The brain metabolite kynurenic acid inhibits α7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression: Physiopathological implications

Journal of Neuroscience

Volumn 21, Issue 19, 2001, Pages 7463-7473

  Hilmas, Corey ^a   Pereira, Edna F R ^a   Alkondon, Manickavasagom ^a   Rassoulpour, Arash ^a   Schwarcz, Robert ^a   Albuquerque, Edson X ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Brain slices; Electrophysiology; Hippocampus; Kynurenic acid; Nicotinic ACh receptors; NMDA receptors

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ACETYLCHOLINE; ATROPINE; CHOLINE; GLYCINE; KYNURENIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPROTECTIVE AGENT; NICOTINE; NICOTINIC RECEPTOR; PICROTOXIN; RECEPTOR SUBTYPE; TETRODOTOXIN;

ANIMAL CELL; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN PROTECTION; BRAIN SLICE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DRUG BINDING; FETUS; HIPPOCAMPUS; NERVE CELL CULTURE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0035478066     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-19-07463.2001     Document Type: Article

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