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Volumn 228, Issue 3, 2015, Pages 945-949

Genes involved in pruning and inflammation are enriched in a large mega-sample of patients affected by Schizophrenia and Bipolar Disorder and controls

Author keywords

Pathway analysis; Pruning; Schizophrenia

Indexed keywords

ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; GENE; GENETIC ANALYSIS; HLA C GENE; HLA DRA GENE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; SYNAPTIC PRUNING; SYNAPTIC TRANSMISSION; ADULT; FEMALE; GENE REGULATORY NETWORK; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; INTERNATIONAL COOPERATION; MALE; MIDDLE AGED; NERVE CELL PLASTICITY;

EID: 84938746414     PISSN: 01651781     EISSN: 18727123     Source Type: Journal    
DOI: 10.1016/j.psychres.2015.06.013     Document Type: Article
Times cited : (24)

References (53)
  • 1
    • 0032737272 scopus 로고    scopus 로고
    • Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain
    • Alliot F., Godin I., Pessac B. Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain. Brain Res. Dev. Brain Res. 1999, 117(2):145-152.
    • (1999) Brain Res. Dev. Brain Res. , vol.117 , Issue.2 , pp. 145-152
    • Alliot, F.1    Godin, I.2    Pessac, B.3
  • 2
    • 0027321416 scopus 로고
    • Autoimmunity and schizophrenia: an epiphenomenon or an etiology?
    • Amital H., Shoenfeld Y. Autoimmunity and schizophrenia: an epiphenomenon or an etiology?. Isr. J. Med. Sci. 1993, 29(9):593-597.
    • (1993) Isr. J. Med. Sci. , vol.29 , Issue.9 , pp. 593-597
    • Amital, H.1    Shoenfeld, Y.2
  • 3
    • 0019945874 scopus 로고
    • Impairment of the blood-brain barrier as an aetiological factor in paranoid psychosis
    • Axelsson R., Martensson E., Alling C. Impairment of the blood-brain barrier as an aetiological factor in paranoid psychosis. Br. J. Psychiatry 1982, 141:273-281.
    • (1982) Br. J. Psychiatry , vol.141 , pp. 273-281
    • Axelsson, R.1    Martensson, E.2    Alling, C.3
  • 4
    • 84938751682 scopus 로고    scopus 로고
    • Psychiatric Emergencies, The Merck Manual of Diagnosis and Therapy
    • Merck Research Laboratories, Whitehouse Station, NJ
    • Beers M.H., Berkow R. Psychiatric Emergencies, The Merck Manual of Diagnosis and Therapy 2004, Merck Research Laboratories, Whitehouse Station, NJ.
    • (2004)
    • Beers, M.H.1    Berkow, R.2
  • 5
    • 73149103718 scopus 로고    scopus 로고
    • Prioritizing GWAS results: a review of statistical methods and recommendations for their application
    • Cantor R.M., Lange K., Sinsheimer J.S. Prioritizing GWAS results: a review of statistical methods and recommendations for their application. Am. J. Hum. Genet. 2010, 86(1):6-22.
    • (2010) Am. J. Hum. Genet. , vol.86 , Issue.1 , pp. 6-22
    • Cantor, R.M.1    Lange, K.2    Sinsheimer, J.S.3
  • 6
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
    • Cross-Disorder Group of the Psychiatric Genomics C. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 2013, 381(9875):1371-1379.
    • (2013) Lancet , vol.381 , Issue.9875 , pp. 1371-1379
  • 7
    • 84873525772 scopus 로고    scopus 로고
    • Variation in the major histocompatibility complex [MHC] gene family in schizophrenia: associations and functional implications
    • Debnath M., Cannon D.M., Venkatasubramanian G. Variation in the major histocompatibility complex [MHC] gene family in schizophrenia: associations and functional implications. Prog. Neuropsychopharmacol. Biol. Psychiatry 2013, 42:49-62.
    • (2013) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.42 , pp. 49-62
    • Debnath, M.1    Cannon, D.M.2    Venkatasubramanian, G.3
  • 8
    • 84900521403 scopus 로고    scopus 로고
    • Genome-wide association study supports the role of the immunological system and of the neurodevelopmental processes in response to haloperidol treatment
    • Drago A., Giegling I., Schafer M., Hartmann A.M., Konte B., Friedl M., Serretti A., Rujescu D. Genome-wide association study supports the role of the immunological system and of the neurodevelopmental processes in response to haloperidol treatment. Pharmacogenet. Genomics 2014, 24(6):314-319.
