메뉴 건너뛰기




Volumn 172, Issue 23, 2015, Pages 5457-5476

The interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseases

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 2; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 4; INTERFERON REGULATORY FACTOR 5; INTERFERON REGULATORY FACTOR 7; INTERFERON REGULATORY FACTOR 9; PATTERN RECOGNITION RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

EID: 84949529544     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12881     Document Type: Review
Times cited : (34)

References (227)
  • 1
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O, (2006). Pathogen recognition and innate immunity. Cell 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 2
    • 0037712882 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 immunoreactivity in neurons and inflammatory cells following ischemic stroke in rodents and humans
    • Alexander M, Forster C, Sugimoto K, Clark HB, Vogel S, Ross ME, et al. (2003). Interferon regulatory factor-1 immunoreactivity in neurons and inflammatory cells following ischemic stroke in rodents and humans. Acta Neuropathol 105: 420-424.
    • (2003) Acta Neuropathol , vol.105 , pp. 420-424
    • Alexander, M.1    Forster, C.2    Sugimoto, K.3    Clark, H.B.4    Vogel, S.5    Ross, M.E.6
  • 3
    • 84857293493 scopus 로고    scopus 로고
    • Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease
    • Alexander MR, Owens GK, (2012). Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease. Annu Rev Physiol 74: 13-40.
    • (2012) Annu Rev Physiol , vol.74 , pp. 13-40
    • Alexander, M.R.1    Owens, G.K.2
  • 7
    • 57349121051 scopus 로고    scopus 로고
    • Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination
    • Balkhi MY, Fitzgerald KA, Pitha PM, (2008). Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination. Mol Cell Biol 28: 7296-7308.
    • (2008) Mol Cell Biol , vol.28 , pp. 7296-7308
    • Balkhi, M.Y.1    Fitzgerald, K.A.2    Pitha, P.M.3
  • 8
    • 33748447541 scopus 로고    scopus 로고
    • Type i interferon in systemic lupus erythematosus and other autoimmune diseases
    • Banchereau J, Pascual V, (2006). Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 25: 383-392.
    • (2006) Immunity , vol.25 , pp. 383-392
    • Banchereau, J.1    Pascual, V.2
  • 9
    • 15244359631 scopus 로고    scopus 로고
    • Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3
    • Barro M, Patton JT, (2005). Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3. Proc Natl Acad Sci U S A 102: 4114-4119.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 4114-4119
    • Barro, M.1    Patton, J.T.2
  • 10
    • 33947382185 scopus 로고    scopus 로고
    • Classical swine fever virus Npro interacts with interferon regulatory factor 3 and induces its proteasomal degradation
    • Bauhofer O, Summerfield A, Sakoda Y, Tratschin JD, Hofmann MA, Ruggli N, (2007). Classical swine fever virus Npro interacts with interferon regulatory factor 3 and induces its proteasomal degradation. J Virol 81: 3087-3096.
    • (2007) J Virol , vol.81 , pp. 3087-3096
    • Bauhofer, O.1    Summerfield, A.2    Sakoda, Y.3    Tratschin, J.D.4    Hofmann, M.A.5    Ruggli, N.6
  • 11
    • 84857724877 scopus 로고    scopus 로고
    • IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors
    • Becker AM, Michael DG, Satpathy AT, Sciammas R, Singh H, Bhattacharya D, (2012). IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors. Blood 119: 2003-2012.
    • (2012) Blood , vol.119 , pp. 2003-2012
    • Becker, A.M.1    Michael, D.G.2    Satpathy, A.T.3    Sciammas, R.4    Singh, H.5    Bhattacharya, D.6
  • 12
    • 0036144763 scopus 로고    scopus 로고
    • Regulatory functions of ubiquitination in the immune system
    • Ben-Neriah Y, (2002). Regulatory functions of ubiquitination in the immune system. Nat Immunol 3: 20-26.
    • (2002) Nat Immunol , vol.3 , pp. 20-26
    • Ben-Neriah, Y.1
  • 13
    • 84873868258 scopus 로고    scopus 로고
    • Signaling effectors underlying pathologic growth and remodeling of the heart
    • van Berlo JH, Maillet M, Molkentin JD, (2013). Signaling effectors underlying pathologic growth and remodeling of the heart. J Clin Invest 123: 37-45.
    • (2013) J Clin Invest , vol.123 , pp. 37-45
    • Van Berlo, J.H.1    Maillet, M.2    Molkentin, J.D.3
  • 15
    • 79954577277 scopus 로고    scopus 로고
    • TLR-signaling networks: An integration of adaptor molecules, kinases, and cross-talk
    • Brown J, Wang H, Hajishengallis GN, Martin M, (2011). TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. J Dent Res 90: 417-427.
    • (2011) J Dent Res , vol.90 , pp. 417-427
    • Brown, J.1    Wang, H.2    Hajishengallis, G.N.3    Martin, M.4
  • 16
    • 0347298773 scopus 로고    scopus 로고
    • Acetylation of interferon regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA binding
    • Caillaud A, Prakash A, Smith E, Masumi A, Hovanessian AG, Levy DE, et al. (2002). Acetylation of interferon regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA binding. J Biol Chem 277: 49417-49421.
    • (2002) J Biol Chem , vol.277 , pp. 49417-49421
    • Caillaud, A.1    Prakash, A.2    Smith, E.3    Masumi, A.4    Hovanessian, A.G.5    Levy, D.E.6
  • 18
    • 68249115320 scopus 로고    scopus 로고
    • Injury and repair mechanisms in ischemic stroke: Considerations for the development of novel neurotherapeutics
    • Candelario-Jalil E, (2009). Injury and repair mechanisms in ischemic stroke: considerations for the development of novel neurotherapeutics. Curr Opin Investig Drugs 10: 644-654.
    • (2009) Curr Opin Investig Drugs , vol.10 , pp. 644-654
    • Candelario-Jalil, E.1
  • 19
    • 34247545017 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke
    • Caso JR, Pradillo JM, Hurtado O, Lorenzo P, Moro MA, Lizasoain I, (2007). Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. Circulation 115: 1599-1608.
    • (2007) Circulation , vol.115 , pp. 1599-1608
    • Caso, J.R.1    Pradillo, J.M.2    Hurtado, O.3    Lorenzo, P.4    Moro, M.A.5    Lizasoain, I.6
  • 21
    • 84885463949 scopus 로고    scopus 로고
    • The roles of IRF-3 and IRF-7 in innate antiviral immunity against dengue virus
    • Chen HW, King K, Tu J, Sanchez M, Luster AD, Shresta S, (2013a). The roles of IRF-3 and IRF-7 in innate antiviral immunity against dengue virus. J Immunol 191: 4194-4201.
    • (2013) J Immunol , vol.191 , pp. 4194-4201
    • Chen, H.W.1    King, K.2    Tu, J.3    Sanchez, M.4    Luster, A.D.5    Shresta, S.6
  • 22
    • 84906898008 scopus 로고    scopus 로고
    • A critical role for interferon regulatory factor 9 in cerebral ischemic stroke
    • Chen HZ, Guo S, Li ZZ, Lu Y, Jiang DS, Zhang R, et al. (2014). A critical role for interferon regulatory factor 9 in cerebral ischemic stroke. J Neurosci 34: 11897-11912.
    • (2014) J Neurosci , vol.34 , pp. 11897-11912
    • Chen, H.Z.1    Guo, S.2    Li, Z.Z.3    Lu, Y.4    Jiang, D.S.5    Zhang, R.6
  • 23
    • 84873948410 scopus 로고    scopus 로고
    • Vinexin-beta protects against cardiac hypertrophy by blocking the Akt-dependent signalling pathway
    • Chen K, Gao L, Liu Y, Zhang Y, Jiang DS, Wei X, et al. (2013b). Vinexin-beta protects against cardiac hypertrophy by blocking the Akt-dependent signalling pathway. Basic Res Cardiol 108: 338.
    • (2013) Basic Res Cardiol , vol.108 , pp. 338
    • Chen, K.1    Gao, L.2    Liu, Y.3    Zhang, Y.4    Jiang, D.S.5    Wei, X.6
  • 24
    • 34548566398 scopus 로고    scopus 로고
    • Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus
    • Chen Z, Rijnbrand R, Jangra RK, Devaraj SG, Qu L, Ma Y, et al. (2007). Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus. Virology 366: 277-292.
    • (2007) Virology , vol.366 , pp. 277-292
    • Chen, Z.1    Rijnbrand, R.2    Jangra, R.K.3    Devaraj, S.G.4    Qu, L.5    Ma, Y.6
  • 25
    • 80054774247 scopus 로고    scopus 로고
    • The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling
    • Clark K, Takeuchi O, Akira S, Cohen P, (2011). The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling. Proc Natl Acad Sci U S A 108: 17093-17098.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 17093-17098
    • Clark, K.1    Takeuchi, O.2    Akira, S.3    Cohen, P.4
  • 26
    • 33947722603 scopus 로고    scopus 로고
    • TLR pathways and IFN-regulatory factors: To each its own
    • Colonna M, (2007). TLR pathways and IFN-regulatory factors: to each its own. Eur J Immunol 37: 306-309.
    • (2007) Eur J Immunol , vol.37 , pp. 306-309
    • Colonna, M.1
  • 27
    • 84880134559 scopus 로고    scopus 로고
    • Chloroquine pretreatment inhibits Toll-like receptor 3 signaling after stroke
    • Cui G, Ye X, Zuo T, Zhao H, Zhao Q, Chen W, et al. (2013). Chloroquine pretreatment inhibits Toll-like receptor 3 signaling after stroke. Neurosci Lett 548: 101-104.
    • (2013) Neurosci Lett , vol.548 , pp. 101-104
    • Cui, G.1    Ye, X.2    Zuo, T.3    Zhao, H.4    Zhao, Q.5    Chen, W.6
  • 28
    • 34247125683 scopus 로고    scopus 로고
    • Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation
    • Cunninghame Graham DS, Manku H, Wagner S, Reid J, Timms K, Gutin A, et al. (2007). Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation. Hum Mol Genet 16: 579-591.
    • (2007) Hum Mol Genet , vol.16 , pp. 579-591
    • Cunninghame Graham, D.S.1    Manku, H.2    Wagner, S.3    Reid, J.4    Timms, K.5    Gutin, A.6
  • 29
    • 34547631658 scopus 로고    scopus 로고
    • Cell-specific IRF-3 responses protect against West Nile virus infection by interferon-dependent and -independent mechanisms
    • Daffis S, Samuel MA, Keller BC, Gale M Jr, Diamond MS, (2007). Cell-specific IRF-3 responses protect against West Nile virus infection by interferon-dependent and -independent mechanisms. PLoS Pathog 3: e106.
    • (2007) PLoS Pathog , vol.3 , pp. e106
    • Daffis, S.1    Samuel, M.A.2    Keller, B.C.3    Gale, M.4    Diamond, M.S.5
  • 30
    • 50149119230 scopus 로고    scopus 로고
    • Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection
    • Daffis S, Samuel MA, Suthar MS, Keller BC, Gale M Jr, Diamond MS, (2008). Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection. J Virol 82: 8465-8475.
    • (2008) J Virol , vol.82 , pp. 8465-8475
    • Daffis, S.1    Samuel, M.A.2    Suthar, M.S.3    Keller, B.C.4    Gale, M.5    Diamond, M.S.6
  • 31
    • 73349108813 scopus 로고    scopus 로고
    • Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7
    • Daffis S, Suthar MS, Szretter KJ, Gale M Jr, Diamond MS, (2009). Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7. PLoS Pathog 5: e1000607.
    • (2009) PLoS Pathog , vol.5 , pp. e1000607
    • Daffis, S.1    Suthar, M.S.2    Szretter, K.J.3    Gale, M.4    Diamond, M.S.5
  • 32
    • 79956113412 scopus 로고    scopus 로고
    • The naturally attenuated Kunjin strain of West Nile virus shows enhanced sensitivity to the host type i interferon response
    • Daffis S, Lazear HM, Liu WJ, Audsley M, Engle M, Khromykh AA, et al. (2011). The naturally attenuated Kunjin strain of West Nile virus shows enhanced sensitivity to the host type I interferon response. J Virol 85: 5664-5668.
    • (2011) J Virol , vol.85 , pp. 5664-5668
    • Daffis, S.1    Lazear, H.M.2    Liu, W.J.3    Audsley, M.4    Engle, M.5    Khromykh, A.A.6
  • 33
    • 2142708560 scopus 로고    scopus 로고
    • The role of inflammation in vascular injury and repair
    • Davis C, Fischer J, Ley K, Sarembock IJ, (2003). The role of inflammation in vascular injury and repair. J Thromb Haemost 1: 1699-1709.
