IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells

Journal of Immunology

Volumn 174, Issue 10, 2005, Pages 6005-6012

  Taki, Shinsuke ^a   Nakajima, Shinsuke ^a   Ichikawa, Eri ^a   Saito, Takashi ^b   Hida, Shigeaki ^a  

^a SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; INTERFERON REGULATORY FACTOR 2; TRANSCRIPTION FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE ACTIVATION; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL DEATH; CELL MATURATION; CELLULAR IMMUNITY; COMPLEMENT DEFICIENCY; GENE EXPRESSION REGULATION; IMMUNE RESPONSE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 18644382503     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.10.6005     Document Type: Article

References (39)

1. Raulet, D. H. 2003. Natural killer cells. In Fundamental Immunology. W. E. Paul, ed. Lipincott Williams-Wilkins New York. p. 365-391.
2. Yokoyama, W. M., S. Kim, and A. R. French. 2004. The dynamic life of natural killer cells. Annu. Rev. Immunol. 22: 405-429.
3. Colucci, F., M. A. Caligiuri, and J. P. Di Santo. 2003. What does it take to make a natural killer? Nat. Rev. Immunol. 3: 413-425.
4. Dorfman, J. R., and D. H. Raulet. 1998. Acquisition of Ly49 receptor expression by developing natural killer cells. J. Exp. Med. 187: 609-618.
5. Williams, N. S., A. Kubota, M. Bennett, V. Kumar, and F. Takei. 2000. Clonal analysis of NK cell development from bone marrow progenitors in vitro: orderly acquisition of receptor gene expression. Eur. J. Immunol. 30: 2074-2082.
6. Kim, S., K. Iizuka, H. S. Kang, A. Dokun, A. R. French, S. Greco, and W. M. Yokoyama. 2002. In vivo developmental stages in murine natural killer cell maturation. Nat. Immunol. 3: 523-528.
7. Raulet, D. H., R. E. Vance, and C. W. McMahon. 2001. Regulation of the natural killer cell receptor repertoire. Annu. Rev. Immunol. 19: 291-330.
8. Rosmaraki, E. E., I. Douagi, C. Roth, F. Colucci, A. Cumano, and J. P. Di Santo. 2001. Identification of committed NK cell progenitors in adult murine bone marrow. Eur. J. Immunol. 31: 1900-1909.
9. Yokoyama, W. M., and B. F. Plougastel. 2003. Immune functions encoded by the natural killer gene complex. Nat Rev. Immunol. 3: 304-316.
10. Wang, J.-W., J. M. Howson, T. Ghansah, C. Desponts, J. M. Ninos, S. L. May, K. H. T. Nguyen, N. Toyama-Sorimachi, and W. G. Kerr. 2002. Influence of SHIP on the NK repertoire and allogeneic bone marrow transplantation. Science 295: 2094-2097.
11. Held, W., D. Cado, and D. Raulet. 1996. Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocompatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection. J. Exp. Med. 184: 2037-2041.
12. Lohoff, M., G. S, Duncan, D. Ferrick, H. W. Mittrucker, S. Bischof, S. Prechtl, M. Rollinghoff, E. Schmitt, A. Pahl, and T. W. Mak. 2000. Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type I cells. J. Exp. Med. 192: 325-336.
13. Kennedy, M. K., M. Glaccum, S. N. Brown, E. A. Butz, J. L. Viney, M. Embers, N. Matsuki, K. Charrier, L. Sedger, C. R. Willis, et al. 2000. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 191: 771-780.
14. Lodolce, J. P., D. L. Boone, S. Chai, R. E. Swain, T. Dassopoulos, S. Trettin, and A. Ma. 1998. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 9: 669-676.
15. Kawamura, T., R. Koka, A. Ma, and V. Kumar. 2003. Differential roles for IL-15Rα-chain in NK cell development and Ly-49 induction. J. Immunol. 171: 5085-5090.
16. Samson, S. I., O. Richard, M. Tavian, T. Ranson, C. A. Vosshenrich, F. Colucci, J. Buer, F. Grosveld, I. Godin, and J. P. Di Santo. 2003. GATA-3 promotes maturation, IFN-γ production, and liver-specific homing of NK cells. Immunity 19: 701-711.
17. Matsuyama, T., T. Kimura, M. Kitagawa, K. Pfeffer, T. Kawakami, N. Watanabe, T. M. Kundig, R. Amakawa, K. Kishihara, A. Wakeham, et al. 1993. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell 75: 83-97.
18. + dendritic cells in mice deficient for IFN regulatory factor-2. Proc. Natl. Acad. Sci. USA 101: 3909-3914.
