-
1
-
-
84860398169
-
Food as exposure: Nutritional epigenetics and the new metabolism
-
Landecker, H. Food as exposure: Nutritional epigenetics and the new metabolism. Biosocieties 2011, 6, 167–194
-
(2011)
Biosocieties
, vol.6
, pp. 167-194
-
-
Landecker, H.1
-
2
-
-
84862539217
-
First dairying in green Saharan Africa in the fifth millennium BC
-
Dunne, J.; Evershed, R.P.; Salque, M.; Cramp, L.; Bruni, S.; Ryan, K.; Biagetti, S.; di Lernia, S. First dairying in green Saharan Africa in the fifth millennium BC. Nature 2012, 486, 390–394
-
(2012)
Nature
, vol.486
, pp. 390-394
-
-
Dunne, J.1
Evershed, R.P.2
Salque, M.3
Cramp, L.4
Bruni, S.5
Ryan, K.6
Biagetti, S.7
Di Lernia, S.8
-
3
-
-
84884185205
-
The milk revolution
-
Curry, A. The milk revolution. Nature 2013, 500, 20–22
-
(2013)
Nature
, vol.500
, pp. 20-22
-
-
Curry, A.1
-
4
-
-
60649108370
-
-
Food and Agriculture Organization of the United Nations, Food and Agriculture Organization of the United Nations: Roma, Italy
-
Food and Agriculture Organization of the United Nations. Food Outlook-Global Market Analysis; Food and Agriculture Organization of the United Nations: Roma, Italy, 2012; pp. 51–54
-
(2012)
Food Outlook-Global Market Analysis
, pp. 51-54
-
-
-
5
-
-
84938131796
-
-
Agriculture and Horticulture Development Board
-
Agriculture and Horticulture Development Board. Dairy Co. World dairy cow numbers. Available online: http://www.dairyco.org.uk/market-information/farming-data/cow-numbers/world-cownumbers/#. VTfift7-BW_ (assessed on 15 April 2015).
-
(2015)
Dairy Co. World Dairy Cow Numbers
-
-
-
6
-
-
84859778293
-
MTOR signaling in growth control and disease
-
Laplante, M.; Sabatini, D.M. mTOR signaling in growth control and disease. Cell 2012, 149, 274–293
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
8
-
-
84922789990
-
Nutrient-sensing mechanisms and pathways
-
Efeyan, A.; Comb, W.C.; Sabatini, D.M. Nutrient-sensing mechanisms and pathways. Nature 2015, 517, 302–310
-
(2015)
Nature
, vol.517
, pp. 302-310
-
-
Efeyan, A.1
Comb, W.C.2
Sabatini, D.M.3
-
9
-
-
84880912548
-
Milk is not just food but most likely a genetic transfection system activating mTORC1 signaling for postnatal growth
-
Melnik, B.C.; John, S.M.; Schmitz, G. Milk is not just food but most likely a genetic transfection system activating mTORC1 signaling for postnatal growth. Nutr. J. 2013, 12, 103
-
(2013)
Nutr. J
, vol.12
, pp. 103
-
-
Melnik, B.C.1
John, S.M.2
Schmitz, G.3
-
10
-
-
84856716614
-
Cow milk consumption, insulin-like growth factor-I, and human biology: A life history approach
-
Wiley, A.S. Cow milk consumption, insulin-like growth factor-I, and human biology: A life history approach. Am. J. Hum. Biol. 2012, 24, 130–138
-
(2012)
Am. J. Hum. Biol
, vol.24
, pp. 130-138
-
-
Wiley, A.S.1
-
11
-
-
84907255137
-
MicroRNAs are absorbed in biologically meaningful amounts from nutritionally relevant doses of cow milk and affect gene expression in peripheral blood mononuclear cells, HEK-293 kidney cell cultures, and mouse livers
-
Baier, S.R.; Nguyen, C.; Xie, F.; Wood, J.R.; Zempleni, J. MicroRNAs are absorbed in biologically meaningful amounts from nutritionally relevant doses of cow milk and affect gene expression in peripheral blood mononuclear cells, HEK-293 kidney cell cultures, and mouse livers. J. Nutr. 2014, 144, 1495–1500
-
(2014)
J. Nutr
, vol.144
, pp. 1495-1500
-
-
Baier, S.R.1
Nguyen, C.2
Xie, F.3
Wood, J.R.4
Zempleni, J.5
-
12
-
-
84863460204
-
Dissecting mammalian target of rapamycin to promote longevity
-
Mendelsohn, A.R.; Larrick, J.W. Dissecting mammalian target of rapamycin to promote longevity. Rejuvenation Res. 2012, 15, 334–337
-
(2012)
Rejuvenation Res
, vol.15
, pp. 334-337
-
-
Mendelsohn, A.R.1
Larrick, J.W.2
-
13
-
-
84916925703
-
MTOR signaling from cellular senescence to organismal aging
-
Xu, S.; Cai, Y.; Wie, Y. mTOR signaling from cellular senescence to organismal aging. Aging Dis. 2014, 5, 263–273
-
(2014)
Aging Dis
, vol.5
, pp. 263-273
-
-
Xu, S.1
Cai, Y.2
Wie, Y.3
-
14
-
-
84872527628
-
MTOR is a key modulator of ageing and age-related disease
-
Johnson, S.C.; Rabinovitch, P.S.; Kaeberlein, M. mTOR is a key modulator of ageing and age-related disease. Nature 2013, 493, 338–345
-
(2013)
Nature
, vol.493
, pp. 338-345
-
-
Johnson, S.C.1
Rabinovitch, P.S.2
Kaeberlein, M.3
-
15
-
-
84876869702
-
Potential role of FoxO1 and mTORC1 in the pathogenesis of Western diet-induced acne
-
Melnik, B.C.; Zouboulis, C.C. Potential role of FoxO1 and mTORC1 in the pathogenesis of Western diet-induced acne. Exp. Dermatol. 2013, 22, 311–315
-
(2013)
Exp. Dermatol
, vol.22
, pp. 311-315
-
-
Melnik, B.C.1
Zouboulis, C.C.2
-
16
-
-
78650510609
-
MTOR: From growth signal integration to cancer, diabetes and ageing
-
Zoncu, R.; Efeyan, A.; Sabatini, D.M. mTOR: From growth signal integration to cancer, diabetes and ageing. Nat. Rev. Mol. Cell Biol. 2011, 12, 21–35
-
(2011)
Nat. Rev. Mol. Cell Biol
, vol.12
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
-
17
-
-
84877927481
-
MTOR in aging, metabolism, and cancer
-
Cornu, M.; Albert, V.; Hall, M.N. mTOR in aging, metabolism, and cancer. Curr. Opin. Genet. Dev. 2013, 23, 53–62
-
(2013)
. Curr. Opin. Genet. Dev
, vol.23
, pp. 53-62
-
-
Cornu, M.1
Albert, V.2
Hall, M.N.3
-
18
-
-
84869413374
-
The role of mTOR signaling in Alzheimer disease
-
Oddo, S. The role of mTOR signaling in Alzheimer disease. Front. Biosci.2012, 4, 941–952
-
(2012)
Front. Biosci
, vol.4
, pp. 941-952
-
-
Oddo, S.1
-
19
-
-
84878422744
-
Mammalian target of rapamycin (MTor) mediates tau protein dyshomeostasis: Implication for Alzheimer disease
-
Tang, Z.; Bereczki, E.; Zhang, H.; Wang, S.; Li, C.; Ji, X.; Branca, R.M.; Lehtiö, J.; Guan, Z.; Filipcik, P.; et al. Mammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: Implication for Alzheimer disease. J. Biol. Chem. 2013, 288, 15556–15570
-
(2013)
J. Biol. Chem
, vol.288
, pp. 15556-15570
-
-
Tang, Z.1
Bereczki, E.2
Zhang, H.3
Wang, S.4
Li, C.5
Ji, X.6
Branca, R.M.7
Lehtiö, J.8
Guan, Z.9
Filipcik, P.10
-
20
-
-
84908425488
-
Milk intake and risk of mortality and fractures in women and men: Cohort studies
-
Michaëlsson, K.; Wolk, A.; Langenskiöld, S.; Basu, S.; Warensjö Lemming, E.; Melhus, H.; Byberg, L. Milk intake and risk of mortality and fractures in women and men: Cohort studies. BMJ 2014, 349, g6015
-
(2014)
BMJ
, vol.349
-
-
Michaëlsson, K.1
Wolk, A.2
Langenskiöld, S.3
Basu, S.4
Warensjö Lemming, E.5
Melhus, H.6
Byberg, L.7
-
21
-
-
77952007543
-
Mammalian target of rapamycin (MTOR): Conducting the cellular signaling symphony
-
Foster, K.G.; Fingar, D.C. Mammalian target of rapamycin (mTOR): Conducting the cellular signaling symphony. J. Biol. Chem. 2010, 285, 14071–14077
-
(2010)
J. Biol. Chem
, vol.285
, pp. 14071-14077
-
-
Foster, K.G.1
Fingar, D.C.2
-
22
-
-
14844363721
-
Signaling by target of rapamycin proteins in cell growth control
-
Inoki, K.; Ouyang, H.; Li, Y.; Guan, K.L. Signaling by target of rapamycin proteins in cell growth control. Microbiol. Mol. Biol. Rev. 2005, 69, 79–100
-
(2005)
Microbiol. Mol. Biol. Rev
, vol.69
, pp. 79-100
-
-
Inoki, K.1
Ouyang, H.2
Li, Y.3
Guan, K.L.4
-
23
-
-
65649128580
-
Amino acid regulation of TOR complex 1
-
Avruch, J.; Long, X.; Ortiz-Vega, S.; Rapley, J.; Papageorgiou, A.; Dai, N. Amino acid regulation of TOR complex 1. Am. J. Physiol. Endocrinol. Metab. 2009, 296, E592–E602
-
(2009)
Am. J. Physiol. Endocrinol. Metab
, vol.296
-
-
Avruch, J.1
Long, X.2
Ortiz-Vega, S.3
Rapley, J.4
Papageorgiou, A.5
Dai, N.6
-
24
-
-
78649348967
-
Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
-
Sengupta, S.; Peterson, T.; Sabatini, D.M. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol. Cell 2010, 40, 310–322
-
(2010)
Mol. Cell
, vol.40
, pp. 310-322
-
-
Sengupta, S.1
Peterson, T.2
Sabatini, D.M.3
-
26
-
-
79959409830
-
Amino acid signaling in TOR activation
-
Kim, J.; Guan, K.L. Amino acid signaling in TOR activation. Annu. Rev. Biochem. 2011, 80, 1001–1032
-
(2011)
Annu. Rev. Biochem
, vol.80
, pp. 1001-1032
-
-
Kim, J.1
Guan, K.L.2
-
27
-
-
84894486696
-
Nutrient regulation of the mTOR complex 1 signaling pathway
-
Kim, S.; Buel, G.R.; Blenis, J. Nutrient regulation of the mTOR complex 1 signaling pathway. Mol. Cells 2013, 35, 463–473
-
(2013)
Mol. Cells
, vol.35
, pp. 463-473
-
-
Kim, S.1
Buel, G.R.2
Blenis, J.3
-
28
-
-
84884676252
-
Nutrient signaling to mTOR and cell growth
-
Jewell, J.L.; Guan, K.L. Nutrient signaling to mTOR and cell growth. Trends Biochem. Sci. 2013, 38, 233–242
-
(2013)
Trends Biochem. Sci
, vol.38
, pp. 233-242
-
-
Jewell, J.L.1
Guan, K.L.2
-
29
-
-
84880544460
-
Nutrients and growth factors in mTORC1 activation
-
Efeyan, A.; Sabatini, D.M. Nutrients and growth factors in mTORC1 activation. Biochem. Soc. Trans. 2013, 41, 902–905
-
(2013)
Biochem. Soc. Trans
, vol.41
, pp. 902-905
-
-
Efeyan, A.1
Sabatini, D.M.2
-
30
-
-
84877965001
-
Regulation of mTORC1 and its impact on gene expression at a glance
-
Laplante, M.; Sabatini, D.M. Regulation of mTORC1 and its impact on gene expression at a glance. J. Cell Sci. 2013, 126, 1713–1719
-
(2013)
J. Cell Sci
, vol.126
, pp. 1713-1719
-
-
Laplante, M.1
Sabatini, D.M.2
-
31
-
-
66349138676
-
Nutrient control of mTORC1, a cell-cycle regulator
-
Wang, X.; Proud, C.G. Nutrient control of mTORC1, a cell-cycle regulator. Trends Cell Biol. 2009, 19, 260–267
-
(2009)
Trends Cell Biol
, vol.19
, pp. 260-267
-
-
Wang, X.1
Proud, C.G.2
-
32
-
-
77951166692
-
Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage
-
Chakrabarti, P.; English, T.; Shi, J.; Smas, C.M.; Kandror, K.V. Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage. Diabetes 2010, 59, 775–781
-
(2010)
Diabetes
, vol.59
, pp. 775-781
-
-
Chakrabarti, P.1
English, T.2
Shi, J.3
Smas, C.M.4
Kandror, K.V.5
-
33
-
-
84874655800
-
The multifaceted role of mTORC1 in the control of lipid metabolism
-
Ricoult, S.J.; Manning, B.D. The multifaceted role of mTORC1 in the control of lipid metabolism. EMBO Rep. 2013, 14, 242–251
-
(2013)
EMBO Rep
, vol.14
, pp. 242-251
-
-
Ricoult, S.J.1
Manning, B.D.2
-
34
-
-
84899003225
-
Long-term commercial cow’s milk consumption and its effects on metabolic parameters associated with obesity in young mice
-
Yamin, H.B.; Barnea, M.; Genzer, Y.; Chapnik, N.; Froy, O. Long-term commercial cow’s milk consumption and its effects on metabolic parameters associated with obesity in young mice. Mol. Nutr. Food Res. 2014, 58, 1061–1068
-
(2014)
Mol. Nutr. Food Res
, vol.58
, pp. 1061-1068
-
-
Yamin, H.B.1
Barnea, M.2
Genzer, Y.3
Chapnik, N.4
Froy, O.5
-
35
-
-
84880566446
-
A growing role for mTOR in promoting anabolic metabolism
-
Howell, J.J.; Ricoult, S.J.; Ben-Sahra, I.; Manning, B.D. A growing role for mTOR in promoting anabolic metabolism. Biochem. Soc. Trans. 2013, 41, 906–912
-
(2013)
Biochem. Soc. Trans
, vol.41
, pp. 906-912
-
-
Howell, J.J.1
Ricoult, S.J.2
Ben-Sahra, I.3
Manning, B.D.4
-
36
-
-
84880906852
-
Mechanistic target of rapamycin controls homeostasis of adipogenesis
-
Yoon, M.S.; Zhang, C.; Sun, Y.; Schoenherr, C.J.; Chen, J. Mechanistic target of rapamycin controls homeostasis of adipogenesis. J. Lipid Res. 2013, 54, 2166–2173
-
(2013)
J. Lipid Res
, vol.54
, pp. 2166-2173
-
-
Yoon, M.S.1
Zhang, C.2
Sun, Y.3
Schoenherr, C.J.4
Chen, J.5
-
37
-
-
84899709626
-
The role of mTORC1 in regulating protein synthesis and skeletal muscle mass in response to various mechanical stimuli
-
Goodman, C.A. The role of mTORC1 in regulating protein synthesis and skeletal muscle mass in response to various mechanical stimuli. Rev. Physiol. Biochem. Pharmacol. 2014, 166, 43–95
-
(2014)
Rev. Physiol. Biochem. Pharmacol
, vol.166
, pp. 43-95
-
-
Goodman, C.A.1
-
38
-
-
84927656380
-
The role of TORC1 in muscle development in Drosophila
-
Hatfield, I.; Harvey, I.; Yates, E.R.; Redd, J.R.; Reiter, L.T.; Bridges, D. The role of TORC1 in muscle development in Drosophila. Sci. Rep. 2015, 5, doi:10.1038/srep09676
-
(2015)
Sci. Rep
-
-
Hatfield, I.1
Harvey, I.2
Yates, E.R.3
Redd, J.R.4
Reiter, L.T.5
Bridges, D.6
-
39
-
-
84886628911
-
EIF4EBP3L acts as a gatekeeper of TORC1 in activity-dependent muscle growth by specifically regulating Mef2ca translational initiation
-
Yogev, O.; Williams, V.C.; Hinits, Y.; Hughes, S.M. eIF4EBP3L acts as a gatekeeper of TORC1 in activity-dependent muscle growth by specifically regulating Mef2ca translational initiation. PLoS Biol. 2013, 11, e1001679
-
(2013)
Plos Biol
, vol.11
-
-
Yogev, O.1
Williams, V.C.2
Hinits, Y.3
Hughes, S.M.4
-
40
-
-
84862083354
-
Cross-talk between AMPK and mTOR in regulating energy balance
-
Xu, J.; Ji, J.; Yan, X.H. Cross-talk between AMPK and mTOR in regulating energy balance. Crit. Rev. Food Sci. Nutr. 2012, 52, 373–381
-
(2012)
Crit. Rev. Food Sci. Nutr
, vol.52
, pp. 373-381
-
-
Xu, J.1
Ji, J.2
Yan, X.H.3
-
41
-
-
84862286951
-
Translational regulation in nutrigenomics
-
Liu, B.; Qian, S.B. Translational regulation in nutrigenomics. Adv. Nutr. 2011, 2, 511–519
-
(2011)
Adv. Nutr
, vol.2
, pp. 511-519
-
-
Liu, B.1
Qian, S.B.2
-
42
-
-
84893477830
-
Amino acids activate mammalian target of rapamycin (MTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging
-
Oshiro, N.; Rapley, J.; Avruch, J. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging. J. Biol. Chem.2014, 289, 2658–2674
-
(2014)
J. Biol. Chem
, vol.289
, pp. 2658-2674
-
-
Oshiro, N.1
Rapley, J.2
Avruch, J.3
-
44
-
-
84922727084
-
Metabolism. Differential regulation of mTORC1 by leucine and glutamine
-
Jewell, J.L.; Kim, Y.C.; Russell, R.C.; Yu, F.X.; Park, H.W.; Plouffe, S.W.; Tagliabracci, V.S.; Guan, K.L. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Science 2015, 347, 194–198
-
(2015)
Science
, vol.347
, pp. 194-198
-
-
Jewell, J.L.1
Kim, Y.C.2
Russell, R.C.3
Yu, F.X.4
Park, H.W.5
Plouffe, S.W.6
Tagliabracci, V.S.7
Guan, K.L.8
-
45
-
-
43549114054
-
Protein quality assessment: Impact of expanding understanding of protein and amino acid needs for optimal health
-
Millward, D.J.; Layman, D.K.; Tomé, D.; Schaafsma, G. Protein quality assessment: Impact of expanding understanding of protein and amino acid needs for optimal health. Am. J. Clin. Nutr. 2008, 87, 1576S–1581S.
