1ejtg%3D%3D, PID: 19836308
    • Beurel E, Michalek SM, Jope RS (2010) Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3). Trends Immunol 31:24–31. doi:10.1016/j.it.2009.09.007
    • (2010) Trends Immunol , vol.31 , pp. 24-31
    • Beurel, E.1    Michalek, S.M.2    Jope, R.S.3
  • 246
    • 0038642174 scopus 로고    scopus 로고
    • Lithium treatment and suicide risk in major affective disorders: update and new findings
    • COI: 1:CAS:528:DC%2BD3sXktVOmt70%3D, PID: 12720484
    • Baldessarini RJ, Tondo L, Hennen J (2003) Lithium treatment and suicide risk in major affective disorders: update and new findings. J Clin Psychiatry 64(Suppl 5):44–52
    • (2003) J Clin Psychiatry , vol.64 , pp. 44-52
    • Baldessarini, R.J.1    Tondo, L.2    Hennen, J.3
  • 247
    • 84927785897 scopus 로고    scopus 로고
    • Inflammation and lithium: clues to mechanisms contributing to suicide-linked traits
    • COI: 1:CAS:528:DC%2BC2cXitFyhurbO, PID: 25514751
    • Beurel E, Jope RS (2014) Inflammation and lithium: clues to mechanisms contributing to suicide-linked traits. Transl Psychiatry 4:e488. doi:10.1038/tp.2014.129
    • (2014) Transl Psychiatry , vol.4 , pp. e488
    • Beurel, E.1    Jope, R.S.2
  • 248
    • 47949096771 scopus 로고    scopus 로고
    • Lithium prevents and ameliorates experimental autoimmune encephalomyelitis
    • PID: 18566399
    • De Sarno P, Axtell RC, Raman C, Roth KA, Alessi DR, Jope RS (2008) Lithium prevents and ameliorates experimental autoimmune encephalomyelitis. J Immunol 181:338–345
    • (2008) J Immunol , vol.181 , pp. 338-345
    • De Sarno, P.1    Axtell, R.C.2    Raman, C.3    Roth, K.A.4    Alessi, D.R.5    Jope, R.S.6
  • 249
    • 33646922314 scopus 로고    scopus 로고
    • Full reversal of Alzheimer’s disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3
    • COI: 1:CAS:528:DC%2BD28Xlt1CjurY%3D, PID: 16687499
    • Engel T, Hernandez F, Avila J, Lucas JJ (2006) Full reversal of Alzheimer’s disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3. J Neurosci 26:5083–5090. doi:10.1523/JNEUROSCI.0604-06.2006
    • (2006) J Neurosci , vol.26 , pp. 5083-5090
    • Engel, T.1    Hernandez, F.2    Avila, J.3    Lucas, J.J.4
  • 250
    • 78650904823 scopus 로고    scopus 로고
    • Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice
    • COI: 1:CAS:528:DC%2BC3MXntlOk, PID: 21187954
    • Fiorentini A, Rosi MC, Grossi C, Luccarini I, Casamenti F (2010) Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice. PLoS One 5:e14382. doi:10.1371/journal.pone.0014382
    • (2010) PLoS One , vol.5 , pp. e14382
    • Fiorentini, A.1    Rosi, M.C.2    Grossi, C.3    Luccarini, I.4    Casamenti, F.5
  • 251
    • 79959276349 scopus 로고    scopus 로고
    • Long-term treatment with lithium alleviates memory deficits and reduces amyloid-beta production in an aged Alzheimer’s disease transgenic mouse model
    • COI: 1:CAS:528:DC%2BC3MXovFyrsrk%3D, PID: 21321394
    • Zhang X, Heng X, Li T, Li L, Yang D, Zhang X, Du Y, Doody RS, Le W (2011) Long-term treatment with lithium alleviates memory deficits and reduces amyloid-beta production in an aged Alzheimer’s disease transgenic mouse model. J Alzheimers Dis 24:739–749. doi:10.3233/JAD-2011-101875
    • (2011) J Alzheimers Dis , vol.24 , pp. 739-749
    • Zhang, X.1    Heng, X.2    Li, T.3    Li, L.4    Yang, D.5    Zhang, X.6    Du, Y.7    Doody, R.S.8    Le, W.9
  • 252
