메뉴 건너뛰기




Volumn 14, Issue 10, 2011, Pages 1841-1851

Therapeutic targets for neuroprotection in acute ischemic stroke: Lost in translation?

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINO 5 (2,3,5 TRICHLOROPHENYL)PYRIMIDINE; AMPA RECEPTOR; BILOBALIDE; CASPASE INHIBITOR; FIBRINOLYTIC AGENT; LAMOTRIGINE; LIDOCAINE; N [4 [4 [(3,4 DIHYDRO 6 HYDROXY 2,5,7,8 TETRAMETHYL 2H 1 BENZOPYRAN 2 YL)CARBONYL] 1 PIPERAZINYL]PHENYL] 2 THIOPHENECARBOXIMIDAMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; REACTIVE OXYGEN METABOLITE; SIPATRIGINE; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN; TISSUE PLASMINOGEN ACTIVATOR;

EID: 79954571076     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2010.3292     Document Type: Review
Times cited : (66)

References (66)
  • 2
    • 0035105629 scopus 로고    scopus 로고
    • Perfusion thresholds in human cerebral ischemia: Historical perspective and therapeutic implications
    • Baron JC. Perfusion thresholds in human cerebral ischemia: Historical perspective and therapeutic implications. Cerbrovasc Dis 11: 2-08, 2001.
    • (2001) Cerbrovasc Dis , vol.11 , pp. 2-08
    • Baron, J.C.1
  • 3
    • 0035182221 scopus 로고    scopus 로고
    • Stress management - Heat shock protein-70 and the regulation of apoptosis
    • DOI 10.1016/S0962-8924(00)01874-2, PII S0962892400018742
    • Beere H and Green DR. Stress management-heat shock protein-70 and the regulation of apoptosis. Trends Cell Biol 11: 6-10, 2001. (Pubitemid 32056181)
    • (2001) Trends in Cell Biology , vol.11 , Issue.1 , pp. 6-10
    • Beere, H.M.1    Green, D.R.2
  • 4
    • 3242879188 scopus 로고    scopus 로고
    • 'The stress of dying': The role of heat shock proteins in the regulation of apoptosis
    • DOI 10.1242/jcs.01284
    • Beere H. The stress of dying: The role of heat shock proteins in the regulation of apoptosis. J Cell Sci 117: 2641-2651, 2004. (Pubitemid 38997248)
    • (2004) Journal of Cell Science , vol.117 , Issue.13 , pp. 2641-2651
    • Beere, H.M.1
  • 5
    • 26444495615 scopus 로고    scopus 로고
    • Death versus survival: Functional interaction between the apoptotic and stress-inducible heat shock protein pathways
    • DOI 10.1172/JCI26471
    • Beere HM. Death versus survival: Functional interaction between apoptotic and stress-inducible heat shock protein pathways. J Clin Invest 115: 2633-2639, 2005. (Pubitemid 41434386)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2633-2639
    • Beere, H.M.1
  • 9
    • 77951206114 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 (MMP-9) expression and extracellular signal-regulated kinase 1 and 2 (ERK1=2) activation in exercise-reduced neuronal apoptosis after stroke
    • Chaudhry K, Rogers R, Gui M, Lai Q, Goel G, Liebelt B, Ji X, Curry A, Carranza A, Jimenez DF, and Ding Y. Matrix metalloproteinase-9 (MMP-9) expression and extracellular signal-regulated kinase 1 and 2 (ERK1=2) activation in exercise-reduced neuronal apoptosis after stroke. Neurosci Lett 474:109-114, 2010.
    • (2010) Neurosci Lett , vol.474 , pp. 109-114
    • Chaudhry, K.1    Rogers, R.2    Gui, M.3    Lai, Q.4    Goel, G.5    Liebelt, B.6    Ji, X.7    Curry, A.8    Carranza, A.9    Jimenez, D.F.10    Ding, Y.11
  • 10
    • 70349659449 scopus 로고    scopus 로고
    • Pharmacologic interventions for stroke: Looking beyond the thrombolysis time window into the penumbra with biomarkers, not a stopwatch
    • Chavez JC, Hurko O, Barone FC, and Feuerstein GZ. Pharmacologic interventions for stroke: Looking beyond the thrombolysis time window into the penumbra with biomarkers, not a stopwatch. Stroke 40: e558-e563, 2009.
