Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines

Molecular Pharmacology

Volumn 64, Issue 4, 2003, Pages 885-889

  Skok, Marina V ^a   Kalashnik, Elena N ^a   Koval, Ludmila N ^a   Tsetlin, Victor I ^b   Utkin, Yuriy N ^b   Changeux, Jean Pierre ^c   Grailhe, Régis ^c  

^a PALLADIN INSTITUTE OF BIOCHEMISTRY   (Ukraine)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BUNGAROTOXIN; BUNGAROTOXIN RECEPTOR; CHOLINERGIC RECEPTOR; EPIBATIDINE; NICOTINE; NICOTINIC ALPHA4 RECEPTOR; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT; SNAKE VENOM; UNCLASSIFIED DRUG;

ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ARTICLE; B LYMPHOCYTE; BINDING SITE; CELL FUNCTION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; HUMAN; HUMAN CELL; HYBRIDOMA CELL CULTURE; IMMUNE RESPONSE; LONG TERM EXPOSURE; MYELOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SMOKING; STATISTICAL SIGNIFICANCE;

ANIMALS; B-LYMPHOCYTES; CELL DIVISION; MICE; RECEPTORS, NICOTINIC; TUMOR CELLS, CULTURED;

EID: 0141569322     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.4.885     Document Type: Article

References (36)