-
(2008)
Am. J. Clin. Nutr
, vol.87
-
-
Millward, D.J.1
Layman, D.K.2
Tomé, D.3
Schaafsma, G.4
-
46
-
-
0031435501
-
Slow and fast dietary proteins differently modulate postprandial protein accretion
-
Boirie, Y.; Dangin, M.; Gachon, P.; Vasson M.P.; Maubois, J.L.; Beaufrère, B. Slow and fast dietary proteins differently modulate postprandial protein accretion. Proc. Natl. Acad. Sci. USA 1997, 94, 14930–14935
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14930-14935
-
-
Boirie, Y.1
Dangin, M.2
Gachon, P.3
Vasson, M.P.4
Maubois, J.L.5
Beaufrère, B.6
-
47
-
-
84898470784
-
Slow and fast dietary proteins differentially modulate postprandial metabolism
-
He, T.; Giuseppin, M.L. Slow and fast dietary proteins differentially modulate postprandial metabolism. Int. J. Food Sci. Nutr. 2014, 65, 386–390
-
(2014)
Int. J. Food Sci. Nutr
, vol.65
, pp. 386-390
-
-
He, T.1
Giuseppin, M.L.2
-
48
-
-
84878393788
-
Sequential releases of milk protein-derived bioactive peptides in the jejunum in healthy humans
-
Boutrou, R.; Gaudichon, C.; Dupont, D.; Jardin, J.; Airinei, G.; Marsset-Baglieri, A.; Benamouzig, R.; Tomé, D.; Leonil, J. Sequential releases of milk protein-derived bioactive peptides in the jejunum in healthy humans. Am. J. Clin. Nutr. 2013, 97, 1414–1423
-
(2013)
Am. J. Clin. Nutr
, vol.97
, pp. 1414-1423
-
-
Boutrou, R.1
Gaudichon, C.2
Dupont, D.3
Jardin, J.4
Airinei, G.5
Marsset-Baglieri, A.6
Benamouzig, R.7
Tomé, D.8
Leonil, J.9
-
49
-
-
0030010165
-
Gastrojejunal kinetics and the digestion of [15N]β-lactoglobulin and casein in humans: The influence of the nature and quantity of the protein
-
Mahé, S.; Roos, N.; Benamouzig, R.; Davin, L.; Luengo, C.; Gagnon, L.; Gaussergès, N.; Rautureau, J.; Tomé, D. Gastrojejunal kinetics and the digestion of [15N]β-lactoglobulin and casein in humans: The influence of the nature and quantity of the protein. Am. J. Clin. Nutr. 1996, 63, 546–552
-
(1996)
Am. J. Clin. Nutr
, vol.63
, pp. 546-552
-
-
Mahé, S.1
Roos, N.2
Benamouzig, R.3
Davin, L.4
Luengo, C.5
Gagnon, L.6
Gaussergès, N.7
Rautureau, J.8
Tomé, D.9
-
50
-
-
0023805814
-
Evolutionary traits in human milk proteins
-
Bounous, G.; Kongshavn, P.A.; Taveroff, A.; Gold, P. Evolutionary traits in human milk proteins. Med. Hypotheses 1988, 27, 133–140
-
(1988)
Med. Hypotheses
, vol.27
, pp. 133-140
-
-
Bounous, G.1
Kongshavn, P.A.2
Taveroff, A.3
Gold, P.4
-
51
-
-
0028321465
-
Amino acid composition of human milk is not unique
-
Davis, T.A.; Nguyen, H.V.; Garcia-Bravo, R.; Fiorotto, M.L.; Jackson, E.M.; Lewis, D.S.; Lee, D.R.; Reeds, P.J. Amino acid composition of human milk is not unique. J. Nutr. 1994, 124, 1126–1132
-
(1994)
J. Nutr
, vol.124
, pp. 1126-1132
-
-
Davis, T.A.1
Nguyen, H.V.2
Garcia-Bravo, R.3
Fiorotto, M.L.4
Jackson, E.M.5
Lewis, D.S.6
Lee, D.R.7
Reeds, P.J.8
-
52
-
-
59049087460
-
Bidirectional ransport of amino acids regulates mTOR and autophagy
-
Nicklin, P.; Bergman, P.; Zhang, B.; Triantafellow, E.; Wang, H.; Nyfeler, B.; Yang, H.; Hild, M.; Kung, C.; Wilson, C.; et al. Bidirectional ransport of amino acids regulates mTOR and autophagy. Cell 2009, 136, 521–534
-
(2009)
Cell
, vol.136
, pp. 521-534
-
-
Nicklin, P.1
Bergman, P.2
Zhang, B.3
Triantafellow, E.4
Wang, H.5
Nyfeler, B.6
Yang, H.7
Hild, M.8
Kung, C.9
Wilson, C.10
-
53
-
-
59049100116
-
An amino acid shuffle activates mTORC1
-
Cohen, A.; Hall, M.N. An amino acid shuffle activates mTORC1. Cell 2009, 136, 399–400
-
(2009)
Cell
, vol.136
, pp. 399-400
-
-
Cohen, A.1
Hall, M.N.2
-
54
-
-
84864931233
-
Glutaminolysis activates Rag-mTORC1 signaling
-
Duran, R.V.; Oppliger, W.; Robitaille, A.M.; Heiserich, L.; Skendaj, R.; Gottlieb, E.; Hall, M.N. Glutaminolysis activates Rag-mTORC1 signaling. Mol. Cell 2012, 47, 349–358
-
(2012)
Mol. Cell
, vol.47
, pp. 349-358
-
-
Duran, R.V.1
Oppliger, W.2
Robitaille, A.M.3
Heiserich, L.4
Skendaj, R.5
Gottlieb, E.6
Hall, M.N.7
-
55
-
-
84857804808
-
The structure and allosteric regulation of mammalian glutamate dehydrogenase
-
Li, M.; Li, C.; Allen, A.; Stanley, C.A.; Smith, T.J. The structure and allosteric regulation of mammalian glutamate dehydrogenase. Arch. Biochem. Biophys. 2012, 519, 69–80
-
(2012)
Arch. Biochem. Biophys
, vol.519
, pp. 69-80
-
-
Li, M.1
Li, C.2
Allen, A.3
Stanley, C.A.4
Smith, T.J.5
-
56
-
-
84880906805
-
Glutamate dehydrogenase contributes to leucine sensing in the regulation of autophagy
-
Lorin, S.; Tol, M.J.; Bauvy, C.; Strijland, A.; Poüs, C.; Verhoeven, A.J.; Codogno, P.; Meijer, A.J. Glutamate dehydrogenase contributes to leucine sensing in the regulation of autophagy. Autophagy 2013, 9, 850–860
-
(2013)
Autophagy
, vol.9
, pp. 850-860
-
-
Lorin, S.1
Tol, M.J.2
Bauvy, C.3
Strijland, A.4
Poüs, C.5
Verhoeven, A.J.6
Codogno, P.7
Meijer, A.J.8
-
57
-
-
0036787462
-
Metabolic and autocrine regulation of the mammalian target of rapamycin by pancreatic β-cells
-
McDaniel, M.L.; Marshall, C.A.; Pappan, K.L.; Kwon, G. Metabolic and autocrine regulation of the mammalian target of rapamycin by pancreatic β-cells. Diabetes 2002, 51, 2877–2885
-
(2002)
Diabetes
, vol.51
, pp. 2877-2885
-
-
McDaniel, M.L.1
Marshall, C.A.2
Pappan, K.L.3
Kwon, G.4
-
58
-
-
0035145602
-
Metabolic regulation by leucine of translation initiation through the mTOR-signaling pathway by pancreatic β-cells
-
Xu, G.; Kwon, G.; Cruz, W.S.; Marshall, C.A.; McDaniel, M.L. Metabolic regulation by leucine of translation initiation through the mTOR-signaling pathway by pancreatic β-cells. Diabetes 2001, 50, 353–360
-
(2001)
Diabetes
, vol.50
, pp. 353-360
-
-
Xu, G.1
Kwon, G.2
Cruz, W.S.3
Marshall, C.A.4
McDaniel, M.L.5
-
59
-
-
75049083587
-
Evaluation of a novel food composition database that includes glutamine and other amino acids derived from gene sequencing data
-
Lenders, C.M.; Liu, S.; Wilmore, D.W.; Sampson, L.; Dougherty, L.W.; Spiegelman, D.; Willett, W.C. Evaluation of a novel food composition database that includes glutamine and other amino acids derived from gene sequencing data. Eur. J. Clin. Nutr. 2009, 63, 1433–1439
-
(2009)
Eur. J. Clin. Nutr
, vol.63
, pp. 1433-1439
-
-
Lenders, C.M.1
Liu, S.2
Wilmore, D.W.3
Sampson, L.4
Dougherty, L.W.5
Spiegelman, D.6
Willett, W.C.7
-
60
-
-
84922743269
-
The amino acid transporter SLC38A9 is a key component of a lysosomal membrane complex that signals arginine sufficiency to mTORC1
-
Wang, S.; Tsun, Z.Y.; Wolfson, R.; Shen, K.; Wyant, G.A.; Plovanich, M.E.; Yuan, E.D.; Jones, T.D.; Chantranupong, L.; Comb, W.; et al. The amino acid transporter SLC38A9 is a key component of a lysosomal membrane complex that signals arginine sufficiency to mTORC1. Science 2015, 347, 188–194
-
(2015)
Science
, vol.347
, pp. 188-194
-
-
Wang, S.1
Tsun, Z.Y.2
Wolfson, R.3
Shen, K.4
Wyant, G.A.5
Plovanich, M.E.6
Yuan, E.D.7
Jones, T.D.8
Chantranupong, L.9
Comb, W.10
-
61
-
-
53549129190
-
The role of mTOR in the adaptation and failure of β-cells in type 2 diabetes
-
Leibowitz, G.; Cerasi, E.; Ketzinel-Gilad, M. The role of mTOR in the adaptation and failure of β-cells in type 2 diabetes. Diabetes Obes. Metab. 2008, 10, 157–169
-
(2008)
Diabetes Obes. Metab
, vol.10
, pp. 157-169
-
-
Leibowitz, G.1
Cerasi, E.2
Ketzinel-Gilad, M.3
-
62
-
-
77955890920
-
Leucine metabolism in regulation of insulin secretion from pancreatic β cells
-
Yang, J.; Chi, Y.; Burkhardt, B.R.; Guan, Y.; Wolf, B.A. Leucine metabolism in regulation of insulin secretion from pancreatic β cells. Nutr. Rev. 2010, 68, 270–279
-
(2010)
Nutr. Rev
, vol.68
, pp. 270-279
-
-
Yang, J.1
Chi, Y.2
Burkhardt, B.R.3
Guan, Y.4
Wolf, B.A.5
-
63
-
-
84874431540
-
MTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells
-
Le Bacquer, O.; Queniat, G.; Gmyr, V.; Kerr-Conte, J.; Lefebvre, B.; Pattou, F. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells. J. Endocrinol.2013, 216, 21–29
-
(2013)
J. Endocrinol
, vol.216
, pp. 21-29
-
-
Le Bacquer, O.1
Queniat, G.2
Gmyr, V.3
Kerr-Conte, J.4
Lefebvre, B.5
Pattou, F.6
-
64
-
-
0024388360
-
Protein intake in early infancy: Effects on plasma amino acid concentrations, insulin metabolism, and growth
-
Axelsson, I.E.; Ivarsson, S.A.; Räihä, N.C. Protein intake in early infancy: Effects on plasma amino acid concentrations, insulin metabolism, and growth. Pediatr. Res. 1989, 26, 614–617
-
(1989)
Pediatr. Res
, vol.26
, pp. 614-617
-
-
Axelsson, I.E.1
Ivarsson, S.A.2
Räihä, N.C.3
-
65
-
-
84879347250
-
Early diet impacts infant Rhesus gut microbiome, immunity, and metabolism
-
O’Sullivan, A.; He, X.; McNiven, E.M.; Haggarty, N.W.; Lönnerdal, B.; Slupsky, C.M. Early diet impacts infant Rhesus gut microbiome, immunity, and metabolism. J. Proteome Res. 2013, 12, 2833–2845
-
(2013)
J. Proteome Res
, vol.12
, pp. 2833-2845
-
-
O’Sullivan, A.1
He, X.2
McNiven, E.M.3
Haggarty, N.W.4
Lönnerdal, B.5
Slupsky, C.M.6
-
66
-
-
82355188280
-
Milk protein intake, the metabolic-endocrine response, and growth in infancy: Data from a randomized clinical trial
-
Socha, P.; Grote, V.; Gruszfeld, D.; Janas, R.; Demmelmair, H.; Closa-Monasterolo, R.; Subías, J.E.; Scaglioni, S.; Verduci, E.; Dain, E.; et al. Milk protein intake, the metabolic-endocrine response, and growth in infancy: Data from a randomized clinical trial. Am. J. Clin. Nutr. 2011, 94, 1776S–1784S.
-
(2011)
Am. J. Clin. Nutr
, vol.94
-
-
Socha, P.1
Grote, V.2
Gruszfeld, D.3
Janas, R.4
Demmelmair, H.5
Closa-Monasterolo, R.6
Subías, J.E.7
Scaglioni, S.8
Verduci, E.9
Dain, E.10
-
67
-
-
84926285465
-
The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus
-
Melnik, B.C. The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus. Curr. Diabetes Rev. 2015, 11, 46–62
-
(2015)
Curr. Diabetes Rev
, vol.11
, pp. 46-62
-
-
Melnik, B.C.1
-
68
-
-
1842301673
-
An insulin index of foods. The insulin demand generated by 1000-kK portions of common foods
-
Holt, S.; Brand Miller, J.; Petocz, P. An insulin index of foods. The insulin demand generated by 1000-kK portions of common foods. Am. J. Clin. Nutr. 1997, 66, 1264–1276
-
(1997)
Am. J. Clin. Nutr
, vol.66
, pp. 1264-1276
-
-
Holt, S.1
Brand Miller, J.2
Petocz, P.3
-
69
-
-
15944404633
-
Dissociation of the glycaemic and insulinaemic responses to whole and skimmed milk
-
Hoyt, G.; Hickey, M.S.; Cordain, L. Dissociation of the glycaemic and insulinaemic responses to whole and skimmed milk. Br. J. Nutr. 2005, 93, 175–177
-
(2005)
Br. J. Nutr
, vol.93
, pp. 175-177
-
-
Hoyt, G.1
Hickey, M.S.2
Cordain, L.3
-
70
-
-
15544362097
-
High intakes of milk, but not meat, increases s-insulin and insulin resistance in 8-year-old boys
-
Hoppe, C.; Mølgaard, C.; Vaag, A.; Barkholt, V.; Michaelsen, K.F. High intakes of milk, but not meat, increases s-insulin and insulin resistance in 8-year-old boys. Eur. J. Clin. Nutr. 2005, 59, 393–398
-
(2005)
Eur. J. Clin. Nutr
, vol.59
, pp. 393-398
-
-
Hoppe, C.1
Mølgaard, C.2
Vaag, A.3
Barkholt, V.4
Michaelsen, K.F.5
-
71
-
-
70249098802
-
Differential effects of casein versus whey on fasting plasma levels of insulin, IGF-1 and IGF-1/IGFBP-3: Results from a randomized 7-day supplementation study in prepubertal boys
-
Hoppe, C.; Mølgaard, C.; Dalum, C.; Vaag, A.; Michaelsen, K.F. Differential effects of casein versus whey on fasting plasma levels of insulin, IGF-1 and IGF-1/IGFBP-3: Results from a randomized 7-day supplementation study in prepubertal boys. Eur. J. Clin. Nutr. 2009, 63, 1076–1083
-
(2009)
Eur. J. Clin. Nutr
, vol.63
, pp. 1076-1083
-
-
Hoppe, C.1
Mølgaard, C.2
Dalum, C.3
Vaag, A.4
Michaelsen, K.F.5
-
72
-
-
0017818313
-
Selective release of gastric inhibitory polypeptide by intraduodenal amino acid perfusion in man
-
Thomas, F.B.; Sinar, D.; Mazzaferri, E.L.; Cataland, S.; Mekhjian, H.S.; Caldwell, J.H.; Fromkess, J.J. Selective release of gastric inhibitory polypeptide by intraduodenal amino acid perfusion in man. Gastroenterology 1978, 74, 1261–1265
-
(1978)
Gastroenterology
, vol.74
, pp. 1261-1265
-
-
Thomas, F.B.1
Sinar, D.2
Mazzaferri, E.L.3
Cataland, S.4
Mekhjian, H.S.5
Caldwell, J.H.6
Fromkess, J.J.7
-
73
-
-
60149100105
-
Dairy protein and leucine alter GLP-1 release and mRNA of genes involved in intestinal lipid metabolism in vitro
-
Chen, Q.; Reimer, R.A. Dairy protein and leucine alter GLP-1 release and mRNA of genes involved in intestinal lipid metabolism in vitro. Nutrition 2009, 25, 340–349
-
(2009)
Nutrition
, vol.25
, pp. 340-349
-
-
Chen, Q.1
Reimer, R.A.2
-
74
-
-
16544362066
-
Glycemia and insulinemia in healthy subjects after lactose-equivalent meals of milk and other food proteins: The role of plasma amino acids and incretins
-
Nilsson, M.; Stenberg, M.; Frid, A.H.; Holst, J.J.; Björck, I.M. Glycemia and insulinemia in healthy subjects after lactose-equivalent meals of milk and other food proteins: The role of plasma amino acids and incretins. Am. J. Clin. Nutr. 2004, 80, 1246–2353
-
(2004)
Am. J. Clin. Nutr
, vol.80
, pp. 1246-2353
-
-
Nilsson, M.1
Stenberg, M.2
Frid, A.H.3
Holst, J.J.4
Björck, I.M.5
-
75
-
-
34147133191
-
Metabolic effects of amino acid mixtures and whey protein in healthy subjects: Studies using glucose-equivalent drinks
-
Nilsson, M.; Holst, J.J.; Björck, I.M. Metabolic effects of amino acid mixtures and whey protein in healthy subjects: Studies using glucose-equivalent drinks. Am. J. Clin. Nutr. 2007, 85, 996–1004
-
(2007)
Am. J. Clin. Nutr
, vol.85
, pp. 996-1004
-
-
Nilsson, M.1
Holst, J.J.2
Björck, I.M.3
-
76
-
-
84861536072
-
The insulinogenic effects of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells
-
Salehi, A.; Gunnerud, U.; Muhammed, S.J.; Ostman, E.; Holst, J.J.; Björck, I.; Rorsman, P. The insulinogenic effects of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells. Nutr. Metab. 2012, 9, doi:10.1186/1743-7075-9-48
-
(2012)
Nutr. Metab
-
-
Salehi, A.1
Gunnerud, U.2
Muhammed, S.J.3
Ostman, E.4
Holst, J.J.5
Björck, I.6
Rorsman, P.7
-
77
-
-
84903980696
-
Exendin-4 stimulates islet cell replication via the IGF1 receptor activation of mTORC1/S6K1
-
Xie, J.; El Sayed, N.M.; Qi, C.; Zhao, X.; Moore, C.E.; Herbert, T.P. Exendin-4 stimulates islet cell replication via the IGF1 receptor activation of mTORC1/S6K1. J. Mol. Endocrinol. 2014, 53, 105–115
-
(2014)
J. Mol. Endocrinol
, vol.53
, pp. 105-115
-
-
Xie, J.1
El Sayed, N.M.2
Qi, C.3
Zhao, X.4
Moore, C.E.5
Herbert, T.P.6
-
78
-
-
84888310803
-
Serotonin regulates glucose-stimulated insulin secretion from pancreatic β cells during pregnancy
-
Ohara-Imaizumi, M.; Kim, H.; Yoshida, M.; Fujiwara, T.; Aoyagi, K.; Toyofuku, Y.; Nakamichi, Y.; Nishiwaki, C.; Okamura, T.; Uchida, T.; et al. Serotonin regulates glucose-stimulated insulin secretion from pancreatic β cells during pregnancy. Proc. Natl. Acad. Sci. USA 2013, 110, 19420–19425
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 19420-19425
-
-
Ohara-Imaizumi, M.1
Kim, H.2
Yoshida, M.3
Fujiwara, T.4
Aoyagi, K.5
Toyofuku, Y.6
Nakamichi, Y.7
Nishiwaki, C.8
Okamura, T.9
Uchida, T.10
-
79
-
-
84921697003
-
Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state
-
Kim, K.; Oh, C.M.; Ohara-Imaizumi, M.; Park, S.; Namkung, J.; Yadav, V.K.; Tamarina, N.A.; Roe, M.W.; Philipson, L.H.; Karsenty, G.; et al. Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state. Endocrinology 2015, 156, 444–452
-
(2015)
Endocrinology
, vol.156
, pp. 444-452
-
-
Kim, K.1
Oh, C.M.2
Ohara-Imaizumi, M.3
Park, S.4
Namkung, J.5
Yadav, V.K.6
Tamarina, N.A.7
Roe, M.W.8
Philipson, L.H.9
Karsenty, G.10
-
80
-
-
84903287572
-
Analysis of free ACh and 5-HT in milk from four different species and their bioactivity on 5-HT(3) and nACh receptors
-
Gallegos-Perez, J.L.; Limon, A.; Reyes-Ruiz, J.M.; Alshanqeeti, A.S.; Aljohi, M.A.; Miledi, R. Analysis of free ACh and 5-HT in milk from four different species and their bioactivity on 5-HT(3) and nACh receptors. Food Funct. 2014, 5, 1489–1494
-
(2014)
Food Funct
, vol.5
, pp. 1489-1494
-
-
Gallegos-Perez, J.L.1
Limon, A.2
Reyes-Ruiz, J.M.3
Alshanqeeti, A.S.4
Aljohi, M.A.5
Miledi, R.6
-
81
-
-
0032740212
-
Growth hormone and amino acid supply interact synergistically to control insulin-like growth factor-I production and gene expression in cultured ovine hepatocytes
-
Wheelhouse, N.M.; Stubbs, A.K.; Lomax, M.A.; MacRae, J.C.; Hazlerigg, D.G. Growth hormone and amino acid supply interact synergistically to control insulin-like growth factor-I production and gene expression in cultured ovine hepatocytes. J. Endocrinol. 1999, 163, 353–361
-
(1999)
J. Endocrinol
, vol.163
, pp. 353-361
-
-
Wheelhouse, N.M.1
Stubbs, A.K.2
Lomax, M.A.3
Macrae, J.C.4
Hazlerigg, D.G.5
-
82
-
-
0026085228
-
Nutrition and somatomedin. XXIII. Molecular regulation of IGF-I by amino acid availability in cultured hepatocytes
-
Harp, J.B.; Goldstein, S.; Phillips, L.S. Nutrition and somatomedin. XXIII. Molecular regulation of IGF-I by amino acid availability in cultured hepatocytes. Diabetes 1991, 40, 95–101
-
(1991)
Diabetes
, vol.40
, pp. 95-101
-
-
Harp, J.B.1
Goldstein, S.2
Phillips, L.S.3
-
83
-
-
0029745560
-