    • (2009) Stroke , vol.40
    • Chavez, J.C.1    Hurko, O.2    Barone, F.C.3    Feuerstein, G.Z.4
  • 11
    • 0027196609 scopus 로고
    • Temperature modulation of cerebral depolarization during focal cerebral ischemia in rats: Correlation with ischemic injury
    • Chen Q, Chopp M, Bodzin G, and Chen H. Temperature modulation of cerebral depolarization during focal cerebral ischemia in rats: Correlation with ischemic injury. J Cereb Blood Flow Metab 13: 389-394, 1993. (Pubitemid 23129391)
    • (1993) Journal of Cerebral Blood Flow and Metabolism , vol.13 , Issue.3 , pp. 389-394
    • Chen, Q.1    Chopp, M.2    Bodzin, G.3    Chen, H.4
  • 12
    • 0342618284 scopus 로고    scopus 로고
    • Lamotrigine protects hippocampal CA1 neurons from ischemic damage after cardiac arrest
    • Crumrine RC, Bergstrand K, Cooper AT, Faison WL, and Cooper BR. Lamotrigine protects hippocampal CA1 neurons from ischemic damage after cardiac arrest. Stroke 28: 2230-2237, 1997. (Pubitemid 27497928)
    • (1997) Stroke , vol.28 , Issue.11 , pp. 2230-2237
    • Crumrine, R.C.1    Bergstrand, K.2    Cooper, A.T.3    Faison, W.L.4    Cooper, B.R.5
  • 13
    • 76849083790 scopus 로고    scopus 로고
    • 5-year clinical outcomes in the ICTUS (Invasive versus conservative treatment in unstable coronary syndromes) Trial: A randomized comparison of an early invasive versus selective invasive management in patients with non-ST-segment elevation acute coronary syndrome
    • ICTUS Investigators
    • Damman P, Hirsch A, Windhausen F, Tijssen JGP, De Winter RJ, and ICTUS Investigators. 5-year clinical outcomes in the ICTUS (Invasive versus conservative treatment in unstable coronary syndromes) Trial: A randomized comparison of an early invasive versus selective invasive management in patients with non-ST-segment elevation acute coronary syndrome. JACC 55: 858-864, 2010.
    • (2010) JACC , vol.55 , pp. 858-864
    • Damman, P.1    Hirsch, A.2    Windhausen, F.3    Jgp, T.4    De Winter, R.J.5
  • 14
    • 42649144101 scopus 로고    scopus 로고
    • Oxidative and nitrative protein modifications in Parkinson's disease
    • Danielson SR and Andersen JK. Oxidative and nitrative protein modifications in Parkinson's disease. Free Radic Biol Med 44: 1787-1794, 2008.
    • (2008) Free Radic Biol Med , vol.44 , pp. 1787-1794
    • Danielson, S.R.1    Andersen, J.K.2
  • 16
    • 0033766740 scopus 로고    scopus 로고
    • Lubeluzole in acute ischemic stroke treatment. A doubleblind study with an 8-hour inclusion window comparing a 10-mg daily dose of lubeluzole with placebo
    • for the LUB-INT-13 Investigators
    • Diener HC, Cortens M, Ford G, Grotta J, Hacke W, Kaste M, Koudstaal PJ, Wessel T, for the LUB-INT-13 Investigators. Lubeluzole in acute ischemic stroke treatment. A doubleblind study with an 8-hour inclusion window comparing a 10-mg daily dose of lubeluzole with placebo. Stroke 31: 2543-2551, 2000.
