메뉴 건너뛰기




Volumn 1852, Issue 2, 2015, Pages 365-378

Interferon regulatory factors: At the crossroads of immunity, metabolism, and disease

Author keywords

Disease; Immunity; IRFs; Metabolism; Stress sensor

Indexed keywords

DNA; INTERFERON REGULATORY FACTOR; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1;

EID: 84919795881     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.04.030     Document Type: Article
Times cited : (165)

References (138)
  • 1
    • 42649114059 scopus 로고    scopus 로고
    • The IRF family transcription factors in immunity and oncogenesis
    • Tamura T., Yanai H., Savitsky D., Taniguchi T. The IRF family transcription factors in immunity and oncogenesis. Annu. Rev. Immunol. 2008, 26:535-584.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 535-584
    • Tamura, T.1    Yanai, H.2    Savitsky, D.3    Taniguchi, T.4
  • 2
    • 33748051738 scopus 로고    scopus 로고
    • IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
    • Honda K., Taniguchi T. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat. Rev. Immunol. 2006, 6:644-658.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 644-658
    • Honda, K.1    Taniguchi, T.2
  • 3
    • 34250017968 scopus 로고    scopus 로고
    • An atomic model of the interferon-beta enhanceosome
    • Panne D., Maniatis T., Harrison S.C. An atomic model of the interferon-beta enhanceosome. Cell 2007, 129:1111-1123.
    • (2007) Cell , vol.129 , pp. 1111-1123
    • Panne, D.1    Maniatis, T.2    Harrison, S.C.3
  • 4
    • 77949913872 scopus 로고    scopus 로고
    • Structural insights into interferon regulatory factor activation
    • Chen W., Royer W.E. Structural insights into interferon regulatory factor activation. Cell. Signal. 2010, 22:883-887.
    • (2010) Cell. Signal. , vol.22 , pp. 883-887
    • Chen, W.1    Royer, W.E.2
  • 5
    • 77449101221 scopus 로고    scopus 로고
    • Regulation of immunity and oncogenesis by the IRF transcription factor family
    • Savitsky D., Tamura T., Yanai H., Taniguchi T. Regulation of immunity and oncogenesis by the IRF transcription factor family. Cancer Immunol. Immunother. 2010, 59:489-510.
    • (2010) Cancer Immunol. Immunother. , vol.59 , pp. 489-510
    • Savitsky, D.1    Tamura, T.2    Yanai, H.3    Taniguchi, T.4
  • 6
    • 84877656613 scopus 로고    scopus 로고
    • The IRF family of transcription factors: Inception, impact and implications in oncogenesis
    • Yanai H., Negishi H., Taniguchi T. The IRF family of transcription factors: Inception, impact and implications in oncogenesis. Oncoimmunology 2012, 1:1376-1386.
    • (2012) Oncoimmunology , vol.1 , pp. 1376-1386
    • Yanai, H.1    Negishi, H.2    Taniguchi, T.3
  • 25
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi O., Akira S. Pattern recognition receptors and inflammation. Cell 2010, 140:805-820.
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 26
    • 84904915021 scopus 로고    scopus 로고
    • The IRF Family Transcription Factors at the Interface of Innate and Adaptive Immune Responses
    • Ikushima H., Negishi H., Taniguchi T. The IRF Family Transcription Factors at the Interface of Innate and Adaptive Immune Responses. Cold Spring Harb. Symp. Quant. Biol. 2013, 10.1101/sqb.2013.78.020321.
    • (2013) Cold Spring Harb. Symp. Quant. Biol.
    • Ikushima, H.1    Negishi, H.2    Taniguchi, T.3
  • 27
    • 34548656855 scopus 로고    scopus 로고
    • Signaling pathways downstream of pattern-recognition receptors and their cross talk
    • Lee M.S., Kim Y.J. Signaling pathways downstream of pattern-recognition receptors and their cross talk. Annu. Rev. Biochem. 2007, 76:447-480.
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 447-480
    • Lee, M.S.1    Kim, Y.J.2
  • 28
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai T., Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011, 34:637-650.