    • (2003) J Thromb Haemost , vol.1 , pp. 1699-1709
    • Davis, C.1    Fischer, J.2    Ley, K.3    Sarembock, I.J.4
  • 34
    • 80054926880 scopus 로고    scopus 로고
    • Micromanaging vascular smooth muscle cell differentiation and phenotypic modulation
    • Davis-Dusenbery BN, Wu C, Hata A, (2011). Micromanaging vascular smooth muscle cell differentiation and phenotypic modulation. Arterioscler Thromb Vasc Biol 31: 2370-2377.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2370-2377
    • Davis-Dusenbery, B.N.1    Wu, C.2    Hata, A.3
  • 35
    • 52949139429 scopus 로고    scopus 로고
    • A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia
    • Di Bernardo MC, Crowther-Swanepoel D, Broderick P, Webb E, Sellick G, Wild R, et al. (2008). A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia. Nat Genet 40: 1204-1210.
    • (2008) Nat Genet , vol.40 , pp. 1204-1210
    • Di Bernardo, M.C.1    Crowther-Swanepoel, D.2    Broderick, P.3    Webb, E.4    Sellick, G.5    Wild, R.6
  • 36
    • 33644802641 scopus 로고    scopus 로고
    • T-cell modulation of intimal thickening after vascular injury: The bimodal role of IFN-gamma in immune deficiency
    • Dimayuga PC, Li H, Chyu KY, Fredrikson GN, Nilsson J, Fishbein MC, et al. (2005). T-cell modulation of intimal thickening after vascular injury: the bimodal role of IFN-gamma in immune deficiency. Arterioscler Thromb Vasc Biol 25: 2528-2534.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2528-2534
    • Dimayuga, P.C.1    Li, H.2    Chyu, K.Y.3    Fredrikson, G.N.4    Nilsson, J.5    Fishbein, M.C.6
  • 37
    • 0029621889 scopus 로고
    • Interferon regulatory factor-2 physically interacts with NF-kappa B in vitro and inhibits NF-kappa B induction of major histocompatibility class i and beta 2-microglobulin gene expression in transfected human neuroblastoma cells
    • Drew PD, Franzoso G, Carlson LM, Biddison WE, Siebenlist U, Ozato K, (1995). Interferon regulatory factor-2 physically interacts with NF-kappa B in vitro and inhibits NF-kappa B induction of major histocompatibility class I and beta 2-microglobulin gene expression in transfected human neuroblastoma cells. J Neuroimmunol 63: 157-162.
    • (1995) J Neuroimmunol , vol.63 , pp. 157-162
    • Drew, P.D.1    Franzoso, G.2    Carlson, L.M.3    Biddison, W.E.4    Siebenlist, U.5    Ozato, K.6
  • 38
    • 39449102532 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma-mediated effects in the vasculature
    • Duan SZ, Usher MG, Mortensen RM, (2008). Peroxisome proliferator-activated receptor-gamma-mediated effects in the vasculature. Circ Res 102: 283-294.
    • (2008) Circ Res , vol.102 , pp. 283-294
    • Duan, S.Z.1    Usher, M.G.2    Mortensen, R.M.3
  • 39
    • 0036851826 scopus 로고    scopus 로고
    • Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies
    • Dzau VJ, Braun-Dullaeus RC, Sedding DG, (2002). Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies. Nat Med 8: 1249-1256.
    • (2002) Nat Med , vol.8 , pp. 1249-1256
    • Dzau, V.J.1    Braun-Dullaeus, R.C.2    Sedding, D.G.3
  • 40
    • 37449021303 scopus 로고    scopus 로고
    • Interferon regulatory factors are transcriptional regulators of adipogenesis
    • Eguchi J, Yan QW, Schones DE, Kamal M, Hsu CH, Zhang MQ, et al. (2008). Interferon regulatory factors are transcriptional regulators of adipogenesis. Cell Metab 7: 86-94.
    • (2008) Cell Metab , vol.7 , pp. 86-94
    • Eguchi, J.1    Yan, Q.W.2    Schones, D.E.3    Kamal, M.4    Hsu, C.H.5    Zhang, M.Q.6
  • 43
    • 41849149678 scopus 로고    scopus 로고
    • Regulation of interferon production and innate antiviral immunity through translational control of IRF-7
    • Erickson AK, Gale M Jr, (2008). Regulation of interferon production and innate antiviral immunity through translational control of IRF-7. Cell Res 18: 433-435.
    • (2008) Cell Res , vol.18 , pp. 433-435
    • Erickson, A.K.1    Gale, M.2
  • 44
    • 0032968759 scopus 로고    scopus 로고
    • Conserved transactivation domain shared by interferon regulatory factors and SMAD morphogens
    • Eroshkin A, Mushegian A, (1999). Conserved transactivation domain shared by interferon regulatory factors and SMAD morphogens. J Mol Med (Berl) 77: 403-405.
    • (1999) J Mol Med (Berl) , vol.77 , pp. 403-405
    • Eroshkin, A.1    Mushegian, A.2
  • 46
    • 78650637976 scopus 로고    scopus 로고
    • Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression
    • Feng D, Sangster-Guity N, Stone R, Korczeniewska J, Mancl ME, Fitzgerald-Bocarsly P, et al. (2010). Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. J Immunol 185: 6003-6012.
    • (2010) J Immunol , vol.185 , pp. 6003-6012
    • Feng, D.1    Sangster-Guity, N.2    Stone, R.3    Korczeniewska, J.4    Mancl, M.E.5    Fitzgerald-Bocarsly, P.6
  • 47
    • 0037143710 scopus 로고    scopus 로고
    • Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type i in cardiac myocytes
    • Fiedler B, Lohmann SM, Smolenski A, Linnemuller S, Pieske B, Schroder F, et al. (2002). Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes. Proc Natl Acad Sci U S A 99: 11363-11368.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 11363-11368
    • Fiedler, B.1    Lohmann, S.M.2    Smolenski, A.3    Linnemuller, S.4    Pieske, B.5    Schroder, F.6
  • 48
    • 0037687422 scopus 로고    scopus 로고
    • Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease
    • Foy E, Li K, Wang C, Sumpter R Jr, Ikeda M, Lemon SM, et al. (2003). Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease. Science 300: 1145-1148.
    • (2003) Science , vol.300 , pp. 1145-1148
    • Foy, E.1    Li, K.2    Wang, C.3    Sumpter, R.4    Ikeda, M.5    Lemon, S.M.6
  • 50
    • 79953707345 scopus 로고    scopus 로고
    • Association of a functional IRF7 variant with systemic lupus erythematosus
    • Fu Q, Zhao J, Qian X, Wong JL, Kaufman KM, Yu CY, et al. (2011). Association of a functional IRF7 variant with systemic lupus erythematosus. Arthritis Rheum 63: 749-754.
    • (2011) Arthritis Rheum , vol.63 , pp. 749-754
    • Fu, Q.1    Zhao, J.2    Qian, X.3    Wong, J.L.4    Kaufman, K.M.5    Yu, C.Y.6
  • 51
    • 0033568642 scopus 로고    scopus 로고
    • Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences
    • Fujii Y, Shimizu T, Kusumoto M, Kyogoku Y, Taniguchi T, Hakoshima T, (1999). Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. EMBO J 18: 5028-5041.
    • (1999) EMBO J , vol.18 , pp. 5028-5041
    • Fujii, Y.1    Shimizu, T.2    Kusumoto, M.3    Kyogoku, Y.4    Taniguchi, T.5    Hakoshima, T.6
  • 52
    • 33845439862 scopus 로고    scopus 로고
    • IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features
    • Gabriele L, Fragale A, Borghi P, Sestili P, Stellacci E, Venditti M, et al. (2006). IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features. J Leukoc Biol 80: 1500-1511.
    • (2006) J Leukoc Biol , vol.80 , pp. 1500-1511
    • Gabriele, L.1    Fragale, A.2    Borghi, P.3    Sestili, P.4    Stellacci, E.5    Venditti, M.6
  • 54
    • 0036534871 scopus 로고    scopus 로고
    • The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor
    • Gilliet M, Boonstra A, Paturel C, Antonenko S, Xu XL, Trinchieri G, et al. (2002). The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor. J Exp Med 195: 953-958.
    • (2002) J Exp Med , vol.195 , pp. 953-958
    • Gilliet, M.1    Boonstra, A.2    Paturel, C.3    Antonenko, S.4    Xu, X.L.5    Trinchieri, G.6
  • 55
    • 84893113465 scopus 로고    scopus 로고
    • Executive summary: Heart disease and stroke statistics - 2014 update: A report from the American Heart Association
    • Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Blaha MJ, et al. (2014). Executive summary: heart disease and stroke statistics-2014 update: a report from the American Heart Association. Circulation 129: 399-410.
    • (2014) Circulation , vol.129 , pp. 399-410
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3    Benjamin, E.J.4    Berry, J.D.5    Blaha, M.J.6
  • 56
    • 33846846415 scopus 로고    scopus 로고
    • Zinc-binding domain of rotavirus NSP1 is required for proteasome-dependent degradation of IRF3 and autoregulatory NSP1 stability
    • Graff JW, Ewen J, Ettayebi K, Hardy ME, (2007). Zinc-binding domain of rotavirus NSP1 is required for proteasome-dependent degradation of IRF3 and autoregulatory NSP1 stability. J Gen Virol 88 (Pt 2): 613-620.
    • (2007) J Gen Virol , vol.88 , pp. 613-620
    • Graff, J.W.1    Ewen, J.2    Ettayebi, K.3    Hardy, M.E.4
  • 57
    • 33646368404 scopus 로고    scopus 로고
    • A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
    • Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, Bauer JW, et al. (2006). A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat Genet 38: 550-555.
    • (2006) Nat Genet , vol.38 , pp. 550-555
    • Graham, R.R.1    Kozyrev, S.V.2    Baechler, E.C.3    Reddy, M.V.4    Plenge, R.M.5    Bauer, J.W.6
  • 58
    • 14044267522 scopus 로고    scopus 로고
    • Involvement of Toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus
    • Guillot L, Le Goffic R, Bloch S, Escriou N, Akira S, Chignard M, et al. (2005). Involvement of Toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus. J Biol Chem 280: 5571-5580.
    • (2005) J Biol Chem , vol.280 , pp. 5571-5580
    • Guillot, L.1    Le Goffic, R.2    Bloch, S.3    Escriou, N.4    Akira, S.5    Chignard, M.6
  • 59
    • 84899928972 scopus 로고    scopus 로고
    • IRF4 is a novel mediator for neuronal survival in ischaemic stroke
    • Guo S, Li ZZ, Jiang DS, Lu YY, Liu Y, Gao L, et al. (2014). IRF4 is a novel mediator for neuronal survival in ischaemic stroke. Cell Death Differ 21: 888-903.
    • (2014) Cell Death Differ , vol.21 , pp. 888-903
    • Guo, S.1    Li, Z.Z.2    Jiang, D.S.3    Lu, Y.Y.4    Liu, Y.5    Gao, L.6
  • 60
    • 33745013111 scopus 로고    scopus 로고
    • Oxidative stress and neurodegeneration: Where are we now?
    • Halliwell B, (2006). Oxidative stress and neurodegeneration: where are we now? J Neurochem 97: 1634-1658.
    • (2006) J Neurochem , vol.97 , pp. 1634-1658
    • Halliwell, B.1
  • 62
    • 0024380583 scopus 로고
    • Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes
    • Harada H, Fujita T, Miyamoto M, Kimura Y, Maruyama M, Furia A, et al. (1989). Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell 58: 729-739.
    • (1989) Cell , vol.58 , pp. 729-739
    • Harada, H.1    Fujita, T.2    Miyamoto, M.3    Kimura, Y.4    Maruyama, M.5    Furia, A.6
  • 63
    • 84873848690 scopus 로고    scopus 로고
    • Myocardial ischemia-reperfusion injury: A neglected therapeutic target
    • Hausenloy DJ, Yellon DM, (2013). Myocardial ischemia-reperfusion injury: a neglected therapeutic target. J Clin Invest 123: 92-100.
    • (2013) J Clin Invest , vol.123 , pp. 92-100
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 64
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • Heineke J, Molkentin JD, (2006). Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 7: 589-600.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 65
    • 0033635304 scopus 로고    scopus 로고
    • CD8(+) T-cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling
    • Hida S, Ogasawara K, Sato K, Abe M, Takayanagi H, Yokochi T, et al. (2000). CD8(+) T-cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling. Immunity 13: 643-655.