α-lactalbumin enriched low-protein infant formulas: A comparison to breast milk feeding
-
Heine, W.; Radke M.; Wutzke, K.D.; Peters, E.; Kundt, G. α-lactalbumin enriched low-protein infant formulas: A comparison to breast milk feeding. Acta Paediatr. 1996, 85, 1024–1028
-
(1996)
Acta Paediatr
, vol.85
, pp. 1024-1028
-
-
Heine, W.1
Radke, M.2
Wutzke, K.D.3
Peters, E.4
Kundt, G.5
-
84
-
-
0034085615
-
The bovine protein α-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress
-
Markus, C.R.; Olivier, B.; Panhuysen, G.E.; van der Gugten, J.; Alles, M.S.; Tuiten, A.; Westenberg, H.G.; Fekkes, D.; Koppeschaar, H.F.; de Haan, E.E. The bovine protein α-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress. Am. J. Clin. Nutr. 2000, 71, 1536–1544
-
(2000)
Am. J. Clin. Nutr
, vol.71
, pp. 1536-1544
-
-
Markus, C.R.1
Olivier, B.2
Panhuysen, G.E.3
Van Der Gugten, J.4
Alles, M.S.5
Tuiten, A.6
Westenberg, H.G.7
Fekkes, D.8
Koppeschaar, H.F.9
De Haan, E.E.10
-
85
-
-
77951453523
-
Milk consumption and circulating insulin-like growth factor-I level: A systematic literature review
-
Qin, L.Q.; He, K.; Xu, J.Y. Milk consumption and circulating insulin-like growth factor-I level: A systematic literature review. Int. J. Food Sci. Nutr. 2009, 60, 330–340
-
(2009)
Int. J. Food Sci. Nutr
, vol.60
, pp. 330-340
-
-
Qin, L.Q.1
He, K.2
Xu, J.Y.3
-
86
-
-
33845519394
-
Diet, serum insulin-like growth factor-I and IGF-binding protein-3 in European women
-
Norat, T.; Dossus, L.; Rinaldi, S.; Overvad, K.; Grønbaek, H.; Tjønneland, A.; Olsen, A.; Clavel-Chapelon, F.; Boutron-Ruault, M.C.; Boeing, H.; et al. Diet, serum insulin-like growth factor-I and IGF-binding protein-3 in European women. Eur. J. Clin. Nutr. 2007, 61, 91–98
-
(2007)
Eur. J. Clin. Nutr
, vol.61
, pp. 91-98
-
-
Norat, T.1
Dossus, L.2
Rinaldi, S.3
Overvad, K.4
Grønbaek, H.5
Tjønneland, A.6
Olsen, A.7
Clavel-Chapelon, F.8
Boutron-Ruault, M.C.9
Boeing, H.10
-
87
-
-
36749066755
-
Milk consumption and the prepubertal somatotropic axis
-
Rich-Edwards, J.W.; Ganmaa, D.; Pollak, M.N.; Nakamoto, E.K.; Kleinman, K.; Tserendolgor, U.; Willett, W.C.; Frazier, A.L. Milk consumption and the prepubertal somatotropic axis. Nutr. J. 2007, 6, doi:10.1186/1475-2891-6-28
-
(2007)
Nutr. J
-
-
Rich-Edwards, J.W.1
Ganmaa, D.2
Pollak, M.N.3
Nakamoto, E.K.4
Kleinman, K.5
Tserendolgor, U.6
Willett, W.C.7
Frazier, A.L.8
-
88
-
-
84900835458
-
Effect of milk proteins on linear growth and IGF variables in overweight adolescents
-
Larnkjær, A.; Arnberg, K.; Michaelsen, K.F.; Jensen, S.M.; Mølgaard, C. Effect of milk proteins on linear growth and IGF variables in overweight adolescents. Growth Horm. IGF Res. 2014, 24, 54–59
-
(2014)
Growth Horm. IGF Res
, vol.24
, pp. 54-59
-
-
Larnkjær, A.1
Arnberg, K.2
Michaelsen, K.F.3
Jensen, S.M.4
Mølgaard, C.5
-
89
-
-
84866128888
-
Leucine signaling in the pathogenesis of type 2 diabetes and obesity
-
Melnik, B.C. Leucine signaling in the pathogenesis of type 2 diabetes and obesity. World J. Diabetes 2012, 3, 38–53
-
(2012)
World J. Diabetes
, vol.3
, pp. 38-53
-
-
Melnik, B.C.1
-
90
-
-
84911090935
-
Glutamine stimulates biosynthesis and secretion of insulin-like growth factor 2 (IGF2), an autocrine regulator of β cell mass and function
-
Modi, H.; Cornu, M.; Thorens, B. Glutamine stimulates biosynthesis and secretion of insulin-like growth factor 2 (IGF2), an autocrine regulator of β cell mass and function. J. Biol. Chem. 2014, 289, 31972–31982
-
(2014)
J. Biol. Chem
, vol.289
, pp. 31972-31982
-
-
Modi, H.1
Cornu, M.2
Thorens, B.3
-
91
-
-
84908192544
-
The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation
-
Csibi, A.; Lee, G.; Yoon, S.O.; Tong, H.; Ilter, D.; Elia, I.; Fendt, S.M.; Roberts, T.M.; Blenis, J. The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation. J. Curr. Biol. 2014, 24, 2274–2280
-
(2014)
J. Curr. Biol
, vol.24
, pp. 2274-2280
-
-
Csibi, A.1
Lee, G.2
Yoon, S.O.3
Tong, H.4
Ilter, D.5
Elia, I.6
Fendt, S.M.7
Roberts, T.M.8
Blenis, J.9
-
92
-
-
84899028213
-
Fatty acids are novel nutrient factors to regulate mTORC1 lysosomal localization and apoptosis in podocytes
-
Yasuda, M.; Tanaka, Y.; Kume, S.; Morita, Y.; Chin-Kanasaki, M.; Araki, H.; Isshiki, K.; Araki, S.; Koya, D.; Haneda, M.; et al. Fatty acids are novel nutrient factors to regulate mTORC1 lysosomal localization and apoptosis in podocytes. Biochim. Biophys. Acta 2014, 1842, 1097–1108
-
(2014)
Biochim. Biophys. Acta
, vol.1842
, pp. 1097-1108
-
-
Yasuda, M.1
Tanaka, Y.2
Kume, S.3
Morita, Y.4
Chin-Kanasaki, M.5
Araki, H.6
Isshiki, K.7
Araki, S.8
Koya, D.9
Haneda, M.10
-
93
-
-
34548092167
-
Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes
-
Mordier, S.; Iynedjian, P.B. Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes. Biochem. Biophys. Res. Commun. 2007, 362, 206–211
-
(2007)
Biochem. Biophys. Res. Commun
, vol.362
, pp. 206-211
-
-
Mordier, S.1
Iynedjian, P.B.2
-
94
-
-
77958149976
-
Palmitate induced insulin resistance by PKCtheta-dependent activation of mTOR/S6K pathway in C2C12 myotubes
-
Wang, X.; Yu, W.; Nawaz, A.; Guan, F.; Sun, S.; Wang, C. Palmitate induced insulin resistance by PKCtheta-dependent activation of mTOR/S6K pathway in C2C12 myotubes. Exp. Clin. Endocrinol. Diabetes 2010, 118, 657–661
-
(2010)
Exp. Clin. Endocrinol. Diabetes
, vol.118
, pp. 657-661
-
-
Wang, X.1
Yu, W.2
Nawaz, A.3
Guan, F.4
Sun, S.5
Wang, C.6
-
95
-
-
84907485622
-
Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway
-
Hatanaka, M.; Maier, B.; Sims, E.K.; Templin, A.T.; Kulkarni, R.N.; Evans-Molina, C.; Mirmira, R.G. Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway. Diabetes 2014, 63, 3404–3415
-
(2014)
Diabetes
, vol.63
, pp. 3404-3415
-
-
Hatanaka, M.1
Maier, B.2
Sims, E.K.3
Templin, A.T.4
Kulkarni, R.N.5
Evans-Molina, C.6
Mirmira, R.G.7
-
96
-
-
84927636713
-
Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection
-
Pardo, V.; González-Rodríguez, Á.; Muntané, J.; Kozma, S.C.; Valverde, Á.M. Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection. Food Chem. Toxicol. 2015, 80, 298–309
-
(2015)
Food Chem. Toxicol
, vol.80
, pp. 298-309
-
-
Pardo, V.1
González-Rodríguez, Á.2
Muntané, J.3
Kozma, S.C.4
Valverde, M.5
-
97
-
-
33744505375
-
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
-
Um, S.H.; D’Alessio, D.; Thomas, G. Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metab. 2006, 3, 393–402
-
(2006)
Cell Metab
, vol.3
, pp. 393-402
-
-
Um, S.H.1
D’Alessio, D.2
Thomas, G.3
-
99
-
-
0025427484
-
Changes in milk fat phospholipids during lactation
-
Bitman, J.; Wood, D.L. Changes in milk fat phospholipids during lactation. J. Dairy Sci. 1990, 73, 1208–1216
-
(1990)
J. Dairy Sci
, vol.73
, pp. 1208-1216
-
-
Bitman, J.1
Wood, D.L.2
-
100
-
-
34249302620
-
Exosome-mediated transfer of mRNA and microRNAs is novel mechanism of genetic exchange between cells
-
Valadi, H.; Ekstöm, K.; Bossios, A.; Sjöstrand, M.; Lee, J.J.; Lötvall, J.O. Exosome-mediated transfer of mRNA and microRNAs is novel mechanism of genetic exchange between cells. Nat. Cell Biol.2007, 9, 654–659
-
(2007)
Nat. Cell Biol
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekstöm, K.2
Bossios, A.3
Sjöstrand, M.4
Lee, J.J.5
Lötvall, J.O.6
-
101
-
-
84867605356
-
Regulation of mammalian gene expression by exogeneous microRNAs
-
Liang, H.; Huang, L.; Cao, J.; Zen, K.; Chen, X.; Zhang C.Y. Regulation of mammalian gene expression by exogeneous microRNAs. Wiley Interdiscip. Rev. RNA 2012, 3, 733–742
-
(2012)
Wiley Interdiscip. Rev. RNA
, vol.3
, pp. 733-742
-
-
Liang, H.1
Huang, L.2
Cao, J.3
Zen, K.4
Chen, X.5
Zhang, C.Y.6
-
102
-
-
84862777377
-
Secreted microRNAs: A new form of intercellular communication
-
Chen, X.; Liang, H.; Zhang, J.; Zen, K.; Thang, C.Y. Secreted microRNAs: A new form of intercellular communication. Trends Cell Biol. 2012, 22, 125–132
-
(2012)
Trends Cell Biol
, vol.22
, pp. 125-132
-
-
Chen, X.1
Liang, H.2
Zhang, J.3
Zen, K.4
Thang, C.Y.5
-
103
-
-
83555173384
-
Exosomes: Small vesicles participating in intercellular communication
-
Ludwig, A.K.; Giebel, B. Exosomes: Small vesicles participating in intercellular communication. Int. J. Biochem. Cell Biol. 2012, 44, 11–15
-
(2012)
Int. J. Biochem. Cell Biol
, vol.44
, pp. 11-15
-
-
Ludwig, A.K.1
Giebel, B.2
-
104
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros, V. The functions of animal microRNAs. Nature 2004, 431, 350–355
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
105
-
-
84862169420
-
Horizontal transfer of microRNAs: Molecular mechanism and clinical applications
-
Chen, X.; Liang, H.; Zhang, J.; Zen, K.; Zhang, C.Y. Horizontal transfer of microRNAs: Molecular mechanism and clinical applications. Protein Cell 2012, 3, 28–37
-
(2012)
Protein Cell
, vol.3
, pp. 28-37
-
-
Chen, X.1
Liang, H.2
Zhang, J.3
Zen, K.4
Zhang, C.Y.5
-
106
-
-
78149484489
-
The microRNA spectrum in 12 body fluids
-
Weber, J.A.; Baxter, D.H.; Zhang, S.; Huang, D.Y.; Huang, K.H.; Lee, M.J.; Galas, D.J.; Wang, K. The microRNA spectrum in 12 body fluids. Clin. Chem. 2010, 56, 1733–1741
-
(2010)
Clin. Chem
, vol.56
, pp. 1733-1741
-
-
Weber, J.A.1
Baxter, D.H.2
Zhang, S.3
Huang, D.Y.4
Huang, K.H.5
Lee, M.J.6
Galas, D.J.7
Wang, K.8
-
107
-
-
84856321323
-
Bovine milk exosome proteome
-
Reinhardt, T.A.; Lippolis, J.D.; Nonnecke, B.J.; Sacco, R.E. Bovine milk exosome proteome. J. Proteomics 2012, 75, 1486–1492
-
(2012)
J. Proteomics
, vol.75
, pp. 1486-1492
-
-
Reinhardt, T.A.1
Lippolis, J.D.2
Nonnecke, B.J.3
Sacco, R.E.4
-
108
-
-
77952745080
-
Isolation of bovine milk-derived microvesicles carrying mRNAs and microRNAs
-
Hata, T.; Murakami, K.; Nakatani, H.; Yamamoto, Y.; Matsuda, T.; Aoki, N. Isolation of bovine milk-derived microvesicles carrying mRNAs and microRNAs. Biochem. Biophys. Res. Commun. 2010, 396, 528–533
-
(2010)
Biochem. Biophys. Res. Commun
, vol.396
, pp. 528-533
-
-
Hata, T.1
Murakami, K.2
Nakatani, H.3
Yamamoto, Y.4
Matsuda, T.5
Aoki, N.6
-
109
-
-
84924848122
-
Purification of RNA from milk whey
-
Izumi, H.; Kosaka, N.; Shimizu, T.; Sekine, K.; Ochiya, T.; Takase, M. Purification of RNA from milk whey. Methods Mol. Biol. 2013, 1024, 191–201
-
(2013)
Methods Mol. Biol
, vol.1024
, pp. 191-201
-
-
Izumi, H.1
Kosaka, N.2
Shimizu, T.3
Sekine, K.4
Ochiya, T.5
Takase, M.6
-
110
-
-
84928056582
-
Bovine milk exosomes contain microRNA and mRNA and are taken up by human macrophages
-
Izumi, H.; Tsuda, M.; Sato, Y.; Kosaka, N.; Ochiya, T.; Iwamoto, H.; Namba, K.; Takeda Y. Bovine milk exosomes contain microRNA and mRNA and are taken up by human macrophages. J. Dairy Sci. 2015, 98, 2920–2933
-
(2015)
J. Dairy Sci
, vol.98
, pp. 2920-2933
-
-
Izumi, H.1
Tsuda, M.2
Sato, Y.3
Kosaka, N.4
Ochiya, T.5
Iwamoto, H.6
Namba, K.7
Takeda, Y.8
-
111
-
-
84926311639
-
Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β
-
Pieters, B.C.; Arntz, O.J.; Bennink, M.B.; Broeren, M.G.; van Caam, A.P.; Koenders, M.I.; van Lent, P.L.; van den Berg, W.B.; de Vries, M.; van der Kraan, P.M.; et al. Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β. PLoS ONE 2015, 10, e0121123
-
(2015)
Plos ONE
, vol.10
-
-
Pieters, B.C.1
Arntz, O.J.2
Bennink, M.B.3
Broeren, M.G.4
Van Caam, A.P.5
Koenders, M.I.6
Van Lent, P.L.7
Van Den Berg, W.B.8
De Vries, M.9
Van Der Kraan, P.M.10
-
112
-
-
84874819067
-
Immune modulatory function of abundant immune-related microRNAs in microvesicles from bovine colostrum
-
Sun, Q.; Chen, X.; Yu, J.; Zen, K.; Zhang, C.Y.; Li, L. Immune modulatory function of abundant immune-related microRNAs in microvesicles from bovine colostrum. Protein Cell 2013, 4, 197–210
-
(2013)
Protein Cell
, vol.4
, pp. 197-210
-
-
Sun, Q.1
Chen, X.2
Yu, J.3
Zen, K.4
Zhang, C.Y.5
Li, L.6
-
113
-
-
77957037314
-
MicroRNA as a new immune-regulatory agent in breast milk
-
Kosaka, N.; Izumi, H.; Sekine, K.; Ochiya, T. microRNA as a new immune-regulatory agent in breast milk. Silence 2010, 1, doi:10.1186/1758-907X-1-7
-
(2010)
Silence
-
-
Kosaka, N.1
Izumi, H.2
Sekine, K.3
Ochiya, T.4
-
114
-
-
83655181807
-
Immune-related microRNAs are abundant in breast milk exosomes
-
Zhou, Q.; Li, M.; Wang, X.; Li, Q.; Wang, T.; Zhu, Q.; Zhou, X.; Wang, X.; Gao, X.; Li, X. Immune-related microRNAs are abundant in breast milk exosomes. Int. J. Biol. Sci. 2012, 8, 118–123
-
(2012)
Int. J. Biol. Sci
, vol.8
, pp. 118-123
-
-
Zhou, Q.1
Li, M.2
Wang, X.3
Li, Q.4
Wang, T.5
Zhu, Q.6
Zhou, X.7
Wang, X.8
Gao, X.9
Li, X.10
-
115
-
-
84894246742
-
Milk: An exosomal microRNA transmitter promoting thymic regulatory T cell maturation preventing the development of atopy?
-
Melnik, B.C.; John, S.M.; Schmitz, G. Milk: An exosomal microRNA transmitter promoting thymic regulatory T cell maturation preventing the development of atopy? J. Transl. Med. 2014, 12, doi:10.1186/1479-5876-12-43
-
(2014)
J. Transl. Med
-
-
Melnik, B.C.1
John, S.M.2
Schmitz, G.3
-
116
-
-
84924968733
-
Immunomodulatory role of microRNAs transferred by extracellular vesicles
-
Fernández-Messina, L.; Gutiérrez-Vázquez, C.; Rivas-García, E.; Sánchez-Madrid, F.; de la Fuente, H. Immunomodulatory role of microRNAs transferred by extracellular vesicles. Biol. Cell 2015, 107, 61–77
-
(2015)
Biol. Cell
, vol.107
, pp. 61-77
-
-
Fernández-Messina, L.1
Gutiérrez-Vázquez, C.2
Rivas-García, E.3
Sánchez-Madrid, F.4
De La Fuente, H.5
-
117
-
-
77957567010
-
Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products
-
Chen, X.; Gao, C.; Li, H.; Huang, L.; Sun, Q.; Dong, Y.; Guan, D.; Hu, X.; Zhao, S.; Li, L.; et al. Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products. Cell Res. 2010, 20, 1128–1137
-
(2010)
Cell Res
, vol.20
, pp. 1128-1137
-
-
Chen, X.1
Gao, C.2
Li, H.3
Huang, L.4
Sun, Q.5
Dong, Y.6
Guan, D.7
Hu, X.8
Zhao, S.9
Li, L.10
-
118
-
-
84865339380
-
Bovine milk contains microRNA and messenger RNA that are stable under degradative conditions
-
Izumi, H.; Kosaka, N.; Shimizu, T.; Sekine, K.; Ochiya, T.; Takase, M. Bovine milk contains microRNA and messenger RNA that are stable under degradative conditions. J. Dairy Sci. 2012, 95, 4831–4841
-
(2012)
J. Dairy Sci
, vol.95
, pp. 4831-4841
-
-
Izumi, H.1
Kosaka, N.2
Shimizu, T.3
Sekine, K.4
Ochiya, T.5
Takase, M.6
-
119
-
-
84921450272
-
Loss of miRNAs during processing and storage of cow’s (Bos taurus) milk
-
Howard, K.M.; Jati Kusuma, R.; Baier, S.R.; Friemel, T.; Markham, L.; Vanamala, J.; Zempleni, J. Loss of miRNAs during processing and storage of cow’s (Bos taurus) milk. J. Agric. Food Chem. 2015, 63, 588–592
-
(2015)
J. Agric. Food Chem
, vol.63
, pp. 588-592
-
-
Howard, K.M.1
Jati Kusuma, R.2
Baier, S.R.3
Friemel, T.4
Markham, L.5
Vanamala, J.6
Zempleni, J.7
-
120
-
-
31544458134
-
Branched-chain amino acids: Enzyme and substrate regulation
-
Brosnan, J.T.; Brosnan, M.E. Branched-chain amino acids: Enzyme and substrate regulation. J. Nutr. 2006, 136, 207S–211S.
-
(2006)
J. Nutr
, vol.136
-
-
Brosnan, J.T.1
Brosnan, M.E.2
-
121
-
-
73649126526
-
Branched-chain amino acid metabolon: Interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm)
-
Islam, M.M.; Nautiyal, M.; Wynn, R.M.; Mobley, J.A.; Chuang, D.T.; Hutson, S.M. Branched-chain amino acid metabolon: Interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm). J. Biol. Chem.2010, 285, 265–276
-
(2010)
J. Biol. Chem
, vol.285
, pp. 265-276
-
-
Islam, M.M.1
Nautiyal, M.2
Wynn, R.M.3
Mobley, J.A.4
Chuang, D.T.5
Hutson, S.M.6
-
122
-
-
0034653468
-
Crystal structure of human branched-chain α-ketoacid dehydrogenase and the molecular basis of multienzyme complex deficiency in maple syrup urine disease
-
AEvarsson, A.; Chuang, J.L.; Wynn, R.M.; Turley, S.; Chuang, D.T.; Hol, W.G. Crystal structure of human branched-chain α-ketoacid dehydrogenase and the molecular basis of multienzyme complex deficiency in maple syrup urine disease. Structure 2000, 8, 277–291
-
(2000)
Structure
, vol.8
, pp. 277-291
-
-
Aevarsson, A.1
Chuang, J.L.2
Wynn, R.M.3
Turley, S.4
Chuang, D.T.5
Hol, W.G.6
-
123
-
-
27944480498
-
Human microRNA (MiR29b) expression controls the amount of branched chain α ketoacid dehydrogenase complex in a cell
-
Mersey, B.D.; Jin, P.; Danner, D.J. Human microRNA (miR29b) expression controls the amount of branched chain α ketoacid dehydrogenase complex in a cell. Hum. Mol. Genet.2005, 14, 3371–3377
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 3371-3377
-
-
Mersey, B.D.1
Jin, P.2
Danner, D.J.3
-
124
-
-
84929773810
-
Epigenetic regulation of miR-29s affects the lactation activity of dairy cow mammary epithelial cells
-
Bian, Y.; Lei, Y.; Wang, C.; Wang, J.; Wang, L.; Liu, L.; Liu, L.; Gao, X.; Li, Q. Epigenetic regulation of miR-29s affects the lactation activity of dairy cow mammary epithelial cells. J. Cell. Physiol. 2015, 230, 2152–2163
-
(2015)
J. Cell. Physiol
, vol.230
, pp. 2152-2163
-
-
Bian, Y.1
Lei, Y.2
Wang, C.3
Wang, J.4
Wang, L.5
Liu, L.6
Liu, L.7
Gao, X.8
Li, Q.9
-
125
-
-
0029086245
-
Expression and characterization of branched-chain α-ketoacid dehydrogenase kinase from the rat. Is it a histidine-protein kinase?