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 29
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
    • Kawai T., Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 2010, 11:373-384.
    • (2010) Nat. Immunol. , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 31
    • 57349121051 scopus 로고    scopus 로고
    • Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination
    • Balkhi M.Y., Fitzgerald K.A., Pitha P.M. Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination. Mol. Cell. Biol. 2008, 28:7296-7308.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 7296-7308
    • Balkhi, M.Y.1    Fitzgerald, K.A.2    Pitha, P.M.3
  • 35
    • 67649840704 scopus 로고    scopus 로고
    • Signalling through C-type lectin receptors: shaping immune responses
    • Geijtenbeek T.B., Gringhuis S.I. Signalling through C-type lectin receptors: shaping immune responses. Nat. Rev. Immunol. 2009, 9:465-479.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 465-479
    • Geijtenbeek, T.B.1    Gringhuis, S.I.2
  • 36
    • 84859405717 scopus 로고    scopus 로고
    • Signaling by myeloid C-type lectin receptors in immunity and homeostasis
    • Sancho D., Reis e Sousa C. Signaling by myeloid C-type lectin receptors in immunity and homeostasis. Annu. Rev. Immunol. 2012, 30:491-529.
    • (2012) Annu. Rev. Immunol. , vol.30 , pp. 491-529
    • Sancho, D.1    Reis e Sousa, C.2
  • 37
    • 84879602096 scopus 로고    scopus 로고
    • Interferon-beta production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans
    • del Fresno C., Soulat D., Roth S., Blazek K., Udalova I., Sancho D., Ruland J., Ardavin C. Interferon-beta production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans. Immunity 2013, 38:1176-1186.
    • (2013) Immunity , vol.38 , pp. 1176-1186
    • del Fresno, C.1    Soulat, D.2    Roth, S.3    Blazek, K.4    Udalova, I.5    Sancho, D.6    Ruland, J.7    Ardavin, C.8
  • 41
    • 84878190840 scopus 로고    scopus 로고
    • Immune sensing of DNA
    • Paludan S.R., Bowie A.G. Immune sensing of DNA. Immunity 2013, 38:870-880.
    • (2013) Immunity , vol.38 , pp. 870-880
    • Paludan, S.R.1    Bowie, A.G.2
  • 42
    • 53349178089 scopus 로고    scopus 로고
    • STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
    • Ishikawa H., Barber G.N. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 2008, 455:674-678.
    • (2008) Nature , vol.455 , pp. 674-678
    • Ishikawa, H.1    Barber, G.N.2
  • 43
    • 84857937262 scopus 로고    scopus 로고
    • STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway
    • Tanaka Y., Chen Z.J. STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway. Sci. Signal. 2012, 5:ra20.
    • (2012) Sci. Signal. , vol.5 , pp. ra20
    • Tanaka, Y.1    Chen, Z.J.2
  • 45
    • 84882896267 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses
    • Gao D., Wu J., Wu Y.T., Du F., Aroh C., Yan N., Sun L., Chen Z.J. Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses. Science 2013, 341:903-906.
    • (2013) Science , vol.341 , pp. 903-906
    • Gao, D.1    Wu, J.2    Wu, Y.T.3    Du, F.4    Aroh, C.5    Yan, N.6    Sun, L.7    Chen, Z.J.8
  • 46
    • 84873711885 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
    • Sun L., Wu J., Du F., Chen X., Chen Z.J. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 2013, 339:786-791.
    • (2013) Science , vol.339 , pp. 786-791
    • Sun, L.1    Wu, J.2    Du, F.3    Chen, X.4    Chen, Z.J.5
  • 47
    • 84873724533 scopus 로고    scopus 로고
    • Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
    • Wu J., Sun L., Chen X., Du F., Shi H., Chen C., Chen Z.J. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 2013, 339:826-830.