    • (2000) Immunity , vol.13 , pp. 643-655
    • Hida, S.1    Ogasawara, K.2    Sato, K.3    Abe, M.4    Takayanagi, H.5    Yokochi, T.6
  • 66
    • 49649125136 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3
    • Higgs R, Ni Gabhann J, Ben Larbi N, Breen EP, Fitzgerald KA, Jefferies CA, (2008). The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. J Immunol 181: 1780-1786.
    • (2008) J Immunol , vol.181 , pp. 1780-1786
    • Higgs, R.1    Ni Gabhann, J.2    Ben Larbi, N.3    Breen, E.P.4    Fitzgerald, K.A.5    Jefferies, C.A.6
  • 67
    • 77955627645 scopus 로고    scopus 로고
    • Self protection from anti-viral responses - Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-like receptors
    • Higgs R, Lazzari E, Wynne C, Ni Gabhann J, Espinosa A, Wahren-Herlenius M, et al. (2010). Self protection from anti-viral responses-Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-like receptors. PLoS ONE 5: e11776.
    • (2010) PLoS ONE , vol.5 , pp. e11776
    • Higgs, R.1    Lazzari, E.2    Wynne, C.3    Ni Gabhann, J.4    Espinosa, A.5    Wahren-Herlenius, M.6
  • 68
    • 33751232040 scopus 로고    scopus 로고
    • The NPro product of bovine viral diarrhea virus inhibits DNA binding by interferon regulatory factor 3 and targets it for proteasomal degradation
    • Hilton L, Moganeradj K, Zhang G, Chen YH, Randall RE, McCauley JW, et al. (2006). The NPro product of bovine viral diarrhea virus inhibits DNA binding by interferon regulatory factor 3 and targets it for proteasomal degradation. J Virol 80: 11723-11732.
    • (2006) J Virol , vol.80 , pp. 11723-11732
    • Hilton, L.1    Moganeradj, K.2    Zhang, G.3    Chen, Y.H.4    Randall, R.E.5    McCauley, J.W.6
  • 69
    • 34447499052 scopus 로고    scopus 로고
    • Triggering the innate antiviral response through IRF-3 activation
    • Hiscott J, (2007). Triggering the innate antiviral response through IRF-3 activation. J Biol Chem 282: 15325-15329.
    • (2007) J Biol Chem , vol.282 , pp. 15325-15329
    • Hiscott, J.1
  • 70
    • 54349126568 scopus 로고    scopus 로고
    • Molecular characterization of IRF3 and IRF7 in rainbow trout, Oncorhynchus mykiss: Functional analysis and transcriptional modulation
    • Holland JW, Bird S, Williamson B, Woudstra C, Mustafa A, Wang T, et al. (2008). Molecular characterization of IRF3 and IRF7 in rainbow trout, Oncorhynchus mykiss: functional analysis and transcriptional modulation. Mol Immunol 46: 269-285.
    • (2008) Mol Immunol , vol.46 , pp. 269-285
    • Holland, J.W.1    Bird, S.2    Williamson, B.3    Woudstra, C.4    Mustafa, A.5    Wang, T.6
  • 71
    • 33748051738 scopus 로고    scopus 로고
    • IRFs: Master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
    • Honda K, Taniguchi T, (2006b). IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol 6: 644-658.
    • (2006) Nat Rev Immunol , vol.6 , pp. 644-658
    • Honda, K.1    Taniguchi, T.2
  • 72
    • 17144404177 scopus 로고    scopus 로고
    • IRF-7 is the master regulator of type-I interferon-dependent immune responses
    • Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, et al. (2005). IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434: 772-777.
    • (2005) Nature , vol.434 , pp. 772-777
    • Honda, K.1    Yanai, H.2    Negishi, H.3    Asagiri, M.4    Sato, M.5    Mizutani, T.6
  • 73
    • 33748475531 scopus 로고    scopus 로고
    • Type i interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors
    • Honda K, Takaoka A, Taniguchi T, (2006a). Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity 25: 349-360.
    • (2006) Immunity , vol.25 , pp. 349-360
    • Honda, K.1    Takaoka, A.2    Taniguchi, T.3
  • 74
    • 27644553011 scopus 로고    scopus 로고
    • Interferon regulatory factor 4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPS
    • Honma K, Udono H, Kohno T, Yamamoto K, Ogawa A, Takemori T, et al. (2005). Interferon regulatory factor 4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPS. Proc Natl Acad Sci U S A 102: 16001-16006.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 16001-16006
    • Honma, K.1    Udono, H.2    Kohno, T.3    Yamamoto, K.4    Ogawa, A.5    Takemori, T.6
  • 75
    • 17544380854 scopus 로고    scopus 로고
    • Interferon-gamma induces AT(2) receptor expression in fibroblasts by JAK/STAT pathway and interferon regulatory factor-1
    • Horiuchi M, Hayashida W, Akishita M, Yamada S, Lehtonen JY, Tamura K, et al. (2000). Interferon-gamma induces AT(2) receptor expression in fibroblasts by JAK/STAT pathway and interferon regulatory factor-1. Circ Res 86: 233-240.
    • (2000) Circ Res , vol.86 , pp. 233-240
    • Horiuchi, M.1    Hayashida, W.2    Akishita, M.3    Yamada, S.4    Lehtonen, J.Y.5    Tamura, K.6
  • 76
    • 77955504366 scopus 로고    scopus 로고
    • Tumor suppressor A20 protects against cardiac hypertrophy and fibrosis by blocking transforming growth factor-beta-activated kinase 1-dependent signaling
    • Huang H, Tang QZ, Wang AB, Chen M, Yan L, Liu C, et al. (2010). Tumor suppressor A20 protects against cardiac hypertrophy and fibrosis by blocking transforming growth factor-beta-activated kinase 1-dependent signaling. Hypertension 56: 232-239.
    • (2010) Hypertension , vol.56 , pp. 232-239
    • Huang, H.1    Tang, Q.Z.2    Wang, A.B.3    Chen, M.4    Yan, L.5    Liu, C.6
  • 77
    • 28644433321 scopus 로고    scopus 로고
    • SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways
    • Huang J, Liu T, Xu LG, Chen D, Zhai Z, Shu HB, (2005). SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways. EMBO J 24: 4018-4028.
    • (2005) EMBO J , vol.24 , pp. 4018-4028
    • Huang, J.1    Liu, T.2    Xu, L.G.3    Chen, D.4    Zhai, Z.5    Shu, H.B.6
  • 78
    • 79961185942 scopus 로고    scopus 로고
    • Heritable gene targeting in zebrafish using customized TALENs
    • Huang P, Xiao A, Zhou M, Zhu Z, Lin S, Zhang B, (2011). Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol 29: 699-700.
    • (2011) Nat Biotechnol , vol.29 , pp. 699-700
    • Huang, P.1    Xiao, A.2    Zhou, M.3    Zhu, Z.4    Lin, S.5    Zhang, B.6
  • 79
    • 34250320958 scopus 로고    scopus 로고
    • PU.1, interferon regulatory factor (IRF) 2, and the interferon consensus sequence-binding protein (ICSBP/IRF8) cooperate to activate NF1 transcription in differentiating myeloid cells
    • Huang W, Horvath E, Eklund EA, (2007). PU.1, interferon regulatory factor (IRF) 2, and the interferon consensus sequence-binding protein (ICSBP/IRF8) cooperate to activate NF1 transcription in differentiating myeloid cells. J Biol Chem 282: 6629-6643.
    • (2007) J Biol Chem , vol.282 , pp. 6629-6643
    • Huang, W.1    Horvath, E.2    Eklund, E.A.3
  • 80
    • 58549094107 scopus 로고    scopus 로고
    • IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype
    • Huber M, Brustle A, Reinhard K, Guralnik A, Walter G, Mahiny A, et al. (2008). IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype. Proc Natl Acad Sci U S A 105: 20846-20851.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20846-20851
    • Huber, M.1    Brustle, A.2    Reinhard, K.3    Guralnik, A.4    Walter, G.5    Mahiny, A.6
  • 81
    • 34147208226 scopus 로고    scopus 로고
    • Interferon regulatory factor 7 is activated by a viral oncoprotein through RIP-dependent ubiquitination
    • Huye LE, Ning S, Kelliher M, Pagano JS, (2007). Interferon regulatory factor 7 is activated by a viral oncoprotein through RIP-dependent ubiquitination. Mol Cell Biol 27: 2910-2918.
    • (2007) Mol Cell Biol , vol.27 , pp. 2910-2918
    • Huye, L.E.1    Ning, S.2    Kelliher, M.3    Pagano, J.S.4
  • 82
    • 0033557359 scopus 로고    scopus 로고
    • The transcription factor interferon regulatory factor 1 is expressed after cerebral ischemia and contributes to ischemic brain injury
    • Iadecola C, Salkowski CA, Zhang F, Aber T, Nagayama M, Vogel SN, et al. (1999). The transcription factor interferon regulatory factor 1 is expressed after cerebral ischemia and contributes to ischemic brain injury. J Exp Med 189: 719-727.
    • (1999) J Exp Med , vol.189 , pp. 719-727
    • Iadecola, C.1    Salkowski, C.A.2    Zhang, F.3    Aber, T.4    Nagayama, M.5    Vogel, S.N.6
  • 83
    • 1642295557 scopus 로고    scopus 로고
    • Defective development of splenic and epidermal CD4+ dendritic cells in mice deficient for IFN regulatory factor-2
    • Ichikawa E, Hida S, Omatsu Y, Shimoyama S, Takahara K, Miyagawa S, et al. (2004). Defective development of splenic and epidermal CD4+ dendritic cells in mice deficient for IFN regulatory factor-2. Proc Natl Acad Sci U S A 101: 3909-3914.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3909-3914
    • Ichikawa, E.1    Hida, S.2    Omatsu, Y.3    Shimoyama, S.4    Takahara, K.5    Miyagawa, S.6
  • 84
    • 80054993002 scopus 로고    scopus 로고
    • Vascular inflammation and repair: Implications for re-endothelialization, restenosis, and stent thrombosis
    • Inoue T, Croce K, Morooka T, Sakuma M, Node K, Simon DI, (2011). Vascular inflammation and repair: implications for re-endothelialization, restenosis, and stent thrombosis. JACC Cardiovasc Interv 4: 1057-1066.
    • (2011) JACC Cardiovasc Interv , vol.4 , pp. 1057-1066
    • Inoue, T.1    Croce, K.2    Morooka, T.3    Sakuma, M.4    Node, K.5    Simon, D.I.6
  • 86
    • 40149089981 scopus 로고    scopus 로고
    • Gene structures and promoter characteristics of interferon regulatory factor 1 (IRF-1), IRF-2 and IRF-7 from snakehead Channa argus
    • Jia W, Guo Q, (2008). Gene structures and promoter characteristics of interferon regulatory factor 1 (IRF-1), IRF-2 and IRF-7 from snakehead Channa argus. Mol Immunol 45: 2419-2428.
    • (2008) Mol Immunol , vol.45 , pp. 2419-2428
    • Jia, W.1    Guo, Q.2
  • 87
    • 84878913857 scopus 로고    scopus 로고
    • Role of interferon regulatory factor 4 in the regulation of pathological cardiac hypertrophy
    • Jiang DS, Bian ZY, Zhang Y, Zhang SM, Liu Y, Zhang R, et al. (2013). Role of interferon regulatory factor 4 in the regulation of pathological cardiac hypertrophy. Hypertension 61: 1193-1202.
    • (2013) Hypertension , vol.61 , pp. 1193-1202
    • Jiang, D.S.1    Bian, Z.Y.2    Zhang, Y.3    Zhang, S.M.4    Liu, Y.5    Zhang, R.6
  • 88
    • 84902547677 scopus 로고    scopus 로고
    • Interferon regulatory factor 1 is required for cardiac remodeling in response to pressure overload
    • Jiang DS, Li L, Huang L, Gong J, Xia H, Liu X, et al. (2014a). Interferon regulatory factor 1 is required for cardiac remodeling in response to pressure overload. Hypertension 64: 77-86.
    • (2014) Hypertension , vol.64 , pp. 77-86
    • Jiang, D.S.1    Li, L.2    Huang, L.3    Gong, J.4    Xia, H.5    Liu, X.6
  • 89
    • 84897045727 scopus 로고    scopus 로고
    • Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy
    • Jiang DS, Liu Y, Zhou H, Zhang Y, Zhang XD, Zhang XF, et al. (2014b). Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy. Hypertension 63: 713-722.
