The Decapping Scavenger Enzyme DCS-1 Controls MicroRNA Levels in Caenorhabditis elegans

Molecular Cell

Volumn 50, Issue 2, 2013, Pages 281-287

  Bossé, Gabriel D ^a   Rüegger, Stefan ^b,c   Ow, Maria C ^d   Vasquez Rifo, Alejandro ^a   Rondeau, Evelyne L ^a   Ambros, Victor R ^d   Großhans, Helge ^b   Simard, Martin J ^a  

^a LAVAL UNIVERSITY   (Canada)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DECAPPING SCAVENGER PROTEIN DCS 1; EXONUCLEASE; EXONUCLEASE XRN 1; MICRORNA; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; GENETIC REGULATION; MUTATION; NONHUMAN; RNA DEGRADATION;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; EXORIBONUCLEASES; GENE EXPRESSION; MICRORNAS; MUTATION; N-GLYCOSYL HYDROLASES; RNA INTERFERENCE; RNA STABILITY; RNA, HELMINTH; RNA-INDUCED SILENCING COMPLEX;

ANIMALIA; CAENORHABDITIS ELEGANS; METAZOA;

EID: 84876865975     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2013.02.023     Document Type: Article

References (36)

1. Bajan S., Hutvagner G. Another " loophole" in miRNA processing. Mol. Cell 2011, 44:345-347.
2. Brenner S. The genetics of Caenorhabditis elegans. Genetics 1974, 77:71-94.
3. Chatterjee S., Grosshans H. Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 2009, 461:546-549.
4. Chatterjee S., Fasler M., Büssing I., Grosshans H. Target-mediated protection of endogenous microRNAs in C. elegans. Dev. Cell 2011, 20:388-396.
5. Cohen L.S., Mikhli C., Friedman C., Jankowska-Anyszka M., Stepinski J., Darzynkiewicz E., Davis R.E. Nematode m7GpppG and m3(2,2,7)GpppG decapping: activities in Ascaris embryos and characterization of C. elegans scavenger DcpS. RNA 2004, 10:1609-1624.
6. Ebert M.S., Sharp P.A. Roles for microRNAs in conferring robustness to biological processes. Cell 2012, 149:515-524.
7. Elkayam E., Kuhn C.D., Tocilj A., Haase A.D., Greene E.M., Hannon G.J., Joshua-Tor L. The structure of human argonaute-2 in complex with miR-20a. Cell 2012, 150:100-110.
8. Esteller M. Non-coding RNAs in human disease. Nat. Rev. Genet. 2011, 12:861-874.
9. Grishok A., Pasquinelli A.E., Conte D., Li N., Parrish S., Ha I., Baillie D.L., Fire A., Ruvkun G., Mello C.C. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 2001, 106:23-34.
10. Hu H., Gatti R.A. MicroRNAs: new players in the DNA damage response. J Mol Cell Biol 2011, 3:151-158.
11. Huntzinger E., Izaurralde E. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat. Rev. Genet. 2011, 12:99-110.
12. Hutvagner G., Simard M.J., Mello C.C., Zamore P.D. Sequence-specific inhibition of small RNA function. PLoS Biol. 2004, 2:E98.
13. Kai Z.S., Pasquinelli A.E. MicroRNA assassins: factors that regulate the disappearance of miRNAs. Nat. Struct. Mol. Biol. 2010, 17:5-10.
14. Kaufman E.J., Miska E.A. The microRNAs of Caenorhabditis elegans. Semin. Cell Dev. Biol. 2010, 21:728-737.
15. Kim V.N., Han J., Siomi M.C. Biogenesis of small RNAs in animals. Nat. Rev. Mol. Cell Biol. 2009, 10:126-139.
16. Krol J., Loedige I., Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 2010, 11:597-610.
17. Kwasnicka D.A., Krakowiak A., Thacker C., Brenner C., Vincent S.R. Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1. J. Biol. Chem. 2003, 278:39051-39058.
18. Lall S., Piano F., Davis R.E. Caenorhabditis elegans decapping proteins: localization and functional analysis of Dcp1, Dcp2, and DcpS during embryogenesis. Mol. Biol. Cell 2005, 16:5880-5890.
19. Lehrbach N.J., Armisen J., Lightfoot H.L., Murfitt K.J., Bugaut A., Balasubramanian S., Miska E.A. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Nat. Struct. Mol. Biol. 2009, 16:1016-1020.
20. Leung A.K., Sharp P.A. MicroRNA functions in stress responses. Mol. Cell 2010, 40:205-215.
21. Liu H., Kiledjian M. Scavenger decapping activity facilitates 5' to 3' mRNA decay. Mol. Cell. Biol. 2005, 25:9764-9772.
22. Liu H., Rodgers N.D., Jiao X., Kiledjian M. The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases. EMBO J. 2002, 21:4699-4708.
23. Mello C., Fire A. DNA transformation. Methods Cell Biol. 1995, 48:451-482.
24. Mendell J.T., Olson E.N. MicroRNAs in stress signaling and human disease. Cell 2012, 148:1172-1187.
25. Nakanishi K., Weinberg D.E., Bartel D.P., Patel D.J. Structure of yeast Argonaute with guide RNA. Nature 2012, 486:368-374.
26. Newman M.A., Mani V., Hammond S.M. Deep sequencing of microRNA precursors reveals extensive 3' end modification. RNA 2011, 17:1795-1803.
27. Pasquinelli A.E. MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat. Rev. Genet. 2012, 13:271-282.
28. Ramachandran V., Chen X. Degradation of microRNAs by a family of exoribonucleases in Arabidopsis. Science 2008, 321:1490-1492.
29. Reinhart B.J., Slack F.J., Basson M., Pasquinelli A.E., Bettinger J.C., Rougvie A.E., Horvitz H.R., Ruvkun G. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 2000, 403:901-906.
30. Resnick T.D., McCulloch K.A., Rougvie A.E. miRNAs give worms the time of their lives: small RNAs and temporal control in Caenorhabditis elegans. Dev. Dyn. 2010, 239:1477-1489.
31. Rüegger S., Großhans H. MicroRNA turnover: when, how, and why. Trends Biochem. Sci. 2012, 37:436-446.
32. Schirle N.T., MacRae I.J. The crystal structure of human Argonaute2. Science 2012, 336:1037-1040.
33. Sinturel F., Bréchemier-Baey D., Kiledjian M., Condon C., Bénard L. Activation of 5'-3' exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast. Proc. Natl. Acad. Sci. USA 2012, 109:8264-8269.
34. Slack F.J., Basson M., Liu Z., Ambros V., Horvitz H.R., Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol. Cell 2000, 5:659-669.
35. Vasquez-Rifo A., Jannot G., Armisen J., Labouesse M., Bukhari S.I., Rondeau E.L., Miska E.A., Simard M.J. Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2. PLoS ONE 2012, 7:e33750.
36. Wang Z., Kiledjian M. Functional link between the mammalian exosome and mRNA decapping. Cell 2001, 107:751-762.