Negative regulation of Nmi on virus-triggered Type i IFN production by targeting IRF7

Journal of Immunology

Volumn 191, Issue 6, 2013, Pages 3393-3399

  Wang, Jie ^a   Yang, Bo ^b   Hu, Yu ^a   Zheng, Yuhan ^a   Zhou, Haiyan ^a   Wang, Yanming ^b   Ma, Yonglei ^c   Mao, Kairui ^a   Yang, Leilei ^c   Lin, Guomei ^a   Ji, Yongyong ^a   Wu, Xiaodong ^a   Sun, Bing ^a,b,c  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c INSTITUTE PASTEUR OF SHANGHAI   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INTERFERON; INTERFERON REGULATORY FACTOR 7; N MYC AND STATS INTERACTOR; PROTEASOME; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; RNA INTERFERENCE; SENDAI VIRUS; SENDAI VIRUS INFECTION; UBIQUITINATION; UPREGULATION; VESICULAR STOMATITIS VIRUS;

ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INTERFERON REGULATORY FACTOR-7; INTERFERON TYPE I; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; REAL-TIME POLYMERASE CHAIN REACTION; RESPIROVIRUS INFECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENDAI VIRUS; TRANSFECTION;

EID: 84884275991     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300740     Document Type: Article

References (39)