    • (2014) Hypertension , vol.63 , pp. 713-722
    • Jiang, D.S.1    Liu, Y.2    Zhou, H.3    Zhang, Y.4    Zhang, X.D.5    Zhang, X.F.6
  • 90
    • 84891624887 scopus 로고    scopus 로고
    • Interferon regulatory factor 9 protects against cardiac hypertrophy by targeting myocardin
    • Jiang DS, Luo YX, Zhang R, Zhang XD, Chen HZ, Zhang Y, et al. (2014c). Interferon regulatory factor 9 protects against cardiac hypertrophy by targeting myocardin. Hypertension 63: 119-127.
    • (2014) Hypertension , vol.63 , pp. 119-127
    • Jiang, D.S.1    Luo, Y.X.2    Zhang, R.3    Zhang, X.D.4    Chen, H.Z.5    Zhang, Y.6
  • 91
    • 84894057277 scopus 로고    scopus 로고
    • IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling
    • Jiang DS, Wei X, Zhang XF, Liu Y, Zhang Y, Chen K, et al. (2014d). IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling. Nat Commun 5: 3303.
    • (2014) Nat Commun , vol.5 , pp. 3303
    • Jiang, D.S.1    Wei, X.2    Zhang, X.F.3    Liu, Y.4    Zhang, Y.5    Chen, K.6
  • 92
    • 84891632291 scopus 로고    scopus 로고
    • Signal regulatory protein-alpha protects against cardiac hypertrophy via the disruption of toll-like receptor 4 signaling
    • Jiang DS, Zhang XF, Gao L, Zong J, Zhou H, Liu Y, et al. (2014e). Signal regulatory protein-alpha protects against cardiac hypertrophy via the disruption of toll-like receptor 4 signaling. Hypertension 63: 96-104.
    • (2014) Hypertension , vol.63 , pp. 96-104
    • Jiang, D.S.1    Zhang, X.F.2    Gao, L.3    Zong, J.4    Zhou, H.5    Liu, Y.6
  • 93
    • 30344462965 scopus 로고    scopus 로고
    • Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex
    • Kanno Y, Levi BZ, Tamura T, Ozato K, (2005). Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex. J Interferon Cytokine Res 25: 770-779.
    • (2005) J Interferon Cytokine Res , vol.25 , pp. 770-779
    • Kanno, Y.1    Levi, B.Z.2    Tamura, T.3    Ozato, K.4
  • 94
    • 37349040852 scopus 로고    scopus 로고
    • The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T-cells
    • Kano S, Sato K, Morishita Y, Vollstedt S, Kim S, Bishop K, et al. (2008). The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T-cells. Nat Immunol 9: 34-41.
    • (2008) Nat Immunol , vol.9 , pp. 34-41
    • Kano, S.1    Sato, K.2    Morishita, Y.3    Vollstedt, S.4    Kim, S.5    Bishop, K.6
  • 96
    • 5444274514 scopus 로고    scopus 로고
    • Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
    • Kawai T, Sato S, Ishii KJ, Coban C, Hemmi H, Yamamoto M, et al. (2004). Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol 5: 1061-1068.
    • (2004) Nat Immunol , vol.5 , pp. 1061-1068
    • Kawai, T.1    Sato, S.2    Ishii, K.J.3    Coban, C.4    Hemmi, H.5    Yamamoto, M.6
  • 97
    • 78650710691 scopus 로고    scopus 로고
    • Molecular pathways underlying cardiac remodeling during pathophysiological stimulation
    • Kehat I, Molkentin JD, (2010). Molecular pathways underlying cardiac remodeling during pathophysiological stimulation. Circulation 122: 2727-2735.
    • (2010) Circulation , vol.122 , pp. 2727-2735
    • Kehat, I.1    Molkentin, J.D.2
  • 98
    • 84899484551 scopus 로고    scopus 로고
    • GCN5 is essential for IRF-4 gene expression followed by transcriptional activation of Blimp-1 in immature B cells
    • Kikuchi H, Nakayama M, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, et al. (2014). GCN5 is essential for IRF-4 gene expression followed by transcriptional activation of Blimp-1 in immature B cells. J Leukoc Biol 95: 399-404.
    • (2014) J Leukoc Biol , vol.95 , pp. 399-404
    • Kikuchi, H.1    Nakayama, M.2    Kuribayashi, F.3    Imajoh-Ohmi, S.4    Nishitoh, H.5    Takami, Y.6
  • 99
    • 0036498798 scopus 로고    scopus 로고
    • Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis
    • Ko J, Gendron-Fitzpatrick A, Splitter GA, (2002). Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis. J Immunol 168: 2433-2440.
    • (2002) J Immunol , vol.168 , pp. 2433-2440
    • Ko, J.1    Gendron-Fitzpatrick, A.2    Splitter, G.A.3
  • 100
    • 34250896716 scopus 로고    scopus 로고
    • Cutting edge: Autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages
    • Kong HJ, Anderson DE, Lee CH, Jang MK, Tamura T, Tailor P, et al. (2007). Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages. J Immunol 179: 26-30.
    • (2007) J Immunol , vol.179 , pp. 26-30
    • Kong, H.J.1    Anderson, D.E.2    Lee, C.H.3    Jang, M.K.4    Tamura, T.5    Tailor, P.6
  • 101
    • 33745173485 scopus 로고    scopus 로고
    • Suppression of class i and II histone deacetylases blunts pressure-overload cardiac hypertrophy
    • Kong Y, Tannous P, Lu G, Berenji K, Rothermel BA, Olson EN, et al. (2006). Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation 113: 2579-2588.
    • (2006) Circulation , vol.113 , pp. 2579-2588
    • Kong, Y.1    Tannous, P.2    Lu, G.3    Berenji, K.4    Rothermel, B.A.5    Olson, E.N.6
  • 102
    • 84872272223 scopus 로고    scopus 로고
    • An association study of functional polymorphic genes IRF-1, IFNGR-1, and IFN-gamma with disease progression, aspartate aminotransferase, alanine aminotransferase, and viral load in chronic hepatitis B and C
    • Korachi M, Ceran N, Adaleti R, Nigdelioglu A, Sokmen M, (2013). An association study of functional polymorphic genes IRF-1, IFNGR-1, and IFN-gamma with disease progression, aspartate aminotransferase, alanine aminotransferase, and viral load in chronic hepatitis B and C. Int J Infect Dis 17: e44-e49.
    • (2013) Int J Infect Dis , vol.17 , pp. e44-e49
    • Korachi, M.1    Ceran, N.2    Adaleti, R.3    Nigdelioglu, A.4    Sokmen, M.5
  • 103
    • 34047219787 scopus 로고    scopus 로고
    • Inhibition of intrinsic interferon-gamma function prevents neointima formation after balloon injury
    • Kusaba K, Kai H, Koga M, Takayama N, Ikeda A, Yasukawa H, et al. (2007). Inhibition of intrinsic interferon-gamma function prevents neointima formation after balloon injury. Hypertension 49: 909-915.
    • (2007) Hypertension , vol.49 , pp. 909-915
    • Kusaba, K.1    Kai, H.2    Koga, M.3    Takayama, N.4    Ikeda, A.5    Yasukawa, H.6
  • 104
    • 33846330908 scopus 로고    scopus 로고
    • Single-stranded RNA viruses inactivate the transcriptional activity of p53 but induce NOXA-dependent apoptosis via post-translational modifications of IRF-1, IRF-3 and CREB
    • Lallemand C, Blanchard B, Palmieri M, Lebon P, May E, Tovey MG, (2007). Single-stranded RNA viruses inactivate the transcriptional activity of p53 but induce NOXA-dependent apoptosis via post-translational modifications of IRF-1, IRF-3 and CREB. Oncogene 26: 328-338.
    • (2007) Oncogene , vol.26 , pp. 328-338
    • Lallemand, C.1    Blanchard, B.2    Palmieri, M.3    Lebon, P.4    May, E.5    Tovey, M.G.6
  • 105
    • 75749138095 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: Key players in the initiation and regulation of immune responses
    • Lande R, Gilliet M, (2010). Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses. Ann N Y Acad Sci 1183: 89-103.
    • (2010) Ann N y Acad Sci , vol.1183 , pp. 89-103
    • Lande, R.1    Gilliet, M.2
  • 106
    • 84875065899 scopus 로고    scopus 로고
    • IRF-3, IRF-5, and IRF-7 coordinately regulate the type i IFN response in myeloid dendritic cells downstream of MAVS signaling
    • Lazear HM, Lancaster A, Wilkins C, Suthar MS, Huang A, Vick SC, et al. (2012). IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling. PLoS Pathog 9: e1003118.
    • (2012) PLoS Pathog , vol.9 , pp. e1003118
    • Lazear, H.M.1    Lancaster, A.2    Wilkins, C.3    Suthar, M.S.4    Huang, A.5    Vick, S.C.6
  • 107
    • 84875065899 scopus 로고    scopus 로고
    • IRF-3, IRF-5, and IRF-7 coordinately regulate the type i IFN response in myeloid dendritic cells downstream of MAVS signaling
    • Lazear HM, Lancaster A, Wilkins C, Suthar MS, Huang A, Vick SC, et al. (2013). IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling. PLoS Pathog 9: e1003118.
    • (2013) PLoS Pathog , vol.9 , pp. e1003118
    • Lazear, H.M.1    Lancaster, A.2    Wilkins, C.3    Suthar, M.S.4    Huang, A.5    Vick, S.C.6
  • 108
    • 31344465701 scopus 로고    scopus 로고
    • E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells
    • Lazorchak AS, Schlissel MS, Zhuang Y, (2006). E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells. Mol Cell Biol 26: 810-821.
    • (2006) Mol Cell Biol , vol.26 , pp. 810-821
    • Lazorchak, A.S.1    Schlissel, M.S.2    Zhuang, Y.3
  • 109
    • 0142186757 scopus 로고    scopus 로고
    • IFN-alpha and IL-12 activate IFN regulatory factor 1 (IRF-1), IRF-4, and IRF-8 gene expression in human NK and T-cells
    • Lehtonen A, Lund R, Lahesmaa R, Julkunen I, Sareneva T, Matikainen S, (2003). IFN-alpha and IL-12 activate IFN regulatory factor 1 (IRF-1), IRF-4, and IRF-8 gene expression in human NK and T-cells. Cytokine 24: 81-90.
    • (2003) Cytokine , vol.24 , pp. 81-90
    • Lehtonen, A.1    Lund, R.2    Lahesmaa, R.3    Julkunen, I.4    Sareneva, T.5    Matikainen, S.6
  • 110
    • 84860216398 scopus 로고    scopus 로고
    • Toll-like receptor 7 preconditioning induces robust neuroprotection against stroke by a novel type i interferon-mediated mechanism
    • Leung PY, Stevens SL, Packard AE, Lessov NS, Yang T, Conrad VK, et al. (2012). Toll-like receptor 7 preconditioning induces robust neuroprotection against stroke by a novel type I interferon-mediated mechanism. Stroke 43: 1383-1389.
    • (2012) Stroke , vol.43 , pp. 1383-1389
    • Leung, P.Y.1    Stevens, S.L.2    Packard, A.E.3    Lessov, N.S.4    Yang, T.5    Conrad, V.K.6
  • 111
    • 77956386624 scopus 로고    scopus 로고
    • Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload
    • Li H, He C, Feng J, Zhang Y, Tang Q, Bian Z, et al. (2010a). Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload. Proc Natl Acad Sci U S A 107: 13818-13823.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13818-13823
    • Li, H.1    He, C.2    Feng, J.3    Zhang, Y.4    Tang, Q.5    Bian, Z.6
  • 112
    • 78650415010 scopus 로고    scopus 로고
    • Cellular FLICE-inhibitory protein protects against cardiac remodeling induced by angiotensin II in mice
    • Li H, Tang QZ, Liu C, Moon M, Chen M, Yan L, et al. (2010b). Cellular FLICE-inhibitory protein protects against cardiac remodeling induced by angiotensin II in mice. Hypertension 56: 1109-1117.
    • (2010) Hypertension , vol.56 , pp. 1109-1117
    • Li, H.1    Tang, Q.Z.2    Liu, C.3    Moon, M.4    Chen, M.5    Yan, L.6
  • 113
    • 80053570632 scopus 로고    scopus 로고
    • Free fatty acids induce endothelial dysfunction and activate protein kinase C and nuclear factor-kappaB pathway in rat aorta
    • Li H, Li H, Bao Y, Zhang X, Yu Y, (2011a). Free fatty acids induce endothelial dysfunction and activate protein kinase C and nuclear factor-kappaB pathway in rat aorta. Int J Cardiol 152: 218-224.
