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Volumn 36, Issue 12, 2012, Pages 1552-1557

The nicotinic acetylcholine receptor a7 in subcutaneous mature adipocytes: Downregulation in human obesity and modulation by diet-induced weight loss

Author keywords

7nAChR; adipocytes; adipose tissue; chrna7; inflammation

Indexed keywords

4 CHLORO N (3 QUINUCLIDINYL)BENZAMIDE; GENISTEIN; MESSENGER RNA; NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

EID: 84870998884     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2011.275     Document Type: Article
Times cited : (54)

References (25)
  • 1
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development ofobesity-related insulin resistance
    • Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, et al. Chronic inflammation in fat plays a crucial role in the development ofobesity-related insulin resistance. J Clin Invest 2003; 112: 1821-1830.
    • (2003) J Clin Invest , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4    Yang, D.5    Chou, C.J.6
  • 3
    • 33748742519 scopus 로고    scopus 로고
    • Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue
    • Cancello R, Clement K. Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue. Br J Obstetr Gynaecol 2006; 113:1141-1147.
    • (2006) Br J Obstetr Gynaecol , vol.113 , pp. 1141-1147
    • Cancello, R.1    Clement, K.2
  • 5
    • 70349395711 scopus 로고    scopus 로고
    • Role of macrophage tissue infiltration in obesity and insulin resistance
    • Bourlier V, Bouloumie A. Role of macrophage tissue infiltration in obesity and insulin resistance. Diabetes Metab 2009; 35: 251-260.
    • (2009) Diabetes Metab , vol.35 , pp. 251-260
    • Bourlier, V.1    Bouloumie, A.2
  • 6
    • 70049110648 scopus 로고    scopus 로고
    • Inflammation, adipokines and obesity
    • Clement K, Vignes S. [Inflammation, adipokines and obesity]. Rev Med Interne 2009; 30: 824-832.
    • (2009) Rev Med Interne , vol.30 , pp. 824-832
    • Clement, K.1    Vignes, S.2
  • 7
    • 33846817498 scopus 로고    scopus 로고
    • Physiology and immunology of the cholinergic antiinflammatory pathway
    • Tracey KJ. Physiology and immunology of the cholinergic antiinflammatory pathway. J Clin Invest 2007; 117: 289-296.
    • (2007) J Clin Invest , vol.117 , pp. 289-296
    • Tracey, K.J.1
  • 8
    • 79953703686 scopus 로고    scopus 로고
    • Alpha7 nicotinic receptors as novel therapeutic targets for inflammation-based diseases
    • Bencherif M, Lippiello PM, Lucas R, Marrero MB. Alpha7 nicotinic receptors as novel therapeutic targets for inflammation-based diseases. Cell Mol Life Sci 2011; 68: 931-949.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 931-949
    • Bencherif, M.1    Lippiello, P.M.2    Lucas, R.3    Marrero, M.B.4
  • 9
    • 66149103723 scopus 로고    scopus 로고
    • Cholinergic control of inflammation
    • Rosas-Ballina M, Tracey KJ. Cholinergic control of inflammation. J Intern Med 2009; 265: 663-679.
    • (2009) J Intern Med , vol.265 , pp. 663-679
    • Rosas-Ballina, M.1    Tracey, K.J.2
  • 10
    • 0037461768 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation
    • Wang H, Yu M, Ochani M, Amella CA, Tanovic M, Susarla S, et al. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 2003; 421: 384-388.
    • (2003) Nature , vol.421 , pp. 384-388
    • Wang, H.1    Yu, M.2    Ochani, M.3    Amella, C.A.4    Tanovic, M.5    Susarla, S.6
  • 11
    • 79952487267 scopus 로고    scopus 로고
    • Application of alpha7 nicotinic acetylcholine receptor agonists in inflammatory diseases: An overview
    • Marrero MB, Bencherif M, Lippiello PM, Lucas R. Application of alpha7 nicotinic acetylcholine receptor agonists in inflammatory diseases: an overview. Pharm Res 2011; 28: 413-416.
    • (2011) Pharm Res , vol.28 , pp. 413-416
    • Marrero, M.B.1    Bencherif, M.2    Lippiello, P.M.3    Lucas, R.4
  • 13
    • 67349209574 scopus 로고    scopus 로고
    • A cog in cognition: How the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits
    • Leiser SC, Bowlby MR, Comery TA, Dunlop J. A cog in cognition: how the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits. Pharmacol Ther 2009; 122:302-311.
    • (2009) Pharmacol Ther , vol.122 , pp. 302-311
    • Leiser, S.C.1    Bowlby, M.R.2    Comery, T.A.3    Dunlop, J.4
  • 14
    • 73949111377 scopus 로고    scopus 로고
    • An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes
    • Marrero MB, Lucas R, Salet C, Hauser TA, Mazurov A, Lippiello PM, et al. An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes. J Pharmacol Exp Ther 2010; 332: 173-180.
    • (2010) J Pharmacol Exp Ther , vol.332 , pp. 173-180
    • Marrero, M.B.1    Lucas, R.2    Salet, C.3    Hauser, T.A.4    Mazurov, A.5    Lippiello, P.M.6
  • 15
