-
1
-
-
33847347313
-
ECM remodeling in hypertensive heart disease
-
Berk BC, Fujiwara K, Lehoux S. ECM remodeling in hypertensive heart disease. J Clin Invest. 2007;117:568-575.
-
(2007)
J Clin Invest
, vol.117
, pp. 568-575
-
-
Berk, B.C.1
Fujiwara, K.2
Lehoux, S.3
-
2
-
-
85047694494
-
A mechanistic role for cardiac myocyte apoptosis in heart failure
-
Wencker D, Chandra M, Nguyen K, Miao W, Garantziotis S, Factor SM, Shirani J, Armstrong RC, Kitsis RN. A mechanistic role for cardiac myocyte apoptosis in heart failure. J Clin Invest. 2003;111:1497-1504.
-
(2003)
J Clin Invest
, vol.111
, pp. 1497-1504
-
-
Wencker, D.1
Chandra, M.2
Nguyen, K.3
Miao, W.4
Garantziotis, S.5
Factor, S.M.6
Shirani, J.7
Armstrong, R.C.8
Kitsis, R.N.9
-
3
-
-
18644374460
-
Hop is an unusual homeobox gene that modulates cardiac development
-
Chen F, Kook H, Milewski R, Gitler AD, Lu MM, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay JP, Novotny J, Schwartz RJ, Harvey RP, Mullins MC, Epstein JA. Hop is an unusual homeobox gene that modulates cardiac development. Cell. 2002;110:713-723.
-
(2002)
Cell
, vol.110
, pp. 713-723
-
-
Chen, F.1
Kook, H.2
Milewski, R.3
Gitler, A.D.4
Lu, M.M.5
Li, J.6
Nazarian, R.7
Schnepp, R.8
Jen, K.9
Biben, C.10
Runke, G.11
MacKay, J.P.12
Novotny, J.13
Schwartz, R.J.14
Harvey, R.P.15
Mullins, M.C.16
Epstein, J.A.17
-
4
-
-
0035496099
-
Regulation of lymphocyte proliferation and death by FLIP
-
Thome M, Tschopp J. Regulation of lymphocyte proliferation and death by FLIP. Nat Rev Immunol. 2001;1:50-58.
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 50-58
-
-
Thome, M.1
Tschopp, J.2
-
5
-
-
0033781314
-
Cellular FLIP is expressed in cardiomyocytes and down-regulated in TUNEL-positive grafted cardiac tissues
-
Imanishi T, Murry CE, Reinecke H, Hano T, Nishio I, Liles WC, Hofsta L, Kim K, O'Brien KD, Schwartz SM, Han DK. Cellular FLIP is expressed in cardiomyocytes and down-regulated in TUNEL-positive grafted cardiac tissues. Cardiovasc Res. 2000;48:101-110.
-
(2000)
Cardiovasc Res
, vol.48
, pp. 101-110
-
-
Imanishi, T.1
Murry, C.E.2
Reinecke, H.3
Hano, T.4
Nishio, I.5
Liles, W.C.6
Hofsta, L.7
Kim, K.8
O'Brien, K.D.9
Schwartz, S.M.10
Han, D.K.11
-
6
-
-
0037230203
-
Alterations in apoptotic signaling in human idiopathic cardiomyopathic hearts in failure
-
Steenbergen C, Afshari CA, Petranka JG, Collins J, Martin K, Bennett L, Haugen A, Bushel P, Murphy E. Alterations in apoptotic signaling in human idiopathic cardiomyopathic hearts in failure. Am J Physiol Heart Circ Physiol. 2003;284:H268-H276.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
-
-
Steenbergen, C.1
Afshari, C.A.2
Petranka, J.G.3
Collins, J.4
Martin, K.5
Bennett, L.6
Haugen, A.7
Bushel, P.8
Murphy, E.9
-
7
-
-
0033662341
-
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
-
Yeh WC, Itie A, Elia AJ, Ng M, Shu HB, Wakeham A, Mirtsos C, Suzuki N, Bonnard M, Goeddel DV, Mak TW. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity. 2000;12:633-642.
-
(2000)
Immunity
, vol.12
, pp. 633-642
-
-
Yeh, W.C.1
Itie, A.2
Elia, A.J.3
Ng, M.4
Shu, H.B.5
Wakeham, A.6
Mirtsos, C.7
Suzuki, N.8
Bonnard, M.9
Goeddel, D.V.10
Mak, T.W.11
-
8
-
-
33750853831
-
Reduced myocarditis following Coxsackievirus infection in cellular FLICE inhibitory protein: Long form-transgenic mice
-
Huber S, Dohrman A, Sartini D, Budd RC. Reduced myocarditis following Coxsackievirus infection in cellular FLICE inhibitory protein: long form-transgenic mice. Immunology. 2006;119:541-550.