    • (2013) Science , vol.339 , pp. 826-830
    • Wu, J.1    Sun, L.2    Chen, X.3    Du, F.4    Shi, H.5    Chen, C.6    Chen, Z.J.7
  • 50
    • 84868095535 scopus 로고    scopus 로고
    • Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein
    • Orzalli M.H., DeLuca N.A., Knipe D.M. Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:E3008-E3017.
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. E3008-E3017
    • Orzalli, M.H.1    DeLuca, N.A.2    Knipe, D.M.3
  • 52
    • 80052969639 scopus 로고    scopus 로고
    • The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
    • Zhang Z., Yuan B., Bao M., Lu N., Kim T., Liu Y.J. The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells. Nat. Immunol. 2011, 12:959-965.
    • (2011) Nat. Immunol. , vol.12 , pp. 959-965
    • Zhang, Z.1    Yuan, B.2    Bao, M.3    Lu, N.4    Kim, T.5    Liu, Y.J.6
  • 53
    • 77952566304 scopus 로고    scopus 로고
    • The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway
    • Yang P., An H., Liu X., Wen M., Zheng Y., Rui Y., Cao X. The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway. Nat. Immunol. 2010, 11:487-494.
    • (2010) Nat. Immunol. , vol.11 , pp. 487-494
    • Yang, P.1    An, H.2    Liu, X.3    Wen, M.4    Zheng, Y.5    Rui, Y.6    Cao, X.7
  • 55
    • 84884332722 scopus 로고    scopus 로고
    • Mechanisms of NOD-like receptor-associated inflammasome activation
    • Wen H., Miao E.A., Ting J.P. Mechanisms of NOD-like receptor-associated inflammasome activation. Immunity 2013, 39:432-441.
    • (2013) Immunity , vol.39 , pp. 432-441
    • Wen, H.1    Miao, E.A.2    Ting, J.P.3
  • 57
    • 84857846174 scopus 로고    scopus 로고
    • Activation of interferon regulatory factor 5 by site specific phosphorylation
    • Chang Foreman H.C., Van Scoy S., Cheng T.F., Reich N.C. Activation of interferon regulatory factor 5 by site specific phosphorylation. PLoS ONE 2012, 7:e33098.
    • (2012) PLoS ONE , vol.7 , pp. e33098
    • Chang Foreman, H.C.1    Van Scoy, S.2    Cheng, T.F.3    Reich, N.C.4
  • 59
    • 84856159067 scopus 로고    scopus 로고
    • Transcriptional programming of the dendritic cell network
    • Belz G.T., Nutt S.L. Transcriptional programming of the dendritic cell network. Nat. Rev. Immunol. 2012, 12:101-113.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 101-113
    • Belz, G.T.1    Nutt, S.L.2
  • 60
    • 84866527686 scopus 로고    scopus 로고
    • IRF4 promotes cutaneous dendritic cell migration to lymph nodes during homeostasis and inflammation
    • Bajana S., Roach K., Turner S., Paul J., Kovats S. IRF4 promotes cutaneous dendritic cell migration to lymph nodes during homeostasis and inflammation. J. Immunol. 2012, 189:3368-3377.
    • (2012) J. Immunol. , vol.189 , pp. 3368-3377
    • Bajana, S.1    Roach, K.2    Turner, S.3    Paul, J.4    Kovats, S.5
  • 65
    • 41549151507 scopus 로고    scopus 로고
    • The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8
    • Esashi E., Wang Y.H., Perng O., Qin X.F., Liu Y.J., Watowich S.S. The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8. Immunity 2008, 28:509-520.
    • (2008) Immunity , vol.28 , pp. 509-520
    • Esashi, E.1    Wang, Y.H.2    Perng, O.3    Qin, X.F.4    Liu, Y.J.5    Watowich, S.S.6
  • 66
    • 41349119601 scopus 로고    scopus 로고
    • The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse
    • Tailor P., Tamura T., Morse H.C., Ozato K. The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse. Blood 2008, 111:1942-1945.