-
Davie, J.R.; Wynn, R.M.; Meng, M.; Huang, Y.S.; Aalund, G.; Chuang, D.T.; Lau, K.S. Expression and characterization of branched-chain α-ketoacid dehydrogenase kinase from the rat. Is it a histidine-protein kinase? J. Biol.Chem. 1995, 270, 19861–19867
-
(1995)
J. Biol.Chem
, vol.270
, pp. 19861-19867
-
-
Davie, J.R.1
Wynn, R.M.2
Meng, M.3
Huang, Y.S.4
Aalund, G.5
Chuang, D.T.6
Lau, K.S.7
-
126
-
-
0015914742
-
Structural and functional role of leucine residues in proteins
-
Chou, P.Y.; Fasman, G.D. Structural and functional role of leucine residues in proteins. J. Mol. Biol. 1973, 74, 263–281
-
(1973)
J. Mol. Biol
, vol.74
, pp. 263-281
-
-
Chou, P.Y.1
Fasman, G.D.2
-
127
-
-
0028894384
-
Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA
-
Glover, J.N.; Harrison, S.C. Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA. Nature 1995, 373, 257–261
-
(1995)
Nature
, vol.373
, pp. 257-261
-
-
Glover, J.N.1
Harrison, S.C.2
-
128
-
-
0031796861
-
Structure and properties of surfactant protein B
-
Hawgood, S.; Derrick, M.; Poulain, F. Structure and properties of surfactant protein B. Biochim. Biophys. Acta 1998, 1408, 150–160
-
(1998)
Biochim. Biophys. Acta
, vol.1408
, pp. 150-160
-
-
Hawgood, S.1
Derrick, M.2
Poulain, F.3
-
129
-
-
84928225287
-
The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability
-
Chung, J.; Bauer, D.E.; Ghamari, A.; Nizzi, C.P.; Deck, K.M.; Kingsley, P.D.; Yien, Y.Y.; Huston, N.C.; Chen, C.; Schultz, I.J.; et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Sci. Signal.2015, 8, 34
-
(2015)
Sci. Signal
, vol.8
-
-
Chung, J.1
Bauer, D.E.2
Ghamari, A.3
Nizzi, C.P.4
Deck, K.M.5
Kingsley, P.D.6
Yien, Y.Y.7
Huston, N.C.8
Chen, C.9
Schultz, I.J.10
-
130
-
-
34547524771
-
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
-
Meng, F.; Henson, R.; Wehbe-Janek, H.; Ghoshal, K.; Jacob, S.T.; Patel, T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007, 133, 647–658
-
(2007)
Gastroenterology
, vol.133
, pp. 647-658
-
-
Meng, F.1
Henson, R.2
Wehbe-Janek, H.3
Ghoshal, K.4
Jacob, S.T.5
Patel, T.6
-
131
-
-
84862638243
-
Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 incactivation by targeting PTEN
-
Han, M.; Liu, M.; Wang, Y.; Chen, X.; Xu, J.; Sun, Y.; Zhao, L.; Qu, H.; Fan, Y.; Wu, C. Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 incactivation by targeting PTEN. PLoS ONE 2012, 7, e39520
-
(2012)
Plos ONE
, vol.7
-
-
Han, M.1
Liu, M.2
Wang, Y.3
Chen, X.4
Xu, J.5
Sun, Y.6
Zhao, L.7
Qu, H.8
Fan, Y.9
Wu, C.10
-
132
-
-
84864541155
-
TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion
-
Dey, N.; Ghosh-Choudhury, N.; Kasinath, B.S.; Choudhury, G.G. TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion. PLoS ONE 2012, 7, e42316
-
(2012)
Plos ONE
, vol.7
-
-
Dey, N.1
Ghosh-Choudhury, N.2
Kasinath, B.S.3
Choudhury, G.G.4
-
133
-
-
84873621958
-
MiR-21 regulates biological behavior through the PTEN/PI-3K/Akt signaling pathway in human colorectal cancer cells
-
Xiong, B.; Cheng, Y.; Ma, L.; Zhang, C. MiR-21 regulates biological behavior through the PTEN/PI-3K/Akt signaling pathway in human colorectal cancer cells. Int. J. Oncol.2013, 42, 219–228
-
(2013)
Int. J. Oncol
, vol.42
, pp. 219-228
-
-
Xiong, B.1
Cheng, Y.2
Ma, L.3
Zhang, C.4
-
134
-
-
59749091850
-
Complex interplay between Akt, TSC2 and the two mTOR complexes
-
Huang, J.; Manning, B.D. A complex interplay between Akt, TSC2 and the two mTOR complexes. Biochem. Soc. Trans. 2009, 37, 217–222
-
(2009)
Biochem. Soc. Trans
, vol.37
, pp. 217-222
-
-
Huang, J.1
Manning, B.2
-
135
-
-
54249096193
-
MicroRNA-21 targets Sprouty2 and promotes cellular outgrouths
-
Sayed, D.; Rane, S.; Lypowy, J.; He, M.; Chen, I.Y.; Vashistha, H.; Yan, L.; Malhotra, A.; Vatner, D.; Abdellatif, M. MicroRNA-21 targets Sprouty2 and promotes cellular outgrouths. Mol. Biol. Cell 2008, 19, 3272–3282
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 3272-3282
-
-
Sayed, D.1
Rane, S.2
Lypowy, J.3
He, M.4
Chen, I.Y.5
Vashistha, H.6
Yan, L.7
Malhotra, A.8
Vatner, D.9
Abdellatif, M.10
-
136
-
-
80955163793
-
Transcriptional and post-transcriptional regulation of Sprouty1, a receptor tyrosine kinase inhibitor in prostate cancer
-
Dariminpourain, M.; Wang, S.; Ittmann, M.; Kwabi-Addo, B. Transcriptional and post-transcriptional regulation of Sprouty1, a receptor tyrosine kinase inhibitor in prostate cancer. Prostate Cancer Prostatic Dis. 2011, 14, 279–285
-
(2011)
Prostate Cancer Prostatic Dis
, vol.14
, pp. 279-285
-
-
Dariminpourain, M.1
Wang, S.2
Ittmann, M.3
Kwabi-Addo, B.4
-
137
-
-
78751517914
-
Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty
-
Frey, M.R.; Carraro, G.; Batra, R.K.; Polk, D.B.; Warburton, D. Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty. Cancer Biol. Ther. 2011, 11, 122–124
-
(2011)
Cancer Biol. Ther
, vol.11
, pp. 122-124
-
-
Frey, M.R.1
Carraro, G.2
Batra, R.K.3
Polk, D.B.4
Warburton, D.5
-
138
-
-
2942726155
-
The ins and outs of FoxO shuttling: Mechanisms of FoxO translocation and transcriptional regulation
-
Van der Heide, L.P.; Hoekman, M.F.; Smidt, M.P. The ins and outs of FoxO shuttling: Mechanisms of FoxO translocation and transcriptional regulation. Biochem. J. 2004, 380, 297–309
-
(2004)
Biochem. J
, vol.380
, pp. 297-309
-
-
Van Der Heide, L.P.1
Hoekman, M.F.2
Smidt, M.P.3
-
139
-
-
34548289502
-
Dynamic FoxO transcription factors
-
Huang, H.; Tindall, D.J. Dynamic FoxO transcription factors. J. Cell Sci.2007, 120, 2479–2487
-
(2007)
J. Cell Sci
, vol.120
, pp. 2479-2487
-
-
Huang, H.1
Tindall, D.J.2
-
140
-
-
84907189522
-
MiR-21 induces cell proliferation and suppresses the chemosensitivity in glioblastoma cells via downregulation of FOXO1
-
Lei, B.X.; Liu, Z.H.; Li, Z.J.; Li, C.; Deng, Y.F. miR-21 induces cell proliferation and suppresses the chemosensitivity in glioblastoma cells via downregulation of FOXO1. Int. J. Clin. Exp. Med. 2014, 7, 2060–2066
-
(2014)
Int. J. Clin. Exp. Med
, vol.7
, pp. 2060-2066
-
-
Lei, B.X.1
Liu, Z.H.2
Li, Z.J.3
Li, C.4
Deng, Y.F.5
-
141
-
-
84938997840
-
Interplay of miR-21 and FoxO1 modulates growth of pancreatic ductal adenocarcinoma
-
Song, W.; Wang, L.; Wang, L.; Li, Q. Interplay of miR-21 and FoxO1 modulates growth of pancreatic ductal adenocarcinoma. Tumour Biol. 2015, doi:10.1007/s13277-015-3123-x.
-
(2015)
Tumour Biol
-
-
Song, W.1
Wang, L.2
Wang, L.3
Li, Q.4
-
142
-
-
84921350297
-
Modulation of FoxO1 expression by miR-21 to promote growth of pancreatic ductal adenocarcinoma
-
Song, W.; Li, Q.; Wang, L.; Wang, L. Modulation of FoxO1 expression by miR-21 to promote growth of pancreatic ductal adenocarcinoma. Cell. Physiol. Biochem. 2015, 35, 184–190
-
(2015)
Cell. Physiol. Biochem
, vol.35
, pp. 184-190
-
-
Song, W.1
Li, Q.2
Wang, L.3
Wang, L.4
-
143
-
-
84906971939
-
MicroRNA-21 promotes glioblastoma tumorigenesis by down-regulating insulin-like growth factor-binding protein-3 (IGFBP3)
-
Yang, C.H.; Yue, J.; Pfeffer, S.R.; Fan, M.; Paulus, E.; Hosni-Ahmed, A.; Sims, M.; Qayyum, S.; Davidoff, A.M.; Handorf, C.R.; et al. MicroRNA-21 promotes glioblastoma tumorigenesis by down-regulating insulin-like growth factor-binding protein-3 (IGFBP3). J. Biol. Chem.2014, 289, 25079–25087
-
(2014)
J. Biol. Chem
, vol.289
, pp. 25079-25087
-
-
Yang, C.H.1
Yue, J.2
Pfeffer, S.R.3
Fan, M.4
Paulus, E.5
Hosni-Ahmed, A.6
Sims, M.7
Qayyum, S.8
Davidoff, A.M.9
Handorf, C.R.10
-
144
-
-
77951911593
-
FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor
-
Chen, C.C.; Jeon, S.M.; Bhaskar, P.T.; Nogueira, V.; Sundararajan, D.; Tonic, I.; Park, Y.; Hay, N. FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor. Dev. Cell 2010, 18, 592–604
-
(2010)
Dev. Cell
, vol.18
, pp. 592-604
-
-
Chen, C.C.1
Jeon, S.M.2
Bhaskar, P.T.3
Nogueira, V.4
Sundararajan, D.5
Tonic, I.6
Park, Y.7
Hay, N.8
-
145
-
-
80052966977
-
Interplay between FOXO, TOR, and Akt
-
Hay, N. Interplay between FOXO, TOR, and Akt. Biochim. Biophys. Acta 2011, 1813, 1965–1970
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 1965-1970
-
-
Hay, N.1
-
146
-
-
0242539698
-
Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling
-
Jünger, M.A.; Rintelen, F. Stocker, H.; Wasserman, J.D.; Végh, M.; Radimerski, T.; Greenberg, M.E.; Hafen, E. Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J. Biol. 2003, 2, 20
-
(2003)
J. Biol
, vol.2
-
-
Jünger, M.A.1
Rintelen, F.2
Stocker, H.3
Wasserman, J.D.4
Végh, M.5
Radimerski, T.6
Greenberg, M.E.7
Hafen, E.8
-
147
-
-
0042161896
-
Control of cell number by Drosophila FOXO: Downstream and feedback regulation of the insulin receptor pathway
-
Puig, O.; Marr, M.T.; Ruhf, M.L.; Tjian, R. Control of cell number by Drosophila FOXO: Downstream and feedback regulation of the insulin receptor pathway. Genes Dev. 2003, 17, 2006–2020
-
(2003)
Genes Dev
, vol.17
, pp. 2006-2020
-
-
Puig, O.1
Marr, M.T.2
Ruhf, M.L.3
Tjian, R.4
-
148
-
-
84860527756
-
A unifying model for mTORC1-mediated regulation of mRNA translation
-
Thoreen, C.C.; Chantranupong, L.; Keys, H.R.; Wang, T.; Gray, N.S.; Sabatini, D.M. A unifying model for mTORC1-mediated regulation of mRNA translation. Nature 2012, 485, 109–113
-
(2012)
Nature
, vol.485
, pp. 109-113
-
-
Thoreen, C.C.1
Chantranupong, L.2
Keys, H.R.3
Wang, T.4
Gray, N.S.5
Sabatini, D.M.6
-
149
-
-
41749113108
-
MicroRNA-21 (MiR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
-
Asangani, I.A.; Rasheed, S.A.; Nikolova, D.A.; Leupold, J.H.; Colburn, N.H.; Post, S.; Allgayer, H. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008, 27, 2128–2136
-
(2008)
Oncogene
, vol.27
, pp. 2128-2136
-
-
Asangani, I.A.1
Rasheed, S.A.2
Nikolova, D.A.3
Leupold, J.H.4
Colburn, N.H.5
Post, S.6
Allgayer, H.7
-
150
-
-
47549109566
-
MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
-
Lu, Z.; Liu, M.; Stribinskis, V.; Klinge, C.M.; Ramos, K.S.; Colburn, N.H.; Li, Y. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 2008, 27, 4373–4379
-
(2008)
Oncogene
, vol.27
, pp. 4373-4379
-
-
Lu, Z.1
Liu, M.2
Stribinskis, V.3
Klinge, C.M.4
Ramos, K.S.5
Colburn, N.H.6
Li, Y.7
-
151
-
-
43749110929
-
Suppression of programmed cell death 4 (PDCD4) protein expression by BCR-ABL-regulated engagement of the mTOR/p70 S6 kinase pathway
-
Carayol, N.; Katsoulidis, E.; Sassano, A.; Altman, J.K.; Druker, B.J.; Platanias, L.C. Suppression of programmed cell death 4 (PDCD4) protein expression by BCR-ABL-regulated engagement of the mTOR/p70 S6 kinase pathway. J. Biol. Chem. 2008, 28, 8601–8610
-
(2008)
J. Biol. Chem
, vol.28
, pp. 8601-8610
-
-
Carayol, N.1
Katsoulidis, E.2
Sassano, A.3
Altman, J.K.4
Druker, B.J.5
Platanias, L.C.6
-
152
-
-
84871178729
-
Role of p70S6K1-mediated phosphorylation of eIF4B and PDCD4 proteins in the regulation of protein synthesis
-
Dennis, M.D.; Jefferson, L.S.; Kimball, S.R. Role of p70S6K1-mediated phosphorylation of eIF4B and PDCD4 proteins in the regulation of protein synthesis. J. Biol. Chem.2012, 287, 42890–42899
-
(2012)
J. Biol. Chem
, vol.287
, pp. 42890-42899
-
-
Dennis, M.D.1
Jefferson, L.S.2
Kimball, S.R.3
-
153
-
-
46449128469
-
SMAD proteins control DROSHA-mediated microRNA maturation
-
Davis, B.N.; Hilyard, A.C.; Lagna, G.; Hata, A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008, 454, 56–61
-
(2008)
Nature
, vol.454
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
154
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated translational control
-
Ma, X.M.; Blenis, J. Molecular mechanisms of mTOR-mediated translational control. Nat. Rev. Mol. Cell Biol. 2009, 10, 307–318
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
155
-
-
84924365868
-
Computational analysis of an autophagy/translation switch based on mutual inhibition of MTORC1 and ULK1
-
Szymańska, P.; Martin, K.R.; MacKeigan, J.P.; Hlavacek, W.S.; Lipniacki, T. Computational analysis of an autophagy/translation switch based on mutual inhibition of MTORC1 and ULK1. PLoS ONE 2015, 10, e0116550
-
(2015)
Plos ONE
, vol.10
-
-
Szymańska, P.1
Martin, K.R.2
Mackeigan, J.P.3
Hlavacek, W.S.4
Lipniacki, T.5
-
156
-
-
0028786952
-
Repression of cap-dependent translation by 4E-binding protein 1: Competition with p220 for binding to eukaryotic initiation factor-4E
-
Haghighat, A.; Mader, S.; Pause, A.; Sonenberg, N. Repression of cap-dependent translation by 4E-binding protein 1: Competition with p220 for binding to eukaryotic initiation factor-4E. EMBO J. 1995, 14, 5701–5709
-
(1995)
EMBO J
, vol.14
, pp. 5701-5709
-
-
Haghighat, A.1
Mader, S.2
Pause, A.3
Sonenberg, N.4
-
157
-
-
0347281686
-
Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E
-
Gross, J.D.; Moerke, N.J.; von der Haar, T.; Lugovskoy, A.A.; Sachs, A.B.; McCarthy, J.E.; Wagner, G. Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. Cell 2003, 115, 739–750
-
(2003)
Cell
, vol.115
, pp. 739-750
-
-
Gross, J.D.1
Moerke, N.J.2
Von Der Haar, T.3
Lugovskoy, A.A.4
Sachs, A.B.5
McCarthy, J.E.6
Wagner, G.7
-
158
-
-
33846449110
-
Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G
-
Moerke, N.J.; Aktas, H.; Chen, H.; Cantel, S.; Reibarkh, M.Y.; Fahmy, A.; Gross, J.D.; Degterev, A.; Yuan, J.; Chorev, M.; et al. Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G. Cell 2007, 128, 257–267
-
(2007)
Cell
, vol.128
, pp. 257-267
-
-
Moerke, N.J.1
Aktas, H.2
Chen, H.3
Cantel, S.4
Reibarkh, M.Y.5
Fahmy, A.6
Gross, J.D.7
Degterev, A.8
Yuan, J.9
Chorev, M.10
-
159
-
-
47749123500
-
Crystal structure of the yeast eIF4A-eIF4G complex: An RNA-helicase controlled by protein-protein interactions
-
Schütz, P.; Bumann, M.; Oberholzer, A.E.; Bieniossek, C.; Trachsel, H.; Altmann, M.; Baumann, U. Crystal structure of the yeast eIF4A-eIF4G complex: An RNA-helicase controlled by protein-protein interactions. Proc. Natl. Acad. Sci. USA 2008, 105, 9564–9569
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 9564-9569
-
-
Schütz, P.1
Bumann, M.2
Oberholzer, A.E.3
Bieniossek, C.4
Trachsel, H.5
Altmann, M.6
Baumann, U.7
-
160
-
-
62849126891
-
Requirement of RNA binding of mammalian eukaryotic translation initiation factor 4GI (EIF4GI) for efficient interaction of eIF4E with the mRNA cap
-
Yanagiya, A.; Svitkin, Y.V.; Shibata, S.; Mikami, S.; Imataka, H.; Sonenberg, N. Requirement of RNA binding of mammalian eukaryotic translation initiation factor 4GI (eIF4GI) for efficient interaction of eIF4E with the mRNA cap. Mol. Cell. Biol. 2009, 29, 1661–1669
-
(2009)
Mol. Cell. Biol
, vol.29
, pp. 1661-1669
-
-
Yanagiya, A.1
Svitkin, Y.V.2
Shibata, S.3
Mikami, S.4
Imataka, H.5
Sonenberg, N.6
-
161
-
-
59049092956
-
Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation
-
Marintchev, A.; Edmonds, K.A.; Marintcheva, B.; Hendrickson, E.; Oberer, M.; Suzuki, C.; Herdy, B.; Sonenberg, N.; Wagner, G. Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation. Cell 2009, 136, 447–460
-
(2009)
Cell
, vol.136
, pp. 447-460
-
-
Marintchev, A.1
Edmonds, K.A.2
Marintcheva, B.3
Hendrickson, E.4
Oberer, M.5
Suzuki, C.6
Herdy, B.7
Sonenberg, N.8
Wagner, G.9
-
162
-
-
2442574729
-
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases
-
Raught, B.; Peiretti F.; Gingras, A.C.; Livingstone, M.; Shahbazian, D.; Mayeur, G.L.; Polakiewicz, R.D.; Sonenberg, N.; Hershey, J.W. Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases. EMBO J. 2004, 23, 1761–1769
-
(2004)
EMBO J
, vol.23
, pp. 1761-1769
-
-
Raught, B.1
Peiretti, F.2
Gingras, A.C.3
Livingstone, M.4
Shahbazian, D.5
Mayeur, G.L.6
Polakiewicz, R.D.7
Sonenberg, N.8
Hershey, J.W.9
-
163
-
-
27744569843
-
MTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
-
Holz, M.K.; Ballif, B.A.; Gygi, S.P.; Blenis, J. mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell 2005, 123, 569–580
-
(2005)
Cell
, vol.123
, pp. 569-580
-
-
Holz, M.K.1
Ballif, B.A.2
Gygi, S.P.3
Blenis, J.4
-
164
-
-
42149192536
-