-
(2006)
Immunology
, vol.119
, pp. 541-550
-
-
Huber, S.1
Dohrman, A.2
Sartini, D.3
Budd, R.C.4
-
9
-
-
42049095914
-
C-Flip overexpression reduces cardiac hypertrophy in response to pressure overload
-
Giampietri C, Petrungaro S, Musumeci M, Coluccia P, Antonangeli F, De Cesaris P, Filippini A, Marano G, Ziparo E. c-Flip overexpression reduces cardiac hypertrophy in response to pressure overload. J Hypertens. 2008;26:1008-1016.
-
(2008)
J Hypertens
, vol.26
, pp. 1008-1016
-
-
Giampietri, C.1
Petrungaro, S.2
Musumeci, M.3
Coluccia, P.4
Antonangeli, F.5
De Cesaris, P.6
Filippini, A.7
Marano, G.8
Ziparo, E.9
-
10
-
-
74949112895
-
LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin/nuclear factor of activated T cells signaling
-
Bian ZY, Huang H, Jiang H, Shen DF, Yan L, Zhu LH, Wang L, Cao F, Liu C, Tang QZ, Li H. LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin/nuclear factor of activated T cells signaling. Hypertension. 2010;55:257-263.
-
(2010)
Hypertension
, vol.55
, pp. 257-263
-
-
Bian, Z.Y.1
Huang, H.2
Jiang, H.3
Shen, D.F.4
Yan, L.5
Zhu, L.H.6
Wang, L.7
Cao, F.8
Liu, C.9
Tang, Q.Z.10
Li, H.11
-
11
-
-
0027182438
-
Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts: Critical role of the AT1 receptor subtype
-
Sadoshima J, Izumo S. Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts: critical role of the AT1 receptor subtype. Circ Res. 1993;73: 413-423.
-
(1993)
Circ Res
, vol.73
, pp. 413-423
-
-
Sadoshima, J.1
Izumo, S.2
-
12
-
-
34247106590
-
Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction
-
Li HL, Zhuo ML, Wang D, Wang AB, Cai H, Sun LH, Yang Q, Huang Y, Wei YS, Liu PP, Liu DP, Liang CC. Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction. Circulation. 2007;115: 1885-1894.
-
(2007)
Circulation
, vol.115
, pp. 1885-1894
-
-
Li, H.L.1
Zhuo, M.L.2
Wang, D.3
Wang, A.B.4
Cai, H.5
Sun, L.H.6
Yang, Q.7
Huang, Y.8
Wei, Y.S.9
Liu, P.P.10
Liu, D.P.11
Liang, C.C.12
-
13
-
-
34848920368
-
TNF provokes car-diomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways
-
Haudek SB, Taffet GE, Schneider MD, Mann DL. TNF provokes car-diomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways. J Clin Invest. 2007;117:2692-2701.
-
(2007)
J Clin Invest
, vol.117
, pp. 2692-2701
-
-
Haudek, S.B.1
Taffet, G.E.2
Schneider, M.D.3
Mann, D.L.4
-
14
-
-
3242772151
-
Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs
-
Molkentin JD. Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs. Cardiovasc Res. 2004; 63:467-475.
-
(2004)
Cardiovasc Res
, vol.63
, pp. 467-475
-
-
Molkentin, J.D.1
-
15
-
-
0346095319
-
GIT1 functions as a scaffold for MEK1-tracellular signal-regulated kinase 1 and 2 activation by angiotensin II and epidermal growth factor
-
Yin G, Haendeler J, Yan C, Berk BC. GIT1 functions as a scaffold for MEK1-tracellular signal-regulated kinase 1 and 2 activation by angiotensin II and epidermal growth factor. Mol Cell Biol. 2004;24:875-885.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 875-885
-
-
Yin, G.1
Haendeler, J.2
Yan, C.3
Berk, B.C.4
-
16
-
-
33646591530
-
Requirement of Rac1 in the development of cardiac hypertrophy
-
Satoh M, Ogita H, Takeshita K, Mukai Y, Kwiatkowski DJ, Liao JK. Requirement of Rac1 in the development of cardiac hypertrophy. Proc Natl Acad Sci USA. 2006;103:7432-7437.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7432-7437
-
-
Satoh, M.1
Ogita, H.2
Takeshita, K.3
Mukai, Y.4
Kwiatkowski, D.J.5
Liao, J.K.6
-
17
-
-
33751558995
-
An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway
-
Nakajima A, Komazawa-Sakon S, Takekawa M, Sasazuki T, Yeh WC, Yagita H, Okumura K, Nakano H. An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway. EMBO J. 2006; 25:5549-5559.