    • (2008) Blood , vol.111 , pp. 1942-1945
    • Tailor, P.1    Tamura, T.2    Morse, H.C.3    Ozato, K.4
  • 67
    • 84857724877 scopus 로고    scopus 로고
    • IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors
    • Becker A.M., Michael D.G., Satpathy A.T., Sciammas R., Singh H., Bhattacharya D. IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors. Blood 2012, 119:2003-2012.
    • (2012) Blood , vol.119 , pp. 2003-2012
    • Becker, A.M.1    Michael, D.G.2    Satpathy, A.T.3    Sciammas, R.4    Singh, H.5    Bhattacharya, D.6
  • 71
    • 84879689439 scopus 로고    scopus 로고
    • Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks
    • Murphy T.L., Tussiwand R., Murphy K.M. Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks. Nat. Rev. Immunol. 2013, 13:499-509.
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 499-509
    • Murphy, T.L.1    Tussiwand, R.2    Murphy, K.M.3
  • 73
    • 1442330451 scopus 로고    scopus 로고
    • Negative regulation of IFN-alpha/beta signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells
    • Honda K., Mizutani T., Taniguchi T. Negative regulation of IFN-alpha/beta signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:2416-2421.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 2416-2421
    • Honda, K.1    Mizutani, T.2    Taniguchi, T.3
  • 76
    • 84884371024 scopus 로고    scopus 로고
    • Transcriptional control of macrophage identity, self-renewal, and function
    • Molawi K., Sieweke M.H. Transcriptional control of macrophage identity, self-renewal, and function. Adv. Immunol. 2013, 120:269-300.
    • (2013) Adv. Immunol. , vol.120 , pp. 269-300
    • Molawi, K.1    Sieweke, M.H.2
  • 77
    • 24744458604 scopus 로고    scopus 로고
    • Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages
    • Tamura T., Thotakura P., Tanaka T.S., Ko M.S., Ozato K. Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages. Blood 2005, 106:1938-1947.
    • (2005) Blood , vol.106 , pp. 1938-1947
    • Tamura, T.1    Thotakura, P.2    Tanaka, T.S.3    Ko, M.S.4    Ozato, K.5
  • 78
    • 84866565809 scopus 로고    scopus 로고
    • The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation
    • Chang T.H., Xu S., Tailor P., Kanno T., Ozato K. The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation. J. Immunol. 2012, 189:3548-3556.
    • (2012) J. Immunol. , vol.189 , pp. 3548-3556
    • Chang, T.H.1    Xu, S.2    Tailor, P.3    Kanno, T.4    Ozato, K.5
  • 83
    • 58149311492 scopus 로고    scopus 로고
    • IFN consensus sequence binding protein (Icsbp) is critical for eosinophil development
    • Milanovic M., Terszowski G., Struck D., Liesenfeld O., Carstanjen D. IFN consensus sequence binding protein (Icsbp) is critical for eosinophil development. J. Immunol. 2008, 181:5045-5053.
    • (2008) J. Immunol. , vol.181 , pp. 5045-5053
    • Milanovic, M.1    Terszowski, G.2    Struck, D.3    Liesenfeld, O.4    Carstanjen, D.5
  • 84
    • 24744453077 scopus 로고    scopus 로고
    • Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance
    • Hida S., Tadachi M., Saito T., Taki S. Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance. Blood 2005, 106:2011-2017.
    • (2005) Blood , vol.106 , pp. 2011-2017
    • Hida, S.1    Tadachi, M.2    Saito, T.3    Taki, S.4
  • 86
    • 0029805028 scopus 로고    scopus 로고
    • The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo
    • Duncan G.S., Mittrucker H.W., Kagi D., Matsuyama T., Mak T.W. The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo. J. Exp. Med. 1996, 184:2043-2048.
    • (1996) J. Exp. Med. , vol.184 , pp. 2043-2048
    • Duncan, G.S.1    Mittrucker, H.W.2    Kagi, D.3    Matsuyama, T.4    Mak, T.W.5
  • 87
    • 0034617994 scopus 로고    scopus 로고
    • Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells
    • Lohoff M., Duncan G.S., Ferrick D., Mittrucker H.W., Bischof S., Prechtl S., Rollinghoff M., Schmitt E., Pahl A., Mak T.W. Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells. J. Exp. Med. 2000, 192:325-336.