    • (2014) Pharmacogenet. Genomics , vol.24 , Issue.6 , pp. 314-319
    • Drago, A.1    Giegling, I.2    Schafer, M.3    Hartmann, A.M.4    Konte, B.5    Friedl, M.6    Serretti, A.7    Rujescu, D.8
  • 9
    • 77952423873 scopus 로고    scopus 로고
    • Contributions of astrocytes to synapse formation and maturation-Potential functions of the perisynaptic extracellular matrix
    • Faissner A., Pyka M., Geissler M., Sobik T., Frischknecht R., Gundelfinger E.D., Seidenbecher C. Contributions of astrocytes to synapse formation and maturation-Potential functions of the perisynaptic extracellular matrix. Brain Res. Rev. 2010, 63(1-2):26-38.
    • (2010) Brain Res. Rev. , vol.63 , Issue.1-2 , pp. 26-38
    • Faissner, A.1    Pyka, M.2    Geissler, M.3    Sobik, T.4    Frischknecht, R.5    Gundelfinger, E.D.6    Seidenbecher, C.7
  • 10
    • 78650666785 scopus 로고    scopus 로고
    • Role of immune molecules in the establishment and plasticity of glutamatergic synapses
    • Fourgeaud L., Boulanger L.M. Role of immune molecules in the establishment and plasticity of glutamatergic synapses. Eur. J. Neurosci. 2010, 32(2):207-217.
    • (2010) Eur. J. Neurosci. , vol.32 , Issue.2 , pp. 207-217
    • Fourgeaud, L.1    Boulanger, L.M.2
  • 12
    • 84863527564 scopus 로고    scopus 로고
    • Genome-wide association studies in schizophrenia, and potential etiological and functional implications of their results
    • Hosak L., Silhan P., Hosakova J. Genome-wide association studies in schizophrenia, and potential etiological and functional implications of their results. Acta Med. (Hradec Kralove) 2012, 55(1):3-11.
    • (2012) Acta Med. (Hradec Kralove) , vol.55 , Issue.1 , pp. 3-11
    • Hosak, L.1    Silhan, P.2    Hosakova, J.3
  • 13
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie B.N., Donnelly P., Marchini J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 2009, 5(6):e1000529.
    • (2009) PLoS Genet. , vol.5 , Issue.6
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 14
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia C., Purcell S.M., Wray N.R., Stone J.L., Visscher P.M., O'Donovan M.C., Sullivan P.F., Sklar P. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009, 460(7256):748-752.
    • (2009) Nature , vol.460 , Issue.7256 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5    Sullivan, P.F.6    Sklar, P.7
  • 16
    • 79960051705 scopus 로고    scopus 로고
    • [Psycho-immunological mechanisms in schizophrenia]
    • Karanikas E.P. [Psycho-immunological mechanisms in schizophrenia]. Psychiatriki 2011, 22(1):43-52.
    • (2011) Psychiatriki , vol.22 , Issue.1 , pp. 43-52
    • Karanikas, E.P.1
  • 18
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: a sensor for pathological events in the CNS
    • Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 1996, 19(8):312-318.
    • (1996) Trends Neurosci. , vol.19 , Issue.8 , pp. 312-318
    • Kreutzberg, G.W.1
  • 19
    • 77956903409 scopus 로고    scopus 로고
    • Common variants in major histocompatibility complex region and TCF4 gene are significantly associated with schizophrenia in Han Chinese
    • Li T., Li Z., Chen P., Zhao Q., Wang T., Huang K., Li J., Li Y., Liu J., Zeng Z., Feng G., He L., Shi Y. Common variants in major histocompatibility complex region and TCF4 gene are significantly associated with schizophrenia in Han Chinese. Biol. Psychiatry 2010, 68(7):671-673.
    • (2010) Biol. Psychiatry , vol.68 , Issue.7 , pp. 671-673
    • Li, T.1    Li, Z.2    Chen, P.3    Zhao, Q.4    Wang, T.5    Huang, K.6    Li, J.7    Li, Y.8    Liu, J.9    Zeng, Z.10    Feng, G.11    He, L.12    Shi, Y.13
  • 20
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • Marchini J., Howie B., Myers S., McVean G., Donnelly P. A new multipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet. 2007, 39(7):906-913.
    • (2007) Nat. Genet. , vol.39 , Issue.7 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5
  • 21
    • 0034432163 scopus 로고    scopus 로고
