α7 Nicotinic Receptor Transduces Signals to Phosphatidylinositol 3-Kinase to Block A β-Amyloid-induced Neurotoxicity

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 13541-13546

  Kihara, Takeshi ^a   Shimohama, Shun ^a   Sawada, Hideyuki ^a   Honda, Kazuhiro ^a   Nakamizo, Tomoki ^a   Shibasaki, Hiroshi ^a   Kume, Toshiaki ^a   Akaike, Akinori ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDEMIOLOGY; NEUROLOGY;

PATHOGEN;

BIOCHEMISTRY;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA BUNGAROTOXIN; AMYLOID BETA PROTEIN; BUNGAROTOXIN RECEPTOR; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; WORTMANNIN; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; AKT1 PROTEIN, RAT; ALPHA-BUNGAROTOXIN RECEPTOR; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA-PROTEIN (1-42); ANDROSTANE DERIVATIVE; BUNGAROTOXIN; CALCINEURIN; CHROMONE DERIVATIVE; ENZYME INHIBITOR; FYN PROTEIN, RAT; MORPHOLINE DERIVATIVE; NICOTINE; ONCOPROTEIN; PEPTIDE FRAGMENT; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN KINASE FYN; PROTEIN SERINE THREONINE KINASE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; FETUS; IMMUNOPRECIPITATION; NERVE CELL CULTURE; NEUROLOGIC DISEASE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; BRAIN CORTEX; CELL CULTURE; CELL DEATH; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOBLOTTING; METABOLISM; NERVE CELL; PHOSPHORYLATION; PRENATAL DEVELOPMENT; SERODIAGNOSIS; WESTERN BLOTTING;

ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMYLOID BETA-PROTEIN; ANDROSTADIENES; ANIMALS; BLOTTING, WESTERN; BUNGAROTOXINS; CALCINEURIN; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; CHROMONES; ENZYME INHIBITORS; GLUTAMIC ACID; IMMUNOBLOTTING; MODELS, BIOLOGICAL; MORPHOLINES; NEURONS; NICOTINE; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-FYN; RATS; RECEPTORS, NICOTINIC; SIGNAL TRANSDUCTION;

EID: 0035957946     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008035200     Document Type: Article

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