    • (2000) J. Exp. Med. , vol.192 , pp. 325-336
    • Lohoff, M.1    Duncan, G.S.2    Ferrick, D.3    Mittrucker, H.W.4    Bischof, S.5    Prechtl, S.6    Rollinghoff, M.7    Schmitt, E.8    Pahl, A.9    Mak, T.W.10
  • 88
    • 0032536787 scopus 로고    scopus 로고
    • The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells
    • Ohteki T., Yoshida H., Matsuyama T., Duncan G.S., Mak T.W., Ohashi P.S. The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells. J. Exp. Med. 1998, 187:967-972.
    • (1998) J. Exp. Med. , vol.187 , pp. 967-972
    • Ohteki, T.1    Yoshida, H.2    Matsuyama, T.3    Duncan, G.S.4    Mak, T.W.5    Ohashi, P.S.6
  • 90
    • 18644382503 scopus 로고    scopus 로고
    • IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells
    • Taki S., Nakajima S., Ichikawa E., Saito T., Hida S. IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells. J. Immunol. 2005, 174:6005-6012.
    • (2005) J. Immunol. , vol.174 , pp. 6005-6012
    • Taki, S.1    Nakajima, S.2    Ichikawa, E.3    Saito, T.4    Hida, S.5
  • 91
    • 58149148414 scopus 로고    scopus 로고
    • IRF8 regulates B-cell lineage specification, commitment, and differentiation
    • Wang H., Lee C.H., Qi C., Tailor P., Feng J., Abbasi S., Atsumi T., Morse H.C. IRF8 regulates B-cell lineage specification, commitment, and differentiation. Blood 2008, 112:4028-4038.
    • (2008) Blood , vol.112 , pp. 4028-4038
    • Wang, H.1    Lee, C.H.2    Qi, C.3    Tailor, P.4    Feng, J.5    Abbasi, S.6    Atsumi, T.7    Morse, H.C.8
  • 92
    • 0038506030 scopus 로고    scopus 로고
    • IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development
    • Lu R., Medina K.L., Lancki D.W., Singh H. IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev. 2003, 17:1703-1708.
    • (2003) Genes Dev. , vol.17 , pp. 1703-1708
    • Lu, R.1    Medina, K.L.2    Lancki, D.W.3    Singh, H.4
  • 93
    • 33751567260 scopus 로고    scopus 로고
    • IFN regulatory factor 4 and 8 promote Ig light chain kappa locus activation in pre-B cell development
    • Ma S., Turetsky A., Trinh L., Lu R. IFN regulatory factor 4 and 8 promote Ig light chain kappa locus activation in pre-B cell development. J. Immunol. 2006, 177:7898-7904.
    • (2006) J. Immunol. , vol.177 , pp. 7898-7904
    • Ma, S.1    Turetsky, A.2    Trinh, L.3    Lu, R.4
  • 94
    • 40249112989 scopus 로고    scopus 로고
    • Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling
    • Johnson K., Hashimshony T., Sawai C.M., Pongubala J.M., Skok J.A., Aifantis I., Singh H. Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling. Immunity 2008, 28:335-345.
    • (2008) Immunity , vol.28 , pp. 335-345
    • Johnson, K.1    Hashimshony, T.2    Sawai, C.M.3    Pongubala, J.M.4    Skok, J.A.5    Aifantis, I.6    Singh, H.7
  • 95
    • 33750839981 scopus 로고    scopus 로고
    • Stages of germinal center transit are defined by B cell transcription factor coexpression and relative abundance
    • Cattoretti G., Shaknovich R., Smith P.M., Jack H.M., Murty V.V., Alobeid B. Stages of germinal center transit are defined by B cell transcription factor coexpression and relative abundance. J. Immunol. 2006, 177:6930-6939.