    • Familial multiple sclerosis with repetitive relapses of manic psychosis in two patients (mother and daughter)
    • Modrego P.J., Ferrandez J. Familial multiple sclerosis with repetitive relapses of manic psychosis in two patients (mother and daughter). Behav. Neurol. 2000, 12(4):175-179.
    • (2000) Behav. Neurol. , vol.12 , Issue.4 , pp. 175-179
    • Modrego, P.J.1    Ferrandez, J.2
  • 23
    • 0342439882 scopus 로고    scopus 로고
    • Increase in expression of adhesion molecule receptors on T helper cells during antipsychotic treatment and relationship to blood-brain barrier permeability in schizophrenia
    • Muller N., Riedel M., Hadjamu M., Schwarz M.J., Ackenheil M., Gruber R. Increase in expression of adhesion molecule receptors on T helper cells during antipsychotic treatment and relationship to blood-brain barrier permeability in schizophrenia. Am. J. Psychiatry 1999, 156(4):634-636.
    • (1999) Am. J. Psychiatry , vol.156 , Issue.4 , pp. 634-636
    • Muller, N.1    Riedel, M.2    Hadjamu, M.3    Schwarz, M.J.4    Ackenheil, M.5    Gruber, R.6
  • 24
    • 79956199179 scopus 로고    scopus 로고
    • Schizophrenia risk genes: Implications for future drug development and discovery
    • O'Connell G., Lawrie S.M., McIntosh A.M., Hall J. Schizophrenia risk genes: Implications for future drug development and discovery. Biochem. Pharmacol. 2011, 81(12):1367-1373.
    • (2011) Biochem. Pharmacol. , vol.81 , Issue.12 , pp. 1367-1373
    • O'Connell, G.1    Lawrie, S.M.2    McIntosh, A.M.3    Hall, J.4
  • 25
    • 0036949032 scopus 로고    scopus 로고
    • Regulation and function of class II major histocompatibility complex, CD40, and B7 expression in macrophages and microglia: Implications in neurological diseases
    • O'Keefe G.M., Nguyen V.T., Benveniste E.N. Regulation and function of class II major histocompatibility complex, CD40, and B7 expression in macrophages and microglia: Implications in neurological diseases. J. Neurovirol. 2002, 8(6):496-512.
    • (2002) J. Neurovirol. , vol.8 , Issue.6 , pp. 496-512
    • O'Keefe, G.M.1    Nguyen, V.T.2    Benveniste, E.N.3
  • 26
    • 56549127348 scopus 로고    scopus 로고
    • Why do many psychiatric disorders emerge during adolescence?
    • Paus T., Keshavan M., Giedd J.N. Why do many psychiatric disorders emerge during adolescence?. Nat. Rev. Neurosci. 2008, 9(12):947-957.
    • (2008) Nat. Rev. Neurosci. , vol.9 , Issue.12 , pp. 947-957
    • Paus, T.1    Keshavan, M.2    Giedd, J.N.3
  • 27
    • 78149276744 scopus 로고    scopus 로고
    • Permutation P-values should never be zero: calculating exact P-values when permutations are randomly drawn
    • Phipson B., Smyth G.K. Permutation P-values should never be zero: calculating exact P-values when permutations are randomly drawn. Stat. Appl. Genet. Mol. Biol. 2010, 9. Article39.
    • (2010) Stat. Appl. Genet. Mol. Biol. , vol.9
    • Phipson, B.1    Smyth, G.K.2
  • 30
    • 84914179053 scopus 로고    scopus 로고
    • R: A Language and Environment for Statistical Computing
    • R Core Team, 2014. R: A Language and Environment for Statistical Computing.
    • (2014)
  • 31
    • 0035671763 scopus 로고    scopus 로고
    • Review of immunological and immunopathological findings in schizophrenia
    • Rothermundt M., Arolt V., Bayer T.A. Review of immunological and immunopathological findings in schizophrenia. Brain. Behav. Immunol. 2001, 15(4):319-339.
    • (2001) Brain. Behav. Immunol. , vol.15 , Issue.4 , pp. 319-339
    • Rothermundt, M.1    Arolt, V.2    Bayer, T.A.3
  • 33
    • 0019481002 scopus 로고
    • Myelin basic protein antibodies in the serum and CSF of multiple sclerosis and subacute sclerosing panencephalitis patients
    • Ruutiainen J., Arnadottir T., Molnar G., Salmi A., Frey H. Myelin basic protein antibodies in the serum and CSF of multiple sclerosis and subacute sclerosing panencephalitis patients. Acta Neurol. Scand. 1981, 64(3):196-206.
    • (1981) Acta Neurol. Scand. , vol.64 , Issue.3 , pp. 196-206
    • Ruutiainen, J.1    Arnadottir, T.2    Molnar, G.3    Salmi, A.4    Frey, H.5