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains
-
Suzuki, C.; Garces, R.G.; Edmonds, K.A.; Hiller, S.; Hyberts, S.G.; Marintchev, A.; Wagner, G. PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains. Proc. Natl. Acad. Sci. USA 2008, 105, 3274–3279
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3274-3279
-
-
Suzuki, C.1
Garces, R.G.2
Edmonds, K.A.3
Hiller, S.4
Hyberts, S.G.5
Marintchev, A.6
Wagner, G.7
-
165
-
-
62549164363
-
Crystal structure of the eIF4A-PDCD4 complex
-
Chang, J.H.; Cho, Y.H.; Sohn, S.Y.; Choi, J.M.; Kim, A.; Kim, Y.C.; Jang, S.K.; Cho, Y. Crystal structure of the eIF4A-PDCD4 complex. Proc. Natl. Acad. Sci. USA 2009, 106, 3148–3153
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 3148-3153
-
-
Chang, J.H.1
Cho, Y.H.2
Sohn, S.Y.3
Choi, J.M.4
Kim, A.5
Kim, Y.C.6
Jang, S.K.7
Cho, Y.8
-
166
-
-
84917708600
-
Crosstalk between Edc4 and mammalian target of rapamycin complex 1 (MTORC1) signaling in mRNA decapping
-
Rahman, H.; Qasim, M.; Oellerich, M.; Asif, A.R. Crosstalk between Edc4 and mammalian target of rapamycin complex 1 (mTORC1) signaling in mRNA decapping. Int. J. Mol. Sci. 2014, 15, 23179–23195
-
(2014)
Int. J. Mol. Sci
, vol.15
, pp. 23179-23195
-
-
Rahman, H.1
Qasim, M.2
Oellerich, M.3
Asif, A.R.4
-
167
-
-
28344456221
-
Ge-1 is a central component of the mammalian cytoplasmic mRNA processing body
-
Yu, J.H.; Yang, W.H.; Gulick, T.; Bloch, K.D.; Bloch, D.B. Ge-1 is a central component of the mammalian cytoplasmic mRNA processing body. RNA 2005, 11, 1795–1802
-
(2005)
RNA
, vol.11
, pp. 1795-1802
-
-
Yu, J.H.1
Yang, W.H.2
Gulick, T.3
Bloch, K.D.4
Bloch, D.B.5
-
168
-
-
45849122499
-
Widespread translational inhibition by plant miRNAs and siRNAs
-
Brodersen, P.; Sakvarelidze-Achard, L.; Bruun-Rasmussen, M.; Dunoyer, P.; Yamamoto, Y.Y.; Sieburth, L.; Voinnet, O. Widespread translational inhibition by plant miRNAs and siRNAs. Science 2008, 320, 1185–1190
-
(2008)
Science
, vol.320
, pp. 1185-1190
-
-
Brodersen, P.1
Sakvarelidze-Achard, L.2
Bruun-Rasmussen, M.3
Dunoyer, P.4
Yamamoto, Y.Y.5
Sieburth, L.6
Voinnet, O.7
-
169
-
-
84876865975
-
The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans
-
Bossé, G.D.; Rüegger, S.; Ow, M.C.; Vasquez-Rifo, A.; Rondeau, E.L.; Ambros, V.R.; Grosshans, H.; Simard, M.J. The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans. Mol. Cell 2013, 50, 28128–28127
-
(2013)
Mol. Cell
, vol.50
, pp. 28127-28128
-
-
Bossé, G.D.1
Rüegger, S.2
Ow, M.C.3
Vasquez-Rifo, A.4
Rondeau, E.L.5
Ambros, V.R.6
Grosshans, H.7
Simard, M.J.8
-
170
-
-
84925491509
-
MTORC1-mediated translational elongation limits intestinal tumour initiation and growth
-
Faller, W.J.; Jackson, T.J.; Knight, J.R.; Ridgway, R.A.; Jamieson, T.; Karim, S.A.; Jones, C.; Radulescu, S.; Huels, D.J.; Myant, K.B.; et al. mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature 2015, 517, 497–500
-
(2015)
Nature
, vol.517
, pp. 497-500
-
-
Faller, W.J.1
Jackson, T.J.2
Knight, J.R.3
Ridgway, R.A.4
Jamieson, T.5
Karim, S.A.6
Jones, C.7
Radulescu, S.8
Huels, D.J.9
Myant, K.B.10
-
171
-
-
84877720366
-
The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4
-
Csibi, A.; Fendt, S.M.; Li, C.; Poulogiannis, G.; Choo, A.Y.; Chapski, D.J.; Jeong, S.M.; Dempsey, J.M.; Parkhitko, A.; Morrison, T.; et al. The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4. Cell 2013, 153, 840–854
-
(2013)
Cell
, vol.153
, pp. 840-854
-
-
Csibi, A.1
Fendt, S.M.2
Li, C.3
Poulogiannis, G.4
Choo, A.Y.5
Chapski, D.J.6
Jeong, S.M.7
Dempsey, J.M.8
Parkhitko, A.9
Morrison, T.10
-
172
-
-
84897977386
-
Environmental signaling through the mechanistic target of rapamycin complex 1: MTORC1 goes nuclear
-
Workman, J.J.; Chen, H.; Laribee, R.N. Environmental signaling through the mechanistic target of rapamycin complex 1: mTORC1 goes nuclear. Cell Cycle 2014, 13, 714–725
-
(2014)
Cell Cycle
, vol.13
, pp. 714-725
-
-
Workman, J.J.1
Chen, H.2
Laribee, R.N.3
-
173
-
-
41949107421
-
Cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner
-
Smith, E.M.; Proud, C.G. Cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner. EMBO J. 2008, 27, 1005–1016
-
(2008)
EMBO J
, vol.27
, pp. 1005-1016
-
-
Smith, E.M.1
Proud, C.G.2
-
174
-
-
0035225871
-
Regulation of translation initiation by amino acids in eukaryotic cells
-
Kimball, S.R. Regulation of translation initiation by amino acids in eukaryotic cells. Prog. Mol. Subcell. Biol. 2001, 26, 155–184
-
(2001)
Prog. Mol. Subcell
, vol.26
, pp. 155-184
-
-
Kimball, S.R.1
-
175
-
-
0036440779
-
Regulation of mammalian translation factors by nutrients
-
Proud, C.G. Regulation of mammalian translation factors by nutrients. Eur. J. Biochem. 2002, 269, 5338–5349
-
(2002)
Eur. J. Biochem
, vol.269
, pp. 5338-5349
-
-
Proud, C.G.1
-
176
-
-
84876782429
-
Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism
-
Schriever, S.C.; Deutsch, M.J.; Adamski, J.; Roscher, A.A.; Ensenauer, R. Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism. J. Nutr. Biochem.2013, 24, 824–831
-
(2013)
J. Nutr. Biochem
, vol.24
, pp. 824-831
-
-
Schriever, S.C.1
Deutsch, M.J.2
Adamski, J.3
Roscher, A.A.4
Ensenauer, R.5
-
177
-
-
84891438317
-
Control of the translational machinery by amino acids
-
Proud, C.G. Control of the translational machinery by amino acids. Am. J. Clin. Nutr. 2014, 99, 231S–236S.
-
(2014)
Am. J. Clin. Nutr
, vol.99
-
-
Proud, C.G.1
-
178
-
-
84862758071
-
Smad-mediated regulation of microRNA biosynthesis
-
Blahna, M.T.; Hata, A. Smad-mediated regulation of microRNA biosynthesis. FEBS Lett. 2012, 586, 1906–1912
-
(2012)
FEBS Lett
, vol.586
, pp. 1906-1912
-
-
Blahna, M.T.1
Hata, A.2
-
179
-
-
34250770436
-
Transforming growth factor-β and microRNA:MRNA regulatory networks in epithelial plasticity
-
Zavadil, J.; Narasimhan, M.; Blumenberg, M.; Schneider, R.J. Transforming growth factor-β and microRNA:mRNA regulatory networks in epithelial plasticity. Cells Tissues Organs 2007, 185, 157–161
-
(2007)
Cells Tissues Organs
, vol.185
, pp. 157-161
-
-
Zavadil, J.1
Narasimhan, M.2
Blumenberg, M.3
Schneider, R.J.4
-
180
-
-
84908610762
-
Jones, S.N.; et al. Reassessment of the role of TSC, mTORC1 and microRNAs in amino acids mediated translational control of TOP mRNAs
-
Patursky-Polischuk, I.; Kasir, J.; Miloslavski, R.; Hayouka, Z.; Hausner-Hanochi, M.; Stolovich-Rain, M.; Tsukerman, P.; Biton, M.; Mudhasani, R.; Jones, S.N.; et al. Reassessment of the role of TSC, mTORC1 and microRNAs in amino acids mediated translational control of TOP mRNAs. PLoS ONE 2014, 9, e109410
-
(2014)
Plos ONE
, vol.9
-
-
Patursky-Polischuk, I.1
Kasir, J.2
Miloslavski, R.3
Hayouka, Z.4
Hausner-Hanochi, M.5
Stolovich-Rain, M.6
Tsukerman, P.7
Biton, M.8
Mudhasani, R.9
-
181
-
-
37549032568
-
Raptor-rictor axis in TGFβ-induced protein synthesis
-
Das, F.; Ghosh-Choudhury, N.; Mahimainathan, L.; Venkatesan, B.; Feliers, D.; Riley, D.J.; Kasinath, B.S.; Choudhury, G.G. Raptor-rictor axis in TGFβ-induced protein synthesis. Cell Signal. 2008, 20, 409–423
-
(2008)
Cell Signal
, vol.20
, pp. 409-423
-
-
Das, F.1
Ghosh-Choudhury, N.2
Mahimainathan, L.3
Venkatesan, B.4
Feliers, D.5
Riley, D.J.6
Kasinath, B.S.7
Choudhury, G.G.8
-
182
-
-
84908110053
-
TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression
-
Das, F.; Bera, A.; Ghosh-Choudhury, N.; Abboud, H.E.; Kasinath, B.S.; Choudhury, G.G. TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression. PLoS ONE 2014, 9, e109608
-
(2014)
Plos ONE
, vol.9
-
-
Das, F.1
Bera, A.2
Ghosh-Choudhury, N.3
Abboud, H.E.4
Kasinath, B.S.5
Choudhury, G.G.6
-
183
-
-
84875135419
-
Integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy
-
Das, F.; Ghosh-Choudhury, N.; Bera, A.; Dey, N.; Abboud, H.E.; Kasinath, B.S.; Choudhury, G.G. Transforming growth factor β integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy. J. Biol. Chem. 2013, 288, 7756–7768
-
(2013)
J. Biol. Chem
, vol.288
, pp. 7756-7768
-
-
Das, F.1
Ghosh-Choudhury, N.2
Bera, A.3
Dey, N.4
Abboud, H.E.5
Kasinath, B.S.6
Choudhury, G.G.7
-
184
-
-
35148819133
-
NUTRIX Consortium. Milk consumption during pregnancy is associated with increased infant size at birth: Prospective cohort study
-
Olsen, S.F.; Halldorsson, T.I.; Willett, W.C.; Knudsen, V.K.; Gillman, M.W.; Mikkelsen, T.B.; Olsen, J.; NUTRIX Consortium. Milk consumption during pregnancy is associated with increased infant size at birth: Prospective cohort study. Am. J. Clin. Nutr. 2007, 86, 1104–1110
-
(2007)
Am. J. Clin. Nutr
, vol.86
, pp. 1104-1110
-
-
Olsen, S.F.1
Halldorsson, T.I.2
Willett, W.C.3
Knudsen, V.K.4
Gillman, M.W.5
Mikkelsen, T.B.6
Olsen, J.7
-
185
-
-
79960857743
-
Maternal milk consumption, fetal growth, and the risks of neonatal complications: The Generation R Study
-
Heppe, D.H.; van Dam, R.M.; Willemsen, S.P.; den Breeijen, H.; Raat, H.; Hofman, A.; Steegers, E.A.; Jaddoe, V.W. Maternal milk consumption, fetal growth, and the risks of neonatal complications: The Generation R Study. Am. J. Clin. Nutr. 2011, 94, 501–509
-
(2011)
Am. J. Clin. Nutr
, vol.94
, pp. 501-509
-
-
Heppe, D.H.1
Van Dam, R.M.2
Willemsen, S.P.3
Den Breeijen, H.4
Raat, H.5
Hofman, A.6
Steegers, E.A.7
Jaddoe, V.W.8
-
186
-
-
84926340588
-
Milk consumption during pregnancy increases birth weight, a risk factor for the development of diseases of civilization
-
Melnik, B.C.; John, S.M.; Schmitz, G. Milk consumption during pregnancy increases birth weight, a risk factor for the development of diseases of civilization. J. Transl. Med. 2015, 13, doi:10.1186/s12967-014-0377-9
-
(2015)
J. Transl. Med
, pp. 13
-
-
Melnik, B.C.1
John, S.M.2
Schmitz, G.3
-
187
-
-
34347211057
-
Jansson, T. Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted growth
-
Roos, S.; Jansson, N.; Palmberg, I.; Säljö, K.; Powell, T.L.; Jansson, T. Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted growth. J. Physiol. 2007, 582, 449–459
-
(2007)
J. Physiol
, vol.582
, pp. 449-459
-
-
Roos, S.1
Jansson, N.2
Palmberg, I.3
Säljö, K.4
Powell, T.L.5
-
188
-
-
84869094274
-
The emerging role of mTORC1 signaling in placental nutrient-sensing
-
Jansson, T.; Aye, I.L.; Goberdhan, D.C. The emerging role of mTORC1 signaling in placental nutrient-sensing. Placenta 2012, 33, e23–e29
-
(2012)
Placenta
, vol.33
-
-
Jansson, T.1
Aye, I.L.2
Goberdhan, D.C.3
-
189
-
-
70349246381
-
Regulation of amino acid transporters by glucose and growth factors in cultured primary human trophoblast cells is mediated by mTOR signaling
-
Roos, S.; Lagerlöf, O.; Wennergren, M.; Powell, T.L.; Jansson, T. Regulation of amino acid transporters by glucose and growth factors in cultured primary human trophoblast cells is mediated by mTOR signaling. Am. J. Physiol. Cell Physiol. 2009, 297, C723–C731
-
(2009)
Am. J. Physiol. Cell Physiol
, vol.297
-
-
Roos, S.1
Lagerlöf, O.2
Wennergren, M.3
Powell, T.L.4
Jansson, T.5
-
190
-
-
84872068779
-
Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies
-
Jansson, N.; Rosario, F.J.; Gaccioli, F.; Lager, S.; Jones, H.N.; Roos, S.; Jansson, T.; Powell, T.L. Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies. J. Clin. Endocrinol. Metab. 2013, 98, 105–113
-
(2013)
J. Clin. Endocrinol. Metab
, vol.98
, pp. 105-113
-
-
Jansson, N.1
Rosario, F.J.2
Gaccioli, F.3
Lager, S.4
Jones, H.N.5
Roos, S.6
Jansson, T.7
Powell, T.L.8
-
191
-
-
84920950261
-
Aberrant upregulation of miR-21 in placental tissues of macrosomia
-
Jiang, H.; Wu, W.; Zhang, M.; Li, J.; Peng, Y.; Miao, T.T.; Zhu, H.; Xu, G. Aberrant upregulation of miR-21 in placental tissues of macrosomia. J. Perinatol. 2014, 34, 658–663
-
(2014)
J. Perinatol
, vol.34
, pp. 658-663
-
-
Jiang, H.1
Wu, W.2
Zhang, M.3
Li, J.4
Peng, Y.5
Miao, T.T.6
Zhu, H.7
Xu, G.8
-
192
-
-
84899786094
-
Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2α signaling and increases fetal growth in rats
-
Gaccioli, F.; White, V.; Capobianco, E.; Powell, T.L.; Jawerbaum, A.; Jansson, T. Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2α signaling and increases fetal growth in rats. Biol. Reprod. 2013, 89, doi:10.1095/biolreprod.113.109702
-
(2013)
Biol. Reprod
-
-
Gaccioli, F.1
White, V.2
Capobianco, E.3
Powell, T.L.4
Jawerbaum, A.5
Jansson, T.6
-
193
-
-
84892438859
-
Fisetin regulates obesity by targeting mTORC1 signaling
-
Jung, C.H.; Kim, H.; Ahn, J.; Jeon, T.I.; Lee, D.H.; Ha, T.Y. Fisetin regulates obesity by targeting mTORC1 signaling. J. Nutr. Biochem.2013, 24, 1547–1554
-
(2013)
J. Nutr. Biochem
, vol.24
, pp. 1547-1554
-
-
Jung, C.H.1
Kim, H.2
Ahn, J.3
Jeon, T.I.4
Lee, D.H.5
Ha, T.Y.6
-
194
-
-
77953555973
-
Dairy and milk consumption and child growth: Is BMI involved? An analysis of NHANES 1999–2004
-
Wiley, A.S. Dairy and milk consumption and child growth: Is BMI involved? An analysis of NHANES 1999–2004. Am. J. Hum. Biol.2010, 22, 517–525
-
(2010)
Am. J. Hum. Biol
, vol.22
, pp. 517-525
-
-
Wiley, A.S.1
-
195
-
-
20644451593
-
Milk, dairy fat, dietary calcium, and weight gain
-
Berkey, C.S.; Rocket, H.R.; Willet, W.C.; Colditz, G.A. Milk, dairy fat, dietary calcium, and weight gain. Arch. Pediatr. Adolesc. Med. 2005, 159, 543–550
-
(2005)
Arch. Pediatr. Adolesc. Med
, vol.159
, pp. 543-550
-
-
Berkey, C.S.1
Rocket, H.R.2
Willet, W.C.3
Colditz, G.A.4
-
196
-
-
79959465223
-
The risk of child and adolescent overweight is related to types of food consumed
-
Matthews, V.L.; Wien, M.; Sabaté, J. The risk of child and adolescent overweight is related to types of food consumed. Nutr. J. 2011, 10, 71–74
-
(2011)
Nutr. J
, vol.10
, pp. 71-74
-
-
Matthews, V.L.1
Wien, M.2
Sabaté, J.3
-
197
-
-
84872162703
-
Skim milk, whey, and casein increase body weight and whey and casein increase plasma C-peptide concentration in overweight adolescents
-
Arnberg, K.; Mølgaard, C.; Michaelsen, K.F.; Jensen, S.M.; Trolle, E.; Larnkjær, A. Skim milk, whey, and casein increase body weight and whey and casein increase plasma C-peptide concentration in overweight adolescents. J. Nutr. 2012, 142, 2083–2090
-
(2012)
J. Nutr
, vol.142
, pp. 2083-2090
-
-
Arnberg, K.1
Mølgaard, C.2
Michaelsen, K.F.3
Jensen, S.M.4
Trolle, E.5
Larnkjær, A.6
-
198
-
-
0034222276
-
Effects of increased consumption of fluid milk on energy and nutrient intake, body weight, and cardiovascular risk factors in healthy older adults
-
Barr, S.I.; McCarron, D.A.; Heaney, R.P.; Dawson-Hughes, B.; Berga, S.L.; Stern, J.S.; Oparil, S. Effects of increased consumption of fluid milk on energy and nutrient intake, body weight, and cardiovascular risk factors in healthy older adults. Am. J. Diet. Assoc. 2000, 100, 810–817
-
(2000)
Am. J. Diet. Assoc
, vol.100
, pp. 810-817
-
-
Barr, S.I.1
McCarron, D.A.2
Heaney, R.P.3
Dawson-Hughes, B.4
Berga, S.L.5
Stern, J.S.6
Oparil, S.7
-
199
-
-
84885401110
-
Effects of high and low fat dairy food on cardio-metabolic risk factors: A meta-analysis of randomized studies
-
Benatar, J.R.; Sidhu, K.; Stewart, R.A. Effects of high and low fat dairy food on cardio-metabolic risk factors: A meta-analysis of randomized studies. PLoS ONE 2013, 8, e76480
-
(2013)
Plos ONE
, vol.8
-
-
Benatar, J.R.1
Sidhu, K.2
Stewart, R.A.3
-
200
-
-
76149089109
-
Relationship between infant weight gain and later asthma
-
Paul, I.M.; Camera, L.; Zeiger, R.S.; Guilbert, T.W.; Bacharier, L.B.; Taussig, L.M.; Morgan, W.J.; Covar, R.A.; Krawiec, M.; Bloomberg, G.R.; et al. Relationship between infant weight gain and later asthma. Pediatr. Allergy Immunol. 2010, 21, 82–89
-
(2010)
Pediatr. Allergy Immunol
, vol.21
, pp. 82-89
-
-
Paul, I.M.1
Camera, L.2
Zeiger, R.S.3
Guilbert, T.W.4
Bacharier, L.B.5
Taussig, L.M.6
Morgan, W.J.7
Covar, R.A.8
Krawiec, M.9
Bloomberg, G.R.10
-
201
-
-
34548487258
-
The link between the epidemics of obesity and allergic diseases: Does obesity induce decreased immune tolerance?