    • (2000) Stroke , vol.31 , pp. 2543-2551
    • Diener, H.C.1    Cortens, M.2    Ford, G.3    Grotta, J.4    Hacke, W.5    Kaste, M.6    Koudstaal, P.J.7    Wessel, T.8
  • 19
    • 0028217760 scopus 로고
    • Ions and energy in mammalian brain
    • DOI 10.1016/0301-0082(94)90015-9
    • Erecinska M and Silver IA. Ions and energy in mammalian brain. Prog Neurobiol 43: 37-71, 1994. (Pubitemid 24221854)
    • (1994) Progress in Neurobiology , vol.43 , Issue.1 , pp. 37-71
    • Erecinska, M.1    Silver, I.A.2
  • 20
    • 33244462144 scopus 로고    scopus 로고
    • Cortical spreading depression and peri-infarct depolarization in acutely injured human cerebral cortex
    • DOI 10.1093/brain/awh716
    • Fabricius M, Fuhr S, Buatia R, Boutelle M, Hashemi P, Strong AJ, and Lauritzen M. Cortical spreading depression and peri-infarct depolarization in acutely injured human cerebral cortex. Brain 129: 778-790, 2006. (Pubitemid 43278239)
    • (2006) Brain , vol.129 , Issue.3 , pp. 778-790
    • Fabricius, M.1    Fuhr, S.2    Bhatia, R.3    Boutelle, M.4    Hashemi, P.5    Strong, A.J.6    Lauritzen, M.7
  • 21
    • 0036215523 scopus 로고    scopus 로고
    • The stroke patient who woke up clinical and radiological features, including diffusion and perfusion MRI
    • DOI 10.1161/01.STR.0000014585.17714.67
    • Fink JN, Kumar S, Horkan C, Linfante I, Selim MH, Caplan LR, and Schlaug G. The stroke patient who woke up: Clinical and radiological features, including diffusion and perfusion MRI. Stroke 33: 988-993, 2002. (Pubitemid 34293580)
    • (2002) Stroke , vol.33 , Issue.4 , pp. 988-993
    • Fink, J.N.1    Kumar, S.2    Horkan, C.3    Linfante, I.4    Selim, M.H.5    Caplan, L.R.6    Schlaug, G.7
  • 22
    • 0027966070 scopus 로고
    • Lidocaine protects hippocampal neurons against ischemic damage by preventing increase of extracellular excitatory amino acids: A microdialysis study in Mongolian gerbils
    • Fujitani T, Adachi N, Miyazaki H, Liu K, Nakamura Y, Kataoka K, and Arai T. Lidocaine protects hippocampal neurons against ischemic damage by preventing increase of extracellular excitatory amino acids: A microdialysis study in Mongolian gerbils. Neurosci Lett 179: 91-93, 1994.
    • (1994) Neurosci Lett , vol.179 , pp. 91-93
    • Fujitani, T.1    Adachi, N.2    Miyazaki, H.3    Liu, K.4    Nakamura, Y.5    Kataoka, K.6    Arai, T.7
  • 23
    • 67949103567 scopus 로고    scopus 로고
    • Combination therapy with normobaric oxygen (NBO) plus thrombolysis in experimental ischemic stroke
    • Fujiwara N, Murata Y, Arai K, Egi Y, Lu J, Wu O, Singhal AB, and Lo EH. Combination therapy with normobaric oxygen (NBO) plus thrombolysis in experimental ischemic stroke. BMC Neurosci 10: 79-87, 2009.