19. Taki, S., T. Sato, K. Ogasawara, T. Fukuda, M. Sato, S. Hida, G. Suzuki, M. Mitsuyama, E. H. Shin, S. Kojima, et al. 1997. Multistage regulation of Th1-type immune responses by the transcription factor IRF-1. Immunity 6: 673-679.
20. Derby, E., V. Reddy, W. Kopp, E. Nelson, M. Baseler, T. Sayers, and A. Malyguine. 2001. Three-color flow cytometric assay for the study of the mechanisms of cell-mediated cytotoxicity. Immunol. Lett. 78: 35-39.
21. Long, E. O. 1999. Regulation of immune responses through inhibitory receptors. Annu. Rev. Immunol. 17: 875-904.
22. Raulet, D. H. 1999. Development and tolerance of natural killer cells. Curr. Opin. Immunol. 11: 129-134.
23. Hanke, T., H. Takizawa, C. W. McMahon, D. H. Busch, E. G. Pamer, J. D. Miller, I. D. Altman, Y. Liu, D. Cado, F. A. Lemonnier, et al. 1999. Direct assessment of MHC class 1 binding by seven Ly49 inhibitory NK cell receptors. Immunity 11: 67-77.
24. Salcedo, M., A. Diehl, M. Olsson-Alheim, J. Sundback, L. Van Kaer, K. Karre, and H. Ljunggren. 1997. Altered expression of Ly49 inhibitory receptors on natural killer cells from MHC class I-deficient mice. J. Immunol. 158: 3174-3180.
25. - mice. J. Immunol. 159: 5219-5225.
26. Hanke, T., H. Takizawa, and D. H. Raulet. 2001. MHC-dependent shaping of the inhibitory Ly49 receptor repertoire on NK cells: evidence for a regulated sequential model. Eur. J. Immunol. 31: 3370-3379.
27. Townsend, M. J., A. S. Weinmann, J. L. Matsuda, R. Salomon, P. J. Farnham, C. A. Biron, L. Gapin, and L. H. Glimcher. 2004. T-bet regulates the terminal maturation and homeostasis of NK and Vαl4i NKT cells. Immunity 20: 477-494.
28. Lowin-Kropf, B., and W. Held. 2000. Positive impact of inhibitory Ly49 receptor-MHC class I interaction on NK cell development. J. Immunol. 165: 91-95.
29. Held, W., B. Kunz, B. Lowin-Kropf, M. van de Wetering, and H. Clevers. 1999. Clonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1. Immunity 11: 433-442.
30. Colucci, F., S. I. Samson, R. P. DeKoter, O. Lantz, H. Singh, and J. P. Di Santo. 2001. Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells. Blood 97: 2625-2632.
31. Yokota, Y., A. Mansouri, S. Mori, S. Sugawara, S. Adachi, S. Nishikawa, and P. Gruss. 1999. Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature 397: 702-706.
32. Vosshenrich, C. A. J., T. Ranson, S. I. Samson, E. Corcuff, F. Colucci, E. E. Rosmaraki, and J. P. Di Santo. 2005. Roles for common cytokine receptor γ-chain-dependent cytokines in the generation, differentiation, and maturation of NK cell precursors and peripheral NK cells in vivo. J. Immunol. 174: 1213-1221.
33. Harada, H., M. Kitagawa, N. Tanaka, H. Yamamoto, K. Harada, M. Ishihara, and T. Taniguchi. 1993. Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2. Science 259: 971-974.
34. + T) cells, natural killer cells, and intestinal intraepithelial T cells. J. Exp. Med. 187: 967-972.
35. Ogasawara, K., S. Hida, N. Azimi, Y. Tagaya, T. Sato, T. Yokochi-Fukuda, T. A. Waldmann, T. Taniguchi, and S. Taki. 1998. Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature 391: 700-703.
36. Vaughan, P. S., F. Aziz, A. J. van Wijnen, S. Wu, H. Harada, T. Taniguchi, K. J. Soprano, J. L. Stein, and G. S. Stein. 1995. Activation of a cell-cycle-regulated histone gene by the oncogenic transcription factor IRF-2. Nature 377: 362-365.
37. Cuesta, N., C. A. Salkowski, K. E. Thomas, and S. N. Vogel. 2003. Regulation of lipopolysaccharide sensitivity by IFN regulatory factor-2. J. Immunol. 170: 5739-5747.
38. Lacorazza, H. D., Y. Miyazaki, A. Di Cristofano, A. Deblasio, C. Hedvat, J. Zhang, C. Cordon-Cardo, S. Mao, P. P. Pandolfi, and S. D. Nimer. 2002. The ETS protein MEF plays a critical role in perform gene expression and the development of natural killer and NK-T cells. Immunity 17: 437-449.
39. Barton, K., N. Mumusamy, C. Fischer, C. N. Ting, T. L. Walunas, L. L. Lanier, and J. M. Leiden. 1998. The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity 9: 555-563.