    • (2011) Int J Cardiol , vol.152 , pp. 218-224
    • Li, H.1    Li, H.2    Bao, Y.3    Zhang, X.4    Yu, Y.5
  • 114
    • 84902543223 scopus 로고    scopus 로고
    • Caspase recruitment domain 6 protects against cardiac hypertrophy in response to pressure overload
    • Li L, Chen W, Zhu Y, Wang X, Jiang DS, Huang F, et al. (2014). Caspase recruitment domain 6 protects against cardiac hypertrophy in response to pressure overload. Hypertension 64: 94-102.
    • (2014) Hypertension , vol.64 , pp. 94-102
    • Li, L.1    Chen, W.2    Zhu, Y.3    Wang, X.4    Jiang, D.S.5    Huang, F.6
  • 115
    • 80755126865 scopus 로고    scopus 로고
    • Mapping a dynamic innate immunity protein interaction network regulating type i interferon production
    • Li S, Wang L, Berman M, Kong YY, Dorf ME, (2011b). Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. Immunity 35: 426-440.
    • (2011) Immunity , vol.35 , pp. 426-440
    • Li, S.1    Wang, L.2    Berman, M.3    Kong, Y.Y.4    Dorf, M.E.5
  • 116
    • 67650805611 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 exerts inhibitory effect on neointimal formation after vascular injury
    • Li Z, Wang ZG, Bian C, Chen XD, Li JW, Chen X, et al. (2009). Interferon regulatory factor-1 exerts inhibitory effect on neointimal formation after vascular injury. Chin Med Sci J 24: 91-96.
    • (2009) Chin Med Sci J , vol.24 , pp. 91-96
    • Li, Z.1    Wang, Z.G.2    Bian, C.3    Chen, X.D.4    Li, J.W.5    Chen, X.6
  • 117
    • 33646685675 scopus 로고    scopus 로고
    • PPARgamma gene transfer sustains apoptosis, inhibits vascular smooth muscle cell proliferation, and reduces neointima formation after balloon injury in rats
    • Lim S, Jin CJ, Kim M, Chung SS, Park HS, Lee IK, et al. (2006). PPARgamma gene transfer sustains apoptosis, inhibits vascular smooth muscle cell proliferation, and reduces neointima formation after balloon injury in rats. Arterioscler Thromb Vasc Biol 26: 808-813.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 808-813
    • Lim, S.1    Jin, C.J.2    Kim, M.3    Chung, S.S.4    Park, H.S.5    Lee, I.K.6
  • 118
    • 1042279525 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 mediates PPARgamma-induced apoptosis in vascular smooth muscle cells
    • Lin Y, Zhu X, McLntee FL, Xiao H, Zhang J, Fu M, et al. (2004). Interferon regulatory factor-1 mediates PPARgamma-induced apoptosis in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 24: 257-263.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 257-263
    • Lin, Y.1    Zhu, X.2    McLntee, F.L.3    Xiao, H.4    Zhang, J.5    Fu, M.6
  • 119
    • 0033997613 scopus 로고    scopus 로고
    • The emerging role of IL-15 in NK-cell development
    • Liu CC, Perussia B, Young JD, (2000). The emerging role of IL-15 in NK-cell development. Immunol Today 21: 113-116.
    • (2000) Immunol Today , vol.21 , pp. 113-116
    • Liu, C.C.1    Perussia, B.2    Young, J.D.3
  • 120
    • 84891355711 scopus 로고    scopus 로고
    • Toll-interacting protein (Tollip) negatively regulates pressure overload-induced ventricular hypertrophy in mice
    • Liu Y, Jiang XL, Liu Y, Jiang DS, Zhang Y, Zhang R, et al. (2014). Toll-interacting protein (Tollip) negatively regulates pressure overload-induced ventricular hypertrophy in mice. Cardiovasc Res 101: 87-96.
    • (2014) Cardiovasc Res , vol.101 , pp. 87-96
    • Liu, Y.1    Jiang, X.L.2    Liu, Y.3    Jiang, D.S.4    Zhang, Y.5    Zhang, R.6
  • 121
    • 84872013157 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy
    • Lu J, Bian ZY, Zhang R, Zhang Y, Liu C, Yan L, et al. (2013a). Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy. Basic Res Cardiol 108: 326.
    • (2013) Basic Res Cardiol , vol.108 , pp. 326
    • Lu, J.1    Bian, Z.Y.2    Zhang, R.3    Zhang, Y.4    Liu, C.5    Yan, L.6
  • 122
    • 52049093870 scopus 로고    scopus 로고
    • Interferon regulatory factor 4 and 8 in B-cell development
    • Lu R, (2008). Interferon regulatory factor 4 and 8 in B-cell development. Trends Immunol 29: 487-492.
    • (2008) Trends Immunol , vol.29 , pp. 487-492
    • Lu, R.1
  • 123
    • 0038506030 scopus 로고    scopus 로고
    • IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development
    • Lu R, Medina KL, Lancki DW, Singh H, (2003). IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev 17: 1703-1708.
    • (2003) Genes Dev , vol.17 , pp. 1703-1708
    • Lu, R.1    Medina, K.L.2    Lancki, D.W.3    Singh, H.4
  • 124
    • 84889255131 scopus 로고    scopus 로고
    • TRAF1 is a critical regulator of cerebral ischaemia-reperfusion injury and neuronal death
    • Lu YY, Li ZZ, Jiang DS, Wang L, Zhang Y, Chen K, et al. (2013b). TRAF1 is a critical regulator of cerebral ischaemia-reperfusion injury and neuronal death. Nat Commun 4: 2852.
    • (2013) Nat Commun , vol.4 , pp. 2852
    • Lu, Y.Y.1    Li, Z.Z.2    Jiang, D.S.3    Wang, L.4    Zhang, Y.5    Chen, K.6
  • 125
    • 0034144377 scopus 로고    scopus 로고
    • Posttranslational regulation of IRF-4 activity by the immunophilin FKBP52
    • Mamane Y, Sharma S, Petropoulos L, Lin R, Hiscott J, (2000). Posttranslational regulation of IRF-4 activity by the immunophilin FKBP52. Immunity 12: 129-140.
    • (2000) Immunity , vol.12 , pp. 129-140
    • Mamane, Y.1    Sharma, S.2    Petropoulos, L.3    Lin, R.4    Hiscott, J.5
  • 126
    • 68549089184 scopus 로고    scopus 로고
    • Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: A critical role for IRF3
    • Marsh B, Stevens SL, Packard AE, Gopalan B, Hunter B, Leung PY, et al. (2009a). Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: a critical role for IRF3. J Neurosci 29: 9839-9849.
    • (2009) J Neurosci , vol.29 , pp. 9839-9849
    • Marsh, B.1    Stevens, S.L.2    Packard, A.E.3    Gopalan, B.4    Hunter, B.5    Leung, P.Y.6
  • 127
    • 38749121741 scopus 로고    scopus 로고
    • Toll-like receptors: Novel pharmacological targets for the treatment of neurological diseases
    • Marsh BJ, Stenzel-Poore MP, (2008). Toll-like receptors: novel pharmacological targets for the treatment of neurological diseases. Curr Opin Pharmacol 8: 8-13.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 8-13
    • Marsh, B.J.1    Stenzel-Poore, M.P.2
  • 128
    • 59349116736 scopus 로고    scopus 로고
    • Toll-like receptor signaling in endogenous neuroprotection and stroke
    • Marsh BJ, Williams-Karnesky RL, Stenzel-Poore MP, (2009b). Toll-like receptor signaling in endogenous neuroprotection and stroke. Neuroscience 158: 1007-1020.
    • (2009) Neuroscience , vol.158 , pp. 1007-1020
    • Marsh, B.J.1    Williams-Karnesky, R.L.2    Stenzel-Poore, M.P.3
  • 129
    • 15044348013 scopus 로고    scopus 로고
    • Role of acetylases and deacetylase inhibitors in IRF-1-mediated HIV-1 long terminal repeat transcription
    • Marsili G, Remoli AL, Sgarbanti M, Battistini A, (2004). Role of acetylases and deacetylase inhibitors in IRF-1-mediated HIV-1 long terminal repeat transcription. Ann N Y Acad Sci 1030: 636-643.
    • (2004) Ann N y Acad Sci , vol.1030 , pp. 636-643
    • Marsili, G.1    Remoli, A.L.2    Sgarbanti, M.3    Battistini, A.4
  • 130
    • 79952207449 scopus 로고    scopus 로고
    • Histone acetyltransferases as regulators of nonhistone proteins: The role of interferon regulatory factor acetylation on gene transcription
    • Masumi A, (2011). Histone acetyltransferases as regulators of nonhistone proteins: the role of interferon regulatory factor acetylation on gene transcription. J Biomed Biotechnol 2011: 640610.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 640610
    • Masumi, A.1
  • 131
    • 0037032471 scopus 로고    scopus 로고
    • IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages
    • Masumi A, Tamaoki S, Wang IM, Ozato K, Komuro K, (2002). IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages. FEBS Lett 531: 348-353.
    • (2002) FEBS Lett , vol.531 , pp. 348-353
    • Masumi, A.1    Tamaoki, S.2    Wang, I.M.3    Ozato, K.4    Komuro, K.5
  • 132
    • 0038491558 scopus 로고    scopus 로고
    • Interferon regulatory factor-2 regulates cell growth through its acetylation
    • Masumi A, Yamakawa Y, Fukazawa H, Ozato K, Komuro K, (2003). Interferon regulatory factor-2 regulates cell growth through its acetylation. J Biol Chem 278: 25401-25407.
    • (2003) J Biol Chem , vol.278 , pp. 25401-25407
    • Masumi, A.1    Yamakawa, Y.2    Fukazawa, H.3    Ozato, K.4    Komuro, K.5
  • 133
    • 5044220930 scopus 로고    scopus 로고
    • IDO expression by dendritic cells: Tolerance and tryptophan catabolism
    • Mellor AL, Munn DH, (2004). IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 4: 762-774.
    • (2004) Nat Rev Immunol , vol.4 , pp. 762-774
    • Mellor, A.L.1    Munn, D.H.2
  • 134
    • 33947627724 scopus 로고    scopus 로고
    • Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction
    • Melroe GT, Silva L, Schaffer PA, Knipe DM, (2007). Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction. Virology 360: 305-321.
    • (2007) Virology , vol.360 , pp. 305-321
    • Melroe, G.T.1    Silva, L.2    Schaffer, P.A.3    Knipe, D.M.4
  • 135
    • 0037870478 scopus 로고    scopus 로고
    • Serum response factor: Toggling between disparate programs of gene expression
    • Miano JM, (2003). Serum response factor: toggling between disparate programs of gene expression. J Mol Cell Cardiol 35: 577-593.
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 577-593
    • Miano, J.M.1
  • 136
    • 84873602003 scopus 로고    scopus 로고
    • Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis
    • Mildner A, Chapnik E, Manor O, Yona S, Kim KW, Aychek T, et al. (2013). Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis. Blood 121: 1016-1027.
    • (2013) Blood , vol.121 , pp. 1016-1027
    • Mildner, A.1    Chapnik, E.2    Manor, O.3    Yona, S.4    Kim, K.W.5    Aychek, T.6
  • 137
    • 0023788435 scopus 로고
    • Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements
    • Miyamoto M, Fujita T, Kimura Y, Maruyama M, Harada H, Sudo Y, et al. (1988). Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements. Cell 54: 903-913.
    • (1988) Cell , vol.54 , pp. 903-913
    • Miyamoto, M.1    Fujita, T.2    Kimura, Y.3    Maruyama, M.4    Harada, H.5    Sudo, Y.6
  • 138
    • 1642297150 scopus 로고    scopus 로고
    • Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation
    • Mori M, Yoneyama M, Ito T, Takahashi K, Inagaki F, Fujita T, (2004). Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation. J Biol Chem 279: 9698-9702.
    • (2004) J Biol Chem , vol.279 , pp. 9698-9702
    • Mori, M.1    Yoneyama, M.2    Ito, T.3    Takahashi, K.4    Inagaki, F.5    Fujita, T.6
  • 139
    • 84882923542 scopus 로고    scopus 로고
    • Synergistic control of herpes simplex virus pathogenesis by IRF-3, and IRF-7 revealed through non-invasive bioluminescence imaging
    • Murphy AA, Rosato PC, Parker ZM, Khalenkov A, Leib DA, (2013). Synergistic control of herpes simplex virus pathogenesis by IRF-3, and IRF-7 revealed through non-invasive bioluminescence imaging. Virology 444: 71-79.
    • (2013) Virology , vol.444 , pp. 71-79
    • Murphy, A.A.1    Rosato, P.C.2    Parker, Z.M.3    Khalenkov, A.4    Leib, D.A.5
  • 140
    • 78650938218 scopus 로고    scopus 로고
    • Docking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIP
    • Narayan V, Pion E, Landre V, Muller P, Ball KL, (2011). Docking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIP. J Biol Chem 286: 607-619.