    • (2009) BMC Neurosci , vol.10 , pp. 79-87
    • Fujiwara, N.1    Murata, Y.2    Arai, K.3    Egi, Y.4    Lu, J.5    Wu, O.6    Singhal, A.B.7    Lo, E.H.8
  • 24
    • 0036262303 scopus 로고    scopus 로고
    • Antioxidant therapy in acute central nervous system injury: Current state
    • DOI 10.1124/pr.54.2.271
    • Gilgun-Sherki Y, Rosenbaum Z, Melamed E, and Offen D. Antioxidant therapy in acute central nervous system injury: Current state. Pharmacol Rev 54: 271-284, 2002. (Pubitemid 34575717)
    • (2002) Pharmacological Reviews , vol.54 , Issue.2 , pp. 271-284
    • Gilgun-Sherki, Y.1    Rosenbaum, Z.2    Melamed, E.3    Offen, D.4
  • 26
    • 0028362182 scopus 로고
    • Neuroprotective effects of a use-dependent blocker of voltage dependent sodium channels, BW619C89, in rat middle cerebral artery occlusion
    • Graham SH, Chen J, Lan J, Leach MJ, and Simon RP. Neuroprotective effects of a use-dependent blocker of voltage-dependent sodium channels, BW619C89 in rat middle cerebral artery occlusion. JPET 269: 854-859, 1994. (Pubitemid 24157361)
    • (1994) Journal of Pharmacology and Experimental Therapeutics , vol.269 , Issue.2 , pp. 854-859
    • Graham, S.H.1    Chen, J.2    Lan, J.3    Leach, M.J.4    Simon, R.P.5
  • 27
    • 62449268980 scopus 로고    scopus 로고
    • Molecular simulations elucidate the substrate translocation pathway in a glutamate transporter
    • Gu Y, Shrivastava IH, Amara SG, and Bahar I. Molecular simulations elucidate the substrate translocation pathway in a glutamate transporter. Proc Natl Acad Sci USA 106: 2589-2594, 2009.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 2589-2594
    • Gu, Y.1    Shrivastava, I.H.2    Amara, S.G.3    Bahar, I.4
  • 28
    • 40749149164 scopus 로고    scopus 로고
    • Effect of endovascular hypothermia on acute ischemic edema: Morphometric analysis of the ICTuS trial
    • DOI 10.1007/s12028-007-9009-z
    • Guluma KZ, Oh H, Yu SW, Meyer BC, Rapp K, and Lyden PD. Effect of endovascular hypothermia on acute ischemic edema: Morphometric analysis of the ICTuS trial. Neruocrit Care 8: 42-47, 2008. (Pubitemid 351378106)
    • (2008) Neurocritical Care , vol.8 , Issue.1 , pp. 42-47
    • Guluma, K.Z.1    Oh, H.2    Yu, S.-W.3    Meyer, B.C.4    Rapp, K.5    Lyden, P.D.6
  • 29
    • 33749021333 scopus 로고    scopus 로고
    • Reduced pretreatment ipsilateral middle cerebral artery cerebral blood flow is predictive of symptomatic hemorrhage post-intra-arterial thrombolysis in patients with middle cerebral artery occlusion
    • DOI 10.1161/01.STR.0000240687.14265.b4, PII 0000767020061000000022
    • Gupta R, Yonas H, Gebel J, Goldstein S, Horowitz M, Grahovac SZ, Wechsler LR, Hammer MD, Uchino K, and Jovin TG. Reduced pretreatment ipislateral middle cerebral blood flow is predictive of symptomatic hemorrhage postintra-arterial thrombolysis in patients with middle cerebral artery occlusion. Stroke 37: 2526-2530, 2006. (Pubitemid 44454673)
    • (2006) Stroke , vol.37 , Issue.10 , pp. 2526-2530
    • Gupta, R.1    Yonas, H.2    Gebel, J.3    Goldstein, S.4    Horowitz, M.5    Grahovac, S.Z.6    Wechsler, L.R.7    Hammer, M.D.8    Uchino, K.9    Jovin, T.G.10
  • 32
    • 0035094866 scopus 로고    scopus 로고
    • Anoxic depolarization mediates acute damage independent of glutamate in neocortical brain slices
    • Jarvis CR, Anderson TR, and Andrew D. Anoxic depolarization mediates acute damage independent of glutamate in neocortical brain slices. Cereb Cortex 11: 249-259, 2001. (Pubitemid 32199645)
    • (2001) Cerebral Cortex , vol.11 , Issue.3 , pp. 249-259
    • Jarvis, C.R.1    Anderson, T.R.2    Andrew, R.D.3
  • 33
    • 0035175929 scopus 로고    scopus 로고
    • Imaging anoxic depolarization during ischemia-like conditions in the mouse hemi-brain slice
    • Joshi I and Andrew RD. Imaging anoxic depolarization during ischemia-like conditions in the mouse hemi-brain slice. J Neurophysiol 85: 414-424, 2001. (Pubitemid 32062152)