-
Hersoug, L.G.; Linneberg, A. The link between the epidemics of obesity and allergic diseases: Does obesity induce decreased immune tolerance? Allergy 2007, 62, 1205–1213
-
(2007)
Allergy
, vol.62
, pp. 1205-1213
-
-
Hersoug, L.G.1
Linneberg, A.2
-
202
-
-
58849112157
-
Obesity and allergic diseases
-
Gorgievska-Sukaroovska, B.; Lipozencić, J.; Susac, A. Obesity and allergic diseases. Acta Dermatovenerol. Croat. 2008, 16, 231–235
-
(2008)
Acta Dermatovenerol. Croat
, vol.16
, pp. 231-235
-
-
Gorgievska-Sukaroovska, B.1
Lipozencić, J.2
Susac, A.3
-
203
-
-
18144391936
-
The epidemiology of obesity and asthma
-
Ford, E.S. The epidemiology of obesity and asthma. J. Allergy Clin. Immunol. 2005, 115, 897–909
-
(2005)
J. Allergy Clin. Immunol
, vol.115
, pp. 897-909
-
-
Ford, E.S.1
-
204
-
-
66849138606
-
Lower protein in infant formula is associated with lower weight up tp age 2 year: A randomized clinical trial
-
Koletzko, B.; von Kries, R.; Closa, R.; Escribano, J.; Scaglioni, S.; Giovannini, M.; Beyer, J.; Demmelmair, H.; Gruszfeld, D.; Dobrzanska, A.; et al. Lower protein in infant formula is associated with lower weight up tp age 2 year: A randomized clinical trial. Am. J. Clin. Nutr. 2009, 89, 1836–1845
-
(2009)
Am. J. Clin. Nutr
, vol.89
, pp. 1836-1845
-
-
Koletzko, B.1
Von Kries, R.2
Closa, R.3
Escribano, J.4
Scaglioni, S.5
Giovannini, M.6
Beyer, J.7
Demmelmair, H.8
Gruszfeld, D.9
Dobrzanska, A.10
-
205
-
-
84859631534
-
Effect of protein intake and weight gain velocity on body fat mass at 6 months of age: The EU Childhood Obesity Programme
-
Escribano, J.; Luque, V.; Ferre, N.; Mendez-Riera, G.; Koletzko, B.; Grote, V.; Demmelmair, H.; Bluck, L.; Wright, A.; Closa-Monasterolo, R.; et al. Effect of protein intake and weight gain velocity on body fat mass at 6 months of age: The EU Childhood Obesity Programme. Int. J. Obes.2012, 36, 548–553
-
(2012)
Int. J. Obes
, vol.36
, pp. 548-553
-
-
Escribano, J.1
Luque, V.2
Ferre, N.3
Mendez-Riera, G.4
Koletzko, B.5
Grote, V.6
Demmelmair, H.7
Bluck, L.8
Wright, A.9
Closa-Monasterolo, R.10
-
206
-
-
84898987245
-
Lower protein content in infant formula reduces BMI and obesity risk at school age: Follow-up of a randomized trial
-
Weber, M.; Grote, V.; Closa-Monasterolo, R.; Escribano, J.; Langhendries, J.P.; Dain, E.; Giovannini, M.; Verduci, E.; Gruszfeld, D.; Socha, P.; et al. Lower protein content in infant formula reduces BMI and obesity risk at school age: Follow-up of a randomized trial. Am. J. Clin. Nutr. 2014, 99, 1–11
-
(2014)
Am. J. Clin. Nutr
, vol.99
, pp. 1-11
-
-
Weber, M.1
Grote, V.2
Closa-Monasterolo, R.3
Escribano, J.4
Langhendries, J.P.5
Dain, E.6
Giovannini, M.7
Verduci, E.8
Gruszfeld, D.9
Socha, P.10
-
207
-
-
84866159758
-
Excessive leucine-mTORC1-signalling of cow milk-based infant formula: The missing link to understand early childhood obesity
-
Melnik, B.C. Excessive leucine-mTORC1-signalling of cow milk-based infant formula: The missing link to understand early childhood obesity. J. Obes. 2012, 2012, doi:10.1155/2012/197653
-
(2012)
J. Obes
, vol.2012
-
-
Melnik, B.C.1
-
208
-
-
84896724426
-
Body mass index and the incidence of asthma in children
-
Brüske, I.; Flexeder, C.; Heinrich, J. Body mass index and the incidence of asthma in children. Curr. Opin. Allergy Clin. Immunol. 2014, 14, 155–160
-
(2014)
Curr. Opin. Allergy Clin. Immunol
, vol.14
, pp. 155-160
-
-
Brüske, I.1
Flexeder, C.2
Heinrich, J.3
-
209
-
-
84900814107
-
Subsets of regulatory T cells and their roles in allergy
-
Zhang, H.; Kong, H.; Zeng, X.; Guo, L.; Sun, X.; He, S. Subsets of regulatory T cells and their roles in allergy. J. Transl. Med. 2014, 12, doi:10.1186/1479-5876-12-125
-
(2014)
J. Transl. Med
, vol.12
-
-
Zhang, H.1
Kong, H.2
Zeng, X.3
Guo, L.4
Sun, X.5
He, S.6
-
210
-
-
77957054466
-
The mammalian target of rapamycin: Linking T cell differentiation, function, and metabolism
-
Powell, J.D.; Delgoffe, G.M. The mammalian target of rapamycin: Linking T cell differentiation, function, and metabolism. Immunity 2010, 33, 301–311
-
(2010)
Immunity
, vol.33
, pp. 301-311
-
-
Powell, J.D.1
Delgoffe, G.M.2
-
211
-
-
66949173728
-
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment
-
Delgoffe, G.M.; Kole, T.P.; Zheng, Y.; Zarek, P.E.; Matthews, K.L.; Xiao, B.; Worley, P.F.; Kozma, S.C.; Powell, J.D. The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity 2009, 30, 832–844
-
(2009)
Immunity
, vol.30
, pp. 832-844
-
-
Delgoffe, G.M.1
Kole, T.P.2
Zheng, Y.3
Zarek, P.E.4
Matthews, K.L.5
Xiao, B.6
Worley, P.F.7
Kozma, S.C.8
Powell, J.D.9
-
212
-
-
67749091321
-
Infectious tolerance via the consumption of essential amino acids and mTOR signaling
-
Cobbold, S.P.; Adams, E.; Farquhar, C.A.; Nolan, K.F.; Howie, D.; Lui, K.O.; Fairchild, P.J.; Mellor, A.L.; Ron, D.; Waldmann, H. Infectious tolerance via the consumption of essential amino acids and mTOR signaling. Proc. Natl. Acad. Sci. USA 2009, 106, 12055–12060
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12055-12060
-
-
Cobbold, S.P.1
Adams, E.2
Farquhar, C.A.3
Nolan, K.F.4
Howie, D.5
Lui, K.O.6
Fairchild, P.J.7
Mellor, A.L.8
Ron, D.9
Waldmann, H.10
-
213
-
-
41149113441
-
The AKT-mTOR axis regulates de novo differentiation of CD4+FoxP3+ cells
-
Haxhinasto, S.; Mathis, D.; Benoist, C. The AKT-mTOR axis regulates de novo differentiation of CD4+FoxP3+ cells. J. Exp. Med. 2008, 205, 565–574
-
(2008)
J. Exp. Med
, vol.205
, pp. 565-574
-
-
Haxhinasto, S.1
Mathis, D.2
Benoist, C.3
-
214
-
-
45549098562
-
T cell receptor signaling controls FoxP3 expression via PI3K, Akt, and mTOR
-
Sauer, S.; Bruno, L.; Hertweck, A.; Finlay, D.; Leleu, M.; Spivakov, M.; Knight, Z.A.; Cobb, B.S.; Cantrell, D.; O’Connor, E.; et al. T cell receptor signaling controls FoxP3 expression via PI3K, Akt, and mTOR. Proc. Natl. Acad. Sci. USA 2008, 105, 7797–7802
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 7797-7802
-
-
Sauer, S.1
Bruno, L.2
Hertweck, A.3
Finlay, D.4
Leleu, M.5
Spivakov, M.6
Knight, Z.A.7
Cobb, B.S.8
Cantrell, D.9
O’Connor, E.10
-
215
-
-
84859416933
-
Cells: Mechanisms of differentiation and function
-
Josefowicz, S.Z.; Lu, L.F.; Rudensky, A.Y. Regulatory T cells: Mechanisms of differentiation and function. Annu. Rev. Immunol. 2012, 30, 531–564
-
(2012)
Annu. Rev. Immunol
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
Lu, L.F.2
Rudensky, A.Y.3
Regulatory, T.4
-
216
-
-
65649132344
-
Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps
-
Xu, G.; Xia, J.; Hua, X.; Zhou, H.; Yu, C.; Liu, Z.; Cai, K.; Shi, J.; Li, H. Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps. Respir. Res. 2009, 10, doi:10.1186/1465-9921-10-13
-
(2009)
Respir. Res
-
-
Xu, G.1
Xia, J.2
Hua, X.3
Zhou, H.4
Yu, C.5
Liu, Z.6
Cai, K.7
Shi, J.8
Li, H.9
-
217
-
-
84904527116
-
The potential mechanistic link between allergy and obesity development and infant formula feeding
-
Melnik, B.C. The potential mechanistic link between allergy and obesity development and infant formula feeding. Allergy Asthma Clin. Immunol. 2014, 10, doi:10.1186/1710-1492-10-37
-
(2014)
Allergy Asthma Clin. Immunol
-
-
Melnik, B.C.1
-
218
-
-
85050578655
-
Serum microRNA-21 as a biomarker for allergic inflammatory disease in children
-
in press
-
Sawant, D.V.; Yao, W.; Wright, Z.; Sawyers, C.; Tepper, R.S.; Gupta, S.K.; Kaplan, M.H.; Dent, A.L. Serum microRNA-21 as a biomarker for allergic inflammatory disease in children. Microrna2015, in press.
-
(2015)
Microrna
-
-
Sawant, D.V.1
Yao, W.2
Wright, Z.3
Sawyers, C.4
Tepper, R.S.5
Gupta, S.K.6
Kaplan, M.H.7
Dent, A.L.8
-
219
-
-
79952096291
-
Evidence for acne-promoting effects of milk and other insulinotropic dairy products
-
Melnik, B.C. Evidence for acne-promoting effects of milk and other insulinotropic dairy products. Nestle Nutr. Workshop Ser. Pediatr. Program 2011, 67, 131–145
-
(2011)
Nestle Nutr. Workshop Ser. Pediatr. Program
, vol.67
, pp. 131-145
-
-
Melnik, B.C.1
-
220
-
-
84938056795
-
Linking diet to acne metabolomics, inflammation, and comedogenesis: An update
-
Melnik, B.C. Linking diet to acne metabolomics, inflammation, and comedogenesis: An update. Clin. Cosmet. Investig. Dermatol. 2015, 8, 371–388
-
(2015)
Clin. Cosmet. Investig. Dermatol
, vol.8
, pp. 371-388
-
-
Melnik, B.C.1
-
221
-
-
84886410712
-
Acne: Risk indicator for increased body mass index and insulin resistance
-
Melnik, B.C.; John, S.M.; Plewig G. Acne: Risk indicator for increased body mass index and insulin resistance. Acta Derm. Venereol. 2013, 93, 644–649
-
(2013)
Acta Derm. Venereol
, vol.93
, pp. 644-649
-
-
Melnik, B.C.1
John, S.M.2
Plewig, G.3
-
222
-
-
84887842393
-
The role of mTORC1 in acne pathogenesis and treatment
-
Melnik, B.C. The role of mTORC1 in acne pathogenesis and treatment. Exp. Rev. Dermatol. 2013, 8, 617–622
-
(2013)
Exp. Rev. Dermatol
, vol.8
, pp. 617-622
-
-
Melnik, B.C.1
-
223
-
-
84869146585
-
Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults
-
Di Landro, A.; Cazzaniga, S.; Parazzini, F.; Ingordo, V.; Cusano, F.; Atzori, L.; Cutrì, F.T.; Musumeci, M.L.; Zinetti, C.; Pezzarossa, E.; et al. Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults. J. Am. Acad. Dermatol. 2012, 67, 1129–1135
-
(2012)
J. Am. Acad. Dermatol
, vol.67
, pp. 1129-1135
-
-
Di Landro, A.1
Cazzaniga, S.2
Parazzini, F.3
Ingordo, V.4
Cusano, F.5
Atzori, L.6
Cutrì, F.T.7
Musumeci, M.L.8
Zinetti, C.9
Pezzarossa, E.10
-
224
-
-
84955177195
-
Musumeci, M.L.; et al. The constellation of dietary factors in adolescent acne: A semantic connectivity map approach
-
Grossi, E.; Cazzaniga, S.; Crotti, S.; Naldi, L.; di Landro, A.; Ingordo, V.; Cusano, F.; Atzori, L.; Tripodi Cutrì, F.; Musumeci, M.L.; et al. The constellation of dietary factors in adolescent acne: A semantic connectivity map approach. J. Eur. Acad. Dermatol. Venereol. 2014, doi:10.1111/jdv.12878
-
(2014)
J. Eur. Acad. Dermatol. Venereol
-
-
Grossi, E.1
Cazzaniga, S.2
Crotti, S.3
Naldi, L.4
Di Landro, A.5
Ingordo, V.6
Cusano, F.7
Atzori, L.8
Tripodi Cutrì, F.9
-
225
-
-
84894048655
-
Relationships of self-reported dietary factors and perceived acne severity in a cohort of New York young adults
-
Burris, J.; Rietkerk, W.; Woolf, K. Relationships of self-reported dietary factors and perceived acne severity in a cohort of New York young adults. J. Acad. Nutr. Diet. 2014, 114, 384–392
-
(2014)
J. Acad. Nutr. Diet
, vol.114
, pp. 384-392
-
-
Burris, J.1
Rietkerk, W.2
Woolf, K.3
-
226
-
-
0036900817
-
Acne vulgaris: A disease of Western civilization
-
Cordain, L.; Lindeberg, S.; Hurtado, M.; Hill, K.; Eaton, S.B.; Brand-Miller, J. Acne vulgaris: A disease of Western civilization. Arch. Dermatol. 2002, 138, 1584–1590
-
(2002)
Arch. Dermatol
, vol.138
, pp. 1584-1590
-
-
Cordain, L.1
Lindeberg, S.2
Hurtado, M.3
Hill, K.4
Eaton, S.B.5
Brand-Miller, J.6
-
227
-
-
79952025848
-
Milk intake and total dairy consumption: Associations with early menarche in NHANES 1999–2004
-
Wiley, A.S. Milk intake and total dairy consumption: Associations with early menarche in NHANES 1999–2004. PLoS ONE 2011, 6, e14685
-
(2011)
Plos ONE
, vol.6
-
-
Wiley, A.S.1
-
228
-
-
84922919186
-
Brazilian Type 1 Diabetes Study Group (BrazDiab1SG). Early age at menarche: A risk factor for overweight or obesity in patients with type 1 diabetes living in urban areas?
-
Gomes, M.B.; Negrato, C.A.; Calliari, L.E.; Brazilian Type 1 Diabetes Study Group (BrazDiab1SG). Early age at menarche: a risk factor for overweight or obesity in patients with type 1 diabetes living in urban areas? Diabetes Res. Clin. Pract. 2015, 107, 23–30
-
(2015)
Diabetes Res. Clin. Pract
, vol.107
, pp. 23-30
-
-
Gomes, M.B.1
Negrato, C.A.2
Calliari, L.E.3
-
229
-
-
84905856492
-
Systematic review and meta-analysis of age at menarche and risk of type 2 diabetes
-
Janghorbani, M.; Mansourian, M.; Hosseini, E. Systematic review and meta-analysis of age at menarche and risk of type 2 diabetes. Acta Diabetol. 2014, 51, 519–528
-
(2014)
Acta Diabetol
, vol.51
, pp. 519-528
-
-
Janghorbani, M.1
Mansourian, M.2
Hosseini, E.3
-
230
-
-
84924725797
-
Early menarche increases the risk of type 2 diabetes in young and middle-aged Korean women
-
Lim, J.S.; Lee, H.S.; Kim, E.Y.; Yi, K.H.; Hwang, J.S. Early menarche increases the risk of type 2 diabetes in young and middle-aged Korean women. Diabet. Med.2015, 32, 521–525
-
(2015)
Diabet. Med
, vol.32
, pp. 521-525
-
-
Lim, J.S.1
Lee, H.S.2
Kim, E.Y.3
Yi, K.H.4
Hwang, J.S.5
-
231
-
-
84864359760
-
The amount and type of dairy product intake and incident type 2 diabetes: Results from the EPIC-InterAct Study
-
Sluijs, I.; Forouhi, N.G.; Beulens, J.W.; van der Schouw, Y.T.; Agnoli, C.; Arriola, L.; Balkau, B.; Barricarte, A.; Boeing, H.; Bueno-de-Mesquita, H.B.; et al. The amount and type of dairy product intake and incident type 2 diabetes: Results from the EPIC-InterAct Study. Am. J. Clin. Nutr. 2012, 96, 382–390
-
(2012)
Am. J. Clin. Nutr
, vol.96
, pp. 382-390
-
-
Sluijs, I.1
Forouhi, N.G.2
Beulens, J.W.3
Van Der Schouw, Y.T.4
Agnoli, C.5
Arriola, L.6
Balkau, B.7
Barricarte, A.8
Boeing, H.9
Bueno-De-Mesquita, H.B.10
-
232
-
-
84894101658
-
Role of the mammalian target of rapamycin (MTOR) complexes in pancreatic β-cell mass regulation
-
Bartolome, A.; Guillén, C. Role of the mammalian target of rapamycin (mTOR) complexes in pancreatic β-cell mass regulation. Vitam. Horm.2014, 95, 425–469
-
(2014)
Vitam. Horm
, vol.95
, pp. 425-469
-
-
Bartolome, A.1
Guillén, C.2
-
233
-
-
81555221602
-
Endoplasmic reticulum stress in the β-cell cell pathogenesis of type 2 diabetes
-
Back, S.H.; Kang, S.W.; Han, J.; Chung, H.A.T. Endoplasmic reticulum stress in the β-cell cell pathogenesis of type 2 diabetes. Exp. Diabetes Res. 2012, 2012, doi:10.1155/2012/618396
-
(2012)
Exp. Diabetes Res
-
-
Back, S.H.1
Kang, S.W.2
Han, J.3
Chung, H.4
-
234
-
-
84861905329
-
Endoplasmic reticulum stress and type 2 diabetes
-
Back, S.H.; Kaufman, R.J. Endoplasmic reticulum stress and type 2 diabetes. Annu. Rev. Biochem. 2012, 81, 767–793
-
(2012)
Annu. Rev. Biochem
, vol.81
, pp. 767-793
-
-
Back, S.H.1
Kaufman, R.J.2
-
235
-
-
40649120732
-
Increased mTORC1 singaling UPRegulates stress
-
Reiling, J.H.; Sabatini, D.M. Increased mTORC1 singaling UPRegulates stress. Mol. Cell 2008, 29, 533–535
-
(2008)
Mol. Cell
, vol.29
, pp. 533-535
-
-
Reiling, J.H.1
Sabatini, D.M.2
-
236
-
-
84855696465
-
MTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE-JNK pathway
-
Kato, H.; Nakajima, S.; Saito, Y.; Takahashi, S.; Katoh, R.; Kitamura, M. mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE-JNK pathway. Cell Death Differ. 2012, 19, 310–320
-
(2012)
Cell Death Differ
, vol.19
, pp. 310-320
-
-
Kato, H.1
Nakajima, S.2
Saito, Y.3
Takahashi, S.4
Katoh, R.5
Kitamura, M.6
-
237
-
-
40649104735
-
Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin singaling and apoptosis
-
Ozcan, U.; Ozcan, L.; Yilmaz, E.; Duvel, K.; Sahin, M.; Manning, B.D.; Hotamisligil, G.S. Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin singaling and apoptosis. Mol. Cell 2008, 29, 541–551
-
(2008)
Mol. Cell
, vol.29
, pp. 541-551
-
-
Ozcan, U.1
Ozcan, L.2
Yilmaz, E.3
Duvel, K.4
Sahin, M.5
Manning, B.D.6
Hotamisligil, G.S.7
-
238
-
-
84860468095
-
Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling
-
Appenzeller-Herzog, C.; Hall, M.N. Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling. Trends Cell Biol. 2012, 22, 274–282
-
(2012)
Trends Cell Biol
, vol.22
, pp. 274-282
-
-
Appenzeller-Herzog, C.1
Hall, M.N.2
-
239
-
-
84899714318
-
Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α
-
Guan, B.J.; Krokowski, D.; Majumder, M.; Schmotzer, C.L.; Kimball, S.R.; Merrick, W.C.; Koromilas, A.E.; Hatzolou, M. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α. J. Biol. Chem. 2014, 289, 12593–12611
-
(2014)
J. Biol. Chem
, vol.289
, pp. 12593-12611
-
-
Guan, B.J.1
Krokowski, D.2
Majumder, M.3
Schmotzer, C.L.4
Kimball, S.R.5
Merrick, W.C.6
Koromilas, A.E.7
Hatzolou, M.8
-
240
-
-
84877578475
-
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
-
Han, J.; Back, S.H.; Hur, J.; Lin, Y.H.; Gildersleeve, R.; Shan, J.; Yuan, C.L.; Krokowski, D.; Wang, S.; Hatzoglou, M.; et al. ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nat. Cell Biol. 2013, 15, 481–490
-
(2013)
Nat. Cell Biol
, vol.15
, pp. 481-490
-
-
Han, J.1
Back, S.H.2
Hur, J.3
Lin, Y.H.4
Gildersleeve, R.5
Shan, J.6
Yuan, C.L.7
Krokowski, D.8
Wang, S.9
Hatzoglou, M.10
-
241
-
-
77957579650
-
Decreased IRS signaling impairs β-cell cycle progression and survival in transgenic mice overexpressing S6K in β-cells
-
Elghazi, L.; Balcazar, N.; Blandino-Rosano, M.; Cras-Méneur, C.; Fatrai, S.; Gould, A.P.; Chi, M.M.; Moley, K.H.; Bernal-Mizrachi, E. Decreased IRS signaling impairs β-cell cycle progression and survival in transgenic mice overexpressing S6K in β-cells. Diabetes 2010, 59, 2390–2399
-
(2010)
Diabetes
, vol.59
, pp. 2390-2399
-
-
Elghazi, L.1
Balcazar, N.2
Blandino-Rosano, M.3
Cras-Méneur, C.4
Fatrai, S.5
Gould, A.P.6
Chi, M.M.7
Moley, K.H.8
Bernal-Mizrachi, E.9
-
242
-
-
39649107702
-
ATF4-mediated induction of 4E-BP1 contributes to pancreatic β cell survival under endoplasmic reticulum stress
-
Yamaguchi, S.; Ishihara, H.; Yamada, T.; Tamura, A.; Usui, M.; Tominaga, R.; Munakata, Y.; Satake, C.; Katagiri, H.; Tashiro, F.; et al. ATF4-mediated induction of 4E-BP1 contributes to pancreatic β cell survival under endoplasmic reticulum stress. Cell Metab. 2008, 7, 269–276