    • (2011) J Biol Chem , vol.286 , pp. 607-619
    • Narayan, V.1    Pion, E.2    Landre, V.3    Muller, P.4    Ball, K.L.5
  • 143
    • 30544447047 scopus 로고    scopus 로고
    • Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
    • Oganesyan G, Saha SK, Guo B, He JQ, Shahangian A, Zarnegar B, et al. (2006). Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature 439: 208-211.
    • (2006) Nature , vol.439 , pp. 208-211
    • Oganesyan, G.1    Saha, S.K.2    Guo, B.3    He, J.Q.4    Shahangian, A.5    Zarnegar, B.6
  • 144
    • 84862496763 scopus 로고    scopus 로고
    • The immunobiology of Ro52 (TRIM21) in autoimmunity: A critical review
    • Oke V, Wahren-Herlenius M, (2012). The immunobiology of Ro52 (TRIM21) in autoimmunity: a critical review. J Autoimmun 39: 77-82.
    • (2012) J Autoimmun , vol.39 , pp. 77-82
    • Oke, V.1    Wahren-Herlenius, M.2
  • 145
    • 40649114040 scopus 로고    scopus 로고
    • HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation
    • Okumura A, Alce T, Lubyova B, Ezelle H, Strebel K, Pitha PM, (2008). HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation. Virology 373: 85-97.
    • (2008) Virology , vol.373 , pp. 85-97
    • Okumura, A.1    Alce, T.2    Lubyova, B.3    Ezelle, H.4    Strebel, K.5    Pitha, P.M.6
  • 146
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill LA, Bowie AG, (2007). The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 7: 353-364.
    • (2007) Nat Rev Immunol , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 147
    • 34547930163 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch
    • Panne D, McWhirter SM, Maniatis T, Harrison SC, (2007). Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch. J Biol Chem 282: 22816-22822.
    • (2007) J Biol Chem , vol.282 , pp. 22816-22822
    • Panne, D.1    McWhirter, S.M.2    Maniatis, T.3    Harrison, S.C.4
  • 148
    • 13444258721 scopus 로고    scopus 로고
    • N-ras-induced growth suppression of myeloid cells is mediated by IRF-1
    • Passioura T, Dolnikov A, Shen S, Symonds G, (2005). N-ras-induced growth suppression of myeloid cells is mediated by IRF-1. Cancer Res 65: 797-804.
    • (2005) Cancer Res , vol.65 , pp. 797-804
    • Passioura, T.1    Dolnikov, A.2    Shen, S.3    Symonds, G.4
  • 149
    • 84891791940 scopus 로고    scopus 로고
    • The IUPHAR/BPS Guide to PHARMACOLOGY: An expert-driven knowledge base of drug targets and their ligands
    • NC-IUPHAR
    • Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, et al.; NC-IUPHAR (2014). The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledge base of drug targets and their ligands. Nucl Acids Res 42 (Database Issue): D1098-D1106.
    • (2014) Nucl Acids Res , vol.42 , Issue.DATABASE ISSUE , pp. D1098-D1106
    • Pawson, A.J.1    Sharman, J.L.2    Benson, H.E.3    Faccenda, E.4    Alexander, S.P.5    Buneman, O.P.6
  • 150
    • 0036179847 scopus 로고    scopus 로고
    • The role of IRF-4 in B and T-cell activation and differentiation
    • Pernis AB, (2002). The role of IRF-4 in B and T-cell activation and differentiation. J Interferon Cytokine Res 22: 111-120.
    • (2002) J Interferon Cytokine Res , vol.22 , pp. 111-120
    • Pernis, A.B.1
  • 151
    • 62149124822 scopus 로고    scopus 로고
    • Role of Mdm2 acid domain interactions in recognition and ubiquitination of the transcription factor IRF-2
    • Pettersson S, Kelleher M, Pion E, Wallace M, Ball KL, (2009). Role of Mdm2 acid domain interactions in recognition and ubiquitination of the transcription factor IRF-2. Biochem J 418: 575-585.
    • (2009) Biochem J , vol.418 , pp. 575-585
    • Pettersson, S.1    Kelleher, M.2    Pion, E.3    Wallace, M.4    Ball, K.L.5
  • 152
    • 84888086101 scopus 로고    scopus 로고
    • Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain
    • Piao W, Ru LW, Piepenbrink KH, Sundberg EJ, Vogel SN, Toshchakov VY, (2013). Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain. Proc Natl Acad Sci U S A 110: 19036-19041.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 19036-19041
    • Piao, W.1    Ru, L.W.2    Piepenbrink, K.H.3    Sundberg, E.J.4    Vogel, S.N.5    Toshchakov, V.Y.6
  • 153
  • 154
    • 67649185209 scopus 로고    scopus 로고
    • Role of the IRF-1 enhancer domain in signalling polyubiquitination and degradation
    • Pion E, Narayan V, Eckert M, Ball KL, (2009). Role of the IRF-1 enhancer domain in signalling polyubiquitination and degradation. Cell Signal 21: 1479-1487.
    • (2009) Cell Signal , vol.21 , pp. 1479-1487
    • Pion, E.1    Narayan, V.2    Eckert, M.3    Ball, K.L.4
  • 155
    • 21444443078 scopus 로고    scopus 로고
    • Tissue-specific positive feedback requirements for production of type i interferon following virus infection
    • Prakash A, Smith E, Lee CK, Levy DE, (2005). Tissue-specific positive feedback requirements for production of type I interferon following virus infection. J Biol Chem 280: 18651-18657.
    • (2005) J Biol Chem , vol.280 , pp. 18651-18657
    • Prakash, A.1    Smith, E.2    Lee, C.K.3    Levy, D.E.4
  • 156
    • 84859612798 scopus 로고    scopus 로고
    • Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type i interferon production and antibody responses
    • Purtha WE, Swiecki M, Colonna M, Diamond MS, Bhattacharya D, (2012). Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses. Proc Natl Acad Sci U S A 109: E898-E904.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. E898-E904
    • Purtha, W.E.1    Swiecki, M.2    Colonna, M.3    Diamond, M.S.4    Bhattacharya, D.5
  • 157
    • 84859744042 scopus 로고    scopus 로고
    • Interferon regulatory factor 1 transactivates expression of human DNA polymerase eta in response to carcinogen N-methyl-N′-nitro-N-nitrosoguanidine
    • Qi H, Zhu H, Lou M, Fan Y, Liu H, Shen J, et al. (2012). Interferon regulatory factor 1 transactivates expression of human DNA polymerase eta in response to carcinogen N-methyl-N′-nitro-N-nitrosoguanidine. J Biol Chem 287: 12622-12633.
    • (2012) J Biol Chem , vol.287 , pp. 12622-12633
    • Qi, H.1    Zhu, H.2    Lou, M.3    Fan, Y.4    Liu, H.5    Shen, J.6
  • 158
    • 0036892007 scopus 로고    scopus 로고
    • Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia
    • Raghavendra Rao VL, Bowen KK, Dhodda VK, Song G, Franklin JL, Gavva NR, et al. (2002). Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia. J Neurochem 83: 1072-1086.
    • (2002) J Neurochem , vol.83 , pp. 1072-1086
    • Raghavendra Rao, V.L.1    Bowen, K.K.2    Dhodda, V.K.3    Song, G.4    Franklin, J.L.5    Gavva, N.R.6
  • 159
    • 0037089575 scopus 로고    scopus 로고
    • Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression
    • Rengarajan J, Mowen KA, McBride KD, Smith ED, Singh H, Glimcher LH, (2002). Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J Exp Med 195: 1003-1012.
    • (2002) J Exp Med , vol.195 , pp. 1003-1012
    • Rengarajan, J.1    Mowen, K.A.2    McBride, K.D.3    Smith, E.D.4    Singh, H.5    Glimcher, L.H.6
  • 160
    • 81255210846 scopus 로고    scopus 로고
    • IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes
    • Restivo G, Nguyen BC, Dziunycz P, Ristorcelli E, Ryan RJ, Ozuysal OY, et al. (2011). IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes. EMBO J 30: 4571-4585.
    • (2011) EMBO J , vol.30 , pp. 4571-4585
    • Restivo, G.1    Nguyen, B.C.2    Dziunycz, P.3    Ristorcelli, E.4    Ryan, R.J.5    Ozuysal, O.Y.6
  • 161
    • 33947369830 scopus 로고    scopus 로고
    • The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) induces degradation of interferon response factor 3 and, consequently, inhibits beta interferon promoter activity
    • Saira K, Zhou Y, Jones C, (2007). The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) induces degradation of interferon response factor 3 and, consequently, inhibits beta interferon promoter activity. J Virol 81: 3077-3086.
    • (2007) J Virol , vol.81 , pp. 3077-3086
    • Saira, K.1    Zhou, Y.2    Jones, C.3
  • 162
    • 33744499683 scopus 로고    scopus 로고
    • Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1
    • Saitoh T, Tun-Kyi A, Ryo A, Yamamoto M, Finn G, Fujita T, et al. (2006). Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1. Nat Immunol 7: 598-605.
    • (2006) Nat Immunol , vol.7 , pp. 598-605
    • Saitoh, T.1    Tun-Kyi, A.2    Ryo, A.3    Yamamoto, M.4    Finn, G.5    Fujita, T.6
  • 163
    • 0037418939 scopus 로고    scopus 로고
    • Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter
    • Sanbe A, Gulick J, Hanks MC, Liang Q, Osinska H, Robbins J, (2003). Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter. Circ Res 92: 609-616.
    • (2003) Circ Res , vol.92 , pp. 609-616
    • Sanbe, A.1    Gulick, J.2    Hanks, M.C.3    Liang, Q.4    Osinska, H.5    Robbins, J.6
  • 164
    • 84876122915 scopus 로고    scopus 로고
    • Pathogen recognition receptors: Ligands and signaling pathways by Toll-like receptors
    • Sasai M, Yamamoto M, (2013). Pathogen recognition receptors: ligands and signaling pathways by Toll-like receptors. Int Rev Immunol 32: 116-133.
    • (2013) Int Rev Immunol , vol.32 , pp. 116-133
    • Sasai, M.1    Yamamoto, M.2
  • 165
    • 0033680737 scopus 로고    scopus 로고
    • Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction
    • Sato M, Suemori H, Hata N, Asagiri M, Ogasawara K, Nakao K, et al. (2000). Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity 13: 539-548.
    • (2000) Immunity , vol.13 , pp. 539-548
    • Sato, M.1    Suemori, H.2    Hata, N.3    Asagiri, M.4    Ogasawara, K.5    Nakao, K.6
  • 166
    • 77449101221 scopus 로고    scopus 로고
    • Regulation of immunity and oncogenesis by the IRF transcription factor family
    • Savitsky D, Tamura T, Yanai H, Taniguchi T, (2010). Regulation of immunity and oncogenesis by the IRF transcription factor family. Cancer Immunol Immunother 59: 489-510.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 489-510
    • Savitsky, D.1    Tamura, T.2    Yanai, H.3    Taniguchi, T.4
  • 167
    • 84886816333 scopus 로고    scopus 로고
    • Cross talk between Wnt/beta-catenin and Irf8 in leukemia progression and drug resistance
    • Scheller M, Schonheit J, Zimmermann K, Leser U, Rosenbauer F, Leutz A, (2013). Cross talk between Wnt/beta-catenin and Irf8 in leukemia progression and drug resistance. J Exp Med 210: 2239-2256.
    • (2013) J Exp Med , vol.210 , pp. 2239-2256
    • Scheller, M.1    Schonheit, J.2    Zimmermann, K.3    Leser, U.4    Rosenbauer, F.5    Leutz, A.6
  • 168
    • 0037011021 scopus 로고    scopus 로고
    • ICSBP is essential for the development of mouse type i interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells
    • Schiavoni G, Mattei F, Sestili P, Borghi P, Venditti M, Morse HC 3rd, et al. (2002). ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells. J Exp Med 196: 1415-1425.
    • (2002) J Exp Med , vol.196 , pp. 1415-1425
    • Schiavoni, G.1    Mattei, F.2    Sestili, P.3    Borghi, P.4    Venditti, M.5    Morse, H.C.6
  • 169
    • 84886672246 scopus 로고    scopus 로고
    • Immune mechanisms in hypertension and vascular injury
    • Schiffrin EL, (2014). Immune mechanisms in hypertension and vascular injury. Clin Sci (Lond) 126: 267-274.