    • (2001) Journal of Neurophysiology , vol.85 , Issue.1 , pp. 414-424
    • Joshi, I.1    Andrew, R.D.2
  • 34
    • 0141754078 scopus 로고    scopus 로고
    • The cortical ischemic core and not the consistently present penumbra is a determinant of clinical outcome in acute middle cerebral artery occlusion
    • DOI 10.1161/01.STR.0000091232.81947.C9
    • Jovin TG, Yonas H, Gebel JM, Kanal E, Chang YF, Gahovac SZ, Goldstein S, and Wechsler LR. The cortical ischemic core and the consistently present penumbra is a determinant of clinical outcome in acute middle cerebral artery occlusion. Stroke 34: 2426-2433, 2003. (Pubitemid 37221955)
    • (2003) Stroke , vol.34 , Issue.10 , pp. 2426-2433
    • Jovin, T.G.1    Yonas, H.2    Gebel, J.M.3    Kanal, E.4    Chang, Y.F.5    Grahovac, S.Z.6    Goldstein, S.7    Wechsler, L.R.8
  • 35
    • 7644241715 scopus 로고    scopus 로고
    • Evolving paradigms in neuroimaging of the ischemic penumbra
    • Kidwell CS, Alger JR, and Saver JL. Evolving paradigms in neuroimaging of the ischemic penumbra. Stroke 35: 2662-2665, 2003.
    • (2003) Stroke , vol.35 , pp. 2662-2665
    • Kidwell, C.S.1    Alger, J.R.2    Saver, J.L.3
  • 36
    • 0034889655 scopus 로고    scopus 로고
    • Cooling for acute ischemic brain damage (COOL AID): An open pilot study of induced hypothermia in acute ischemic stroke
    • Krieger DW, DeGeorgia MA, Abou-Chebl A, Andrefsky JC, Sila CA, Katzan IL Mayberg MR, and Furlan AJ. Cooling for acute ischemic brain damage (COOL AID). An open pilot study of induced hypothermia in acute ischemic stroke. Stroke 32: 1847-1854, 2001. (Pubitemid 32772218)
    • (2001) Stroke , vol.32 , Issue.8 , pp. 1847-1854
    • Krieger, D.W.1    De Georgia, M.A.2    Abou-Chebl, A.3    Andrefsky, J.C.4    Sila, C.A.5    Katzan, I.L.6    Mayberg, M.R.7    Furlan, A.J.8
  • 37
    • 0037386075 scopus 로고    scopus 로고
    • Guidelines and recommendations for perfusion imaging in cerebral ischemia: A scientific statement for healthcare professionals by the Writing Group on Perfusion Imaging, from the Council on Cardiovascular Radiology of the American Heart Association
    • DOI 10.1161/01.STR.0000064840.99271.9E
    • Latchaw RE, Yonas H, Hunter GJ, Yuh WT, Ueda T, Sorensen AG, Sunshine JL, Biller J, Wechsler L, Higashida R, et al. Guidelines and recommendations for perfusion imaging in cerebral ischemia: A scientific statement for healthcare professionals by the writing group on perfusion imaging, from the Council on Cardiovascular Radiology of the American Heart Association. Stroke 34: 1084-1104, 2003. (Pubitemid 36402992)
    • (2003) Stroke , vol.34 , Issue.4 , pp. 1084-1104
    • Latchaw, R.E.1    Yonas, H.2    Hunter, G.J.3    Yuh, W.T.C.4    Ueda, T.5    Sorensen, A.G.6    Sunshine, J.L.7    Biller, J.8    Wechsler, L.9    Higashida, R.10    Hademenos, G.11
  • 38
    • 0027208558 scopus 로고
    • The pyrimidine-derivative, BW1003C87, protects CA1 and striatal neurons following transient severe forebrain ischaemia in rats. A microdialysis and histological study
    • DOI 10.1016/0306-4522(93)90565-W
    • Lekiefre D and Meldrum BS. The pyrimidine-derivative, BW 1003C87, protects CA1 and striatal neurons following transient severe forebrain ischaemia in rats. A microdialysis and histological study. Neuroscience 56: 93-99, 1993. (Pubitemid 23261807)
    • (1993) Neuroscience , vol.56 , Issue.1 , pp. 93-99
    • Lekieffre, D.1    Meldrum, B.S.2
  • 39
    • 42749091885 scopus 로고    scopus 로고
    • Hyperbaric oxygen preconditioning induces tolerance against brain ischemia-reperfusion injury by upregulation of antioxidant enzymes in rats
    • Li J, Liu W, Ding S, Xu W, Guan Y, Zhang JH, and Sun X. Hyperbaric oxygen preconditioning induces tolerance against brain ischemia-reperfusion injury by upregulation of antioxidant enzymes in rats. Brain Res 1210: 223-229, 2008.