  • 36
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • Schizophrenia Psychiatric Genome-Wide Association Study C. Genome-wide association study identifies five new schizophrenia loci. Nat. Genet. 2011, 43(10):969-976.
    • (2011) Nat. Genet. , vol.43 , Issue.10 , pp. 969-976
  • 37
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • Schizophrenia Working Group of the Psychiatric Genomics C. Biological insights from 108 schizophrenia-associated genetic loci. Nature 2014, 511(7510):421-427.
    • (2014) Nature , vol.511 , Issue.7510 , pp. 421-427
  • 39
    • 0034653179 scopus 로고    scopus 로고
    • Decreased levels of soluble intercellular adhesion molecule-1 (sICAM-1) in unmedicated and medicated schizophrenic patients
    • Schwarz M.J., Riedel M., Ackenheil M., Muller N. Decreased levels of soluble intercellular adhesion molecule-1 (sICAM-1) in unmedicated and medicated schizophrenic patients. Biol. Psychiatry 2000, 47(1):29-33.
    • (2000) Biol. Psychiatry , vol.47 , Issue.1 , pp. 29-33
    • Schwarz, M.J.1    Riedel, M.2    Ackenheil, M.3    Muller, N.4
  • 40
    • 81955161247 scopus 로고    scopus 로고
    • The first decade and beyond of transcriptional profiling in schizophrenia
    • Sequeira P.A., Martin M.V., Vawter M.P. The first decade and beyond of transcriptional profiling in schizophrenia. Neurobiol. Dis. 2012, 45(1):23-36.
    • (2012) Neurobiol. Dis. , vol.45 , Issue.1 , pp. 23-36
    • Sequeira, P.A.1    Martin, M.V.2    Vawter, M.P.3
  • 41
    • 45449091369 scopus 로고    scopus 로고
    • Shared gene expression alterations in schizophrenia and bipolar disorder
    • Shao L., Vawter M.P. Shared gene expression alterations in schizophrenia and bipolar disorder. Biol. Psychiatry 2008, 64(2):89-97.
    • (2008) Biol. Psychiatry , vol.64 , Issue.2 , pp. 89-97
    • Shao, L.1    Vawter, M.P.2
  • 44
    • 84860338445 scopus 로고    scopus 로고
    • The complement system: an unexpected role in synaptic pruning during development and disease
    • Stephan A.H., Barres B.A., Stevens B. The complement system: an unexpected role in synaptic pruning during development and disease. Annu. Rev. Neurosci. 2012, 35:369-389.
    • (2012) Annu. Rev. Neurosci. , vol.35 , pp. 369-389
    • Stephan, A.H.1    Barres, B.A.2    Stevens, B.3
  • 46
    • 33749531529 scopus 로고    scopus 로고
    • Schizophrenia, autoimmunity and immune system dysregulation: a comprehensive model updated and revisited
    • Strous R.D., Shoenfeld Y. Schizophrenia, autoimmunity and immune system dysregulation: a comprehensive model updated and revisited. J. Autoimmun. 2006, 27(2):71-80.
    • (2006) J. Autoimmun. , vol.27 , Issue.2 , pp. 71-80
    • Strous, R.D.1    Shoenfeld, Y.2
  • 47
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies
    • Sullivan P.F., Kendler K.S., Neale M.C. Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch. Gen. Psychiatry 2003, 60(12):1187-1192.
    • (2003) Arch. Gen. Psychiatry , vol.60 , Issue.12 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 48
    • 84863088484 scopus 로고    scopus 로고
    • Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases
    • Tian L., Ma L., Kaarela T., Li Z. Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases. J. Neuroinflamm. 2012, 9:155.
    • (2012) J. Neuroinflamm. , vol.9 , pp. 155
    • Tian, L.1    Ma, L.2    Kaarela, T.3    Li, Z.4
  • 51
    • 22144498857 scopus 로고    scopus 로고
    • Quantitative analysis of activated microglia, ramified and damage of processes in the frontal and temporal lobes of chronic schizophrenics
    • Wierzba-Bobrowicz T., Lewandowska E., Lechowicz W., Stepien T., Pasennik E. Quantitative analysis of activated microglia, ramified and damage of processes in the frontal and temporal lobes of chronic schizophrenics. Folia Neuropathol. 2005, 43(2):81-89.
    • (2005) Folia Neuropathol. , vol.43 , Issue.2 , pp. 81-89
    • Wierzba-Bobrowicz, T.1    Lewandowska, E.2    Lechowicz, W.3    Stepien, T.4    Pasennik, E.5


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