Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway

Nature Immunology

Volumn 6, Issue 8, 2005, Pages 844-851

  de Jonge, Wouter J ^a   van der Zanden, Esmerij P ^a   The, Frans O ^a   Bijlsma, Maarten F ^a   van Westerloo, David J ^a   Bennink, Roelof J ^a   Berthoud, Hans Rudolf ^b   Uematsu, Satoshi ^c   Akira, Shizuo ^c   van den Wijngaard, Rene M ^a   Boeckxstaens, Guy E ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINERGIC RECEPTOR STIMULATING AGENT; JANUS KINASE 2; NICOTINE; NICOTINIC RECEPTOR; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; ACETYLCHOLINE; ALPHA-BUNGAROTOXIN RECEPTOR; ANTIINFLAMMATORY AGENT; BUNGAROTOXIN RECEPTOR; DNA BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; JAK2 PROTEIN, MOUSE; JAK2 PROTEIN, RAT; JAK3 PROTEIN, MOUSE; JAK3 PROTEIN, RAT; JANUS KINASE 3; ONCOPROTEIN; STAT3 PROTEIN, MOUSE; STAT3 PROTEIN, RAT; TRANSACTIVATOR PROTEIN;

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DRUG MECHANISM; FEMALE; GENE ACTIVATION; ILEUS; INFLAMMATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VAGUS NERVE; VAGUS NERVE STIMULATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; IMMUNOPRECIPITATION; INTESTINE; LEUKOCYTE; MACROPHAGE; MALE; METABOLISM; PATHOLOGY; PHAGOCYTE; PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TIME; TRANSACTIVATION;

ACETYLCHOLINE; ANIMALS; ANTI-INFLAMMATORY AGENTS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-6; INTESTINES; JANUS KINASE 2; JANUS KINASE 3; LEUKOCYTES; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NICOTINE; PHAGOCYTES; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSFECTION; VAGUS NERVE;

EID: 23844454674     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1229     Document Type: Article

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