    • (2008) Brain Res , vol.1210 , pp. 223-229
    • Li, J.1    Liu, W.2    Ding, S.3    Xu, W.4    Guan, Y.5    Zhang, J.H.6    Sun, X.7
  • 40
    • 0037321482 scopus 로고    scopus 로고
    • Vampire bat salivary plasminogen activator (desmoteplase): A unique fibrinolytic enzyme that does not promote neurodegeneration
    • DOI 10.1161/01.STR.0000049764.49162.76
    • Liberatore GT, Samson A, Bladin C, Schleuning WD, and Medcalf RL. Vampire bat salivary plasminogen activator (Desmoteplase). A unique fibrinolytic enzyme that does not promote neurodegeneration. Stroke 34: 537-543, 2003. (Pubitemid 36206361)
    • (2003) Stroke , vol.34 , Issue.2 , pp. 537-543
    • Liberatore, G.T.1    Samson, A.2    Bladin, C.3    Schleuning, W.-D.4    Medcalf, R.L.5
  • 42
    • 60449094498 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2009 update
    • A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Lloyd-Jones D, Adams R, Carnethon M, De Simone G, et al. Heart disease and stroke statistics-2009 update. A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 119: e21-e181, 2009.
    • (2009) Circulation , vol.119
    • Lloyd-Jones, D.1    Adams, R.2    Carnethon, M.3    De Simone, G.4
  • 43
    • 0029773397 scopus 로고    scopus 로고
    • An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat
    • Loddick SA, MacKenzie A, and Rothwell NJ. An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat. Neuroreport 7: 1465-1468, 1996. (Pubitemid 26281123)
    • (1996) NeuroReport , vol.7 , Issue.9 , pp. 1465-1468
    • Loddick, S.A.1    MacKenzie, A.2    Rothwell, N.J.3
  • 46
    • 0028091767 scopus 로고
    • + channel modulator and glutamate release inhibitor in cultured rat cerebellar neurons and in gerbil global brain ischemia
    • Lysko PG, Webb CL, Yue TL, Gu JL, and Feuerstein G. Neuroprotective effects of tetrodotoxin as a Na\+ channel modulator and glutamate release inhibitor in cultured rat cerebellar neurons and in gerbil global brain ischemia. Stroke 25: 2476-2482, 1994. (Pubitemid 24359322)
    • (1994) Stroke , vol.25 , Issue.12 , pp. 2476-2482
    • Lysko, P.G.1    Webb, C.L.2    Yue, T.-L.3    Gu, J.-L.4    Feuerstein, G.5
  • 47
  • 48
    • 33947628060 scopus 로고    scopus 로고
    • Molecular targets in cerebral ischemia for developing novel therapeutics
    • DOI 10.1016/j.brainresrev.2006.11.003, PII S0165017306001172
    • Mehta SL, Manhas N, and Raghubir R. Molecular targets in cerebral ischemia for developing novel therapeutics. Brain Res Rev 54: 34-66, 2007. (Pubitemid 46498164)
    • (2007) Brain Research Reviews , vol.54 , Issue.1 , pp. 34-66
    • Mehta, S.L.1    Manhas, N.2    Raghubir, R.3
  • 51
    • 17344384728 scopus 로고    scopus 로고
    • Molecular pathways in cerebral ischemia: Cues to novel therapeutic strategies
    • DOI 10.1385/MN:27:1:33
    • Onteniente B, Rasika S, Benchoua A, and Guegan C. Molecular pathways in cerebral ischemia. Cues to novel therapeutic strategies. Mol Neurobiol 27: 33-72, 2003. (Pubitemid 36515160)
    • (2003) Molecular Neurobiology , vol.27 , Issue.1 , pp. 33-72