-
(2008)
Cell Metab
, vol.7
, pp. 269-276
-
-
Yamaguchi, S.1
Ishihara, H.2
Yamada, T.3
Tamura, A.4
Usui, M.5
Tominaga, R.6
Munakata, Y.7
Satake, C.8
Katagiri, H.9
Tashiro, F.10
-
243
-
-
84879037139
-
A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux
-
Krokowski, D.; Han, J.; Saikia, M.; Majumder, M.; Yuan, C.L.; Guan, B.J.; Bevilacqua, E.; Bussolati, O.; Bröer, S.; Arvan, P.; et al. A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux. J. Biol. Chem. 2013, 288, 17202–17213
-
(2013)
J. Biol. Chem
, vol.288
, pp. 17202-17213
-
-
Krokowski, D.1
Han, J.2
Saikia, M.3
Majumder, M.4
Yuan, C.L.5
Guan, B.J.6
Bevilacqua, E.7
Bussolati, O.8
Bröer, S.9
Arvan, P.10
-
244
-
-
42349086872
-
Biphasic response of pancreatic β-cell mass to ablation of tuberous sclerosis complex 2 in mice
-
Shigeyama, Y.; Kobayashi, T.; Kido, Y.; Hashimoto, N.; Asahara, S.; Matsuda, T.; Takeda, A.; Inoue, T.; Shibutani, Y.; Koyanagi, M.; et al. Biphasic response of pancreatic β-cell mass to ablation of tuberous sclerosis complex 2 in mice. Mol. Cell. Biol.2008, 28, 2971–2979
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 2971-2979
-
-
Shigeyama, Y.1
Kobayashi, T.2
Kido, Y.3
Hashimoto, N.4
Asahara, S.5
Matsuda, T.6
Takeda, A.7
Inoue, T.8
Shibutani, Y.9
Koyanagi, M.10
-
245
-
-
84862777192
-
The translational landscape of mTOR signalling steers cancer initiation and metastasis
-
Hsieh, A.C.; Liu, Y.; Edlind, M.P.; Ingolia, N.T.; Janes, M.R.; Sher, A.; Shi, E.Y.; Stumpf, C.R.; Christensen, C.; Bonham, M.J.; et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature 2012, 485, 55–61
-
(2012)
Nature
, vol.485
, pp. 55-61
-
-
Hsieh, A.C.1
Liu, Y.2
Edlind, M.P.3
Ingolia, N.T.4
Janes, M.R.5
Sher, A.6
Shi, E.Y.7
Stumpf, C.R.8
Christensen, C.9
Bonham, M.J.10
-
246
-
-
84864914359
-
The impact of cow’s milk-mediated mTORC1-signaling in the initiation and progression of prostate cancer
-
Melnik, B.C.; John, S.M.; Carrera-Bastos, P.; Cordain, L. The impact of cow’s milk-mediated mTORC1-signaling in the initiation and progression of prostate cancer. Nutr. Metab. 2012, 9, doi:10.1186/1743-7075-9-74
-
(2012)
Nutr. Metab
-
-
Melnik, B.C.1
John, S.M.2
Carrera-Bastos, P.3
Cordain, L.4
-
247
-
-
84900471149
-
PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance
-
Edlind, M.P.; Hsieh, A.C. PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance. Asian J. Androl.2014, 16, 378–386
-
(2014)
Asian J. Androl
, vol.16
, pp. 378-386
-
-
Edlind, M.P.1
Hsieh, A.C.2
-
248
-
-
84904619768
-
Expression of phosphorylated-mTOR during the development of prostate cancer
-
Sutherland, S.I.; Pe Benito, R.; Henshall, S.M.; Horvath, L.G.; Kench, J.G. Expression of phosphorylated-mTOR during the development of prostate cancer. Prostate 2014, 74, 1231–1239
-
(2014)
Prostate
, vol.74
, pp. 1231-1239
-
-
Sutherland, S.I.1
Pe Benito, R.2
Henshall, S.M.3
Horvath, L.G.4
Kench, J.G.5
-
249
-
-
84941745204
-
MTOR regulate EMT through RhoA and Rac1 pathway in prostate cancer
-
Chen, X.; Cheng, H.; Pan, T.; Liu, Y.; Su, Y.; Ren, C.; Huang, D.; Zha, X.; Liang, C. mTOR regulate EMT through RhoA and Rac1 pathway in prostate cancer. Mol. Carcinog. 2014, doi:10.1002/mc.22177
-
(2014)
Mol. Carcinog
-
-
Chen, X.1
Cheng, H.2
Pan, T.3
Liu, Y.4
Su, Y.5
Ren, C.6
Huang, D.7
Zha, X.8
Liang, C.9
-
250
-
-
84896702323
-
Regulation of protein translation and c-Jun expression by prostate tumor overexpressed 1
-
Marqués, N.; Sesé, M.; Cánovas, V.; Valente, F.; Bermudo, R.; de Torres, I.; Fernández, Y.; Abasolo, I.; Fernández, P.L.; Contreras, H.; et al. Regulation of protein translation and c-Jun expression by prostate tumor overexpressed 1. Oncogene 2014, 33, 1124–1134
-
(2014)
Oncogene
, vol.33
, pp. 1124-1134
-
-
Marqués, N.1
Sesé, M.2
Cánovas, V.3
Valente, F.4
Bermudo, R.5
De Torres, I.6
Fernández, Y.7
Abasolo, I.8
Fernández, P.L.9
Contreras, H.10
-
251
-
-
84873054570
-
Whole milk intake is associated with prostate cancer-specific mortality among U.S. Male physicians
-
Song, Y.; Chavarro, J.E.; Cao, Y.; Qiu, W.; Mucci, L.; Sesso, H.D.; Stampfer, M.J.; Giovannucci, E.; Pollak, M.; Liu, S.; et al. Whole milk intake is associated with prostate cancer-specific mortality among U.S. male physicians. J. Nutr. 2013, 143, 189–196
-
(2013)
J. Nutr
, vol.143
, pp. 189-196
-
-
Song, Y.1
Chavarro, J.E.2
Cao, Y.3
Qiu, W.4
Mucci, L.5
Sesso, H.D.6
Stampfer, M.J.7
Giovannucci, E.8
Pollak, M.9
Liu, S.10
-
252
-
-
43249086197
-
Animal foods, protein, calcium and prostate cancer risk: The European Prospective Investigation into Cancer and Nutrition
-
Allen, N.E.; Key, T.J.; Appleby, P.N.; Travis, R.C.; Roddam, A.W.; Tjønneland, A.; Johnsen, N.F.; Overvad, K.; Linseisen, J.; Rohrmann, S.; et al. Animal foods, protein, calcium and prostate cancer risk: The European Prospective Investigation into Cancer and Nutrition. Br. J. Cancer 2008, 98, 1574–1581
-
(2008)
Br. J. Cancer
, vol.98
, pp. 1574-1581
-
-
Allen, N.E.1
Key, T.J.2
Appleby, P.N.3
Travis, R.C.4
Roddam, A.W.5
Tjønneland, A.6
Johnsen, N.F.7
Overvad, K.8
Linseisen, J.9
Rohrmann, S.10
-
253
-
-
84855509328
-
Milk intake in early life and risk of advanced prostate cancer
-
Torfadottir, J.E.; Steingrimsdottir, L.; Mucci, L.; Aspelund, T.; Kasperzyk, J.L.; Olafsson, O.; Fall, K.; Tryggvadottir, L.; Harris, T.B.; Launer, L.; et al. Milk intake in early life and risk of advanced prostate cancer. Am. J. Epidemiol.2012, 175, 144–153
-
(2012)
Am. J. Epidemiol
, vol.175
, pp. 144-153
-
-
Torfadottir, J.E.1
Steingrimsdottir, L.2
Mucci, L.3
Aspelund, T.4
Kasperzyk, J.L.5
Olafsson, O.6
Fall, K.7
Tryggvadottir, L.8
Harris, T.B.9
Launer, L.10
-
254
-
-
82555170322
-
PI3K/mTOR signaling regulates prostatic branching morphogenesis
-
Ghosh, S.; Lau, H.; Simons, B.W.; Powell, J.D.; Meyers, D.J.; de Marzo, A.M.; Berman, D.M.; Lotan, T.L. PI3K/mTOR signaling regulates prostatic branching morphogenesis. Dev. Biol. 2011, 360, 329–342
-
(2011)
Dev. Biol
, vol.360
, pp. 329-342
-
-
Ghosh, S.1
Lau, H.2
Simons, B.W.3
Powell, J.D.4
Meyers, D.J.5
De Marzo, A.M.6
Berman, D.M.7
Lotan, T.L.8
-
255
-
-
77953530401
-
The transcriptional regulation of miR-21, its multiple transcripts, and their implication in prostate cancer
-
Ribas, J.; Lupold, S.E. The transcriptional regulation of miR-21, its multiple transcripts, and their implication in prostate cancer. Cell Cycle 2010, 9, 923–929
-
(2010)
Cell Cycle
, vol.9
, pp. 923-929
-
-
Ribas, J.1
Lupold, S.E.2
-
256
-
-
84907420516
-
MicroRNA-21 inhibits p57Kip2 expression in prostate cancer
-
Mishra, S.; Lin, C.L.; Huang, T.H.; Bouamar, H.; Sun, L.Z. MicroRNA-21 inhibits p57Kip2 expression in prostate cancer. Mol. Cancer 2014, 13, 212
-
(2014)
Mol. Cancer
, vol.13
, pp. 212
-
-
Mishra, S.1
Lin, C.L.2
Huang, T.H.3
Bouamar, H.4
Sun, L.Z.5
-
257
-
-
84923686674
-
Controlling RECK miR21 promotes tumor cell invasion and is related to biochemical recurrence in prostate cancer
-
Leite, K.R.; Reis, S.T.; Viana, N.; Morais D.R.; Moura, C.M.; Silva, I.A.; Pontes, J., Jr.; Katz, B.; Srougi, M. Controlling RECK miR21 promotes tumor cell invasion and is related to biochemical recurrence in prostate cancer. J. Cancer 2015, 6, 292–301
-
(2015)
J. Cancer
, vol.6
, pp. 292-301
-
-
Leite, K.R.1
Reis, S.T.2
Viana, N.3
Morais, D.R.4
Moura, C.M.5
Silva, I.A.6
Pontes, J.7
Katz, B.8
Srougi, M.9
-
258
-
-
84905379640
-
Androgen receptor and microRNA-21 axis downregulates transforming growth factor β receptor II (TGFBR2) expression in prostate cancer
-
Mishra, S.; Deng, J.J.; Gowda, P.S.; Rao, M.K.; Lin, C.L.; Chen, C.L.; Huang, T.; Sun, L.Z. Androgen receptor and microRNA-21 axis downregulates transforming growth factor β receptor II (TGFBR2) expression in prostate cancer. Oncogene 2014, 33, 4097–4106
-
(2014)
Oncogene
, vol.33
, pp. 4097-4106
-
-
Mishra, S.1
Deng, J.J.2
Gowda, P.S.3
Rao, M.K.4
Lin, C.L.5
Chen, C.L.6
Huang, T.7
Sun, L.Z.8
-
259
-
-
84857338212
-
Milk stimulates growth of prostate cancer cells in culture
-
Tate, P.L.; Bibb, R.; Larcom, L.L. Milk stimulates growth of prostate cancer cells in culture. Nutr. Cancer 2011, 63, 1361–1366
-
(2011)
Nutr. Cancer
, vol.63
, pp. 1361-1366
-
-
Tate, P.L.1
Bibb, R.2
Larcom, L.L.3
-
260
-
-
84929096229
-
High milk consumption does not affect prostate tumor progression in two mouse models of benign and neoplastic lesions
-
Bernichtein, S.; Pigat, N.; Capiod, T.; Boutillon, F.; Verkarre, V.; Camparo, P.; Viltard, M.; Méjean, A.; Oudard, S.; Souberbielle, J.C.; et al. High milk consumption does not affect prostate tumor progression in two mouse models of benign and neoplastic lesions. PLoS ONE 2015, 10, e0125423
-
(2015)
Plos ONE
-
-
Bernichtein, S.1
Pigat, N.2
Capiod, T.3
Boutillon, F.4
Verkarre, V.5
Camparo, P.6
Viltard, M.7
Méjean, A.8
Oudard, S.9
Souberbielle, J.C.10
-
261
-
-
0028851961
-
Dietary fat and the risk of breast cancer; A prospective study of 25,892 Norwegian women
-
Gaard, M.; Tretli, S.; Løken, E.B. Dietary fat and the risk of breast cancer; A prospective study of 25,892 Norwegian women. Int. J. Cancer 1995, 63, 13–17
-
(1995)
Int. J. Cancer
, vol.63
, pp. 13-17
-
-
Gaard, M.1
Tretli, S.2
Løken, E.B.3
-
262
-
-
35248855633
-
Consumption of commercial whole and non-fat milk increases the incidence of 7,12-dimethylbenz(α)anthracene-induced mammary tumors in rats
-
Qin, L.Q.; Xu, J.Y.; Tezuka, H.; Li, J.; Arita, J.; Hoshi, K.; Sato, A. Consumption of commercial whole and non-fat milk increases the incidence of 7,12-dimethylbenz(α)anthracene-induced mammary tumors in rats. Cancer Detect. Prev. 2007, 31, 339–343
-
(2007)
Cancer Detect. Prev
, vol.31
, pp. 339-343
-
-
Qin, L.Q.1
Xu, J.Y.2
Tezuka, H.3
Li, J.4
Arita, J.5
Hoshi, K.6
Sato, A.7
-
263
-
-
46349088663
-
Milk inhibits the regression of 7,12-dimethylbenz(α)anthracene-induced mammary tumors in ovariectomized rats
-
Qin, L.Q.; Xu, J.Y.; Tezuka, H.; Wang, P.Y.; Hoshi, K. Milk inhibits the regression of 7,12-dimethylbenz(α)anthracene-induced mammary tumors in ovariectomized rats. Nutr. Cancer 2008, 60, 505–510
-
(2008)
Nutr. Cancer
, vol.60
, pp. 505-510
-
-
Qin, L.Q.1
Xu, J.Y.2
Tezuka, H.3
Wang, P.Y.4
Hoshi, K.5
-
265
-
-
43149112727
-
Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: Hypotheses based on epidemiological evidence
-
Martin, L.J.; Boyd, N.F. Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: Hypotheses based on epidemiological evidence. Breast Cancer Res. 2008, 10, doi:10.1186/bcr1831
-
(2008)
Breast Cancer Res
-
-
Martin, L.J.1
Boyd, N.F.2
-
266
-
-
84904574654
-
Insulin-like growth factor-1, growth hormone, and daily cycling estrogen are associated with mammographic density in premenopausal women
-
Frydenberg, H.; Flote, V.G.; Iversen, A.; Finstad, S.E.; Furberg, A.S.; Torjesen, P.A.; Wilsgaard, T.; Schlichting, E.; Ellison, P.T.; Ursin, G.; et al. Insulin-like growth factor-1, growth hormone, and daily cycling estrogen are associated with mammographic density in premenopausal women. Cancer Causes Control. 2014, 25, 891–903
-
(2014)
Cancer Causes Control
, vol.25
, pp. 891-903
-
-
Frydenberg, H.1
Flote, V.G.2
Iversen, A.3
Finstad, S.E.4
Furberg, A.S.5
Torjesen, P.A.6
Wilsgaard, T.7
Schlichting, E.8
Ellison, P.T.9
Ursin, G.10
-
267
-
-
84929119583
-
Induction of anterior gradient 2 (AGR2) plays a key role in insulin-like growth factor-1 (IGF-1)-induced breast cancer cell proliferation and migration
-
Li, Z.; Wu, Z.; Chen, H.; Zhu, Q.; Gao, G.; Hu, L.; Negi, H.; Kamle, S.; Li, D. Induction of anterior gradient 2 (AGR2) plays a key role in insulin-like growth factor-1 (IGF-1)-induced breast cancer cell proliferation and migration. Med. Oncol. 2015, 32, 577
-
(2015)
Med. Oncol
, vol.32
, pp. 577
-
-
Li, Z.1
Wu, Z.2
Chen, H.3
Zhu, Q.4
Gao, G.5
Hu, L.6
Negi, H.7
Kamle, S.8
Li, D.9
-
268
-
-
1942436958
-
Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: Systematic review and meta-regression analysis
-
Renehan, A.G.; Zwahlen, M.; Minder, C.; O’Dwyer, S.T.; Shalet, S.M.; Egger, M. Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: Systematic review and meta-regression analysis. Lancet 2004, 363, 1346–1353
-
(2004)
Lancet
, vol.363
, pp. 1346-1353
-
-
Renehan, A.G.1
Zwahlen, M.2
Minder, C.3
O’Dwyer, S.T.4
Shalet, S.M.5
Egger, M.6
-
269
-
-
84924311398
-
Prediagnostic plasma IGFBP-1, IGF-1 and risk of prostate cancer
-
Cao, Y.; Nimptsch, K.; Shui, I.M.; Platz, E.A.; Wu, K.; Pollak, M.N.; Kenfield, S.A.; Stampfer, M.J.; Giovannucci, E.L. Prediagnostic plasma IGFBP-1, IGF-1 and risk of prostate cancer. Int. J. Cancer 2015, 136, 2418–2426
-
(2015)
Int. J. Cancer
, vol.136
, pp. 2418-2426
-
-
Cao, Y.1
Nimptsch, K.2
Shui, I.M.3
Platz, E.A.4
Wu, K.5
Pollak, M.N.6
Kenfield, S.A.7
Stampfer, M.J.8
Giovannucci, E.L.9
-
270
-
-
33745115859
-
Insulin-like growth factor (IGF)-I, IGF binding protein-3, and breast cancer risk: Eight years on
-
Renehan, A.G.; Harvie, M.; Howell, A. Insulin-like growth factor (IGF)-I, IGF binding protein-3, and breast cancer risk: Eight years on. Endocr. Relat. Cancer 2006, 13, 273–278
-
(2006)
Endocr. Relat. Cancer
, vol.13
, pp. 273-278
-
-
Renehan, A.G.1
Harvie, M.2
Howell, A.3
-
271
-
-
84924236911
-
The role of the insulin-like growth factor-1 system in breast cancer
-
Christopoulos, P.F.; Msaouel, P.; Koutsilieris, M. The role of the insulin-like growth factor-1 system in breast cancer. Mol. Cancer2015, 14, doi:10.1186/s12943-015-0291-7
-
(2015)
Mol. Cancer
, vol.14
-
-
Christopoulos, P.F.1
Msaouel, P.2
Koutsilieris, M.3
-
272
-
-
84857945379
-
Akt and ERK control the proliferative response of mammary epithelial cells to the growth factors IGF-1 and EGF through the cell cycle inhibitor p57Kip2
-
Worster, D.T.; Schmelzle, T.; Solimini, N.L.; Lightcap, E.S.; Millard, B.; Mills, G.B.; Brugge, J.S.; Albeck, J.G. Akt and ERK control the proliferative response of mammary epithelial cells to the growth factors IGF-1 and EGF through the cell cycle inhibitor p57Kip2. Sci. Signal.2012, 5, ra19
-
(2012)
Sci. Signal
, vol.5
-
-
Worster, D.T.1
Schmelzle, T.2
Solimini, N.L.3
Lightcap, E.S.4
Millard, B.5
Mills, G.B.6
Brugge, J.S.7
Albeck, J.G.8
-
273
-
-
84957954240
-
Serum microRNA-21 as a potential diagnostic biomarker for breast cancer: A systematic review and meta-analysis
-
Li, S.; Yang, X.; Yang, J.; Zhen, J.; Zhang, D. Serum microRNA-21 as a potential diagnostic biomarker for breast cancer: A systematic review and meta-analysis. Clin. Exp. Med.2014, doi:10.1007/s10238-014-0332-3
-
(2014)
Clin. Exp. Med
-
-
Li, S.1
Yang, X.2
Yang, J.3
Zhen, J.4
Zhang, D.5
-
274
-
-
84923651749
-
Quantitative measurement of serum microRNA-21 expression in relation to breast cancer metastasis in Chinese females
-
Wang, G.; Wang, L.; Sun, S.; Wu, J.; Wang, Q. Quantitative measurement of serum microRNA-21 expression in relation to breast cancer metastasis in Chinese females. Ann. Lab. Med.2015, 35, 226–232
-
(2015)
Ann. Lab. Med
, vol.35
, pp. 226-232
-
-
Wang, G.1
Wang, L.2
Sun, S.3
Wu, J.4
Wang, Q.5
-
275
-
-
84911495931
-
Prognostic and clinicopathological significance of microRNA-21 overexpression in breast cancer: A meta-analysis
-
Pan, F.; Mao, H.; Deng, L.; Li, G.; Geng, P. Prognostic and clinicopathological significance of microRNA-21 overexpression in breast cancer: A meta-analysis. Int. J. Clin. Exp. Pathol. 2014, 7, 5622–5633
-
(2014)
Int. J. Clin. Exp. Pathol
, vol.7
, pp. 5622-5633
-
-
Pan, F.1
Mao, H.2
Deng, L.3
Li, G.4
Geng, P.5
-
276
-
-
84896723630
-
MicroRNA-21 in breast cancer: Diagnostic and prognostic potential
-
Chen, J.; Wang, X. MicroRNA-21 in breast cancer: Diagnostic and prognostic potential. Clin. Transl. Oncol. 2014, 16, 225–233
-
(2014)
Clin. Transl. Oncol
, vol.16
, pp. 225-233
-
-
Chen, J.1
Wang, X.2
-
277
-
-
79959524843
-
Noncanonical TGF-β signaling during mammary tumorigenesis
-
Parvani, J.G.; Taylor, M.A.; Schiemann, W.P. Noncanonical TGF-β signaling during mammary tumorigenesis. J. Mammary Gland Biol. Neoplasia 2011, 16, 127–146
-
(2011)
J. Mammary Gland Biol. Neoplasia
, vol.16
, pp. 127-146
-
-
Parvani, J.G.1
Taylor, M.A.2
Schiemann, W.P.3
-
278
-
-
84876231995
-
Prognostic and therapeutic implications of mTORC1 and Rictor expression in human breast cancer
-
Wazir, U.; Newbold, R.F.; Jiang, W.G.; Sharma, A.K. Mokbel, K. Prognostic and therapeutic implications of mTORC1 and Rictor expression in human breast cancer. Oncol. Rep. 2013, 29, 1969–1974
-
(2013)
Oncol. Rep
, vol.29
, pp. 1969-1974
-
-
Wazir, U.1
Newbold, R.F.2
Jiang, W.G.3
Sharma, A.K.4
Mokbel, K.5
-
279
-
-
84937638607
-
Associations between diabetes medication use and risk of second breast cancer events and mortality
-
Calip, G.S.; Yu, O.; Hoskins, K.F.; Boudreau, D.M. Associations between diabetes medication use and risk of second breast cancer events and mortality. Cancer Causes Control 2015, 26, 1065–1077
-
(2015)
Cancer Causes Control
, vol.26
, pp. 1065-1077
-
-
Calip, G.S.1
Yu, O.2
Hoskins, K.F.3
Boudreau, D.M.4
-
280
-
-
84927127799
-
Attenuating tumour angiogenesis: A preventive role of metformin against breast cancer
-
Gao, S.; Jiang, J.; Li, P.; Song, H.; Wang, W.; Li, C.; Kong, D. Attenuating tumour angiogenesis: A preventive role of metformin against breast cancer. Biomed. Res. Int. 2015, 2015, doi:10.1155/2015/592523
-
(2015)
Biomed. Res. Int
, vol.2015
-
-
Gao, S.1
Jiang, J.2
Li, P.3
Song, H.4
Wang, W.5
Li, C.6
Kong, D.7
-
281
-
-
84926500195
-
Recent advances in the use of metformin: Can treating diabetes prevent breast cancer?
