Cytokine-inducible CD40 expression in human endothelial cells is mediated by interferon regulatory factor-1

Blood

Volumn 99, Issue 2, 2002, Pages 520-525

  Wagner, Andreas H ^a   Gebauer, Matthias ^a   Pollok Kopp, Beatrix ^a   Hecker, Markus ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CD40 ANTIGEN; CD40 LIGAND; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; MESSENGER RNA; OLIGONUCLEOTIDE; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN EXPRESSION; ARTICLE; ATHEROSCLEROSIS; CHRONIC INFLAMMATION; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; ENDOTHELIUM CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; UMBILICAL VEIN; WESTERN BLOTTING;

EID: 0037079695     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.2.520     Document Type: Article

References (30)

1. CD40-CD40 ligand
2. The CD40/CD154 receptor/ligand dyad
3. Molecular and biological characterization of a murine ligand for CD40
4. CD40 and CD154 in cell-mediated immunity
5. Expression of functional CD40 by vascular endothelial cells
6. Functional interactions of T cells with endothelial cells: The role of CD40L-CD40-mediated signals
7. CD154 stimulation of interleukin-12 synthesis in human endothelial cells
8. Proinflammatory and immunoregulatory functions of interleukin-12
9. Macrophages, smooth muscle cells, endothelial cells, and T-cells express CD40 and CD154 in fatty streaks and more advanced human atherosclerotic lesions. Colocalization with epitopes of oxidized low-density lipoprotein, scavenger receptor, and CD16
10. CD40 signaling in vascular cells: A key role in atherosclerosis?
11. Reduction of atherosclerosis in mice by inhibition of CD40 signalling
12. Host CD40 ligand deficiency induces longterm allograft survival and donor-specific tolerance in mouse cardiac transplantation but does not prevent graft arteriosclerosis
13. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand
14. Differential regulation of CD40-mediated human B cell responses by antibodies directed against different CD40 epitopes
15. Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor KB and signal transducer and activation of transcription-1
16. Involvement of STAT-1 and ets family members in interferon-γ induction of CD40 transcription in microglia/macrophages
17. Identification of a silencer, enhancer, and basal promoter region in the human CD95 (Fas/APO-1) gene
18. Decoy oligodeoxynucleotide characterization of transcription factors controlling endothelin-B receptor expression in vascular smooth muscle cells
19. Hematopoietic inhibition by interferon-γ is partially mediated through interferon regulatory factor-1
20. Convergence of TNFα and IFNγ signalling pathways through synergistic induction of IRF-1/ISGF-2 is mediated by a composite GAS/KB promoter element
21. Regulation of the thrombotic potential of atheroma
22. CD40 and its ligand
23. Application of transcription factor "decoy" strategy as means of gene therapy and study of gene expression in cardiovascular disease
24. Therapeutic applications of transcription factor decoy oligonucleotides
25. CD40 on human endothelial cells: Inducibility by cytokines and functional regulation of adhesion molecule expression
26. Cytokine activation sensitizes human monocytic and endothelial cells to the cytotoxic effects of an anti-CD40 immunotoxin
27. Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for CD40-CD40 ligand signaling in atherosclerosis
28. Synergy between interferon-γ and tumor necrosis factor-α in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor KB
29. Matind and Matinspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data
30. Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-γ and TNF-α in oligodendrocytes