    • Onteniente, B.1    Rasika, S.2    Benchoua, A.3    Guegan, C.4
  • 52
    • 0026452868 scopus 로고
    • Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats
    • Pellegrini-Giampietro DE, Zukin RS, Bennet MV, Cho S, and Pulsinelli WA. Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats. Proc Natl Acad Sci USA 89: 10499-10503, 1992.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10499-10503
    • Pellegrini-Giampietro, D.E.1    Zukin, R.S.2    Bennet, M.V.3    Cho, S.4    Pulsinelli, W.A.5
  • 53
    • 0034595540 scopus 로고    scopus 로고
    • μ-Calpain activation, DNA fragmentation, and synergistic effects of caspase and calpain inhibitors in protecting hippocampal neurons from ischemic damage
    • DOI 10.1016/S0006-8993(00)02301-5, PII S0006899300023015
    • Rami A, Agarwal R, Botez G, and Winckler J. m-Calpain activation, DNA fragmentation, and synergistic effects of caspase and calpain inhibitors in protecting hippocampal neurons from ischemic damage. Brain Res 866: 299-312, 2000. (Pubitemid 30313034)
    • (2000) Brain Research , vol.866 , Issue.1-2 , pp. 299-312
    • Rami, A.1    Agarwal, R.2    Botez, G.3    Winckler, J.4
  • 54
    • 33947511484 scopus 로고    scopus 로고
    • The impact of recanalization on ischemic stroke outcome: A meta-analysis
    • DOI 10.1161/01.STR.0000258112.14918.24, PII 0000767020070300000032
    • Rha JH and Saver JL. The impact of recanalization on ischemic stroke outcome: A meta-analysis. Stroke 38:967-973, 2007. (Pubitemid 46568460)
    • (2007) Stroke , vol.38 , Issue.3 , pp. 967-973
    • Rha, J.-H.1    Saver, J.L.2
  • 55
    • 0032449129 scopus 로고    scopus 로고
    • The family of sodium-dependent glutamate transporters: A focus on the GLT-1/EAAT2 subtype
    • PII S0197018698000552
    • Robinson MB. The family of sodium-dependent glutamate transporters: A focus on the GLT-1=EAAT2 subtype. Neurochem Int 33: 479-491, 1998. (Pubitemid 29116223)
    • (1998) Neurochemistry International , vol.33 , Issue.6 , pp. 479-491
    • Robinson, M.B.1
  • 56
    • 34249942190 scopus 로고    scopus 로고
    • Future of neuroprotection for acute stroke: In the aftermath of the SAINT trials
    • DOI 10.1002/ana.21127
    • Savitz SI and Fisher M. Future of neuroprotection for acute stroke: In the aftermath of the SAINT trials. Ann Neurol 61: 396-402, 2007. (Pubitemid 46878767)
    • (2007) Annals of Neurology , vol.61 , Issue.5 , pp. 396-402
    • Savitz, S.I.1    Fisher, M.2
  • 57
    • 33749643812 scopus 로고    scopus 로고
    • Oxygen therapy in stroke: Past, present, and future
    • DOI 10.1111/j.1747-4949.2006.00058.x
    • Singhal AB. Oxygen therapy in stroke: Past, present and future. Int J Stroke 1: 191-200, 2006. (Pubitemid 44541732)
    • (2006) International Journal of Stroke , vol.1 , Issue.4 , pp. 191-200
    • Singhal, A.B.1
  • 58
    • 0028959228 scopus 로고
    • Cerebroprotective effect of lamotrigine after focal ischemia in rats
    • Smith SE and Meldrum BS. Cerebroprotective effect of lamotrigine after focal ischemia in rats. Stroke 26: 117-122, 1995.
