A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via α7 nicotinic receptors in human macrophages

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Maldifassi, Maria C ^a   Atienza, Gema ^a   Arnalich, Francisco ^b   López Collazo, Eduardo ^b   Cedillo, Jose L ^a   Martín Sánchez, Carolina ^a   Bordas, Anna ^a   Renart, Jaime ^c   Montiel, Carmen ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^c CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BUNGAROTOXIN RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; JANUS KINASE 2; MESSENGER RNA; NICOTINE; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK3 PROTEIN, HUMAN; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; INNATE IMMUNITY; IRAK M GENE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; CELL CULTURE; DRUG EFFECTS; METABOLISM;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; DOWN-REGULATION; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LIPOPOLYSACCHARIDES; MACROPHAGES; NICOTINE; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84907916535     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108397     Document Type: Article

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