    • 0035210724 scopus 로고    scopus 로고
    • Human bronchial epithelial and endothelial cells express alpha7 nicotinic acetylcholine receptors
    • Wang Y, Pereira EF, Maus AD, Ostlie NS, Navaneetham D, Lei S, et al. Human bronchial epithelial and endothelial cells express alpha7 nicotinic acetylcholine receptors. Mol Pharmacol 2001; 60: 1201-1209.
    • (2001) Mol Pharmacol , vol.60 , pp. 1201-1209
    • Wang, Y.1    Pereira, E.F.2    Maus, A.D.3    Ostlie, N.S.4    Navaneetham, D.5    Lei, S.6
  • 16
    • 33846470636 scopus 로고    scopus 로고
    • Chronic nicotine exposure enhances insulin-induced mitogenic signaling via up-regulation of alpha7 nicotinic receptors in isolated rat aortic smooth muscle cells
    • Wada T, Naito M, Kenmochi H, Tsuneki H, Sasaoka T. Chronic nicotine exposure enhances insulin-induced mitogenic signaling via up-regulation of alpha7 nicotinic receptors in isolated rat aortic smooth muscle cells. Endocrinology 2007; 148: 790-799.
    • (2007) Endocrinology , vol.148 , pp. 790-799
    • Wada, T.1    Naito, M.2    Kenmochi, H.3    Tsuneki, H.4    Sasaoka, T.5
  • 17
    • 17044426320 scopus 로고    scopus 로고
    • Rapid upregulation of alpha7 nicotinic acetylcholine receptors by tyrosine dephosphorylation
    • Cho CH, Song W, Leitzell K, Teo E, Meleth AD, Quick MW, et al. Rapid upregulation of alpha7 nicotinic acetylcholine receptors by tyrosine dephosphorylation. J Neurosci 2005; 25: 3712-3723.
    • (2005) J Neurosci , vol.25 , pp. 3712-3723
    • Cho, C.H.1    Song, W.2    Leitzell, K.3    Teo, E.4    Meleth, A.D.5    Quick, M.W.6
  • 18
    • 77953796760 scopus 로고    scopus 로고
    • Understanding immunity requires more than immunology
    • Tracey KJ. Understanding immunity requires more than immunology. Nat Immunol 2010; 11: 561-564.
    • (2010) Nat Immunol , vol.11 , pp. 561-564
    • Tracey, K.J.1
  • 19
    • 9844244026 scopus 로고    scopus 로고
    • Identification of nicotinic acetylcholine receptors on lymphocytes in the periphery as well as thymus in mice
    • Toyabe S, Iiai T, Fukuda M, Kawamura T, Suzuki S, Uchiyama M, et al. Identification of nicotinic acetylcholine receptors on lymphocytes in the periphery as well as thymus in mice. Immunology 1997; 92: 201-205.
    • (1997) Immunology , vol.92 , pp. 201-205
    • Toyabe, S.1    Iiai, T.2    Fukuda, M.3    Kawamura, T.4    Suzuki, S.5    Uchiyama, M.6
  • 20
    • 0037418233 scopus 로고    scopus 로고
    • Efferent vagal fibre stimulation blunts nuclear factor-kappaB activation and protects against hypovolemic hemorrhagic shock
    • Guarini S, Altavilla D, Cainazzo MM, Giuliani D, Bigiani A, Marini H, et al. Efferent vagal fibre stimulation blunts nuclear factor-kappaB activation and protects against hypovolemic hemorrhagic shock. Circulation 2003; 107: 1189-1194.
    • (2003) Circulation , vol.107 , pp. 1189-1194
    • Guarini, S.1    Altavilla, D.2    Cainazzo, M.M.3    Giuliani, D.4    Bigiani, A.5    Marini, H.6
  • 22
    • 33745830175 scopus 로고    scopus 로고
    • Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis
    • Huston JM, Ochani M, Rosas-Ballina M, Liao H, Ochani K, Pavlov VA, et al. Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis. J Exp Med 2006; 203: 1623-1628.
    • (2006) J Exp Med , vol.203 , pp. 1623-1628
    • Huston, J.M.1    Ochani, M.2    Rosas-Ballina, M.3    Liao, H.4    Ochani, K.5    Pavlov, V.A.6
  • 23
    • 3042548823 scopus 로고    scopus 로고
    • The expression and functional role of nicotinic acetylcholine receptors in rat adipocytes
    • Liu RH, Mizuta M, Matsukura S. The expression and functional role of nicotinic acetylcholine receptors in rat adipocytes. J Pharmacol Exp Ther 2004; 310: 52-58.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 52-58
    • Liu, R.H.1    Mizuta, M.2    Matsukura, S.3
  • 24
    • 79951875569 scopus 로고    scopus 로고
    • Activation of the cholinergic antiinflammatory pathway ameliorates obesity-induced inflammation and insulin resistance
    • Wang X, Yang Z, Xue B, Shi H. Activation of the cholinergic antiinflammatory pathway ameliorates obesity-induced inflammation and insulin resistance. Endocrinology 2011; 152: 836-846.
    • (2011) Endocrinology , vol.152 , pp. 836-846
    • Wang, X.1    Yang, Z.2    Xue, B.3    Shi, H.4
  • 25
    • 0347694718 scopus 로고    scopus 로고
    • Regulation of haptoglobin gene expression in 3T3-L1 adipocytes by cytokines, catecholamines and PPARγ
    • Do Nascimento CO, Hunter L, Trayhurn P. Regulation of haptoglobin gene expression in 3T3-L1 adipocytes by cytokines, catecholamines and PPARγ. Biochem Biophys Res Commun 2004; 313: 702-708.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 702-708
    • Do Nascimento, C.O.1    Hunter, L.2    Trayhurn, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.