    • (1995) Stroke , vol.26 , pp. 117-122
    • Smith, S.E.1    Meldrum, B.S.2
  • 59
    • 56449100005 scopus 로고    scopus 로고
    • Remote ischemic preconditioning: A novel protective method from ischemia reperfusion injury. A review
    • Tapuria N, Kumar Y, Habib MM, Amara MA, Seifalian AM, and Davidson BR. Remote ischemic preconditioning: A novel protective method from ischemia reperfusion injury. A review. J Surg Res 150: 304-330, 2008.
    • (2008) J Surg Res , vol.150 , pp. 304-330
    • Tapuria, N.1    Kumar, Y.2    Habib, M.M.3    Amara, M.A.4    Seifalian, A.M.5    Davidson, B.R.6
  • 60
    • 0026008909 scopus 로고
    • Oxygen radical mechanisms of brain injury following ischemia and reperfusion
    • Traystman RJ, Kirsch JR, and Koehler RC. Oxygen radical mechanisms of brain injury following ischemia and reperfusion. J Appl Physiol 71: 1185-1195, 1991.
    • (1991) J Appl Physiol , vol.71 , pp. 1185-1195
    • Traystman, R.J.1    Kirsch, J.R.2    Koehler, R.C.3
  • 61
    • 34548126863 scopus 로고    scopus 로고
    • Ethanol preconditioning protects against ischemia/reperfusion-induced brain damage: Role of NADPH oxidase-derived ROS
    • DOI 10.1016/j.freeradbiomed.2007.06.018, PII S0891584907004492
    • Wang Q, Sun AY, Simonyi A, Kalogeris TJ, Miller DK Sun GY, and Korthius RJ. Ethanol preconditioning protects against ischemia=reperfusion-induced brain damage: Role of NADPH oxidase derived ROS. Free Radic Biol Med 43: 1048-1060, 2007. (Pubitemid 47302653)
    • (2007) Free Radical Biology and Medicine , vol.43 , Issue.7 , pp. 1048-1060
    • Wang, Q.1    Sun, A.Y.2    Simonyi, A.3    Kalogeris, T.J.4    Miller, D.K.5    Sun, G.Y.6    Korthuis, R.J.7
  • 62
    • 67649526000 scopus 로고    scopus 로고
    • Poly (ADP-ribose) signals to mitochontrial AIF: A key event in parthanatos
    • Wang Y, Dawson VL, and Dawson TM. Poly (ADP-ribose) signals to mitochontrial AIF: A key event in parthanatos. Exp Neurol 218: 193-202, 2009.
    • (2009) Exp Neurol , vol.218 , pp. 193-202
    • Wang, Y.1    Dawson, V.L.2    Dawson, T.M.3
  • 65
    • 0038587580 scopus 로고    scopus 로고
    • Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity
    • Zhao H, Yenari MA, Cheng D, Sapolsky RM, and Steinberg GK. Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity. J Neurochem 85: 1026-1036, 2003. (Pubitemid 36578634)
    • (2003) Journal of Neurochemistry , vol.85 , Issue.4 , pp. 1026-1036
    • Zhao, H.1    Yenari, M.A.2    Cheng, D.3    Sapolsky, R.M.4    Steinberg, G.K.5
  • 66
    • 77449095409 scopus 로고    scopus 로고
    • Caffeinol at the receptor level. Anti-ischemic effect of N-methyl-D-Aspartate receptor blockade is potentiated by caffeine
    • Zhao X, Strong R, Piriyawa P, Palusinski R, Grotta JC, and Aronowski J. Caffeinol at the receptor level. Anti-ischemic effect of N-methyl-D-Aspartate receptor blockade is potentiated by caffeine. Stroke 41: 363-367, 2010.
    • (2010) Stroke , vol.41 , pp. 363-367
    • Zhao, X.1    Strong, R.2    Piriyawa, P.3    Palusinski, R.4    Grotta, J.C.5    Aronowski, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.