    • (2006) J. Immunol. , vol.177 , pp. 6930-6939
    • Cattoretti, G.1    Shaknovich, R.2    Smith, P.M.3    Jack, H.M.4    Murty, V.V.5    Alobeid, B.6
  • 96
    • 33747133955 scopus 로고    scopus 로고
    • Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation
    • Sciammas R., Shaffer A.L., Schatz J.H., Zhao H., Staudt L.M., Singh H. Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity 2006, 25:225-236.
    • (2006) Immunity , vol.25 , pp. 225-236
    • Sciammas, R.1    Shaffer, A.L.2    Schatz, J.H.3    Zhao, H.4    Staudt, L.M.5    Singh, H.6
  • 99
    • 79251561555 scopus 로고    scopus 로고
    • IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools
    • Feng J., Wang H., Shin D.M., Masiuk M., Qi C.F., Morse H.C. IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools. J. Immunol. 2011, 186:1458-1466.
    • (2011) J. Immunol. , vol.186 , pp. 1458-1466
    • Feng, J.1    Wang, H.2    Shin, D.M.3    Masiuk, M.4    Qi, C.F.5    Morse, H.C.6
  • 101
    • 34548237299 scopus 로고    scopus 로고
    • A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma
    • Saito M., Gao J., Basso K., Kitagawa Y., Smith P.M., Bhagat G., Pernis A., Pasqualucci L., Dalla-Favera R. A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma. Cancer Cell 2007, 12:280-292.
    • (2007) Cancer Cell , vol.12 , pp. 280-292
    • Saito, M.1    Gao, J.2    Basso, K.3    Kitagawa, Y.4    Smith, P.M.5    Bhagat, G.6    Pernis, A.7    Pasqualucci, L.8    Dalla-Favera, R.9
  • 102
    • 79957566441 scopus 로고    scopus 로고
    • An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling
    • Sciammas R., Li Y., Warmflash A., Song Y., Dinner A.R., Singh H. An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling. Mol. Syst. Biol. 2011, 7:495.
    • (2011) Mol. Syst. Biol. , vol.7 , pp. 495
    • Sciammas, R.1    Li, Y.2    Warmflash, A.3    Song, Y.4    Dinner, A.R.5    Singh, H.6
  • 103
    • 84890808213 scopus 로고    scopus 로고
    • IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity
    • Simonetti G., Carette A., Silva K., Wang H., De Silva N.S., Heise N., Siebel C.W., Shlomchik M.J., Klein U. IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity. J. Exp. Med. 2013, 210:2887-2902.
    • (2013) J. Exp. Med. , vol.210 , pp. 2887-2902
    • Simonetti, G.1    Carette, A.2    Silva, K.3    Wang, H.4    De Silva, N.S.5    Heise, N.6    Siebel, C.W.7    Shlomchik, M.J.8    Klein, U.9
  • 104
    • 84887507709 scopus 로고    scopus 로고
    • Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation
    • Yao S., Buzo B.F., Pham D., Jiang L., Taparowsky E.J., Kaplan M.H., Sun J. Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation. Immunity 2013, 39:833-845.
    • (2013) Immunity , vol.39 , pp. 833-845
    • Yao, S.1    Buzo, B.F.2    Pham, D.3    Jiang, L.4    Taparowsky, E.J.5    Kaplan, M.H.6    Sun, J.7
  • 108
    • 37349040852 scopus 로고    scopus 로고
    • The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells
    • Kano S., Sato K., Morishita Y., Vollstedt S., Kim S., Bishop K., Honda K., Kubo M., Taniguchi T. The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells. Nat. Immunol. 2008, 9:34-41.
