α7 and β2 nicotinic acetylcholine receptor subunits form heteromeric receptor complexes that are expressed in the human cortex and display distinct pharmacological properties

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Thomsen, Morten Skøtt ^a,d   Zwart, Ruud ^b   Ursu, Daniel ^b   Jensen, Majbrit Myrup ^a   Pinborg, Lars Hageman ^a   Gilmour, Gary ^b   Wu, Jie ^c   Sher, Emanuele ^b   Mikkelsen, Jens Damsgaard ^a  

^a University of Copenhagen   (Denmark)

^b ELI LILLY AND COMPANY   (United States)

^c BARROW NEUROLOGICAL INSTITUTE   (United States)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BUNGAROTOXIN RECEPTOR; CHOLINERGIC RECEPTOR BLOCKING AGENT; LIGAND; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BETA2; RECEPTOR SUBTYPE; NICOTINIC AGENT; NICOTINIC RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; BRAIN REGION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; FEMALE; HEK293 CELL LINE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; INTRACTABLE EPILEPSY; KINETICS; MALE; MOUSE; NONHUMAN; OOCYTE; TEMPORAL CORTEX; TEMPORAL LOBE EPILEPSY; VOLTAGE CLAMP TECHNIQUE; WESTERN BLOTTING; XENOPUS; ANIMAL; C57BL MOUSE; DEFICIENCY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; KNOCKOUT MOUSE; METABOLISM; PATCH CLAMP TECHNIQUE; PATHOLOGY; XENOPUS LAEVIS;

MUS; RODENTIA;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; CEREBRAL CORTEX; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; OOCYTES; PATCH-CLAMP TECHNIQUES; RECEPTORS, NICOTINIC; XENOPUS LAEVIS;

EID: 84939248743     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0130572     Document Type: Article

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