    • 1942468747 scopus 로고    scopus 로고
    • Prevention of MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) dopaminergic neurotoxicity in mice by chronic lithium: involvements of Bcl-2 and Bax
    • COI: 1:CAS:528:DC%2BD2cXjsVWgsLk%3D, PID: 15111020
    • Youdim MB, Arraf Z (2004) Prevention of MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) dopaminergic neurotoxicity in mice by chronic lithium: involvements of Bcl-2 and Bax. Neuropharmacology 46:1130–1140. doi:10.1016/j.neuropharm.2004.02.005
    • (2004) Neuropharmacology , vol.46 , pp. 1130-1140
    • Youdim, M.B.1    Arraf, Z.2
  • 253
    • 84922567318 scopus 로고    scopus 로고
    • Lithium prevents parkinsonian behavioral and striatal phenotypes in an aged parkin mutant transgenic mouse model
    • COI: 1:CAS:528:DC%2BC2cXhvVCktLfI, PID: 25452026
    • Lieu CA, Dewey CM, Chinta SJ, Rane A, Rajagopalan S, Batir S, Kim YH, Andersen JK (2014) Lithium prevents parkinsonian behavioral and striatal phenotypes in an aged parkin mutant transgenic mouse model. Brain Res 1591:111–117. doi:10.1016/j.brainres.2014.10.032
    • (2014) Brain Res , vol.1591 , pp. 111-117
    • Lieu, C.A.1    Dewey, C.M.2    Chinta, S.J.3    Rane, A.4    Rajagopalan, S.5    Batir, S.6    Kim, Y.H.7    Andersen, J.K.8
  • 254
    • 84940543768 scopus 로고    scopus 로고
    • The combination of lithium and l-Dopa/Carbidopa reduces MPTP-induced abnormal involuntary movements (AIMs) via calpain-1 inhibition in a mouse model: relevance for Parkinsons disease therapy
    • COI: 1:CAS:528:DC%2BC2MXhtFaitLrK, PID: 26119916
    • Lazzara CA, Riley RR, Rane A, Andersen JK, Kim YH (2015) The combination of lithium and l-Dopa/Carbidopa reduces MPTP-induced abnormal involuntary movements (AIMs) via calpain-1 inhibition in a mouse model: relevance for Parkinsons disease therapy. Brain Res 1622:127–136. doi:10.1016/j.brainres.2015.06.018
    • (2015) Brain Res , vol.1622 , pp. 127-136
    • Lazzara, C.A.1    Riley, R.R.2    Rane, A.3    Andersen, J.K.4    Kim, Y.H.5
  • 255
    • 84908569520 scopus 로고    scopus 로고
    • AQW051, a novel and selective nicotinic acetylcholine receptor alpha7 partial agonist, reduces l-Dopa-induced dyskinesias and extends the duration of l-Dopa effects in parkinsonian monkeys
    • PID: 25172125
    • Di Paolo T, Gregoire L, Feuerbach D, Elbast W, Weiss M, Gomez-Mancilla B (2014) AQW051, a novel and selective nicotinic acetylcholine receptor alpha7 partial agonist, reduces l-Dopa-induced dyskinesias and extends the duration of l-Dopa effects in parkinsonian monkeys. Parkinsonism Relat Disord 20:1119–1123. doi:10.1016/j.parkreldis.2014.05.007
    • (2014) Parkinsonism Relat Disord , vol.20 , pp. 1119-1123
    • Di Paolo, T.1    Gregoire, L.2    Feuerbach, D.3    Elbast, W.4    Weiss, M.5    Gomez-Mancilla, B.6
  • 256
    • 84907171021 scopus 로고    scopus 로고
    • The alpha7 nicotinic receptor agonist ABT-107 decreases l-Dopa-induced dyskinesias in parkinsonian monkeys
    • PID: 25034405, COI: 1:CAS:528:DC%2BC2cXhs1yksbbM
    • Zhang D, McGregor M, Decker MW, Quik M (2014) The alpha7 nicotinic receptor agonist ABT-107 decreases l-Dopa-induced dyskinesias in parkinsonian monkeys. J Pharmacol Exp Ther 351:25–32. doi:10.1124/jpet.114.216283
    • (2014) J Pharmacol Exp Ther , vol.351 , pp. 25-32
    • Zhang, D.1    McGregor, M.2    Decker, M.W.3    Quik, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.