-
(2006)
EMBO J
, vol.25
, pp. 5549-5559
-
-
Nakajima, A.1
Komazawa-Sakon, S.2
Takekawa, M.3
Sasazuki, T.4
Yeh, W.C.5
Yagita, H.6
Okumura, K.7
Nakano, H.8
-
18
-
-
0035051054
-
Cytoplasmic signaling pathways that regulate cardiac hypertrophy
-
Molkentin JD, Dorn GW II. Cytoplasmic signaling pathways that regulate cardiac hypertrophy. Annu Rev Physiol. 2001;63:391-426.
-
(2001)
Annu Rev Physiol
, vol.63
, pp. 391-426
-
-
Molkentin, J.D.1
Dorn, I.I.G.W.2
-
19
-
-
26244440041
-
Glycogen synthase kinase 3/3 inhibits myocardin-dependent transcription and hypertrophy induction through site-specific phosphorylation
-
Badorff C, Seeger FH, Zeiher AM, Dimmeler S. Glycogen synthase kinase 3/3 inhibits myocardin-dependent transcription and hypertrophy induction through site-specific phosphorylation. Circ Res. 2005;97: 645-654.
-
(2005)
Circ Res
, vol.97
, pp. 645-654
-
-
Badorff, C.1
Seeger, F.H.2
Zeiher, A.M.3
Dimmeler, S.4
-
20
-
-
0036172127
-
Fas receptor signaling inhibits glycogen synthase kinase 3 /3and induces cardiac hypertrophy following pressure overload
-
Badorff C, Ruetten H, Mueller S, Stahmer M, Gehring D, Jung F, Ihling C, Zeiher AM, Dimmeler S. Fas receptor signaling inhibits glycogen synthase kinase 3 /3and induces cardiac hypertrophy following pressure overload. J Clin Invest. 2002;109:373-381.
-
(2002)
J Clin Invest
, vol.109
, pp. 373-381
-
-
Badorff, C.1
Ruetten, H.2
Mueller, S.3
Stahmer, M.4
Gehring, D.5
Jung, F.6
Ihling, C.7
Zeiher, A.M.8
Dimmeler, S.9
-
21
-
-
33646076196
-
GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation
-
Xu J, Kimball TR, Lorenz JN, Brown DA, Bauskin AR, Klevitsky R, Hewett TE, Breit SN, Molkentin JD. GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circ Res. 2006;98:342-350.
-
(2006)
Circ Res
, vol.98
, pp. 342-350
-
-
Xu, J.1
Kimball, T.R.2
Lorenz, J.N.3
Brown, D.A.4
Bauskin, A.R.5
Klevitsky, R.6
Hewett, T.E.7
Breit, S.N.8
Molkentin, J.D.9
-
22
-
-
37849041966
-
Forkhead transcription factors and cardiovascular biology
-
Papanicolaou KN, Izumiya Y, Walsh K. Forkhead transcription factors and cardiovascular biology. Circ Res. 2008;102:16-31.
-
(2008)
Circ Res
, vol.102
, pp. 16-31
-
-
Papanicolaou, K.N.1
Izumiya, Y.2
Walsh, K.3
-
23
-
-
36048988646
-
Cardiac growth and angiogenesis coordinated by intertissue interactions
-
Walsh K, Shiojima I. Cardiac growth and angiogenesis coordinated by intertissue interactions. J Clin Invest. 2007;117:3176-3179.
-
(2007)
J Clin Invest
, vol.117
, pp. 3176-3179
-
-
Walsh, K.1
Shiojima, I.2
-
24
-
-
4043076222
-
Raf-1 kinase is required for cardiac hypertrophy and cardiomyocyte survival in response to pressure overload
-
Harris IS, Zhang S, Treskov I, Kovacs A, Weinheimer C, Muslin AJ. Raf-1 kinase is required for cardiac hypertrophy and cardiomyocyte survival in response to pressure overload. Circulation. 2004;110:718-723.
-
(2004)
Circulation
, vol.110
, pp. 718-723
-
-
Harris, I.S.1
Zhang, S.2
Treskov, I.3
Kovacs, A.4
Weinheimer, C.5
Muslin, A.J.6
-
25
-
-
14644414790
-
Protein kinase cascades in the regulation of cardiac hypertrophy
-
Dorn GW II, Force T. Protein kinase cascades in the regulation of cardiac hypertrophy. J Clin Invest. 2005;115:527-537.
-
(2005)
J Clin Invest
, vol.115
, pp. 527-537
-
-
Dorn, I.I.G.W.1
Force, T.2
-
26
-
-
33847695362
-
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 /3activity
-
Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T, Goettlicher M, Noppinger PR, Wurst W, Ferrari VA, Abrams CS, Gruber PJ, Epstein JA. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 /3activity. Nat Med. 2007;13:324-331.
