Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 47, 2013, Pages 19036-19041

  Piao, Wenji ^a   Ru, Lisa W ^a   Piepenbrink, Kurt H ^b   Sundberg, Eric J ^a,b,c   Vogel, Stefanie N ^a   Toshchakov, Vladimir Y ^a  

^a Molecular Microbiology and Immunology and Oncology   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c John Hopkins Medical Instituitions   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL ASSAY; CONTROLLED STUDY; HUMAN; IMMUNOPRECIPITATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

DECOY PEPTIDES; SIGNALING COMPLEX ASSEMBLY; TIR DOMAIN RECOGNITION SITE; TLR4 TARGETING;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CIRCULAR DICHROISM; ESCHERICHIA COLI; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INTERFERON-BETA; MICE; MICE, INBRED C57BL; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, INTERLEUKIN; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84888086101     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1313575110     Document Type: Article

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