    • (2014) Clin Sci (Lond) , vol.126 , pp. 267-274
    • Schiffrin, E.L.1
  • 170
    • 33947717604 scopus 로고    scopus 로고
    • Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-beta production in myeloid dendritic cells
    • Schmitz F, Heit A, Guggemoos S, Krug A, Mages J, Schiemann M, et al. (2007). Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-beta production in myeloid dendritic cells. Eur J Immunol 37: 315-327.
    • (2007) Eur J Immunol , vol.37 , pp. 315-327
    • Schmitz, F.1    Heit, A.2    Guggemoos, S.3    Krug, A.4    Mages, J.5    Schiemann, M.6
  • 171
    • 80052989433 scopus 로고    scopus 로고
    • Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation
    • Sears N, Sen GC, Stark GR, Chattopadhyay S, (2011). Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation. J Biol Chem 286: 33037-33044.
    • (2011) J Biol Chem , vol.286 , pp. 33037-33044
    • Sears, N.1    Sen, G.C.2    Stark, G.R.3    Chattopadhyay, S.4
  • 172
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3
    • Seth RB, Sun L, Ea C-K, Chen ZJ, (2005). Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3. Cell 122: 669-682.
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.-K.3    Chen, Z.J.4
  • 173
    • 84898960143 scopus 로고    scopus 로고
    • Inflammatory response to Porphyromonas gingivalis partially requires interferon regulatory factor (IRF) 3
    • Shaik-Dasthagirisaheb YB, Huang N, Gibson FC 3rd, (2014). Inflammatory response to Porphyromonas gingivalis partially requires interferon regulatory factor (IRF) 3. Innate Immun 20: 312-319.
    • (2014) Innate Immun , vol.20 , pp. 312-319
    • Shaik-Dasthagirisaheb, Y.B.1    Huang, N.2    Gibson, F.C.3
  • 175
    • 13844292408 scopus 로고    scopus 로고
    • Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
    • Sigurdsson S, Nordmark G, Goring HH, Lindroos K, Wiman AC, Sturfelt G, et al. (2005). Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet 76: 528-537.
    • (2005) Am J Hum Genet , vol.76 , pp. 528-537
    • Sigurdsson, S.1    Nordmark, G.2    Goring, H.H.3    Lindroos, K.4    Wiman, A.C.5    Sturfelt, G.6
  • 176
    • 84856007704 scopus 로고    scopus 로고
    • Cardiovascular and neurological causes of sudden death after ischaemic stroke
    • Soros P, Hachinski V, (2012). Cardiovascular and neurological causes of sudden death after ischaemic stroke. Lancet Neurol 11: 179-188.
    • (2012) Lancet Neurol , vol.11 , pp. 179-188
    • Soros, P.1    Hachinski, V.2
  • 177
    • 79954571076 scopus 로고    scopus 로고
    • Therapeutic targets for neuroprotection in acute ischemic stroke: Lost in translation?
    • Stankowski JN, Gupta R, (2011). Therapeutic targets for neuroprotection in acute ischemic stroke: lost in translation? Antioxid Redox Signal 14: 1841-1851.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 1841-1851
    • Stankowski, J.N.1    Gupta, R.2
  • 178
    • 79958248587 scopus 로고    scopus 로고
    • Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury
    • Stevens SL, Leung PY, Vartanian KB, Gopalan B, Yang T, Simon RP, et al. (2011). Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury. J Neurosci 31: 8456-8463.
    • (2011) J Neurosci , vol.31 , pp. 8456-8463
    • Stevens, S.L.1    Leung, P.Y.2    Vartanian, K.B.3    Gopalan, B.4    Yang, T.5    Simon, R.P.6
  • 179
    • 33646377870 scopus 로고    scopus 로고
    • Interferon signalling network in innate defence
    • Takaoka A, Yanai H, (2006). Interferon signalling network in innate defence. Cell Microbiol 8: 907-922.
    • (2006) Cell Microbiol , vol.8 , pp. 907-922
    • Takaoka, A.1    Yanai, H.2
  • 180
    • 0742324860 scopus 로고    scopus 로고
    • TLR signaling pathways
    • Takeda K, Akira S, (2004). TLR signaling pathways. Semin Immunol 16: 3-9.
    • (2004) Semin Immunol , vol.16 , pp. 3-9
    • Takeda, K.1    Akira, S.2
  • 181
    • 18644382503 scopus 로고    scopus 로고
    • IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells
    • Taki S, Nakajima S, Ichikawa E, Saito T, Hida S, (2005). IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells. J Immunol 174: 6005-6012.
    • (2005) J Immunol , vol.174 , pp. 6005-6012
    • Taki, S.1    Nakajima, S.2    Ichikawa, E.3    Saito, T.4    Hida, S.5
  • 182
    • 0036178254 scopus 로고    scopus 로고
    • ICSBP/IRF-8: Its regulatory roles in the development of myeloid cells
    • Tamura T, Ozato K, (2002). ICSBP/IRF-8: its regulatory roles in the development of myeloid cells. J Interferon Cytokine Res 22: 145-152.
    • (2002) J Interferon Cytokine Res , vol.22 , pp. 145-152
    • Tamura, T.1    Ozato, K.2
  • 183
    • 14044270784 scopus 로고    scopus 로고
    • IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity
    • Tamura T, Tailor P, Yamaoka K, Kong HJ, Tsujimura H, O'Shea JJ, et al. (2005). IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. J Immunol 174: 2573-2581.
    • (2005) J Immunol , vol.174 , pp. 2573-2581
    • Tamura, T.1    Tailor, P.2    Yamaoka, K.3    Kong, H.J.4    Tsujimura, H.5    O'Shea, J.J.6
  • 184
    • 42649114059 scopus 로고    scopus 로고
    • The IRF family transcription factors in immunity and oncogenesis
    • Tamura T, Yanai H, Savitsky D, Taniguchi T, (2008). The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol 26: 535-584.
    • (2008) Annu Rev Immunol , vol.26 , pp. 535-584
    • Tamura, T.1    Yanai, H.2    Savitsky, D.3    Taniguchi, T.4
  • 185
    • 0027250364 scopus 로고
    • Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system
    • Tanaka N, Kawakami T, Taniguchi T, (1993). Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system. Mol Cell Biol 13: 4531-4538.
    • (1993) Mol Cell Biol , vol.13 , pp. 4531-4538
    • Tanaka, N.1    Kawakami, T.2    Taniguchi, T.3
  • 186
    • 35348860696 scopus 로고    scopus 로고
    • Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
    • Tang SC, Arumugam TV, Xu X, Cheng A, Mughal MR, Jo DG, et al. (2007a). Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc Natl Acad Sci U S A 104: 13798-13803.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13798-13803
    • Tang, S.C.1    Arumugam, T.V.2    Xu, X.3    Cheng, A.4    Mughal, M.R.5    Jo, D.G.6
  • 187
    • 34848817968 scopus 로고    scopus 로고
    • Acetylation-dependent signal transduction for type i interferon receptor
    • Tang X, Gao JS, Guan YJ, McLane KE, Yuan ZL, Ramratnam B, et al. (2007b). Acetylation-dependent signal transduction for type I interferon receptor. Cell 131: 93-105.
    • (2007) Cell , vol.131 , pp. 93-105
    • Tang, X.1    Gao, J.S.2    Guan, Y.J.3    McLane, K.E.4    Yuan, Z.L.5    Ramratnam, B.6
  • 188
    • 0036467492 scopus 로고    scopus 로고
    • The interferon-alpha/beta system in antiviral responses: A multimodal machinery of gene regulation by the IRF family of transcription factors
    • Taniguchi T, Takaoka A, (2002). The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors. Curr Opin Immunol 14: 111-116.
    • (2002) Curr Opin Immunol , vol.14 , pp. 111-116
    • Taniguchi, T.1    Takaoka, A.2
  • 189
    • 0035061538 scopus 로고    scopus 로고
    • IRF family of transcription factors as regulators of host defense
    • Taniguchi T, Ogasawara K, Takaoka A, Tanaka N, (2001). IRF family of transcription factors as regulators of host defense. Annu Rev Immunol 19: 623-655.
    • (2001) Annu Rev Immunol , vol.19 , pp. 623-655
    • Taniguchi, T.1    Ogasawara, K.2    Takaoka, A.3    Tanaka, N.4
  • 190
    • 41149165830 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction
    • Timmers L, Sluijter JP, van Keulen JK, Hoefer IE, Nederhoff MG, Goumans MJ, et al. (2008). Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction. Circ Res 102: 257-264.
    • (2008) Circ Res , vol.102 , pp. 257-264
    • Timmers, L.1    Sluijter, J.P.2    Van Keulen, J.K.3    Hoefer, I.E.4    Nederhoff, M.G.5    Goumans, M.J.6
  • 191
    • 79955653358 scopus 로고    scopus 로고
    • IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension
    • Tsushima K, Osawa T, Yanai H, Nakajima A, Takaoka A, Manabe I, et al. (2011). IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension. FASEB J 25: 1531-1543.
    • (2011) FASEB J , vol.25 , pp. 1531-1543
    • Tsushima, K.1    Osawa, T.2    Yanai, H.3    Nakajima, A.4    Takaoka, A.5    Manabe, I.6
  • 194
    • 0037079695 scopus 로고    scopus 로고
    • Cytokine-inducible CD40 expression in human endothelial cells is mediated by interferon regulatory factor-1
    • Wagner AH, Gebauer M, Pollok-Kopp B, Hecker M, (2002). Cytokine-inducible CD40 expression in human endothelial cells is mediated by interferon regulatory factor-1. Blood 99: 520-525.
    • (2002) Blood , vol.99 , pp. 520-525
    • Wagner, A.H.1    Gebauer, M.2    Pollok-Kopp, B.3    Hecker, M.4
  • 195
    • 11144324185 scopus 로고    scopus 로고
    • Disruption of Erk-dependent type i interferon induction breaks the myxoma virus species barrier
    • Wang F, Ma Y, Barrett JW, Gao X, Loh J, Barton E, et al. (2004). Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier. Nat Immunol 5: 1266-1274.
    • (2004) Nat Immunol , vol.5 , pp. 1266-1274
    • Wang, F.1    Ma, Y.2    Barrett, J.W.3    Gao, X.4    Loh, J.5    Barton, E.6
  • 196
    • 66549125977 scopus 로고    scopus 로고
    • IRF8 regulates myeloid and B lymphoid lineage diversification
    • Wang H, Morse HC 3rd, (2009). IRF8 regulates myeloid and B lymphoid lineage diversification. Immunol Res 43: 109-117.
    • (2009) Immunol Res , vol.43 , pp. 109-117
    • Wang, H.1    Morse, H.C.2
  • 197
    • 58149148414 scopus 로고    scopus 로고
    • IRF8 regulates B-cell lineage specification, commitment, and differentiation
    • Wang H, Lee CH, Qi C, Tailor P, Feng J, Abbasi S, et al. (2008). IRF8 regulates B-cell lineage specification, commitment, and differentiation. Blood 112: 4028-4038.
    • (2008) Blood , vol.112 , pp. 4028-4038
    • Wang, H.1    Lee, C.H.2    Qi, C.3    Tailor, P.4    Feng, J.5    Abbasi, S.6
  • 198
    • 34250011799 scopus 로고    scopus 로고
    • The ubiquitin-proteasome system and its role in inflammatory and autoimmune diseases
    • Wang J, Maldonado MA, (2006). The ubiquitin-proteasome system and its role in inflammatory and autoimmune diseases. Cell Mol Immunol 3: 255-261.
    • (2006) Cell Mol Immunol , vol.3 , pp. 255-261
    • Wang, J.1    Maldonado, M.A.2
  • 199
    • 84884275991 scopus 로고    scopus 로고
    • Negative regulation of Nmi on virus-triggered type i IFN production by targeting IRF7
    • Wang J, Yang B, Hu Y, Zheng Y, Zhou H, Wang Y, et al. (2013a). Negative regulation of Nmi on virus-triggered type I IFN production by targeting IRF7. J Immunol 191: 3393-3399.
    • (2013) J Immunol , vol.191 , pp. 3393-3399
    • Wang, J.1    Yang, B.2    Hu, Y.3    Zheng, Y.4    Zhou, H.5    Wang, Y.6
  • 200
    • 84864120317 scopus 로고    scopus 로고
    • SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress
    • Wang L, Lu Y, Deng S, Zhang Y, Yang L, Guan Y, et al. (2012). SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress. J Neurochem 122: 834-843.
    • (2012) J Neurochem , vol.122 , pp. 834-843
    • Wang, L.1    Lu, Y.2    Deng, S.3    Zhang, Y.4    Yang, L.5    Guan, Y.6
  • 201
    • 84881370740 scopus 로고    scopus 로고
    • Mindin is a critical mediator of ischemic brain injury in an experimental stroke model
    • Wang L, Lu Y, Zhang X, Zhang Y, Jiang D, Dong X, et al. (2013b). Mindin is a critical mediator of ischemic brain injury in an experimental stroke model. Exp Neurol 247: 506-516.