1. Alberts B, Bray D, Lewis J, Raff M, Roberts K, and Watson JD (1989) Molecular Biology of the Cell, 2nd ed, Garland Publishing, Inc., New York.
2. Andersen P, Pedersen OF, Bach B, and Bonde GJ (1982) Serum antibodies and immunoglobulins in smokers and nonsmokers. Clin Exp Immunol 47:467-473.
3. Battaglioli E, Gotti C, Terzano S, Flora A, Clementi F, and Fornasari D (1998) Expression and transcriptional regulation of the human alpha3 neuronal nicotinic receptor subunit in T lymphocyte cell lines. J Neurochem 71:1261-1270.
4. Benhammou K, Lee M, Strook M, Sullivan B, Logel J, Raschen K, Gotti C, and Leonard S (2000) [(3)H]Nicotine binding in peripheral blood cells of smokers is correlated with the number of cigarettes smoked per day. Neuropharmacology 39:2818-2829.
5. Carmichael J, DeGraff WG, Gazdar AF, Minna JD, and Mitchell JB (1987) Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity. Cancer Res 47:943-946.
6. Changeux JP, Bertrand D, Corringer PJ, Dehaene S, Edelstein S, Lena C, Le Novère N, Marubio L, Picciotto M, and Zoli M (1998) Brain nicotinic receptors: structure and regulation, role in learning and reinforcement. Brain Res Brain Res Rev 26:198-216.
7. Chini B, Clementi F, Hukovic N, and Sher E (1992) Neuronal-type α-bungarotoxin receptors and the α5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines. Proc Natl Acad Sci USA 89:1572-1576.
8. Codignola A, Tarroni P, Cattaneo MG, Vicentini LM, Clementi F, and Sher E (1994) Serotonin release and cell proliferation are under the control of alpha-bungarotoxin-sensitive nicotinic receptors in small-cell lung carcinoma cell lines. FEBS Lett 342:286-290.
9. Grando SA (1997) Biological functions of keratinocyte cholinergic receptors. J Investig Dermatol Symp Proc 2:41-48.
10. Harlow E and Lane D (1988) Antibodies. A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
11. Hughes DA, Haslam PL, Townsend PJ, and Turner-Warwick M (1985) Numerical and functional alterations in circulatory lymphocytes in cigarette smokers. Clin Exp Immunol 61:459-466.
12. Kawai H and Berg DK (2001) Nicotinic acetylcholine receptors containing A7 subunits on rat cortical neurons do not undergo long-lasting inactivation even when up-regulated by chronic nicotine exposure. J Neurochem 78:1367-1378.
13. Lindstrom J, Schoepfer R, and Whiting P (1987) Molecular studies of the neuronal nicotinic acetylcholine receptor family. Mol Neurobiol 1:281-337.
14. Loembe MM, Lamoureux J, Deslauriers N, Darveau A, and Delage R (2001) Lack of CD40-dependent B-cell proliferation in B lymphocytes isolated from patients with persistent polyclonal B-cell lymphocytosis. Br J Haematol 113:699-705.
15. Lustig LR, Peng H, Hiel H, Yamamoto T, and Fuchs PA (2001) Molecular cloning and mapping of the human nicotinic acetylcholine receptor alpha10 (CHRNA10). Genomics 73:272-283.
16. Macklin KD, Maus AD, Pereira EF, Albuquerque EX, and Conti-Fine BM (1998) Human vascular endothelial cells express functional nicotinic acetylcholine receptors. J Pharmacol Exp Ther 287:435-439.
17. Marks MJ, Pauly JR, Gross SD, Deneris ES, Hermans-Borgmeyer I, Heinemann SF, and Collins AC (1992) Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment. J Neurosci 9:2765-2784.
18. Maslinski W, Laskowska-Bozek H, and Ryzewski J (1992) Nicotinic receptors of rat lymphocytes during adjuvant polyarthritis. J Neurosci Res 31:336-340.
19. Maus AD, Pereira EF, Karachunski PI, Horton RM, Navaneetham D, Maclkin K, Cortes WS, Albuquerque EX, and Conti-Fine BM (1998) Human and rodent bronchial epithelial cells express functional nicotinic acetylcholine receptors. Mol Pharmacol 54:779-788.
20. Nguyen VT, Hall LL, Gallacher G, Ndoye A, Jolkovsky DL, Webber RJ, Buchli R, and Grande SA (2000) Choline acetyltransferase, acetylcholinesterase and nicotinic acetylcholine receptors of human gingival and esophageal epithelia. J Dent Res 79:939-949.
21. Peng X, Gerzaniich V, Anand R, and Wang F (1997) Chronic nicotine treatment up-regulates 3 and 7 acetylcholine receptor subtypes expressed by the human neuroblastoma cell line SH-SY5Y. Mol Pharmacol 51:776-784.
22. Quik M, Chan J, and Patrick J (1994) alpha-Bungarotoxin blocks the nicotinic receptor mediated increase in cell number in a neuroendocrine cell line. Brain Res 655:161-167.
23. Rinner I, Kawashima K, and Schauenstein K (1998) Rat lymphocytes produce and secrete acetylcholine in dependence of differentiation and activation. J Neuroimmunol 81:31-37.
24. Sato KZ, Fujii T, Watanabe Y, Yamada S, Ando T, Kazuko F, and Kawashima K (1999) Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines. Neurosci Lett 266:17-20.
25. Savage SM, Donaldson LA, Cherian S, Chilukuri R, White VA, and Sopori ML (1991) Effects of cigarette smoke on the immune response. II. Chronic exposure to cigarette smoke inhibits surface immunoglobulin-mediated responses in B cells. Toxicol App Pharmacol 111:523-529.
26. Sciamanna MA, Griesmann GE, Williams CL, and Lennon VA (1997) Nicotinic acetylcholine receptors of muscle and neuronal (alpha7) types coexpressed in a small cell lung carcinoma. J Neurochem 69:2302-2311.
27. 3H]epibatidine binding in relation to vesicular acetylcholine transport sites in the temporal cortex in Alzheimer's disease. Neuroscience 94:685-696.
28. Skok M, Lykhmus E, Bobrovnik S, Tzartos S, Tsouloufis T, Vanderesse R, Coutrot F, Thong Cung M, Marraud M, Krikorian D, et al. (2001) Structure of epitopes recognized by the antibodies to alpha(181-192) peptides of neuronal nicotinic acetylcholine receptors: extrapolation to the structure of acetylcholine-binding domain. J Neuroimmunol 121:59-66.
29. Skok MV, Voitenko LP, Voitenko SV, Lykhmus EY, Kalashnik EN, Litvin TI, Tzartos SJ, and Skok VI (1999) Alpha subunit composition of nicotinic acetylcholine receptors in the rat autonomic ganglia neurons as determined with subunit-specific anti-alpha(181-192) peptide antibodies. Neuroscience 93:1427-1436.
30. Sopori ML, Kozak W, Savage SM, Geng Y, and Kluger MJ (1998a) Nicotine-induced modulation of T Cell function. Implications for inflammation and infection. Adv Exp Med Biol 437:279-289.
31. Sopori ML, Kozak W, Savage SM, Geng Y, Soszynski D, Kluger MJ, Perryman EK, and Snow GE (1998b) Effect of nicotine on the immune system: possible regulation of immune responses by central and peripheral mechanisms. Psychoneuroendocrinology 23:189-204.
32. Tsetlin V (1999) Snake venom alpha-neurotoxins and other 'three-finger' proteins. Eur J Biochem 264:281-286.
33. Utkin YN, Kukhtina VV, Kryukova EV, Chiodini F, Bertrand D, Methfessel C, and Tsetlin VI (2001) "Weak toxin" from Naja kaouthia is a nontoxic antagonist of α7 and muscle-type nicotinic acetylcholine receptors. J Biol Chem 276:15810-15815.
34. Voitenko LP, Voitenko SV, Skok MV, Purnyn HE, and Skok VI (2001) Nicotinic acetylcholine receptor subtypes in rat superior cervical ganglion neurons as studied by sequential application of two alpha-subunit-specific antibodies. Neurosci Lett 303:37-40.
35. Vulfius CA, Krasts IV, Utkin YN, and Tsetlin VI (2001) Nicotinic receptors in Lymnaea stagnalis neurons are blocked by alpha-neurotoxins from cobra venoms. Neurosci Lett 309:189-192.
36. Yates SL, Bencherif M, Fluhler EN, and Lippiello PM (1995) Up-regulation of nicotinic acetylcholine receptors following chronic exposure of rats to mainstream cigarette smoke or alpha 4 beta 2 receptors to nicotine. Biochem Pharmacol 50:2001-2008.