1. Roberts, R. M., L. Liu, Q. Guo, D. Leaman, and J. Bixby. 1998. The evolution of the type I interferons. J. Interferon Cytokine Res. 18: 805-816.
2. Theofilopoulos, A. N., R. Baccala, B. Beutler, and D. H. Kono. 2005. Type I interferons (alpha/beta) in immunity and autoimmunity. Annu. Rev. Immunol. 23: 307-336.
3. Samuel, C. E. 2001. Antiviral actions of interferons. Clin. Microbiol. Rev. 14: 778-809 (table of contents.).
4. Takeda, K., T. Kaisho, and S. Akira. 2003. Toll-like receptors. Annu. Rev. Immunol. 21: 335-376.
5. Takeuchi, O., and S. Akira. 2008. MDA5/RIG-I and virus recognition. Curr. Opin. Immunol. 20: 17-22.
6. Kato, H., O. Takeuchi, S. Sato, M. Yoneyama, M. Yamamoto, K. Matsui, S. Uematsu, A. Jung, T. Kawai, K. J. Ishii, et al. 2006. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441: 101-105.
7. Kawai, T., K. Takahashi, S. Sato, C. Coban, H. Kumar, H. Kato, K. J. Ishii, O. Takeuchi, and S. Akira. 2005. IPS-1, an adaptor triggering RIG-I-and Mda5-mediated type I interferon induction. Nat. Immunol. 6: 981-988.
8. Xu, L. G., Y. Y. Wang, K. J. Han, L. Y. Li, Z. Zhai, and H. B. Shu. 2005. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol. Cell 19: 727-740.
9. Seth, R. B., L. Sun, C. K. Ea, and Z. J. Chen. 2005. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122: 669-682.
10. Meylan, E., J. Curran, K. Hofmann, D. Moradpour, M. Binder, R. Bartenschlager, and J. Tschopp. 2005. Cardif is an adaptor protein in the RIGI antiviral pathway and is targeted by hepatitis C virus. Nature 437: 1167-1172.
11. Saha, S. K., E. M. Pietras, J. Q. He, J. R. Kang, S. Y. Liu, G. Oganesyan, A. Shahangian, B. Zarnegar, T. L. Shiba, Y. Wang, and G. Cheng. 2006. Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif. EMBO J. 25: 3257-3263.
12. Oganesyan, G., S. K. Saha, B. Guo, J. Q. He, A. Shahangian, B. Zarnegar, A. Perry, and G. Cheng. 2006. Critical role of TRAF3 in the Toll-like receptordependent and-independent antiviral response. Nature 439: 208-211.
13. Häcker, H., V. Redecke, B. Blagoev, I. Kratchmarova, L. C. Hsu, G. G. Wang, M. P. Kamps, E. Raz, H. Wagner, G. Häcker, et al. 2006. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 439: 204-207.
14. Sharma, S., B. R. tenOever, N. Grandvaux, G. P. Zhou, R. Lin, and J. Hiscott. 2003. Triggering the interferon antiviral response through an IKK-related pathway. Science 300: 1148-1151.
15. Hiscott, J., P. Pitha, P. Genin, H. Nguyen, C. Heylbroeck, Y. Mamane, M. Algarte, and R. Lin. 1999. Triggering the interferon response: the role of IRF-3 transcription factor. J. Interferon Cytokine Res. 19: 1-13.
16. Lin, R., Y. Mamane, and J. Hiscott. 2000. Multiple regulatory domains control IRF-7 activity in response to virus infection. J. Biol. Chem. 275: 34320-34327.
17. Honda, K., H. Yanai, H. Negishi, M. Asagiri, M. Sato, T. Mizutani, N. Shimada, Y. Ohba, A. Takaoka, N. Yoshida, and T. Taniguchi. 2005. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434: 772-777.
18. Komuro, A., D. Bamming, and C. M. Horvath. 2008. Negative regulation of cytoplasmic RNA-mediated antiviral signaling. Cytokine 43: 350-358.
19. Deng, W., M. Shi, M. Han, J. Zhong, Z. Li, W. Li, Y. Hu, L. Yan, J. Wang, Y. He, et al. 2008. Negative regulation of virus-triggered IFN-beta signaling pathway by alternative splicing of TBK1. J. Biol. Chem. 283: 35590-35597.
20. Hu, Y., J. Wang, B. Yang, N. Zheng, M. Qin, Y. Ji, G. Lin, L. Tian, X. Wu, L.Wu, and B. Sun. 2011. Guanylate binding protein 4 negatively regulates virusinduced type I IFN and antiviral response by targeting IFN regulatory factor 7. J. Immunol. 187: 6456-6462.
21. Liang, Q., H. Deng, X. Li, X. Wu, Q. Tang, T. H. Chang, H. Peng, F. J. Rauscher, III, K. Ozato, and F. Zhu. 2011. Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7. J. Immunol. 187: 4754-4763.
22. Allen, I. C., C. B. Moore, M. Schneider, Y. Lei, B. K. Davis, M. A. Scull, D. Gris, K. E. Roney, A. G. Zimmermann, J. B. Bowzard, et al. 2011. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-kB signaling pathways. Immunity 34: 854-865.
23. Gao, L., H. Coope, S. Grant, A. Ma, S. C. Ley, and E. W. Harhaj. 2011. ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling. J. Biol. Chem. 286: 36592-36602.
24. Yang, Y. K., H. Qu, D. Gao, W. Di, H. W. Chen, X. Guo, Z. H. Zhai, and D. Y. Chen. 2011. ARF-like protein 16 (ARL16) inhibits RIG-I by binding with its C-terminal domain in a GTP-dependent manner. J. Biol. Chem. 286: 10568-10580.
25. Kubota, T., M. Matsuoka, S. Xu, N. Otsuki, M. Takeda, A. Kato, and K. Ozato. 2011. PIASy inhibits virus-induced and interferon-stimulated transcription through distinct mechanisms. J. Biol. Chem. 286: 8165-8175.
26. Lebrun, S. J., R. L. Shpall, and L. Naumovski. 1998. Interferon-induced upregulation and cytoplasmic localization of Myc-interacting protein Nmi. J. Interferon Cytokine Res. 18: 767-771.
27. Bannasch, D., I. Weis, and M. Schwab. 1999. Nmi protein interacts with regions that differ between MycN and Myc and is localized in the cytoplasm of neuroblastoma cells in contrast to nuclear MycN. Oncogene 18: 6810-6817.
28. Sakamuro, D., and G. C. Prendergast. 1999. New Myc-interacting proteins: a second Myc network emerges. Oncogene 18: 2942-2954.
29. Schlierf, B., S. Lang, T. Kosian, T. Werner, and M. Wegner. 2005. The highmobility group transcription factor Sox10 interacts with the N-myc-interacting protein Nmi. J. Mol. Biol. 353: 1033-1042.
30. Zhou, X., J. Liao, A. Meyerdierks, L. Feng, L. Naumovski, E. C. Bottger, and M. B. Omary. 2000. Interferon-alpha induces nmi-IFP35 heterodimeric complex formation that is affected by the phosphorylation of IFP35. J. Biol. Chem. 275: 21364-21371.
31. Lee, N. D., J. Chen, R. L. Shpall, and L. Naumovski. 1999. Subcellular localization of interferon-inducible Myc/stat-interacting protein Nmi is regulated by a novel IFP 35 homologous domain. J. Interferon Cytokine Res. 19: 1245-1252.
32. Chen, J., R. L. Shpall, A. Meyerdierks, M. Hagemeier, E. C. Böttger, and L. Naumovski. 2000. Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35. J. Biol. Chem. 275: 36278-36284.
33. Zhang, K., G. Zheng, and Y. C. Yang. 2007. Stability of Nmi protein is controlled by its association with Tip60. Mol. Cell. Biochem. 303: 1-8.
34. Zhang, L., Y. Tang, Y. Tie, C. Tian, J. Wang, Y. Dong, Z. Sun, and F. He. 2007. The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling. Cell. Signal. 19: 932-944.
35. Zhu, M., S. John, M. Berg, and W. J. Leonard. 1999. Functional association of Nmi with Stat5 and Stat1 in IL-2-and IFNgamma-mediated signaling. Cell 96: 121-130.
36. Tan, J., W. Qiao, J. Wang, F. Xu, Y. Li, J. Zhou, Q. Chen, and Y. Geng. 2008. IFP35 is involved in the antiviral function of interferon by association with the viral tas transactivator of bovine foamy virus. J. Virol. 82: 4275-4283.
37. Fillmore, R. A., A. Mitra, Y. Xi, J. Ju, J. Scammell, L. A. Shevde, and R. S. Samant. 2009. Nmi (N-Myc interactor) inhibits Wnt/beta-catenin signaling and retards tumor growth. Int. J. Cancer 125: 556-564.
38. Hou, W., Y. Wu, S. Sun, M. Shi, Y. Sun, C. Yang, G. Pei, Y. Gu, C. Zhong, and B. Sun. 2003. Pertussis toxin enhances Th1 responses by stimulation of dendritic cells. J. Immunol. 170: 1728-1736.
39. Huang, C., E. Bi, Y. Hu, W. Deng, Z. Tian, C. Dong, Y. Hu, and B. Sun. 2006. A novel NF-kappaB binding site controls human granzyme B gene transcription. J. Immunol. 176: 4173-4181.