    • (2013) Exp Neurol , vol.247 , pp. 506-516
    • Wang, L.1    Lu, Y.2    Zhang, X.3    Zhang, Y.4    Jiang, D.5    Dong, X.6
  • 202
    • 84881030779 scopus 로고    scopus 로고
    • Interferon regulatory factor 9 protects against hepatic insulin resistance and steatosis in male mice
    • Wang XA, Zhang R, Jiang D, Deng W, Zhang S, Deng S, et al. (2013c). Interferon regulatory factor 9 protects against hepatic insulin resistance and steatosis in male mice. Hepatology 58: 603-616.
    • (2013) Hepatology , vol.58 , pp. 603-616
    • Wang, X.A.1    Zhang, R.2    Jiang, D.3    Deng, W.4    Zhang, S.5    Deng, S.6
  • 203
    • 84896696454 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 constrains IKKbeta/NF-kappaB signaling to alleviate hepatic steatosis and insulin resistance
    • Wang XA, Zhang R, She ZG, Zhang XF, Jiang DS, Wang T, et al. (2014). Interferon regulatory factor 3 constrains IKKbeta/NF-kappaB signaling to alleviate hepatic steatosis and insulin resistance. Hepatology 59: 870-885.
    • (2014) Hepatology , vol.59 , pp. 870-885
    • Wang, X.A.1    Zhang, R.2    She, Z.G.3    Zhang, X.F.4    Jiang, D.S.5    Wang, T.6
  • 204
    • 84881642190 scopus 로고    scopus 로고
    • Interferon regulatory factor 7 deficiency prevents diet-induced obesity and insulin resistance
    • Wang XA, Zhang R, Zhang S, Deng S, Jiang D, Zhong J, et al. (2013d). Interferon regulatory factor 7 deficiency prevents diet-induced obesity and insulin resistance. Am J Physiol Endocrinol Metab 305: E485-E495.
    • (2013) Am J Physiol Endocrinol Metab , vol.305 , pp. E485-E495
    • Wang, X.A.1    Zhang, R.2    Zhang, S.3    Deng, S.4    Jiang, D.5    Zhong, J.6
  • 206
    • 0037439418 scopus 로고    scopus 로고
    • A central role of interferon regulatory factor-1 for the limitation of neointimal hyperplasia
    • Wessely R, Hengst L, Jaschke B, Wegener F, Richter T, Lupetti R, et al. (2003). A central role of interferon regulatory factor-1 for the limitation of neointimal hyperplasia. Hum Mol Genet 12: 177-187.
    • (2003) Hum Mol Genet , vol.12 , pp. 177-187
    • Wessely, R.1    Hengst, L.2    Jaschke, B.3    Wegener, F.4    Richter, T.5    Lupetti, R.6
  • 207
    • 0141459384 scopus 로고    scopus 로고
    • Role for nuclear factor-kappaB and signal transducer and activator of transcription 1/interferon regulatory factor-1 in cytokine-induced endothelin-1 release in human vascular smooth muscle cells
    • Woods M, Wood EG, Bardswell SC, Bishop-Bailey D, Barker S, Wort SJ, et al. (2003). Role for nuclear factor-kappaB and signal transducer and activator of transcription 1/interferon regulatory factor-1 in cytokine-induced endothelin-1 release in human vascular smooth muscle cells. Mol Pharmacol 64: 923-931.
    • (2003) Mol Pharmacol , vol.64 , pp. 923-931
    • Woods, M.1    Wood, E.G.2    Bardswell, S.C.3    Bishop-Bailey, D.4    Barker, S.5    Wort, S.J.6
  • 208
    • 84902375462 scopus 로고    scopus 로고
    • Interferon regulatory factor 8 protects against cerebral ischaemic-reperfusion injury
    • Xiang M, Wang L, Guo S, Lu YY, Lei H, Jiang DS, et al. (2014). Interferon regulatory factor 8 protects against cerebral ischaemic-reperfusion injury. J Neurochem 129: 988-1001.
    • (2014) J Neurochem , vol.129 , pp. 988-1001
    • Xiang, M.1    Wang, L.2    Guo, S.3    Lu, Y.Y.4    Lei, H.5    Jiang, D.S.6
  • 209
    • 84255191988 scopus 로고    scopus 로고
    • Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction
    • Xiao J, Moon M, Yan L, Nian M, Zhang Y, Liu C, et al. (2012). Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction. Basic Res Cardiol 107: 239.
    • (2012) Basic Res Cardiol , vol.107 , pp. 239
    • Xiao, J.1    Moon, M.2    Yan, L.3    Nian, M.4    Zhang, Y.5    Liu, C.6
  • 210
    • 21244458133 scopus 로고    scopus 로고
    • Ubiquitin-dependent degradation of interferon regulatory factor-8 mediated by Cbl down-regulates interleukin-12 expression
    • Xiong H, Li H, Kong HJ, Chen Y, Zhao J, Xiong S, et al. (2005). Ubiquitin-dependent degradation of interferon regulatory factor-8 mediated by Cbl down-regulates interleukin-12 expression. J Biol Chem 280: 23531-23539.
    • (2005) J Biol Chem , vol.280 , pp. 23531-23539
    • Xiong, H.1    Li, H.2    Kong, H.J.3    Chen, Y.4    Zhao, J.5    Xiong, S.6
  • 212
    • 80053926066 scopus 로고    scopus 로고
    • Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development
    • Yamamoto M, Kato T, Hotta C, Nishiyama A, Kurotaki D, Yoshinari M, et al. (2011). Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development. PLoS ONE 6: e25812.
    • (2011) PLoS ONE , vol.6 , pp. e25812
    • Yamamoto, M.1    Kato, T.2    Hotta, C.3    Nishiyama, A.4    Kurotaki, D.5    Yoshinari, M.6
  • 213
    • 80052877375 scopus 로고    scopus 로고
    • Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3beta and TGF-beta1-SMAD signalling
    • Yan L, Wei X, Tang QZ, Feng J, Zhang Y, Liu C, et al. (2011). Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3beta and TGF-beta1-SMAD signalling. Cardiovasc Res 92: 85-94.
    • (2011) Cardiovasc Res , vol.92 , pp. 85-94
    • Yan, L.1    Wei, X.2    Tang, Q.Z.3    Feng, J.4    Zhang, Y.5    Liu, C.6
  • 214
    • 84877656613 scopus 로고    scopus 로고
    • The IRF family of transcription factors: Inception, impact and implications in oncogenesis
    • Yanai H, Negishi H, Taniguchi T, (2012). The IRF family of transcription factors: inception, impact and implications in oncogenesis. Oncoimmunology 1: 1376-1386.
    • (2012) Oncoimmunology , vol.1 , pp. 1376-1386
    • Yanai, H.1    Negishi, H.2    Taniguchi, T.3
  • 215
    • 80555154915 scopus 로고    scopus 로고
    • Cutting edge: IRF8 regulates Bax transcription in vivo in primary myeloid cells
    • Yang J, Hu X, Zimmerman M, Torres CM, Yang D, Smith SB, et al. (2011). Cutting edge: IRF8 regulates Bax transcription in vivo in primary myeloid cells. J Immunol 187: 4426-4430.
    • (2011) J Immunol , vol.187 , pp. 4426-4430
    • Yang, J.1    Hu, X.2    Zimmerman, M.3    Torres, C.M.4    Yang, D.5    Smith, S.B.6
  • 216
    • 65449153592 scopus 로고    scopus 로고
    • TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response
    • Yang K, Shi HX, Liu XY, Shan YF, Wei B, Chen S, et al. (2009). TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response. J Immunol 182: 3782-3792.
    • (2009) J Immunol , vol.182 , pp. 3782-3792
    • Yang, K.1    Shi, H.X.2    Liu, X.Y.3    Shan, Y.F.4    Wei, B.5    Chen, S.6
  • 217
    • 84866556348 scopus 로고    scopus 로고
    • Monocytes from Irf5-/- mice have an intrinsic defect in their response to pristane-induced lupus
    • Yang L, Feng D, Bi X, Stone RC, Barnes BJ, (2012). Monocytes from Irf5-/- mice have an intrinsic defect in their response to pristane-induced lupus. J Immunol 189: 3741-3750.
    • (2012) J Immunol , vol.189 , pp. 3741-3750
    • Yang, L.1    Feng, D.2    Bi, X.3    Stone, R.C.4    Barnes, B.J.5
  • 218
    • 23844438864 scopus 로고    scopus 로고
    • Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
    • Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, et al. (2005). Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 175: 2851-2858.
    • (2005) J Immunol , vol.175 , pp. 2851-2858
    • Yoneyama, M.1    Kikuchi, M.2    Matsumoto, K.3    Imaizumi, T.4    Miyagishi, M.5    Taira, K.6
  • 219
    • 0037968290 scopus 로고    scopus 로고
    • Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes
    • Yoshida T, Sinha S, Dandre F, Wamhoff BR, Hoofnagle MH, Kremer BE, et al. (2003). Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes. Circ Res 92: 856-864.
    • (2003) Circ Res , vol.92 , pp. 856-864
    • Yoshida, T.1    Sinha, S.2    Dandre, F.3    Wamhoff, B.R.4    Hoofnagle, M.H.5    Kremer, B.E.6
  • 220
    • 55549146091 scopus 로고    scopus 로고
    • Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3
    • Zhang M, Tian Y, Wang RP, Gao D, Zhang Y, Diao FC, et al. (2008). Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3. Cell Res 18: 1096-1104.
    • (2008) Cell Res , vol.18 , pp. 1096-1104
    • Zhang, M.1    Tian, Y.2    Wang, R.P.3    Gao, D.4    Zhang, Y.5    Diao, F.C.6
  • 221
    • 84892455339 scopus 로고    scopus 로고
    • Interferon regulatory factor 8 modulates phenotypic switching of smooth muscle cells by regulating the activity of myocardin
    • Zhang SM, Gao L, Zhang XF, Zhang R, Zhu LH, Wang PX, et al. (2014a). Interferon regulatory factor 8 modulates phenotypic switching of smooth muscle cells by regulating the activity of myocardin. Mol Cell Biol 34: 400-414.
    • (2014) Mol Cell Biol , vol.34 , pp. 400-414
    • Zhang, S.M.1    Gao, L.2    Zhang, X.F.3    Zhang, R.4    Zhu, L.H.5    Wang, P.X.6
  • 222
    • 84901401528 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 protects against adverse neo-intima formation
    • Zhang SM, Zhu LH, Li ZZ, Wang PX, Chen HZ, Guan HJ, et al. (2014b). Interferon regulatory factor 3 protects against adverse neo-intima formation. Cardiovasc Res 102: 469-479.
    • (2014) Cardiovasc Res , vol.102 , pp. 469-479
    • Zhang, S.M.1    Zhu, L.H.2    Li, Z.Z.3    Wang, P.X.4    Chen, H.Z.5    Guan, H.J.6
  • 223
    • 84906159752 scopus 로고    scopus 로고
    • Interferon regulatory factor 9 is an essential mediator of heart dysfunction and cell death following myocardial ischemia/reperfusion injury
    • Zhang Y, Liu X, She ZG, Jiang DS, Wan N, Xia H, et al. (2014c). Interferon regulatory factor 9 is an essential mediator of heart dysfunction and cell death following myocardial ischemia/reperfusion injury. Basic Res Cardiol 109: 434.
    • (2014) Basic Res Cardiol , vol.109 , pp. 434
    • Zhang, Y.1    Liu, X.2    She, Z.G.3    Jiang, D.S.4    Wan, N.5    Xia, H.6
  • 225
    • 84919795881 scopus 로고    scopus 로고
    • Interferon regulatory factors: At the crossroads of immunity, metabolism, and disease
    • [Epub ahead of print]
    • Zhao GN, Jiang DS, Li H, (2014). Interferon regulatory factors: at the crossroads of immunity, metabolism, and disease. Biochim Biophys Acta doi: 10.1016/j.bbadis.2014.04.030. [Epub ahead of print].
    • (2014) Biochim Biophys Acta
    • Zhao, G.N.1    Jiang, D.S.2    Li, H.3
  • 226
    • 65349172388 scopus 로고    scopus 로고
    • Transcriptional regulatory networks in Th17 cell differentiation
    • Zhou L, Littman DR, (2009). Transcriptional regulatory networks in Th17 cell differentiation. Curr Opin Immunol 21: 146-152.
    • (2009) Curr Opin Immunol , vol.21 , pp. 146-152
    • Zhou, L.1    Littman, D.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.