CD8+ T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-α/β signaling

Immunity

Volumn 13, Issue 5, 2000, Pages 643-655

  Hida, Shigeaki ^a   Ogasawara, Kouetsu ^a   Sato, Kojiro ^a   Abe, Masaaki ^b   Takayanagi, Hiroshi ^a   Yokochi, Taeko ^a   Sato, Takeo ^a   Hirose, Sachiko ^b   Shirai, Toshikazu ^b   Taki, Shinsuke ^a   Taniguchi, Tadatsugu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CD8 ANTIGEN; INTERFERON REGULATORY FACTOR 2; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNOSTIMULATION; MOUSE; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKIN DISEASE; T LYMPHOCYTE;

EID: 0033635304     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)00064-9     Document Type: Article

References (65)

1. Synergistic T-T cell interaction present in alloreactivity: Determination of 'MLR helper' T cell subsets
2. Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes
3. The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis
4. The neglected role of type I interferon in the T-cell response: Implications for its clinical use
5. Virus-induced transient bone marrow aplasia: Major role of interferon- α/β during acute infection with the noncytopathic lymphocytic choriomeningitis virus
6. Natural killer cells in antiviral defense: Function and regulation by innate cytokines
7. ISGF3γ p48, a specificity switch for interferon activated transcription factors
8. The physiological interferon response
9. Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus
10. Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis
11. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
12. Side effects of alpha interferon in chronic hepatitis C
13. - T cells to cause immunopathology
14. A new protein containing an SH2 domain that inhibits JAK kinases
15. Mig and IP-10: CXC chemokines that target lymphocytes
16. CD8 is needed for development of cytotoxic T cells but not helper T cells
17. Psoriasis induced by interferon-α
18. Immunologic mechanisms in psoriasis
19. Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis
20. Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice
21. Biologic effects of interferons
22. Functional differences in the promoters of the interferon-inducible (2'-5')A oligoadenylate synthetase and 6-16 genes in interferon-resistant Daudi cells
23. Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes
24. A family of proteins that inhibit signalling through tyrosine kinase receptors
25. Essential and non-redundant roles of p48 (ISGF3γ) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies
26. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
27. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
28. + T cells
29. Inhibitors keep cytokines in check
30. Interleukin-10-deficient mice develop chronic enterocolitis
31. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death
32. Type I cytokines and interferons and their receptors
33. Impairment of T and B cell development by treatment with a type I interferon
34. Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction
35. Biochemical characterization of a gamma interferon-inducible cytokine (IP-10)
36. Interferon regulatory factors: The next generation
37. Type I interferons keep activated T cells alive
38. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development
39. B6.C-H-2bm12. A new H-2 mutation in the I region in the mouse
40. Biology and biochemistry of the chemokines: A family of chemotactic and inflammatory cytokines
41. Structure and function of a new STAT-induced STAT inhibitor
42. Negative regulation of cytokine signaling: STAT-induced STAT inhibitor
43. The growing family of interferon regulatory factors
44. Interferon-independent and -induced regulation of Epstein-Barr virus EBNA-1 gene transcription in Burkitt lymphoma
45. The development of manifest psoriatic lesions is linked with the appearance of ICAM-1 positivity on keratinocytes
46. Psoriasis and alphainterferon
47. + cells but markedly decreased helper cell activity in mice lacking CD4
48. b- restricted antihapten and antiviral cytotoxic T cell populations clonally develop in vitro from murine splenic precursor T cells
49. Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7
50. T cells involved in psoriasis vulgaris belong to the Th1 subset
51. Protective heterologous antiviral immunity and enhanced immunopathogenesis mediated by memory T cell populations
52. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
53. Detection of the interferon-gamma-induced protein 10 in psoriasiform dermatitis of acquired immunodeficiency syndrome
54. A family of cytokine-inducible inhibitors of signalling
55. Psoriasis
56. Induction of type I diabetes by interferon-alpha in transgenic mice
57. Crosstalk between interferon-γ and -α/β signaling components at caveolar membrane domain
58. The transcription factor IRF-1 and its family members in the regulation of host defense
59. Induction of bystander T cell proliferation by viruses and type I interferon in vivo
60. Identification of CRG-2. An interferon-inducible mRNA predicted to encode a murine monokine
61. Interferons
62. A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes
63. The CIS family: Negative regulators of JAKSTAT signaling
64. - T cells in vivo by IL-15