-
Hatoum, D.; McGowan, E.M. Recent advances in the use of metformin: Can treating diabetes prevent breast cancer? Biomed. Res. Int. 2015, 2015, doi:10.1155/2015/548436
-
(2015)
Biomed. Res. Int
, vol.2015
-
-
Hatoum, D.1
McGowan, E.M.2
-
283
-
-
84922460867
-
Parkinson disease and Alzheimer disease: Environmental risk factors
-
Campdelacreu, J. Parkinson disease and Alzheimer disease: Environmental risk factors. Neurologia 2014, 29, 541–549
-
(2014)
Neurologia
, vol.29
, pp. 541-549
-
-
Campdelacreu, J.1
-
284
-
-
84908472846
-
Dairy foods intake and risk of Parkinson’s disease: A dose-response meta-analysis of prospective cohort studies
-
Jiang, W.; Ju, C.; Jiang, H.; Zhang, D. Dairy foods intake and risk of Parkinson’s disease: A dose-response meta-analysis of prospective cohort studies. Eur. J. Epidemiol. 2014, 29, 613–619
-
(2014)
Eur. J. Epidemiol
, vol.29
, pp. 613-619
-
-
Jiang, W.1
Ju, C.2
Jiang, H.3
Zhang, D.4
-
285
-
-
84874936774
-
Dietary and lifestyle variables in relation to incidence of Parkinson’s disease in Greece
-
Kyrozis, A.; Ghika, A.; Stathopoulos, P.; Vassilopoulos, D.; Trichopoulos, D.; Trichopoulou, A. Dietary and lifestyle variables in relation to incidence of Parkinson’s disease in Greece. Eur. J. Epidemiol. 2013, 28, 67–77
-
(2013)
Eur. J. Epidemiol
, vol.28
, pp. 67-77
-
-
Kyrozis, A.1
Ghika, A.2
Stathopoulos, P.3
Vassilopoulos, D.4
Trichopoulos, D.5
Trichopoulou, A.6
-
286
-
-
84925436842
-
MTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy
-
Perluigi, M.; di domenico, F.; Butterfield, D.A. mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy. Neurobiol. Dis. 2015, in press.
-
(2015)
Neurobiol
-
-
Perluigi, M.1
Di Domenico, F.2
Butterfield, D.A.3
-
287
-
-
84901364520
-
Protein phosphorylation in neurodegeneration: Friend or foe? Front
-
Tenreiro, S.; Eckermann, K.; Outeiro, T.F. Protein phosphorylation in neurodegeneration: Friend or foe? Front. Mol. Neurosci. 2014, 7, doi:10.3389/fnmol.2014.00042
-
(2014)
Mol. Neurosci
, vol.7
-
-
Tenreiro, S.1
Eckermann, K.2
Outeiro, T.F.3
-
288
-
-
84877803859
-
MTOR regulates tau phosphorylation and degradation: Implications for Alzheimer’s disease and other tauopathies
-
Caccamo, A.; Magrì, A.; Medina, D.X.; Wisely, E.V.; López-Aranda, M.F.; Silva, A.J.; Oddo, S. mTOR regulates tau phosphorylation and degradation: Implications for Alzheimer’s disease and other tauopathies. Aging Cell 2013, 12, 370–380
-
(2013)
Aging Cell
, vol.12
, pp. 370-380
-
-
Caccamo, A.1
Magrì, A.2
Medina, D.X.3
Wisely, E.V.4
López-Aranda, M.F.5
Silva, A.J.6
Oddo, S.7
-
289
-
-
77956305343
-
Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-β levels in a mouse model of Alzheimer’s disease
-
Spilman, P.; Podlutskaya, N.; Hart, M.J.; Debnath, J.; Gorostiza, O.; Bredesen, D.; Richardson, A.; Strong, R.; Galvan, V. Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-β levels in a mouse model of Alzheimer’s disease. PLoS ONE 2010, 5, e9979
-
(2010)
Plos ONE
, vol.5
-
-
Spilman, P.1
Podlutskaya, N.2
Hart, M.J.3
Debnath, J.4
Gorostiza, O.5
Bredesen, D.6
Richardson, A.7
Strong, R.8
Galvan, V.9
-
290
-
-
84938061050
-
How longevity research can lead to therapies for Alzheimer’s disease: The rapamycin story
-
Richardson, A.; Galvan, V.; Lin, A.L.; Oddo, S. How longevity research can lead to therapies for Alzheimer’s disease: The rapamycin story. Exp. Gerontol.2015, 68, 51–58
-
(2015)
Exp. Gerontol
, vol.68
, pp. 51-58
-
-
Richardson, A.1
Galvan, V.2
Lin, A.L.3
Oddo, S.4
-
291
-
-
78650746798
-
Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling
-
Kickstein, E.; Krauss, S.; Thornhill, P.; Rutschow, D.; Zeller, R.; Sharkey, J.; Williamson, R.; Fuchs, M.; Köhler, A.; Glossmann, H.; et al. Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling. Proc. Natl. Acad. Sci. USA 2010, 107, 21830–21835
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 21830-21835
-
-
Kickstein, E.1
Krauss, S.2
Thornhill, P.3
Rutschow, D.4
Zeller, R.5
Sharkey, J.6
Williamson, R.7
Fuchs, M.8
Köhler, A.9
Glossmann, H.10
-
292
-
-
84938096122
-
Formula feeding promotes adipogenic, diabetogenic, hypertonic and allergic mTORC1-programming
-
1st ed.; Preedy, V.R., Watson, R.R., Zibadi, S., Eds.; Wagenigen Academic Publishers: Wageningen, The Netherlands
-
Melnik, B.C. Formula feeding promotes adipogenic, diabetogenic, hypertonic and allergic mTORC1-programming. In Handbook of Dietary and Nutritional Aspects of Bottle Feeding, 1st ed.; Preedy, V.R., Watson, R.R., Zibadi, S., Eds.; Wagenigen Academic Publishers: Wageningen, The Netherlands, 2014; pp. 545–568
-
(2014)
Handbook of Dietary and Nutritional Aspects of Bottle Feeding
, pp. 545-568
-
-
Melnik, B.C.1
-
293
-
-
0141856621
-
The Trojan exosome hypothesis
-
Gould, S.J.; Booth, A.M.; Hildreth, J.E. The Trojan exosome hypothesis. Proc. Natl. Acad. Sci. USA 2003, 100, 10592–10597
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10592-10597
-
-
Gould, S.J.1
Booth, A.M.2
Hildreth, J.E.3
-
294
-
-
84924331365
-
Differential temporal expression of milk miRNA during the lactation cycle of the marsupial tammar wallaby (Macropus eugenii)
-
Modepalli, V.; Kumar, A.; Hinds, L.A.; Sharp, J.A.; Nicholas, K.R.; Lefevre, C. Differential temporal expression of milk miRNA during the lactation cycle of the marsupial tammar wallaby (Macropus eugenii). BMC Genomics 2014, 15, 1012
-
(2014)
BMC Genomics
, vol.15
, pp. 1012
-
-
Modepalli, V.1
Kumar, A.2
Hinds, L.A.3
Sharp, J.A.4
Nicholas, K.R.5
Lefevre, C.6
-
295
-
-
0006460431
-
An experimental study of the use of unsweetened evaporated milk for the preparation of infant feeding formulas
-
Marriott, M.; Schoenthal, J. An experimental study of the use of unsweetened evaporated milk for the preparation of infant feeding formulas. Arch. Pediatr. 1929, 46, 135–148
-
(1929)
Arch. Pediatr
, vol.46
, pp. 135-148
-
-
Marriott, M.1
Schoenthal, J.2
-
296
-
-
67349194955
-
From breast to bottle: A history of modern infant feeding
-
Bryder, L. From breast to bottle: A history of modern infant feeding. Endeavour 2009, 54–59
-
(2009)
Endeavour
, pp. 54-59
-
-
Bryder, L.1
-
297
-
-
0011164979
-
Prolonging the life span
-
McCay, C.M.; Crowell, M.F. Prolonging the life span. Sci. Mon. 1934, 39, 405–414
-
(1934)
Sci. Mon
, vol.39
, pp. 405-414
-
-
McCay, C.M.1
Crowell, M.F.2
-
298
-
-
57349100793
-
Hypothesis: Is lactose a dietary risk factor for ischaemic heart disease?
-
Segall, J.J. Hypothesis: Is lactose a dietary risk factor for ischaemic heart disease? Int. J. Epidemiol. 2008, 37, 1204–1208
-
(2008)
Int. J. Epidemiol
, vol.37
, pp. 1204-1208
-
-
Segall, J.J.1
-
299
-
-
84920658497
-
Lactose intolerance and risk of lung, breast and ovarian cancers: Aetiological clues from a population-based study in Sweden
-
Ji, J.; Sundquist, J.; Sundquist, K. Lactose intolerance and risk of lung, breast and ovarian cancers: Aetiological clues from a population-based study in Sweden. Br. J. Cancer 2015, 112, 149–152
-
(2015)
Br. J. Cancer
, vol.112
, pp. 149-152
-
-
Ji, J.1
Sundquist, J.2
Sundquist, K.3
-
300
-
-
84914165449
-
Can people with type 2 diabetes life longer than those without? A comparison of mortality in people initiatd with metformin or sulphonylurea monotherapy and matched, non-diabetic controls
-
Bannister, C.A.; Holden, S.E.; Jenkins-Jones, S.; Morgan, C.L.; Halcox, J.P.; Schernthaner, G.; Mukherjee, J.; Currie, C.J. Can people with type 2 diabetes life longer than those without? A comparison of mortality in people initiatd with metformin or sulphonylurea monotherapy and matched, non-diabetic controls. Diabetes Obes. Metab. 2014, 16, 1165–1173
-
(2014)
Diabetes Obes. Metab
, vol.16
, pp. 1165-1173
-
-
Bannister, C.A.1
Holden, S.E.2
Jenkins-Jones, S.3
Morgan, C.L.4
Halcox, J.P.5
Schernthaner, G.6
Mukherjee, J.7
Currie, C.J.8
-
301
-
-
77955722198
-
Revisiting the antagonistic peiotropy theory of aging. TOR-driven program and quasi-program
-
Blagosklonny, M.V. Revisiting the antagonistic peiotropy theory of aging. TOR-driven program and quasi-program. Cell Cycle 2010, 9, 3151–3156
-
(2010)
Cell Cycle
, vol.9
, pp. 3151-3156
-
-
Blagosklonny, M.V.1
-
302
-
-
84908409210
-
Milk and mortality
-
Schooling, C.M. Milk and mortality. BMJ 2014, 349, g6205
-
(2014)
BMJ
, vol.349
-
-
Schooling, C.M.1
-
303
-
-
84877798880
-
High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan
-
Dellago, H.; Preschitz-Kammerhofer, B.; Terlecki-Zaniewicz, L.; Schreiner C.; Fortschegger, K.; Chang, M.W.; Hackl, M.; Monteforte, R.; Kühnel, H.; Schosserer, M.; et al. High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan. Aging Cell 2013, 12, 446–458
-
(2013)
Aging Cell
, vol.12
, pp. 446-458
-
-
Dellago, H.1
Preschitz-Kammerhofer, B.2
Terlecki-Zaniewicz, L.3
Schreiner, C.4
Fortschegger, K.5
Chang, M.W.6
Hackl, M.7
Monteforte, R.8
Kühnel, H.9
Schosserer, M.10
-
304
-
-
84865737617
-
MiR-21 modulates hTERT through a STAT3-dependent manner on glioblastoma cell growth
-
Wang, Y.Y.; Sun, G.; Luo, H.; Wang, X.F.; Lan, F.M.; Yue, X.; Fu, L.S.; Pu, P.Y.; Kang, C.S.; Liu, N.; et al. MiR-21 modulates hTERT through a STAT3-dependent manner on glioblastoma cell growth. CNS Neurosci. Ther. 2012, 18, 722–728
-
(2012)
CNS Neurosci. Ther
, vol.18
, pp. 722-728
-
-
Wang, Y.Y.1
Sun, G.2
Luo, H.3
Wang, X.F.4
Lan, F.M.5
Yue, X.6
Fu, L.S.7
Pu, P.Y.8
Kang, C.S.9
Liu, N.10
-
305
-
-
84870741421
-
Age-related differences in the expression of circulating microRNAs: MiR-21 as a new circulating marker of inflammaging
-
Olivieri, F.; Spazzafumo, L.; Santini, G.; Lazzarini, R.; Albertini, M.C.; Rippo, M.R.; Galeazzi, R.; Abbatecola, A.M.; Marcheselli, F.; Monti, D.; et al. Age-related differences in the expression of circulating microRNAs: miR-21 as a new circulating marker of inflammaging. Mech. Ageing Dev.2012, 133, 675–685
-
(2012)
Mech. Ageing Dev
, vol.133
, pp. 675-685
-
-
Olivieri, F.1
Spazzafumo, L.2
Santini, G.3
Lazzarini, R.4
Albertini, M.C.5
Rippo, M.R.6
Galeazzi, R.7
Abbatecola, A.M.8
Marcheselli, F.9
Monti, D.10
-
306
-
-
77955661579
-
MicroRNA-21 in cardiovascular disease
-
Cheng, Y.; Zhang, C. MicroRNA-21 in cardiovascular disease. J. Cardiovasc. Transl. Res. 2010, 3, 251–255
-
(2010)
J. Cardiovasc. Transl. Res
, vol.3
, pp. 251-255
-
-
Cheng, Y.1
Zhang, C.2
-
307
-
-
84880906480
-
MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic diesease
-
Hulsmans, M.; Holvoet, P. MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic diesease. Cardiovasc. Res.2013, 100, 7–18
-
(2013)
Cardiovasc. Res
, vol.100
, pp. 7-18
-
-
Hulsmans, M.1
Holvoet, P.2
-
308
-
-
84881129444
-
Role of microRNA-21 in regulating 3T3-L1 adipocyte differentiation and adiponectin expression
-
Kang, M.; Yan, L.M.; Zhang, W.Y.; Li, Y.M.; Tang, A.Z.; Ou, H.S. Role of microRNA-21 in regulating 3T3-L1 adipocyte differentiation and adiponectin expression. Mol. Biol. Rep. 2013, 40, 5027–5034
-
(2013)
Mol. Biol. Rep
, vol.40
, pp. 5027-5034
-
-
Kang, M.1
Yan, L.M.2
Zhang, W.Y.3
Li, Y.M.4
Tang, A.Z.5
Ou, H.S.6
-
309
-
-
79953078936
-
Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity
-
Keller, P.; Gburcik, V.; Petrovic, N.; Gallagher, I.J.; Nedergaard, J.; Cannon, B.; Timmons, J.A. Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity. BMC Endocr. Disord. 2011, 11, 7, doi:10.1186/1472-6823-11-7
-
(2011)
BMC Endocr. Disord
, vol.11
-
-
Keller, P.1
Gburcik, V.2
Petrovic, N.3
Gallagher, I.J.4
Nedergaard, J.5
Cannon, B.6
Timmons, J.A.7
-
310
-
-
84910156341
-
Long-term inhibition of miR-21 leads to reduction of obesity in db/db mice
-
Seeger, T.; Fischer, A.; Muhly-Reinholz, M.; Zeiher, A.M.; Dimmeler, S. Long-term inhibition of miR-21 leads to reduction of obesity in db/db mice. Obesity (Silver Spring) 2014, 22, 2352–2360
-
(2014)
Obesity (Silver Spring)
, vol.22
, pp. 2352-2360
-
-
Seeger, T.1
Fischer, A.2
Muhly-Reinholz, M.3
Zeiher, A.M.4
Dimmeler, S.5
-
312
-
-
0000055057
-
Pleiotropy, natural selection and the evolution of senescence
-
Williams, G.C. Pleiotropy, natural selection and the evolution of senescence. Evolution 1957, 11, 398–411
-
(1957)
Evolution
, vol.11
, pp. 398-411
-
-
Williams, G.C.1
-
313
-
-
84891887779
-
Aging is not programmed: Genetic pseudo-program is a shadow of developmental growth
-
Blagosklonny, M.V. Aging is not programmed: Genetic pseudo-program is a shadow of developmental growth. Cell Cycle 2013, 12, 3736–3742
-
(2013)
Cell Cycle
, vol.12
, pp. 3736-3742
-
-
Blagosklonny, M.V.1
-
314
-
-
77955747346
-
Less is more: A key role for the conserved nutrient sensing TOR pathway in aging
-
Kapahi, P.; Chen, D.; Rogers, A.N.; Katewa, S.D.; Li, P.W.; Thomas, E.L.; Kockel, L. With TOR less is more: A key role for the conserved nutrient sensing TOR pathway in aging. Cell Metab. 2010, 11, 453–365
-
(2010)
Cell Metab
, vol.11
, pp. 365-453
-
-
Kapahi, P.1
Chen, D.2
Rogers, A.N.3
Katewa, S.D.4
Li, P.W.5
Thomas, E.L.6
Kockel, L.7
With, T.8
-
315
-
-
84938131800
-
Human milk microRNA and total RNA differ depending on milk fractionation
-
Alsaweed, M.; Hepworth, A.R.; Lefèvre, C.; Hartmann, P.E.; Geddes, D.T.; Hassiotou, F. Human milk microRNA and total RNA differ depending on milk fractionation. J. Cell. Biochem. 2015, in press.
-
(2015)
J. Cell. Biochem
-
-
Alsaweed, M.1
Hepworth, A.R.2
Lefèvre, C.3
Hartmann, P.E.4
Geddes, D.T.5
Hassiotou, F.6
-
316
-
-
62949152092
-
Milk-the promoter of chronic Western diseases
-
Melnik, B.C. Milk-the promoter of chronic Western diseases. Med. Hypotheses 2009, 72, 631–639.
-
(2009)
Med. Hypotheses
, vol.72
, pp. 631-639
-
-
Melnik, B.C.1
|