    • (2008) Nat. Immunol. , vol.9 , pp. 34-41
    • Kano, S.1    Sato, K.2    Morishita, Y.3    Vollstedt, S.4    Kim, S.5    Bishop, K.6    Honda, K.7    Kubo, M.8    Taniguchi, T.9
  • 109
    • 57349118423 scopus 로고    scopus 로고
    • Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naive vs. effector/memory CD4+ T cells
    • Honma K., Kimura D., Tominaga N., Miyakoda M., Matsuyama T., Yui K. Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naive vs. effector/memory CD4+ T cells. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:15890-15895.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 15890-15895
    • Honma, K.1    Kimura, D.2    Tominaga, N.3    Miyakoda, M.4    Matsuyama, T.5    Yui, K.6
  • 111
    • 77956361520 scopus 로고    scopus 로고
    • Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice
    • Biswas P.S., Gupta S., Chang E., Song L., Stirzaker R.A., Liao J.K., Bhagat G., Pernis A.B. Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice. J. Clin. Invest. 2010, 120:3280-3295.
    • (2010) J. Clin. Invest. , vol.120 , pp. 3280-3295
    • Biswas, P.S.1    Gupta, S.2    Chang, E.3    Song, L.4    Stirzaker, R.A.5    Liao, J.K.6    Bhagat, G.7    Pernis, A.B.8
  • 112
    • 84859979283 scopus 로고    scopus 로고
    • Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells
    • Valdez P.A., Vithayathil P.J., Janelsins B.M., Shaffer A.L., Williamson P.R., Datta S.K. Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells. Immunity 2012, 36:668-679.
    • (2012) Immunity , vol.36 , pp. 668-679
    • Valdez, P.A.1    Vithayathil, P.J.2    Janelsins, B.M.3    Shaffer, A.L.4    Williamson, P.R.5    Datta, S.K.6
  • 120
    • 56749164791 scopus 로고    scopus 로고
    • Nutrient sensing and inflammation in metabolic diseases
    • Hotamisligil G.S., Erbay E. Nutrient sensing and inflammation in metabolic diseases. Nat. Rev. Immunol. 2008, 8:923-934.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 923-934
    • Hotamisligil, G.S.1    Erbay, E.2
  • 121
    • 19044393872 scopus 로고    scopus 로고
    • Adipose tissue, inflammation, and cardiovascular disease
    • Berg A.H., Scherer P.E. Adipose tissue, inflammation, and cardiovascular disease. Circ. Res. 2005, 96:939-949.
    • (2005) Circ. Res. , vol.96 , pp. 939-949
    • Berg, A.H.1    Scherer, P.E.2
  • 122
    • 84881255428 scopus 로고    scopus 로고
    • Type I interferon in neurological disease-the devil from within
    • Hofer M.J., Campbell I.L. Type I interferon in neurological disease-the devil from within. Cytokine Growth Factor Rev. 2013, 24:257-267.
    • (2013) Cytokine Growth Factor Rev. , vol.24 , pp. 257-267
    • Hofer, M.J.1    Campbell, I.L.2
  • 123
    • 84866563644 scopus 로고    scopus 로고
    • Targeting IRF4 in autoimmune diseases
    • Xu W.D., Pan H.F., Ye D.Q., Xu Y. Targeting IRF4 in autoimmune diseases. Autoimmun. Rev. 2012, 11:918-924.
    • (2012) Autoimmun. Rev. , vol.11 , pp. 918-924
    • Xu, W.D.1    Pan, H.F.2    Ye, D.Q.3    Xu, Y.4
  • 124
    • 84901066297 scopus 로고    scopus 로고
    • Epigenetics and the IRFs: A complex interplay in the control of immunity and autoimmunity
    • Rogatsky I., Chandrasekaran U., Manni M., Yi W., Pernis A.B. Epigenetics and the IRFs: A complex interplay in the control of immunity and autoimmunity. Autoimmunity 2013, 10.3109/08916934.2013.853050.
    • (2013) Autoimmunity
    • Rogatsky, I.1    Chandrasekaran, U.2    Manni, M.3    Yi, W.4    Pernis, A.B.5
  • 125
    • 84888131271 scopus 로고    scopus 로고
    • Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization
    • Eguchi J., Kong X., Tenta M., Wang X., Kang S., Rosen E.D. Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization. Diabetes 2013, 62:3394-3403.