-
(2007)
Nat Med
, vol.13
, pp. 324-331
-
-
Trivedi, C.M.1
Luo, Y.2
Yin, Z.3
Zhang, M.4
Zhu, W.5
Wang, T.6
Floss, T.7
Goettlicher, M.8
Noppinger, P.R.9
Wurst, W.10
Ferrari, V.A.11
Abrams, C.S.12
Gruber, P.J.13
Epstein, J.A.14
-
27
-
-
18744425429
-
The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways
-
Kataoka T, Budd RC, Holler N, Thome M, Martinon F, Irmler M, Burns K, Hahne M, Kennedy N, Kovacsovics M, Tschopp J. The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways. Curr Biol. 2000;10:640-648.
-
(2000)
Curr Biol
, vol.10
, pp. 640-648
-
-
Kataoka, T.1
Budd, R.C.2
Holler, N.3
Thome, M.4
Martinon, F.5
Irmler, M.6
Burns, K.7
Hahne, M.8
Kennedy, N.9
Kovacsovics, M.10
Tschopp, J.11
-
28
-
-
25844490942
-
The Fas-associated death domain protein/caspase-8/c-FLIP signaling pathway is involved in TNF-induced activation of ERK
-
Lüschen S, Falk M, Scherer G, Ussat S, Paulsen M, Adam-Klages S. The Fas-associated death domain protein/caspase-8/c-FLIP signaling pathway is involved in TNF-induced activation of ERK. Exp Cell Res. 2005;310: 33-42.
-
(2005)
Exp Cell Res
, vol.310
, pp. 33-42
-
-
Lüschen, S.1
Falk, M.2
Scherer, G.3
Ussat, S.4
Paulsen, M.5
Adam-Klages, S.6
-
29
-
-
0034795804
-
The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyo-cytes
-
Liang Q, Wiese RJ, Bueno OF, Dai YS, Markham BE, Molkentin JD. The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyo-cytes. Mol Cell Biol. 2001;21:7460-7469.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7460-7469
-
-
Liang, Q.1
Wiese, R.J.2
Bueno, O.F.3
Dai, Y.S.4
Markham, B.E.5
Molkentin, J.D.6
-
30
-
-
0034607819
-
Phosphorylation of GATA-4 is involved in a1-adrenergic agonist-responsive transcription of the endothelin-1 gene in cardiac myocytes
-
Morimoto T, Hasegawa K, Kaburagi S, Kakita T, Wada H, Yanazume T, Sasayama S. Phosphorylation of GATA-4 is involved in a1-adrenergic agonist-responsive transcription of the endothelin-1 gene in cardiac myocytes. J Biol Chem. 2000;275:13721-13726.
-
(2000)
J Biol Chem
, vol.275
, pp. 13721-13726
-
-
Morimoto, T.1
Hasegawa, K.2
Kaburagi, S.3
Kakita, T.4
Wada, H.5
Yanazume, T.6
Sasayama, S.7
-
31
-
-
23044435051
-
Recent advances in cardiac development with therapeutic implications for adult cardiovascular disease
-
Epstein JA, Parmacek MS. Recent advances in cardiac development with therapeutic implications for adult cardiovascular disease. Circulation. 2005;112:592-597.
-
(2005)
Circulation
, vol.112
, pp. 592-597
-
-
Epstein, J.A.1
Parmacek, M.S.2
-
32
-
-
34249283088
-
Overexpression of myofibrillogenesis regulator-1 aggravates cardiac hypertrophy induced by angiotensin II in mice
-
Li HL, She ZG, Li TB, Wang AB, Yang Q, Wei YS, Wang YG, Liu DP. Overexpression of myofibrillogenesis regulator-1 aggravates cardiac hypertrophy induced by angiotensin II in mice. Hypertension. 2007;49: 1399-1408.
-
(2007)
Hypertension
, vol.49
, pp. 1399-1408
-
-
Li, H.L.1
She, Z.G.2
Li, T.B.3
Wang, A.B.4
Yang, Q.5
Wei, Y.S.6
Wang, Y.G.7
Liu, D.P.8
-
33
-
-
33751104222
-
CAMP inhibits transforming growth factor-/3 -stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts
-
Liu X, Sun SQ, Hassid A, Ostrom RS. cAMP inhibits transforming growth factor-/3 -stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts. Mol Pharmacol. 2006;70:1992-2003.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1992-2003
-
-
Liu, X.1
Sun, S.Q.2
Hassid, A.3
Ostrom, R.S.4
|