    • (2013) Diabetes , vol.62 , pp. 3394-3403
    • Eguchi, J.1    Kong, X.2    Tenta, M.3    Wang, X.4    Kang, S.5    Rosen, E.D.6
  • 128
    • 84897085593 scopus 로고    scopus 로고
    • Interferon Regulatory Factors in Heart: Stress Response Beyond Inflammation
    • Sun H., Wang Y. Interferon Regulatory Factors in Heart: Stress Response Beyond Inflammation. Hypertension 2014, 63:663-664.
    • (2014) Hypertension , vol.63 , pp. 663-664
    • Sun, H.1    Wang, Y.2
  • 129
    • 33749059726 scopus 로고    scopus 로고
    • The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration
    • Hauser S.L., Oksenberg J.R. The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration. Neuron 2006, 52:61-76.
    • (2006) Neuron , vol.52 , pp. 61-76
    • Hauser, S.L.1    Oksenberg, J.R.2
  • 130
    • 84866673725 scopus 로고    scopus 로고
    • Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia
    • Horiuchi M., Wakayama K., Itoh A., Kawai K., Pleasure D., Ozato K., Itoh T. Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia. J. Neuroinflammation 2012, 9:227.
    • (2012) J. Neuroinflammation , vol.9 , pp. 227
    • Horiuchi, M.1    Wakayama, K.2    Itoh, A.3    Kawai, K.4    Pleasure, D.5    Ozato, K.6    Itoh, T.7
  • 131
    • 84875950146 scopus 로고    scopus 로고
    • IFN regulatory factor 8 is a key constitutive determinant of the morphological and molecular properties of microglia in the CNS
    • Minten C., Terry R., Deffrasnes C., King N.J., Campbell I.L. IFN regulatory factor 8 is a key constitutive determinant of the morphological and molecular properties of microglia in the CNS. PLoS ONE 2012, 7:e49851.
    • (2012) PLoS ONE , vol.7 , pp. e49851
    • Minten, C.1    Terry, R.2    Deffrasnes, C.3    King, N.J.4    Campbell, I.L.5
  • 132
    • 84861123981 scopus 로고    scopus 로고
    • IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype
    • Masuda T., Tsuda M., Yoshinaga R., Tozaki-Saitoh H., Ozato K., Tamura T., Inoue K. IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype. Cell Rep. 2012, 1:334-340.
    • (2012) Cell Rep. , vol.1 , pp. 334-340
    • Masuda, T.1    Tsuda, M.2    Yoshinaga, R.3    Tozaki-Saitoh, H.4    Ozato, K.5    Tamura, T.6    Inoue, K.7
  • 133
    • 0032481352 scopus 로고    scopus 로고
    • Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300
    • Yoneyama M., Suhara W., Fukuhara Y., Fukuda M., Nishida E., Fujita T. Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300. EMBO J. 1998, 17:1087-1095.
    • (1998) EMBO J. , vol.17 , pp. 1087-1095
    • Yoneyama, M.1    Suhara, W.2    Fukuhara, Y.3    Fukuda, M.4    Nishida, E.5    Fujita, T.6
  • 134
    • 34249281690 scopus 로고    scopus 로고
    • Stressing the role of FoxO proteins in lifespan and disease
    • van der Horst A., Burgering B.M. Stressing the role of FoxO proteins in lifespan and disease. Nat. Rev. Mol. Cell Biol. 2007, 8:440-450.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 440-450
    • van der Horst, A.1    Burgering, B.M.2
  • 136
  • 137
    • 84891450164 scopus 로고    scopus 로고
    • Histone deacetylase sirtuin 1 deacetylates IRF1 protein and programs dendritic cells to control Th17 protein differentiation during autoimmune inflammation
    • Yang H., Lee S.M., Gao B., Zhang J., Fang D. Histone deacetylase sirtuin 1 deacetylates IRF1 protein and programs dendritic cells to control Th17 protein differentiation during autoimmune inflammation. J. Biol. Chem. 2013, 288:37256-37266.
    • (2013) J. Biol. Chem. , vol.288 , pp. 37256-37266
    • Yang, H.1    Lee, S.M.2    Gao, B.3    Zhang, J.4    Fang, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.